Search | SciELO

ABSTRACT Objective: To evaluate autoinflammatory diseases (AID) according to age at diagnosis and sex, and response to therapy in a large population. Methods: This is a cross-sectional observational study of a Latin American registry using a designed web system for data storage, collected between 2015 and 2018. Any altered findings during follow-up were recorded. The forms were translated into Portuguese and Spanish, including demographic, clinical, laboratory, genetic and treatment characteristics. Results: We included 152 patients, 51.3% male and 75% Caucasian. The median age at disease onset was 2.1 years (0–15.6 years) and median age at diagnosis 6.9 years (0–21.9 years); 111 (73%) were children (0–9 years old), and 41 (27%) were adolescents and young adults (AYA) (10–21 years old). Periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome (PFAPA) occurred in 46/152 (30%), chronic non-bacterial osteomyelitis (CNO) in 32/152 (21%), and familial Mediterranean fever (FMF) in 24/152 (15.7%). PFAPA was significantly higher in young children than in AYA (38.7% vs. 7.3%, p<0.001), while CNO were lower (13.5% vs. 41.5%, p<0.001). The frequency of females was significantly higher in CNO (28.4% vs. 14.1%, p=0.031) and lower in FMF (8.1% vs. 23.1%, p=0.011). The most used drugs were glucocorticoids, non-steroidal anti-inflammatory drugs (NSAID), and colchicine. Glucocorticoids and colchicine treatment were used in all AID with good to moderate response. However, cryopyrin-associated periodic syndromes (CAPS) seemed unresponsive to glucocorticoids. NSAIDs and methotrexate were the main medications used to treat CNO. Conclusions: Differences among AID patients were observed in the LA population regarding sex and age at disease diagnosis.

RESUMO Objetivo: Avaliar as doenças autoinflamatórias (DAI) de acordo com sexo e idade no momento do diagnóstico e a resposta terapêutica em uma grande população. Métodos: Este é um estudo observacional transversal de um registro latino-americano que usou um sistema de dados coletados entre 2015 e 2018. Quaisquer achados alterados ao longo do acompanhamento foram registrados. Os formulários foram traduzidos para os idiomas português e espanhol, incluindo características demográficas, clínicas, laboratoriais, genéticas e de tratamento. Resultados: Incluímos 152 pacientes, sendo 51,3% do sexo masculino e 75% da raça branca. A média de idade de início da doença foi de 2,1 anos (0–15,6 anos) e a média de idade de diagnóstico 6,9 anos (0–21,9 anos); 111 (73%) eram crianças (0–9 anos) e 41 (27%) adolescentes/adultos jovens (10–21 anos). A síndrome de febre periódica, estomatite aftosa, faringite e adenite (PFAPA) ocorreu em 46/152 (30%), osteomielite não bacteriana crônica (CNO) em 32/152 (21%) e febre familiar do Mediterrâneo (FMF) em 24/152 (15,7%). A PFAPA foi significativamente maior em crianças pequenas (38,7 vs. 7,3%, p<0,001), e a CNO, em adolescentes/adultos jovens (13,5 vs. 41,5%, p<0,001). A frequência do sexo feminino foi significativamente maior na CNO (28,4 vs. 14,1%, p=0,031) e menor na FMF (8,1 vs. 23,1%, p=0,011). Os medicamentos mais utilizados foram glicocorticoides, anti-inflamatórios não esteroidais (AINE) e colchicina. O tratamento com glicocorticoides e colchicina foi usado em todas as DAI com resposta boa a moderada. No entanto, as síndromes periódicas associadas à criopirina (CAPS) pareciam não responder aos glicocorticoides. AINE e metotrexato foram os principais medicamentos utilizados no tratamento da CNO. Conclusões: Diferenças de pacientes com DAI foram observadas na população latino-americana em pacientes agrupados por sexo e idade ao diagnóstico da doença.

https://doi.org/10.1590/1984-0462/2024/42/2022184

Risk factors for the development of surgical site infection in bariatric surgery: an integrative review of literature
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Ana Flávia da

; Mendes, Karina Dal Sasso

; Ribeiro, Vanessa dos Santos

; Galvão, Cristina Maria

Revista Latino-Americana de Enfermagem

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2023, Volume 31 elocation e3798

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective: to evaluate evidence on risk factors for the development of surgical site infection in bariatric surgery. Method: integrative review. The search for primary studies was performed in four databases. The sample consisted of 11 surveys. The methodological quality of the included studies was assessed using tools proposed by the Joanna Briggs Institute. Data analysis and synthesis were performed in a descriptive manner. Results: surgical site infection rates ranged from 0.4% to 7.6%, considering the results of primary studies, in which patients underwent laparoscopic surgery. In surveys of participants undergoing surgical procedures with different approaches (open, laparoscopic or robotic), infection rates ranged from 0.9% to 12%. Regarding the risk factors for the development of this type of infection, antibiotic prophylaxis, female sex, high Body Mass Index and perioperative hyperglycemia are highlighted. Conclusion: conducting the integrative review generated a body of evidence that reinforces the importance of implementing effective measures for the prevention and control of surgical site infection, by health professionals, after bariatric surgery, promoting improved care and patient safety in the perioperative period.

Resumen Objetivo: evaluar las evidencias sobre los factores de riesgo para el desarrollo de infección de sitio quirúrgico en cirugía bariátrica. Método: revisión integradora. La búsqueda de estudios primarios se realizó en cuatro bases de datos. La muestra estuvo compuesta por 11 investigaciones. La calidad metodológica de los estudios incluidos se evaluó mediante herramientas propuestas por el Joanna Briggs Institute. El análisis y la síntesis de los datos se realizaron de manera descriptiva. Resultados: las tasas de infección del sitio quirúrgico oscilaron entre 0,4% y 7,6%, considerando los resultados de los estudios primarios, en los que los pacientes fueron sometidos a cirugía mediante laparoscopia. En investigaciones con participantes que se sometieron a procedimientos quirúrgicos con diferentes enfoques (abierto, laparoscópico o robótico), las tasas de infección oscilaron entre el 0,9 % y el 12 %. En cuanto a los factores de riesgo para el desarrollo de este tipo de infección, se destacan la profilaxis antibiótica, el sexo femenino, el Índice de Masa Corporal elevado y la hiperglucemia perioperatoria. Conclusión: la realización de la revisión generó un cuerpo de evidencia que refuerza la importancia de implementar medidas efectivas para la prevención y el control de la infección de sitio quirúrgico, por parte de los profesionales de la salud, después de la cirugía bariátrica, promoviendo la mejora de la atención y la seguridad del paciente en el período perioperatorio.

Resumo Objetivo: avaliar as evidências sobre os fatores de risco para o desenvolvimento de infecção de sítio cirúrgico em cirurgia bariátrica. Método: revisão integrativa. A busca dos estudos primários foi realizada em quatro bases de dados. A amostra foi composta por 11 pesquisas. A qualidade metodológica dos estudos incluídos foi avaliada por meio de ferramentas propostas pelo Joanna Briggs Institute. A análise e a síntese dos dados foram realizadas de maneira descritiva. Resultados: as taxas de infecção de sítio cirúrgico variaram de 0,4% até 7,6%, considerando os resultados dos estudos primários, cujos pacientes foram submetidos à cirurgia por via laparoscópica. Nas pesquisas com os participantes submetidos aos procedimentos cirúrgicos com diferentes abordagens (aberta, via laparoscópica ou robótica), as taxas de infecção variaram de 0,9% até 12%. Com relação aos fatores de risco para o desenvolvimento deste tipo de infecção, ressaltam-se antibioticoprofilaxia, sexo feminino, Índice de Massa Corporal elevado e hiperglicemia perioperatória. Conclusão: a condução da revisão gerou corpo de evidências que reforça a importância na implementação de medidas efetivas para prevenção e controle de infecção de sítio cirúrgico pelos profissionais de saúde após cirurgia bariátrica, promovendo a melhoria da assistência e da segurança do paciente no perioperatório.

https://doi.org/10.1590/1518-8345.6309.3798

The II Brazilian Guidelines for the pharmacological treatment of patients hospitalized with COVID-19 Joint Guidelines of the Associação Brasileira de Medicina de Emergência, Associação de Medicina Intensiva Brasileira, Associação Médica Brasileira, Sociedade Brasileira de Angiologia e Cirurgia Vascular, Sociedade Brasileira de Infectologia, Sociedade Brasileira de Pneumologia e Tisiologia and Sociedade Brasileira de Reumatologia
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Falavigna, Maicon

; Araujo, Cintia Laura Pereira de

; Barbosa, Alexandre Naime

; Belli, Karlyse Claudino

; Colpani, Verônica

; Dal-Pizzol, Felipe

; Silva, Rosemeri Maurici da

; Azevedo, Luciano César Pontes de

; Dias, Maria Beatriz Souza

; Amaral, José Luiz Gomes do

; Dorneles, Gilson Pires

; Ferreira, Juliana Carvalho

; Freitas, Ana Paula da Rocha

; Gräf, Débora Dalmas

; Guimarães, Hélio Penna

; Lobo, Suzana Margareth Ajeje

; Machado, Flávia Ribeiro

; Nunes, Michelle Silva

; Oliveira, Maura Salaroli de

; Parahiba, Suena Medeiros

; Rosa, Regis Goulart

; Santos, Vania Cristina Canuto

; Sobreira, Marcone Lima

; Veiga, Viviane Cordeiro

; Xavier, Ricardo Machado

; Zavascki, Alexandre Prehn

; Stein, Cinara

; Carvalho, Carlos Roberto Ribeiro de

Critical Care Science

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2023, Volume 35 N. 3 Pages 243 - 255

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To update the recommendations to support decisions regarding the pharmacological treatment of patients hospitalized with COVID-19 in Brazil. Methods: Experts, including representatives of the Ministry of Health and methodologists, created this guideline. The method used for the rapid development of guidelines was based on the adoption and/or adaptation of existing international guidelines (GRADE ADOLOPMENT) and supported by the e-COVID-19 RecMap platform. The quality of the evidence and the preparation of the recommendations followed the GRADE method. Results: Twenty-one recommendations were generated, including strong recommendations for the use of corticosteroids in patients using supplemental oxygen and conditional recommendations for the use of tocilizumab and baricitinib for patients on supplemental oxygen or on noninvasive ventilation and anticoagulants to prevent thromboembolism. Due to suspension of use authorization, it was not possible to make recommendations regarding the use of casirivimab + imdevimab. Strong recommendations against the use of azithromycin in patients without suspected bacterial infection, hydroxychloroquine, convalescent plasma, colchicine, and lopinavir + ritonavir and conditional recommendations against the use of ivermectin and remdesivir were made. Conclusion: New recommendations for the treatment of hospitalized patients with COVID-19 were generated, such as those for tocilizumab and baricitinib. Corticosteroids and prophylaxis for thromboembolism are still recommended, the latter with conditional recommendation. Several drugs were considered ineffective and should not be used to provide the best treatment according to the principles of evidence-based medicine and to promote resource economy.

RESUMO Objetivo: Atualizar as recomendações para embasar as decisões para o tratamento farmacológico de pacientes hospitalizados com COVID-19 no Brasil. Métodos: A elaboração desta diretriz foi feita por especialistas, incluindo representantes do Ministério da Saúde e metodologistas. O método utilizado para o desenvolvimento rápido de diretrizes baseou-se na adoção e/ou adaptação de diretrizes internacionais existentes (GRADE ADOLOPMENT) e contou com o apoio da plataforma e-COVID-19 RecMap. A qualidade das evidências e a elaboração das recomendações seguiram o método GRADE. Resultados: Chegaram-se a 21 recomendações, incluindo recomendações fortes quanto ao uso de corticosteroides em pacientes em uso de oxigênio suplementar e recomendações condicionais para o uso de tocilizumabe e baricitinibe, em pacientes com oxigênio suplementar ou ventilação não invasiva, e de anticoagulantes, para prevenção de tromboembolismo. Devido à suspensão da autorização de uso, não foi possível fazer recomendações para o tratamento com casirivimabe + imdevimabe. Foram feitas recomendações fortes contra o uso de azitromicina em pacientes sem suspeita de infecção bacteriana, hidroxicloroquina, plasma convalescente, colchicina e lopinavir + ritonavir, além de recomendações condicionais contra o uso de ivermectina e rendesivir. Conclusão: Foram criadas novas recomendações para o tratamento de pacientes hospitalizados com COVID-19, como as recomendações de tocilizumabe e baricitinibe. Ainda são recomendados corticosteroides e profilaxia contra tromboembolismo, esta em caráter condicional. Vários medicamentos foram considerados ineficazes e não devem ser usados, no intuito de proporcionar o melhor tratamento segundo os princípios da medicina baseada em evidências e promover a economia de recursos.

https://doi.org/10.5935/2965-2774.20230136-en

Plantas medicinais em quintais periurbanos: espaços de valorização da biodiversidade em São Miguel do Guamá, Pará
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Souza, Carlos Natham Machado de

; Silva, João Paulo de Jesus

; Santos, Janaira Almeida

; Lucas, Flávia Cristina Araújo

Interações (Campo Grande)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2023, Volume 24 N. 2 Pages 411 - 426

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Even with the growing advance in ethnobotanical studies, the amount of data that inventory the uses and knowledge associated with the biodiversity of medicinal plants existing in urban and periurban backyards in the Amazon region is still incipient. This article aimed to carry out a study of medicinal plants in rural backyards in the municipality of São Miguel do Guamá, Pará, valuing traditional knowledge and contributing to local biodiversity. Semi-structured interviews were carried out with 23 residents, selected by non-probabilistic sampling. The importance index (IVs) and the agreement on the main uses (CUP) were calculated. There were records of 80 medicinal recipes, from the use of 65 species. The most representative families were Asteraceae, Euphorbiaceae, and Lamiaceae. The importance value index was attributed to Melissa officinalis L. and to the agreement of main uses of Alternanthera sp., Melissa officinalis L., Plectranthus neochilus Schltr, and Chenopodium ambrosioides L. The highest values of agreement regarding corrected main uses (CUPc) were from Melissa officinalis L., Cymbopogon citratus (DC.) Stapf., and Alternanthera sp. Flu, fever, and diarrhea were the most prevalent health problems. The community preserves traditional medicine customs in health care and this translates into the way of life of these people and the intense circulation of medicinal plants in the backyards.

Resumen Incluso con el creciente avance de los estudios etnobotánicos, la cantidad de datos que hacen un inventario de los usos y conocimientos asociados a la biodiversidad de las plantas medicinales existentes en los patios traseros urbanos y periurbanos de la región amazónica es aún incipiente. Este estudio tuvo como objetivo realizar un estudio de plantas medicinales en patios rurales en el municipio de São Miguel do Guamá, Pará, valorando los conocimientos tradicionales y contribuyendo a la biodiversidad local. Se realizaron entrevistas semiestructuradas a 23 residentes, seleccionados mediante muestreo no probabilístico.

Resumo Mesmo com o avanço crescente nos estudos etnobotânicos, ainda é incipiente a quantidade de dados que inventariam os usos e saberes associados à biodiversidade das plantas medicinais existentes em quintais urbanos e periurbanos da região amazônica. No presente artigo, objetivou-se realizar estudo das plantas medicinais em quintais rurais no município de São Miguel do Guamá, Pará, valorizando os saberes tradicionais e contribuindo para o conhecimento da biodiversidade local. Entrevistas semiestruturadas foram realizadas com 23 moradores, selecionados por amostragem não probabilística. Foram calculados o índice de importância (IVs) e a concordância quanto aos usos principais (CUP). Houve registro de 80 receitas medicinais, a partir do uso de 65 espécies. As famílias mais representativas foram Asteraceae, Euphorbiaceae e Lamiaceae. O índice de valor de importância foi atribuído a Melissa officinalis L. e à concordância de usos principais de Alternanthera sp., Melissa officinalis L., Plectranthus neochilusSchltr e Chenopodium ambrosioides L. Os maiores valores de concordância quanto aos usos principais corrigidos (CUPc) foram de Melissa officinalis L., Cymbopogon citratus (DC.) Stapf. e Alternanthera sp. Gripe, febre e diarreia foram os problemas de saúde mais prevalentes. A comunidade preserva costumes da medicina tradicional em atenção à saúde, e isso traduz-se no modo de vida dessas pessoas e na intensa circulação de plantas medicinais nos quintais.

https://doi.org/10.20435/inter.v24i2.3490

Correlation between burden and sleep quality in informal caregivers of infants with orofacial cleft
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Batista, Nayara Tomazi

; Martinez, Ana Flávia

; Bom, Gesiane Cristina

; Farinha, Francely Tineli

; Prado, Priscila Capelato

; Trettene, Armando dos Santos

Revista Paulista de Pediatria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 41 elocation e2021352

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Avaliar a correlação entre a sobrecarga e a qualidade do sono em cuidadores de lactentes com fissura de lábio e/ou palato. Métodos: Estudo descritivo e transversal, realizado em um hospital público e terciário brasileiro entre março e setembro de 2020. Foram incluídos cuidadores informais principais de lactentes com fissura de lábio e/ou palato, alfabetizados e com idade igual ou superior a 18 anos. Utilizaram-se a Escala de Burden Interview e o Índice da Qualidade de Sono de Pittsburgh. A coleta de dados aconteceu durante a internação dos lactentes. Para a análise estatística, utilizaram-se as Correlações de Pearson e de Spearman, com nível de significância de 5%. Resultados: Participaram do estudo 31 cuidadores informais, dos quais prevaleceram as mães (n=28; 90%), com média de idade de 30 anos (desvio padrão — DP=7,5), pertencentes à classificação socioeconômica baixa (n=20; 64%), com ensino médio completo (n=19; 61%), casadas (58%), com dois filhos (n=15; 48%) e sem vínculo empregatício (n=18; 58%). Observou-se correlação moderada entre a qualidade do sono e a sobrecarga (r=0,39; p=0,032), e entre a sobrecarga e a qualidade subjetiva do sono (r=0,39; p=0,029), a latência do sono (r=0,43; p=0,017) e a disfunção durante o dia (r=0,49; p<0,001). Conclusões: Evidenciou-se que quanto maior a sobrecarga, menor foi a qualidade do sono. Os achados apontam a necessidade de planejar e implementar intervenções que minimizem a sobrecarga vivenciada por esses cuidadores informais, a fim de promover a qualidade do sono deles.

Abstract Objective: To evaluate the correlation between burden and sleep quality in caregivers of infants with cleft lip and/or palate. Methods: This descriptive cross-sectional study was carried out in a Brazilian tertiary public hospital between March and September 2020. The sample included the main informal, literate caregivers of infants with cleft lip and/or palate, aged 18 years or older. The instruments used were the Burden Interview Scale and the Pittsburgh Sleep Quality Index. Data were collected during the infants’ hospitalization. Statistical analysis adopted Pearson and Spearman correlations, with a 5% significance level. Results: A total of 31 informal caregivers participated in the study, most of them mothers (n=28; 90%), with a mean age of 30 years (standard deviation – SD=7.5), low socioeconomic status (n=20; 64%), who completed high school (n=19; 61%), were married (58%), had two children (n=15; 48%), and no employment relationship (n=18; 58%). A moderate correlation was found between sleep quality and burden (r=0.39; p=0.032) and between burden and subjective sleep quality (r=0.39; p=0.029), sleep latency (r=0.43; p=0.017), and daytime dysfunction (r=0.49; p<0.001). Conclusions: The study showed that the higher the burden, the lower the sleep quality. The findings indicate the need to plan and implement interventions to minimize the burden experienced by these informal caregivers in order to improve their sleep quality.

https://doi.org/10.1590/1984-0462/2023/41/2021352

Adaptation and indication of forage crops for agricultural production in sandy soils in western Bahia State, Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Simeão, Rosangela Maria

; Silva, Dagma Dionísia da

; Santos, Flávia Cristina dos

; Vilela, Lourival

; Silveira, Márcia Cristina Teixeira da

; Resende, Anna Carolina

; Albuquerque, Paulo Emílio Pereira de

Acta Scientiarum. Agronomy

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 45 elocation e56144

Abstract: En | Text: En | PDF: En

ABSTRACT. The diversity of soils and climate in Brazil imposes the need to evaluate the adaptation of fodder species to soil and climate conditions to guide producers and technicians in choosing the best alternatives for their region. The objective of this study was to evaluate and identify fodder cultivars for pasture and soil cover with tolerance to drought and high production in the sandy soils of southern Bahia, Brazil. The performance of 29 commercial cultivars of perennial and annual tropical forage species was evaluated in six cuts in 2019 and 2020. The green and dry mass yield per cut and the daily dry matter accumulation rate were evaluated considering the periods of water surplus and deficit and the drought tolerance index for each cultivar was estimated. Grass and legume cultivars showed differences in establishment, yield in the water surplus, and in the re-establishment after the water deficit. Based on the values of the drought tolerance index and in the dry mass daily yields before and after the water deficit, the cultivars adapted and indicated for regional continuous grazing were Xaraés, Marandu, Massai, Tanzânia, Paiaguás, and Zuri, in that order. The grasses B. ruziziensis and B. decumbens were indicated for use as cover plants after the harvest due to their high capacity of establishment and short-term production. The annual and perennial legume plants were also indicated for cover, and the combination of cultivars and their potential for straw in direct planting or use in integrated systems still need to be validated.

https://doi.org/10.4025/actasciagron.v45i1.56144

Awareness of the diagnosis, treatment, and control of diabetes mellitus in Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Tonaco, Luís Antônio Batista

; Velasquez-Melendez, Gustavo

; Moreira, Alexandra Dias

; Andrade, Flávia Cristina Drumond

; Malta, Deborah Carvalho

; Felisbino-Mendes, Mariana Santos

Revista de Saúde Pública

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 57 elocation 75

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Estimar as proporções dos indivíduos que têm conhecimento do diagnóstico, tratamento e controle do diabetes mellitus (DM) na população adulta brasileira. MÉTODO Este é um estudo transversal, com dados de amostra representativa da população brasileira, provenientes da Pesquisa Nacional de Saúde (PNS 2014/2015). Os desfechos foram definidos com base na medida de hemoglobina glicada (HbA1c), no diagnóstico autorreferido de DM e no uso de hipoglicemiantes ou de insulina. Estimou–se a proporção do conhecimento, tratamento e controle do DM de acordo com as características sociodemográficas, condição de saúde e de acesso aos serviços de saúde, e seus respectivos intervalos de 95% de confiança (IC95%). RESULTADOS A prevalência de DM na população brasileira foi 8,6% (IC95% 7,8–9,3), 68,2% (IC95% 63,9–72,3) tinham conhecimento do seu diagnóstico, 92,2% (IC95% 88,6–94,7) dos que tinham conhecimento realizam tratamento medicamentoso, e desses, 35,8% (IC95% 30,5–41,6) tinham os níveis de HbA1c controlados. As proporções de conhecimento, controle e tratamento foram menores nos homens, com idade de 18 a 39 anos, indivíduos que possuem baixa escolaridade, sem plano de saúde e beneficiários do Programa Bolsa Família. CONCLUSÃO Aproximadamente um em cada dez brasileiros apresenta DM. Um pouco mais da metade desta população tem conhecimento do seu diagnóstico, condição aferida por dosagem de HbA1c e diagnóstico clínico. Entre os que sabem, a grande maioria está sob tratamento medicamentoso. Porém, menos da metade destes tem seus níveis de HbA1c controlados. Cenários piores foram encontrados em subgrupos com alta vulnerabilidade social.

ABSTRACT OBJECTIVE To estimate the proportions of awareness, treatment, and control of diabetes mellitus (DM) in the Brazilian adult population. METHOD This is a cross-sectional study, with data from a representative sample of the Brazilian population, taken from the National Health Survey(PNS 2014/2015). Outcomes were defined based on glycated hemoglobin (HbA1c) measurements, self-reported DM diagnosis, and use of hypoglycemic agents or insulin. The proportion of DM awareness, treatment, and control was estimated according to sociodemographic characteristics, health conditions, and access to health services, and their respective 95% confidence intervals. RESULTS DM prevalence in the Brazilian population was of 8.6% (95%CI: 7.8–9.3): 68.2% (95%CI: 63.9–72.3) were aware of their diagnosis, 92.2% (95%CI: 88.6–94.7) of those who were aware were undergoing drug treatments, and, of these, 35.8% (95%CI: 30.5–41.6) had controlled HbA1c levels. The proportions of DM awareness, control, and treatment were lower in men aged 18 to 39 years, individuals with low education, without health insurance, and beneficiaries of the Bolsa Família program. CONCLUSION Approximately one in ten Brazilians has DM. A little more than half of this population is aware of their diagnosis, a condition measured by HbA1c dosage and clinical diagnosis. Among those who know, the vast majority are undergoing drug treatments. However, less than half of these have their HbA1c levels controlled. Worse scenarios were found in subgroups with high social vulnerability.

https://doi.org/10.11606/s1518-8787.2023057005167

Growth of long bones in European and Japanese quail from the 13th day of incubation to day 35 post-hatch
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

FIGUEROA, CHRISTIAN DOUGLAS N.

; CRUZ, FLAVIA K. DA

; KANEKO, ISABELLE N.

; BASAGLIA, RODRIGO A.

; OLIVEIRA, CARLOS ANTONIO L. DE

; IWAKI, LILIAN CRISTINA V.

; MURAKAMI, ALICE E.

; SANTOS, TATIANA C.

Anais da Academia Brasileira de Ciências

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 95 Suppl. 2 elocation e20220573

Abstract: En | Text: En | PDF: En

Abstract This study described the growth, morphometric, biomechanical, and chemical properties of the femur, tibiotarsus, and tarsometatarsus of European and Japanese quail. Analyses were performed at 13 and 15 days of incubation, at hatch, and at 4, 7, 10, 14, 21, 28, and 35 days post-hatch (n=6/subspecies/period). Bone specimens were analyzed by cone-beam computed tomography, biomechanical assays, chemical analyses, and histomorphometry. Variables were fitted by the Gompertz function and its derivative or assessed using the analysis of variance. Analysis of the derivative of Gompertz curves showed that the growth behavior of the tarsometatarsal bone was similar between quail subspecies, and the femur and tibiotarsus of European quail increased first in width and then in length, whereas the opposite occurred in Japanese quail. There was an interaction between quail subspecies and days of growth on femoral, tarsometatarsal, and tibiotarsal bone densities. Femoral and tibiotarsal cross-sectional areas were influenced by the interaction of quail subspecies and day of growth. Interaction effects were significant for breaking strength and phosphorus percentage. European and Japanese quail have different femoral and tibiotarsal growth patterns, especially in the first few days after hatching, whereas tarsometatarsal growth is similar between subspecies.

https://doi.org/10.1590/0001-3765202320220573

A medicina tradicional ribeirinha em vozes femininas
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Santos, Leonardo Silveira

; Santos, Ronize da Silva

; Moraes Junior, Manoel Ribeiro de

; Lucas, Flávia Cristina Araújo

; Custódio, Catarina

; Passos, Ladide de Souza

; Nascimento, Eliana do

Boletim do Museu Paraense Emílio Goeldi. Ciências Humanas

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 18 N. 1 elocation e20210068

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This article analyzes the biographies of three riverine women whose research is based on their social roles in providing care through traditional medicine. Their “life stories” show their own perceptions of how they construct and reconstruct their healing practices to address illnesses, always involving interactions with the environment and with religious traditions (most notably pajelança, Catholicism and Pentecostalism). The islands of Murutucum and Combu in Belém are the anthropogenic environments in which these specialists reside and work, watershed ecosystems for several rivers in Pará and a small portion of the Amazon River that drain into the Atlantic Ocean. The traditional cures present on these islands were analyzed from the narratives of these three specialists over a period of almost two years, with incursions, interviews and various types of in situ observations. The social and environmental framework and different religious expressions are seen to directly influence the diagnosis and therapeutic treatment proposed by these women, who have different yet complementary knowledge despite inhabiting the same ecosystem and being part of the same social group.

Resumo Este artigo analisa biografias de três mulheres ribeirinhas que têm como base investigativa os seus papéis sociais no cuidar através da medicina tradicional. Seus ‘relatos de vida’ transparecem as suas próprias percepções na construção e reconstrução de suas práticas de cura no enfrentamento de doenças, sempre levando em consideração as interações construídas com o meio e com tradições religiosas – dentre as quais se destacam a pajelança, o catolicismo e o pentecostalismo. As ilhas belenenses do Murutucum e do Combu são os ambientes antropogênicos nos quais as especialistas residem e atuam, ecossistemas de deságue hidrográfico de diversos rios paraenses e uma pequena parte do rio Amazonas no oceano Atlântico. As tipologias de curas tradicionais presentes nas ilhas foram analisadas a partir das narrativas destas três especialistas, num período de quase dois anos, com incursões, entrevistas e diversos tipos de observações in situ. Ao final, pode-se perceber que o quadro social e ambiental, bem como as diferentes expressões religiosas manifestas influenciam diretamente no diagnóstico e no tratamento terapêutico proposto por essas mulheres – que, apesar de habitarem o mesmo ecossistema e integrarem um grupo social comum, possuem saberes distintos, contudo, complementares.

https://doi.org/10.1590/2178-2547-bgoeldi-2021-0068

10.

Parental stress during pregnancy and maternity
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Ribeiro, Carine Sanches Zani

; Gondim, Ellen Cristina

; Scorzafave, Luiz Guilherme Dacar Silva

; Gomes-Sponholz, Flávia Azevedo

; Santos, Daniel Domingues dos

; Mello, Débora Falleiros de

Revista da Escola de Enfermagem da USP

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 57 elocation e20220351

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: To identify factors related to parental stress of women during pregnancy and the child’s first month of life. Method: Prospective longitudinal study in two stages. Analysis of home interviews with 121 participants, Gestational Stress Scale, and Parental Stress Scale. Fisher’s exact test, Spearman’s correlation, and linear and logistic multivariate regression were applied, with p < 0.05. Results: Most of the participants were between 18 and 35 years old, had 11 to 13 years of education, had no paid work, had a partner, usually the child’s father, planned pregnancy, were multiparous, and underwent prenatal care. During pregnancy, 67.8% had stress. In the first month after the child’s birth, most had low parental stress (52.1%). High parental stress correlated with some gestational stress. Planning pregnancy decreased parental stress. Conclusion: Gestational and parental stress in the child’s first month of life were correlated and pregnancy planning was a factor that reduced stress levels. Timely actions to reduce parental stress are essential for parenting and the child’s overall health.

RESUMEN Objetivo: Identificar factores relacionados con el estrés parental de la mujer durante el embarazo y el primer mes de vida del niño. Método: Estudio longitudinal prospectivo en dos etapas. Análisis de entrevistas domiciliarias con 121 participantes, Escala de Estrés Gestacional y Estrés Parental. Se aplicó la prueba exacta de Fisher, correlación de Spearman y regresión multivariada lineal y logística, con p < 0,05. Resultados: La mayoría de las participantes tenía entre 18 y 35 años, tenía entre 11 y 13 años de escolaridad, no tenía trabajo remunerado, tenía pareja, generalmente el padre del niño, embarazo planificado, multípara y realizó control prenatal. Durante el embarazo, el 67,8% tuvo estrés. En el primer mes después del nacimiento del hijo, la mayoría presentó bajo estrés parental (52,1%). El estrés parental alto se correlacionó con algo de estrés gestacional. La planificación del embarazo disminuyó el estrés parental. Conclusión: El estrés gestacional y parental en el primer mes de vida del niño se correlacionaron y la planificación del embarazo fue un factor en la reducción de los niveles de estrés. Las acciones oportunas para reducir el estrés parental son esenciales para la responsabilidad parental y la salud general del niño.

RESUMO Objetivo: Identificar fatores relacionados ao estresse parental de mulheres na gestação e primeiro mês de vida da criança. Método: Estudo longitudinal prospectivo em duas etapas. Análise de entrevistas em domicílio com 121 participantes, Escala de Estresse Gestacional e de Estresse Parental. Aplicados teste exato de Fisher, correlação de Spearman e regressão multivariada linear e logística, com p < 0,05. Resultados: A maior parcela das participantes tinha entre 18 e 35 anos, 11 a 13 anos de estudo, sem trabalho remunerado, com companheiro, geralmente o pai da criança, gestação planejada, multípara e realização do pré-natal. Na gestação, 67,8% apresentaram estresse. No primeiro mês após o nascimento do filho, a maioria teve baixo estresse parental (52,1%). Estresse parental alto apresentou correlação com algum estresse gestacional. Planejar a gestação diminuiu o estresse parental. Conclusão: Estresse gestacional e parental no primeiro mês de vida da criança foram correlacionados e o planejamento da gestação constituiu fator de diminuição dos níveis de estresse. Ações oportunas para reduzir o estresse parental são fundamentais para a parentalidade e saúde integral da criança.

https://doi.org/10.1590/1980-220x-reeusp-2022-0351en

11.

Prevalence of breastfeeding among indigenous peoples of the Triple Frontier: Brazil, Argentina and Paraguay
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Pereira, Bianca da Silva Alcantara

; Zilly, Adriana

; Monteiro, Juliana Cristina dos Santos

; Barbosa, Nayara Gonçalves

; Gomes-Sponholz, Flávia Azevedo

Revista Brasileira de Saúde Materno Infantil

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 23 elocation e20200237

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objectives: to verify the prevalence of breastfeeding and the children’s nutritional status of indigenous origin up to two years of age in the triple frontier region: Brazil, Argentina and Paraguay. Methods: data from the Sistema de Vigilância Nutricional e Alimentar Indígena (Indigenous Food and Nutrition Surveillance System) were analyzed, being a cross-sectional and descriptive study. The survey was carried out in 2018, with data referring to 2017. Registrations of indigenous children of both sexes,aged zero to two years old were included. Data were extracted from the indigenous children’s follow-up map. The prevalence of breastfeeding and complementary feeding was evaluated. Results: the prevalence of exclusive breastfeeding in children under six months of age was 93.4% and complementary breastfeeding was 6.5%. The prevalence of complementary breastfeeding after six months was 71.6% and exclusive breastfeeding after six months was 28.3%. Regarding social benefits, 30.3% of the families accumulated two types of social benefits. Conclusions: the prevalence of exclusive breastfeeding was high and surpassed the national prevalence in the first semester of life, there was no early weaning.

Resumo Objetivos: verificar a prevalência do aleitamento materno e estado nutricional de crianças de origem indígena até dois anos de idade na região de tríplice fronteira: Brasil, Argentina e Paraguai. Métodos: foram analisados dados do Sistema de Vigilância Nutricional e Alimentar Indígena, sendo um estudo transversal e descritivo. A pesquisa foi realizada em 2018, com dados referentes à 2017. Foram incluídos registros de crianças indígenas de zero a dois anos de idade, de ambos os sexos. Os dados foram extraídos do mapa de acompanhamento de crianças indígenas. Foi avaliada a prevalência do aleitamento materno e alimentação complementar. Resultados: a prevalência de aleitamento materno exclusivo em menores de seis meses foi de 93,4% e do aleitamento materno complementado foi de 6,5%. A prevalência do aleitamento materno complementado após seis meses foi de 71,6% e do aleitamento materno exclusivo após seis meses foi de 28,3%. Com relação à classificação de peso para a idade, 80,5% dos registros mostraram crianças com peso adequado para a idade. Em relação aos benefícios sociais, 30,3% das famílias acumulavam dois tipos de benefícios sociais. Conclusões: a prevalência de aleitamento materno exclusivo foi alta e superam prevalência nacional no primeiro semestre de vida, não houve desmame precoce.

https://doi.org/10.1590/1806-93042023000000237-en

12.

Trend in hospitalizations due to ambulatory care-sensitive conditions in the Federal District
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Horta, Isabel Pintas Marques

; Andrade, Flávia Reis de

; Santos, Lorena da Silva Luz

; Sousa, Naira Pereira de

; Lima, Luciano Ramos de

; Rehem, Tania Cristina Morais Santa Bárbara

Revista Brasileira de Enfermagem

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 76 N. 2 elocation e20220351

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to analyze the trend, according to sex, of Ambulatory Care-Sensitive Conditions in the Primary Health Care of the Federal District, from 2009 to 2019. Methods: ecological trend study using ACSC hospitalization data available in the Hospitalization System of the Single Health System. The Prais-Winsten method was used to calculate the annual rate variation, expressed in percentages. The dependent variable was the logarithm of the rates, and the independent one, the years in the time series. Results: the Federal District registered 2,103,951 general hospitalizations, 16.4% of which were due to Ambulatory Care-Sensitive Conditions. Males had a higher rate of hospitalization in the period, and both sexes showed a stationary trend. Conclusions: the time trend of Ambulatory Care- Sensitive Conditions was stationary, but further studies are necessary regarding primary health care coverage.

RESUMEN Objetivos: analizar tendencia de Internaciones por Condiciones Sensibles a la Atención Primaria por sexo en Distrito Federal desde 2009 a 2019. Métodos: estudio ecológico de tendencia con datos de ICSAP disponibles en el Sistema de Internaciones Hospitalarias del Sistema Único de Salud. Utilizado método de Prais-Winsten para el cálculo de la variación porcentual anual de las tasas. La variable dependiente fue el logaritmo de las tasas, y la independiente, los años de la serie temporal. Resultados: Distrito Federal registró 2.103.951 internaciones generales, siendo 16,4% Internaciones por Condiciones Sensibles a la Atención Primaria. El sexo masculino obtuvo la mayor tasa de internación en todo el periodo y hubo tendencia estacionaria tanto para el sexo masculino mientras el femenino. Conclusiones: las tendencias temporales de las Internaciones por Condiciones Sensibles a la Atención Ambulatoria mostradas estacionarias, pero resaltada la necesidad de estudios de correlación con la cobertura de la atención primaria de salud.

RESUMO Objetivos: analisar a tendência das Internações por Condições Sensíveis à Atenção Primária por sexo no Distrito Federal, no período de 2009 a 2019. Métodos: estudo ecológico de tendência com dados de ICSAP disponíveis no Sistema de Internações Hospitalares do Sistema Único de Saúde. Utilizou-se o método de Prais-Winsten para o cálculo da variação percentual anual das taxas. A variável dependente foi o logaritmo das taxas; e a variável independente, os anos da série temporal. Resultados: o Distrito Federal registrou 2.103.951 internações gerais, sendo 16,4% Internações por Condições Sensíveis à Atenção Primária. O sexo masculino obteve a maior taxa de internação em todo o período, e houve tendência estacionária tanto para o sexo masculino quanto para o sexo feminino. Conclusões: as tendências temporais das Internações por Condições Sensíveis à Atenção Primária mostraram-se estacionárias, porém ressalta-se a necessidade de estudos de correlação com a cobertura da Atenção Primária à Saúde.

https://doi.org/10.1590/0034-7167-2022-0351

13.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

14.

Human papillomavirus prevalence and frequency of sexually transmitted diseases in encarcered women by self-sampling approach
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Pereira, Hilka Flávia Barra Espírito Santo Alves

; Nunes, Gabriel Pacífico Seabra

; Pereira, Henrique Vieira

; Silva, Karollina Deon e

; Olenchi, Maiara Magri Pereira

; Silva, Thais Cristina Fonseca da

; Aguiar, Valbécia Tavares de

; Costa, Valéria Santos da

; Torres, Kátia Luz

; Silva Filho, Agnaldo Lopes da

Revista da Associação Médica Brasileira

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 69 N. 8 elocation e20230204

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: This study aimed to assess the sociodemographic and clinical profile of women deprived of their liberty and to identify the prevalence of sexually transmitted diseases and human papillomavirus through self-sampling samples. METHODS: This is an epidemiological, cross-sectional, observational, and descriptive study of the prevalence and correlation of the diagnosis of human papillomavirus infection in 268 encarcered women in Amazonas submitted to self-sampling from June 2019 to September 2020 using the genotyping analysis. Patients with positive and inconclusive results were evaluated by commercialized PCR to detect pathogens causing sexually transmitted diseases. The sample size used was based on a convenience sample. RESULTS: In 268 women, human papillomavirus DNA was detected in 87 (32.5%) of them. Sexually transmitted diseases were detected in 30 (34.48%) of the 87 women with a positive or inconclusive result for human papillomavirus. Women with more than three pregnancies had a higher risk of human papillomavirus detection (p=0.004). CONCLUSION: The prevalence of human papillomavirus and other sexually transmitted diseases in encarcered women in Amazonas is 32.5 and 34.48%, respectively. Most women were single (60.4%) and reported having had more than 15 partners (90.8%).

https://doi.org/10.1590/1806-9282.20230204

15.

Cognitive dysfunction in patients with childhood-onset systemic lupus erythematosus may impact treatment
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Santos, Flávia Patrícia Sena Teixeira

; Ferreira, Gilda Aparecida

; Paula, Jonas Jadim de

; Souza, Kalline Cristina Prata de

; Silva, Sandro Luiz Cançado

; Correa, Humberto

Advances in Rheumatology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 63 elocation 18

Abstract: En | Text: En | PDF: En

Abstract Background Cognitive dysfunction (CD) is a widespread manifestation in adult systemic lupus erythematosus (SLE) patients, but this subject is rarely examined in patients with childhood-onset SLE (cSLE). This study aimed to assess the frequency of CD, its associations with lupus clinical manifestations and its impact on the health-related quality of life (HRQL) in young adult cSLE patients. Methods We evaluated 39 cSLE patients older than 18 years. They underwent a rheumatologic evaluation and extensive neuropsychological assessment, encompassing all cognitive domains described by the American College of Rheumatology. HRQL was assessed with the WHOOQOL-BREEF, General Activities of Daily Living Scale (GADL) and Systemic Lupus Erythematosus-specific quality-of-life instrument (SLEQOL). The activity of SLE was evaluated with the modified sle disease activity index (sledai-2k). Results Impairment in at least one cognitive domain was found in 35 (87.2%) patients. The most compromised domains were attention (64.1%), memory (46.2%), and executive functions (38.5%). Patients with cognitive impairment were older, had more accumulated damage and had worse socioeconomic status. Regarding the association between cognitive dysfunction and HRQL, memory impairment was correlated with worse environmental perception and a worse relationship with the treatment. Conclusion In this study, the frequency of CD in cSLE patients was as high as that in the adult SLE population. CD can significantly impact the response of cSLE patients to treatment, justifying preventive measures in the care of this population.

https://doi.org/10.1186/s42358-023-00300-8

Showing

itens per page

Page of 15 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »