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ABSTRACT The effects of diets containing oilseeds were measured to evaluate the productive and economic parameters in the finishing of young, feedlot Nellore bulls. Twenty-four young Nellore bulls were used, with an initial body weight (BW) of 311.46±0.37 kg and 24 months of age, distributed into individual stalls ( 4 × 20 m) in a completely randomized design, totaling four treatments with six repetitions per treatment. Four diets (control, based on corn and soybean meal, and three diets containing cottonseed, soybean, and sunflower) were evaluated. Feed and orts were measured daily to calculate intake and costs. The dry matter intake of the control group was higher than soybean (10.64 kg/day), cotton (9.88 kg/day), and sunflower (9.30 kg/day) treatments, respectively. The cottonseed treatment showed the highest average neutral detergent fiber intake. There was a dietary effect of diets on average daily gain, total weight gain, and final weight. The soybean treatment showed the highest performance, total gain (232.55 kg), and final weight (544.38 kg). Oilseed intake can modify the fatty acids profile in the meat, decreasing its saturated fatty acid content. Whole soybean seed favors performance, improves feed efficiency, fatty acid profile, and fat distribution in the carcass, and can reduce production costs.

https://doi.org/10.37496/rbz5220220160

Paleoenvironment of the Cerro Negro Formation (Aptian, Early Cretaceous) of Snow Island, Antarctic Peninsula
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SANTOS, ALESSANDRA

; PIOVESAN, ENELISE KATIA

; GUZMÁN, JULIANA

; USMA, CRISTIAN D.

; WEINSCHÜTZ, LUIZ CARLOS

; SANTOS, RADARANY JASMINE M. DOS

; OLIVEIRA, GUSTAVO R.

; FIGUEIREDO, RODRIGO G.

; RICETTI, JOÃO HENRIQUE Z.

; WILNER, EVERTON

; SAYÃO, JULIANA M.

; KELLNER, ALEXANDER W.A.

Anais da Academia Brasileira de Ciências

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2022, Volume 94 Suppl. 1 elocation e20201944

Abstract: En | Text: En | PDF: En

Abstract A study of macro and microfacies, palynoflora and palynofacies of the non-marine Cerro Negro Formation at President Head Peninsula, Snow Island, northwest of the Antarctic Peninsula, was developed. Two assemblages were recognized: Palynofacies assemblage 1 (P1) at the base of the section with a dominance of fern spores and conifer pollen grains, and facies association consisting of a clastic layer, with the predominance of mudstones; and Palynofacies assemblage 2 (P2) at the top of the section, with remarkable abundance of AOM/Pseudoamorphous particles, associated with facies that includes tuffs. The complete section shows in some levels the presence of freshwater algae and translucent phytoclasts. The integrated data characterizes a fluvial-lacustrine environment, what is reinforced by the occurrence of freshwater algae (Botryococcus) in some levels of P1 and P2. We could verify an increase in volcanic activity towards the top of the section that apparently has played an important role in the collapse of the palynoflora. The occurrence of the spore species Muricingulisporis annulatus, Sotasporites elegans, S. triangularis, Foraminisporis wonthaggiensis, and F. asymmetricus in the Cerro Negro Formation allows the correlation with sections in South America and Australia, suggesting an Aptian age for these deposits.

https://doi.org/10.1590/0001-3765202220201944

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

Benthic macrofauna associated to the invasive bivalve Mytilopsis leucophaeata (Dreissenidae) in a coastal lagoon in Rio de Janeiro, Brazil
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RODRIGUES, ANTONIO JAILSON DE S.

; FERNANDES, MAURÍCIO R.

; MIYAHIRA, IGOR C.

; SANTOS, LUCIANO N. DOS

; CAETANO, CARLOS HENRIQUE S.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 N. 4 elocation e20191221

Abstract: En | Text: En | PDF: En

Abstract The invasion record for the estuarine bivalve Mytilopsis leucophaeata in Brazil is in Rio de Janeiro city, including the Rodrigo de Freitas Lagoon, where high densities of this invader were registered. This work aimed to (1) assess the composition and structure of the benthic macrofauna associated with this invader in Rodrigo de Freitas Lagoon, (2) analyze the spatiotemporal variation of richness, density and diversity of the associated benthic community, and (3) correlate changes on the density of the associated benthic species with some water quality variables and the density of M. leucophaeata. Clusters of M. leucophaeata were collected monthly (two years) in four sites. Nine taxa associated with M. leucophaeata were found; Heleobia sp. (Gastropoda) and Melita mangrovi (Amphipoda) showed the highest densities. The structure of the benthic macrofauna slightly differed among sampling sites, but not between dry and wet seasons. The water quality parameters, specific patterns of each taxon and high densities of M. leucophaeata contribute to variations in density of the associated species. Oscillations in the densities of M. leucophaeata and the native bivalve Brachidontes darwinianus suggest some agonistic relationship between them, such as a competition for space.

https://doi.org/10.1590/0001-3765202120191221 78 downloads

Diagnostic prediction model for levodopa-induced dyskinesia in Parkinson’s disease
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SANTOS-LOBATO, Bruno Lopes

; SCHUMACHER-SCHUH, Artur F.

; RIEDER, Carlos R. M.

; HUTZ, Mara H.

; BORGES, Vanderci

; FERRAZ, Henrique Ballalai

; MATA, Ignacio F.

; ZABETIAN, Cyrus P.

; TUMAS, Vitor

Arquivos de Neuro-Psiquiatria

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apr 2020, Volume 78 N. 4 Pages 206 - 216

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: No momento, não há métodos para se predizer o desenvolvimento de discinesias induzidas por levodopa (DIL), uma frequente complicação do tratamento da doença de Parkinson (DP). Preditores clínicos e polimorfismos de nucleotídeo único (SNP) têm sido associados às DIL na DP. Objetivo: Investigar a associação entre variáveis clínicas e genéticas com as DIL e desenvolver um modelo de predição diagnóstica de DIL na DP. Métodos: Foram avaliados 430 pacientes com DP em uso de levodopa. A presença de DIL foi definida como escore ≥1 no item 4.1 da MDS-UPDRS Parte IV. Nós testamos a associação entre variáveis clínicas específicas e sete SNPs com o desenvolvimento de DIL, usando modelos de regressão logística. Resultados: Em relação às variáveis clínicas, idade de início da doença, duração da doença, sintomas motores iniciais e uso de agonistas dopaminérgicos estiveram associados às DIL. Apenas o genótipo CC do SNP rs2298383 no gene ADORA2A esteve associado com DIL após o ajuste. Nós desenvolvemos dois modelos preditivos diagnósticos com acurácia razoável, mas sugerimos o uso do modelo preditivo clínico. Esse modelo de predição tem uma área sob a curva de 0,817 (intervalo de confiança de 95% [IC95%] 0,77‒0,85) e sem perda significativa de ajuste (teste de qualidade de ajuste de Hosmer-Lemeshow p=0,61). Conclusão: A probabilidade prevista de DIL pode ser estimada, com acurácia razoável, por meio do uso de um modelo preditivo diagnóstico clínico, que combina a idade de início da doença, duração da doença, sintomas motores iniciais e uso de agonistas dopaminérgicos.

Abstract Background: There are currently no methods to predict the development of levodopa-induced dyskinesia (LID), a frequent complication of Parkinson's disease (PD) treatment. Clinical predictors and single nucleotide polymorphisms (SNP) have been associated to LID in PD. Objective: To investigate the association of clinical and genetic variables with LID and to develop a diagnostic prediction model for LID in PD. Methods: We studied 430 PD patients using levodopa. The presence of LID was defined as an MDS-UPDRS Part IV score ≥1 on item 4.1. We tested the association between specific clinical variables and seven SNPs and the development of LID, using logistic regression models. Results: Regarding clinical variables, age of PD onset, disease duration, initial motor symptom and use of dopaminergic agonists were associated to LID. Only CC genotype of ADORA2A rs2298383 SNP was associated to LID after adjustment. We developed two diagnostic prediction models with reasonable accuracy, but we suggest that the clinical prediction model be used. This prediction model has an area under the curve of 0.817 (95% confidence interval [95%CI] 0.77‒0.85) and no significant lack of fit (Hosmer-Lemeshow goodness-of-fit test p=0.61). Conclusion: Predicted probability of LID can be estimated with reasonable accuracy using a diagnostic clinical prediction model which combines age of PD onset, disease duration, initial motor symptom and use of dopaminergic agonists.

https://doi.org/10.1590/0004-282x20190191 1179 downloads

1º Posicionamento Brasileiro sobre o Impacto dos Distúrbios de Sono nas Doenças Cardiovasculares da Sociedade Brasileira de Cardiologia
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Drager, Luciano F.

; Lorenzi-Filho, Geraldo

; Cintra, Fatima Dumas

; Pedrosa, Rodrigo P.

; Bittencourt, Lia R. A.

; Poyares, Dalva

; Carvalho, Carolina Gonzaga

; Moura, Sonia Maria Guimarães Pereira Togeiro

; Santos-Silva, Rogerio

; Bruin, Pedro F. C. de

; Geovanini, Glaucylara R.

; Albuquerque, Felipe N.

; Oliveira, Wercules Antonio Alves de

; Moreira, Gustavo A.

; Ueno, Linda Massako

; Nerbass, Flávia Baggio

; Rondon, Maria Urbana Pinto Brandão

; Barbosa, Eline Rozária Ferreira

; Bertolami, Adriana

; Paola, Angelo Amato Vincenzo de

; Marques, Betânia Braga Silva

; Rizzi, Camila Futado

; Negrão, Carlos Eduardo

; Uchôa, Carlos Henrique Gomes

; Maki-Nunes, Cristiane

; Martinez, Denis

; Fernández, Edmundo Arteaga

; Maroja, Fabrizio U.

; Almeida, Fernanda R.

; Trombetta, Ivani C.

; Storti, Luciana J.

; Bortolotto, Luiz Aparecido

; Mello, Marco Túlio de

; Borges, Melania Aparecida

; Andersen, Monica Levy

; Portilho, Natanael de Paula

; Macedo, Paula

; Alves, Rosana

; Tufik, Sergio

; Fagondes, Simone C.

; Risso, Thaís Telles

Arquivos Brasileiros de Cardiologia

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aug 2018, Volume 111 N. 2 Pages 290 - 340

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.5935/abc.20180154 8719 downloads

Experience with pegvisomant treatment in acromegaly in a single Brazilian tertiary reference center: efficacy, safety and predictors of response
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Kasuki, Leandro

; Machado, Evelyn de Oliveira

; Ogino, Liana Lumi

; Coelho, Maria Caroline Alves

; Silva, Cintia Marques dos Santos

; Wildemberg, Luiz Eduardo Armondi

; Lima, Carlos Henrique Azeredo

; Gadelha, Mônica R.

Archives of Endocrinology and Metabolism

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oct 2016, Volume 60 N. 5 Pages 479 - 485

Abstract: En | Text: En | PDF: En

ABSTRACT Objective To describe the safety and efficacy of pegvisomant therapy and the predictors of treatment response in acromegaly patients at a single tertiary reference center in Brazil. Materials and methods We retrospectively reviewed the clinical, hormonal and radiological data of acromegaly patients treated with pegvisomant in our center. We also evaluated the presence of the d3 isoform of the growth hormone receptor (d3GHR). Results Twenty-seven patients were included (17 women). Pegvisomant was used in combination with octreotide LAR in 20 patients (74%), in combination with cabergoline in one (4%) and as monotherapy in six (22%). IGF-I normalization was achieved in 23 patients (85%). Mild and transitory elevation of liver enzymes was observed in two patients (7.4%), tumor growth in one (3.4%) and lipodystrophy in two (7.4%). One patient stopped the drug due to headaches. The GHR isoforms were evaluated in 14 patients, and the presence of at least one d3GHR allele was observed in 43% of them, but it was not a predictor of treatment response. Only pre-treatment IGF-I level was a predictor of treatment response. Conclusion Pegvisomant treatment was highly effective and safe in our series of Brazilian patients. A better chance of disease control can be expected in those with lower pre-pegvisomant IGF-I levels.

https://doi.org/10.1590/2359-3997000000210 1231 downloads

Estudo randomizado e controlado de uma intervenção terapêutica grupal em pacientes com síndrome fibromiálgica
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Martins, Marielza R. Ismael

; Gritti, Cristiane Carnaval

; Santos Junior, Randolfo dos

; Araújo, Maria Carolina Luizetto de

; Dias, Lilian Chessa

; Foss, Marcos Henrique D'all Aglio

; Andrade, Larissa Batista de

; Rocha, Carlos Eduardo D'all Aglio

Revista Brasileira de Reumatologia

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jun 2014, Volume 54 N. 3 Pages 179 - 184

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: Avaliar a eficácia de um programa interdisciplinar semanal (PIS) composto de atividades educativas, terapias físicas, alongamento, ergonomia, orientações posturais combinado com estratégias cognitivas e comportamentais e abordagens de aspectos psicossociais e ocupacionais, a fim de determinar se esta intervenção seria efetiva em curto e médio prazos para melhora dos sintomas destes pacientes. Casuística e métodos: Trata-se de um estudo unicêntrico, randomizado, simples cego e controlado com amostra de um grupo-teste (T), com diagnóstico de SFM (n = 12), e de um grupo-controle (C) submetido a interconsulta na Clínica da Dor (n = 15). Os instrumentos utilizados em dois momentos distintos foram: Questionário de Impacto de Fibromialgia (FIQ), Escala Visual Analógica (EVA) e Protocolo Pós-Sono (PSI). Para avaliar a qualidade de vida, foi utilizado o Questionário SF-12. Resultados: Na amostra dos dois grupos houve predomínio do gênero feminino, média de idade de 42,5±9,8 anos, 43% casados e média de escolaridade de 8,3±4,5 anos. Foi relatado um tempo médio de dor de 4,2 anos e uma média de dois anos para o diagnóstico de SFM no grupo T. Houve diferença estatística entre os grupos, em relação à eficácia pós-intervenção do PIS, em quase todos os desfechos analisados. Conclusão: Verificou-se que o programa interdisciplinar semanal (PIS) contribuiu para melhora da qualidade de vida dos pacientes fibromiálgicos.

https://doi.org/10.1016/j.rbr.2013.10.005 6418 downloads

10.

Emetofobia: revisão crítica sobre um transtorno pouco estudado
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Leite, Carlos Eduardo Paula

; Vicentini, Henrique Cláudio

; Neves, Joyce dos Santos

; Torres, Albina R.

Jornal Brasileiro de Psiquiatria

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2011, Volume 60 N. 2 Pages 123 - 130

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: A emetofobia ou fobia de vômitos - que inclui o medo excessivo de vomitar ou de ver outras pessoas vomitando e pode ser desencadeado por estímulos internos e externos - é um transtorno mental complexo e pouco conhecido. OBJETIVO: Este estudo teve como objetivo levantar os conhecimentos disponíveis sobre diversos aspectos do quadro. MÉTODO: Revisão convencional da literatura dos últimos 30 anos utilizando como estratégia de busca as seguintes palavras-chave: "emetofobia", "emetofóbico", "medo de vomitar", "fobia de vomitar" e"fobia de vômito". Foram incluídos artigos sobre epidemiologia, fenomenologia, diagnóstico diferencial e tratamento da emetofobia, assim como artigos referidos nestes. RESULTADOS: Não há dados de prevalência na população geral e pouco se sabe sobre a etiologia da emetofobia. A maioria dos estudos aponta predominância no sexo feminino, início precoce e curso crônico. Os comportamentos de esquiva podem impactar negativamente a vida ocupacional, social e familiar. Os principais diagnósticos diferenciais são: transtorno de pânico com agorafobia, fobia social, anorexia nervosa e transtorno obsessivo-compulsivo. Estudos de tratamento se resumem a relatos de casos e não há ensaios clínicos controlados, mas intervenções cognitivo-comportamentais parecem ser promissoras. CONCLUSÃO: Mais estudos são necessários para melhor compreensão sobre a epidemiologia, o quadro clínico, a etiologia, a classificação e o tratamento da emetofobia.

INTRODUCTION: Emetophobia or fear of vomit - which includes an excessive fear of vomiting or seeing other people vomiting and can be triggered by internal and external stimuli -is a complex and fairly unknown disorder. OBJECTIVE: This study aimed at reviewing the current knowledge about this condition. METHOD: A conventional literature review of the previous 30 years, using as search strategy the following keywords: "emetophobia", "emetophobic", "fear of vomiting", "vomiting phobia", and "phobia of vomit". All articles about the epidemiology, phenomenology, differential diagnosis and treatment of emetophobia were included, as well as articles cited in these ones. RESULTS: There are no available data on the prevalence in the general population and little is known about the etiology of emetophobia. Most studies describe predominance in females, early onset and chronic course. The avoidant behaviors can have a significant impact on occupational, social and family lives. The most important differential diagnoses are: panic disorder with agoraphobia, social phobia, anorexia nervosa and obsessive-compulsive disorder. Treatment studies are mostly case reports and no controlled clinical trials have been published. Cognitive-behavioral interventions, however, seem to be promising. CONCLUSION: More studies are needed for a better understanding of the epidemiology, clinical picture, etiology, classification and treatment of emetophobia.

35969 downloads

11.

Anti-hypertensive drugs have different effects on ventricular hypertrophy regression
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Ferreira Filho, Celso

; Abreu, Luiz Carlos de

; Valenti, Vitor E.

; Ferreira, Marcelo

; Meneghini, Adriano

; Silveira, José Alexandre

; Riera, Andrés R. Pérez

; Colombari, Eduardo

; Murad, Neif

; Santos-Silva, Paulo Roberto

; Silva, Lovian José Henrique Pereira da

; Vanderlei, Luiz Carlos Marques

; Carvalho, Tatiana D.

; Ferreira, Celso

Clinics

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2010, Volume 65 N. 7 Pages 723 - 728

Abstract: En | Text: En | PDF: En

OBJECTIVES: There is a direct relationship between the regression of left ventricular hypertrophy (LVH) and a decreased risk of mortality. This investigation aimed to describe the effects of anti-hypertensive drugs on cardiac hypertrophy through a meta-analysis of the literature. METHODS: The Medline (via PubMed), Lilacs and Scielo databases were searched using the subject keywords cardiac hypertrophy, antihypertensive and mortality. We aimed to analyze the effect of anti-hypertensive drugs on ventricle hypertrophy. RESULTS: The main drugs we described were enalapril, verapamil, nifedipine, indapamina, losartan, angiotensin-converting enzyme inhibitors and atenolol. These drugs are usually used in follow up programs, however, the studies we investigated used different protocols. Enalapril (angiotensin-converting enzyme inhibitor) and verapamil (Ca++ channel blocker) caused hypertrophy to regress in LVH rats. The effects of enalapril and nifedipine (Ca++ channel blocker) were similar. Indapamina (diuretic) had a stronger effect than enalapril, and losartan (angiotensin II receptor type 1 (AT1) receptor antagonist) produced better results than atenolol (selective β1 receptor antagonist) with respect to LVH regression. CONCLUSION: The anti-hypertensive drugs induced various degrees of hypertrophic regression.

4075 downloads

12.

A comparative study of irradiation systems for photoinactivation of microorganisms
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Paula, Lucas F. de

; Santos, Renata O.

; Menezes, Henrique D.

; Britto, Jonas R. de

; Vieira Jr, João B.

; Gontijo Filho, Paulo P.

; Oliveira, Carlos A. de

Journal of the Brazilian Chemical Society

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2010, Volume 21 N. 4 Pages 694 - 700

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Estudou-se a construção de sistemas de LED aplicados a processos de fotosensitização. Visando à obtenção de dispositivos mais eficientes avaliou-se a aplicação de LED de alta potência (HPLED), que apresenta maior fluxo fotônico, tendendo a excitar uma maior fração de moléculas. Foram descritos detalhes de construção de 3 diferentes sistemas de irradiação completamente distintos (lâmpada halógena filtrada, LED convencional, HPLED), utilizando azul de metileno como fotosensitizador. A comparação entre a eficiência de cada equipamento foi realizada através da cinética de fotooxidação de 1,3-Diphenylisobenzofuran e inativação de Staphylococcus aureus. A emissão de luz de cada equipamento, sobreposta à absorção do fotosensitizador, também se mostrou um importante parâmetro na estimativa da eficiência dos equipamentos. Foi observada uma inibição bacteriana superior a 99% para concentrações de 5 × 10-6 mol dm-3 de fotosensitizador, no sistema que emprega HPLED. Os equipamentos baseados em LED, apresentaram resultados satisfatórios além de baixo custo e simples montagem.

The construction of LED systems applied to photosensitization processes was studied. Aiming to obtain more efficient devices it was evaluated the use of high intensity LED (HPLED), that present greater photonic flux, tending to excite a greater fraction of molecules. Construction details for 3 different irradiation systems were described (filtered halogen bulbs, conventional LED, HPLED), using methylene blue as a photosensitizer. A comparison between the efficiency of the equipments was carried out through the kinetics of photooxidation of 1,3-Diphenylisobenzofuran and Staphylococcus aureus photoinactivation. The overlap between the light emited from each equipment and the photosensitizer absorption, was also an important parameter in estimating the efficiency of the equipment. Bacterial inhibition higher than 99% for concentrations of 5 × 10-6 mol dm-3 of the photosensitizer was observed, in the system that uses HPLED. The equipments based on LED showed satisfactory results, besides their low cost and simple to assembling.

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13.

Ontologias como novas bases de conhecimento científico
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Marcondes, Carlos Henrique

; Mendonça, Marília Alvarenga R.

; Malheiros, Luciana Reis

; Costa, Leonardo Cruz da

; Santos, Tatiana Cristina Paredes dos

Perspectivas em Ciência da Informação

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dec 2008, Volume 13 N. 3 Pages 20 - 39

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Periódicos científicos publicadosna Web são ainda calcados no modelo impresso. O conhecimento aí contido está em forma textual, não processável por programas. É proposto um modelo de ambiente de publicação na Web que permita a autores publicar seu artigo simultaneamente em formato textual e em formato "inteligível" por programas. Como domínio para avaliação e aperfeiçoamento do modelo, foram analisados 60 artigos de periódicos eletrônicos em Ciências da Saúde. O modelo e os resultados da análise são expostos e discutidos.

Scientific journals published on the Web are still based on a print model. Knowledge in those articles is in text format which is not processable by softwares. A Web publishing environment is proposed which enables authors to publish articles both as a text and a software "understandable" format. Sixty articles from Health Science electronic journals were analyzed to test and evaluate the model. The results of the analysis and the model proposed are shown and discussed.

7987 downloads Cited 2 times in SciELO

14.

Transtorno bipolar do humor e gênero
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Dias, Rodrigo da Silva

; Kerr-Corrêa, Florence

; Torresan, Ricardo Cezar

; Santos, Carlos Henrique R. dos

Archives of Clinical Psychiatry (São Paulo)

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2006, Volume 33 N. 2 Pages 80 - 91

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Embora o transtorno bipolar (TB) ocorra quase igualmente em ambos os sexos, a fenomenologia e o curso da doença diferem no homem e na mulher. No entanto, há evidências de que mulheres bipolares, mais que os homens, apresentariam início mais tardio (em especial na quinta década de vida), ciclagem rápida, mais episódios depressivos, mais mania disfórica que eufórica, estados mistos e evolução do tipo bipolar II, ainda que os achados nem sempre sejam consistentes. Embora o risco de comorbidades no TB inclua, para ambos os gêneros, abuso de álcool e drogas, homens bipolares teriam maior probabilidade de ser alcoolistas, não procurar tratamento e de se suicidar. Hipóteses sugeridas para explicar tais diferenças variam daquelas centradas em aspectos culturais ou psicológicos para as que focalizam os sistemas hormonais, como os esteróides gonadais ou o eixo tireoidiano, e até mesmo a anatomia cerebral. A influência do ciclo reprodutivo (ciclo menstrual, gravidez e menopausa) sobre as opções terapêuticas no tratamento do TB é apresentada na última parte desta revisão.

Although the bipolar disorder (BD) occurs almost with the same frequency in both genders, the phenomenology and the outcome of the illness differ between them. Nevertheless, there is evidence that women with BD show, more than men, delayed beginning, especially in their fifth decade, more rapid cycling outcome, more depressive episodes, more dysphoric mania, more mixed states and more BD type II. Even so, the findings are not always consistent. Although the risk of comorbidities in BD includes, for both the sorts, excessive alcoholic consumption and drugs, bipolar men would have greater probability of being alcohol dependent, of not seeking treatment and of committing suicide. Suggested hypotheses to explain such differences vary from those centered in cultural or psychological aspects to those that focus on the steroids hormones, and other hormones such as cortisol, thyroid hormones and even on the cerebral anatomy. The reproductive cycle (menstrual cycle, pregnancy and menopause) influences on the BD phenomenology and its relevance to the therapeutical options in the treatment of the BD in women are presented in the last part of this review. Further investigations must to be done in order to clarify this controversy. However, up to now the data indicate that estrogen therapy is not to be primarily indicated to prevent depression, Alzheimer disease or cognition impairment.

15865 downloads Cited 5 times in SciELO

15.

Variability of the anthracnose fungus Colletotrichum graminicola in sorghum genotype mixtures
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Valério, Henrique M.

; Casela, Carlos R.

; Resende, Maria A.

; Santos, Fredolino G.

Fitopatologia Brasileira

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oct 2004, Volume 29 N. 5 Pages 567 - 569

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O presente trabalho relata resultados parciais sobre a variabilidade de Colletotrichum graminicola, agente causal da antracnose do sorgo (Sorghum bicolor), desenvolvida em resposta à diversidade gerada na população hospedeira através de misturas formadas pela combinação, três a três, de diferentes linhagens de sorgo. Nove linhagens foram utilizadas neste estudo: CMSXS210B, CMSXS112B, CMSXS215B, CMSXS221B, CMSXS169R, CMSXS180R, CMSXS182R, CMSXS227R, and CMSXS116R. Misturas e estandes puros de cada linhagem componente, em um total de 39 tratamentos, foram avaliados no campo, para o desenvolvimento da antracnose em condições de infecção natural. Amostras de isolados monospóricos do patógeno obtidas de cada tratamento indicaram uma redução na diversidade fenotípica do patógeno e um aumento na freqüência de raças de maior complexidade em todas as misturas em relação aos estandes puros de cada genótipo.

This paper reports partial results obtained on the variability of Colletotrichum graminicola developed in response to the host diversity generated by three-line combination of sorghum (Sorghum bicolor) genotypes. Nine sorghum lines were used in this study: CMSXS210B, CMSXS112B, CMSXS215B, CMSXS221B, CMSXS169R, CMSXS180R, CMSXS182R, CMSXS227R, and CMSXS116R. A total of 39 treatments on mixtures and pure stands of the component lines were evaluated in the field for the development of anthracnose, as a natural epidemic. Samples of the single spore isolates of the pathogen of each treatment indicated a reduction in the phenotypic diversity and an increase in the frequency of more complex races in genotype mixtures in relation to the pure stands of each genotype.

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