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Shock séptico en niños con bacteriemia por Staphylococcus aureus de la comunidad en un hospital pediátrico de alta complejidad
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Padilla, María Emilia

; Deschutter, Eva Verónica

; Reijtman, Vanesa

; Mastroianni, Alejandra

; García, María Eva

; Bologna, Rosa

; Pérez, Guadalupe

Revista chilena de infectología

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jun 2023, Volume 40 N. 3 Pages 251 - 256

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Background: Available information about risk factors for the development of septic shock is scarce, especially in the pediatric population. Aim: To describe the epidemiological and clinical characteristics of children with community-acquired Staphylococcus aureus bacteremia and to compare the characteristics of children with and without septic shock. Methods: Retrospective cohort study. Inclusion criteria: Children between 30 days and 16 years old, hospitalized in the Juan P. Garrahan Pediatric Hospital between January 2017 and December 2019 for community-acquired infections with S. aureus isolation in blood cultures. Exclusion criteria: History of hospitalization within 3 months prior to admission, living in a closed community, presence of long-term catheter, intraventricular or intraperitoneal devices. Statistical analysis: STATA 16. Results: 142 children were included. 21 children (15%) experienced septic shock. On multivariate analysis, persistent bacteremia (OR 7.15, 95% CI 4.39-23.81, p: 0.001) and secondary focus of infection (OR 6.72, 95% CI 2.02-22.2, p 0.002) were associated with septic shock. The infection-related mortality rate was 3.5% (5 patients). Conclusions: Septic shock was associated with persistent bacteremia and the presence of secondary foci of infection.

Resumen Introducción: La información disponible sobre los factores de riesgo para el desarrollo de shock séptico es escasa, especialmente en población pediátrica. Objetivo: Describir las características epidemiológicas y clínicas de los niños con bacteriemia adquirida en la comunidad por Staphylococcus aureus y comparar las características de los pacientes con y sin shock séptico. Pacientes y Métodos: Estudio de cohorte retrospectivo. Criterios de inclusión: niños entre 30 días y 16 años de edad, internados en el Hospital de Pediatría Juan P. Garrahan entre enero de 2017 y diciembre de 2019 por infecciones adquiridas en la comunidad con desarrollo de S. aureus en hemocultivos. Criterios de exclusión: antecedente de internación dentro de los 3 meses previos al ingreso, vivir en una comunidad cerrada, presencia de catéter de larga permanencia, dispositivos intraventriculares o intraperitoneales. Análisis estadístico: STATA 16. Resultados: Se incluyeron 142 niños. 21 niños (15%) presentaron shock séptico. En el análisis multivariado, se asociaron con shock séptico, la bacteriemia persistente (OR 7,15; IC95% 4,39-23,81; p: 0,001) y el foco secundario de infección (OR 6,72; IC 95% 2,02-22,2; p 0,002). La mortalidad relacionada con la infección fue 3,5% (5 pacientes). Conclusiones: El shock séptico se asoció con la bacteriemia persistente y la presencia de focos secundarios de infección.

https://doi.org/10.4067/s0716-10182023000300251

THERMAL EXCHANGES IN A COVERED LAGOON BIODIGESTER TREATING PIG FARM EFFLUENT HEATED BY SOLAR ENERGY
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Maradini, Priscila da S.

; Rosa, André P.

; Lopes, Juciara O.

; Carlo, Joyce C.

; Borges, Alisson C.

Engenharia Agrícola

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2023, Volume 43 N. spe elocation e20220130

Abstract: En | Text: En | PDF: En

ABSTRACT Covered lagoon biodigesters are widely used in Brazil for treatment of agro-industrial effluents; however, under natural conditions, they operate at temperatures below the ideal. Thus, external sources for heating the effluent can enhance reactor performance and optimize thermal exchanges between the biodigester and the environment. This study aimed to evaluate the thermal exchanges in the internal and external environments of a covered lagoon biodigester from the influence of effluent heating through solar energy. Mathematical modeling (EnergyPlus software) was used as a tool to simulate thermal exchanges and obtain heat transfer rates. To do so, two scenarios were considered: with and without heated effluent. The results showed that solar radiation is the primary source of heating for anaerobic reactors and that the high thermal inertia of the soil contributes to a small variation in temperature of the resident biomass over the course of the day, even in the scenario with heated effluent. The temperature of the resident biomass reached and stabilized at 30°C, even after thermal exchanges with biogas and soil, in both hot and cold periods when heating was applied.

https://doi.org/10.1590/1809-4430-eng.agric.v43nepe20220130/2023

ANAEROBIC CO-DIGESTION OF SWINE AND LAYING HEN WASTE FOR BIOGAS GENERATION AND DIGESTATE QUALITY
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Pereira, Flávia E. de A.

; Rosa, André P.

; Borges, Eduardo S. M.

; Otenio, Marcelo H.

; Souza, Letícia D. de

; Nascimento, Juliana E. L. do

; Borges, Alisson C.

Engenharia Agrícola

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2023, Volume 43 N. spe elocation e20220124

Abstract: En | Text: En | PDF: En

ABSTRACT Anaerobic digestion (AD) stands out as a degradation pathway for the treatment of agro-industrial waste. This study aimed to evaluate the biogas production (Pb) from the co-digestion of swine (SW) and laying hen waste (LHW) under different temperature conditions (psychrophilic x mesophilic). The studies were carried out on a laboratory scale in anaerobic reactors (1.25 L) in a batch system for 60 days. Three mixtures in volumetric proportions (%) of 25/75 (P1), 50/50 (P2), and 75/25 (P3) (SW/LHW) were studied. The mixtures were characterized before and after AD in terms of TS, VS, and COD under temperatures of 18 and 36 °C, with Pb measured daily. Pb was higher at 36 °C for all mixtures compared to the psychrophilic condition (18 °C). Among the mixtures, the highest Pb value was observed for P3, reaching 0.34 and 0.60 m3 biogas kg−1 CODremoved for 18 and 36 °C, respectively. The digestate showed an increase in the contents of micro-and macronutrients for P1, P2, and P3 after AD, which indicates its use for agricultural purposes. The co-digestion of swine and laying hen waste is a promising proposal in terms of management and energy recovery of biogas, especially for mesophilic conditions in mixtures with a predominance of laying hen waste.

https://doi.org/10.1590/1809-4430-eng.agric.v43nepe20220124/2023

Risk of malignancy and diagnostic accuracy of fine-needle aspiration biopsy in thyroid nodules with diameters greater than 4 centimeters
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Barcelos, Rafaela N.

; Camacho, Cléber P.

; Mamone, Maria da Conceição de O. C.

; Ikejiri, Elza S.

; Vanderlei, Felipe A. B.

; Yang, Ji H.

; Padovani, Rosália P.

; Martins, Leandro A. L.

; Biscolla, Rosa Paula M.

; Macellaro, Danielle

; Lindsey, Susan C.

; Maciel, Rui M. B.

; Martins, João Roberto M.

Archives of Endocrinology and Metabolism

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2023, Volume 67 N. 6 elocation e000644

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: The risk of malignancy and diagnostic accuracy of fine-needle aspiration biopsy (FNAB) of thyroid nodules (TN) with diameters ≥ 3-4 cm remains controversial. However, some groups have indicated surgical treatment in these patients regardless of the FNAB results. We aimed to evaluate the diagnostic accuracy of the FNAB in systematically resected ≥4 cm TN and if the risk of malignancy is higher in these patients. Subjects and methods: We retrospectively evaluated 138 patients (142 nodules) with TN with diameters ≥4 cm who underwent thyroidectomy. Results: The FNAB results were nondiagnostic/unsatisfactory (ND/UNS) in 2.1% of the cases and benign in 51.4%. They indicated atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) in 23.9% of cases, follicular neoplasia/suspicious for a follicular neoplasm (FN/SFN) in 9.2%, suspicion of malignancy (SUS) in 8.5%, and malignant in 4.9%. The histopathological analysis after thyroidectomy revealed a thyroid cancer rate of 100% in the FNABs classified as malignant, 33.3% in SUS cases, 7.7% in FN/SFN, 17.6% in AUS/FLUS, and 4.1% in benign FNABs. None of the ND/UNS FNABs were malignant. The global malignancy diagnosis was 14.8% (n = 21). However, the rate of false negatives for FNAB was low (4.1%). Conclusion: We showed that the risk of malignancy in nodules with diameters ≥4 cm was higher compared to the risk of thyroid cancer in TN in general. However, we found a low rate of false-negative cytological results; therefore, our data do not justify the orientation of routine resection for these larger nodules.

https://doi.org/10.20945/2359-3997000000644

Association study between ceftriaxone and a synthetic amide against strains of Pseudomonas aeruginosa
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Rosa, L. L. S.

; Andrade-Júnior, F. P.

; Cordeiro, L. V.

; Souza, H. D. S.

; Athayde-Filho, P. F.

; Gadelha, D. D. A.

; Melo, D. M.

; Silva, D. F.

; Alves, D. N.

; Sobreira, A. L. C.

; Ferreira, S. R. D.

; Teixeira, A. P. C.

; Farias, B. K. S.

; Firmino, R. G.

; Maia, A. K. H. L.

; Lima, E. O.

Brazilian Journal of Biology

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2023, Volume 83 elocation e274149

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Pseudomonas aeruginosa is a non-lactose fermenting Gram-negative bacteria responsible for causing numerous nosocomial infections. The present research aimed to analyze the anti-Pseudomonas aeruginosa potential of 2-Chloro-N-(4-fluoro-3-nitrophenyl)acetamide (A8). The antibacterial potential of A8 was evaluated from the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Association using the checkerboard method. MIC and MBC values were 512 µg/mL for all P. aeruginosa strains evaluated, demonstrating predominantly bactericidal activity. Furthermore, when A8 was associated with the drug ceftriaxone, pharmacological additivity and indifference were evidenced. In this sense, the synthetic amide was interesting, since it demonstrates the potential to become a possible candidate for an antimicrobial drug.

Resumo Pseudomonas aeruginosa é uma bactéria Gram-negativa não fermentadora de lactose, responsável por causar inúmeras infecções nosocomiais. A presente pesquisa teve como objetivo analisar o potencial anti-Pseudomonas aeruginosa da molécula 2-Cloro-N-(4-fluoro-3-nitrofenil)acetamida (A8). O potencial antibacteriano do A8 foi avaliado a partir da Concentração Inibitória Mínima (CIM), Concentração Bactericida Mínima (CBM) e Associação pelo método de checkboard. Os valores de CIM e CBM foram de 512 µg/mL para todas as cepas de P. aeruginosa avaliadas, demonstrando atividade predominantemente bactericida. Além disso, quando o A8 foi associado ao fármaco ceftriaxona, evidenciou-se aditividade e indiferença farmacológica. Nesse sentido, a amida sintética se mostrou interessante, pois demonstra potencial para se tornar um possível candidato a fármaco antimicrobiano.

https://doi.org/10.1590/1519-6984.274149

Silicon as an attenuator of the toxic effects of aluminum in Schinus terebinthifolius plants
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Aguilar, M. V. M.

; Mattos, J. P. O.

; Wertonge, G. S.

; Rosa, F. C. R.

; Lovato, L. R.

; Valsoler, D. V.

; Azevedo, T. D.

; Nicoloso, F. T.

; Tabaldi, L. A.

Brazilian Journal of Biology

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2023, Volume 83 elocation e271301

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Aluminum (Al) is highly toxic to plants, since it causes stress and inhibits plant growth. Silicon (Si) is known to mitigate the stress caused by Al in several plant species. Thus, the current study aims to investigate the soothing effects of Si on morphophysiological and photosynthetic variables, and the attributes associated with oxidative stress in Schinus terebinthifolius plants exposed to Al. Treatments have followed a completely randomized design, with three repetitions based on the following Al/Si combinations (in mM): Treatment 1: 0 Al + 0 Si; Treatment 2: 0 Al + 2.5 Si; Treatment 3: 1.85 Al + 0 Si; Treatment 4: 1.85 Al + 2.5 Si; Treatment 5: 3.71 Al + 0 Si; Treatment 6: 3.71 Al + 2.5 Si. Each sampling unit consisted of a tray with 15 plants, totaling forty-five per treatment. Shoot and root morphological variables, photosynthetic variables, photosynthetic pigments, hydrogen peroxide concentration, lipid peroxidation (MDA), guaiacol peroxidase (POD) and superoxide dismutase (SOD) enzymes, and non-enzymatic antioxidant such as Ascorbic acid (AsA) and non-protein thiol (NPSH) concentration were assessed. Root growth inhibition followed by changes in root morphological variables have negatively affected root and shoot biomass production in plants only subjected to Al. However, adding 2.5 mM Si to the treatment has mitigated the toxic effects caused by 1.85 mM of aluminum on S. terebinthifolius plants.

Resumo O alumínio (Al) é altamente tóxico para as plantas, pois causa estresse e inibe o crescimento vegetal. O silício (Si) é conhecido por atenuar o estresse causado pelo Al em diversas espécies vegetais. Assim, o presente estudo tem como objetivo investigar os efeitos suavizantes do Si sobre variáveis morfofisiológicas e fotossintéticas, e os atributos associados ao estresse oxidativo em plantas de Schinus terebinthifolius expostas ao Al. Os tratamentos seguiram um delineamento inteiramente casualizado, com três repetições baseadas nas seguintes combinações Al/Si (em mM): Tratamento 1: 0 Al + 0 Si; Tratamento 2: 0 Al + 2,5 Si; Tratamento 3: 1,85 Al + 0 Si; Tratamento 4: 1,85 Al + 2,5 Si; Tratamento 5: 3,71 Al + 0 Si; Tratamento 6: 3,71 Al + 2,5 Si. Cada unidade amostral constou de uma bandeja com 15 plantas, totalizando quarenta e cinco plantas por tratamento. Variáveis morfológicas da parte aérea e da raiz, variáveis fotossintéticas, pigmentos fotossintéticos, concentração de peróxido de hidrogênio, peroxidação lipídica (MDA), enzimas guaiacol peroxidase (POD) e superóxido dismutase (SOD) e antioxidantes não enzimáticos como ácido ascórbico (AsA) e grupos tiós não protéicos (NPSH) foram avaliadas. A inibição do crescimento radicular seguida de alterações nas variáveis morfológicas radiculares afetaram negativamente a produção de biomassa radicular e aérea em plantas submetidas apenas ao Al. No entanto, a adição de 2,5 mM de Si ao tratamento atenuou os efeitos tóxicos causados por 1,85 mM de alumínio em plantas de S. terebinthifolius.

https://doi.org/10.1590/1519-6984.271301

Ocean-atmosphere turbulent CO2 fluxes at Drake Passage and Bransfield Strait
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RODRIGUES, CELINA CÂNDIDA F.

; SANTINI, MARCELO F.

; LIMA, LUCIANA S.

; SUTIL, UESLEI ADRIANO

; CARVALHO, JONAS T.

; CABRERA, MYLENE JEAN

; ROSA, ELIANA B.

; BURNS, JACOB W.

; PEZZI, LUCIANO P.

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Suppl. 3 elocation e20220652

Abstract: En | Text: En | PDF: En

Abstract The oceans play an important role in mitigating climate change by acting as large carbon sinks, especially at high latitude regions. The Southern Ocean plays a major role in the global carbon dioxide (CO2) budget. This work aims to investigate the behavior of turbulent CO2 fluxes and quantify it under different atmospheric and oceanic conditions in the Drake Passage and Bransfield Strait regions on high spatiotemporal resolutions when compared with traditional CO2 fluxes estimations. The atmospheric stability condition was used to corroborate the description of CO2 fluxes. In situ, satellite, and reanalysis data from 08 to 22 November 2018, were used in this work. The Bransfield Strait uptaked 38.59% more CO2 than the Drake Passage due to the cold and fresh waters, allied to the influence of glacial meltwater dilution. Which increased the CO2 solubility, directing the CO2 fluxes to the ocean. The Bransfield Strait had predominantly stable atmospheric conditions, which contributed to this region acting as a CO2 sink. The Drake Passage, on average, behaved as a CO2 sink, mainly due to physical characteristics. This research contributes to a better understanding of the Southern Ocean’s role in the global carbon balance on scales that are very difficult to monitor.

https://doi.org/10.1590/0001-3765202320220652

Empatía general y empatía médica en estudiantes mexicanos de medicina: integración de un perfil empático
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Luna, David

; Alcorta-Garza, Adelina

; Moncada-Heredia, Surya

; Miranda-Mercado, Fernando S.

; Urquiza-Flores, Diana I.

; Figuerola-Escoto, Rosa P.

; Lezana-Fernández, Miguel A.

; Meneses-González, Fernando

Cirugía y cirujanos

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aug 2022, Volume 90 N. 4 Pages 517 - 524

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Objective: To identify the association between general empathy and medical empathy. Detect predictors of the level of medical empathy from general empathy. To determine the psychosocial profile that describes the relationship between general empathy, medical empathy, and demographic and academic characteristics in medical students. Method: Descriptive cross-sectional design. Medical students completed the Interpersonal Reactivity Index (IRI) and the Jefferson Scale of Physician Empathy-student version (JSPE-S). Results: Relatively high levels of general and medical empathy were detected. The total score of the IRI and the JSPE-S and their dimensions correlated positively (r = 0.14-0.52), except for the dimension personal distress of the IRI. The score of the IRI dimension empathic concern was the best predictor of the JSPE-S score and its dimensions (b = 0.27-0.54). Four profiles were detected: 1) men, preference for technology-oriented specialty, less empathy; 2) pre-clinical period students, less empathy; 3) students of the clinical period, greater empathy; and 4) women, preference for patient-oriented specialty, greater empathy. Conclusions: General and medical empathy are associated. Differentiated empathic profiles will allow the design of instructional strategies in empathy according to the specific needs of each one.

Resumen Objetivo: Identificar la asociación entre empatía general y empatía médica. Detectar predictores del nivel de empatía médica a partir de la empatía general. Determinar el perfil psicosocial que describa la relación entre empatía general, empatía médica y características demográficas y académicas en estudiantes de medicina. Método: Estudio transversal descriptivo. Estudiantes de medicina completaron el Índice de Reactividad Interpersonal (IRI) y la Escala de Empatía Médica de Jefferson versión estudiantil (EEMJ-E). Resultados: Se detectaron niveles relativamente altos de empatía general y médica. El puntaje total del IRI y la EEMJ-E y sus dimensiones se correlacionaron positivamente (r = 0.14-0.52), excepto para la dimensión malestar personal del IRI. El puntaje en la dimensión preocupación empática del IRI fue el mejor predictor del puntaje de la EEMJ-E y sus dimensiones (b = 0.27-0.54). Se detectaron cuatro perfiles: 1) hombres, preferencia por especialidad orientada a la tecnología, menor empatía; 2) estudiantes del periodo preclínico, menor empatía; 3) estudiantes del periodo clínico, mayor empatía; y 4) mujeres, preferencia por especialidad orientada al paciente, mayor empatía. Conclusiones: La empatía general y la empatía médica se encuentran asociadas. Unos perfiles empáticos diferenciados permitirán el diseño de estrategias de instrucción en empatía acordes con las necesidades específicas de cada uno.

https://doi.org/10.24875/ciru.21000102 443 downloads

Infecciones respiratorias causadas por agentes bacterianos en bovinos y ovinos de la Provincia de Corrientes, Argentina
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Rosa, P. Della

; Sala, J. M.

; Morel, V.

; Gómez, S.

; Caspe, S. G.

Revista veterinaria

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jun 2022, Volume 33 N. 2 Pages 164 - 168

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Mannheimia haemolytica, Trueperella pyogenes and Pasteurella multocida are commensal bacteria of the upper respiratory tract of ruminants. However, in presence of predisposing factors, they can trigger the disease and even lead to death. The objective of this study was to determine the causes of morbidity and mortality in calves and lambs from 4 establishments located in the Province of Corrientes, Argentina. During of the period between June and August 2021, 4 cases of respiratory diseases were received at the INTA Mercedes, Corrientes, Animal Health Laboratory, both in cattle (3) and sheep (1). Incase of cattle, the morbidity in each the herd was 3.3% (5/150), 3.5% (7/200) and 12.4% (56/450). In the sheep flock, the morbidity was 8% (4/50). In sick animals, necropsies were performed and samples of lung and lung abscess were taken. In those samples, bacteriological culture and histological analysis were performed. Bacterial agents including T. pyogenes (1), M. haemolytica (2) and P. multocida (1) were detected, associated with the macroscopic findings and histological lesions. In our study, bacterial agents were detected as causing pneumonia represent in between 2 and 6% of mortality in the herds analyzed, so they should be considered as an important cause of death, in order to implement the necessary corrective and preventive measures.

Resumen Mannheimia haemolytica, Trueperella pyogenes y Pasteurella multocida son bacterias comensales de las vías respiratorias superiores de los rumiantes. Sin embargo, cuando existen factores predisponentes pueden desencadenar enfermedades respiratorias o incluso ocasionar la muerte. El objetivo de este estudio fue determinar las causas de morbilidad y mortalidad en terneros y corderos de 4 establecimientos ubicados en la Provincia de Corrientes, Argentina. Durante los meses de junio a agosto de 2021 se recibieron en el laboratorio de Sanidad Animal del INTA Mercedes, Corrientes, 4 casos de enfermedades respiratorias, tanto en bovinos (3), como en ovinos (1). En el caso de los bovinos, los lotes presentaban una morbilidad de 3,3% (5/150), 3,5% (7/200) y 12,4% (56/450). Por su parte, el lote de ovinos expuestos contó con un 8% (4/50) de animales enfermos. Se realizó la necropsia de los ejemplares, tomando muestras de pulmón y en los casos que estuvieron disponibles, abscesos pulmonares. Con dichas muestras, se realizó el cultivo bacteriológico y análisis histológico. Mediante el cultivo bacteriológico se detectó la acción de T. pyogenes (1), M. haemolytica (2) y P. multocida (1) coincidente con los hallazgos macroscópicos y lesiones histológicas halladas. En nuestro estudio las neumonías por agentes bacterianos representaron entre el 2 y 6% de las causas de mortalidad de los rodeos analizados, por lo que deberían ser tenidas en cuenta como causante de muerte, a fin de implementar las maniobras correctivas y preventivas necesarias.

https://doi.org/10.30972/vet.3326177

10.

Doxazosin adsorption in natural, expanded, and organophilized vermiculite-rich clays
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Rosa, M. S. L.

; Silva, R. A. O.

; Sousa, P. A. A. e

; Nascimento, R. T. do

; Knoerzer, T.

; Santos, M. R. M. C.

Cerâmica

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mar 2022, Volume 68 N. 385 Pages 75 - 83

Abstract: En | Text: En | PDF: En

Abstract Vermiculite clays are adsorbent materials that have good chemical adsorption capacity, which makes them applicable in the removal of drugs from aqueous solutions. Their lamellar structure can be easily expanded and organophilized. To assess the efficacy and environmentally-tolerant capacity of the adsorption method, the organophilized vermiculite clay was compared to both natural and expanded vermiculite clays. To prepare the organophilized clays, a natural clay sample was expanded at 900 °C. The expanded clay was thus treated by immersion in a 1.0 M NaCl solution and organophilized using a cetyltrimethylammonium bromide (CTMA-Br) surfactant, for 24 h at 50 °C. Natural, expanded, and organophilized samples were characterized using the techniques of XRD, FTIR, TG/DSC, and SEM to observe structural changes after expansion and organophilization. These characterizations indicated that there was an increase in the interlamellar space of the expanded and organophilized sample. In addition, a study of the point of zero charge was performed to determine the surface changes of the samples and the amount of doxazosin adsorption in the samples was determined by the time adsorption test. Further, the organophilized sample showed potential adsorption of the drug doxazosin and high performance in relation to the expanded and natural samples.

https://doi.org/10.1590/0366-69132022683853175

11.

Glacial meltwater input to the ocean around the Antarctic Peninsula: forcings and consequences
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LIMA, LUCIANA S.

; PEZZI, LUCIANO P.

; MATA, MAURÍCIO M.

; SANTINI, MARCELO F.

; CARVALHO, JONAS T.

; SUTIL, UESLEI ADRIANO

; CABRERA, MYLENE J.

; ROSA, ELIANA B.

; RODRIGUES, CELINA C.F.

; VEGA, XIMENA A.

Anais da Academia Brasileira de Ciências

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2022, Volume 94 Suppl. 1 elocation e20210811

Abstract: En | Text: En | PDF: En

Abstract The Antarctic region has experienced recent climate and environmental variations due to climate change, such as ice sheets and ice shelves loss, and changes in the production, extension, and thickness of sea-ice. These processes mainly affect the freshwater supply to the Southern Ocean and its water masses formation and export, being crucial to changes in the global climate. Here, we review the influence of the glacial freshwater input on the Antarctic Peninsula adjacent ocean. We highlight each climate process’ relevance on freshwater contribution to the sea and present a current overview of how these processes are being addressed and studied. The increase of freshwater input into the ocean carries several implications on climate, regionally and globally. Due to glacier melting, the intrusion of colder and lighter water into the ocean increases the stratification of the water column, influencing the sea-ice increase and reducing ocean-atmosphere exchanges, affecting the global water cycle. This study shows the role of each hydrological cycle processes and their contributions to the regional oceanography and potentially to climate.

https://doi.org/10.1590/0001-3765202220210811

12.

Impact of internationalization on the working capital requirement of Brazilian companies
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Rosa, Arthur A. S.

; Forti, Cristiano A. B.

; Dias, Vitor F. M. B.

RAM. Revista de Administração Mackenzie

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2022, Volume 23 N. 4 elocation eRAMF220017

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: O objetivo deste estudo foi analisar os efeitos dos períodos de crise na relação entre internacionalização e necessidade de capital de giro (NCG), no período de 2010 a 2018, tendo como amostra as empresas brasileiras de capital aberto. Originalidade/valor: O artigo contribui para a literatura por abordar um tema ainda pouco explorado no que tange à relação entre NCG e internacionalização, além de analisar a influência da crise econômica nessa relação, utilizando, para tanto, três proxies para internacionalização para fins de robustez dos resultados. Design/metodologia/abordagem: Para alcançar o objetivo, usou-se uma regressão pelo método dos momentos generalizado (GMM) com dados em painel. Para isso, foram utilizadas três base de dados para a coleta dos dados: Economatica, Comissão de Valores Mobiliários (CVM) e J. P. Morgan. Resultados: Constatou-se que as empresas brasileiras mais internacionalizadas tendem a ter uma maior NCG e utilizam o estoque como forma de proteção de possíveis imprevistos oriundos de processos de importação. Além disso, a internacionalização se mostra como uma forma de as empresas manterem seu nível de atividade em período de crise nacional.

ABSTRACT Purpose: This study aims to analyze the effects of crisis periods on the relationship between internationalization and the working capital requirement (WCR), from 2010 to 2018, using publicly-traded Brazilian firms as a sample. Originality/value: This paper contributes to the literature by addressing a topic that is still little explored regarding the relationship between WCR and internationalization, as well as analyzing the influence of the economic crisis on this relationship, using, for that, three internationalization proxies for the robustness of the results. Design/methodology/approach: To achieve this goal, a regression by the generalized method of moments (GMM) with panel data was used. For this, three databases were used for data collection: Economatica, Securities and Exchange Commission (Comissão de Valores Mobiliários – CVM), and J. P. Morgan. Findings: More internationalized Brazilian firms tend to have a higher WCR and use stock as a way to protect themselves against possible unforeseen events arising from import processes. In addition, internationalization is shown as a way for firms to maintain their level of activity during national crisis periods.

https://doi.org/10.1590/1678-6971/eramf220017.en

13.

Heart rate variability, thyroid hormone concentration, and neuropsychological responses in Brazilian navy divers: a case report of diving in Antarctic freezing waters
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BRUZZI, RÚBIO S.

; MORAES, MICHELE M.

; MARTINS, YGOR A.T.

; HUDSON, ALEXANDRE S.R.

; LADEIRA, ROBERTO V.P.

; NÚÑEZ-ESPINOSA, CRISTIAN

; WANNER, SAMUEL P.

; ARANTES, ROSA M.E.

Anais da Academia Brasileira de Ciências

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2022, Volume 94 Suppl. 1 elocation e20210501

Abstract: En | Text: En | PDF: En

Abstract Open-water diving in a polar environment is a psychophysiological challenge to the human organism. We evaluated the effect of short-term diving (i.e., 10 min) in Antarctic waters on autonomic cardiac control, thyroid hormone concentration, body temperatures, mood, and neuropsychological responses (working memory and sleepiness). Data collection was carried out at baseline, before, and after diving in four individuals divided into the supporting (n=2) and diving (n=2) groups. In the latter group, autonomic cardiac control (by measuring heart rate variability) was also assessed during diving. Diving decreased thyroid-stimulating hormone (effect size = 1.6) and thyroxine (effect size = 2.1) concentrations; these responses were not observed for the supporting group. Diving also reduced both the parasympathetic (effect size = 2.6) and sympathetic activities to the heart (ES > 3.0). Besides, diving reduced auricular (effect size > 3.0), skin [i.e., hand (effect size = 1.2) and face (effect size = 1.5)] temperatures compared to pre-dive and reduced sleepiness state (effect size = 1.3) compared to basal, without changing performance in the working memory test. In conclusion, short-term diving in icy waters affects the hypothalamic-pituitary-thyroid axis, modulates autonomic cardiac control, and reduces body temperature, which seems to decrease sleepiness.

https://doi.org/10.1590/0001-3765202120210501

14.

Type C botulism outbreak in free-ranging waterfowl in Goiás
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Martins, Andressa S.

; Silva, Tamires A.

; Rosa, Isabella C.C.R.

; Oliveira, Alexia G.F.

; Oliveira, Márcio P.

; Saraiva, Júlia R.

; Dutra, Iveraldo S.

; Borsanelli, Ana Carolina

Pesquisa Veterinária Brasileira

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2022, Volume 42 elocation e07166

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O botulismo é uma doença geralmente fatal, causada pela ingestão de neurotoxinas produzidas pelo Clostridium botulinum. O presente estudo descreve os aspectos epidemiológicos, clínicos e laboratoriais de um surto de botulismo tipo C em aves aquáticas de vida livre habitantes de parque urbano em Quirinópolis, Goiás. De uma população de cerca de 80 aves aquáticas, um total de 30 aves, entre patos (Cairina moschata), marrecos (Anas platyrhynchos) e gansos (Anser cygnoides), morreram no intervalo de 10 dias. Destes, seis aves apresentaram sinais de paralisia flácida de membros pélvicos, pálpebras, pescoço e asas. Para confirmar a suspeita de botulismo, foram analisadas quatro amostras da água do lago, duas amostras da ração consumida pelas aves e amostras de soro, conteúdo intestinal, conteúdo estomacal e fígado de dois marrecos que morreram após apresentarem os sinais clínicos. Pelo bioensaio e neutralização com antitoxina homóloga em camundongos foi possível detectar a presença de toxina botulínica tipo C em uma amostra de água e no conteúdo intestinal de um dos marrecos necropsiados. Adicionalmente, pela reação em cadeia da polimerase identificou-se a presença de C. botulinum tipo C na água do lago. Com base nos sinais clínicos e resultados laboratoriais estabeleceu-se o diagnóstico de botulismo causado pela toxina botulínica tipo C e veiculada provavelmente pela água do lago.

ABSTRACT: Botulism is generally a fatal disease caused by ingestion of neurotoxins produced by Clostridium botulinum. The present study describes the epidemiological, clinical, and laboratory aspects of a type C botulism outbreak in free-living aquatic birds residing in an urban park in Quirinópolis, Goiás, Brazil. Among a population of approximately 80 waterfowl, a total of 30 birds, including ducks (Cairina moschata), teals (Anas platyrhynchos), and geese (Anser cygnoides), died within 10 days. Of these, six birds showed signs of flaccid paralysis of the pelvic limbs, eyelids, neck, and wings. To confirm the suspicion of botulism, four lake water samples, two samples of the feed consumed by the birds, and samples of serum, intestinal content, stomach content, and liver tissue from two teals that died after presenting clinical signs were analyzed. Using bioassay and neutralization with homologous antitoxin in mice, it was possible to detect the presence of botulinum toxin type C in a water sample and in the intestinal content of one of the necropsied teals. Additionally, the presence of C. botulinum type C was identified in the lake water using polymerase chain reaction. Based on the clinical signs and laboratory results, a diagnosis of botulism caused by botulinum toxin type C was confirmed with probable transmission by lake water.

https://doi.org/10.1590/1678-5150-pvb-7166

15.

COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.

; Rocco, Isadora

; Pimentel, Wallace S.

; Pinheiro, Aislan H. B.

; Souza, Paulo M. S.

; Costa, Luiz A. A.

; Teixeira, Marjory M. P.

; Ohashi, Leonardo P.

; Bublitz, Caroline

; Begot, Isis

; Moreira, Rita Simone L

; Hossne Jr, Nelson A.

; Vargas, Guilherme F.

; Branco, João Nelson R.

; Teles, Carlos A.

; Medeiros, Eduardo A. S.

; Sáfadi, Camila

; Rampinelli, Amândio

; Moratelli Neto, Leopoldo

; Rosado, Anderson Rosa

; Mesacasa, Franciele Kuhn

; Capriata, Ismael Escobar

; Segalote, Rodrigo Coelho

; Palmieri, Deborah Louize da Rocha Vianna

; Jardim, Amanda Cristina Mendes

; Vianna, Diego Sarty

; Coutinho, Joaquim Henrique de Souza Aguiar

; Jazbik, João Carlos

; Coutinho, Henrique Madureira da Rocha

; Kikuta, Gustavo

; Almeida, Zely Sant'Anna Marotti de

; Feguri, Gibran Roder

; Lima, Paulo Ruiz Lucio de

; Franco, Anna Carolina

; Borges, Danilo de Cerqueira

; Cruz, Felipe Ramos Honorato De La

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Goraieb, Lilian

; Postigo, Karolyne Barroca Sanches

; Jucá, Fabiano Gonçalves

; Oliveira, Fátima Rosane de Almeida

; Souza, Rafael Bezerra de

; Zilli, Alexandre Cabral

; Mas, Raul Gaston Sanchez

; Bettiati Junior, Luiz Carlos

; Tranchesi, Ricardo

; Bertini Jr, Ayrton

; Franco, Leandro Vieira

; Fernandes, Priscila

; Oliveira, Fabiana

; Moraes Jr, Roberto

; Araújo, Thiago Cavalcanti Vila Nova de

; Braga, Otávio Penna

; Pedrosa Sobrinho, Antônio Cavalcanti

; Teixeira, Roberta Tavares Barreto

; Camboim, Irla Lavor Lucena

; Gomes, Eduardo Nascimento

; Reis, Pedro Horigushi

; Garcia, Luara Piovan

; Scorsioni, Nelson Henrique Goes

; Lago, Roberto

; Guizilini, Solange

Brazilian Journal of Cardiovascular Surgery

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dec 2021, Volume 36 N. 6 Pages 725 - 735

Abstract: En | Text: En | PDF: En

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

https://doi.org/10.21470/1678-9741-2021-0960

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