Abstract: Objective: To analyze the perception and intention to practice breastfeeding (BF) in adolescents of both genders who have not yet been parents. Material and Methods: This was a qualitative study based on grounded theory with empirical saturation. Twenty-one semi-structured interviews were conducted with students between 15 and 18 years of age in preparatory schools in Monterrey, Nuevo León, Mexico. Results: Four patterns on the perception and intention of practicing breastfeeding were identified: traditional; undecided; rejection; and egalitarian. Conclusions: The intention to support or practice BF is related to gender identities and the project of having children and / or a personal- labor development project. There is convergence between different perceptions and intentions to practice BF in the future, which aims to review policies in this area.

Resumen: Objetivo: Analizar la percepción e intención de práctica de la lactancia materna (LM) en adolescentes de ambos sexos que aún no han sido padres. Material y métodos: Se efectuó un estudio cualitativo basado en la teoría fundamentada y siguiendo el criterio de la saturación empírica. Se realizaron 21 entrevistas semiestructuradas a estudiantes entre 15 y 18 años de edad en preparatorias de la ciudad de Monterrey, Nuevo León, México. Resultados: Se identificaron cuatro patrones sobre la percepción e intención de practicar la LM: tradicional; indecisa; rechazo; e igualitarista. Conclusiones: La intención de apoyar o practicar la LM se relaciona a identidades de género y al proyecto de tener hijos y/o un proyecto de desarrollo personal-laboral. Existe convergencia entre distintas percepciones e intenciones de practicar la LM en el futuro, lo cual apunta a revisar las políticas en la materia.

RESUMEN Introducción: La lactancia materna (LM) es un factor protector contra la obesidad infantil; sin embargo, los mecanismos a través de los cuales ejerce este efecto aún no están claros. El objetivo fue describir los mecanismos asociados al efecto protector que ejerce la lactancia materna contra la obesidad infantil. Métodos: Se utilizaron los buscadores PUBMED, SCOPUS, Cochrane Library y Scielo para desarrollar una revisión descriptiva de la evidencia científica. Las palabras clave fueron: lactancia materna, obesidad, mecanismo y dieta. Se revisaron artículos en español e inglés, desde 1977 hasta el 2020. Resultados: El efecto protector de la LM contra la obesidad infantil está dado por una combinación de varios mecanismos, se destaca su composición nutricional y el aporte de sustancias bioactivas, algunas de ellas reguladoras de la ingesta energética. Los lactantes que reciben LM por más tiempo seleccionan alimentos más saludables en etapa preescolar, independiente de factores sociodemográficos. También han sido descritos efectos en la adiposidad, el control del peso corporal y la ingesta energética mediante regulación de la programación epigenética y de la microbiota intestinal. Conclusión: La LM es un proceso único, que interacciona de forma compleja con factores del crecimiento y desarrollo de los lactantes y preescolares. Su rol protector contra la obesidad ha sido asociado a diversos mecanismos. Sin embargo, se requiere de nuevas investigaciones para comprender los alcances que puede presentar la LM en la etapa pediátrica y su rol en la prevención de la obesidad.

ABSTRACT Background and aim: Breastfeeding (BF) is a protective factor against childhood obesity; however, the mechanisms associated with this effect have not yet been elucidated. This study aimed to describe the mechanisms related to the protective effect of breastfeeding against childhood obesity. Methods: A search on PUBMED, SCOPUS, Cochrane Library and SCIELO databases was carried out to develop a descriptive review of the scientific evidence. The key words were breastfeeding; obesity; mechanism and diet. Articles were reviewed in Spanish and English from 1977 to 2020. Results: The protective effect of BF against childhood obesity is given by a combination of several mechanism. Its nutritional composition and the contribution of bioactive substances stand out, some of them regulated by the energy intake. Infants who are breastfed choose healthier foods in preschool, regardless of sociodemographic factors. Effects on adiposity, control of body weight and energy intake have also been described by epigenetic regulation programming and the intestinal microbiota. Conclusion: BF is a unique process that interacts in a complex way with infants and preschoolers’ growth and developmental factors Its protective role against childhood obesity has been associated with various mechanisms. New research is still required to understand the implications of BF in pediatric age and its role in preventing obesity.

Abstract The genus Blepharocysta Ehrenberg currently comprises 5 species of truly marine planktonic thecate dinoflagellates, which are solitary, globose, subspherical and heterotrophic cells, lack typical depressed cingulum and sulcus, and are mainly distributed in tropical areas. The morphology of 2 species, Blepharocysta splendor-maris and B. paulsenii, found in net samples from the tropical Mexican Pacific, was studied by LM and SEM, especially plate arrangement and theca ornamentation. Blepharocysta splendor-maris showed more ovoid cells, developed sulcal lists, and theca with shallow poroids having a relative low density, whereas B. paulsenii had more spherical cells, shorter epitheca, reduced and slightly ornamented sulcal lists, and theca with deep poroids having a relatively higher density. The thecal tabulation in both species agrees with conventional tabulation, including the anterior intercalary plate in B. paulsenii. A comparison of both morphological and ecological characteristics among all species of the genus is done, outstanding shape of cells, relative size, development of sulcal lists, and especially the theca ornamentation as important morphological characters to distinguish species. Blepharocysta splendor-maris is the only species distributed from tropical to Antarctic waters, whereas the others are limited to tropical and subtropical waters.

Resumen El género Blepharocysta Ehrenberg comprende 5 especies de dinoflagelados tecados, planctónicos marinos. Incluye células solitarias, globulares, subesféricas y heterótrofas, que carecen de cingulum y sulcus típicos, de distribución principal en áreas tropicales. Se estudió la morfología de las especies Blepharocysta splendor-maris y B. paulsenii, encontradas en muestras de red del Pacífico mexicano tropical, usando ML y MEB, particularmente el arreglo de placas y ornamentación de la teca. Blepharocysta splendor-maris mostró una forma ovoide, aletas sulcales desarrolladas, teca con poroides poco profundos y mediana densidad, mientras que B. paulsenii tuvo forma más esférica, epiteca más corta, aletas sulcales reducidas, ligeramente ornamentadas y teca con poroides profundos, de mayor densidad. La tabulación de placas en ambas especies concuerda con la tabulación convencional, incluida la placa intercalar anterior en B. paulsenii. Se comparan las características morfológicas y ecológicas de las especies del género, destacando forma de células, tamaño relativo, desarrollo de las aletas sulcales y especialmente la ornamentación de la teca como caracteres morfológicos para distinguir especies. Blepharocysta splendor-maris es la única especie distribuida desde aguas tropicales a antárticas, mientras que las otras están limitadas a aguas tropicales y subtropicales.

Small and medium-sized enterprises (SMEs) are very important to national economies. In Brazil, the furniture sector has many SMEs that suffer from international competition, especially from Chinese companies. To reduce this difficulty, this study provides a case study of the partial implementation of lean manufacturing (LM) in a medium-sized furniture industry with the aim of increasing productivity. As a result, the company increased its productivity by 27 per cent in the drilling sector. In addition, the case study shows how to implement LM in a medium-sized furniture industry, demonstrating the need to adapt the system to companies outside the automobile sector.

Klein- en mediumgrootte ondernemings is baie belangrik vir nasionale ekonomieë. In Brasilië bevat die meubelbedryf vele kleinen mediumgrootte maatskappye wat swaar kry as gevolg van internasionale mededinging, veral van Sjinese ondernemings. Om hierdie uitdaging te oorkom bied dié artikel 'n gevallestudie van die gedeeltelike implementering van lenige vervaardiging in 'n mediumgrootte meubelmaatskappy met die doelstelling om produktiwiteit te verhoog. Die maatskappy se produktiwiteit is verhoog met 27 per sent in die boorsektor. Verder toon die gevallestudie hoe om lenige vervaardiging te implementeer in n mediumgrootte meubelmaatskappy. Sodoende word die behoefte om hierdie konsep aan te wend in ondernemings buite die tradisionele motorvervaardiging-sektor geïllustreer.

Over the last decade, Acinetobacter baumannii resistant to carbapenems has emerged in many medical centres and has been commonly associated with high morbimortality. In Brazil, this resistance is mainly attributed to the spread of OXA-23-producing clones and, to a lesser extent, to OXA-143-producing clones. Here, we describe, for the first time, two OXA-72-producing A. baumannii isolates in southern Brazil to a broad spectrum of antibiotics, except polymyxin B and tigecycline. Molecular typing by multilocus sequence typing (MLST) demonstrated that both OXA-72-producing isolates belong to a new sequence type (ST), ST730, which was recently identified in OXA-23-producing A. baumannii isolates in São Paulo, Brazil. We demonstrate that the two A. baumannii ST730 isolates carrying blaOXA-72share a common ancestral origin with the blaOXA-23producers in Brazil. This observation reinforces the importance of strain-typing methods in order to clarify the dynamics of the emergence of new clones in a geographic region.

RESUMO Avaliaram-se 160 radiografias das articulações coxofemorais de 40 cães de diferentes raças de grande porte, provenientes de Belo Horizonte, Brasil. As radiografias de cada animal foram obtidas em dois momentos: um (média de 7,23 meses de idade) e dois (média de 14,25 meses). Utilizaram-se o método radiográfico convencional (MRC) e o método radiográfico em distração (MRD), ambos realizados nos dois momentos. No MRC, mensurou-se o ângulo de Norberg (AN), o ângulo de inclinação (AI) e avaliou-se a presença de doença articular degenerativa (DAD). O MRD foi realizado para se estabelecer o índice de distração (ID). Os objetivos foram avaliar a presença da linha Morgan (LM) e de outros sinais de DAD, correlacionando-os com o grau de displasia coxofemoral (DCF); além de se verificar se o ID maior que 0,3 (primeiro momento) possui associação com a presença de LM (segundo momento). Verificou-se que ID, AI e encurtamento e/ou espessamento do colo femoral e formação de osteófitos foram associados à presença da LM. Observou-se que, quando o ID era maior que 0,3 no primeiro momento, a chance de um resultado positivo da LM no segundo momento aumentava em 7,2 vezes. No primeiro momento, 49 articulações apresentaram ID > 0,3. Destas, 31 (63,3%) apresentaram LM no segundo momento. Dos 31 animais que apresentaram ID ≤ 0,3 no primeiro momento, seis (19,4%) desenvolveram LM no segundo momento. Houve associação significativa entre presença de LM com o grau de DCF, e quanto mais grave a DCF, maior foi o percentual de resultados positivos da LM. Dos 24 (60%) animais que apresentaram LM, 11 (45,83%) foram classificados como displásicos graves, cinco (20,83%) como médios e oito (33,33%) como leves. Nenhum dos animais considerados suspeitos ou normais apresentou LM. Dos oito animais classificados como displásicos leves, cinco apresentaram apenas LM como sinal de DAD.

ABSTRACT We evaluated 160 hip joint radiographs of 40 dogs of different large breeds (25 females and 15 males) from the metropolitan area of Belo Horizonte, Minas Gerais, Brazil. The radiographs of each dog were obtained at two different stages: stage 1 (mean 7.23 months) and stage 2 (mean 14.25). The conventional radiographic method (CRM) and the radiographic distraction method (RDM) were used, carried out in both stages. CRM measured the Norberg angle (NA), the angle of inclination (AI) and evaluated the presence of degenerative joint disease (DJD). The MRD was performed to establish the distraction index (DI). The aims were to evaluate the presence of the Morgan line and other signs of DJD and correlate them with the degree of canine hip dysplasia (CHD) and also check if the DI greater than 0.3 (first stage) was associated with the presence of ML (second stage). It was found that DI, AI and changes of femoral neck and the formation of osteophytes were associated with the presence of ML. It was observed that if the DI is greater than 0.3 at the first stage, the chance of a positive outcome of ML in the second stage increases by 7.2 times. Thus, 49 joints showed DI > 0.3 at the first stage, in which 31 (63.3 %) presented ML at the second stage. Of the 31 animals that showed DI ≤ 0.3 at first, six (19.4%) had LM at the second stage. There has been a significant association between the presence of ML and the degree of CHD. The more severe the CHD, the higher the percentage of positive ML results. Thus, among the 24 (60 %) animals that showed ML, 11 (45.83 %) were classified as severe dysplastics, 5 (20.83%) as moderate and 8 (33.33 %) as mild. None of the animals classified as normal or borderline presented ML. Among the 8 animals classified as mild dysplastics, 5 showed only ML as DJD.

This retrospective study, performed in 2009, aimed to identify nursing diagnoses and interventions for the care of patients with spinal cord injury. Data were collected from the nursing records of 465 patients with SCI undergoing rehabilitation. The nursing diagnosis Risk for autonomic dysreflexia was identified in 271 clinical records (58, 3%). Approximately 80 patients developed autonomic dysreflexia, with a predominance in young men around 35.7 years old, who had experienced a trauma as the main cause of the injury. Their neurological injury level was at the sixth thoracic vertebra or above. Nursing interventions were arranged in two groups, one focused on prevention and the other on treatment. An intervention guide was developed and can be used by nurses in their clinical practice of rehabilitation and can be included into information systems. The removal of the stimulus which causes autonomic dysreflexia was identified as the most effective therapy and the best intervention

Estudio retrospectivas realizado en 2009 objetivando identificar diagnósticos e intervenciones de enfermería para el cuidado del paciente con lesión medular (LM). Datos colectados de 465 historias clínicas de pacientes con LM en rehabilitación. Se identificó el diagnóstico de enfermería Riesgo para disreflexia autonómica en 271 (58,3%) historias clínicas; 80 de tales pacientes desarrollaron Disreflexia autonómica. Predominaron hombres jóvenes, media etaria de 35,7 años, constituyéndose el trauma como causa principal de LM y nivel neurológico igual o por sobre sexta vértebra torácica. Las intervenciones de enfermería se organizaron en dos grupos: uno orientado a prevención de la disreflexia autonómica y otro para su tratamiento. Se desarrolló una guía de intervenciones para uso en práctica clínica de enfermeros rehabilitadores y para incorporación a sistemas de información. Se destaca la importancia de retirar el estímulo que provoca la disreflexia autonómica como terapéutica más eficaz y como mejor intervención en la práctica de enfermería.

O presente trabalho trata-se de estudo retrospectivo realizado em 2009 que objetivou identificar diagnósticos e intervenções de enfermagem para o cuidado de pacientes com lesão medular (LM). Os dados foram coletados de 465 prontuários de pacientes com LM em processo de reabilitação. Identificou-se o diagnóstico de enfermagem Risco para disreflexia autônomica em 271 (58,3%) prontuários, dos quais 80 pacientes desenvolveram disreflexia autônomica. Predominaram homens jovens, com idade média de 35,7 anos, sendo o trauma a principal causa da LM e o nível neurológico igual ou acima da sexta vértebra torácica. As intervenções de enfermagem foram organizadas em dois grupos, um voltado para a prevenção da disreflexia autonômica e outro, para seu tratamento. Desenvolveu-se um guia de intervenções para uso na prática clínica de enfermeiros reabilitadores e para inserção em sistemas de informação. Ressalta-se a importância da retirada do estímulo causador da disreflexia autonômica como terapêutica mais eficaz e como melhor intervenção na prática de enfermagem.

O presente trabalho trata-se de estudo retrospectivo realizado em 2009 que objetivou identificar diagnósticos e intervenções de enfermagem para o cuidado de pacientes com lesão medular (LM). Os dados foram coletados de 465 prontuários de pacientes com LM em processo de reabilitação. Identificou-se o diagnóstico de enfermagem Risco para disreflexia autônomica em 271 (58,3%) prontuários, dos quais 80 pacientes desenvolveram disreflexia autônomica. Predominaram homens jovens, com idade média de 35,7 anos, sendo o trauma a principal causa da LM e o nível neurológico igual ou acima da sexta vértebra torácica. As intervenções de enfermagem foram organizadas em dois grupos, um voltado para a prevenção da disreflexia autonômica e outro, para seu tratamento. Desenvolveu-se um guia de intervenções para uso na prática clínica de enfermeiros reabilitadores e para inserção em sistemas de informação. Ressalta-se a importância da retirada do estímulo causador da disreflexia autonômica como terapêutica mais eficaz e como melhor intervenção na prática de enfermagem.

This retrospective study, performed in 2009, aimed to identify nursing diagnoses and interventions for the care of patients with spinal cord injury. Data were collected from the nursing records of 465 patients with SCI undergoing rehabilitation. The nursing diagnosis Risk for autonomic dysreflexia was identified in 271 clinical records (58, 3%). Approximately 80 patients developed autonomic dysreflexia, with a predominance in young men around 35.7 years old, who had experienced a trauma as the main cause of the injury. Their neurological injury level was at the sixth thoracic vertebra or above. Nursing interventions were arranged in two groups, one focused on prevention and the other on treatment. An intervention guide was developed and can be used by nurses in their clinical practice of rehabilitation and can be included into information systems. The removal of the stimulus which causes autonomic dysreflexia was identified as the most effective therapy and the best intervention

Estudio retrospectivas realizado en 2009 objetivando identificar diagnósticos e intervenciones de enfermería para el cuidado del paciente con lesión medular (LM). Datos colectados de 465 historias clínicas de pacientes con LM en rehabilitación. Se identificó el diagnóstico de enfermería Riesgo para disreflexia autonómica en 271 (58,3%) historias clínicas; 80 de tales pacientes desarrollaron Disreflexia autonómica. Predominaron hombres jóvenes, media etaria de 35,7 años, constituyéndose el trauma como causa principal de LM y nivel neurológico igual o por sobre sexta vértebra torácica. Las intervenciones de enfermería se organizaron en dos grupos: uno orientado a prevención de la disreflexia autonómica y otro para su tratamiento. Se desarrolló una guía de intervenciones para uso en práctica clínica de enfermeros rehabilitadores y para incorporación a sistemas de información. Se destaca la importancia de retirar el estímulo que provoca la disreflexia autonómica como terapéutica más eficaz y como mejor intervención en la práctica de enfermería.

Real-time ultrasonography (RTU) was used to measure the longissimus dorsi muscle (LM) volume in vivo and to predict the carcass composition of rabbits. For this, 63 New Zealand White × Californian rabbits with 2093±63 g live weight were used. Animals were scanned between the 6th and 7th lumbar vertebrae using an RTU equipment with a 7.5 MHz probe. Measurements of LM volume were obtianed both in vivo and on carcass. Regression equations were used for the prediction of carcass composition and LM volume using the LM volume measured obtained with RTU (LMVU) as independent variable. Carcass meat, bone and total dissectible fat weights represented 780, 164 and 56 g/kg of the reference carcass weight, respectively. Regression equations showed a strong relationship between LMVU and the correspondent volume in carcass. Furthermore, LMVU was also useful in predicting the amounts of carcass tissues. It is possible to predict LM volume in the carcass using the LM volume measured in vivo by RTU. The amount of carcass tissues can be predicted by the LM volume measured in vivo by RTU.

INTRODUÇÃO: O treino locomotor com suporte parcial de peso (TLSP) pode ser aplicado na reabilitação de pessoas com lesão medular e proporcionar melhoras funcionais, da função cardiovascular e auxiliar na prevenção e tratamento da osteopenia e osteoporose, que são importantes complicações secundárias à LM. OBJETIVOS: Este estudo teve como objetivo determinar e comparar a densidade mineral óssea (DMO) antes e após seis meses de TLSP em sujeitos com LM incompleta. MÉTODO: A amostra foi composta por oito voluntários, com LM com classificações (ASIA) A, B e D. O grupo foi submetido a sessões de treinos, três vezes por semana, com duração de 15 minutos, a uma velocidade de 1,5 km/h. A descarga de peso sobre membros inferiores era aumentada em 5% do peso corporal a cada duas semanas, passando de 20% até 65% do peso corporal, desde o início até o fim do período. Foram realizados exames de densitometria óssea antes do início e logo após o encerramento do programa de treinamento. RESULTADOS: Houve aumento na DMO média do fêmur total que, apesar de pequeno (0,05 g/cm²), foi significativo (p = 0,034). Nas demais regiões (colo do fêmur e trocânter) não houve alteração significativa. CONCLUSÃO: O TLSP pode ter auxiliado na manutenção da DMO nas regiões do colo do fêmur e trocânter.

INTRODUCTION: Body weight support training (BWST) is a physical rehabilitation method applied for stimulating motor control recovery at neurological diseases. In the specific case of incomplete spinal cord injury (SCI), this method may help to improve functional capacity, cardiovascular function, as well as prevent and treat osteopenia and osteoporosis, which are important secondary complications of SCI. OBJECTIVE: This study has the purpose to determine and compare the bone mineral density (BMD) before and after six months of BWST in people with incomplete SCI. METHOD: The sample of this study was composed for eight ASIA A, B and D SCI volunteers who took part in 15 minutes training sessions, three times a week, carried out on treadmill with speed of 1,5 km/h. The load over lower limbs was increased every two weeks in 5% of body weight, from 20% until 65% of body weight, along six months. Bone densitometry tests were carried out before the beginning and just after the training program. RESULTS: There was a small (0,05 g/cm²), but significant (p = 0,034) improvement on femur BMD. In other regions (femoral neck and trochanter) there was no significant change (no gain or loss). CONCLUSION: The BWST can be aided by maintaining the BMD in the regions of femoral neck and trochanter.

INTRODUÇÃO: Recentemente a intervenção coronária percutânea (ICP) com stents farmacológicos (SFs) tem se mostrado uma opção viável em pacientes selecionados com lesão de tronco de coronária esquerda não-protegido (TCE-NP). Este estudo teve como objetivo avaliar a efetividade e a segurança da ICP com SFs em lesões de TCE-NP da prática diária, analisando a ocorrência combinada de eventos cardíacos adversos maiores (ECAM) a longo prazo. MÉTODOS: Foram tratados 142 pacientes consecutivos, com média de seguimento clínico de 917 ± 743 dias. A decisão de utilizar um ou dois stents e inibidor da glicoproteína IIb/IIIa ficou a critério do operador. Angiografia coronária no seguimento não foi realizada de rotina, mas deixada a critério clínico. RESULTADOS: A média de idade foi de 67,5 ± 16 anos, três quartos dos pacientes eram do sexo masculino, 29% eram portadores de diabetes e 39% apresentavam angina instável. Foram utilizados 2,75 ± 1,25 stents por paciente. Lesões com comprometimento da bifurcação foram identificadas em 90,1% e as técnicas mais frequentemente utilizadas foram o provisional stent em 36% e o small crush em 29% dos pacientes. Ultrassom intracoronário foi realizado em 92,3% dos pacientes, e reintervenção ocorreu em 21,3% dos stents, por apresentarem aposição incompleta de suas hastes após o implante. ECAM na evolução tardia ocorreram em 15,4%, óbito cardíaco ocorreu em 3,6%, revascularização do vaso-alvo em 11,2% e trombose definitiva/ provável do stent em 1,4%. CONCLUSÕES: A ICP com SFs em lesões de TCE-NP neste estudo mostrou ser segura e eficaz na evolução tardia, com baixas taxas de óbito cardíaco e de trombose do stent.

BACKGROUND: Recently, percutaneous coronary intervention (PCI) with drug-eluting stents (DES) has proven to be a feasible option in selected patients with unprotected left main (LM) disease. This study was aimed at assessing the efficacy and safety of PCI with DES in LM lesions in the daily practice, analyzing the long-term occurrence of major adverse cardiac events (MACE). METHODS: A total of 142 consecutive patients were treated with a mean follow-up of 917 ± 743 days. The decision to use one or two stents or glycoprotein IIb/IIIa inhibitors was left to the operator's discretion. Coronary angiography was not performed routinely in the follow-up. RESULTS: Mean age was 67.5 ± 16 years, 75% of the patients were male, 29% had diabetes and 39% had unstable angina. A total of 2.75 ± 1.25 stents were implanted per patient. Bifurcation lesions were identified in 90.1% and the most frequent techniques were the provisional stent in 36% and small crush in 29% of the patients. Intravascular ultrasound was performed in 92.3% of the patients and reinterventions in 21.3% of the stents due to incomplete apposition of the struts after implantation. In the late follow-up, MACE was observed in 15.4% of the patients, cardiac death in 3.6%, target-vessel revascularization in 11.2% and definitive/probably stent thrombosis in 1.4%. CONCLUSIONS: In this study, PCI with DES proved to be safe and effective in the late follow-up of LM lesions, with low cardiac death and stent thrombosis rates.

A leishmaniose cutâneo-mucosa (LM) pode deixar sequelas graves. O diagnóstico precoce evita complicações. OBJETIVO: Avaliar marcadores clínicos para o diagnóstico precoce da LM. MATERIAL E MÉTODO: Estudo de série de 21 casos avaliados com diagnóstico confirmado de LM por meio de entrevista, endoscopia nasal, biópsia e teste cutâneo de Montenegro. RESULTADOS: A cicatriz cutânea ou história de leishmaniose cutânea foram observadas em 8 (38%) pacientes e 13(62%) negaram terem tido forma cutânea e não tinham cicatriz. O início dos sintomas nasais/orais até a definição do diagnóstico variou de 5 meses a 20 anos, média de 6 anos. No teste de Montenegro, o tamanho médio da pápula foi de 14,5mm e não se correlacionou com a duração da doença (p=0,87). O comprometimento nasal predominou e a extensão da lesão não se correlacionou com a duração da doença. Parasitas foram encontrados em 2(9,52%) espécimes de lesões biopsiadas. CONCLUSÃO: O diagnóstico da LM foi tardio. O encontro do parasito na mucosa, a cicatriz típica e leishmaniose cutânea prévia não foram marcadores para o diagnóstico de LM. O diagnóstico de LM pode se basear no teste de Montenegro alterado associado a sintomas nasais e/ou orais e exclusão de outras doenças granulomatosas.

Mucocutaneous Leishmaniasis (ML) can lead to serious sequela; however, early diagnosis can prevent complications. AIM: To evaluate clinical markers for the early diagnosis of ML. MATERIALS AND METHODS: A series study of 21 cases of ML, which were evaluated through clinical interview, nasal endoscopy, biopsy and the Montenegro test. RESULTS: A skin scar and previous diagnosis of cutaneous leishmaniasis (CL) were reported in 8(38%) patients, and 13(62%) of them denied having had previous CL and had no scar. Nasal/oral symptom onset until the ML diagnosis varied from 5 months to 20 years, mean value of 6 years. In the Montenegro test, the average size of the papule was 14.5 mm, which did not correlate with disease duration (p=0.87). The nose was the most often involved site and the extension of the injured mucosa did not correlate with disease duration. The parasite was found in 2 (9.52%) biopsy specimens. CONCLUSIONS: ML diagnosis was late. Finding the parasite in the mucosa, cutaneous scar and/or previous diagnosis of CL were not clinical markers for ML. ML diagnosis must be based on the Montenegro test, chronic nasal and/or oral discharge and histological findings ruling out other granulomatous diseases.

La alimentación al pecho materno es la mejor opción que podemos y debemos ofrecer a los lactantes durante los primeros meses de vida. Se ha perdido la cultura del amamantamiento, de la crianza natural y, posiblemente, el vínculo afectivo natural entre madres e hijos. En Bolivia, la Lactancia Materna (LM) ha sido reimpulsada desde la década de los 90 y nuevamente ocupa un lugar preferente en la atención de los profesionales y trabajadores en salud, así como de importantes grupos de opinión social, medios de comunicación y autoridades de salud. Con el objetivo de determinar los beneficios nutricionales de la LM en menores de 6 meses y el grado de conocimiento materno, se realizaron encuestas a madres con hijos/as hasta los seis meses de edad, nacidos en el Hospital La Paz que acudieron al servicio de pediatría a control de niño sano. De 380 madres encuestadas, el 84% aseguraron conocer la importancia de la lactancia materna pero únicamente el 34% tenía una información clara; en cuanto a la técnica, un 74% sostuvo que la conocía con exactitud pero al ser valoradas, sólo el 22% demostró una técnica adecuada y completa. De todas las madres, 174 (47%) afirmaron que fue un doctor o una enfermera quien les enseñó la técnica de LM. De los/as lactantes, el 58% pertenecían al sexo femenino, el 77 % recibían lactancia materna exclusiva (LME); de aquellos con LME, el 75.5% se encontraban entre los desvíos standart de 0 a +3 de las tablas peso para talla en menores de 6 meses del AEIPI-Nut, mientras que sólo el 53.2% de alimentados con lactancia materna no exclusiva (LMNE) correspondían a estos mismos desvíos y de todos los lactantes el 50% recibía un número adecuado de tomas diarias. Se ha demostrado que aquellos niños/as que reciben lactancia materna exclusiva presentan mejores curvas de crecimiento. El grado de instrucción académica y la edad materna pueden favorecer la capacidad de la mujer para comprender la importancia de la lactancia materna exclusiva en menores de 6 meses. A pesar de los esfuerzos del personal de salud todavía existen dudas acerca de la técnica adecuada de LM. Debemos fomentar la lactancia materna natural exclusiva hasta los 6 meses y seguir capacitando al personal de salud para mejorar el desarrollo y crecimiento de los niños en Bolivia.

The maternal breast feeding is the best option that we can and we must provide to infants during the first months of life. The culture of breast feeding, natural parenting, and possibly the natural emotional link between mothers and children has been lost. In Bolivia, the maternal lactation (LM) has been relaunched since the early 1990s and again occupies pride of place in the attention of professionals and workers in health, as well as large groups of social opinion, media and health authorities. With the aim of determining the nutritional benefits of the LM in children under age of 6 months and the level of maternal awareness surveys were conducted to mothers with children up to six months of age, born in Hospital La Paz who went to the paediatric Centre healthy child control. 380 Surveyed mothers, 84 per cent claimed toknow the importance of breastfeeding, but only 34% had clear information; as to technique, 74% said that it was known exactly but valued, only 22% demonstrated a technique, appropriate and complete. Of all mothers, 174 (47%) claimed that he was a doctor or a nurse who taught the technique of LM. Of the / ACE nursing, 58% were female, 77 per cent were receiving exclusive breastfeeding (LME); those with SCI, the 75.5 per cent were between diversions standart 0 to + 3 of tables weight for height in children under 6 months of the AEIPI-Nut, while that only 53.2% of fed not exclusive breastfeeding (LMNE) corresponded to these same detours and 50% of all infants received an adequate number of shots . It has shown that those children who are exclusively breastfed have better growth curves. The degree of academic instruction and the maternal age may favour women's ability to understand the importance of exclusive breastfeeding among children under age 6 months. Despite the efforts of health workers, there are still doubts about the proper technique of LM. We must encourage natural exclusive breastfeeding up to 6 months and further training of health personnel to improve the development and growth of children in Bolivia.

The present study aimed at investigating the chemical composition of essential oil extracted from Brazilian propolis and the susceptibility of Staphylococcus aureus, Staphylococcus epidermides, Streptococcus pyogenes and Escherichia coli to this substance. The essential oil was obtained by steam distillation of propolis and examined by gas chromatography/mass spectrometry (GC/MS). In addition, the agar diffusion method using filter paper disks was employed. Antibacterial activity was measured as equivalent diameters of inhibition zones (in millimeters) after incubation at 37º C for 24 hours. From the 26 identified constituents, β-caryophyllene (12.7%), acetophenone (12.3%) and β-farnesene (9.2%) were found to be major components. New components, namely linalool, methyl hydrocinnamate, ethyl hydrocinnamate, α-ylangene, γ-elemene and valencene, are reported for the first time to be present in propolis essential oil. This oil also exhibited antibacterial activity.

Eggs and all nymphs of these species were studied employing light microscopy (LM) and scanning electron microscopy (SEM). The major differences observed by LM in the eggs were related to the presence and the distribution of pores on the surface of their chorion. Morphological differences among three nymphal stages (1st, 3rd, and 5th) development of each species were observed. The differential characteristics are chromatic and in the shape of connexival spots. The ultrastructure of the ventral region of the head and the IX, X, and XI abdominal segments (anal tube) of the both species were described demonstrating morphological differences that can be used for diagnosis of the species.