Search | SciELO

ABSTRACT Background Several therapies have been used or proposed for the treatment of COVID-19, although their effectiveness and safety have not been properly evaluated. The purpose of this document is to provide recommendations to support decisions about the drug treatment of outpatients with COVID-19 in Brazil. Methods A panel consisting of experts from different clinical fields, representatives of the Brazilian Ministry of Health, and methodologists (37 members in total) was responsible for preparing these guidelines. A rapid guideline development method was used, based on the adoption and/or adaptation of recommendations from existing international guidelines combined with additional structured searches for primary studies and new recommendations whenever necessary (GRADE-ADOLOPMENT). The rating of quality of evidence and the drafting of recommendations followed the GRADE method. Results Ten technologies were evaluated, and 10 recommendations were prepared. Recommendations were made against the use of anticoagulants, azithromycin, budesonide, colchicine, corticosteroids, hydroxychloroquine/chloroquine alone or combined with azithromycin, ivermectin, nitazoxanide, and convalescent plasma. It was not possible to make a recommendation regarding the use of monoclonal antibodies in outpatients, as their benefit is uncertain and their cost is high, with limitations of availability and implementation. Conclusion To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.

https://doi.org/10.1016/j.bjid.2022.102347

Orange essential oil in the diet of broilers: performance, organ biometrics, bone characteristics, and intestinal morphometry
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Souza, Christiane Silva

; Vieites, Flávio Medeiros

; Justino, Lucas Rodrigo

; Lima, Marcos Fabio de

; Chaves, Amália Saturnino

; Minafra, Cibele Silva

; Lima, Cristina Amorim Ribeiro de

Revista Brasileira de Zootecnia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2021, Volume 50 elocation e20200097

Abstract: En | Text: En | PDF: En

ABSTRACT Growth performance, organ biometrics, bone characteristics, and intestinal morphometry were evaluated in broilers fed a diet containing orange (Citrus sinensis L.) essential oil. A completely randomized design was used, with five treatments with orange essential oil (0, 100, 200, 300, and 400 mg kg−1 diet) and six replications with 20 birds per experimental unit. In the pre-starter phase, feed intake and weight gain of all birds linearly increased, while feed conversion decreased with the addition of orange essential oil in the feed. At day 21, bone density (Seedor Index) and body weight were higher in the birds that received the maximum level of essential oil (400 mg kg−1) compared with those not treated with essential oil. The observed effects resulted from the better functioning of the physiological mechanisms of digestion and absorption of nutrients, characterized by the increase in villus height. Glycemia and weights of gastrointestinal tract organs of broilers at 21 days of age were not influenced by the evaluated essential oil. The results show that the addition of phytogenic additives to the diet does not cause any physiological impairment in birds.

https://doi.org/10.37496/rbz5020200097 532 downloads

Standardized ileal phosphorus digestibility of meat and bone meal and poultry byproduct meal for broilers
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Dilelis, Felipe

; Freitas, Leonardo Willian de

; Quaresma, Débora Vaccari

; Machado, Noédson de Jesus Beltrão

; Reis, Túlio Leite

; Souza, Christiane Silva

; Lima, Cristina Amorim Ribeiro de

Revista Brasileira de Zootecnia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2021, Volume 50 elocation e20200086

Abstract: En | Text: En | PDF: En

ABSTRACT Two experiments were conducted using direct method to determine the standardized ileal phosphorus (P) digestibility coefficient (SIPDC) of meat and bone meal (MBM) and poultry byproduct meal (PBM) for broilers. In the first experiment, three MBM from different batches were evaluated, with four treatments (MBMI, MBMII, MBMIII, and a P-free diet) and nine replicates of seven birds each, totaling 252 birds distributed across a completely randomized design. The P-free diet was used to determine endogenous P losses. Titanium dioxide (5 g kg−1) was used as an indigestible indicator. In the second experiment, three PBM from different batches were evaluated, with 189 birds distributed over three treatments (PBMI, PBMII, and PBMIII) and nine replicates of seven birds each. These two experiments were conducted when birds were 19-22 days old. The birds were euthanized to collect the ileal content. Using the P-free diet, endogenous P losses were determined at 94.9 mg kg−1 dry matter intake. Standardized ileal P digestibility of MBMI (0.65) and MBMIII (0.69) was higher compared with MBMII (0.49). The SIPDC determined for three PBM sources were similar and 0.96, 0.96, and 0.93 for PBMI, PBMII, and PBMIII, respectively. The present study demonstrates that P in MBM is not as available as it is believed and that the variability between batches should be considered by nutritionists, while PBM can be considered an excellent P source to broiler diets.

https://doi.org/10.37496/rbz5020200086 443 downloads

Moderada endemicidade da infecção pelo vírus linfotrópico-T humano na região metropolitana de Belém, Pará, Brasil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Ingrid Christiane

; Pinheiro, Bruna Teles

; Nobre, Akim Felipe Santos

; Coelho, Jaciana Lima

; Pereira, Cássia Cristine Costa

; Ferreira, Louise de Souza Canto

; Almeida, Camila Pâmela Santos de

; Viana, Maria de Nazaré do Socorro de Almeida

; Almeida, Danilo Souza de

; Falcão, Jairo Ribeiro

; Santos, Yago Costa Vasconcelos dos

; Araújo, Marcos William Leão de

; Borges, Mariza da Silva

; Nascimento, Lisandra Duarte

; Valentim, Lorena Saldanha

; Casseb, Jorge Simão do Rosario

; Costa, Carlos Araújo da

; Sousa, Maísa Silva de

Revista Brasileira de Epidemiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2018, Volume 21 elocation e180018

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Introdução: A disseminação da infecção pelo vírus linfotrópico-T humano (HTLV) em famílias da área metropolitana de Belém, Pará, Brasil, e a ausência de estudos na população em geral requisitam investigações que esclareçam melhor a sua prevalência na região. Metodologia: Foi realizada pesquisa de anticorpos anti-HTLV-1/HTLV-2 em indivíduos adultos transeuntes de logradouros públicos de Belém, entre novembro de 2014 e novembro de 2015. A infecção foi confirmada por pesquisa de DNA proviral e foi realizada avaliação clínica e investigação intrafamiliar dos infectados. Resultados: Dos 1.059 indivíduos investigados, 21 (2,0%) apresentaram amostras sororeagentes, 15 (1,4%) confirmados para HTLV-1, 5 (0,5%) para HTLV-2 e o DNA proviral foi indetectável em 1 caso. A média de idade dos infectados (57,2) foi maior que a dos não infectados (46,2) (p = 0,0010). A infecção aumentou com a idade e se destacou nos indivíduos com renda familiar menor ou igual a um salário mínimo. A transmissão intrafamiliar parece ter ocorrido em todas as famílias investigadas. Dentre os portadores de HTLV-1, 30% (3/10) já apresentavam algum sintoma relacionado à infecção. Discussão: O aumento da infecção de acordo com a idade pode ocorrer por soroconversão tardia de infecção pré-adquirida ou pelo risco cumulativo de novas infecções, sobretudo em mulheres. Conclusão: A infecção por HTLV demonstrou moderada prevalência na população estudada, com predomínio do HTLV-1. Essa mostrou-se associada à baixa renda e ao aumento da idade das mulheres. Também apresentou disseminação intrafamiliar e negligência no diagnóstico das doenças associadas.

ABSTRACT: Introduction: The spread of the HTLV infection in families living in the metropolitan area of Belém, Pará, Brazil, and the lack of studies in the general population requires studies to better understand its prevalence in the region. Methods: An anti-HTLV-1/HTLV-2 antibodies test was carried out on random adults in public places in Belém between November 2014 and November 2015. A proviral DNA test detected if the person was infected, and then a clinical evaluation and an intrafamilial investigation were carried out. Results: Of the 1059 individuals being investigated, 21 (2.0%) had seroreagent samples, 15 (1.4%) had HTLV-1, 5 (0.5%) had HTLV-2, and proviral DNA was undetectable in one case. The mean age of the infected people (57.2) was higher than that of those that were uninfected (46.2) (p = 0.0010). The prevalence of infection increased with age, especially in individuals with a family income equal to or less than a minimum wage. Intrafamilial transmission seems to have occurred in all of the families being studied. Among the patients with HTLV-1, 30% (3/10) already had some symptom related to the infection. Discussion: The increase in prevalence rates according to age may be due to late seroconversion of a previously acquired infection, or the cumulative risk of new infections, especially in women. Conclusion: There was a moderate prevalence of the HTLV infection among adult individuals from the metropolitan area of Belém, with a predominance of HTLV-1. This infection was associated with low income and increasingly older women. It also presented intrafamily spread and negligence in the diagnosis of associated diseases.

https://doi.org/10.1590/1980-549720180018 17 downloads

Moderada endemicidade da infecção pelo vírus linfotrópico-T humano na região metropolitana de Belém, Pará, Brasil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Ingrid Christiane

; Pinheiro, Bruna Teles

; Nobre, Akim Felipe Santos

; Coelho, Jaciana Lima

; Pereira, Cássia Cristine Costa

; Ferreira, Louise de Souza Canto

; Almeida, Camila Pâmela Santos de

; Viana, Maria de Nazaré do Socorro de Almeida

; Almeida, Danilo Souza de

; Falcão, Jairo Ribeiro

; Santos, Yago Costa Vasconcelos dos

; Araújo, Marcos William Leão de

; Borges, Mariza da Silva

; Nascimento, Lisandra Duarte

; Valentim, Lorena Saldanha

; Casseb, Jorge Simão do Rosario

; Costa, Carlos Araújo da

; Sousa, Maísa Silva de

Revista Brasileira de Epidemiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2018, Volume 21 elocation e180018

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720180018 2846 downloads

Efficient degradation of solid yeast biomass from ethanol industry by Fenton and UV-Fenton processes applying multivariate analysis
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Labuto, Geórgia

; Silva, Lilia Ribeiro da

; Silva, Heron Dominguez Torres da

; Carrilho, Elma Neide Vasconcelos Martins

; Goncalves, Norberto Sanches

; Rodrigues, Christiane de Arruda

Revista Ambiente & Água

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2017, Volume 12 N. 6 Pages 946 - 963

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Resíduos agro-industriais orgânicos têm sido utilizados com sucesso como biossorventes e podem impulsionar a economia promovendo novos usos para os mesmos. Contudo, o destino do resíduo sólido gerado pelo biossorvente após a sorção de contaminantes tem sido uma limitação à aplicação em larga escala de tais materiais como alternativa ao tratamento de águas e águas residuais. Processos oxidativos avançados podem ser uma alternativa para converter o material biossorvente, juntamente com contaminantes orgânicos adsorvidos, em compostos amigáveis ao meio ambiente adequados para descarte. No presente trabalho, planejamento experimental foi utilizado para avaliar a degradação da biomassa de levedura (YB) da indústria de álcool, uma biomassa empregada como biossorvente. Através de processos Fenton e UV-Fenton, a eficiência da degradação foi monitorada de acordo com a massa degradada (DM) e o carbono orgânico total (TOC) remanescente na solução. ANOVA mostrou que os processos de degradação são adequados, com erro de 9,7% para os efeitos e os meios de interação para o modelo empregado para DM. A condução de degradação empregando as melhores condições previstas pelo modelo teórico (60 min, 25 g de YB, pH 3, 8.000 mg L-1 de H2O2 e 40 mg L-1 de Fe2+) com irradiação UV de 30 W resultou numa redução em massa de YB de 72 ± 2% com um TOC de 30 ± 2%. Isto sugere que um processo oxidativo avançado é uma alternativa para a degradação de um biossorvente sólido após sorção.

Abstract Organic agro-industrial residues have been successfully used as biosorbents and promoting new uses from agricultural wastes benefits the economy. However, the allocation of a solid waste biosorbent after the sorption of contaminants has limited their effective application on a large scale as an alternative treatment of water and wastewaters. One solution could be degradation to convert the biosorbent material and adsorbed organic contaminants into environmental friendly compounds suitable for discharge. This study used an experimental design to evaluate the Fenton degradation of yeast biomass (YB) from the alcohol industry as a potential biosorbent. The efficiency of degradation was monitored according to the degraded mass (DM) and total organic carbon (TOC) remaining in the solution. The ANOVA showed an error of 9.7% for the effects and the media of interaction for the employed model for DM. Conducting the experiments with the best-predicted conditions (60 min, 25 g of YB, pH 3, 8,000 mg L-1 H2O2 and 40 mg L-1 Fe2+) with 30 W UV irradiation resulted in a YB reduction of 72 ( 2% with a TOC of 30 ( 2%. This suggests that an advanced oxidative process is an alternative for degradation of a biosorbent after sorption.

https://doi.org/10.4136/ambi-agua.2124 1005 downloads

DENGUE DURING PREGNANCY: ASSOCIATION WITH LOW BIRTH WEIGHT AND PREMATURITY
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

RIBEIRO, Christiane Fernandes

; LOPES, Vânia Glória Silami

; Brasil, Patricia

; Silva, Licinio Esmeraldo da

; RIBEIRO, Pedro Henrique Fernandes Josephson

; UGENTI, Luca Cipriani

; NOGUEIRA, Rita Maria Ribeiro

Revista do Instituto de Medicina Tropical de São Paulo

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2016, Volume 58 elocation 8

Abstract: En | Text: En | PDF: En

The aim of this study was to evaluate the effects of dengue virus infection during pregnancy and its correlation with low birth weight, prematurity, and asphyxia. A non-concurrent cohort study reveals the association of dengue during pregnancy with prematurity and low birth weight, when birth occurred during the maternal-fetal viremia period (p = 0.016 and p < 0.0001, respectively).

https://doi.org/10.1590/S1678-9946201658008 3498 downloads

Methodology for determining rom size distribution
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Christiane Ribeiro da

; Souza, Vládia C. G. de

; Koppe, Jair C.

Rem: Revista Escola de Minas

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2014, Volume 67 N. 4 Pages 405 - 412

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A metodologia para determinar a curva granulométrica de ROM foi desenvolvida em uma mina de ferro localizada no Brasil. O tamanho dos blocos maiores foi determinado a partir de fotografias, por meio das quais foi definida uma escala para analisar as dimensões dos blocos (comprimento e área). Isso foi implementado de acordo com um protocolo de amostragem específico, que envolve etapas de divisão e de homogeneização in situ de uma considerável quantidade de minério (cerca de 259 toneladas). Durante o processo de amostragem, os blocos maiores foram segregados, para mensuração, por análise de imagens, enquanto que os de menor tamanho foram peneirados. A metodologia foi desenvolvida para avaliar, inicialmente, o desempenho de um britador giratório, alimentado por basculamento direto, a partir de caminhões. Condições operacionais desse tipo de equipamento, tais como configurações das aberturas de posição aberta (APA) e de posição fechada (APF), podem ser ajustadas previamente, permitindo, assim, a obtenção de diferentes distribuições de tamanho de produto. A variabilidade de tamanho dos fragmentos afeta diretamente os estágios seguintes de britagem, podendo causar um aumento significativo na carga circulante do circuito. Isto leva a uma diminuição da produtividade e recuperação nas etapas posteriores. Os resultados de granulometria de ROM mostraram erros de reprodutibilidade e viés desprezíveis para o protocolo de amostragem desenvolvido, aplicado em itabirito friável.

A methodology to determine the size distribution curve of the ROM was developed in a Brazilian iron ore mine. The size of the larger fragments was determined taking photographs and setting the scale of the images to analyze their dimensions (length of their edges and areas). This was implemented according to a specific protocol of sampling that involves split and homogenization stages in situ of a considerable quantity of ore (about 259 metric tonnes). During the sampling process, larger fragments were separated and smaller size material was screened. The methodology was developed initially in order to preview the performance of a primary gyratory crusher that is fed directly from trucks. Operational conditions of the equipment such as closed and open-side settings could be adjusted previously, obtaining different product size distributions. Variability of size of the fragments affects subsequent stages of crushing and can increase circulating load in the circuit. This leads to a decrease of productivity or recovery of the ore dressing. The results showed insignificant errors of accuracy and reproducibility of the sampling protocol when applied to friable itabirite rocks.

https://doi.org/10.1590/0370-44672014670184 3180 downloads

Occurrences of Eimeria spp. and gastrointestinal nematodes in dairy calves in southern Minas Gerais, Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Bruhn, Fábio Raphael Pascoti

; Silva Júnior, Fidelis Antônio

; Carvalho, André Henrique de Oliveira

; Orlando, Débora Ribeiro

; Rocha, Christiane Maria Barcellos Magalhães da

; Guimarães, Antônio Marcos

Revista Brasileira de Parasitologia Veterinária

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2012, Volume 21 N. 2 Pages 171 - 175

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objetivo deste estudo foi determinar a frequência e os fatores associados à infecção por Eimeria spp. e nematódeos gastrintestinais, em 356 bezerras provenientes de 20 rebanhos leiteiros, localizados no sul de Minas Gerais, Brasil. Foram identificadas dez espécies de Eimeria spp., sendo E. bovis (37,6%) e E. zuernii (17,9%) as mais frequentes. Nas coproculturas, foram recuperados quatro gêneros de nematódeos gastrintestinais, sendo os mais frequentes Cooperia spp. (74,6%) e Haemonchus spp. (19,4%).Variáveis relacionadas a um maior nível de tecnificação das propriedades leiteiras apresentaram associação significativa (p < 0,05), com maiores contagens de OoPG e OPG, e são discutidas neste estudo.

The aim of this cross-sectional observational study was to determine the frequency and factors associated with infection by Eimeria spp. and gastrointestinal nematodes in 356 calves on 20 dairy farms located in southern Minas Gerais, Brazil. Ten species of Eimeria spp. were identified, of which E. bovis (37.6%) and E. zuernii (17.9%) were the most frequent. From fecal cultures, four genera of gastrointestinal nematodes were recovered, of which Cooperia spp. (74.6%) and Haemonchus (19.4%) were the most frequent. Variables relating to higher levels of technology used on dairy farms showed a significant association (p < 0.05) with higher OPG and EPG counts, and are discussed in this study.

2093 downloads

Showing

itens per page

Page of 1 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »