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Resumen Se encontraron individuos de Walterianella inscripta Jacoby (Coleoptera: Chrysomelidae), causando daño al follaje de árboles de Paulownia elongata S.Y. Hu en San Carlos, Pital, Costa Rica. W. inscripta causa rasguños y agujeros que miden entre 0.1 y 0.07 cm2 en el follaje. Observamos una gran incidencia de daño por defoliación que afecta a todos los árboles, con una severidad que en la mayoría de los casos afectó a más del 75% del follaje arbóreo. Este es el primer informe del daño de W. inscripta en P. elongata en Costa Rica.

Abstract We found Walterianella inscripta Jacoby (Coleoptera: Chrysomelidae), causing damage to foliage of Paulownia elongata S.Y. Hu trees in San Carlos, Pital, Costa Rica. W. inscripta causes scratches and holes measuring between 0.1 and 0.07 cm2 in foliage. We observed a great incidence of defoliation damage affecting all trees, with a severity that in most cases affected over 75% of tree foliage. This is the first report of the damage of W. inscripta in P. elongata in Costa Rica.

https://doi.org/10.18845/rfmk.v19i44.6100

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
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Basquiera, Ana L.

; García, Mercedes J

; Martinez Rolón, Juliana

; Olmedo, Julieta

; Laviano, Julia

; Burgos, Rubén

; Caeiro, Gastón

; Remaggi, Guillermina

; Raña, Pablo

; Paoletti, Mariano

; González, Carlos M.

; Fernández, Isolda

; Pavlovsky, Astrid

; Perusini, Maria A.

; Rodriguez, Andrea

; Guanchiale, Luciana

; Carvani, Analia

; Mandrile, Laura

; Figueroa, Flavia

; Vicente Reparaz, Ángeles

; Fragapane Mathus, Patricia N.

; Garate, Gonzalo

; Fauque, María E.

; Kantor, Gustavo

; Cruset, Soledad

; Gonzalez Lorch, Jacqueline S.

; Szelagowski, Milagros

; Giarini, María P.

; Oliveira, Natalia

; García, María C.

; Ventriglia, María V.

; Pereyra, Patricio H.

; Gutierrez, Daniel R.

; Kusminsky, Gustavo

; Troccoli, Josefina

; Freitas, María J.

; Cranco, Santiago

; Del V.Sanchez, Natalia

; Rey, Irene

; Funes, María E.

; Jarchum, Sol

; Freue, Julian

; Miroli, Augusto

; Guerrero, Osvaldo

; López Ares, Lisa

; Campestri, Reinaldo

; Bove, Victor

; Salinas, Graciela N.

; Cabrejo, María

; Milone, Jorge H.

; Zabaljauregui, Soledad

; Gotta, Daniel

; Dupont, Juan Carlos

; Stemmelin, German

Medicina (Buenos Aires)

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aug 2021, Volume 81 N. 4 Pages 536 - 545

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall survival (OS) after COVID-19 infection in pa tients with a hematological disease in Argentina. A completely anonymous survey from the Argentine Society of Hematology was delivered to all the hematologists in Argentina; it started in April 2020. A cut-off to analyze the data was performed in December 2020 and, finally, 419 patients were reported and suitable for the analysis (average age: 58 years, 90% with malignant diseases). After the COVID-19 diagnosis, the 30-day OS for the whole population was 80.2%. From the entire group (419), 101 (24.1%) individuals required intensive care unit admission, where the 30-day OS was 46.6%. Among allogeneic stem cell transplant recipients, the 30-day OS was 70.3%. Factors associated with a low OS were two or more comorbidities, an active hematological disease and history of chemotherapy. In individuals with the three factors, the 30-day OS was 49.6% while the 30-day OS in those without those factors was 100%. Patients with hematological diseases have a higher mortality than the general population. This group represents a challenge and requires careful decision-making of the treatment in order not to compromise the chances of cure.

Resumen El presente estudio tuvo por objetivo primario conocer la mortalidad de pacientes con enfermedad hematológica que presentaron infección por COVID-19 en Argentina. Para ello se difundió una encuesta desde la Sociedad Argentina de Hematología (SAH) entre los hematológos para informar sobre los pacientes con enfermedades hematológicas y diagnóstico de infección por SARS- CoV-2, entre el 19/4/2020, y el 7/12/2020. Se incluyeron individuos de todas las edades con diagnóstico de enfermedad hematológica benigna o maligna e infección por SARS-CoV-2 confirmada por técnica de RT-PCR. Se analizaron 419 pacientes (mediana 58 años; 90% enfermedades malignas). La supervivencia al día 30 fue de 80.2%. La supervivencia fue menor en aquellos que requirieron internación (74.2%), cuidados intensivos (46.6%) y asistencia respiratoria mecánica (36.8%). Entre los trasplantados alogénicos la supervivencia fue 70.3%. Los factores vinculados a la supervivencia global fueron las comorbilidades, el estado de la enfermedad al momento de la infección y el antecedente de quimioterapia. Se pudo establecer un score en el que aquellos que tuvieron un puntaje de 4 alcanzaron una supervivencia del 49.6% al día 30, mientras que la de los pacientes con score 0 fue del 100% a 30 días. En comparación con la población general, los pacientes con enfermedades hematológicas presentan una mayor mortalidad vinculada al COVID-19, motivo por el cual es primordial definir pautas destinadas a disminuir la exposición de los mismos sin comprometer las posibilidades de beneficiarse del tratamiento de la enfermedad de base.

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Common reactions of furfural to scalable process of residual biomass
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Rodriguez, Alejandra

; Rache, Leidy Y.

; Brijaldo, Maria H.

; Silva, Ludmila P. C.

; Esteves, Laura M.

Ciencia en Desarrollo

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jun 2020, Volume 11 N. 1 Pages 63 - 80

Abstract: En | Text: En | PDF: En

Abstract Energy and the environment will always play key roles in society. The climate emergency cannot be ruled out to enable the transition for a clean energy future. Currently, non-renewable energy resources are declining, therefore is important to continuously explore renewable resources. Biomass is a renewable resource that can be applied to reduce climate changes and to accomplish emission policies. Cellulose is the most abundant type of biomass worldwide, which can be transformed into biofuels and potential building block platform molecules (e.g furfural) throughout biological or chemical methods. Furfural can be synthetized from cellulose using hydrolysis and dehydration reactions. Furfural has a furan ring and carbonyl functional group which makes it an important intermediary to produce higher value-added molecules at industrial level. These molecules include gasoline, diesel and jet fuel. However, furfural can also be transformed by hydrogenation, oxidation, decarboxylation and condensation reactions. The selective hydrogenation of furfural produces furfuryl alcohol, an important industrial compound, which is widely employed in the production of resins, fibers, and is considered an essential product for pharmaceutical applications. On the other hand, the oxidation of furfural produces furoic acid which is applied in the agrochemical industry, where it is commonly transformed to furoyl chloride which is finally used in the production of drugs and insecticides. The oxidation and reduction of furfural can carry out through heterogeneous and homogeneous catalysis, and biocatalysis, etc. Selectivity is an important issue in furfural hydrogenation and oxidation reactions since different products can be obtained by using monometallic or bimetallic catalysts and/or different catalyst supports. In biocatalysis approach, different enzymes, complete cells, tools of modern biotechnology, DNA sequencing, regulation of metabolic networks, overexpression of genes that encode enzymes of interest and optimization of the cellular properties of the microorganism are used. To degradate furanic compounds, improving the productivity and selectivity on a target compound. Herein, a review on the current status of furfuryl alcohol and furoic acid production from furfural by heterogeneous catalysis and biocatalysis has been studied. The stability, selectivity and activity of catalysts along with the different furfural oxidation and reduction conditions have been pointed out. Additionally, the main enzymes, microorganisms and mechanism involved in the furfural degradation process have also been discussed.

https://doi.org/10.19053/01217488.v11.n1.2020.10973 338 downloads

ACTIVIDAD ANTIMICROBIANA DE WIRA WIRA Y CERRAJA CONTRA ESTAFILOCOCO, ENTEROCOCO, PSEUDOMONAS Y ESCHERICHIA
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Anaya Muñoz, Santiago Franklin

; Calvo Orellana, Eldy Ericka

; Valdez Ramallo, María Alexandra

; Santa Cruz Rodriguez, Adriana C.

Revista Científica Ciencia Médica

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2020, Volume 23 N. 1 Pages 15 - 21

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Introducción: El uso de plantas con diversos fines etnomedicinales es una práctica ancestral y actualmente común en una vasta parte de la población de Bolivia. Objetivo general: Identificar si la wira wira y cerraja de nuestro medio poseen actividad antimicrobiana contra bacterias patógenas y determinar su toxicidad a través del bioensayo de pruebas biológicas. Materiales y Métodos: Estudio descriptivo; Universo, Wira Wira recolectada del Valle Alto de Cochabamba y Cerraja de Cercado; Muestra, se obtuvo de forma aleatoria un kilogramo de Wira Wira y Cerraja respectivamente; Métodos, se emplearon diferentes técnicas para la extracción de los principios activos, se realizaron pruebas biológicas para determinar la toxicidad de los mismos y se determinó la actividad antimicrobiana por el método de difusión en agar. Resultados: Wira wira demostró actividad antimicrobiana con 4 extractos; alcohólico de tallo, flor y alcohólico agotado de hojas frente a E. faecalis y S. aureus, y acuoso de hojas frente a P. aeruginosa y S. aureus. Por otro lado no se evidencio actividad antibacteriana de los extractos de cerraja. Conclusiones: Wira wira es candidata para estudios posteriores destinados a la identificación del o los compuestos activos puros con actividad antibacteriana, hecho respaldado por los resultados obtenidos en esta y otras investigaciones. Los extractos de cerraja, a diferencia de los resultados obtenidos de otros trabajos, no presentaron actividad antimicrobiana, demostrando la posibilidad y vinculación de la variación en los compuestos de la planta con el ecosistema en el que se desarrolla.

Introduction: The use of plants with various ethnomedicinal purposes is an ancestral practice and currently common in a vast part of the population of Bolivia. General objective: To identify if the extracts of both plants present in our environment have antimicrobial activity against pathogenic bacteria and to determine their toxicity through the bioassay of biological tests. Materials and Methods: Descriptive study; Universe, Wira Wira collected from Valle Alto in Cochabamba and Cerraja collected from Cercado; Sample, we obtained one kilogram of each, Wira Wira and Cerraja randomly; Methods, different techniques were used to extract the active ingredients, biological tests were performed to determine their toxicity and antimicrobial activity was determined by the agar diffusion method. Results: Wira Wira demonstrated antimicrobial activity with 4 extracts; stem alcoholic, flower and alcoholic depleted of leaves against E. faecalis and S. aureus, and aqueous of leaves against P. aeruginosa and S. aureus. On the other hand, there was no evidence of antibacterial activity with the cerraja extracts. Conclusions: Wira Wira is a candidate for further studies aimed at the identification of the pure active compound (s) with antibacterial activity, all this backed up by the positive results in the agar diffusion tests grown with pathogenic bacteria. Unlike the results that demonstrate the antibacterial activity of the Cerraja in research carried out in other parts of the world, it is not the case of the one in our territory, whose extracts did not present any antimicrobial activity, demonstrating the possibility and linking the variation in plant compounds with the ecosystems in which it develops.

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Impact of phosphorus and luminosity in the propagation, photochemical reactions and quality of Lippia alba (Mill.) N.E.Br. seedlings
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Correia Santos, Cleberton

; Franco-Rodriguez, Alejandro

; Araujo, Gonzalo Manuel

; Quintão Scalon, Silvana De Paula

; Do Carmo Vieira, Maria

Revista Colombiana de Ciencias Hortícolas

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aug 2019, Volume 13 N. 2 Pages 291 - 302

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Lippia alba (Mill.) N.E.Br. (hierba de limón) es una especie de interés medicinal y aromática, con estudios incipientes en relación a la nutrición mineral y a la luminosidad en las respuestas foliares y vegetativas. El objetivo del trabajo fue evaluar los aspectos foliares y la producción de plántulas de L. alba bajo dos condiciones de luminosidad (pleno sol y 50% de sombreamiento) y cuatro niveles de fósforo (0, 150, 300 y 450 mg kg-1). Las plántulas presentaron alteraciones en los índices fisiológicos y respuestas fotoquímicas basadas en la fluorescencia de la clorofila-a. La fertilización fosfatada contribuyó en la mitigación del estrés luminoso en la síntesis de clorofilas. La mayor pro ducción de biomasa de las hojas ocurrió con la adición de P. El análisis de componentes principales explicó el 74% de la variabilidad donde fueron características representativas el número de hojas, la fluorescencia inicial y el área foliar específica dentro del componente principal 1 (PC 1) y el número de brotes, supervivencia y el área foliar en el PC 2. En el análisis de conglomerados, se constató la formación de dos grupos, con distancias más bajas entre 300 pleno sol y 450 sombreamiento (2.31). Las plántulas cultivadas a pleno sol presentaron mayor capacidad de supervivencia y calidad. La producción de plántulas de L. alba debe ser realizada bajo pleno sol con adición de 450 mg kg-1 del fósforo.

ABSTRACT Lippia alba (Mill.) N.E.Br. (lemongrass) is a spice and medicinal plant species, with fledgling studies related to mineral nutrition and luminosity on foliar and vegetative responses. Thus, the aim of this study was to assess the foliar aspects and production of L. alba under two light conditions (full sun and 50% shading) and four levels of phosphorus-P (0, 150, 300 and 450 mg kg-1). The L. alba seedlings presented changes in physiological indices and photochemical responses based on chlorophyll-a fluorescence. The phosphate fertilization helped mitigate the light stress for the synthesis of chlorophylls. The greatest leaf biomass production occurred with addition of P. The principal components analysis explained 74% of the variability, with leaf number, initial fluorescence and specific leaf area in principal component 1 (PC 1) and bud number, survival and leaf area in PC 2. Two groups formed in the cluster analysis, with lower distances between P300 full sun and P450 sha ding (2.31). The seedlings cultivated under full sun presented a higher survivability and seedling quality. The production of L. alba seedlings should be done under full sun with the addition of 450 mg kg-1 of phosphorus.

https://doi.org/10.17584/rcch.2019v13i2.9023 127 downloads

Biology of Prodiplosis longifila Gagné and population fluctuation in tomato crops sprayed with insecticides
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Duque, Valentina

; Manzano, Maria R.

; Rodriguez, Erik

Revista Facultad Nacional de Agronomía Medellín

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jan 2018, Volume 71 N. 1 Pages 8351 - 8358

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Se llevaron a cabo estudios de laboratorio para determinar parámetros de historia de vida del mosquito de las agallas Prodiplosis longifila, una plaga clave del tomate. Huevos de P. longifila colectados en cultivos de tomate eclosionaron, en promedio, en 1,2 días y el tiempo de desarrollo (larva I hasta adulto) fue alrededor de 14 días a condiciones ambientales. La proporción de sexos (macho: hembra) de P. longifila fue de 1:1.03. La longevidad promedia del macho y de la hembra (1,1 días ambas) se incrementaron después de consumir azúcar. Ensayos de campo para determinar la fluctuación poblacional de P. longifila se desarrollaron en tres lotes comerciales de tomate en Colombia bajo aspersiones de insecticidas tipo calendario. Los números promedio de larvas en todos los lotes fueron mayores durante las dos últimas semanas que durante las dos primeras semanas de muestreo. El número de larvas aumentó aún bajo la aspersión de insecticidas. El número de larvas aumentó después de la floración, sugiriendo que los adultos fueron atraídos a las flores de tomate y probablemente las utilizaron como fuente de azúcar. La infestación (%) estuvo correlacionada positivamente con el número promedio de larvas/brote foliar, sugiriendo el potencial de este método indirecto para monitorear larvas de P. longifila en tomate. La aspersión de insecticidas en cultivos de tomate para controlar P. longifila en un esquema basado en el calendario no redujo la densidad de larvas.

ABSTRACT Laboratory studies were carried out to determine life history parameters of the bud midge Prodiplosis longifila, a key pest of tomato. P. longifila eggs collected from tomato fields hatched into larvae within 1.2 days average and development time (larva I to adult) was around 14 days at environmental conditions. Sex ratio (male:female) of P. longifila was 1:1.03. Longevity of both male and female P. longifila adults (1.1 days for both of them) increased after sugar feeding. Field trials to determine population fluctuation of P. longifila were conducted in three commercial tomato plots located in Colombia, under calendar-based insecticide treatments. Average numbers of live P. longifila larvae in all plots were higher during the last two weeks of sampling than during the first two. Larvae numbers increased even under insecticide spraying. Larvae numbers increased after flowering, suggesting that adults were attracted to tomato flowers and probably used them as source of sugar. Infestation (%) was positively correlated with average number of larvae/leaf bud, suggesting the potential of this indirect method to monitor P. longifila larvae in tomato. Insecticide sprays, applied to tomato fields to control P. longifila, on a calendar-based regime, did not reduce larvae density.

https://doi.org/10.15446/rfna.v71n1.64262 732 downloads

Mycorrhizal association in gametophytes and sporophytes of the fern Pteris vittata (Pteridaceae) with Glomus intraradices
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Martinez, Alicia E

; Chiocchio, Viviana

; Tai Em, Lo

; Rodriguez, María A

; Godeas, Alicia M

Revista de Biología Tropical

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jun 2012, Volume 60 N. 2 Pages 857 - 865

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Los helechos presentan dos etapas en su ciclo de vida, una fase esporofítica y una gametofítica. Estos por lo general pueden colonizar diferentes ambientes y frecuentemente presentan raíces micorrizadas. Este estudio describe la asociación experimental entre Pteris vittata, un helecho leptosporangiado y una cepa de Glomus intraradices durante el ciclo de vida del helecho, desde la germinación de las esporas hasta el desarrollo del esporofito maduro. El objetivo de este estudio fue comparar los patrones de colonización de G. intraradices a lo largo de todo el ciclo de vida del helecho con los tipos encontrados en la naturaleza. Las esporas maduras fueron obtenidas de frondes fértiles de P. vittata que crecen sobre las paredes de la ciudad de Buenos Aires, Argentina. Las raíces se tiñeron y fueron observadas bajo microscopio óptico para el estudio de la colonización micorrízica. Aproximadamente 75 esporas de helecho se cultivaron en macetas con un sustrato estéril y con un inóculo de G. intraradices (N° 51.331 BAFC) en la superficie. Después de la germinación, se tomaron muestras cada 15 días hasta que se completó el ciclo de vida del helecho. Con el fin de determinar la dinámica de la colonización, cada muestra se observó con el microscopio óptico y el microscopio de confocal luego de la tinción correspondiente. El gametofito fue clasificado como del tipo “Adiantum”. Los gametangios femeninos y masculinos se desarrollaron en la cara inferior del mismo. La micorrización comenzó cuando los gametangios estaban ya diferenciados y la colonización se produjo a través de los rizoides. Las esporas y las vesículas no se encontraron en esta fase del ciclo. La micorrizacion tipo Paris se observó sobre la línea de la nervadura central. El pie del esporofito fue colonizado por el micelio externo. Cuando la raíz se desarrolló, se colonizó “de novo”, y se observó una colonización de tipo Arum. Este estudio demuestra que el tipo de colonización está determinado por la estructura del helecho y no por el hongo. Tanto el gametofito como el pie del embrión tienen crecimiento definido y colonización tipo Paris, mientras que las raíces del esporofito presentan un crecimiento indeterminado y una colonización tipo Arum. Las estructuras que se encontraron bajo cultivo coinciden con las que se encontraron en condiciones naturales.

Ferns, which are usually colonizing different environments and their roots frequently present mycorrhization, have two adult stages in their life cycle, the sporophytic and the gametophytic phase. This paper describes the experimental mycorrhizal association between Pteris vittata leptosporangiate fern and a strain of Glomus intraradices during the life cycle of the fern, from spore germination to the development of a mature sporophyte. The aim of this study was to compare the colonization pattern of in vitro cultures of G. intraradices along the fern life cycle with those found in nature. For this, mature spores were obtained from fertile P. vittata fronds growing in walls of Buenos Aires city, Argentina. Roots were stained and observed under the light microscope for arbuscular mycorrhizal colonization. Approximately, 75 fern spores were cultured in each pot filled with a sterile substrate and G. intraradices (BAFC N° 51.331) as inoculum on the surface. After germination took place, samples were taken every 15 days until the fern cycle was completed. In order to determine colonization dynamics each sample was observed under optical and confocal microscope after staining. Gametophyte was classified as Adiantum type. Male and female gametangia were limited to the lower face, mycorrhizal colonization started when they were differentiated and took place through the rhizoids. Spores and vesicles were not found in this cycle stage. Paris-type mycorrhizal colonization was established in the midrib and in the embrionary foot. It was colonized by external mycelium. When the first root was developed soil inoculum colonized de novo this structure and Arum-type colonization was observed. This study proves that the type of colonization is determined by the structure of the host, not by the fungus. Both the gametophyte and embryo foot have determined growth and Paris-type colonization, while, sporophyte roots have undetermined growth and Arum-type colonization. The structures found in vitro cultures were highly similar to those found under natural conditions. Rev. Biol. Trop. 60 (2): 857-865. Epub 2012 June 01.

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Antígenos de Plasmodium falciparum, blancos de la respuesta inmunitaria humoral en pacientes tratados con cloroquina
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Wide, Albina

; Rangel, María

; Capaldo, Jacinta

; Certad, Gabriela

; Pabón, Rosalba

; Vásquez, Carlos

; Galbán, Neuro

; Zerpa, Noraida

; Rodriguez, Irma

; Magris, Magda

; Noya, Oscar

Boletín de Malariología y Salud Ambiental

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dec 2011, Volume 51 N. 2 Pages 117 - 128

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Se planteó identificar antígenos que pudieran ser reconocidos por los anticuerpos IgG1 e IgG3, descritos como protectores en la infección malárica, en personas con respuesta clínica adecuada (RCA) o falla al tratamiento (FT) antimalárico, provenientes de localidades con diferentes grados de endemicidad. Se evaluaron por Immunoblotting muestras de sueros de individuos provenientes de tres localidades del Edo. Amazonas (Venezuela): Puerto Ayacucho (Atures), San Juan de Manapiare (Manapiare) y Platanal (Alto Orinoco). La reactividad de IgG, IgG1 e IgG3 frente a componentes antigénicos del extracto de P. falciparum (FCB2), permitió identificar un mayor número de moléculas específicas en los pacientes con RCA que en los pacientes con FT. La frecuencia de reconocimiento de polipéptidos fue baja en las tres localidades, algunas moléculas con una frecuencia de reconocimiento igual o mayor al 20% pertenecían a sueros de individuos de las localidades de Puerto Ayacucho y Platanal, ambas con exposición permanente a P. falciparum. Dado el reconocimiento de polipéptidos por IgG, IgG1 e IgG3 en sueros de pacientes con RCA, estos podrían ser considerados como posibles blancos relevantes de la respuesta inmunológica protectora que coadyuven con el tratamiento antimalárico. Esto contribuiría al desarrollo y diseño de vacunas más efectivas, que prevengan la infección malárica y/o potencien la eficacia a la quimioterapia.

Here we studied the presence of antigens recognized by IgG1 and IgG3 antibodies, thought as protective, in patients with adequate clinical response (RCA) or treatment failure (FT), living in areas of different degrees of endemicity. Immunoblotting was evaluated from serum samples of individuals from three locations in the State Amazonas (Venezuela): Puerto Ayacucho (Atures), San Juan de Manapiare (Manapiare) and Pantanal (Alto Orinoco). The reactivity of IgG, IgG1 and IgG3 against antigenic components of the extract of P. falciparum (FCB2) identified a greater number of specific molecules in patients with RCA in patients with AFT. The frequency of recognition of polypeptides was low in all three locations, with some molecules having a recognition rate of greater than or equal to 20% sera of individuals belonging to the towns of Puerto Ayacucho and Platanal, both with cases of P. falciparum. Given the recognition of polypeptides by IgG, IgG1 and IgG3 in sera of patients with RCA, they could be considered as possible targets for relevant protective immune responses that contribute to malaria treatment. This would contribute to the development and design of more effective vaccines that prevent malaria infection and/or enhance the efficacy of chemotherapy.

646 downloads

10.

Ateromatosis de la aorta torácica: su valor como predictora de mortalidad cardiovascular y eventos vasculares cerebrales y coronarios
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Deschle, Hector Alfredo

; Oberti, Pablo

; Lowenstein, Jorge

; Rodriguez Correa, Carlos

; Lanternier, Gastón

; Spina, Salvador

; Falconi, Mariano

; Guevara, Eduardo

; Makhoul, Silvia

; Adaniya, María Elena

Revista argentina de cardiología

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jun 2011, Volume 79 N. 3 Pages 231 - 237

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective To evaluate the severity of atheromatosis of the thoracic aorta and its relation with mortality and cerebrovascular and coronary events. Material and Methods Between 2005 and 2007, 601 patients (ps) were referred for evaluation with transesophageal echocardiography (TEE). Age: 64.53±13.61 years Male gender: 337ps. The following variables were included: Reason for ordering the study: embolic source (37.7%), endocarditis (22.1%), previous to cardioversion (11.5%), mitral valve disease (9.8%), other reasons (18.95%). Risk factors: diabetes, smoking habits, hypertension, dyslipidemia. Presence of atrial fibrillation. The patients were divided into two groups: With uncomplicated aortic plaques < 4 mm: ps = 465. With complex aortic atheromatosis (CAA): aortic plaques ≥ 4 mm, with ulcers, thrombi or aortic debris: ps = 136. Follow-up: 1596 days (mean: 759 days). A total of 520 ps (86.52%) were contacted; the following events were considered: transient ischemic attack or stroke, AMI, angina, revascularization and/or cause of mortality during that period. Multivariate analysis was used to identify independent predictors. A p value < 0.01 was considered statistically significant. Results Cardiovascular mortality: 3.2% (13/407 ps) in group a and 18.6% (21/113 ps) in group b (p<0.01). Combined vascular events: 91/407 ps (22.4%) in group a and 45/113 ps (39.8%) in group b (p<0.01). Multivariate analysis showed that CAA was an independent predictor of cardiovascular mortality (OR 4.54, 95% CI 1.52-13.58, p<0.01) and of cerebrovascular and/or coronary events (OR 3.33, 95% CI 1.66-6.67, p<0.01). Conclusions In this population, CAA was an independent predictor of cardiovascular mortality and combined vascular events.

Objetivo Evaluar la gravedad de la ateromatosis de la aorta torácica y su relación con la mortalidad y los eventos vasculares cerebrales y coronarios. Material y métodos Entre 2005 y 2007 ingresaron prospectivamente 601 pacientes (p) enviados para ecocardiograma transesofágico (ETE). Edad: 64,53±13,61 años. Sexo masculino: 337 p. Se registró: Motivo del estudio: foco embolígeno (37,7%), endocarditis (22,1%), precardioversión (11,5%), valvulopatía mitral (9,8%), otros (18,95%). Factores de riesgo: diabetes, tabaquismo, hipertensión arterial, dislipemia. Presencia de fibrilación auricular. Los p fueron agrupados en: a. Con placas aórticas <4 mm y no complicadas: p = 465. b. Con placas ≥ 4 mm y/o ulceradas, con trombos o debris (ateromatosis aórtica compleja [AAC]): p = 136. Seguimiento: 1596 días (media: 759 días). Se contactaron 520 p (86,52%), considerándose los siguientes eventos: accidente cerebrovascular transitorio o permanente, IAM, angina, revascularización y/o causa de muerte en dicho período. Se utilizó el análisis multivariado para hallar predictores independientes. Se consideró significativa un p < de 0,01. Resultados Mortalidad cardiovascular: 3,2% (13/407 p) en el grupo a y 18,6% (21/113 p) en el grupo b (p < 0,01). Eventos vasculares combinados: 91/407 p (22,4%) en el grupo a y 45/113 p (39,8%) en el grupo b (p < 0,01). En el análisis multivariado, la AAC fue predictora independiente de mortalidad cardiovascular (OR 4,54, 95% IC 1,52-13,58 p < 0,01) y de eventos vasculares cerebrales y/o coronarios (OR 3,33, 95% IC 1,66-6,67 p < 0,01). Conclusión En esta población, la AAC fue predictora independiente de mortalidad cardiovascular y de eventos vasculares combinados.

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11.

Organogenesis from internodal segments of yellow passion fruit
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Biasi, Luiz Antonio

; Falco, Maria Cristina

; Rodriguez, Adriana P. M.

; Mendes, Beatriz M. Januzzi

Scientia Agricola

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dec 2000, Volume 57 N. 4 Pages 661 - 665

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Estudou-se a indução de organogênese em segmentos internodais de maracujá amarelo (Passiflora edulis f. flavicarpa) cultivados em meio contendo 1,0 a 4,0 mg L-1 de benzilaminopurina (BAP). A formação de calo e o desenvolvimento de gemas adventícias foram acompanhados através de microscopia ótica e eletrônica de varredura, que mostrou sua ocorrência simultânea e contínua, com observação de gemas em diversos estádios de desenvolvimento em um mesmo explante. Houve proliferação de calos nas extremidades dos explantes em todos os tratamentos, inclusive no controle. A avaliação dos efeitos do BAP na indução de gemas adventícias mostrou que as concentrações de 1 ou 2 mg L-1 foram mais adequadas. Doses superiores a 2 mg L-1, apesar de eficientes para indução, foram prejudiciais ao crescimento das gemas. Crescimento e enraizamento das gemas adventícias foram obtidos em meio de cultura MS sem reguladores de crescimento e com a concentração de sais reduzida pela metade.

Organogenesis induction from internodal segments of yellow passionfruit (Passiflora edulis f. flavicarpa) was obtained in a medium supplemented with 1.0-4.0 mg L-1 benzylaminopurine (BAP). Callus proliferation and adventitious shoot development were analyzed by light and scanning electron microscopy. Callus proliferation and adventitious shoots were observed simultaneously and continuously, with asynchronous development of shoots in the explants. Proliferation of callus was observed in the explant cut ends in all treatments, including the control. The results show that concentrations of 1.0 or 2.0 mg L-1 BAP gave better rate of organogenesis. Higher concentrations were efficient for the induction of adventitious buds and, were, however, detrimental for subsequent shoot development. Growth and rooting of shoots were obtained in half strength medium without growth regulators.

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