Feeding with high levels of phytochemicals, including curcumin, may be a therapeutic option for diseases such as cancer which is a public health problem. The aim of this study was to systematically review the results of clinical trials investigating the effect of oral curcumin supplementation on anti-inflammatory and antioxidant profiles, reduction of PSA levels and degree of dermatitis in radiotherapy treatment in cancer patients. The review was carried out based on the items of the PRISMA Statement. A bias risk assessment was performed according to Cochrane Collaboration criteria. Six studies met the eligibility criteria and were included in the systematic review. The results of this study are based on those obtained in the literature on the effect of curcumin on the anti-inflammatory profile, on reducing dermatitis, on PSA alteration and on anti-oxidant profile for a total of 450 individuals, comprising 259 in the intervention group and 191 in the control group. Some studies have reported improvement in biochemical and clinical indicators, with limited adverse effects and good tolerance. It was not possible to determine, with the desired degree of evidence, the effect of curcumin supplementation in the treatment of cancer patients. It is important to consider the great heterogeneity and methodological weaknesses of the studies, and that it was not possible to perform a meta-analysis of the data available in the literature.

Resumo Objetivos: Determinar a prevalência das lesões associadas aos ossos maxilares biopsiadas em pacientes atendidos pelo Centro de Referência de Lesões Bucais (CRLB) da Universidade Estadual de Feira de Santana (UEFS) no período de 2006 a 2017, identificando as três lesões mais frequentes e suas características clínicas. Métodos: Estudo transversal, descritivo, realizado ao avaliar todos as laudos histopatológicos dos últimos 11 anos, que tiveram como diagnóstico histopatológico alguma das lesões associadas aos ossos maxilares preconizadas pela OMS (2017) e dados sobre os pacientes, como: género, idade, diagnóstico histopatológico e localização anatómica. As informações coletadas foram transpostas para tabelas através do Software Microsoft Office Excel Professional Plus (2013). Resultados: Foram encontrados 65 laudos conclusivos para lesões associadas aos ossos maxilares, com prevalência de 0,03. Os pacientes tiveram idade média de 45,2 anos, geralmente do género feminino e a região posterior da mandíbula como a mais acometida. Conclusões: As lesões mais frequentes foram a displasia cemento-óssea, displasia fibrosa e fibroma ossificante.

Abstract Objectives: To determine the prevalence of lesions associated with the maxillary bone biopsied from patients assisted at the Reference Centre for Oral Injuries of the State University of Feira de Santana (CRLB - UEFS) from 2006 to 2017, identifying the three most frequent lesions and their clinical characteristics. Methods: A descriptive, cross-sectional study was carried out to evaluate all the histopathological reports of the last 11 years that included a histopathological diagnosis of bone lesions of the maxilla preconized by the WHO (2017), as well as data on patients, such as gender, age, histopathological diagnosis, and anatomical location. The collected information was input into tables using Microsoft Office Excel Professional Plus Software (2013). Results: 65 conclusive reports were found for bone lesions of the maxilla, with a prevalence of 0.03. The mean age was 45.2 years, and the female gender and the posterior region of the mandible were the most affected. Conclusions: The most frequent lesions were cemento-osseous dysplasia, fibrous dysplasia, and ossifying fibroma.

Considering the current global situation, marked by important public health crises and, more recently, the pandemic caused by COVID-19, this article aimed to gather information and research findings on the impact of such crises on mental health. The text presents main concepts related to the new coronavirus and analyzes consequences of measures adopted to deal with scenarios such as the current problem, which involve social distance, quarantine, and isolation, throughout three distinct moments: pre-crisis, intracrisis, and post-crisis. The paper focuses on the repercussions observed on the population's mental health and discusses favorable and unfavorable outcomes within the crisis process. It is finished presenting questions related to the emergence of mental health care provided by Psychology and other health professionals, aiming to reduce negative impacts of this crisis and act in a preventive function.

Considerando-se a situação atual mundial, marcada por importantes crises na saúde pública e, mais recentemente, a pandemia causada pela COVID-19, o presente artigo buscou reunir informações e achados de pesquisa a respeito do impacto de tais crises na saúde mental. O texto traz conceitos relacionados à problemática do novo coronavírus e analisa consequências de medidas adotadas para lidar com situações desse tipo, tais como distanciamento social, quarentena e isolamento, ao longo de três períodos distintos: pré-crise, intracrise e pós-crise. O artigo enfoca as repercussões observadas na saúde mental da população, refletindo acerca dos desfechos favoráveis e desfavoráveis dentro do processo de crise. Por fim, são apresentadas questões relacionadas a emergência do cuidado em saúde mental, tanto aquele prestado pela Psicologia, como aquele que pode ser desenvolvido pelos demais profissionais de saúde, de modo a minimizar os impactos negativos da crise e atuar de modo preventivo.

Resumo Considerando-se a situação atual mundial, marcada por importantes crises na saúde pública e, mais recentemente, a pandemia causada pela COVID-19, o presente artigo buscou reunir informações e achados de pesquisa a respeito do impacto de tais crises na saúde mental. O texto traz conceitos relacionados à problemática do novo coronavírus e analisa consequências de medidas adotadas para lidar com situações desse tipo, tais como distanciamento social, quarentena e isolamento, ao longo de três períodos distintos: pré-crise, intracrise e pós-crise. O artigo enfoca as repercussões observadas na saúde mental da população, refletindo acerca dos desfechos favoráveis e desfavoráveis dentro do processo de crise. Por fim, são apresentadas questões relacionadas à emergência do cuidado em saúde mental, tanto aquele prestado pela Psicologia, como aquele que pode ser desenvolvido pelos demais profissionais de saúde, de modo a minimizar os impactos negativos da crise e atuar de modo preventivo.

Abstract Considering the current global situation, marked by important public health crises and, more recently, the COVID-19 pandemic, this article aims to gather information and research findings on the impact of such crises on mental health. The text presents the main concepts related to the new coronavirus and analyzes the consequences of the measures adopted to deal with scenarios such as the current problem, which involve social distance, quarantine, and isolation, within three distinct moments: pre-crisis, intra-crisis, and post-crisis. The paper focuses on the repercussions observed on the population's mental health and discusses favorable and unfavorable outcomes within the crisis process. To conclude, it presents questions related to the emergence of mental health care provided by Psychology and other health professionals in order to reduce negative impacts of this crisis and act in a preventive function.

Resumo Fundamentos: Com a criação do SUS, todos teriam acesso universal, integral e equânime à assistência de saúde de qualidade. Entretanto, existe grande lacuna de estudos escrutinizando o SUS no tocante à qualidade assistencial praticada. Esse fato é especialmente crítico para vítimas de infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAMCSST), sendo a responsividade do sistema e o uso da reperfusão em tempo hábil fatores cardinais para obtenção de melhores resultados. Objetivo: Descrever a metodologia empregada no Registro VICTIM que tem como objetivo caracterizar e comparar o acesso e o uso de terapias efetivas e desfechos entre os pacientes com IAMCSST usuários do SUS e do sistema privado atendidos nos hospitais com capacidade de realizar angioplastia em Sergipe, tentanto identificar e mensurar eventuais disparidades na qualidade da assistência. Métodos e Resultados: O Registro VICTIM é um estudo observacional, iniciado em dezembro de 2014, e ainda em fase de coleta, com a intenção de investigar a epidemiologia do IAMCSST em Sergipe, os cursos temporal e geográfico dos pacientes até sua admissão em uma instituição com capacidade de realizar angioplastia, uso de terapias de reperfusão, qualidade assistencial recebida durante a linha de cuidado, bem como a mortalidade de 30 dias, comparando-se os resultados obtidos pela população usuária do SUS e do sistema privado. Conclusões: O registro VICTIM é um esforço interinstitucional para identificar oportunidades de melhoria na linha de cuidado para IAMCSST de usuários do SUS e do sistema privado. Com isso, espera-se municiar os gestores públicos de informações técnicas que embasem novas políticas de saúde mais eficientes e equânimes.

Abstract Background: The Brazilian Unified Health System (SUS) was created to ensure universal, integral and equitable access to quality healthcare to Brazilians. However, studies scrutinizing the quality of the healthcare provided by the SUS are scarce. This is especially critical for patients with ST-elevation myocardial infarction (STEMI), who depend on healthcare system responsiveness and timely reperfusion to achieve better outcomes. Objective: To describe the methodology of the VICTIM Registry aimed at characterizing and comparing the access to effective therapies and the outcomes of patients with STEMI, who use the SUS and the private healthcare system at hospitals capable of performing angioplasty in Sergipe. In addition, that registry aimed at identifying and measuring possible disparities in the quality of the care provided. Methods and Results: The VICTIM Registry is an observational study, launched in December 2014, being still in the data collection phase, to investigate: the epidemiology of STEMI in Sergipe, the temporal and geographic courses of the patients up to their admission to one of the hospitals capable of performing angioplasty, the reperfusion therapy rates, the quality of the healthcare provided during the event, and the 30-day mortality. It compares the results obtained in the SUS with those of the private healthcare system. Conclusions: The VICTIM Registry is an interinstitutional effort to identify opportunities for healthcare improvement for SUS and private healthcare system patients with STEMI. It is expected to provide healthcare managers with information to support new, more efficient and equitable healthcare policies.

ABSTRACT: In common bean (Phaseolus vulgaris) harvesting is carried out in the field. It is therefore necessary that cultivars be tolerant to viviparity, i.e., germination of grains still in the pods. Study of the percentage of germination of beans in the pods under laboratory conditions, where humidity content is high, has been proposed. Furthermore, under question is whether the thickness of the pod wall affects water uptake by the pods and, consequently, viviparity. Thus, the aim of the present study was to verify if there is variance among progenies for viviparity and if it is influenced by pod thickness. We assessed the parents, Pérola and ESAL 686, the F1, and a number of segregating generations in two crop seasons, in relation to the percentage of germination of seeds in the pods (PGSP) and pod wall thickness (PWT), and data on individual plants were obtained. The same traits were also assessed using the F2:3, F3:4 and F4:5 progenies. Taking into account the genetic and phenotypic parameters estimates, especially the level of high heritability, selection to less viviparity in common bean has to be carried out to evaluate PGSP in progenies.

A incorporação de resistência genética a doenças e o aumento na produtividade de grãos estão entre os principais objetivos dos programas de desenvolvimento de híbridos. A identificação de locos de caracteres quantitativos (QTL) por meio de análises estatísticas associadas a marcadores moleculares possibilita a rápida obtenção de híbridos resistentes e produtivos. Nesta pesquisa, objetivou-se identificar locos de caracteres quantitativos (QTL) associados com resistência à cercosporiose e com produção de grãos em germoplasma de milho tropical. Foram utilizadas duas linhagens contrastantes em níveis de reação à doença (genótipos pertencentes à GENESEEDS - Ltda), seu híbrido F1 e a população segregante F2. Essas plantas foram fenotipadas quanto à resistência a doença e quanto a produção de grãos e genotipadas com 94 marcadores de microssatélites. A associação dos marcadores ao QTL foi realizada por meio de análises de marcas individuais, utilizando as metodologias de regressão linear e análise da máxima verossimilhança. Observou-se que o tipo de efeito predominante no controle genético da resistência a cercosporiose foi o aditivo e para o controle genético da produção de grãos foi de dominância. Os marcadores microssatélites mais promissores para serem utilizados em estudos de seleção assistida para resistência a cercosporiose são umc2082 na posição 4.03 e umc1117 na posição 4.04 e para produção de grãos, umc1042 e umc1058 nas posições 2.07 e 4.11.

The main objectives of hybrid development programs include incorporating genetic resistance to diseases and increasing grain yield. Identification of Quantitative Trait Loci (QTL) through the statistical analysis of molecular markers allows efficient selection of resistant and productive hybrids. The objective of this research was to identify QTL associated with resistance to gray leaf spot and for grain yield in the germplasm of tropical corn. We used two strains with different degrees of reaction to the disease; the genotypes are owned by GENESEEDS Ltda, their F1 hybrid and the F2 population. The plants were evaluated for gray leaf spot resistance, for grain yield and were genotyped with 94 microsatellite markers. Association of the markers with the QTL was performed by single marker analysis using linear regression and maximum likelihood analysis. It was observed that the additive effect was predominant for genetic control of resistance to gray leaf spot, and the dominant effect in that of grain yield. The most promising markers to be used in studies of assisted selection are: umc2082 in bins 4.03 and umc1117 in bins 4.04 for resistance to gray leaf spot; for grain yield umc1042 in bins 2.07 and umc1058 in bins 4.11.