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OCCULT AND SEMI-OCCULT CONSTIPATION IN CHILDREN WITH MONOSYMPTOMATIC OR NON MONOSYMPTOMATIC ENURESIS
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MAFFEI, Helga Verena L

; VIDOLIN, Eliana

; REIS, Joceara Neves dos

; FREITAS, Marcia de

; CABRAL, Beatriz Helena

; TRIGO-ROCHA, Flavio

Arquivos de Gastroenterologia

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nov 2023, Volume 60 N. 4 Pages 410 - 418

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Background: Functional constipation and enuresis frequently coexist. Constipation treatment often results in resolution or improvement of the enuresis. However, besides the classical presentation, patients can present with occult constipation (OC) diagnosed in complementary evaluation; in addition, semi-occult constipation (SOC) can be detected by means of a detailed questionnaire. Objective: To quantify OC and SOC frequency in children with monosymptomatic or non monosymptomatic enuresis (MNE or NMNE). Methods: Otherwise healthy children/adolescents, with enuresis refractory to behavioral therapy and denying constipation after simple questions, answered a structured bowel habit questionnaire and were submitted to a plain abdominal radiological exam. Constipation was classified considering the Boston diagnostic criteria (to allow diagnosis at initial stages), and fecal loading in the X-ray quantified ≥10 by the Barr score. Children with constipation received a standardized treatment (except 26 “pilot” children). Results: Out of 81 children, 80 aged 9.34±2.07 years, 52.5% male, were diagnosed with constipation: 30 OC, 50 SOC; 63.75% had MNE, 36.25% NMNE (six NMNE without behavioral therapy). Demographic data and the Barr score were similar for OC and SOC, but SOC children experienced significantly more constipation complications (retentive fecal incontinence and/or recurrent abdominal pain). Not showing the Bristol Stool Scale (BSS) to 24 “pilot” children, or absence of constipation symptoms accompanying BSS predominantly type 3, in 13 children, did not significantly impact the detection of constipation by the Barr score. Children identifying BSS 3 or ≤2 had similar results. Twenty-eight children, with adequate follow-up after treatment, improved or recovered from constipation at 44 of their 52 follow-up visits. Conclusion: In patients with MNE or NMNE refractory to behavioral therapy, and who initially denied constipation after simple questions, a detailed questionnaire based on the Boston diagnostic criteria detected SOC in 61.7%, and the radiological Barr score revealed fecal loading (OC) in 37.0% of them.

RESUMO Contexto: Constipação funcional e enurese frequentemente coexistem. Tratamento da constipação geralmente resulta em cura ou melhora da enurese. Entretanto, além da apresentação clássica, pode ocorrer constipação oculta (CO), diagnosticada por exame subsidiário; ademais, ao aplicar questionário detalhado, pode-se detectar constipação semioculta (CSO). Objetivo: Obter as frequências de CO e CSO em crianças com enurese mono- ou não monossintomática (EMN ou ENMN). Métodos: Crianças/adolescentes saudáveis, exceto por enurese refratária à terapia comportamental, e que negavam constipação após perguntas simples, respondiam a questionário estruturado sobre hábito intestinal, e realizavam radiografia simples de abdômen. A constipação foi classificada considerando os critérios diagnósticos de Boston (que permitem diagnóstico em fases iniciais) e retenção fecal na radiografia quantificada ≥10 pelo escore de Barr. As crianças com constipação receberam tratamento padronizado (exceto 26 crianças “piloto”). Resultados: Das 81 crianças, 80 com idade 9,34±2,07 anos, 52,5% masculinas, foram diagnosticadas com constipação: 30 CO, 50 CSO; 63.75% tinham EMN, 36.25% ENMN (6 ENMN sem terapia comportamental). Os dados demográficos e o escore de Barr foram semelhantes para CO e CSO, mas as crianças com CSO apresentaram significativamente mais complicações de constipação (incontinência fecal retentiva e/ou dor abdominal recorrente). A não apresentação da Escala Fecal de Bristol (EFB) para 24 crianças “piloto”, ou ausência de sintomas de constipação acompanhando EFB predominantemente do tipo 3, em 13 crianças, não teve impacto significativo na detecção de constipação pelo escore de Barr. Crianças que identificaram EFB 3 ou ≤2 tiveram resultados semelhantes. Vinte e oito crianças, com acompanhamento adequado após o tratamento, melhoraram ou se recuperaram da constipação em 44 de seus 52 retornos. Conclusão: Em pacientes com EMN ou ENMN refratária à terapia comportamental, e que inicialmente negavam constipação após perguntas simples, questionário baseado nos critérios diagnósticos de Boston detectou CSO em 61.7%, e o escore radiológico de Barr revelou retenção fecal (CO) em 37% deles.

https://doi.org/10.1590/s0004-2803.230402023-07

A percepção sobre meio ambiente e Educação Ambiental na prática docente das professoras das escolas municipais rurais de Morrinhos, GO Morrinhos
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Santos, Flávio Reis

; Cândido, Cristiane Raquel Ferreira

Interações (Campo Grande)

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mar 2023, Volume 24 N. 1 Pages 175 - 191

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

Resumo O presente estudo teve o objetivo de analisar a percepção de professoras da Educação Infantil e do Ensino Fundamental I das escolas municipais rurais de Morrinhos, GO, sobre o Meio Ambiente e a Educação Ambiental, a saber: Escola Municipal Vereador Deusdete Damacena, Escola Municipal Lindolfo Alves Pinto e Escola Municipal José Cândido da Silva. Por ser uma pesquisa que envolve a percepção do sujeito, optamos pelo estudo de caso com o emprego de uma abordagem qualitativa para análise dos dados. Em todas as escolas, foram aplicados questionários com perguntas semiestruturadas para as sete professoras participantes da pesquisa, relacionadas às questões ambientais. Esclarecemos que este estudo decorre de nossa inquietação em repensar a relação do homem com a natureza, bem como das concepções de desenvolvimento, progresso e crescimento impostas pelo modelo econômico capitalista e a forma como a Educação Ambiental (EA) está sendo trabalhada nas escolas rurais. Os resultados mais importantes apontam que a escola é um dos principais locais para promover mudanças de comportamento ao trabalhar com os diversos saberes ambientais; porém, muitos desafios no trabalho com a EA ainda precisam ser superados, a começar pela formação dos professores. A maior parte dos sujeitos da pesquisa ainda tem uma visão reducionista, naturalizada e antropocêntrica, tanto em relação ao meio ambiente quanto em relação à EA. Morrinhos GO saber Damacena Silva sujeito dados ambientais natureza desenvolvimento (EA porém superados professores reducionista antropocêntrica

Resumen El presente estudio tuvo como objetivo analizar la percepción de los docentes de Educación Infantil y Primaria de las escuelas municipales rurales de Morrinhos, GO, sobre el Medio Ambiente y Educación Ambiental, a saber: Escuela Municipal Vereador Deusdete Damacena, Escuela Municipal Lindolfo Alves Pinto y Escuela Municipal José Cândido da Silva. Al ser una investigación que involucra la percepción del sujeto, optamos por el estudio de caso con el uso de un enfoque cualitativo para el análisis de datos. En todas las escuelas se aplicaron cuestionarios con preguntas semiestructuradas a los siete docentes participantes en la investigación, relacionados con temas ambientales. Aclaramos que este estudio surge de nuestra preocupación por repensar la relación entre el hombre y la naturaleza, así como las concepciones de desarrollo, progreso y crecimiento que impone el modelo económico capitalista y la forma en que se trabaja la Educación Ambiental (EA) en escuelas rurales. Los resultados más importantes muestran que la escuela es uno de los principales lugares para promover cambios de comportamiento cuando se trabaja con diferentes conocimientos ambientales, sin embargo, aún quedan por superar muchos desafíos en el trabajo con EA, comenzando por la formación docente. La mayoría de los sujetos de investigación aún tienen una visión reduccionista, naturalizada y antropocéntrica, tanto en relación al medio ambiente como en relación a la EA. Morrinhos GO saber Damacena Silva sujeto datos ambientales naturaleza desarrollo EA (EA embargo docente reduccionista antropocéntrica

Abstract The present study aimed to analyze the perception of teachers of Kindergarten and Elementary School of rural municipal schools in Morrinhos, GO, about the Environment and Environmental Education, namely: Municipal School Vereador Deusdete Damacena, Municipal School Lindolfo Alves Pinto, and Municipal School José Cândido da Silva. As it is a research that involves the subject’s perception, we opted for the case study with the use of a qualitative approach for data analysis. In all schools, questionnaires with semi-structured questions were applied to the seven teachers participating in the research, related to environmental issues. We clarify that this study stems from our concern to rethink the relationship between man and nature, as well as the conceptions of development, progress, and growth imposed by the capitalist economic model and how Environmental Education (EE) is being worked on in rural schools. The most important results show that the school is one of the main places to promote changes in behavior when working with different environmental knowledge; however, many challenges in working with EE still need to be overcome, starting with teacher training. Most of the research subjects still have a reductionist, naturalized, and anthropocentric view, both concerning the environment and Environmental Education. Morrinhos GO namely Damacena Pinto Silva subject s analysis semistructured semi structured issues nature development progress (EE knowledge however overcome training reductionist naturalized view

https://doi.org/10.20435/inter.v24i1.3476

Update of the Brazilian consensus recommendations on Duchenne muscular dystrophy
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Araujo, Alexandra Prufer de Queiroz Campos

; Saute, Jonas Alex Morales

; Fortes, Clarisse Pereira Dias Drumond

; França Jr, Marcondes Cavalcante

; Pereira, Jaqueline Almeida

; Albuquerque, Marco Antonio Veloso de

; Carvalho, Alzira Alves de Siqueira

; Cavalcanti, Eduardo Boiteux Uchôa

; Covaleski, Anna Paula Paranhos Miranda

; Fagondes, Simone Chaves

; Gurgel-Giannetti, Juliana

; Gonçalves, Marcus Vinicius Magno

; Martinez, Alberto Rolim Muro

; Coimbra Neto, Antônio Rodrigues

; Neves, Flavio Reis

; Nucci, Anamarli

; Nucera, Ana Paula Cassetta dos Santos

; Pessoa, Andre Luis Santos

; Rebel, Marcos Ferreira

; Santos, Flavia Nardes dos

; Scola, Rosana Herminia

; Sobreira, Cláudia Ferreira da Rosa

Arquivos de Neuro-Psiquiatria

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jan 2023, Volume 81 N. 1 Pages 81 - 94

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract In the last few decades, there have been considerable improvements in the diagnosis and care of Duchenne muscular dystrophy (DMD), the most common childhood muscular dystrophy. International guidelines have been published and recently reviewed. A group of Brazilian experts has developed a standard of care based on a literature review with evidence-based graded recommendations in a two-part publication. Implementing best practice management has helped change the natural history of this chronic progressive disorder, in which the life expectancy for children of the male sex in the past used to be very limited. Since the previous publication, diagnosis, steroid treatment, rehabilitation, and systemic care have gained more significant insights with new original work in certain fields. Furthermore, the development of new drugs is ongoing, and some interventions have been approved for use in certain countries. Therefore, we have identified the need to review the previous care recommendations for Brazilian patients with DMD. Our objective was to create an evidence-based document that is an update on our previous consensus on those topics.

Resumo Nas últimas décadas, houve progressos significativos no diagnóstico e no tratamento da distrofia muscular de Duchenne (DMD), considerada a distrofia muscular mais comum na infância. Diretrizes internacionais foram publicadas e revisadas recentemente. Um grupo de especialistas brasileiros desenvolveu um padrão de atendimento baseado em revisão de literatura, com recomendações graduadas pautadas em evidências compiladas em uma publicação dividida em duas partes. A implementação de melhores práticas de manejo ajudou a modificar a história natural desta doença crônica, progressiva, que, no passado, oferecia uma expectativa de vida muito limitada para crianças do sexo masculino. Desde a publicação desse consenso anterior, o diagnóstico, o tratamento com esteroides, a reabilitação e os cuidados sistêmicos ganharam novas possibilidades a partir da divulgação dos resultados de trabalhos originais em algumas dessas áreas. Além disso, as pesquisas e o desenvolvimento de novos fármacos estão em andamento, e algumas intervenções já foram aprovadas para uso em determinados países. Nesse contexto, identificamos a necessidade de rever as recomendações anteriores sobre o manejo dos pacientes brasileiros com DMD. Nosso objetivo principal foi elaborar uma atualização baseada em evidências sobre esses tópicos do consenso.

https://doi.org/10.1055/s-0043-1761466

The management of phosphate fertilization affects soil phosphorus and yield of autumn/winter crops
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Macedo, Júlia Rodrigues

; Moreira, Silvino Guimarães

; Moraes, Flávio Araújo de

; Reis Junior, Daniel de Souza

; Peixoto, Devison Souza

; Silva, Bruno Montoani

; Silva, Júnior Cézar Resende

Acta Scientiarum. Agronomy

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2023, Volume 45 elocation e57336

Abstract: En | Text: En | PDF: En

ABSTRACT. In soils with adequate levels of fertility, it is possible to manage phosphate fertilization aiming at the grain production system, instead of each isolated crop. The objective was to evaluate the effects of the management of phosphate fertilization, place and time, on the soil and leaf P content, and crop yield in grain production systems. An experiment was conducted at the farm level in the municipality of Nazareno, state of Minas Gerais, Brazil, for four years on soil with adequate level of fertility. The treatments consisted of the management of phosphate fertilization by broadcast or furrow and dose for each crop or for the production system (spring/summer and autumn/winter crops), being: Control = without phosphate fertilization; Conventional = phosphate fertilization in the furrow in each crop; BTP = phosphate fertilization of the grain production system to broadcast; TPS = phosphate fertilization of the grain production system in the furrow of the spring/summer crop; TPW = phosphate fertilization of the grain production system in the furrow of the autumn/winter crop. Soil P content was evaluated in the third year of implantation, and the crops yield every season crop (maize, soybean, common bean and wheat). The P content in the leaves of maize and soybeans were evaluated in the spring/summer crops. The application of the total dose of phosphate fertilization for both crops in the sowing furrow of the spring/summer or autumn/winter crops (TPS and TPW) promoted operational advantages and increased soil P content in the 0-0.20 m layer, without reducing the yield of the spring/summer crops. Leaf P content was not affected. The Conventional management (phosphate fertilization in the furrow in each crop) provide greater yield of common beans and wheat during autumn/winter crops, which are more subject to water restriction due to less rainfall, even without increasing the soil P content.

https://doi.org/10.4025/actasciagron.v45i1.57336

Linear and undulating resistance training programming induce similar outcomes on physical fitness in elderly women
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Silva, Surama do Carmo Souza da

; Pires, Flavio de Oliveira

; Batista Junior, Marifran Tomé

; Serra, Larissa de Lourdes Padilha

; Reis, Carlos Brendo Ferreira

; Abreu, Leudyenne Pacheco de

; Pereira, Paula Tâmara Vieira Teixeira

; Cabido, Christian Emmanuel Torres

; Leite, Richard Diego

Revista Brasileira de Cineantropometria & Desempenho Humano

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2023, Volume 25 elocation e77528

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The aim of the present study was to analyze the effect of two different types of resistance training programming (linear and daily undulating) on submaximal strength and functional capacity in elderly women. Twenty-two participants (64 ± 3 years) were randomly assigned to 2 training groups: linear programming (LP; n=12) and daily undulating programming (DUP; n =10). Functional capacity and submaximal strength (10RM) were analyzed before and after 12 weeks of resistance training. The results demonstrated improvement on strength and functional capacity after the resistance training period (p ≤ 0.05), except for the Bench Press (p = 0.30), for both groups DUP and LP. The Effect Size was, respectively, high for DUP (timed up and go test = -2.07, and timed sit test= 4.69), and high for LP (horizontal leg press = 2.35). For all other results, the effect size was trivial or small. No statistical difference was observed between programming models. The LP and DUP trainnings have similar results in increasing submaximal muscle strength in elderly women inexperienced in RT after 12 weeks of intervention (p ≤ 0,05). However, DUP appears to be more effective in increasing functional capacity. In practice, the professional can use both the LP and the DUP to improve the level of fitness in the early stages of training in this population. However, when the goal of programming is to increase functional capacity, DUP can be prioritized.

Resumo O objetivo do presente estudo foi analisar o efeito de dois tipos diferentes de programação do treinamento de força (linear e ondulatório diário) na força submáxima e na capacidade funcional de mulheres idosas. Vinte e duas participantes (64 ± 3 anos) foram randomizados em 2 grupos experimentais: programação linear (PL; n=12) e programação ondulatória diária (POD; n=10). A capacidade funcional e a força submáxima (10RM) foram avaliadas antes e depois das 12 semanas de treinamento de força. Os resultados demonstraram melhora da força submáxima e da capacidade funcional após o período de treinamento (p ≤ 0,05), exceto para o exercício supino (p = 0,30), para ambos os grupos POD e PL. Foi encontrado um tamanho de efeito grande para a POD nos testes de sentar e caminhar = -2,07 e teste de sentar e levantar = 4,69, bem como na PL para o exercício leg press horizontal = 2,35. Não foi observada diferença estatística entre os modelos de programação. As programações LP e DUP têm resultados semelhantes no aumento da força muscular submáxima em mulheres idosas inexperientes em TR após 12 semanas de intervenção (p ≤ 0,05). No entanto, o DUP parece ser mais eficaz para aumentar a capacidade funcional. Na prática, o profissional pode usar tanto o LP quanto o DUP para melhorar o nível de condicionamento físico nos estágios iniciais do treinamento nessa população. Porém, quando o objetivo da programação é aumentar a capacidade funcional, o DUP pode ser priorizado.

https://doi.org/10.1590/1980-0037.2023v25e77528

Pediatric incontinence questionnaire (PINQ): translation and transcultural adaptation to Brazilian Portuguese
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Pereira, Rita Pavione Rodrigues

; Leitão, Angélica Quintino

; Fotakos, Gabriella Silva

; Reis, Joceara Neves dos

; Rocha, Flávio Eduardo Trigo

; Machado, Marcos Giannetti

; Bower, Wendy F.

; Tanaka, Clarice

Jornal de Pediatria

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2023, Volume 99 N. 4 Pages 379 - 384

Abstract: En | Text: En | PDF: En

Abstract Objective Lower urinary tract symptoms (LUTS) affect approximately 10% of children worldwide and are related to psychosocial manifestations and compromised quality of life, both for children and their families. The assessment of emotional conditions of LUTS in children is recommended by International Children's Continence Society; however, there is no specific instrument in the Brazilian Portuguese language. Therefore, the aim of this study was to translate, culturally adapt and assess the internal consistency of the Brazilian Portuguese version of the Pediatric Incontinence Questionnaire (PINQ). Material and methods This cross-sectional study was performed at two referral centers for childhood voiding dysfunction. The 20-item PINQ was translated into Brazilian Portuguese and culturally adapted according to Beaton, 2000. His-standard methodology consists of 6 phases: translation, synthesis, back-translation, expert committee, and pre-test. The internal consistency was assessed using Cronbach's alpha. Results The PINQ-br version was developed, validated by a committee of experts, and pre-tested on 44 children diagnosed with lower urinary tract symptoms, 23 boys and 21 girls (mean age: 9.7 and 9.6 years old respectively), as well as on their parents. The internal consistency was considered satisfactory, reaching Cronbach's alpha coefficient of 0.74 when applied to children and 0.82 when applied to parents. Conclusions The PINQ was translated and culturally adapted to Brazilian Portuguese to assess the impact of LUTS on the health-related quality of life in Brazilian children and adolescents.

https://doi.org/10.1016/j.jped.2023.01.002

Leadership through a gender lens: Disparities in Dental Research
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Gatti-Reis, Luisa

; Mattos, Flávio Freitas

; Pordeus, Isabela Almeida

; Martins-Júnior, Paulo Antônio

; Coutinho, Danielle Carvalho de Oliveira

; Perazzo, Matheus França

; Paiva, Saul Martins

Brazilian Dental Journal

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2023, Volume 34 N. 6 Pages 100 - 109

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study aimed to analyze the 100 most-cited papers in Dentistry, with a focus on female leadership in dental research. Papers were retrieved from the Web of Science Core Collection (WoS- CC) in the category ‘Dentistry, Oral Surgery & Medicine’. Gender was assessed through WoS-CC, Scopus, ResearchGate, social media, institutional websites, and software that assigns gender according to first names (https://genderapi.io). Characteristics of authors in leadership roles were retrieved, such as affiliation, publication history, citations, H factor, and i500. The 100 most-cited papers in Dentistry were authored by 394 researchers, 326 (82.7%) men, and 68 (17.3%) women - there were 4.8 male authors for each female. Among the lead authors, there were 11.3 males for each female. Among female senior authors, there were 7 males for each female. Among lead/senior authors of the 100 most-cited papers (first and last authors, respectively), 18 were women. There was an increase in the participation of women in the top cited papers regardless of authorship role across the six decades, with a peak of two female authors in the first decade of the 21st century. For female authors in leadership roles, their publication history shows the time between their first and last papers in WoS-CC ranged from 4 to 42 years for lead authors and 1 to 39 years for senior authors. Women were found to be largely underrepresented as leaders of the 100 most-cited papers, highlighting pervasive gender inequalities in dental research publications.

Resumo Objetivou-se analisar os 100 artigos mais citados em Odontologia, com foco na liderança feminina na pesquisa odontológica. Os artigos foram identificados utilizando-se a base de dados Web of Science Core Collection (WoS-CC) na categoria ‘Dentistry, Oral Surgery & Medicine’. O gênero dos autores foi avaliado por meio do WoS-CC, Scopus, ResearchGate, mídias sociais, sites institucionais e um software que atribui gênero de acordo com o primeiro nome (https://genderapi.io). As características dos autores em papéis de liderança foram identificadas, como afiliação, histórico de publicação, número de citações, fator H e i500. Os 100 trabalhos mais citados em Odontologia foram de autoria de 394 pesquisadores, sendo 326 (82,7%) homens e 68 (17,3%) mulheres - foram 4,8 autores homens para cada mulher. Entre os primeiros autores, havia 11,3 homens para cada mulher. Entre os últimos autores, havia 7 homens para cada mulher. Entre os primeiros/últimos autores dos 100 artigos mais citados, 18 eram mulheres. Houve um aumento na participação de mulheres nos artigos mais citados, independentemente do papel da autoria ao longo das seis décadas, com um pico de duas autoras na primeira década do século XXI. Para autoras em papéis de liderança, seu histórico de publicação mostra que o tempo entre o primeiro e o último artigo no WoS-CC variou de 4 a 42 anos para primeiro autor principais e de 1 a 39 anos para último autor. Verificou-se que as mulheres estão sub-representadas como líderes dos 100 artigos mais citados, destacando-se desigualdades de gênero generalizadas nas publicações em pesquisa odontológica.

https://doi.org/10.1590/0103-644020230555959

BRS A705: an early-cycle, lodging-resistant irrigated rice cultivar with high yield A705 A earlycycle, earlycycle early cycle, cycle early-cycle lodgingresistant lodging resistant A70 A7
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Magalhães Júnior, Ariano Martins de

; Colombari-Filho, José Manoel

; Fagundes, Paulo Ricardo Reis

; Rangel, Paulo Hideo Nakano

; Cardoso, Élbio Treicha

; Breseghello, Flávio

; Nunes, Cley Donizete

; Castro, Adriano Pereira de

; Andres, Andre

; Cordeiro, Antonio Carlos Centeno

; Brito, Giovani Greigh de

; Pereira, José Almeida

; Neves, Péricles de Carvalho Ferreira

; Petrini, José Alberto

; Martins, José Francisco da Silva

; Theisen, Giovani

; Fragoso, Daniel Brito

; Abreu, Guilherme Barbosa

Crop Breeding and Applied Biotechnology

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2023, Volume 23 N. 2 elocation e44872325

Abstract: En | Text: En | PDF: En

Abstract BRS A705 is an early-maturing cultivar developed by Embrapa, recommended for irrigated cultivation. The plants have high tillering and moderate resistance to the main diseases. This cultivar has short stature, which confers a greater tolerance to lodging. It presents high yield and long and fine grains of excellent quality. A A70 earlymaturing early maturing Embrapa cultivation diseases stature lodging quality A7

https://doi.org/10.1590/1984-70332023v23n2c17

Lesões traumáticas de aorta em zona rural: série de casos com manifestações tardias e revisão dos aspectos terapêuticos rural
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Reis, José Maciel Caldas dos

; Ribeiro, Flávio Roberto Cavalleiro de Macêdo

; Koury Junior, Adib

; Melo, Glauco dos Santos

; Oliveira, Murilo Vasconcelos de

; Gomes, Vitor Hugo Guerreiro Américo

; Santos, José Victor Figueiredo dos

; Sarquis Neto Segundo, Sotero Gonçalves

Jornal Vascular Brasileiro

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2023, Volume 22 elocation e20220014

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As lesões traumáticas da aorta (LTA) torácica estão associadas a altas taxas de morbimortalidade. São classificadas de acordo com a extensão do dano, e a angiotomografia computadorizada tem as maiores sensibilidade e especificidade para identificar o grau de lesão e potenciais lesões associadas. As estratégias terapêuticas para LTA são baseadas no tipo de lesão, na extensão e nas lesões associadas. Pode auxiliar na definição de conduta também o grau de estabilidade do paciente, podendo ser manejo cirúrgico convencional, endovascular (TEVAR) ou conservador em casos selecionados. Entre os pacientes com anatomia vascular adequada, a cirurgia endovascular está associada a melhor sobrevida e a menos riscos. O objetivo deste artigo foi descrever uma série de quatro casos acompanhados em serviço terciário, em um estado com poucos serviços de alta complexidade. A terapêutica endovascular foi empregada como método preferencial. Os pacientes apresentaram evolução favorável sem complicações até a alta e encontram-se em acompanhamento ambulatorial. (LTA morbimortalidade dano paciente convencional TEVAR (TEVAR selecionados adequada riscos terciário complexidade preferencial encontramse encontram se ambulatorial

Abstract Traumatic thoracic aortic injuries (TTAI) are associated with high rates of morbidity and mortality. They are classified according to the extent of damage and computed tomography angiography has the highest sensitivity and specificity for identifying the degree of injury and potential associated lesions. Treatment strategies for TTAI are based on the type and extent of injury and associated lesions. The patient’s degree of stability can also help to define the choice of treatment, which can be conventional or endovascular surgery (EVAR) or even conservative management in selected cases. Among patients with adequate vascular anatomy, endovascular surgery is associated with better survival and fewer risks. The objective of this article is to describe a series of four cases followed up at a tertiary service in a Brazilian state that has few centers that provide high complexity care. Endovascular therapy was employed as the preferred method. All four patients had favorable outcomes, with no complications up to discharge, and are currently in outpatient follow-up. (TTAI mortality lesions patient s treatment EVAR (EVAR anatomy risks care method outcomes discharge followup. followup follow up. follow-up

https://doi.org/10.1590/1677-5449.202200141

10.

The 500th Lung Transplantation at the Faculdade de Medicina da Universidade de São Paulo: Reflecting on Our Journey and Looking Ahead th Paulo
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Reis, Flavio Pola dos

; Pêgo-Fernandes, Paulo Manuel

Sao Paulo Medical Journal

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2023, Volume 141 N. 4 elocation e20231414

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1516-3180.2023.1414030423

11.

Use of Octopus™ Tissue Stabilizer for Minimal Manipulation Approach of Bronchial Anastomosis in Lung Transplant Octopus
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Razuk Filho, Mauro

; Santos, Samuel Lucas dos

; Reis, Flavio Pola dos

; Abdalla, Luis Gustavo

; Fernades, Lucas Matos

; Pêgo-Fernandes, Paulo Manuel

Brazilian Journal of Cardiovascular Surgery

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2023, Volume 38 N. 6 elocation e20220413

Abstract: En | Text: En | PDF: En

ABSTRACT Bronchial anastomotic complications are a cause of grave concern for surgeons that perform lung transplantations. There are several risk factors that may lead to this complication, being inadequate surgical technique one of them, specifically regarding adequate exposure and manipulation of the bronchial stump and anastomosis. Here we report the use of Octopus™ Tissue Stabilizer as a mean to allow for a better exposure of the stump and facilitate a “no-touch” approach towards anastomosis. Systematic application of devices that facilitate the employment of the correct surgical techniques can have an effect in reducing the incidence of bronchial anastomotic complications. transplantations complication them anastomosis Octopus notouch no touch “no-touch

https://doi.org/10.21470/1678-9741-2022-0413

12.

O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos
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Pereira, Rui Antunes

; Sousa, Marta

; Cidade, José Pedro

; Melo, Luís

; Lopes, Diogo

; Ventura, Sara

; Aragão, Irene

; Lima Neto, Raul Miguel de Freitas

; Molinos, Elena

; Marques, Ana

; Cardoso, Nelson

; Marino, Flávio

; Monteiro, Filipa Brás

; Oliveira, Ana Pinho

; Silva, Rogério C

; Real, André Miguel Neto

; Banheiro, Bruno Sarmento

; Reis, Renato

; Adão-Serrano, Maria

; Cracium, Ana

; Valadas, Ana

; Ribeiro, João Miguel

; Póvoa, Pedro

; Tapadinhas, Camila

; Mendes, Vítor

; Coelho, Luís

; Maia, Raquel

; Freitas, Paulo Telles

; Ferreira, Isabel Amorim

; Ramires, Tiago

; Val-Flores, Luís Silva

; Cascão, Mariana

; Alves, Rita

; Rodeia, Simão C

; Barrigoto, Cleide

; Cardiga, Rosa

; Silva, Maria João Ferreira da

; Vale, Bruno

; Fonseca, Tatiana

; Rios, Ana Lúcia

; Camões, João

; Pérez, Danay

; Cabral, Susana

; Ribeiro, Maria Inês

; Mendes, João João

; Gouveia, João

; Fernandes, Susana Mendes

Revista Brasileira de Terapia Intensiva

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dec 2022, Volume 34 N. 4 Pages 433 - 442

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To analyze and compare COVID-19 patient characteristics, clinical management and outcomes between the peak and plateau periods of the first pandemic wave in Portugal. Methods: This was a multicentric ambispective cohort study including consecutive severe COVID-19 patients between March and August 2020 from 16 Portuguese intensive care units. The peak and plateau periods, respectively, weeks 10 - 16 and 17 - 34, were defined. Results: Five hundred forty-one adult patients with a median age of 65 [57 - 74] years, mostly male (71.2%), were included. There were no significant differences in median age (p = 0.3), Simplified Acute Physiology Score II (40 versus 39; p = 0.8), partial arterial oxygen pressure/fraction of inspired oxygen ratio (139 versus 136; p = 0.6), antibiotic therapy (57% versus 64%; p = 0.2) at admission, or 28-day mortality (24.4% versus 22.8%; p = 0.7) between the peak and plateau periods. During the peak period, patients had fewer comorbidities (1 [0 - 3] versus 2 [0 - 5]; p = 0.002) and presented a higher use of vasopressors (47% versus 36%; p < 0.001) and invasive mechanical ventilation (58.1 versus 49.2%; p < 0.001) at admission, prone positioning (45% versus 36%; p = 0.04), and hydroxychloroquine (59% versus 10%; p < 0.001) and lopinavir/ritonavir (41% versus 10%; p < 0.001) prescriptions. However, a greater use of high-flow nasal cannulas (5% versus 16%, p < 0.001) on admission, remdesivir (0.3% versus 15%; p < 0.001) and corticosteroid (29% versus 52%, p < 0.001) therapy, and a shorter ICU length of stay (12 days versus 8, p < 0.001) were observed during the plateau. Conclusion: There were significant changes in patient comorbidities, intensive care unit therapies and length of stay between the peak and plateau periods of the first COVID-19 wave.

RESUMO Objetivo: Analisar e comparar as características de pacientes críticos com a COVID-19, a abordagem clínica e os resultados entre os períodos de pico e de platô na primeira onda pandêmica em Portugal. Métodos: Este foi um estudo de coorte multicêntrico ambispectivo, que incluiu pacientes consecutivos com a forma grave da COVID-19 entre março e agosto de 2020 de 16 unidades de terapia intensiva portuguesas. Definiram-se as semanas 10 - 16 e 17 - 34 como os períodos de pico e platô. Resultados: Incluíram-se 541 pacientes adultos com mediana de idade de 65 [57 - 74] anos, a maioria do sexo masculino (71,2%). Não houve diferenças significativas na mediana de idade (p = 0,3), no Simplified Acute Physiology Score II (40 versus 39; p = 0,8), na pressão parcial de oxigênio/fração inspirada de oxigênio (139 versus 136; p = 0,6), na terapia com antibióticos na admissão (57% versus 64%; p = 0,2) ou na mortalidade aos 28 dias (24,4% versus 22,8%; p = 0,7) entre o período de pico e platô. Durante o período de pico, os pacientes tiveram menos comorbidades (1 [0 - 3] versus 2 [0 - 5]; p = 0,002); fizeram mais uso de vasopressores (47% versus 36%; p < 0,001) e ventilação mecânica invasiva na admissão (58,1% versus 49,2%; p < 0,001), e tiveram mais prescrição de hidroxicloroquina (59% versus 10%; p < 0,001), lopinavir/ritonavir (41% versus 10%; p < 0,001) e posição prona (45% versus 36%; p = 0,04). Entretanto, durante o platô, observou-se maior uso de cânulas nasais de alto fluxo (5% versus 16%; p < 0,001) na admissão, remdesivir (0,3% versus 15%; p < 0,001) e corticosteroides (29% versus 52%; p < 0,001), além de menor tempo de internação na unidade de terapia intensiva (12 versus 8 dias; p < 0,001). Conclusão: Houve mudanças significativas nas comorbidades dos pacientes, nos tratamentos da unidade de terapia intensiva e no tempo de internação entre os períodos de pico e platô na primeira onda da COVID-19.

https://doi.org/10.5935/0103-507x.20210037-pt

13.

Biobank – the key to personalized medicine
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Reis, Flavio Pola dos

; Pêgo-Fernandes, Paulo Manuel

Sao Paulo Medical Journal

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oct 2022, Volume 140 N. 5 Pages 625 - 626

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1516-3180.2022.1405.12072022

14.

[SciELO Preprints] - Trends analysis of lung cancer incidence and mortality in Grande Cuiabá, Mato Grosso, Brazil, 2000 to 2016
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Cabral, Juliana Fernandes Caló, Romero dos Santos Evangelista, Flávio de Macêdo Reis, Juliana Benevenuto Oliveira, Julio Fernando Pinto Lima, Fernanda Cristina da Silva de Galvão, Noemi Dreyer Silva, Ageo Mário Cândido da

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Publication date: 2022-04-19

Abstract: En Pt

Objective: To analyses lung cancer incidence and mortality trends to gender and age group in Grande Cuiabá between 2000 to 2016. Methods: Study of times series applying incidence data from the Population-Based Cancer Registry of Cuiabá, and mortality data from Mortality Information System. Annual Percentage Change and the Average Annual Percentage Change were calculated in the incidence and mortality rate through the Joinpoint regression. Results: It was observed between men a decrease of -2,2% in the overall incidence of lung cancer during the term of 2000-2016 and by age range: 40 to 49 years (-4,2%), 60 to 69 years (-2,0%) and 70 to 79 years (-9,4%), in this last age group it was between 2000-2009. The general mortality was stable on historical series, nonetheless, a decline between men of 50 to 59 years (-3,5%) among 2006 to 2016 and of 70 to 79 years among 2002-20011 (-6,3%) were observed. The incidence trends among female individuals maintained stable whereas the overall mortality trends had an increase of 7,2% between 2000-2012 and decrease of -34,1% between 2012-2016. Amid women from 50 to 79 years, there was a raise, ranging from 3,5% to 3,9% between 2000-2016. Conclusions: There is an evident disparity between the trends analysis of incidence and mortality of lung cancer among men and women, that can be explained by changes in smoking over time, for example, the adherence or not of the smoking withdraw program beside

Objetivo: Analisar as tendências de incidência e mortalidade por câncer de pulmão, por sexo e faixa etária, na Grande Cuiabá, entre 2000 a 2016. Método: Estudo de séries temporais, utilizando informações de incidência do Registro de Câncer de Base Populacional Cuiabá e de mortalidade do Sistema de Informação de Mortalidade. Foram calculadas a Variação Percentual Anual e a Variação Percentual Média Anual das taxas de incidência e mortalidade, através da regressão por Joinpoint. Resultados: Observou-se entre homens um decréscimo de -2,2% na incidência geral de câncer de pulmão entre 2000-2016 e por faixa etária: 40 a 49 anos (-4,2%), 60 a 69 anos (-2,0%) e 70 a 79 anos (-9,4%), sendo que esta última faixa entre 2000-2009. Para mortalidade geral foi estável na série histórica, porém foi observado decréscimo entre os homens de 50 a 59 anos (-3,5%) entre 2006-2016 e de 70 a 79 anos entre 2002-2011 (-6,3%). Para as mulheres as tendências de incidência se mantiveram estáveis, enquanto nas tendências de mortalidade geral houve aumento de 7,2% entre 2000-2012 e decréscimo de -34,1% entre 2012-2016. Entre mulheres de 50 a 79 anos houve um aumento, variando de 3,5% a 3,9% entre 2000-2016. Conclusão: Existe uma evidente disparidade nas análises de tendências de incidência e mortalidade de câncer de pulmão entre homens e mulheres, que podem ser explicados por mudanças do tabagismo ao longo do tempo, por exemplo, adesão ou não ao programa de abandono do tabagismo, além de diferenças sociais, culturais, econômicas e até mesmo biológicas.

https://doi.org/10.1590/1980-549720220014.supl.1.1

15.

Neurogenic bladder – concepts and treatment recommendations
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Truzzi, José Carlos

; Almeida, Fernando Gonçalves de

; Sacomani, Carlos Alberto

; Reis, Joceara

; Rocha, Flávio Eduardo Trigo

International braz j urol

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apr 2022, Volume 48 N. 2 Pages 220 - 243

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Bladder and urinary sphincter malfunctioning that results from some change in the central and/or peripheral nervous system is defined as neurogenic bladder. The urinary tract symptoms that can be related to its filling, emptying, or both have a significant impact on the quality of life of individuals. The present review was based on the document prepared for the public health system in Brazil as a treatment guidelines proposal. Material and Methods: Survey questions were structured as per PICO (Population, Intervention, Control, and Outcome). Search strategies were defined and performed in the MEDLINE/Pubmed, Embase, Epistemonikos and Google Scholar databases. The selection of articles followed the evidence hierarchy concept; evidence body was identified, and the quantitative study data were extracted. The quality of evidence and grade of recommendation were qualitatively assessed according to GRADE (Grading of Recommendations, Assessment, Development and Evaluations). Results: A total of 2.707 articles were identified, with 49 of them being selected to compose the basis for this review. Neurogenic bladder treatments were classified according to their focus on filling or emptying symptoms and sub- classified in pharmacological and surgical treatments. Conclusion: Treatment guidelines are important tools for the public health system to promote the best practice when treating neurogenic bladder patients.

https://doi.org/10.1590/s1677-5538.ibju.2021.0098

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