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ABSTRACT Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment of hypopituitarism, has increased the prevalence of this condition. Pituitary hormone deficiencies can induce significant clinical changes with consequent increased morbidity and mortality rates, while hormone replacement based on current guidelines protects these patients. In this review, we will first discuss the different etiologies of hypopituitarism and then address one by one the clinical aspects, diagnostic evaluation, and therapeutic options for deficiencies of TSH, ACTH, gonadotropin, and GH. Finally, we will detail the hormonal interactions that occur during replacement of pituitary hormones.

https://doi.org/10.20945/2359-3997000000335 625 downloads

Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital
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Marques, Heloisa Helena de Sousa

; Pereira, Maria Fernanda Badue

; Santos, Angélica Carreira dos

; Fink, Thais Toledo

; Paula, Camila Sanson Yoshino de

; Litvinov, Nadia

; Schvartsman, Claudio

; Delgado, Artur Figueiredo

; Gibelli, Maria Augusta Bento Cicaroni

; Carvalho, Werther Brunow de

; Odone Filho, Vicente

; Tannuri, Uenis

; Carneiro-Sampaio, Magda

; Grisi, Sandra

; Duarte, Alberto José da Silva

; Antonangelo, Leila

; Francisco, Rossana Pucineli Vieira

; Okay, Thelma Suely

; Batisttella, Linamara Rizzo

; Carvalho, Carlos Roberto Ribeiro de

; Brentani, Alexandra Valéria Maria

; Silva, Clovis Artur

; Eisencraft, Adriana Pasmanik

; Rossi Junior, Alfio

; Fante, Alice Lima

; Cora, Aline Pivetta

; Reis, Amelia Gorete A. de Costa

; Ferrer, Ana Paula Scoleze

; Andrade, Anarella Penha Meirelles de

; Watanabe, Andreia

; Gonçalves, Angelina Maria Freire

; Waetge, Aurora Rosaria Pagliara

; Silva, Camila Altenfelder

; Ceneviva, Carina

; Lazari, Carolina dos Santos

; Abellan, Deipara Monteiro

; Santos, Emilly Henrique dos

; Sabino, Ester Cerdeira

; Bianchini, Fabíola Roberta Marim

; Alcantara, Flávio Ferraz de Paes

; Ramos, Gabriel Frizzo

; Leal, Gabriela Nunes

; Rodriguez, Isadora Souza

; Pinho, João Renato Rebello

; Carneiro, Jorge David Avaizoglou

; Paz, Jose Albino

; Ferreira, Juliana Carvalho

; Ferranti, Juliana Ferreira

; Ferreira, Juliana de Oliveira Achili

; Framil, Juliana Valéria de Souza

; Silva, Katia Regina da

; Kanunfre, Kelly Aparecida

; Bastos, Karina Lucio de Medeiros

; Galleti, Karine Vusberg

; Cristofani, Lilian Maria

; Suzuki, Lisa

; Campos, Lucia Maria Arruda

; Perondi, Maria Beatriz de Moliterno

; Diniz, Maria de Fatima Rodrigues

; Fonseca, Maria Fernanda Mota

; Cordon, Mariana Nutti de Almeida

; Pissolato, Mariana

; Peres, Marina Silva

; Garanito, Marlene Pereira

; Imamura, Marta

; Dorna, Mayra de Barros

; Luglio, Michele

; Rocha, Mussya Cisotto

; Aikawa, Nadia Emi

; Degaspare, Natalia Viu

; Sakita, Neusa Keico

; Udsen, Nicole Lee

; Scudeller, Paula Gobi

; Gaiolla, Paula Vieira de Vincenzi

; Severini, Rafael da Silva Giannasi

; Rodrigues, Regina Maria

; Toma, Ricardo Katsuya

; Paula, Ricardo Iunis Citrangulo de

; Palmeira, Patricia

; Forsait, Silvana

; Farhat, Sylvia Costa Lima

; Sakano, Tânia Miyuki Shimoda

; Koch, Vera Hermina Kalika

; Cobello Junior, Vilson

Clinics

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2021, Volume 76 elocation e3488

Abstract: En | Text: En | PDF: En

OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results. RESULTS: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children (MIS-C) (OR 11.261; 95% CI 1.189-106. 581; p=0.035). CONCLUSIONS: Half of the laboratory-confirmed COVID-19 cases occurred in adolescents. Individuals belonging to this age group had an acute systemic involvement of SARS-CoV-2 infection. Pediatric SARS and MIS-C were the most important factors associated with the mortality rate in pediatric chronic conditions with COVID-19.

https://doi.org/10.6061/clinics/2021/e3488

[SciELO Preprints] - SARS-CoV-2 and Saliva: an update
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Muniz, Isis de Araújo Ferreira Linden, Lília Van der Santos, Mariana Evangelista Rodrigues, Raíres Chaves da Silva Souza, Joelma Rodrigues de Oliveira, Renato Antonio dos Santos Castellano, Lucio Roberto Cançado Bonan, Paulo Rogério Ferreti

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Publication date: 2020-06-05

Abstract: En

Covid-19 is a respiratory disease caused by the SARS-CoV-2 virus. The high rate of contagion and the spread of the virus in the population make the early detection of the pathogen the means for the adequate targeting of infection control measures. WHO directs sample collection on upper respiratory specimens, including nasopharyngeal and oropharyngeal swab or wash in ambulatory patients, as well as lower respiratory specimens: sputum and/or endotracheal aspirate or bronchoalveolar lavage, in addition to citing blood and feces. Among the various sample collection methods, saliva has been investigated and reported as a potential source for diagnosis. Thus, we propose to evaluate the current scenario, based on recent publications on the perspective of detecting SARS-CoV-2 in saliva as a diagnostic method for Covid-19.

https://doi.org/10.1590/SciELOPreprints.696

SARS-CoV-2 and Saliva as a Diagnostic Tool: A Real Possibility
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Muniz, Isis de Araújo Ferreira

; Linden, Lília Van der

; Santos, Mariana Evangelista

; Rodrigues, Raíres Chaves da Silva

; Souza, Joelma Rodrigues de

; Oliveira, Renato Antonio dos Santos

; Castellano, Lucio Roberto Cançado

; Bonan, Paulo Rogério Ferreti

Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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2020, Volume 20 Suppl. 1 elocation e0112

Abstract: En | Text: En | PDF: En

Abstract Covid-19 is a respiratory disease caused by the SARS-CoV-2 virus. The high rate of contagion and the spread of the virus in the population make the early detection of the pathogen the means for the adequate targeting of infection control measures. WHO directs sample collection on upper respiratory specimens, including nasopharyngeal and oropharyngeal swab or wash in ambulatory patients, as well as lower respiratory specimens: sputum and/or endotracheal aspirate or bronchoalveolar lavage, in addition to citing blood and feces. Among the various sample collection methods, saliva has been investigated and reported as a potential source for diagnosis. Thus, we propose to evaluate the current scenario, based on recent publications on the perspective of detecting SARS-CoV-2 in saliva as a diagnostic method for Covid-19. The detection of SARS-CoV-2 through saliva seems to be very promising, although obstacles such as the technique and the location of the collection and the sample size of the research carried out so far may present a limitation for its use. The current scenario presents saliva as a reliable method for the detection of SARS-CoV-2, due to the ease of obtaining the samples, the possibility of self-collection, low cost because there is no need to use specific equipment, in addition to reducing the risk of transmission for health professionals.

https://doi.org/10.1590/pboci.2020.126 1824 downloads

Anti-Biofilm and Hemolytic Effects of Cymbopogon citratus (Dc) Stapf Essential Oil
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Silva, Naiana Braga da

; Rangel, Marianne de Lucena

; Castro, Ricardo Dias de

; Lima, Jefferson Muniz de

; Castellano, Lúcio Roberto Cançado

; Valença, Ana Maria Gondim

; Cavalcanti, Alessandro Leite

Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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2019, Volume 19 elocation e5011

Abstract: En | Text: En | PDF: En

Abstract Objective: To perform chemical analysis and to evaluate the anti-biofilm and hemolytic effect of the essential oil of Cymbopogon citratus. Material and Methods: Gaseous chromatography coupled to mass spectrometer was performed for chemical characterization of the essential oil. To verify the antimicrobial action, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were determined. From MIC, MBC and MFC data, concentrations were established to verify the anti-biofilm effect and for the hemolysis test on human erythrocytes. A multispecies biofilm was developed in vitro and mouthwash applications were simulated to determine the inhibition of biofilm formation or its removal. Results were analyzed through ANOVA statistical test, complemented by the Tukey test, considering a significance level of 5% Results: The major component of the essential oil is citral. MIC verified for Streptococcus mutans was 1mg / mL, while for Candida albicans, it was 125 μg/mL, presenting microbicidal effect for both microorganisms tested. The essential oil was able to inhibit biofilm formation (p<0.001), presenting non-toxic hemolysis percentage in concentration below 500 μg/mL Conclusion: The essential oil of Cymbopogon citratus is antimicrobial, antibiofilm and non-toxic to human erythrocytes, representing a natural product with potential for use in Dentistry.

https://doi.org/10.4034/pboci.2019.191.103 444 downloads

Brazilian legislation on genetic heritage harms Biodiversity Convention goals and threatens basic biology research and education
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ALVES, RUY JOSÉ V.

; WEKSLER, MARCELO

; OLIVEIRA, JOÃO A.

; BUCKUP, PAULO A.

; POMBAL JR., JOSÉ P.

; SANTANA, HÉLCIO R.G.

; PERACCHI, ADRIANO LÚCIO

; KELLNER, ALEXANDER W.A.

; ALEIXO, ALEXANDRE

; LANGGUTH, ALFREDO

; ALMEIDA, ALZIRA MARIA P. DE

; ALBERNAZ, ANA LUISA

; RIBAS, CAMILA C.

; ZILBERBERG, CARLA

; GRELLE, CARLOS EDUARDO V.

; ROCHA, CARLOS F.D.

; LAMAS, CARLOS JOSÉ E.

; HADDAD, CÉLIO F.B.

; BONVICINO, CIBELE R.

; PRADO, CYNTHIA P.A.

; LIMA, DANIELA O. DE

; ROSSA-FERES, DENISE C.

; SANTOS, FABRÍCIO R. DOS

; SALIMENA, FÁTIMA REGINA G.

; PERINI, FERNANDO A.

; BOCKMANN, FLÁVIO A.

; FRANCO, FRANCISCO LUÍS

; GIUDICE, GISELE M.L. DEL

; COLLI, GUARINO R.

; VIEIRA, IMA CÉLIA G.

; MARINHO-FILHO, JADER

; WERNECK, JANE M.C.F.

; SANTOS, JORGE A.D. DOS

; NASCIMENTO, JORGE LUIZ DO

; NESSIMIAN, JORGE LUIZ

; CORDEIRO, JOSÉ LUIS P.

; CLARO, KLEBER DEL

; SALLES, LEANDRO O.

; CASATTI, LILIAN

; PY-DANIEL, LUCIA HELENA R.

; SILVEIRA, LUÍS FÁBIO

; TOLEDO, LUÍS FELIPE

; OLIVEIRA, LUIZ F. DE

; MALABARBA, LUIZ ROBERTO

; SILVA, MARCELO D. DA

; COURI, MÁRCIA S.

; MARTINS, MÁRCIO

; TAVARES, MARCOS D.S.

; SOBRAL, MARCOS EDUARDO G.

; VIEIRA, MARCUS VINÍCIUS

; OLIVEIRA, MARIA DE LOURDES A.

; PINNA, MÁRIO DE

; HOPKINS, MICHAEL J.G.

; SOLÉ, MIRCO

; MENEZES, NAÉRCIO A.

; PASSOS, PAULO

; D’ANDREA, PAULO SERGIO

; PINTO, PEDRO C.E.A.

; VIANA, PEDRO L.

; TOLEDO, PETER M.

; REIS, ROBERTO E.

; VILELA, ROBERTO

; BASTOS, ROGÉRIO P.

; COLLEVATTI, ROSANE G.

; CERQUEIRA, RUI

; CASTROVIEJO-FISHER, SANTIAGO

; CARAMASCHI, ULISSES

Anais da Academia Brasileira de Ciências

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apr 2018, Volume 90 N. 2 Pages 1279 - 1284

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0001-3765201820180460 7311 downloads

Solid phase extraction using molecular imprinting polymers (MISPE) for the determination of estrogens in surface water by HPLC
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Bianchi, Viviane do Nascimento

; Silva, Marcos Roberto de Araujo

; Lamim, Marcus Augusto

; Silva, Clovis Lucio da

; Lima, Elizabete Campos de

Revista Ambiente & Água

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may 2017, Volume 12 N. 3 Pages 380 - 389

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Estrogênios são poluentes emergentes e os tratamentos de esgoto tradicionais não são capazes de removê-los. São prejudiciais à saúde humana e ao ambiente. Portanto, torna-se importante avaliar a presença e concentração dessas substâncias em corpos hídricos e matrizes ambientais. No presente trabalho, apresenta-se o desenvolvimento e aplicação de uma metodologia para a determinação de E1, E3, EE2, E2 em águas superficiais utilizando a extração em fase sólida com polímeros de impressão molecular (MISPE) seguida da identificação e quantificação via HPLC-DAD. A fase móvel empregada foi acetonitrila e água acidificada, com ácido fosfórico, pH 3, (1:1, v/v), vazão 1,0 mL min-1, 40ºC, injeção 5 µL e λ = 280 nm. O método foi validado segundo o protocolo ICH Q2 R1. Testes de reprodutibilidade e repetibilidade resultaram em coeficientes de variância menores que 10%, e as curvas de calibração na faixa de concentração de 1 a 20 mg L-1 retornaram valores de linearidade maiores que 0,99. Os limites de detecção e quantificação ficaram abaixo de 1 mg L-1 e o método mostrou-se satisfatório para testes de especificidade e seletividade usando cafeína encontrada em corpos hídricos que recebem efluentes, e DES, estrogênio utilizado em tratamento de câncer de próstata. Amostras selecionadas foram submetidas a clean-up e pré-concentração utilizando extração em fase sólida com fase comercial (C18) e polímeros de impressão molecular (MISPE). Os extratos MISPE analisados indicaram que é possível obter resultados com maior sensibilidade e precisão para análises de matrizes ambientais complexas; mostrando que o método desenvolvido pode ser aplicado em matrizes ambientais complexas.

Abstract Estrogens are emerging pollutants and traditional sewage treatments unable to remove them. They are harmful to human health and to the environment. It is therefore important to evaluate the presence and concentration of estrogens in water bodies and environmental matrices. This work presents the development and application of a methodology for the determination of E1, E3, EE2 and E2 in surface waters using solid phase extraction with molecular imprinting polymers (MISPE) followed by identification and quantification by HPLC-DAD. Acetonitrile and water deionized acidified with phosphoric acid pH 3 (1:1, v/v), a flow rate of 1.0 ml min-1, at 40°C and an injection volume of 5 µL. The method was validated according to the protocol ICH Q2R. Reproducibility and repeatability tests resulted in a smaller variation coefficient of 10%; the calibration curves in the concentration ranged from 1 to 20 mg L-1, with return linearity values greater than 0.99. The limits of detection and quantification were less than 1 mg L-1 and the method was satisfactory for specificity and selectivity tests using caffeine, which is often found in water bodies receiving effluent, and DES, an estrogen used in the treatment of prostate cancer. Selected samples underwent clean-up and pre-concentration treatments using solid phase extraction with commercial phase (C18) and molecularly imprinted polymers (MISPE). The analysis of MISPE extracts indicate that it is possible to obtain results with greater sensitivity and precision for analyses of complex environmental matrices, demonstrating that the developed method can be applied in complex environmental matrices.

https://doi.org/10.4136/ambi-agua.1991 1646 downloads

Morphoanatomy and histochemistry analyses of cassava roots do not discriminate resistant from susceptible genotypes to soft root rot
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SILVA, Jonny Lucio Sousa

; MOURA, Elisa Ferreira

; ILKIU-BORGES, Fernanda

; GALVÃO, Jessivaldo Rodrigues

; FARIAS-NETO, João Tomé de

; SILVA, Gisele Barata da

; RÊGO, Marcela Cristiane Ferreira

; CUNHA, Roberto Lisboa

Acta Amazonica

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mar 2017, Volume 47 N. 1 Pages 1 - 6

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A mandioca é uma cultura importante no Brasil e no Norte do país, e a podridão mole da raiz tem afetado a produção. O objetivo deste trabalho foi identificar caracteres morfoanatômicos e histoquímicos da raiz associados à resistência à podridão da raiz. Em áreas sem ocorrência da doença, nove genótipos de mandioca foram testados, quatro resistentes e cinco suscetíveis. A colheita da raiz foi realizada doze meses após o plantio e medidas de espessura do súber, súber e cortex e xilema secundário foram realizadas. Além disso, foram analisados a textura, as camadas de célula do súber, o conteúdo de lignina e os monômeros de lignina da porção súber e cortex. Ainda, testes histoquímicos e microscopia eletrônica de varredura (MEV) das raízes foram realizados. Os resultados foram submetidos à análise de variância e as médias foram comparadas pelo teste de Scott-Knott (p≤0.05). Os caracteres: espessura de súber e córtex nas porções mediana e proximal, espessura do xilema secundário nas porções mediana e apical, número de camadas de células do súber, espessura do súber e textura da raiz apresentaram diferenças entre os genótipos, mas não associadas à resistência ou suscetibilidade. Não houve diferenças para: elementos de vaso, lignina e monômeros de lignina para os testes histoquímicos com Sudan IV e Lugol. Imagens de MEV apresentaram diferenças entre os genótipos, mas não associadas à resistência ou suscetibilidade. Assim, os caracteres avaliados não podem ser usados na seleção de mandioca com resistência à podridão mole da raiz em programa de melhoramento genético.

ABSTRACT Cassava is an important culture in Brazil and in the North of the country, and soft root rot has affected root production. The aim of this work was to identify root morphoanatomic and histochemical characters associated with root rot resistance. In areas with no occurrence of the disease, nine cassava genotypes were tested, four of which were resistant, and five were susceptible to root rot. Root harvest was carried out twelve months after sowing, and thickness of suber, suber and cortex, and secondary xylem were measured. Moreover, texture, suber cell layers, lignin content, and lignin monomers content of the portion suber and cortex were analyzed. Also, histochemical tests and scanning electron microscopy (SEM) analyses of the roots were performed. Results were subjected to analysis of variance, and means were compared by the Scott-Knott test (p ≤0.05). The characters thickness of suber and cortex at proximal and medium portions, thickness of secondary xylem at medium and apical portions, number of cell layers of suber, thickness of suber, and root texture showed differences among genotypes; however, the characters could not be associated with resistance or susceptibility. There were no differences for: vessel elements, lignin and lignin monomers, and for the histochemical tests with Sudan IV and Lugol. Images of SEM showed differences among genotypes, which could not be associated with resistance or susceptibility. Thus, the characters evaluated cannot be used in selection for cassava resistance to soft root rot in genetic breeding programs.

https://doi.org/10.1590/1809-4392201600513 3159 downloads

Sodium hypochlorite for removal of the sarcotesta from newly extracted and stored papaya seeds
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Jesus, Valquíria Aparecida Mendes de

; Araújo, Eduardo Fontes

; Santos, Fábio Lúcio

; Dias, Luiz Antônio dos Santos

; Silva, Roberto Ferreira da

Journal of Seed Science

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dec 2016, Volume 38 N. 4 Pages 358 - 364

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: Objetivou-se avaliar o efeito do hipoclorito de sódio na retirada da sarcotesta e no processo germinativo de sementes de mamão recém-extraídas, previamente armazenadas, antes e após armazenamento por 44 dias. Foram avaliados nove tratamentos segundo delineamento inteiramente casualizado, sendo seis tratamentos no esquema de parcelas subdivididas e três tratamentos adicionais (controles). As parcelas foram constituídas pelos métodos para quebra de dormência: M1 - Método da Peneira + Secagem a 7%; M2 - Método da Peneira + Secagem a 7% + NaOCl; e M3 - NaOCl + Secagem a 7%. As subparcelas pelo tempo de armazenamento (zero e 44 dias). Os três tratamentos adicionais consistiram em: A - NaOCl a 6% por 12 horas; B - Método da Peneira e C - Sementes intactas em 24 horas em água corrente. Avaliou-se o teste de germinação e a primeira contagem do teste de germinação. O uso do hipoclorito de sódio é eficiente para retirar a sarcotesta, porém afeta negativamente a germinação. O armazenamento por 44 dias é prejudicial à germinação. A remoção da sarcotesta pelo método da peneira, seguida da secagem até 7% de teor de água foi eficiente para propiciar a germinação das sementes de mamão.

Abstract: The objective of this study was to evaluate the effect of sodium hypochlorite on removal of the sarcotesta and the germination process of newly harvested papaya seeds before and after storage for 44 days. Nine treatments were evaluated using a completely randomized design with six treatments in a split plot arrangement and three additional treatments (control), each treatment with eight replications. The plots consisted of methods for breaking dormancy: M1 - sieve method + drying to 7%, M2 - sieve method + drying to 7% + NaOCl, and M3 - NaOCl + drying to 7%. The split plots consisted of different storage periods (0 and 44 days). The three additional treatments consisted of A - NaOCl at 6% for 12 hours, B - sieve method, and C - intact seeds in running water for 24 hours. Germination and the first count of germination were evaluated. Results showed that sodium hypochlorite is effective in removal of the sarcotesta, but there is a negative effect on germination. Storage for 44 days also had a negative effect on germination. Removal of the sarcotesta by the sieve method followed by drying to 7% moisture content was effective in promoting germination of papaya seeds.

https://doi.org/10.1590/2317-1545v38n4159502 1216 downloads

10.

Produtividade e qualidade da forragemde trigo-mourisco (Fagopyrum esculentum Moench) e de milheto (Pennisetum glaucum (L.) R.BR)
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GÖRGEN, Angela Valentini

; CABRAL FILHO, Sergio Lucio Salomon

; LEITE, Gilberto Gonçalves

; SPEHAR, Carlos Roberto

; DIOGO, José Mauro da Silva

; FERREIRA, Daniel Barcelos

Revista Brasileira de Saúde e Produção Animal

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dec 2016, Volume 17 N. 4 Pages 599 - 607

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivou-se com este trabalho comparar o valor forrageiro do milheto e trigo-mourisco, sob irrigação, em diferentes idades de corte. Utilizou-se delineamento experimental em blocos ao acaso, com os tratamentos arranjados em modelo de parcelas subdivididas. As plantas foram cultivadas durante a estação seca, sob irrigação e colhidas em três idades de corte, 47, 57 e 67 dias (tratamentos). Foram determinados os teores de matéria seca (MS), proteína bruta (PB), fibra em detergente neutro (FDN), fibra em detergente ácido (FDA), matéria mineral e produção de gases in vitro e a produção de matéria seca. A produção do trigo-mourisco (2301, 3144 e 4471 kg MS/ha) foi superior à do milheto (437, 592 e 2224 kg MS/ha) nas três idades de corte. Os teores de PB do milheto foram, em média, 22,3% nas três idades de corte, mas no trigo-mourisco reduziu de 23,8% no primeiro corte, para 14% nos demais cortes. O trigo mourisco apresentou maior teor de FDN no primeiro corte 57,6% contra 52,1% do milheto, entretanto diminuiu no segundo e terceiro cortes, 46,8% e 41,2%, respectivamente, enquanto que no milheto mantiveram-se em 55,1% e 52,7% no segundo e terceiro corte. Os teores de FDA forma mais elevados para o trigo mourisco em comparação com o milheto nas três idades de corte estudadas. A produção de gases foi maior para o trigo mourisco em comparação ao milheto, com exceção do primeiro corte, quando o trigo apresentou maiores taxas de fermentação. O trigo mourisco apresentou qualidade como forrageira, sendo mais produtivo e nutritivo do que o milheto durante o período seco, sob irrigação.

SUMMARY This trial compared forage production and quality of Pearl Millet and Buckwheat in three cutting age on irrigation conditions during dry season, evaluated in a randomized block split plot design with tree replications. Was determined content of Dry Matter (DM), Crude Protein (CP), Neutral Detergent Fiber (NDF), Acid Detergent Fiber (ADF), Mineral Matter (MM) and in vitro gas production. Forage production of Buckwheat was higher than Pearl Millet in all the cutting ages. Pearl Millet CP content was similar to all three cuts but Buckwheat CP content was higher in the first cut and reduced in the others. The NDF content of Buckwheat was higher in the first cut and reduced in the others, meanwhile Pearl Millet presented low NDF value in the first cut but increased in the second and third cut. The Buckwheat presented high ADF content than Pearl Millet in all the cuts. In vitro gas production from Pearl Millet was higher in the first cut but more high for Buckwheat in the second and third cuts. Buckwheat produced more forage with high quality than Pearl Millet during dry season.

https://doi.org/10.1590/s1519-99402016000400004 3468 downloads

11.

On the presence of the subnarial foramen in Prestosuchus chiniquensis (Pseudosuchia: Loricata) with remarks on its phylogenetic distribution
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ROBERTO-DA-SILVA, LÚCIO

; FRANÇA, MARCO A.G.

; CABREIRA, SÉRGIO F.

; MÜLLER, RODRIGO T.

; DIAS-DA-SILVA, SÉRGIO

Anais da Academia Brasileira de Ciências

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2016, Volume 88 N. 3 Pages 1309 - 1323

Abstract: En | Text: En | PDF: En

ABSTRACT Many authors have discussed the subnarial foramen in Archosauriformes. Here presence among Archosauriformes, shape, and position of this structure is reported and its phylogenetic importance is investigated. Based on distribution and the phylogenetic tree, it probably arose independently in Erythrosuchus, Herrerasaurus, and Paracrocodylomorpha. In Paracrocodylomorpha the subnarial foramen is oval-shaped, placed in the middle height of the main body of the maxilla, and does not reach the height of ascending process. In basal loricatans from South America (Prestosuchus chiniquensis and Saurosuchus galilei) the subnarial foramen is 'drop-like' shaped, the subnarial foramen is located above the middle height of the main body of the maxilla, reaching the height of ascending process, a condition also present in Herrerasaurus ischigualastensis. These results suggest that this structure might be phylogenetically important and further investigation with a large set of valid taxa is necessary to properly evaluate its importance among Archosauria.

https://doi.org/10.1590/0001-3765201620150456 2748 downloads

12.

Ratio of seeds and sodium hypochlorite solution on the germination process of papaya seeds
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Jesus, Valquíria Aparecida Mendes de

; Araújo, Eduardo Fontes

; Neves, Antônio Augusto

; Santos, Fábio Lúcio

; Dias, Luiz Antônio dos Santos

; Silva, Roberto Ferreira da

Journal of Seed Science

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mar 2016, Volume 38 N. 1 Pages 57 - 61

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: A sarcotesta, camada mucilaginosa presente nas sementes de mamão, afeta negativamente o seu processo germinativo e sua retirada tem sido realizada manualmente. O uso do hipoclorito de sódio pode ser uma alternativa à remoção manual da sarcotesta. Objetivou-se avaliar o efeito de diferentes concentrações de cloro ativo (0, 2, 4, 6 e 8%), durante 24 horas de imersão, em diferentes proporções (10:200, 50:200, 100:200, 200:200, 300:200, 400:200, 500:200 e 600:200) entre sementes (número) e volume (mL) da solução de hipoclorito de sódio respectivamente, visando identificar a melhor combinação para a retirada efetiva da sarcotesta de maneira a contribuir no processo germinativo. Foram avaliados o teste de germinação e a primeira contagem. Empregou-se o delineamento estatístico inteiramente casualizado com quatro repetições. Para as variáveis quantitativas, que apresentaram efeito significativo pelo teste F a 5% de probabilidade, foi realizada a análise de regressão. A imersão de sementes de mamão na proporção de 10 sementes por 200 mL de solução de NaOCl (10:200, ou seja, 20 mL de solução por semente), na concentração de 2% de cloro ativo por 24 horas, pode ser uma alternativa para a retirada da sarcotesta em sementes recém-colhidas, pois, além da retirada efetiva da sarcotesta, favorece a germinação.

Abstract: Sarcotesta, a mucilaginous layer found in papaya seeds, negatively affects the germination of papaya seeds and its removal has been manually performed. The use of sodium hypochlorite can be an alternative to manual removal of sarcotesta in papaya seeds. The objective of this study was to evaluate the effect of different active chlorine concentrations (0, 2, 4, 6 and 8%) during 24 hours of immersion, in different proportions (10:200, 50:200, 100:200, 200:200, 300:200, 400:200, 500:200 and 600:200) of seeds number and solution volume (mL) to identify the best combination for an effective remotion of sarcotesta to improve the germination process. Germination test and first count were performed. A completely randomized design with four replications was used. Regression analysis was performed for quantitative variables with significant effect by F-test at 5% probability. Papaya seeds immersion in the ratio of 10 seeds per 200 mL of NaOCl solution (10:200, i.e. 20 mL of solution per seed), at a 2% sodium hypochlorite concentration during 24 hours of imbibition, can be used as an alternative for sarcotesta remotion for freshly harvested papaya seeds, because besides the effective remotion of sarcotesta, this technique improves the germination process.

https://doi.org/10.1590/2317-1545v38n1151150 2273 downloads

13.

A Polissemia da Governança Clínica: uma revisão da literatura
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Gomes, Romeu

; Lima, Valéria Vernaschi

; Oliveira, José Maurício de

; Schiesari, Laura Maria Cesar

; Soeiro, Everton

; Damázio, Luciana Faluba

; Petta, Helena Lemos

; Oliveira, Marilda Siriani de

; Silva, Silvio Fernandes da

; Sampaio, Sueli Fatima

; Padilha, Roberto de Queiroz

; Machado, José Lúcio Martins

; Caleman, Gilson

Ciência & Saúde Coletiva

Journal Metrics
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aug 2015, Volume 20 N. 8 Pages 2431 - 2439

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

ResumoO artigo objetiva explorar a conceituação da gestão da clínica visando à compreensão dos diversos sentidos que poderão ser atribuídos a essa expressão. Essa discussão tanto pode contribuir para o planejamento e a organização dos serviços de saúde voltados para a gestão da clínica, quanto no estabelecimento de princípios para a elaboração de ações nessa área. Metodologicamente, o estudo consiste numa revisão bibliográfica de cunho qualitativo, com descritores da Biblioteca Virtual em Saúde (BVS). Em termos de resultados, destacam-se sete temas que sintetizam a análise das fontes: gestão, promoção da qualidade, monitoramento ou auditoria clínica, educação, responsabilidade, segurança no cuidado e dimensão sistêmica. Conclui-se que a variação de sentidos relaciona-se à forma como os autores dos estudos revisados expressam ou desdobram os componentes conceituais estruturantes amplamente aceitos como governança clínica. Observase que falta um maior foco em discussões sobre o planejamento e as políticas relacionadas à governança clínica.

AbstractThe article aims to explore the concept of clinical management, with a view towards understanding the diverse meanings that could be attributed to that expression. This discussion can contribute to the planning and organization of health services geared to the management of clinical practices, as well as to set forth principles to draft actions in that field. Methodologically, the study consists of a qualitative literature review, using keywords of the Virtual Health Library (VHL). In terms of results, seven topics stand out that synthesize the analysis of sources: management, quality promotion, clinical monitoring or auditing, education, responsibility or accountability, safety in care and a systemic dimension. The conclusion is that the variation of meanings relates to the way in which the authors of the studies reviewed express or unfold the structuring conceptual components broadly accepted as clinical governance. What we observe is a lack of a greater focus on discussions regarding planning and policies relating to clinical governance.

https://doi.org/10.1590/1413-81232015208.11492014 7184 downloads

14.

A Polissemia da Governança Clínica: uma revisão da literatura
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Gomes, Romeu

; Lima, Valéria Vernaschi

; Oliveira, José Maurício de

; Schiesari, Laura Maria Cesar

; Soeiro, Everton

; Damázio, Luciana Faluba

; Petta, Helena Lemos

; Oliveira, Marilda Siriani de

; Silva, Silvio Fernandes da

; Sampaio, Sueli Fatima

; Padilha, Roberto de Queiroz

; Machado, José Lúcio Martins

; Caleman, Gilson

Ciência & Saúde Coletiva

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2015, Volume 20 N. 8 Pages 2431 - 2439

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O artigo objetiva explorar a conceituação da gestão da clínica visando à compreensão dos diversos sentidos que poderão ser atribuídos a essa expressão. Essa discussão tanto pode contribuir para o planejamento e a organização dos serviços de saúde voltados para a gestão da clínica, quanto no estabelecimento de princípios para a elaboração de ações nessa área. Metodologicamente, o estudo consiste numa revisão bibliográfica de cunho qualitativo, com descritores da Biblioteca Virtual em Saúde (BVS). Em termos de resultados, destacam-se sete temas que sintetizam a análise das fontes: gestão, promoção da qualidade, monitoramento ou auditoria clínica, educação, responsabilidade, segurança no cuidado e dimensão sistêmica. Conclui-se que a variação de sentidos relaciona-se à forma como os autores dos estudos revisados expressam ou desdobram os componentes conceituais estruturantes amplamente aceitos como governança clínica. Observase que falta um maior foco em discussões sobre o planejamento e as políticas relacionadas à governança clínica.

Abstract The article aims to explore the concept of clinical management, with a view towards understanding the diverse meanings that could be attributed to that expression. This discussion can contribute to the planning and organization of health services geared to the management of clinical practices, as well as to set forth principles to draft actions in that field. Methodologically, the study consists of a qualitative literature review, using keywords of the Virtual Health Library (VHL). In terms of results, seven topics stand out that synthesize the analysis of sources: management, quality promotion, clinical monitoring or auditing, education, responsibility or accountability, safety in care and a systemic dimension. The conclusion is that the variation of meanings relates to the way in which the authors of the studies reviewed express or unfold the structuring conceptual components broadly accepted as clinical governance. What we observe is a lack of a greater focus on discussions regarding planning and policies relating to clinical governance.

https://doi.org/10.1590/1413-81232015208.11492014 1625 downloads

15.

Biomassa e Carbono em Euterpe oleracea Mart., na Ilha do Marajó - PA
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Miranda, Dirceu Lúcio Carneiro de

; Sanquetta, Carlos Roberto

; Costa, Luis Gonzaga da Silva

; Corte, Ana Paula Dalla

Floresta e Ambiente

Journal Metrics
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sep 2012, Volume 19 N. 3 Pages 336 - 343

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The purpose of this research was to quantify the individual stock of biomass and carbon fixed in Euterpe oleracea Mart., through the analysis of its carbon and dry biomass contents. Eighteen palm trees were analyzed divided in the following compartments: stem, edible part (palm), roots and foliage (bunches and fruits). The material was dried, weighed, crushed and grinded and it had its carbon contents determined. Carbon fraction means were as follows: 49.5% of carbon fixed for bunches and fruits, 45.5% fixed for roots, 42.8% for foliage, 41.2% for stem and 39.6% for the edible part, with weighted average of 43.1%. Statistical differences were observed despite the small variation in the carbon contents. The largest concentration of biomass (50%) and fixed carbon occurred in the stem. The equation Total Weight of Carbon TWC = 2.22017 + 2.29353 + 0.0148155 × Dap × Dap2hf satisfactorily represents the behavior of carbon stocks as a function of dbh; the different levels of carbon for each compartment should be taken into account for carbon quantification.

RESUMO Este trabalho teve por objetivo quantificar o estoque individual de biomassa e carbono fixado em Euterpe oleracea, por meio da análise de seus teores de carbono e da quantidade de biomassa seca. Foram analisadas 18 palmeiras, divididas nos compartimentos: fuste, parte comestível (palmito), raízes, folhagem e inflorescência (cachos e frutos). O material passou por secagem, pesagem, trituração e moagem, e pela determinação dos teores de carbono. A média dos teores de carbono fixo para os cachos e frutos foi 49,5%; raízes, 45,5%; folhagem, 42,8%; fuste, 41,2%, e parte comestível, 39,6%, com média ponderada de 43,1%. Apesar da pequena variação nos teores de carbono, houve diferenças estatísticas. A maior concentração de biomassa (50%) e carbono fixado encontra-se no fuste. A equação PCTotal = 2,22017 + 2,29353 × Dap + 0,0148155 × Dap2hf representa satisfatoriamente o comportamento do estoque de carbono em função do dap; para efeitos de quantificação de carbono, devem-se levar em consideração os diferentes teores de carbono para cada compartimento.

https://doi.org/10.4322/floram.2012.039

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