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ABSTRACT Aim To prepare a consensus document of the cariology contents and competences included in the curriculum for the dentistry degree at Argentine dental faculties/schools Materials and Method Planning the process in stages: Stage 1- Diagnosis of the situation (Google Form) and invitation to participate extended to the 20 academic units (AU) that offer dentistry degrees. Stage 2- Assessment process of Content (C) and Competences (I) agreements in the five domains: D1 Basic Sciences, D2 Risk and diagnosis of dental caries, D3 Decision-making for non-invasive treatments, D4 Decision-making for invasive treatment, and D5 Evidence-based cariology at community level. Stage 3- Consensus. Stages 2 and 3 were held in Workshop format in virtual mode (W) Results Stage 1- Of the total 20 Google forms sent to the AU, 13 responses were received: 7 from National Universities and 6 from Private Universities. All participants agreed to be part of the consensus. Stage 2- W: 20 representatives from 10 AU participated. It began with a contextualizing conference, after which the representatives were divided into 5 groups to assess the agreements of each D. Stage 3- The Cariology Curriculum document was organized into 5 Domains, and 23 C and 31 I of clinical application were defined for teaching cariology. The contents and competences for each domain were agreed upon. The final document was sent to all W participants for their approval and dissemination in each AU involved Conclusion Cariology contents were defined for dentistry students at Universities in the Argentine Republic.

RESUMEN Objetivo Elaborar un documento de consenso de los contenidos y competencias de cariología en el currículo para las facultades/escuelas de odontología argentinas, a nivel del grado Materiales y Método El proceso de creación se efectuó en etapas: 1- Diagnóstico de situación (Formulario electrónico) e invitación a participar a las 20 unidades académicas (UA) donde se imparte la carrera de odontología. 2- Proceso de valoración de acuerdos de Contenidos (C) y Competencias (I) en los cinco dominios (D): D1: Ciencias Básicas; D2: Riesgo y diagnóstico de caries dental; D3: Toma de decisiones tratamientos no invasivos; D4: Toma de decisiones para el tratamiento invasivo y D5: Cariología basada en la evidencia a nivel comunitario. 3- Etapa de consenso. Las etapas 2 y 3 se efectuaron en formato de Workshop en modalidad virtual (W) Resultados Etapa 1: Del total de 20 formularios enviados a las UA se recibieron 13 respuestas (65%), 7 (53,8%) de Universidades Nacionales y 6 (46,1%) de gestión Privada. El 100% de los participantes estuvieron de acuerdo en formar parte del consenso. Etapa 2: W: Participaron 20 representantes de 10 UA. El proceso se inició con una conferencia contextualizadora, posteriormente los representantes fueron divididos en 5 grupos para la valoración de acuerdos de cada D. Etapa 3: El documento de658. 658.l Currículo en Cariología se organizó en 5 Dominios. Se definieron 23 C y 31 I de aplicación clínica para la enseñanza de la Cariología. Se consensuaron los contenidos y las competencias para cada uno de los dominios. El documento final fue enviado a todos los participantes del W para su aprobación y difusión en cada una de las UA involucradas Conclusión En base al trabajo realizado se determinó un consenso de competencias y contenidos en cariología para estudiantes de grado de Odontología, de las Universidades de la República Argentina.

https://doi.org/10.54589/aol.36/3/183

Presentación clínica de patologías no malignas que (y simulan leucemia cutis: a propósito de dos casos
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Sotelo, Catrian

; Cervini, Andrea B.

; Cella, Eliana

; Galluzzo, María L

; Rossi, Jorge

; Rubio, Patricia

; Felice, María S.

Archivos argentinos de pediatría

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nov 2023, Volume 121 N. 5 Pages 16 - 16

Abstract: Es | Text: Es | PDF: Es

RESUMEN La infiltración cutánea por células leucémicas conocida como leucemia cutis es una presentación infrecuente de esta patología y constituye un desafío diagnóstico. Los diagnósticos como infecciones, otras patologías neoplásicas con afectación cutánea y los trastornos histiocíticos, entre otros, constituyen los principales diagnósticos diferenciales, ya que configuran un escenario pronóstico y terapéutico diferente. Se presentan dos pacientes que fueron diagnosticados inicialmente como leucemia cutis, cuyo diagnóstico final fue de patologías no malignas.

https://doi.org/10.5546/aap.2022-02796

Production of dental prosthetics in the SUS in Brazilian older population and impact of the covid-19 pandemic
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Vieira, Manuella Fluck

; Marques, Patrícia Schunck Alferes

; Figueiredo, Daniela de Rossi

; Carcereri, Daniela Lemos

; Cascaes, Andreia Morales

Revista de Saúde Pública

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2023, Volume 57 elocation 51

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Descrever as tendências na produção de próteses odontológicas pelo Sistema Único de Saúde (SUS) em idosos de 60 anos ou mais no Brasil e nas regiões do país de 2010 a 2019, e o impacto da pandemia de covid-19 na produção esperada para 2020 e 2021. MÉTODOS Estudo de séries temporais que utilizou dados secundários provenientes do banco de dados do SUS (Datasus–Tabnet), e do Instituto Brasileiro de Geografia e Estatística, no período de 2010 a 2021. Calcularam-se as taxas padronizadas por idade para o Brasil e regiões de cada ano analisado. Regressões lineares generalizadas, pelo método de estimação de Prais-Winstein, estimaram as tendências das produções. RESULTADOS Houve tendência de crescimento na taxa padronizada de produção das próteses totais e das demais próteses para cada 100 mil habitantes, no Brasil e em todas as regiões do país. O aumento na produção de próteses totais foi maior na região Nordeste (50,3%/ano) e menor na região Norte (19,1%/ano). As tendências na produção das demais próteses foram maiores na região Sudeste (120,7%/ano) e menores na região Norte (24,5%/ano). A produção de próteses para ambos os grupos diminuiu nos anos de pandemia. Em 2020, a diferença relativa variou de -36,4% (Norte) até -61,7% (Nordeste) para a produção de próteses totais e de -17,9% (Norte) até -68,4% (Nordeste) para as demais próteses. Em 2021, as taxas padronizadas e a produção absoluta aumentaram quando comparadas ao ano anterior, todavia, em relação aos valores esperados, as diferenças foram próximas às encontradas em 2020. CONCLUSÃO Políticas voltadas para a produção de próteses totais e das demais próteses vêm tomando forças e crescendo. Todavia, a produção se mantém distante da necessidade da população e não há equidade na oferta dos serviços. A pandemia de covid-19 impactou negativamente na produção de próteses dentárias pelo SUS.

ABSTRACT OBJECTIVE Describe the trends in the production of dental prosthetics by the Unified Health System (SUS) in older people aged 60 years or older in Brazil and country regions from 2010 to 2019 and the impact of the covid-19 pandemic on the expected production for 2020 and 2021. METHODS A time series study using secondary data from the SUS database (Datasus-Tabnet) and the Instituto Brasileiro de Geografia e Estatística (Brazilian Institute of Geography and Statistics - IBGE) from 2010 to 2021. Age-standardized rates were calculated for Brazil and regions for each year analyzed. Generalized linear regressions estimated production trends using the Prais-Winstein estimation method. RESULTS A growth trend occurred in the standardized production rate of complete dentures and other prosthetics per 100,000 inhabitants in Brazil and all country regions. The increase in the production of complete dentures was higher in the Northeast region (50.3%/year) and lower in the North region (19.1%/year). Trends in the production of other prosthetics were higher in the Southeast region (120.7%/year) and lower in the North region (24.5%/year). The output of prosthetics for both groups decreased in the pandemic years. In 2020, the relative difference ranged from -36.4% (North) to -61.7% (Northeast) for producing complete dentures and from -17.9% (North) to -68.4% (Northeast) for other prosthetics. In 2021, standardized rates and total production increased compared to the previous year. However, compared with expected values, the differences were close to those in 2020. CONCLUSION Policies aimed at producing complete dentures and other prosthetics have been increasing. However, production remains far from the population’s needs, and there is no equity in providing services. The covid-19 pandemic negatively impacted the production of dental prosthetics by SUS.

https://doi.org/10.11606/s1518-8787.2023057004828

Strengthening public health policies for childhood cancer: Peru’s achievements through the WHO Global Initiative for Childhood Cancer
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Maradiegue, Essy

; Pascual, Claudia

; Vasquez, Liliana

; Maza, Ivan

; Ugaz, Cecilia

; Montoya, Jackeline

; Zapata, Arturo

; García, Henry

; Chavez, Sharon

; Ordoñez, Katy

; Rossi, Jonathan

; Diaz, Rosdali

; Morales, Roxana

; Trigoso, Viviana

; Ames, Romy

; Celis, Edinho

; Barzola, Isela

; Torres, Liliana

; Cosme, Melitta

; Tarrillo, Fanny

; Rojas, Ninoska

; Santillan, Carlos

; Quispe, Yuly

; Palacios, Víctor

; Godoy, Victoria

; Tello, Mariela

; Tarco, Duniska

; Wachtel, Antonio

; Malaver, Estela

; Diaz, Elizabeth

; Goyburu, Marlene

; Perez, Vivian

; Talavera, Ivy

; Baca, Maria Edith

; Maza, Mauricio

; Saldaña, Lily

; Holguin, Alexis

; Jarquin, Marta

; Loggetto, Patricia

; Metzger, Monika

; Friedrich, Paola

; Lam, Cath

; Rodriguez Galindo, Carlos

Revista Panamericana de Salud Pública

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2023, Volume 47 elocation e132

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

RESUMO Objetivo. Relatar o progresso, desde junho de 2019, da implementação da Iniciativa Global da Organização Mundial da Saúde para o Câncer Infantil no Peru, no âmbito do marco CureAll, que pode ser replicado em países de baixa e média renda. Método. Foi utilizado um método misto de avaliação participativa e documental. A avaliação participativa incluiu interessados diretos de diferentes instituições governamentais, organizações sem fins lucrativos e parceiros internacionais. O aspecto documental consistiu em uma revisão de dados sobre o ambiente regulatório, projetos nacionais e intervenções implementadas. O Ministério da Saúde do Peru contou com mais de 150 participantes para a formação de comitês de trabalho, que elaboraram políticas e documentos normativos para fortalecer os serviços de atenção primária à saúde. Resultados. Entre os resultados alcançados estão a redução da taxa nacional de abandono do tratamento, de 18,6% para 8,5%, a aprovação da Lei do Câncer Infantil, melhorias no manejo de pacientes com neutropenia febril e redução nas taxas de deterioração clínica e mortalidade de pacientes hospitalizados. A implementação do CureAll permite que as equipes locais adotem estratégias específicas e monitorem os resultados iniciais em oncologia pediátrica. Conclusões. Os resultados obtidos refletem o trabalho em equipe, a liderança das autoridades, o suporte técnico dos profissionais e o apoio das organizações envolvidas. Serão necessárias mais ações para garantir a sustentabilidade, além de ferramentas de monitoramento para assegurar o sucesso das atividades planejadas.

RESUMEN Objetivo. Informar sobre los avances de Perú en el periodo transcurrido a partir de junio del 2019, en relación con la puesta en práctica de la Iniciativa Global de la Organización Mundial de la Salud contra el Cáncer Infantil utilizando el marco CureAll, que es posible replicar en los países de ingresos bajos y medianos. Métodos. Se utilizó un método mixto de evaluación participativa y documental. En la evaluación participativa intervinieron las partes interesadas de diversas instituciones gubernamentales, organizaciones sin fines de lucro y asociados internacionales. El aspecto documental consistió en un examen de los datos sobre el entorno regulatorio, los proyectos nacionales y las intervenciones llevadas a cabo. El Ministerio de Salud involucró a más de 150 participantes que formaron los comités de trabajo que han elaborado documentos normativos y regulatorios a fin de reforzar los servicios de asistencia. Resultados. Entre los logros cabe citar la disminución del 18,6% al 8,5% de la tasa nacional de abandono del tratamiento, la aprobación de la Ley de Cáncer Infantil, las mejoras en el tratamiento de los pacientes con neutropenia febril y la reducción de las tasas de episodios de deterioro clínico y de mortalidad en los pacientes hospitalizados. El marco de aplicación de CureAll permite que los equipos locales pongan en práctica estrategias específicas y realicen un seguimiento de los resultados iniciales en el ámbito de la oncología pediátrica. Conclusiones. Los resultados obtenidos reflejan el trabajo en equipo, el liderazgo de las autoridades, el respaldo técnico de los profesionales y el apoyo de las organizaciones implicadas. En el futuro, será necesario adoptar nuevas medidas para asegurar su viabilidad, y será preciso contar con herramientas de seguimiento para garantizar el éxito de las actividades planificadas.

ABSTRACT Objective. To report the progress in Peru, since June 2019, in the implementation of the World Health Organization Global Initiative for Childhood Cancer using the CureAll framework, which can be replicated in low- and middle-income countries. Methods. A mixed method was used of participatory and documentary evaluation. The participatory evaluation included stakeholders from various government institutions, nonprofit organizations, and international partners. The documentary aspect consisted of a review of data on the regulatory environment, national projects, and interventions implemented. The Ministry of Health engaged more than 150 participants to form working committees, which have developed policy and regulatory documents to strengthen care services. Results. Achievements include a decrease in the national treatment abandonment rate from 18.6% to 8.5%, the approval of the Childhood Cancer Law, improvements in the management of patients with febrile neutropenia, and a reduction in rates of events of clinical deterioration and mortality of hospitalized patients. The Cure All implementation framework allows local teams to implement specific strategies and monitor early outcomes in pediatric oncology. Conclusions. The results obtained reflect the teamwork, the leadership of the authorities, the technical support of professionals, and the support of involved organizations. Further actions will be needed to guarantee sustainability, and monitoring tools are needed to assure success in the planned activities.

https://doi.org/10.26633/rpsp.2023.132

Updated Anopheles mosquitos abundance and distribution in north-eastern malaria-free area of Argentina
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STEIN, MARINA

; MARTIN, MÍA E.

; RAMÍREZ, PATRICIA G.

; ETCHEPARE, EDUARDO G.

; ORIA, GRISELDA I.

; ROSSI, GUSTAVO C.

; KURUC, JORGE

; ESTALLO, ELIZABET L.

Anais da Academia Brasileira de Ciências

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2023, Volume 95 Suppl. 2 elocation e20220956

Abstract: En | Text: En | PDF: En

Abstract Malaria is the most important parasitic disease worldwide. In 2019, more than 679,441 cases of malaria were reported in the American region. During this study, Argentina was in malaria pre-elimination autochthonous transmission phase with the aim of being declared as malaria-free country. The aim of this work was to assess the influence of remote sensing spectral indices (NDVI, NDWI) and climatic variables (temperature, relative humidity and precipitation) on the distribution and abundance of Anopheles mosquitoes, in four localities with different degrees of anthropogenic disturbance and with previous malaria cases records located , in a historical malarious area in northeastern of Argentina. Between June 2012 and July 2014, mosquitoes were collected. We collected 535 Anopheles adult mosquitoes. Anopheles strodei s.l. was the most abundant species. The greatest richness, diversity and abundance of species were registered in wild and semi-urban environments. The abundance of Anopheles presented a negative association with relative humidity and mean temperature, but positive with mean maximum temperature. The most important variables determining Anopheles total abundance and distribution were NDWI Index and distance to vegetation. The abundance of An. strodei s.l., was positive associated with water areas whereas the NDVI Index was negatively associated.

https://doi.org/10.1590/0001-3765202320220956

Effects of autolyzed yeast on leukocyte oxidative metabolism and pneumonia occurrence in feedlot steers
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Garbossa, Gabriela

; Delarezi, Dailis

; Rossi, Patrícia S.

; Thomaz, Gabriela R.

; Flores, Gabriel B.

; Horner, Willi

; Neumann, Mikael

; Peres, Jayme A.

; Bertagnon, Heloísa G.

Pesquisa Veterinária Brasileira

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2023, Volume 43 elocation e07066

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: Although yeast supplementation has shown an immunostimulant effect in feedlot cattle, the question remains whether it influences the occurrence of the bovine respiratory disease complex (BRD) in feedlot cattle. Therefore, our objective was to evaluate whether dietary supplementation with autolyzed yeast affects the efficiency of blood phagocytes, reducing inflammation and the occurrence of BRD in feedlot cattle. A randomized experimental trial was conducted with whole steers with half Angus blood for 106 days: control (n=10): diet without yeast; Y4 (n=12): yeast diet (4g per animal per day); and Y7 (n=7): yeast diet (7g per animal per day). On Days 0, 14, 42, 70, and 105, blood count, leukocyte oxidative metabolism, serum haptoglobin, frequency of nasal secretion and orbital temperature were evaluated. On slaughter day, a lung evaluation was performed. On Days 42 and 70 of feedlot finishing, the treated animals showed increased leukocyte oxidative metabolism (D42 P=0.04; D70 P=0.02) compared to the control group. These animals had a lower frequency of mucopurulent nasal secretion, lower orbital temperature and reduced pneumonia occurrence than the treated groups (P=0.05) with less lung lesion severity (P=0.01), allowing us to infer that the autolyzed yeast improves blood phagocytic function and decreases the inflammation and BRD of feedlot steers, especially at a dose of 4g.

RESUMO: Embora a suplementação com leveduras tenha demonstrado efeito imunoestimulante em bovinos, permanece-se a dúvida se ela influencia na ocorrência do complexo doença respiratória bovina (CDRB) em bovinos confinados. Portanto, objetivou-se avaliar se a suplementação dietética com levedura autolisada influencia a eficiência de fagócitos sanguíneos, reduzindo inflamações e a ocorrência de CDRB em bovinos confinados. Realizou-se um ensaio experimental randomizado com 36 novilhos inteiros 1/2 sangue Angus por 106 dias: controle (n=10): dieta sem levedura; Y4 (n=12): dieta com levedura (4g por animal por dia); e Y7 (n=7): dieta com levedura (7g por animal por dia). Nos dias 0, 14, 42, 70 e 105, hemograma, metabolismo oxidativo de leucócitos, haptoglobina sérica, frequência de secreção nasal e temperatura orbital foram avaliados. No dia do abate, foi realizada avaliação pulmonar. Nos dias 42, e 70 de terminação em confinamento, os animais tratados apresentaram aumento do metabolismo oxidativo dos leucócitos (D42 P=0,04; D70 P=0,02) em relação ao grupo controle. Esses animais apresentaram menor frequência de secreção nasal mucopurulenta, menor temperatura orbital, menor ocorrência de pneumonias (P=0,05) com menor gravidade das lesões pulmonares (P=0,01), permitindo inferir que a levedura autolisada na dieta melhorou a eficiência dos fagócitos sanguíneos, reduzindo inflamações e a ocorrência de CDRB, especialmente na dosagem de 4g.

https://doi.org/10.1590/1678-5150-pvb-7066

Factors associated with demand for emergency medical services by people with hypertension and diabetes
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Ferreira, Patrícia Chatalov

; Marcon, Sonia Silva

; Teston, Elen Ferraz

; Vieira, Viviane Cazetta de Lima

; Souza, Rebeca Rosa de

; Lopes, Mislaine Casagrande de Lima

; Marquete, Verônica Francisqueti

; Rossi, Robson Marcelo

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 2 elocation e20220147

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to analyze the association between recurrence of emergency service visits due to lack of blood pressure and/or glycemic control with sociodemographic variables and disease registration in Primary Care. Methods: quantitative study, which consulted medical records of people who attended these services two or more times for 26 months. Descriptive statistics and multiple logistic regression models were used in analysis. Results: most people did not have hypertension and/or diabetes record in their Primary Care records. The absence of this record was more frequent in males, aged between 18 and 59 years, with low education and lack of blood pressure. There was association between greater number of people seeking these services in the same year and not monitoring the chronic condition in specialized care. Conclusions: people who do not follow up hypertension and/or diabetes in Primary Care are more likely to need assistance due to blood pressure and/or glycemic management.

RESUMEN Objetivos: analizar la asociación entre la recurrencia de visitas a los servicios de emergencia por falta de control de la presión arterial y/o glucemia con variables sociodemográficas y registro de la enfermedad en Atención Primaria. Métodos: estudio cuantitativo, que consultó las historias clínicas de las personas que acudieron a estos servicios dos o más veces en un período de 26 meses. En el análisis se utilizaron estadísticas descriptivas y modelos de regresión logística múltiple. Resultados: la mayoría de las personas no tenían registro de hipertensión y/o diabetes en sus registros de Atención Primaria. La ausencia de este registro fue más frecuente en el sexo masculino, con edad entre 18 y 59 años, con baja escolaridad y falta de presión arterial. Hubo asociación entre mayor número de personas que buscaban estos servicios en el mismo año y no seguimiento de la condición crónica en atención especializada. Conclusiones: las personas que no tienen seguimiento de hipertensión y/o diabetes en Atención Primaria tienen más probabilidad de necesitar asistencia por control de la presión arterial y/o glucemia.

RESUMO Objetivos: analisar a associação entre a recorrência de atendimentos nos serviços de emergência devido ao descontrole pressórico e/ou glicêmico com as variáveis sociodemográficas e cadastro da doença na Atenção Primária. Métodos: estudo quantitativo, que consultou prontuários de pessoas que compareceram duas ou mais vezes nesses serviços no período de 26 meses. Utilizaram-se estatística descritiva e modelos de regressão logística múltipla na análise. Resultados: a maioria das pessoas não possuía registro/cadastro de hipertensão e/ou diabetes no prontuário da Atenção Primária. A ausência desse cadastro foi mais frequente em pessoas do sexo masculino, com idade entre 18 e 59 anos, baixa escolaridade e descontrole pressórico. Observou-se associação entre número maior de procura desses serviços em um mesmo ano e não acompanhamento da condição crônica na assistência especializada. Conclusões: pessoas que não fazem acompanhamento da hipertensão e/ou diabetes na Atenção Primária estão mais sujeitas a necessitar de assistência por descontrole pressórico e/ou glicêmico.

https://doi.org/10.1590/0034-7167-2022-0147

FATORES ASSOCIADOS A NÃO ADESÃO TERAPÊUTICA EM PESSOAS COM HIPERTENSÃO QUE PROCURARAM ASSISTÊNCIA POR EMERGÊNCIA
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Ferreira, Patrícia Chatalov

; Teston, Elen Ferraz

; Carvalho, Brígida Gimenez

; Silva, Joice Lourenço da

; Reis, Pamela dos

; Rossi, Robson Marcelo

; Marcon, Sonia Silva

Cogitare Enfermagem

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2023, Volume 28 elocation e86141

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: to analyze factors associated with therapeutic non-adherence among individuals with Arterial Hypertension who seek emergency care and/or assistance due to hypertensive complications. Method: this is a cross-sectional study conducted from December 2019 to October 2020 with 238 people living in a medium-sized municipality from southern Brazil using Morisky’s 8-Item Medication Adherence Scale. Multiple Logistic Regression was used in the analysis. Results: a total of 86 (36.1%) participants were considered as non-adherent. A higher change of non-adherence was observed in people younger than 60 years of age (Odds Ratio=2.04), who sought emergency services in the three years under study (Odds Ratio=5.08), and who had a bond with Primary Health Care professionals (Odds Ratio=1.96). Conclusion: acknowledging the factors associated with non-adherence to the therapy will allow professionals to conduct educational interventions and assist people with hypertension according to their needs, thus preventing/postponing complications.

RESUMEN Objetivo: analizar factores asociados a la no adhesión a la terapia en personas con Hipertensión Arterial que asisten a servicios de urgencia por emergencias y/o complicaciones derivadas de la hipertensión. Método: estudio transversal realizado entre diciembre de 2019 y octubre de 2020 con 238 residentes en un municipio de mediano porte del sur de Brasil, utilizando la Escala de Adherencia Terapéutica de 8 ítems de Morisky. En el análisis se utilizó Regresión Logística Múltiple. Resultados: se consideró que 86 (36,1%) participantes no cumplían con la terapia. Se observó una mayor probabilidad de no adhesión en personas menores de 60 años (Odds Ratio=2,04), que buscaron asistencia en los servicios de urgencia en los tres años en estudio (Odds Ratio=5,08) y que tenían una relación con profesionales de Atención Primaria de la Salud (Odds Ratio=1,96). Conclusión: reconocer los factores asociados a la no adhesión a la terapia permitirá que los profesionales realicen intervenciones educativas y asistan a las personas con hipertensión arterial según sus necesidades, previniendo/posponiendo complicaciones.

RESUMO: Objetivo: analisar fatores associados à não adesão terapêutica em pessoas com Hipertensão Arterial que procuraram serviços de pronto atendimento por emergência e/ou complicação hipertensiva. Método: estudo transversal realizado entre dezembro de 2019 a outubro de 2020, com 238 pessoas residentes em um município de médio porte do Sul do Brasil, mediante aplicação da Escala de Adesão Terapêutica de Oito Itens de Morisky. Na análise se utilizou Regressão Logística Múltipla. Resultados: 86 (36,1%) participantes foram considerados não aderentes. Foi observada maior chance de não adesão em pessoas com menos de 60 anos (Odds Ratio=2,04), que buscaram assistência nos serviços de pronto atendimento nos três anos em estudo (Odds Ratio=5,08) e que tinham vínculo com profissionais da Atenção Primária à Saúde (Odds Ratio=1,96). Conclusão: reconhecer os fatores associados com a não adesão à terapêutica possibilitará aos profissionais realizar intervenções educativas e assistir as pessoas com hipertensão de acordo com suas necessidades, prevenindo/postergando complicações.

https://doi.org/10.1590/ce.v28i0.86141

Production of dental prosthetics in the SUS in Brazilian older population and impact of the covid-19 pandemic
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Vieira, Manuella Fluck

; Marques, Patrícia Schunck Alferes

; Figueiredo, Daniela de Rossi

; Carcereri, Daniela Lemos

; Cascaes, Andreia Morales

Revista de Saúde Pública

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2023, Volume 57 elocation 51

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.11606/s1518-8787.2023057004828

10.

The drop plate method as an alternative for Azospirillum spp viable cell enumeration within the consensus protocol of the REDCAI network
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Salvo, Luciana P. Di

; García, Julia E.

; Puente, Mariana L.

; Amigo, Josefina

; Anríquez, Analía

; Barlocco, Claudia

; Benintende, Silvia

; Bochatay, Tatiana

; Bortolato, Marta

; Cassán, Fabricio

; Castaño, Carolina

; Catafesta, Melina

; Coniglio, Anahí

; Díaz, Marisa

; Galián, Liliana R.

; Gallace, Eugenia

; García, Patricia

; Salamone, Inés E. García de

; Landa, Marianela

; Liernur, Germán

; Maneiro, María Laura

; Massa, Rosana

; Malinverni, Julieta

; Marchessi, Nicolás

; Monteleone, Emilia

; Oviedo, Silvina

; Pobliti, Lucrecia

; Portela, Gabriela

; Radovancich, Débora

; Righes, Silvia

; Rocha, Rosina

; Cáceres, Enrique Rodríguez

; Rossi, Alejandro

; Santella, Gisela

; Tortora, María Laura

; Trejo, Nora

; Valenzuela, José A.

; Vallejo, Daniela

Revista argentina de microbiología

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jun 2022, Volume 54 N. 2 Pages 61 - 70

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La evaluación de la calidad de los inoculantes comerciales es fundamental para garantizar una adecuada respuesta de los cultivos a la inoculación dentro de un marco de bioseguridad. En este sentido, el objetivo de este trabajo fue la estandarización y validación de la técnica de la microgota para la cuantificación de Azospirillum como metodología alternativa a la técnica de siembra en superficie, propuesta actualmente en el protocolo consenso de la Red de Calidad de Inoculantes, REDCAI. Entre 14 y 25 laboratorios, tanto privados como públicos, participaron de tres ensayos independientes. A partir de ellos se obtuvieron resultados reproducibles y robustos que permiten confirmar que ambas técnicas son equivalentes y concluir que la técnica de recuento por la microgota es una alternativa adecuada para ser incluida dentro del mencionado protocolo consenso.

Abstract Quality evaluation of commercial inoculants is essential to warrant an adequate cropresponse to inoculation within a biosecurity framework. In this sense, this work is aimed at standardizing and validating the drop plate method for the enumeration of Azospirillum viable cellsas an alternative to the spread plate technique, which is currently proposed in the consensusprotocol of the REDCAI network. Between 14 and 25 private and public laboratories partici-pated in three independent trials. We obtained consistent and robust results that allowed toconfirm that both techniques are equivalent, concluding that the drop plate method is an alternative enumeration technique that is adequate to be included in the abovementioned consensusprotocol.

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11.

Recomendaciones de manejo de los anticoagulantes orales directos (DOACs) anti Xa y anti IIa
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Ceresetto, José M.

; Tajer, Carlos

; Duboscq, Cristina

; Bottaro, Federico

; Casais, Patricia

; Korin, Jorge

; Fondevila, Carlos

; Giumelli, Carla

; Scazziota, Alejandra

; Rossi, Andrea

; Botto, Fernando

; Ariscancela, Maria Ester

; Martinuzzo, Marta

; Zaidel, Ezequiel

; Fitz Maurice, Mario

; Bahit, Cecilia

; Vazquez, Fernando

; Molnar, Soledad

; Saizberg, Simón

; Negri Aranguren, Pedro

; Rosa, Claudio

; Fedele, José Luis

; Comignani, Pablo

; Pombo, Gonzalo

; Raña, Pablo

; Adamczuk, Yolanda

; Martí, Alejandra

; Charask, Adrián

; Penchasky, Diana

; Riveros, Dardo

; Mariani, Javier

; Puente, Dolores

; Celebrin, Lucia

; Bosio, Martín

; Brodsky, Andrés

; Sanchez Lucero, Analía

; Castillo Costa, Yanina

; Hirschson, Alfredo

; Arbesú, Guillermo

; Viñuales, Susana

; Kazelian, Lucía

; Maneyro, Alberto

; Gutierrez, Victoria

; Castro Rios, Miguel

; Gagliardi, Juan

; Lescano, Adrián

; Repetto, Fernanda

Medicina (Buenos Aires)

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apr 2022, Volume 82 Suppl. 2 Pages 1 - 55

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Direct oral anticoagulants have emerged as the drugs that have changed the man agement of the antithrombotic treatment in the last 15 years. Their advantages, like a more friendly way of anticoagulation and their lower risk of bleeding, especially in the brain, have positioned these new anticoagu lants as the first drug of choice in the two most frequent indications of anticoagulation, atrial fibrillation, and the venous thromboembolic disease. However, not all the patients can receive these agents, not all the direct oral anticoagulants have the same characteristics, and most importantly, not all the diseases with an indication of an anticoagulant drug can be treated with them. Therefore, it is mandatory that all the faculties involved in the management of these drugs must know them in depth, to decide the best treatment for the patient. This position paper, from a group of experts in anticoagulation in Argentina, can help the general practitioner in the daily use of direct oral anticoagulants based on the new evidence and the experience of a wide group of professionals. The way we relate to the anticoagulant treatment has changed in the last years. The doctors who work with them must also do so.

Resumen Los anticoagulantes orales directos han surgido como una de las herramientas que ha cambiado el manejo de la enfermedad trombótica en los últimos 15 años. Sus ventajas, desde el punto de vista de la facilidad de uso y menor riesgo de sangrado, especialmente de sangrado cerebral, han posicionado a estos nuevos anticoagulantes como la primera alternativa de tratamiento en las dos indicaciones más frecuentes en que necesitamos estas drogas, la fibrilación auricular y la enfermedad tromboembólica venosa. Sin embargo, no todos los pacientes pueden recibir estos agentes, no todos los anticoagulantes directos tienen las mismas pro piedades y fundamentalmente, no todas las enfermedades con indicación de un anticoagulante pueden tratarse con ellos;con lo cual es necesario que todos los profesionales que están involucrados en el manejo de estos medicamentos estén obligados a conocerlos en profundidad, para poder decidir el mejor tratamiento en cada caso particular. Este documento de posición de expertos de diferentes especialidades de Argentina, presenta lineamientos para el uso correcto de los anticoagulantes directos en base a nueva evidencia y a la experiencia de uso de un amplio grupo de profesionales. La forma de relacionarnos con el tratamiento anticoagulante ha cambiado. Los médicos que trabajamos con ellos también debemos hacerlo.

810 downloads

12.

Deficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis
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Lucchetta, Rosa Camila

; Lemos, Isabele Held

; Gini, Ana Luísa Rodriguez

; Cavicchioli, Sophia de Andrade

; Forgerini, Marcela

; Varallo, Fabiana Rossi

; Nadai, Mariane Nunes de

; Fernandez-Llimos, Fernando

; Mastroianni, Patricia de Carvalho

Revista Brasileira de Ginecologia e Obstetrícia

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apr 2022, Volume 44 N. 4 Pages 409 - 424

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Estimar a prevalência de níveis inadequados de vitamina D e seus fatores associados para mulheres em idade fértil no Brasil. Métodos Uma revisão sistemática foi realizada (última atualização em maio de 2020). As meta-análises foram realizadas usando o inverso da variância para o modelo fixo com cálculo de proporção sumarizada por transformação arco-seno duplo de Freeman-Tukey. A qualidade metodológica e de reporte foi avaliada usando a ferramenta do Joanna Briggs Institute para estudos de prevalência. Resultados Nossa revisão identificou 31 estudos, compreendendo 4.006 participantes. Todos os estudos apresentaram pelo menos uma limitação, principalmente devido ao uso de amostra de conveniência e tamanho amostral pequeno. As prevalências gerais de deficiência, insuficiência e deficiência de vitamina D foram 35% (intervalo de confiança, IC 95%: 34-37%), 42% (IC 95%: 41-44%) e 72% (IC 95%: 71-74%), respectivamente. Conclusão Embora a magnitude da prevalência de níveis inadequados de vitamina D seja incerta, a evidência sugere que presença de deficiência ou insuficiência de vitamina D em mulheres em idade reprodutiva pode causar problemas moderados a graves.

Abstract Objective To estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil. Methods A systematic reviewwas conducted (last updatedMay 2020).Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. Results Our review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively. Conclusion Although the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems.

https://doi.org/10.1055/s-0042-1742409

13.

The effects of pharmacist interventions on health outcomes in patients with advanced prostate cancer in Brazil
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Aguiar, Patricia M

; Mori, Ana Luiza PM

; Lima, Maria GF de

; Rossi, Magali SPN

; Nicoletti, Maria Aparecida

; Martins, Karina OF

; Lopes, Ana Lúcia M

; Coan, Teresa Cristina M

; Fugita, Oscar Eduardo H

; Storpirtis, Sílvia

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e19273

Abstract: En | Text: En | PDF: En

Abstract This study examined the effects of pharmacist interventions for patients with advanced prostate cancer. A pre-post study was conducted between October 2014 and August 2017 in a community pharmacy in Brazil for outpatients with advanced prostate cancer, aged ≥ 18 years, using cyproterone acetate and/or goserelin. The patients had face-to-face meetings with a pharmacist who dispensed antiandrogenic drugs and performed interventions aimed at solving and/or preventing drug-therapy problems. Primary outcomes regarding prostate-specific antigen (PSA) and testosterone levels were compared at 0, 6, and 12 months, whereas secondary outcomes-medication adherence and quality of life-were compared at baseline and at the 12-month follow-up. Medication adherence was assessed using the Morisky-Green test, and quality of life was measured by the Medical Outcomes Study 36-item Short Form (SF-36) and the Functional Assessment of Cancer Therapy-Prostate (FACT-P). The analysis included 20 patients; 311 drug-therapy problems were identified and most of them were related to adverse reactions (78.5%). The most common adverse reactions were reduced libido, erectile dysfunction, hyperglycemia, fatigue, and gynecomastia. Testosterone levels significantly decreased at 6 months, and PSA levels at 6 and 12 months. No significant changes in adherence were noted at the end of the study. A significant increase in the “pain” domain and an improvement trend in the “physical aspects” and “vitality” domains were observed based on the SF-36 instrument. The findings show that pharmacist interventions were able to improve PSA and testosterone levels, and some domains of quality of life of patients.

https://doi.org/10.1590/s2175-97902021000219273

14.

SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
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Pereira, Maria Fernanda Bádue

; Suguita, Priscila

; Litvinov, Nadia

; Farhat, Sylvia Costa Lima

; Paula, Camila Sanson Yoshino de

; Lázari, Carolina dos Santos

; Bedê, Pedro Vale

; Framil, Juliana Valeria de Souza

; Bueno, Catarina

; Branas, Priscila Cristina Abduch Adas

; Guimarães, Irina Monteiro da Costa

; Leite, Marcia Marques

; Navega, Ana Carolina Barsaglini

; Nanbu, Danilo Yamamoto

; Schvartsman, Claudio

; Pinho, João Renato Rebello

; Silva, Clovis Artur Almeida

; Marques, Heloisa Helena de Sousa

; Eisencraft, Adriana Pasmanik

; Rossi Jr, Alfio

; Delgado, Artur Figueiredo

; Leal, Gabriela Nunes

; Gibelli, Maria Augusta Cicaroni

; Palmeira, Patricia

; Sakita, Neusa Keico

; Santos, Emilly Henrique dos

; Rocha, Mussya Cisotto

; Kanunfre, Kelly Aparecida

; Okay, Thelma Suely

; Carneiro-Sampaio, Magda

; Carvalho, Werther Brunow de

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volume 64 elocation e34

Abstract: En | Text: En | PDF: En

ABSTRACT This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.

https://doi.org/10.1590/s1678-9946202264034

15.

Deficiency of vitamins C and E in women of childbearing age in Brazil: a systematic review and meta-analysis
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Lucchetta, Rosa Camila

; Cavicchioli, Sophia de Andrade

; Gini, Ana Luísa Rodriguez

; Forgerini, Marcela

; Varallo, Fabiana Rossi

; Nadai, Mariane Nunes de

; Fernandez-Llimos, Fernando

; Mastroianni, Patricia de Carvalho

Sao Paulo Medical Journal

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dec 2021, Volume 139 N. 6 Pages 545 - 555

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Despite the several options available for supplements containing vitamins C and E, evidence regarding the prevalence of deficiency or insufficiency of these vitamins is weak. OBJECTIVES: To estimate the prevalence of deficiency or insufficiency of vitamins C and E and associated factors among women of childbearing age, in Brazil. DESIGN AND SETTING: Systematic review and meta-analysis conducted at a Brazilian public university. METHODS: A search from index inception until May 2020 was conducted. Meta-analyses were performed using inverse variance for fixed models, with summary proportions calculation using Freeman-Tukey double arcsine (base case). Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. RESULTS: Our review identified 12 studies, comprising 1,316 participants, especially breastfeeding women. There was at least one quality weakness in all studies, mainly regarding sampling method (i.e. convenience sampling) and small sample size. The prevalence of vitamin C deficiency ranged from 0% to 40%. Only vitamin E deficiency was synthetized in meta-analyses, with mean prevalences of 6% regardless of the alpha-tocopherol cutoff in plasma, and 5% and 16% for cutoffs of < 1.6-12.0 mmol/l and < 16.2 mmol/l, respectively. The cumulative meta-analysis suggested that a trend to lower prevalence of vitamin E deficiency occurred in recent studies. CONCLUSIONS: Although the studies identified in this systematic review had poor methodological and reporting quality, mild-moderate vitamin C and E deficiencies were identified, especially in breastfeeding women. Thus, designing and implementing policies does not seem to be a priority, because the need has not been properly dimensioned among women of childbearing age in Brazil. REGISTRATION NUMBER IN PROSPERO: CRD42020221605.

https://doi.org/10.1590/1516-3180.2020.0799.r1.0904221

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