RESUMO Objetivo Escalas de avaliação prognóstica do acidente vascular cerebral isquêmico (AVCI) podem ajudar decisões clinicas. O objetivo deste estudo foi avaliar o desempenho de quatro escalas prognósticas em uma população brasileira. Método Foram avaliados os dados de pacientes admitidos com AVCI no Hospital Paulistano, um hospital acreditado pela “Joint Commission International”. A mortalidade intra-hospitalar e a escala de Rankin foram definidos como desfechos de evolução clínica. O desempenho de quatro escalas: National Institutes of Health Stroke Scale (NIHSS), Stroke Prognostication Using Age and NIHSS (SPAN-100), Acute Stroke Registry and Analysis of Lausanne (ASTRAL) e Totaled Health Risks in Vascular Events (THRIVE) foi comparado. Resultados Foram incluídos duzentos e seis pacientes, com uma idade média de 67,58 ± 15,5 anos, sendo 55,3% dos sexo masculino. Todas as quatro escalas associaram-se de forma independente com prognóstico funcional. Apenas o THRIVE correlacionou-se com a mortalidade hospitalar. O THRIVE e o NIHSS tiveram melhor desempenho para prognóstico funcional e o THRIVE teve o melhor desempenho para mortalidade pela área sob a curva. Conclusão O THRIVE mostrou-se a escala com melhor performance, sendo a única correlacionada com a mortalidade hospitalar.

ABSTRACT Objective Ischemic stroke (IS) prognostic scales may help clinicians in their clinical decisions. This study aimed to assess the performance of four IS prognostic scales in a Brazilian population. Method We evaluated data of IS patients admitted at Hospital Paulistano, a Joint Commission International certified primary stroke center. In-hospital mortality and modified Rankin score at discharge were defined as the outcome measures. The performance of National Institutes of Health Stroke Scale (NIHSS), Stroke Prognostication Using Age and NIHSS (SPAN-100), Acute Stroke Registry and Analysis of Lausanne (ASTRAL), and Totaled Health Risks in Vascular Events (THRIVE) were compared. Results Two hundred six patients with a mean ± SD age of 67.58 ± 15.5 years, being 55.3% male, were included. The four scales were significantly and independently associated functional outcome. Only THRIVE was associated with in-hospital mortality. With area under the curve THRIVE and NIHSS were the scales with better performance for functional outcome and THRIVE had the best performance for mortality. Conclusion THRIVE showed the best performance among the four scales, being the only associated with in-hospital mortality.

Peumus boldus, an endemic tree species of central Chile, belongs to sclerophyllous forests. Its semi-xerophytes condition allows it to grow in places with low rainfall and poor soils. The current shrubby condition is due to the implemented management through a coppice regime. This management was proposed due to its low ability for seed regeneration and its high ability to sprout. Currently, the harvest of this species is mainly based on economic criteria, with a lacking of productivity and technical criteria to define its silviculture. It is essential to understand the response of sprouts after interventions to improve its management. The aim of this study was to evaluate the response during the first two years of P. boldus coppices with different cutting intensities. A set of 23 strains was annually monitored in three levels of intervention: total, partial (50 % basal area) and without stools cuts (control). Predawn water potential, chlorophyll fluorescence, diameter growth and above-ground biomass accumulation were evaluated. Results showed that cuts improved the hydric status and this status was directly related to the cutting intensity of the strains. The same effect was observed in the production and growth of new shoots. Finalizing the evaluation period, accumulated biomass was 17.9 % in strains with total harvest and 53.6 % in those with partial harvest. These results raise doubts over the ability of P. boldus to correctly recover after biomass harvesting in short management periods. These results show that strains of P. boldus can be utilized in a better way with partial harvest. Further studies are needed to determine intensity and frequency of harvest.

Peumus boldus, especie arbórea endémica de Chile central del bosque esclerófilo, por su condición semi-xerófita se desarrolla con bajas precipitaciones y suelos pobres. Actualmente presenta estado arbustivo, debido a manejo de monte bajo por su alta capacidad de rebrote y baja regeneración por semilla. La cosecha de P. boldus se basa principalmente en criterios económicos, faltando criterios productivos y técnicos para definir su silvicultura. Para mejorar el manejo actual, es fundamental comprender la respuesta del rebrote después de la cosecha. El objetivo del estudio fue evaluar la respuesta de cepas de P. boldus sometidas a diferentes intensidades de cosecha, durante los dos primeros años después de la corta, para establecer pautas de manejo silvicultural de la especie. Para ello se monitoreó anualmente un grupo de 23 cepas con tres niveles de cosecha: total, parcial (50 % del área basal) y sin intervención (control). Se evaluaron las respuestas: hídrica, proceso fotosintético mediante fluorescencia, crecimiento en diámetro y acumulación de biomasa aérea. Los resultados mostraron que las cortas mejoraron el estado hídrico de las cepas en relación directa a la intensidad aplicada, además de incrementar la aparición y crecimiento de nuevos rebrotes. Al final del segundo año de evaluación, la biomasa acumulada fue del 17,9 % de la biomasa inicial en las cepas con cosecha total, y del 53,6 % en las con cosecha parcial. Estos resultados muestran que cepas de P. boldus pueden ser manejadas de mejor forma, con una cosecha parcial. Nuevos estudios son necesarios para determinar la intensidad y periodicidad de la cosecha.