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au:RIBEIRO, JOSE FELIPE

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Primary somesthetic cortex involvement in fibromyalgia: review of neuroimage studies
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Menezes, Maria Mônica da Silva

; Campos, Flavio José Neto

; Maia, Marília Silveira

; Silva, Felipe Ribeiro Fernandes da

; Queiroz, Jeffeson Hildo Medeiros de

BrJP

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2024, Volume 7 elocation e20240002

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND AND OBJECTIVES: The mechanisms underlying nociplastic pain, such as fibromyalgia (FM), are not fully understood, however, it is believed that altered sensory processing and pain modulation play prominent roles in the maintenance of nociplastic pain. The hypothesis is that changes in the primary somesthetic cortex (S1) contribute to the generalized pain character of FM. The objective of this study was to evaluate the involvement of the primary somesthetic cortex in humans with fibromyalgia, as well as to investigate possible associations between S1 changes and clinical signs and symptoms of FM. CONTENTS: For this integrative review, the following databases were used: Pubmed and Web of Science, including observational studies carried out in humans with FM. In total, 541 studies were identified and four were included. The majority of studies are case-control studies, published between 2016 and 2022. In total, data from 161 individuals were included in this review. It was identified that there are morphological changes, hyperactivation and increased functional connectivity between S1 and periaqueductal gray matter and between S1 and anterior cingulate cortex. CONCLUSION: Patients with FM present morphological changes and hyperactivation in S1, as well as increased functional connectivity between S1 and periaqueductal gray matter and S1 and limbic system. Furthermore, different bilateral somatotropic subregions (legs, chest, fingers, hands, face and back) showed reduced functional connectivity in patients with FM. These regions are often presented as “tender points” in FM.

RESUMO JUSTIFICATIVA E OBJETIVOS: Os mecanismos subjacentes à dor nociplástica, como a fibromialgia (FM), não são totalmente compreendidos, contudo acredita-se que o processamento sensorial e a modulação da dor alterados desempenham papéis proeminentes para a manutenção da dor nociplástica. Com a hipótese de que alterações no córtex somestésico primário (S1) contribuam para o caráter de dor generalizada da FM, o objetivo deste estudo foi avaliar o envolvimento do córtex somestésico primário em humanos com FM, bem como investigar possíveis associações entre alterações de S1 com sinais e sintomas clínicos da FM. CONTEÚDO: Para esta revisão integrativa, foram utilizadas as seguintes bases de dados: Pubmed e Web of Science, incluindo estudos observacionais realizados em humanos com FM. No total, 541 estudos foram identificados e quatro foram incluídos. A maioria dos estudos são do tipo caso-controle, publicados entre 2016 e 2022. Ao todo, dados de 161 indivíduos foram incluídos. Foi identificado que há alterações morfológicas, hiperativação e aumento da conectividade funcional entre S1 e substância cinzenta periaquedutal e entre S1 e córtex cingulado anterior. CONCLUSÃO: Pacientes com FM apresentam alterações morfológicas e hiperativação em S1, bem como aumento da conectividade funcional entre S1 e substância cinzenta periaquedutal e S1 e sistema límbico. Ademais, diferentes sub-regiões somatotrópicas bilaterais (pernas, tórax, dedos, mãos, face e costas) apresentaram redução da conectividade funcional em pacientes com FM. Essas regiões são frequentemente apresentadas como “tender points” na FM.

https://doi.org/10.5935/2595-0118.20240002-en

The II Brazilian Guidelines for the pharmacological treatment of patients hospitalized with COVID-19 Joint Guidelines of the Associação Brasileira de Medicina de Emergência, Associação de Medicina Intensiva Brasileira, Associação Médica Brasileira, Sociedade Brasileira de Angiologia e Cirurgia Vascular, Sociedade Brasileira de Infectologia, Sociedade Brasileira de Pneumologia e Tisiologia and Sociedade Brasileira de Reumatologia
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Falavigna, Maicon

; Araujo, Cintia Laura Pereira de

; Barbosa, Alexandre Naime

; Belli, Karlyse Claudino

; Colpani, Verônica

; Dal-Pizzol, Felipe

; Silva, Rosemeri Maurici da

; Azevedo, Luciano César Pontes de

; Dias, Maria Beatriz Souza

; Amaral, José Luiz Gomes do

; Dorneles, Gilson Pires

; Ferreira, Juliana Carvalho

; Freitas, Ana Paula da Rocha

; Gräf, Débora Dalmas

; Guimarães, Hélio Penna

; Lobo, Suzana Margareth Ajeje

; Machado, Flávia Ribeiro

; Nunes, Michelle Silva

; Oliveira, Maura Salaroli de

; Parahiba, Suena Medeiros

; Rosa, Regis Goulart

; Santos, Vania Cristina Canuto

; Sobreira, Marcone Lima

; Veiga, Viviane Cordeiro

; Xavier, Ricardo Machado

; Zavascki, Alexandre Prehn

; Stein, Cinara

; Carvalho, Carlos Roberto Ribeiro de

Critical Care Science

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sep 2023, Volume 35 N. 3 Pages 243 - 255

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To update the recommendations to support decisions regarding the pharmacological treatment of patients hospitalized with COVID-19 in Brazil. Methods: Experts, including representatives of the Ministry of Health and methodologists, created this guideline. The method used for the rapid development of guidelines was based on the adoption and/or adaptation of existing international guidelines (GRADE ADOLOPMENT) and supported by the e-COVID-19 RecMap platform. The quality of the evidence and the preparation of the recommendations followed the GRADE method. Results: Twenty-one recommendations were generated, including strong recommendations for the use of corticosteroids in patients using supplemental oxygen and conditional recommendations for the use of tocilizumab and baricitinib for patients on supplemental oxygen or on noninvasive ventilation and anticoagulants to prevent thromboembolism. Due to suspension of use authorization, it was not possible to make recommendations regarding the use of casirivimab + imdevimab. Strong recommendations against the use of azithromycin in patients without suspected bacterial infection, hydroxychloroquine, convalescent plasma, colchicine, and lopinavir + ritonavir and conditional recommendations against the use of ivermectin and remdesivir were made. Conclusion: New recommendations for the treatment of hospitalized patients with COVID-19 were generated, such as those for tocilizumab and baricitinib. Corticosteroids and prophylaxis for thromboembolism are still recommended, the latter with conditional recommendation. Several drugs were considered ineffective and should not be used to provide the best treatment according to the principles of evidence-based medicine and to promote resource economy.

RESUMO Objetivo: Atualizar as recomendações para embasar as decisões para o tratamento farmacológico de pacientes hospitalizados com COVID-19 no Brasil. Métodos: A elaboração desta diretriz foi feita por especialistas, incluindo representantes do Ministério da Saúde e metodologistas. O método utilizado para o desenvolvimento rápido de diretrizes baseou-se na adoção e/ou adaptação de diretrizes internacionais existentes (GRADE ADOLOPMENT) e contou com o apoio da plataforma e-COVID-19 RecMap. A qualidade das evidências e a elaboração das recomendações seguiram o método GRADE. Resultados: Chegaram-se a 21 recomendações, incluindo recomendações fortes quanto ao uso de corticosteroides em pacientes em uso de oxigênio suplementar e recomendações condicionais para o uso de tocilizumabe e baricitinibe, em pacientes com oxigênio suplementar ou ventilação não invasiva, e de anticoagulantes, para prevenção de tromboembolismo. Devido à suspensão da autorização de uso, não foi possível fazer recomendações para o tratamento com casirivimabe + imdevimabe. Foram feitas recomendações fortes contra o uso de azitromicina em pacientes sem suspeita de infecção bacteriana, hidroxicloroquina, plasma convalescente, colchicina e lopinavir + ritonavir, além de recomendações condicionais contra o uso de ivermectina e rendesivir. Conclusão: Foram criadas novas recomendações para o tratamento de pacientes hospitalizados com COVID-19, como as recomendações de tocilizumabe e baricitinibe. Ainda são recomendados corticosteroides e profilaxia contra tromboembolismo, esta em caráter condicional. Vários medicamentos foram considerados ineficazes e não devem ser usados, no intuito de proporcionar o melhor tratamento segundo os princípios da medicina baseada em evidências e promover a economia de recursos.

https://doi.org/10.5935/2965-2774.20230136-en

Decomposition and release of nutrients from species of tropical green manure
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Mangaravite, José Carlos Soares

; Passos, Renato Ribeiro

; Andrade, Felipe Vaz

; Silva, Victor Maurício da

; Marin, Ericka Broetto

; Mendonça, Eduardo de Sá

Revista Ceres

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jun 2023, Volume 70 N. 3 Pages 114 - 124

Abstract: En | Text: En | PDF: En

ABSTRACT Decomposition processes and mineralization are essential to determine the time to deploy and manage species in consortia or rotations. The aim of this article was study the dynamics of biomass decomposition and release of macronutrients of plant residues of Fabacea. The species used were: jack bean (Canavalia ensiformis), pigeon pea (Cajanus cajan), dwarf mucuna (Mucuna deeringiana) and sunn hemp (Crotalaria juncea). The experiment was conducted in the field in a randomized block design, 4 x 5 factorial, four species of green manure and five times (0, 30, 60, 90, and 120 days). In the results, sunn hemp and pigeon pea had lower decomposition and release of C, N, K, and Mg. All species, K and P showed similar half-lives (t1/2). For N, sunn hemp presented the lowest coefficient of mineralization (k), 0.0040 g g-1 dia-1, associated with highest t1/2 (173.3 days), already, jack bean showed the highest k (0.0122 g g-1 dia-1) associated with the lowest t1/2 (56.8 days). In edaphoclimatic conditions, use of the jack bean and the dwarf mucuna is recommended for supply of nutrients in shorter periods of time for subsequent crops. However, sunn hemp and pigeon pea are recommended for greater persistence of mulch on the soil.

https://doi.org/10.1590/0034-737x202370030012

Knowledge regarding extracorporeal membrane oxygenation management among Brazilian pediatric intensivists: a cross-sectional survey
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Colleti Júnior, José

; Prata-Barbosa, Arnaldo

; Araujo, Orlei Ribeiro

; Tonial, Cristian Tedesco

; Oliveira, Felipe Rezende Caino de

; Souza, Daniela Carla de

; Lima-Setta, Fernanda

; Oliveira, Thiago Silveira Jannuzzi de

; Mello, Mary Lucy Ferraz Maia Fiuza de

; Amoretti, Carolina

; João, Paulo Ramos David

; Neves, Cinara Carneiro

; Oliveira, Norma Suely

; Costa, Cira Ferreira Antunes

; Garros, Daniel

Critical Care Science

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jan 2023, Volume 35 N. 1 Pages 57 - 65

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To assess Brazilian pediatric intensivists’ general knowledge of extracorporeal membrane oxygenation, including evidence for its use, the national funding model, indications, and complications. Methods: This was a multicenter cross-sectional survey including 45 Brazilian pediatric intensive care units. A convenience sample of 654 intensivists was surveyed regarding their knowledge on managing patients on extracorporeal membrane oxygenation, its indications, complications, funding, and literature evidence. Results: The survey addressed questions regarding the knowledge and experience of pediatric intensivists with extracorporeal membrane oxygenation, including two clinical cases and 6 optional questions about the management of patients on extracorporeal membrane oxygenation. Of the 45 invited centers, 42 (91%) participated in the study, and 412 of 654 (63%) pediatric intensivists responded to the survey. Most pediatric intensive care units were from the Southeast region of Brazil (59.5%), and private/for-profit hospitals represented 28.6% of the participating centers. The average age of respondents was 41.4 (standard deviation 9.1) years, and the majority (77%) were women. Only 12.4% of respondents had taken an extracorporeal membrane oxygenation course. Only 19% of surveyed hospitals have an extracorporeal membrane oxygenation program, and only 27% of intensivists reported having already managed patients on extracorporeal membrane oxygenation. Specific extracorporeal membrane oxygenation management questions were responded to by only 64 physicians (15.5%), who had a fair/good correct response rate (median 63.4%; range 32.8% to 91.9%). Conclusion: Most Brazilian pediatric intensivists demonstrated limited knowledge regarding extracorporeal membrane oxygenation, including its indications and complications. Extracorporeal membrane oxygenation is not yet widely available in Brazil, with few intensivists prepared to manage patients on extracorporeal membrane oxygenation and even fewer intensivists recognizing when to refer patients to extracorporeal membrane oxygenation centers.

RESUMO Objetivo: Avaliar os conhecimentos gerais dos intensivistas pediátricos brasileiros sobre oxigenação por membrana extracorpórea, incluindo evidências de uso, modelo de custeio nacional, indicações e complicações. Métodos: Este estudo foi um inquérito transversal multicêntrico que incluiu 45 unidades de terapia intensiva pediátrica brasileiras. Realizou-se inquérito de conveniência com 654 intensivistas quanto aos seus conhecimentos sobre manejo de pacientes em oxigenação por membrana extracorpórea, suas indicações, complicações, custeio e evidências bibliográficas. Resultados: O inquérito abordou questões relativas aos conhecimentos e à experiência dos intensivistas pediátricos sobre oxigenação por membrana extracorpórea, incluindo dois casos clínicos e seis questões facultativas sobre o manejo de pacientes em oxigenação por membrana extracorpórea. Dos 45 centros convidados, 42 (91%) participaram do estudo, e 412 (63%) dos 654 intensivistas pediátricos responderam ao inquérito. A maioria das unidades de terapia intensiva pediátrica eram da Região Sudeste do Brasil (59,5%), e os hospitais privados com fins lucrativos representavam 28,6% dos centros participantes. A média de idade dos respondentes era de 41,4 (desvio-padrão de 9,1) anos, e a maioria (77%) era mulher. Apenas 12,4% dos respondentes tinham formação em oxigenação por membrana extracorpórea. Dos hospitais pesquisados, apenas 19% tinham um programa de oxigenação por membrana extracorpórea, e apenas 27% dos intensivistas declararam já ter manejado pacientes em oxigenação por membrana extracorpórea. Apenas 64 médicos (15,5%) responderam a questões específicas sobre o manejo de oxigenação por membrana extracorpórea (mediana 63,4%; oscilando entre 32,8% e 91,9%). Conclusão: A maioria dos intensivistas pediátricos brasileiros demonstrou conhecimentos limitados de oxigenação por membrana extracorpórea, incluindo suas indicações e complicações. A oxigenação por membrana extracorpórea ainda não está amplamente disponível no Brasil, com poucos intensivistas preparados para o manejo de pacientes em oxigenação por membrana extracorpórea e ainda menos intensivistas capazes de reconhecer quando devem encaminhar pacientes para centros de oxigenação por membrana extracorpórea.

https://doi.org/10.5935/2965-2774.20230350-en

Panorama das Intervenções Coronárias Percutâneas em Oclusões Totais Crônicas em Centros Participantes do LATAM CTO Registry no Brasil
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Silva, Antonio Carlos Botelho da

; Paula, João Eduardo Tinoco de

; Campos, Carlos M.

; Ribeiro, Marcelo Harada

; Martins Filho, Evandro

; Oliveira, Marcos Danillo Peixoto

; Côrtes, Leandro Assumpção

; Abelin, Aníbal Pereira

; Zukowski, Cleverson Neves

; Martinelli, Gustavo Cervino

; Brito, Fábio Sândoli de

; Muniz, Antônio José

; Cantarelli, Marcelo José de Carvalho

; Andrade, Pedro Beraldo de

; Medeiros, César Rocha

; Falcão, Breno de Alencar Araripe

; Fuchs, Felipe Costa

; Silva, Leonardo Sinnott

; Fattah, Tammuz

; Degrazia, Ramiro Caldas

; Mangione, José Armando

; Bezerra, Cristiano Guedes

; Baradel, Sandra

; Silveira, João Brum

; Ybarra, Luiz Fernando

; Weillenmann, Daniel

; Gottschall, Carlos

; Lemke, Viviana

; Silva, Franciele Rosa da

; Schmidt, Marcia Moura

; Belli, Karlyse Claudino

; Oliveira, Pedro Piccaro de

; Quadros, Alexandre Schaan de

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 4 elocation e20210462

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Major advances have been seen in techniques and devices for performing percutaneous coronary interventions (PCIs) for chronic total occlusions (CTOs), but there are limited real-world practice data from developing countries. Objectives To report clinical and angiographic characteristics, procedural aspects, and clinical outcomes of CTO PCI performed at dedicated centers in Brazil. Methods Included patients underwent CTO PCI at centers participating in the LATAM CTO Registry, a Latin American multicenter registry dedicated to prospective collection of these data. Inclusion criteria were procedures performed in Brazil, age 18 years or over, and presence of CTO with PCI attempt. CTO was defined as a 100% lesion in an epicardial coronary artery, known or estimated to have lasted at least 3 months. Results Data on 1196 CTO PCIs were included. Procedures were performed primarily for angina control (85%) and/or treatment of moderate/severe ischemia (24%). Technical success rate was 84%, being achieved with antegrade wire approaches in 81% of procedures, antegrade dissection and re-entry in 9%, and retrograde approaches in 10%. In-hospital adverse cardiovascular events occurred in 2.3% of cases, with a mortality rate of 0.75%. Conclusions CTOs can be treated effectively in Brazil by using PCI, with low complication rates. The scientific and technological development observed in this area in the past decade is reflected in the clinical practice of dedicated Brazilian centers.

Resumo Fundamento Tem sido observado um grande avanço nas técnicas e nos dispositivos para a realização de intervenções coronárias percutâneas (ICP) em oclusões totais coronarianas crônicas (OTC), mas existem poucos dados da prática do mundo real em países em desenvolvimento. Objetivos Relatar as características clínicas e angiográficas, os aspectos dos procedimentos e os resultados clínicos da ICP de OTC em centros dedicados a esse procedimento no Brasil. Métodos Os pacientes incluídos foram submetidos à ICP de OTC em centros participantes do LATAM CTO Registry, um registro multicêntrico latino-americano dedicado à coleta prospectiva desses dados. Os critérios de inclusão foram procedimentos realizados no Brasil, idade acima de 18 anos e presença de OTC com tentativa de ICP. A definição de OTC foi lesão de 100% em uma artéria coronária epicárdica, conhecida ou estimada como tendo pelo menos 3 meses de evolução. Resultados Foram incluídos dados de 1.196 ICPs de OTC. Os procedimentos foram realizados principalmente para controle da angina (85%) e/ou tratamento de uma grande área isquêmica (24%). A taxa de sucesso técnico foi de 84% e foi alcançada com técnicas de fios anterógrados em 81%, dissecção/reentrada anterógrada em 9% e retrógrada em 10% dos procedimentos. Os eventos cardiovasculares adversos intra-hospitalares ocorreram em 2,3% dos casos, sendo a mortalidade de 0,75%. Conclusões As OTC podem ser tratadas no Brasil por intervenção coronária percutânea de forma efetiva e com baixas taxas de complicações. O desenvolvimento científico e tecnológico observado nessa área na última década reflete-se na prática clínica de centros brasileiros dedicados a essa técnica.

https://doi.org/10.36660/abc.20210462

Dirofilaria immitis is endemic in rural areas of the Brazilian Amazonas state capital, Manaus
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Barbosa, Ulysses Carvalho

; Nava, Alessandra Ferreira Dales

; Ferreira Neto, José Vicente

; Dias, Cindy Alves

; Silva, Viviane Costa da

; Mesquita, Hugo Guimarães de

; Sampaio, Raquel Telles de Moreira

; Barros, Wanilze Gonçalves

; Farias, Emanuelle de Sousa

; Silva, Tullio Romão Ribeiro da

; Crainey, James Lee

; Tadei, Wanderli Pedro

; Koolen, Hector Henrique Ferreira

; Pessoa, Felipe Arley Costa

Revista Brasileira de Parasitologia Veterinária

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2023, Volume 32 N. 2 elocation e000223

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The canine filarial parasite Dirofilaria immitis has not been reported in Brazil´s Amazonas state capital, Manaus, for over a century. Here, we report one imported and 27 autochthonous D. immitis infections from a microfilarial survey of 766 domestic dog blood samples collected between 2017 and 2021 in Manaus. An Overall prevalence estimate of 15.44% (23/149) was calculated from our two rural collection sites; a prevalence of 1.22% (4/328) was estimated at our periurban collection site, and an overall prevalence of 0.35% (1/289) was calculated from our two urban clinic collections. Our data suggest that in the urban areas of Manaus, where the parasites are very likely vectored by the same species of mosquito that historically vectored Wuchereria bancrofti (Culex quinquefasciatus), prevalence levels are very low and possibly maintained by an influx from rural areas where sylvatic reservoirs and/or more favorable vector transmission dynamics maintain high prevalences.

Resumo O parasita filarial canino, Dirofilaria immitis, causa doença zoonótica, mas não tem sido registrado em Manaus, capital do estado do Amazonas, há mais de um século. Neste trabalho, foi relatado uma infecção por D. immitis alóctone e 27 autóctones de um levantamento de microfilárias em 766 amostras de sangue em cães domésticos, coletados entre 2017 e 2021 em Manaus. A prevalência de 15,44% (23/149) foi estabelecida em áreas rurais, 1,22% (4/328) para áreas periurbanas e de 0,35% (1/289) para duas clínicas veterinárias localizadas na zona urbana da cidade. Estes dados sugerem, portanto, que nas áreas urbanas de Manaus, nas quais o parasita é provavelmente vetorizado pela mesma espécie de mosquito que, historicamente, transmitiu Wuchereria bancrofti (Culex quinquefasciatus). Também os níveis de prevalência são baixos e, possivelmente, mantidos por um influxo de áreas rurais onde reservatórios silvestres e/ou dinâmicas de transmissão vetorial mais favoráveis mantêm uma prevalência mais elevada.

https://doi.org/10.1590/s1984-29612023018

Herd-level based seroprevalence and associated factors for Toxoplasma gondii in cows in the state of Paraíba, Northeastern Brazil
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Maia, Amanda Rafaela Alves

; Bezerra, Roberto Alves

; Silva, Samara Santos

; Álvares, Felipe Boniedj Ventura

; Santos, Carolina de Sousa Américo Batista

; Alves, Clebert José

; Clementino, Inácio José

; Feitosa, Thais Ferreira

; Vilela, Vinícius Longo Ribeiro

; Azevedo, Sérgio Santos de

Revista Brasileira de Parasitologia Veterinária

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2023, Volume 32 N. 2 elocation e017222

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract We aimed to determine the herd and animal levels seroprevalence and associated factors for Toxoplasma gondii infections in cattle from the state of Paraíba, Northeastern Brazil. Herds (n = 434) and cows aged ≥ 24 months (n = 1,895) were randomly selected, and serum samples were tested with the immunofluorescence antibody test (IFAT) using as cutoff of 64. Of the 434 farms investigated, 197 had at least one seropositive cow (prevalence of 49.0%; 95% CI = 44.3%-53.8%), and the prevalence at animal level was 18.0% (95% CI = 5.3%-21.1%). The antibody titers ranged from 64 to 1024, with the most frequent titers being 64 (10.8%) and 128 (3.7%). The risk factors identified were property located in Sertão region (odds ratio [OR] = 3.07), property located in Agreste/Zona da Mata regions (OR = 2.00), animal purchasing (OR = 2.68), herd size of 34-111 animals (OR = 2.91) and herd size > 111 animals (OR = 6.97). The results suggest the wide distribution of T. gondii infections in cattle throughout the state of Paraíba, and the risk factors identified are not possible to correct.

Resumo Objetivou-se determinar a soroprevalência do rebanhos e de animais e os fatores associados à infecção por Toxoplasma gondii em bovinos do estado da Paraíba, Nordeste do Brasil. Rebanhos (n = 434) e vacas com idade ≥ 24 meses (n = 1.895) foram selecionados aleatoriamente, e as amostras de soro foram testadas com o teste de imunofluorescência (RIFI), usando-se como ponto de corte 64. Das 434 fazendas investigadas, 197 tiveram pelo menos uma vaca soropositiva (prevalência de 49%; IC 95% = 44,3%-53,8%), e a prevalência em nível de animais foi de 18% (IC 95% = 5,3%-21,1%). Os títulos de anticorpos variaram de 64 a 1024, sendo os títulos mais frequentes 64 (10,8%) e 128 (3,7%). Os fatores de risco identificados foram na propriedade localizada na região do Sertão ("odds ratio" [OR] = 3,07), na propriedade localizada na região do Agreste/Zona da Mata (OR = 2,00), na compra de animais (OR = 2,68), no tamanho do rebanho de 34-111 animais (OR = 2,91) e no tamanho do rebanho > 111 animais (OR = 6,97). Os resultados sugerem a ampla distribuição de infecções por T. gondii em bovinos em todo o estado da Paraíba, e os fatores de risco identificados não são passíveis de correção.

https://doi.org/10.1590/s1984-29612023025

Endoparasites of marsupials in fragments of the Atlantic rainforest, western Paraná State, Brazil
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Benatti, Danise

; Moraes, Marcela Figueirêdo Duarte

; Pacheco, Carmen Andrea Arias

; Machado, Dália Monique Ribeiro

; Oliveira, Wilson Junior

; Perin, Patricia Parreira

; Andrietti, Luís Felipe

; Cândido Júnior, José Flávio

; Vogliotti, Alexandre

; Tebaldi, José Hairton

; Hoppe, Estevam Guilherme Lux

Revista Brasileira de Parasitologia Veterinária

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2023, Volume 32 N. 3 elocation e005823

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Knowledge of taxonomy and biodiversity of parasites is fundamental to better understand ecosystem dynamics. The objective of this study was to describe the helminth fauna of two species of marsupials in five fragments of the Atlantic rainforest in the western region of Paraná State, Brazil. In a total of 4050 trap-nights, the animals were captured using Sherman, Tomahawk, and Pitfall traps, euthanized, necropsied, and their organs inspected for helminths. After identification of the parasites, descriptors of infection, such as prevalence, mean abundance, mean intensity, and range of intensity, were calculated. Collectively, six helminth species were observed in 18 animals. The following five species were observed in Marmosa paraguayana: Viannaia hamata (58.8%), Gracilioxyuris agilisis (52.9%), Travassostrongylus sextus (17.6%), Oncicola luehei (5.9%), and Pritchardia boliviensis (5.9%). Whereas the following two species were observed in Monodelphis dimidiata: Trichohelix tuberculata (100%) and Travassostrongylus sextus (100%). This study represents a new locality record for all helminths described herein, and a new host for four helminth species. This is the first report on the helminth fauna of Monodelphis dimidiata, expanding knowledge about marsupials in the Brazilian Atlantic Forest.

Resumo Conhecimentos taxonômicos e da biodiversidade parasitária são fundamentais para uma melhor compreensão da dinâmica do ecossistema. O objetivo do estudo foi descrever a helmintofauna de marsupiais em cinco fragmentos de Mata Atlântica, na região Oeste do Estado do Paraná, Brasil. Em um total de 4.050 armadilhas/noite, os animais foram capturados com as do tipo Sherman, Tomahawk e Pitfall, eutanasiados, necropsiados e seus órgãos inspecionados em busca de helmintos. Após a identificação do parasita, foram calculados os indicadores de infecção (prevalência, abundância média, intensidade média e variação de intensidade). Seis espécies de helmintos foram observadas em dezoito animais; cinco em Marmosa paraguayana: Viannaia hamata (58,8%), Gracilioxyuris agilisis (52,9%), Travassostrongylus sextus (17,6%), Oncicola luehei (5,9%) e Pritchardia boliviensis (5,9%), e duas em Monodelphis dimidiata: Trichohelix tuberculata (100%) e Travassostrongylus sextus (100%). Este estudo representa um novo registro de localidade para todos os helmintos descritos e um novo hospedeiro para quatro deles. Trata-se do primeiro relato da helmintofauna de Monodelphis dimidiata, expandindo-se os conhecimentos sobre marsupiais na mata Atlântica brasileira.

https://doi.org/10.1590/s1984-29612023056

Natural infection of Lutzomyia longipalpis (Lutz & Neiva, 1912) by Leishmania infantum in a municipality with a high incidence of visceral leishmaniasis in the Brazilian Midwest
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Neitzke-Abreu, Herintha Coeto

; Andrade, Georgia Medeiros de Castro

; Almeida, Paulo Silva de

; Ribeiro, Gilmar Cipriano

; Ribeiro, Thaís Alves

; Barrios, D'Angela Maciel

; Pussi, Kamily Fagundes

; Andrade Filho, José Dilermando

; Dutra-Rêgo, Felipe

; Ovallos, Fredy Galvis

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0259-2023

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Here, Leishmania presence in sand flies from Três Lagoas, Mato Grosso do Sul, Brazil, after visceral leishmaniasis (VL) was investigated. Methods: In April 2022, two light traps were deployed within and around the residence for two days post-VL case report. Results: A total of 120 Lutzomyia longipalpis were collected. Suprapyloric flagellates were found in a female sand fly with eggs and residual blood during midgut dissection. Sequencing of ITS1 and cytb fragments confirmed Leishmania infantum DNA and identified Homo sapiens as the blood source, respectively. Conclusions: This study emphasizes the importance of monitoring sand flies in VL endemic areas.

https://doi.org/10.1590/0037-8682-0259-2023

10.

Assessment of the need for routine intraoperative cell salvage in liver transplantation
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Lima, Claudianne Maia de Farias

; Rebouças, Tatyane Oliveira

; Carlos, Luciana Maria de Barros

; Oliveira, Juliana Bezerra Frota

; Silva, Eulene Lima da

; Alves, Janaína Soares

; Lima, Clébia Azevedo de

; Mesquita, Felipe Pantoja

; Ribeiro, Jannison Karly Cavalcante

; Aquino, Pedro Everson Alexandre de

; Brunetta, Denise Menezes

; Garcia, José Huygens Parente

; Viana Júnior, Antonio Brazil

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e386423

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: This study aimed to assess the necessity of routine intraoperative cell salvage in liver transplantations. Methods: A total of 327 liver transplants performed between 2014 and 2016 was included in the analysis. Patient data, including pre-transplant examinations, intraoperative red blood cell transfusions, and procedural information, were collected. Results: The median age of the patients was 54 years old, with 67% (219) being male. The most prevalent ABO blood type was O, accounting for 48% (155) of cases. The leading causes of liver disease were hepatitis C (113 cases, 34.6%) and alcohol-related liver disease (97 cases, 29.7%). Out of the 327 liver transplants, allogeneic red blood cell transfusions were administered in 110 cases (34%) with a median of two units of red blood cells per case. Cell salvage was employed in 237 transplants (73%), and successful blood recovery was achieved in 221 cases (93%). Among the group that recovered more than 200 mL of blood, the median volume of recovered blood was 417 mL, with no transfusion of allogeneic blood required. A total of 90 transplants was performed without utilizing cell salvage, and, among these cases, 19 required blood transfusions, with a median of zero units transfused. Conclusions: This study suggests that routine cell salvage is unnecessary for all liver transplantations. The most suitable indication for its use is in patients presenting with portal vein thrombosis and abnormal creatinine levels.

https://doi.org/10.1590/acb386423

11.

Requirement for digestible lysine in Nile tilapias (Oreochromis niloticus) with live weight between 500 and 600 g
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Muniz Junior, José Claudio Bezerra

; Haidamus, Suzana Linhares

; Machado, Noédson de Jesus Beltrão

; Dilelis, Felipe

; Brasil, Ronner Joaquim Mendonça

; Quaresma, Débora Vaccari

; Lima, Cristina Amorim Ribeiro de

Acta Scientiarum. Animal Sciences

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2023, Volume 45 elocation e61547

Abstract: En | Text: En | PDF: En

ABSTRACT. The present study was carried out with the objective of determining the requirements for digestible lysine in Nile tilapia during the 500 to 600 g live weight stage. Isocaloric and isonitrogenous diets were tested with increasing amounts of digestible lysine. L-lysine HCl (78%) were used to replace glutamic acid at increasing levels, resulting in treatments of 9.3, 12.3, 15.3, 18.3 and 21.3 g kg-1 of digestible lysine. Three hundred Nile tilapias with an average weight of 519 ± 27.23 g were used and distributed among 25 tanks. The physical and chemical parameters of the water were pH, dissolved oxygen, salinity, conductivity and temperature. The mortality rate was registered daily. Two slaughters were performed at 28 and 50 days after the beginning of the experiment. It was estimated that an amount of 13.1 g kg-1 of digestible lysine was ideal for obtaining higher WG. Fish slaughtered after 50 days, the digestible lysine requirements were determined to be 14.5 g kg-1 for the lowest carcass humidity and 14.6 g kg-1 for the greatest carcass ethereal extract. Nile tilapias with live weight between 500 and 600 grams require 13.1 g kg-1 of digestible lysine in the diet for greater WG (90.53 g) and better FCR (2.55).

https://doi.org/10.4025/actascianimsci.v45i1.61547

12.

Chemical attributes of an Oxisol with the addition of conilon coffee straw biochar
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Alvarenga, Anarelly Costa

; Passos, Renato Ribeiro

; Andrade, Felipe Vaz

; Mendonça, Eduardo de Sá

; Rangel, Otacílio José Passos

; Mosa, Lázaro Longue

Pesquisa Agropecuária Brasileira

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2023, Volume 58 elocation e03019

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The objective of this work was to evaluate the effects of increasing rates of biochar produced with coffee straw, at two pyrolysis temperatures, on the chemical attributes of an Oxisol cultivated with conilon coffee (Coffea canephora) and on the nutrient content of coffee tree leaves. Treatments consisted of pyrolysis at two temperatures (350 and 600 °C) and of five biochar rates (0, 5, 10, 15, and 20 Mg ha-1). The following soil chemical attributes were evaluated: pH in water; P, K, Ca, Mg, Al, H+Al, Zn, Cu, Fe, and Mn contents; effective and potential cation exchange capacity (CEC); sum of bases (SB); base (V) and aluminium (m) saturation; and N, P, K, Ca, Mg, Zn, Cu, Fe, and Mn contents in the leaves. The biochar produced at 600°C, at rates of 10 and 15 Mg ha-1, promoted a greater K release into the soil. Regardless of temperature, coffee straw biochar increased K and P availability, sum of bases, base saturation, and CEC in the soil, but did not influence macro- and micronutrient contents in the leaves. The addition of increasing rates of coffee straw biochar in the soil increases P, K, Mg, SB, CEC, and V, regardless of pyrolysis temperature.

Resumo O objetivo deste trabalho foi avaliar os efeitos de doses crescentes de biocarvão produzido com palhada de café, em duas temperaturas de pirólise, nos atributos químicos de um Latossolo cultivado com cafeeiro conilon (Coffea canephora), e no conteúdo de nutrientes das folhas do cafeeiro. Os tratamentos consistiram de duas temperaturas de pirólise (350 e 600°C) e cinco doses de biocarvão (0, 5, 10, 15 e 20 Mg ha-1). Avaliaram-se os seguintes atributos químicos do solo: pH em água; teores de P, K, Ca, Mg, Al, H+Al, Zn, Cu, Fe e Mn; capacidade de troca catiônica efetiva e potencial (CTC); soma de bases (SB); saturação por bases (V) e por alumínio (m); e teores de N, P, K, Ca, Mg, Zn, Cu, Fe e Mn nas folhas. O biocarvão produzido a 600°C, nas doses de 10 e 15 Mg ha-1, promoveu maior liberação de K ao solo. Independentemente da temperatura, o biocarvão promoveu o aumento de P e K disponíveis, SB, V e CTC no solo, mas não influenciou os conteúdos dos macro e micronutrientes das folhas. A adição de doses crescentes de biocarvão da palha de café conilon no solo promove aumento de P, K, Mg, SB, CTC e V, independentemente da temperatura de pirólise.

https://doi.org/10.1590/s1678-3921.pab2023.v58.03019

13.

Spermine decreases ethylene and increases sugars and phenolic compounds in nasturtium flowers grown under drought and salt stress
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Silva, Toshik Iarley da

; Dias, Marlon Gomes

; Barbosa, Lucas Bretas

; Araújo, Nícolas Oliveira de

; Ferreira, Felipe Douglas

; Grossi, José Antônio Saraiva

; Costa, Franciscleudo Bezerra da

; Marco, Cláudia Araújo

; Ribeiro, Dimas Mendes

Bragantia

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2023, Volume 82 elocation e20230041

Abstract: En | Text: En | PDF: En

ABSTRACT Nasturtium (Tropaeolum majus) is an ornamental and medicinal plant that has edible flowers. Drought and salt stress decrease flower production and quality, including affecting sugar metabolism and ethylene production. Ethylene can accelerate the nasturtium senescence process, decreasing its postharvest quality. The use of polyamines, mainly spermine, may be a strategy for reducing the harmful effects of these stresses on the metabolism of sugars and phenolic compounds and for decreasing the production of ethylene, which accelerates senescence, in nasturtium flowers. Therefore, the objective here was to evaluate the role of spermine application on sugar and phenolic compounds and on ethylene production in nasturtium flowers grown under drought and salt stress. Two experiments were performed in isolation and at the same time in order to achieve this. Spermine down-regulated ethylene production and up-regulated the content of sugars and phenolic compounds on nasturtium flowers grown under drought and saline stress. Sugars and phenolic compounds down-regulated ethylene production in nasturtium flowers. Spermine can be used to mitigate the harmful effects of drought and salt stress on nasturtium flowers by increasing sugar and phenolic compounds and decreasing ethylene production. Tropaeolum majus quality process polyamines Therefore this downregulated down regulated upregulated up

https://doi.org/10.1590/1678-4499.20230041

14.

A framework to evaluate and compare synthetic streamflow scenario generation models
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Treistman, Felipe

; Penna, Débora Dias Jardim

; Khenayfis, Lucas de Souza

; Cavalcante, Nelson Bernardo Rodrigues

; Souza Filho, Francisco de Assis de

; Rocha, Renan Vieira

; Estácio, Ályson Brayner

; Rolim, Larissa Zaira Rafael

; Pontes Filho, João Dehon de Araújo

; Porto, Victor Costa

; Guimarães, Sullyandro Oliveira

; Pessanha, José Francisco Moreira

; Almeida, Victor Andrade de

; Chan, Priscilla Dafne Shu

; Lappicy, Thiago

; Lima, Carlos Henrique Ribeiro

; Detzel, Daniel Henrique Marco

; Bessa, Marcelo Rodrigues

RBRH

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2023, Volume 28 elocation e43

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A geração de cenários sintéticos de vazões afluentes é particularmente importante em países como o Brasil, onde a geração de energia hidrelétrica desempenha um papel fundamental e é crucial lidar adequadamente com a incerteza da vazão futura. Este artigo apresenta um esforço colaborativo do setor elétrico brasileiro para aprimorar os modelos de geração de cenários de vazão, com foco em horizontes de até um ano. Cinco instituições propuseram metodologias diversas e a sua eficácia foi avaliada através de uma avaliação comparativa estruturada. Os resultados revelam os pontos fortes e as áreas de possíveis aprimoramentos em cada modelo. O modelo GHCen apresentou o melhor desempenho, destacando-se nas análises de curto prazo e de média móvel, enquanto o modelo PARX demonstrou desempenho superior em regiões específicas do Brasil. O PAR(p)-A, metodologia oficial no Brasil, foi o segundo melhor modelo na análise de médias móveis. Este artigo oferece informações valiosas para países que enfrentam desafios semelhantes de programação hidrotérmica e geração de cenários. Brasil futura ano estruturada destacandose destacando se móvel PARpA, PARpA PAR p A, PAR(p)-A móveis

ABSTRACT Synthetic streamflow scenario generation is particularly important in countries like Brazil, where hydroelectric power generation plays a key role and properly handling the uncertainty of future streamflow is crucial. This paper showcases a collaborative effort within the Brazilian electrical sector to enhance streamflow scenario models, focusing on horizons up to one year. Five institutions proposed diverse methodologies, and their effectiveness was evaluated using a comparative framework. The results reveal the strengths and areas for improvement in each model. GHCen emerged as the top performer, excelling in both short-term and moving average analyses, while the PARX model demonstrated superior performance in specific regions. The PAR(p)-A, which is the official methodology in Brazil, was the second-best model in the moving average analysis. This research offers valuable insights for countries facing similar hydrothermal scheduling and scenario generation challenges. Brazil crucial models year methodologies framework performer shortterm short term analyses regions PARpA, PARpA PAR p A, A PAR(p)-A secondbest second best analysis challenges

https://doi.org/10.1590/2318-0331.282320230115

15.

Análise da aptidão física com a utilização de exergames em jovens futebolistas e não futebolistas: um estudo piloto
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Getirana-Mota, Márcio

; Paz, Ângelo de Almeida

; Vieira-Souza, Lúcio Marques

; Matos, Ricardo Santos

; Rosa, José Lucas Santos

; Costa, Lúcio Flávio Gomes Ribeiro da

; Teles, Luan José Lopes

; Aidar, Felipe José

Motricidade

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dec 2022, Volume 18 N. 2 Pages 230 - 236

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The objective of this research was to identify whether the use of exergames can help improve physical fitness through Burpee and analyse whether exergames can improve agility and spatial-temporal perception in young soccer players and non-players. This is a descriptive exploratory research with qualitative-quantitative data analysis. Participants were children (10.8 ± 1.8 years). For this sample, it was observed that exergames did not promote a significant increase in physical fitness (Group 1 × Group 2= 95%CI (-6.39–6.59), p> 1.00; Group 3 × Group 4= 95%CI (-1.27–3.47), p> 1.00). In contrast, exergames promoted a significant improvement in agility and spatiotemporal perception for group 2 (Agility Pre × Post: Z= -2.828; p= 0.05; Spatiotemporal perception Pre × Post: Z= -2.828; p= 0.05). We understand that exergames did not improve physical fitness in young soccer players and that they also did not provide improvements in agility or spatiotemporal perception. However, for the non-athlete public, there was a significant improvement in agility and spatial-temporal perception.

RESUMO O objetivo desta pesquisa foi identificar se a utilização do exergames pode auxiliar na melhora da aptidão física através do Burpee, como também, analisar se os exergames podem melhorar a agilidade e a percepção espaço-temporal em jovens jogadores de futebol e não jogadores. Esta pesquisa tem caráter exploratório descritivo com analise quali-quantitativa dos dados. Os participantes do estudo foram crianças (10,8± 1,8 anos). Para essa amostra, foi observado que o exergames não promoveu aumento significativo da aptidão física (Grupo 1 × Grupo 2= IC95% (-6,39–6,59), p> 1,00; Grupo 3 × Grupo 4= IC95% (-1,27–3,47), p> 1,00). Em contrapartida, o exergames promoveu melhora significativa da agilidade e da percepção espaço-temporal para o grupo 2 (Agilidade Pré × Pós: Z= -2,828; p= 0,05; Percepção espaço-temporal Pré × Pós: Z= -2,828; p= 0,05). Depreendemos que os exergames não proporciona melhora da aptidão física em jovens jogadores de futebol, e que também não proporcionou melhoras na agilidade ou na percepção espaço-temporal. Porém, para o público não atleta, houve melhora significativa para a agilidade e percepção espaço-temporal.

https://doi.org/10.6063/motricidade.27175

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