ABSTRACT In Brazil, the estimated number of new cancer cases between 2020 and 2022 is 625 thousand, and the most prevalent carcinomas are primarily skin (non-melanoma), followed by those of the breast, prostate, colon, and rectum. Although breast carcinoma still has a high mortality rate, it has a good prognosis due to the increase in early diagnosis and the evolution of anticancer treatments. The proposed treatment can be isolated or associated with resective surgery, radiotherapy, chemotherapy, and/or hormone replacement. Chemotherapy generates extensive immunosuppression and affects both healthy and altered cells, and the cytotoxicity of the treatment is an important effect that can cause lesions on the oral mucosa. Severity is related to the type of chemotherapeutic agent, treatment time, the dose used, and the individual’s age. Additionally, chemotherapy treatment can exacerbate preexisting conditions in the individual and cause greater discomfort during treatment. Therefore, monitoring oral health before, during, and after anticancer therapy is essential. The objective of this work is to report a clinical case of dental emergency in a patient after the first cycle of doxorubicin- cyclophosphamide-paclitaxel (ACTdd) to treat breast cancer.

RESUMO No Brasil, a estimativa de novos casos de câncer entre os anos 2020 a 2022 é de 625 mil, sendo os carcinomas mais prevalentes, principalmente os de pele (não melanoma), seguido pelos de mama e próstata, cólon e reto. O carcinoma de mama, embora ainda possua uma alta taxa de mortalidade, apresenta um bom prognóstico devido ao aumento do diagnóstico precoce e evolução dos tratamentos antineoplásicos. O tratamento proposto pode ser isolado ou associado, através de cirurgia ressectiva, radioterapia, quimioterapia e/ou reposição hormonal. A quimioterapia gera extensa imunossupressão e atinge tanto as células saudáveis como as alteradas, tendo a citotoxicidade do tratamento um importante efeito que pode gerar lesões na mucosa oral. A severidade está relacionada ao tipo de quimioterápico, ao tempo de tratamento, bem como à dose utilizada e à idade do indivíduo. Adicionalmente, o tratamento quimioterápico pode exacerbar condições previamente instaladas no indivíduo e causar um maior desconforto durante o tratamento. Desta forma, o monitoramento da saúde bucal antes, durante e após a terapia antineoplásica é essencial. O objetivo desse trabalho é relatar um caso clínico de urgência odontológica em uma paciente após o primeiro ciclo de doxorrubicina-ciclofosfamida-paclitaxel (ACTdd) para o tratamento de câncer de mama.

Resumo Introdução Diante da alta incidência das doenças cardiovasculares, muitos são os pacientes que fazem uso de medicações para prevenção e tratamento dessas desordens. Consequentemente, o número de pessoas em uso de anticoagulantes orais a serem submetidas a tratamento odontológico é crescente e o manejo desses indivíduos requer criteriosa avaliação da condição clínica e do procedimento a ser realizado. Objetivo Avaliar o nível de conhecimento de cirurgiões-dentistas e graduandos em Odontologia quanto ao manejo de indivíduos em uso de anticoagulantes orais a serem submetidos a tratamento odontológico. Material e método Investigação descritiva, quantitativa, de corte transversal, com base em um questionário respondido por 100 indivíduos, sendo 70 cirurgiões-dentistas e 30 graduandos do curso de Odontologia, escolhidos por conveniência, para avaliar o conhecimento sobre o tema proposto. Para comparação das variáveis quantitativas, foi utilizado o Teste t de student, para comparação de duas amostras, e o Teste ANOVA, com pós-teste de Bonferroni, para comparação de três amostras. Resultado Dentre os entrevistados, 74,5% dos cirurgiões-dentistas e 54,2% dos graduandos relataram já ter atendido um paciente que faz uso de anticoagulante oral. Não houve diferença estatística quanto ao desempenho entre profissionais e alunos acerca do manejo odontológico de pacientes em uso de anticoagulantes. Dentre o grupo de cirurgiões-dentistas, os profissionais da cirurgia bucomaxilofacial e os que fizeram residência multiprofissional apresentaram melhor desempenho quando comparados aos clínicos gerais. Conclusão Pôde-se concluir que, para os grupos estudados, o manejo de pessoas em uso de anticoagulantes orais ainda é um desafio.

Abstract Introduction Cardiovascular diseases have a high incidence and due to that there is a large amount of patients who take medications for prevention and treatment of these disorders. Consequently, the number of people to be submitted to dental treatment and also under oral anticoagulant therapy is increasing and the management of these individuals requires a careful evaluation of the clinical condition and the procedure to be performed. Objective To evaluate the level of knowledge of dentists and undergraduate dental students in the management of individuals using oral anticoagulants to be submitted to dental treatment. Material and method Descriptive, quantitative, cross-sectional study based on a questionnaire answered by 100 individuals (70 dentists and 30 undergraduate dental students), chosen for convenience to evaluate their knowledge about the proposed topic. To compare the quantitative variables, the Student's T test was used to compare two samples and the ANOVA test with Bonferroni's post test to compare three samples. Result Among the interviewees, 74.5% of dental surgeons and 54.2% of undergraduates reported having attended a patient under oral anticoagulant therapy. There was no statistical difference regarding the performance between professionals and students in the dental management of patients taking anticoagulants. Among the group of dental surgeons, the professionals of the bucomaxillofacial surgery and those who had multiprofessional residency presented better performance when compared to the general practitioners. Conclusion The management of patients using oral anticoagulants stills a challenge for the groups studied.

Introduction  The nonsyndromic orofacial cleft is the fourth most common birth defect, but in Brazil, data about the cleft epidemiology are not accurate. Objective  This study aimed to describe the epidemiologic characteristics of oral cleft cases at Specialized Society Attending Cleft Patient in Sergipe State. Methods  Data were obtained from patients' medical records in relation to the following characteristics: age; gender; race; origin; cleft type; additional malformations and/or complications; prenatal accomplishment; treatment applied. For diagnosis analysis, it was noted if mothers had received prenatal care and if they had ultrasonography performed and if the cleft was viewed in it. Results  We observed a prevalence of male gender (54%). Age between 0 and 4 years old was most prevalent (53%), and pheoderma race was observed in 47%. Transincisive foramen cleft was found in 52.3% of the individuals. The prevalence of pre- and transincisive foramen cleft was higher in men (66.3 and 55.7%), women accounted for 65.0% of postincisive foramen, and atypical facial cleft (0.3%) occurred in one case. Associated malformations and complications were present in 12% of patients. Prenatal care was reported by 48% of the mothers. Conclusion  In this study male gender was the most affected, and 0 to 4 years was the most frequent age group. Transincisive foramen cleft type was most frequently encountered. Prenatal care was reported by most mothers. So, this study found that early treatment is a reality in SEAFESE (Service Specializing in Cleft Care of Sergipe), and consequently the chances of successful integration of the child to society will be better.

OBJETIVO: avaliar, por meio da mastigação sequencial de uma "pastilha" artificial de Optosil, o desempenho mastigatório de indivíduos respiradores nasais e orais. MÉTODO: participaram sessenta sujeitos dentados na faixa etária de 14 a 22 anos. Uma "pastilha" de Optosil foi fornecida a cada participante, que executou 20 ciclos mastigatórios, os fragmentos foram colocados numa coluna de sete peneiras, sendo, posteriormente pesados numa balança de precisão. Os dados obtidos foram submetidos à análise descritiva e inferencial (Teste T e ANOVA). RESULTADOS: os grupos respiradores nasais e respiradores orais foram constituídos de 30 jovens cada, com idade média de 17,87 e 17,83 anos respectivamente. Com relação ao gênero houve predominância do gênero feminino no grupo respirador oral e do gênero masculino no grupo respirador nasal Os cinco diagnósticos mais prevalentes no grupo respirador oral foram hipertrofia de adenóide, rinite alérgica, sinusite, asma e hipertrofia de amígdala. Por fim, ao ser realizado o Teste T, não foi encontrada diferença estatística na performance mastigatória nos respiradores orais e nasais (p>0,05). CONCLUSÃO: o padrão respiratório não foi um fator determinante na performance mastigatória.

PURPOSE: the purpose is to evaluate, through the chewing sequence of an Optosil artificial "tablet", the masticatory performance in nasal breathing and mouth breathing. METHOD: we attended sixty dentate subjects aged 14-22 year old. An Optosil "tablet" was supplied to each participant, who executed 20 masticatory cycles, the Optosil fragments had been placed in a column with seven bolters, and the retained particles were weighed on a precision analytical balance and the masticatory efficiency value was calculated. The gotten data were submitted to the descriptive analysis and inferential analysis (test T and ANOVA). RESULTS: the nasal breathing and mouth breathing groups were composed by 30 young people each, with a mean age of 17.87 and 17.83 year old, respectively. Regarding gender, the females predominated in the mouth breathing group and the males in the nasal breathing group. The five most prevalent diagnoses in the mouth breathing group were adenoid hypertrophy, allergic rhinitis, sinusitis, asthma and tonsillar hypertrophy. Finally, when we carried out the t test, there was no statistical difference in masticatory performance in mouth breathing and nasal breathing (p> 0.05). CONCLUSION: it was concluded that the breathing pattern was not a determining factor in the masticatory efficiency.