Resumo Objetivo Esta meta-análise teve como objetivo avaliar a sensibilidade e especificidade da colonografia por tomografia computadorizada na detecção de pólipos colorretais. Métodos Foi realizada uma pesquisa bibliográfica nas bases de dados da PubMed e da Web of Science. Resultados Um total de 1.872 pacientes, 57,2% homens e 42,8% mulheres, com idades entre 49 a 82 anos de idade (média de 59,7 ± 5,3 anos) foram incluídos nesta meta análise. A sensibilidade da colonografia por tomografia computadorizada foi estimada em 88,4% (46,3-95,7%; coeficiente de variância [CV]=28,5%) e a especificidade em 73,6% (47,4%-100,0%; CV=37,5%). Para lesões de até 9mm, a sensibilidade foi de 82,5% (62,0-99,9%; CV=25,1%) e a especificidade de 79,2% (32,0-98,0%; CV=22,9%). Para lesõesmaiores que 9mm, a sensibilidade foi de 90,2% (64,0-100,0%; CV=7,4%) e a especificidade de 94,7% (80,0-100,0%; CV=6,2%). Não houve diferença estatisticamente significante entre as sensibilidades por tamanho da lesão (p=0,0958), porém a especificidade foi maior em lesões acima de 9mm (p<0,0001). Conclusão A maioria dos estudos analisados no presente trabalho foi realizada antes de 2010, cerca de uma década depois que a colonografia por tomografia computadorizada passou a ser indicada como método de triagem pelas diretrizes europeias e americanas. Portanto, são necessários mais estudos com o objetivo de analisar a técnica apósmaiores avanços tecnológicos, o que poderia levar ao desenvolvimento de dispositivos mais modernos.

Abstract Objective This metanalysis aimed to evaluate the sensitivity and specificity of computed tomography colonography in colorectal polyp detection. Methods A literature search was performed in the PubMed and Web of Science databases. Results A total of 1,872 patients (males 57.2%, females 42.8%) aged 49 to 82 years old (mean age 59.7 ± 5.3 years) were included in this metanalysis. The estimated sensitivity of computed tomography colonography was 88.4% (46.3-95.7%, coefficient of variation [CV]=28.5%) and the estimated specificity was 73.6% (47.4-100.0%, CV=37.5%). For lesions up to 9mm, the sensitivity was 82.5% (62.0-99.9%, CV =25.1%) and the specificity was 79.2% (32.0-98.0%, CV=22.9%). For lesions>9mm, the sensitivity was 90.2% (64.0-100.0%, CV=7.4%) and the specificity was 94.7% (80.0-100.0%, CV=6.2%). No statistically significant differences in sensitivity according to the size of the lesion were found (p=0.0958); however, the specificity was higher for lesions>9mm (p<0.0001). Conclusions Most of the studies analyzed in the present work were conducted before 2010, which is about a decade after computed tomography colonography started being indicated as a screening method by European and American guidelines. Therefore, more studies aimed at analyzing the technique after further technological advancements are necessary, which could lead to the development of more modern devices.

Abstract INTRODUCTION: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. METHODS: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. RESULTS: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells. CONCLUSIONS: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells.

Resumo A meta 6 da Estratégia Global para a Conservação de Plantas (GSPC) da Convenção de Diversidade Biológica das Nações Unidas (CDB) propõe que, em 2020, pelo menos 75% das terras destinadas à produção em cada setor serão manejadas de forma sustentável, em alinhamento com a conservação da diversidade vegetal. A meta 11 determina que em 2020 nenhuma espécie da flora silvestre será ameaçada pelo comércio internacional. Ambas as metas, portanto, são relacionadas à produção, consumo e comércio internacional, que se espera que tenham uma base sustentável, para que as metas sejam alcançadas. Esse artigo examina os avanços do Brasil em direção ao alcance dessas metas, focalizando em três setores econômicos (agricultura, pecuária e silvicultura), que são historicamente responsáveis pela maior parte da conversão de ecossistemas nativos no país e na América do Sul. O Brasil criou várias políticas inovadoras para promover a sustentabilidade desses setores. Contudo, várias dessas políticas precisam ser de fato implementadas para gerar resultados tangíveis. O sucesso dessas políticas ainda é variável até aqui. Enquanto a conversão de habitats devida à expansão da produção rural, bem como o volume do comércio ilegal de madeira, tenham reduzido significativamente, os números absolutos de hectares de ecossistemas nativos convertidos em agricultura, pastagem ou silvicultura ainda é elevado, especialmente no Cerrado e na Amazônia. Além disso, o número de espécies ameaçadas por exploração ilegal de madeira ou para outros fins também é alto, particularmente na Amazônia e na Mata Atlântica.

Abstract Target 6 of the Global Strategy for Plant Conservation of the United Nations Convention on Biological Diversity states that by 2020 at least 75% of production lands in each sector will be managed sustainably, consistent with the conservation of plant diversity. Target 11 stipulates that by 2020 no species of the wild flora will be threatened by international trade. Both targets, therefore, are related to production, consumption and trade, which must be sustainable if the targets are to be achieved. Here we examine Brazil's progress in achieving these two targets. We focus on the three economic sectors of agriculture, cattle raising and forestry, which are historically responsible for most of the native-ecosystem conversion in the country and in South America. Brazil has set a number of innovative policies for moving these sectors towards a sustainable path. However, the country needs to put these policies into action to generate tangible results. The results of all efforts so far are mixed. Whereas ecosystem conversion due to the expansion of rural production and the volume of illegal international logging trade have been reduced significantly, the absolute number of hectares of native ecosystems converted into cropland, pastureland or planted forests remains high, especially in Amazonia and the Cerrado. In addition, the number of species threatened by illegal timber exploration remains high mainly in Amazonia and the Atlantic forest.

Abstract Invasive aspergillosis is a common fungal infection in immunocompromised individuals. Some studies have shown that toll-like receptor and dectin-1 genetic polymorphisms may alter signaling pathways, thus increasing an individual’s susceptibility to invasive aspergillosis. We investigated the pertinent literature to determine whether polymorphisms in the genes encoding toll-like receptors and dectin-1 increase the susceptibility to invasive aspergillosis. This study systematically reviewed the literature using the databases PubMed/PMC, Scopus, and Web of Science using the keywords invasive aspergillosis, polymorphism, Toll-like, and Dectin-1. From the initial search, 415 studies were found and according to our inclusion and exclusion criteria, eight studies were selected. Several studies described single-nucleotide polymorphisms (SNPs) that are associated with a greater susceptibility to invasive aspergillosis. These SNPs were found in the genes that encode toll-like receptors 1, 3, 4, and 5 and the gene that encodes dectin-1; upon activation, both cellular receptors initiate a signaling cascade that can result in the production of cytokines and chemokines. Thus, our literature review uncovered a significant association between polymorphisms in the genes that encode toll-like receptors and dectin-1 and invasive aspergillosis. More studies should be performed to better understand the relationship between toll-like receptor and dectin-1 genetic polymorphisms and invasive aspergillosis susceptibility.

Resumo O objetivo deste trabalho foi avaliar as características florais e físico-químicas do fruto de plantas da cultivar BRS Pérola do Cerrado de maracujazeiro silvestre (Passiflora setacea D.C.), bem como sua relação com os fatores climáticos locais. Foram avaliados o pico de florescimento; o tempo em dias do aparecimento floral até à antese e, em seguida, até à colheita dos frutos; a morfometria floral; os horários de abertura e de fechamento das flores; a ocorrência de autopolinização natural; de geitonogamia e de incompatibilidade floral; a característica físico-química dos frutos e a relação com as variáveis climáticas. Nas condições deste estudo, foi observado que o pico de florescimento ocorreu no mês de novembro e que o horário de abertura das flores variou de 19 horas e 21 minutos a 20 horas e 40 minutos ao longo do ano, provavelmente influenciado pela radiação solar diária; enquanto o horário de fechamento das flores ocorreu entre 6 e 8 horas. As flores, após seu fechamento, não apresentaram recorrência de abertura floral. As flores da espécie Passiflora setacea cv. BRS Pérola do Cerrado são autoincompatíveis e não possibilitam a geitonogamia, e confirma-se, portanto, para que haja formação de frutos, a necessidade de polinização cruzada. Quanto ao pegamento de frutos nos diferentes métodos de polinização, as taxas foram de 34,6% quando foram feitas de forma artificial e de 53,5% quando houve polinização natural. Os frutos apresentaram, em média, diâmetro longitudinal de 4,9 cm, diâmetro transversal de 4,6 cm e massa fresca de 55 g, volume de suco de 15,7 mL por fruto, 13,31º Brix e acidez total titulável de 1,7 g/100g ác. cítrico.

Abstract This work aimed to evaluate the floral and physicochemical characteristics of passion fruits BRS Pérola do Cerrado cultivar (Passiflora setacea D.C.), as well as its relationship with local climatic factors. Peak flowering, time in days of floral appearance until anthesis and until fruits harvest, floral morphometry, time of flower opening and closing, occurrence of natural self-pollination, geitonogamy and floral incompatibility, physicochemical characteristics of fruits and relationship with climatic variables were evaluated. Under the conditions of this study, it was observed that the flowering peak occurred in November and the time of flower opening ranged from 7:21 pm to 8:40 pm throughout the year, probably influenced by daily solar radiation; while the time of flower closing occurred between 6:00 am and 8:00 pm. After closing, flowers showed no recurrence of floral opening. Flowers of Passiflora setacea species BRS Pérola do Cerrado cultivar are self-incompatible and do not allow geitonogamy. Therefore, for fruit formation, cross-pollination is necessary. Regarding fruit setting in the different pollination methods, rates were 34.6% when artificially made and 53.5% in case of natural pollination. Fruits had, on average, longitudinal diameter of 4.9 cm, cross-sectional diameter of 46 mm and fresh mass of 55 g, juice volume of 15.7 ml per fruit, 13.31 ° Brix and total titratable acidity of 1.7 g / 100g ac. citric.

RESUMO O presente estudo objetivou avaliar o efeito da salinidade da água de irrigação no crescimento inicial de plantas de Tectona grandis. O trabalho foi conduzido em casa de vegetação com interceptação de 100% da radiação solar na Universidade Estadual de Goiás, Campus de Ipameri, Brasil. As sementes de Tectona grandis foram semeadas em vasos de oito litros contendo uma mistura de solo, areia e esterco na proporção de 3:1:0,5, respectivamente. Aos 100 dias após a germinação, as plantas foram irrigadas diariamente com água de diferentes condutividades elétricas (0; 2; 4; 6 e 8 dS m-1) durante 30 dias e, em seguida, submetidas às analises. Para se manterem vivas, as plantas de Tectona grandis reduziram a perda de água por transpiração através de um eficiente controle estomático. As plantas de Tectona grandis na fase inicial de desenvolvimento apresentam elevada sensibilidade ao estresse salino, inclusive com significativa redução do crescimento vegetativo.

ABSTRACT The objective of the present study was to evaluate the effect of the irrigation water salinity on the initial growth of Tectona grandis plants. The work was carried out in a greenhouse with 100% solar radiation interception at Goiás State University, Ipameri Campus, Brazil. The Tectona grandis seeds were sown in eight-liter pots containing a mixture of soil, sand and manure at ratio 3:1:0.5, respectively. At 100 days after germination, the plants were irrigated daily with water of different electrical conductivity (0, 2, 4, 6, and 8 dS m-1) for 30 days and then subjected to analysis Tectona grandis to stay alive and reduced water loss by transpiration through efficient stomatal control. Tectona grandis plants in the early stages of development are highly sensitive to salinity stress, significantly slowing down vegetative growth.

ABSTRACT INTRODUCTION: Invasive fungal infections (IFIs) are an important complication in immunocompromised individuals, particularly neutropenic patients with hematological malignancies. In this study, we aimed to verify the epidemiology and diagnosis of IFIs in patients with hematologic problems at a tertiary hospital in Goiânia-GO, Brazil. METHODS: Data from 117 patients, involving 19 cases of IFIs, were collected. The collected data included diagnosis methods, demographics, clinical characteristics, and in vitro susceptibility to different antifungal agents. Among the 19 cases, 12 were classified as proven IFI and 7 as probable invasive aspergillosis with detection of galactomannan in blood and presence of lung infiltrates in radiographic images. Logistic regression analysis showed that the proven and probable IFIs were associated with increased risk of death. Statistical analysis demonstrated that age, sex, and underlying disease were not independently associated with risk of death in IFI patients. RESULTS: Most bloodstream isolates of Candida spp. exhibited low minimum inhibitory concentrations (MICs) to all antifungal agents tested. Voriconazole and amphotericin had the lowest MICs for Aspergillus spp. and Fusarium spp., but Fusarium spp. showed the least susceptibility to all antifungals tested. Amphotericin B, fluconazole, and itraconazole were found to be inactive in vitro against Acremonium kiliense; but this fungus was sensitive to voriconazole. CONCLUSIONS: Considering the high number of IFI cases, with crude mortality rate of 6%, we could conclude that IFIs remain a common infection in patients with hematological malignancies and underdiagnosed ante mortem. Thus, IFIs should be monitored closely.

AbstractINTRODUCTION:Candida parapsilosis is a common yeast species found in cases of onychomycosis and candidemia associated with infected intravascular devices. In this study, we differentiated Candida parapsilosis sensu stricto, Candida orthopsilosis , and Candida metapsilosis from a culture collection containing blood and subungual scraping samples. Furthermore, we assessed the in vitro antifungal susceptibility of these species to fluconazole, itraconazole, voriconazole, posaconazole, amphotericin B, and caspofungin.METHODS:Differentiation of C. parapsilosis complex species was performed by amplification of the secondary alcohol dehydrogenase (SADH) gene and digestion by the restriction enzyme Ban I. All isolates were evaluated for the determination of minimal inhibitory concentrations using Etest, a method for antifungal susceptibility testing.RESULTS:Among the 87 isolates, 78 (89.7%) were identified as C. parapsilosis sensu stricto , five (5.7%) were identified as C. orthopsilosis , and four (4.6%) were identified as C. metapsilosis . Analysis of antifungal susceptibility showed that C. parapsilosis sensu strictoisolates were less susceptible to amphotericin B and itraconazole. One C. parapsilosis sensu stricto isolate was resistant to amphotericin B and itraconazole. Moreover, 10.2% of C. parapsilosis sensu stricto isolates were resistant to caspofungin. Two C. parapsilosis sensu strictoisolates and one C. metapsilosis isolate were susceptible to fluconazole in a dose-dependent manner.CONCLUSIONS:We reported the first molecular identification of C. parapsilosiscomplex species in State of Goiás, Brazil. Additionally, we showed that although the three species exhibited differences in antifungal susceptibility profiles, the primary susceptibility of this species was to caspofungin.

IntroductionThis is the first study to examine the in vitrosusceptibility and the expression of virulence factors in Candida species in the presence of Pimenta pseudocaryophyllus (Gomes) L.R. Landrum (Myrtaceae), a Brazilian plant known as paucravo. Additionally, the mechanisms of action of the crude ethanol extract and the ethyl acetate and aqueous fractions of this plant were investigated.MethodsThe in vitro susceptibility of Candida was tested using the broth microdilution method, whereas an XTT reduction assay was used for biofilms. Adherence was determined by counting the number of yeast cells that adhered to 100 oral epithelial cells, and hyphal formation was verified in the hyphal induction medium M199. Flow cytometry with propidium iodide and FUN-1 was performed to assess the mechanism of action.ResultsThe results revealed that the crude ethanol extract and the ethyl acetate and aqueous fractions of P. pseudocaryophyllusinhibited the growth of Candida isolates at a minimal inhibitory concentration (MIC) ranging from 64 to 256µg/mL, whereas the 50% sessile minimal inhibitory concentration (SMIC50) ranged from 512 to >1,024µg/mL. Adherence and hyphal formation were significantly reduced in the presence of the crude ethanol extract and both fractions. Although cell membrane injury was detected, the predominant mechanism of action appeared to be the alteration of yeast metabolism, as demonstrated by flow cytometry.ConclusionsOur results indicated that antifungal activity reduced the expression of virulence factors in yeast via the alteration of yeast metabolism, suggesting that the crude extract of P. pseudocaryophyllus and its fractions may contain novel antifungal agents.

INTRODUÇÃO: Candida albicans é responsável por infecções superficiais ou sistêmicas conhecidas como candidíase, encontrada em tecidos infectados na forma de leveduras brotantes unicelulares, hifas ou pseudohifas. Neste estudo, os efeitos de agentes antifúngicos como o fluconazol e o itraconazol sobre a formação de hifas e caracterização genotípica de isolados de C. albicans suscetíveis ou resistentes foram investigados. MÉTODOS: A produção de hifas de cinco isolados de C. albicans, sob a ação de antifúngicos foi investigada pelo cultivo da levedura em meios de crescimento e de indução de hifas. A caracterização genotípica foi realizada para 13 isolados de C. albicans pelo método de RAPD-PCR. RESULTADOS: A análise do dimorfismo mostrou que a formação de hifas foi maior nos isolados resistentes do que nos suscetíveis aos antifúngicos. O método de RAPD-PCR identificou a formação de dois diferentes grupos. No grupo A, foram agrupados quatro isolados resistentes e dois suscetíveis e no grupo B um resistente e seis suscetíveis. CONCLUSÕES: Considerando que a formação hifal foi maior em isolados resistentes na presença de azólicos, concluimos que a produção hifal está muito relacionada a suscetibilidade a estes fámacos. Estes antifúngicos podem alterar a morfologia de C. albicans em dependência da sua suscetibilidade. No método de RAPD-PCR, o encontro da maioria dos isolados resistentes classificados como pertencentes ao grupo A e suscetíveis ao grupo B demonstrou que este método apresentou um padrão semelhante entre os dois grupos, sugerindo que por este método pode ser detectado uma estreita correlação entre genótipos e amostras resistentes ao fluconazol.

INTRODUCTION: Candida albicans is responsible for superficial or systemic infections known as candidiasis, which may be found in infected tissue as unicellular budding yeasts, hyphae, or pseudohyphae. In this study, the effects of both fluconazole and itraconazole antifungal agents on the hyphal formation and genotypic characterization of C. albicans isolates classified as either susceptible or resistant were investigated. METHODS: The hyphal production of five C. albicans isolates under the action of antifungal agents was investigated by culturing yeast on growth medium and on hyphal induction medium. The genotypic characterization was carried out for 13 isolates of C. albicans using the random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) method. RESULTS: The dimorphism analysis showed that the hyphal formation was higher in resistant than in the susceptible isolates to both azoles. The RAPD-PCR method identified the formation of two different groups. In group A, four resistant and two susceptible isolates were clustered, and in group B, one resistant and six susceptible isolates were clustered. CONCLUSIONS: Considering that hyphal formation was higher in resistant isolates in the presence of azole drugs, we confirmed that the hyphal production is closely related to susceptibility to azoles. These drugs may affect the morphogenesis of C. albicans depending on their susceptibility to these drugs. In relation to RAPD-PCR, most resistant isolates classified in group A and susceptible isolates in group B demonstrated that this method presented a similar standard between the two groups, suggesting that by this technique, a strong correlation between genotypes and fluconazole-resistant samples may be found.

O poli-(cloreto de vinila) (PVC) necessita da adição de plastificantes, que são aditivos que conferem flexibilidade e maleabilidade para a sua transformação em filme flexível. Os mais utilizados são o adipato de di-(2-etil-hexila) (DEHA) e o ftalato de di-(2-etil-hexila) (DEHP). Efeitos tóxicos do DEHP foram observados por vários autores. Em virtude dos possíveis efeitos toxicológicos dos ftalatos, esses estão sendo substituídos por substâncias alternativas em produtos flexíveis de PVC. O DEHA é um substituto dos ftalatos amplamente utilizado como plastificante em filmes de PVC para materiais que envolvam alimentos. Alguns autores demonstraram que a exposição ao DEHA também causa toxicidade. Realizou-se um estudo seccional para identificar os alimentos gordurosos com possibilidades de contaminação por DEHA e DEHP. Foram determinados 18 alimentos diferentes, com no mínimo 3% (m/m) de gordura e com a possibilidade de acondicionamento em filme de PVC. Esse estudo sugeriu que todos os alimentos estavam passíveis de contaminações por DEHA e DEHP naquelas condições, na ordem de consumo decrescente de 96% a 22% na amostra de conveniência. Novas orientações com relação aos limites estabelecidos pela legislação brasileira de DEHA e DEHP, como aditivos em filmes de PVC para acondicionar alimentos gordurosos, continuam pertinentes para assegurar a saúde humana.

Poly-(vinyl chloride) (PVC) requires the addition of plasticizers - additives that give flexibility and malleability for its processing into flexible film. The most used ones are: di-(2-ethylhexyl) adipate (DEHA) and di-(2-ethylhexyl) phthalate (DEHP). Toxic effects of DEHP have been observed by several authors. Phthalates are being replaced by alternative substances in PVC flexible products, because of their possible toxicological effects. DEHA is a substitute for phthalates widely used as a plasticizer in PVC materials for involving food. Some authors have shown that the exposure to DEHA also induces toxicity. A cross-sectional study was performed to identify which fatty foods carry the possibility of contamination by DEHP and DEHA. Eighteen different foods with at least 3% (m/m) fat and the possibility of being wrapped in plastic film were determined. This study suggested that all foods were subject to contamination by DEHP and DEHA in those conditions - in decreasing consumption order of 96 to 22% in the convenience sample. New guidelines on the limits of DEHA and DEHP established by the Brazilian legislation, as additives in PVC film for packaging fatty food, are still relevant to ensure human health.

Candida species are of common occurrence in the buccal cavity and these yeasts are present in about 50% of healthy individuals. This percentage can change depending on the studied population. The infectious processes caused by Candidavary of benign clinical pictures, to serious and fatal pictures as the invasive infections and disseminated. In this study it was evaluated the colonization of yeasts of the Candida genus on 312 saliva sample of the hospital workers from "Hospital das Clínicas da Universidade Federal de Goiás" in the city of Goiania-Goiás/Brazil,during the period from July to December of 2007. Candidaspecies were identified by production of germ-tube, chlamydospore formation, assimilation sugar tests and culture on CHROMagar®Candida. The hospital workers analyzed presented colonization of the saliva by yeasts of the Candidagenus in 61.9% from samples studied, being isolated C. albicans (58.5%), C. parapsilosis (24.4%), C. krusei (8.3%) and C. famata (3.6%). The publication of these results can serve as an aid for the prevention and control of oral candidiasis in the workers of the area of health that live in contact with individuals susceptible to infections.

Especies de Candida son de ocurrencia común en la cavidad bucal y estas levaduras están presentes en cerca del 50% de individuos sanos. La frecuencia varía, dependiendo de las personas investigadas. Los procesos infecciosos causados por Candida varían de cuadros clínicos benignos, a los cuadros serios y fatales como las infecciones invasivas y diseminadas. En este estudio ha sido evaluado la colonización de las especies de Candidaen la saliva de los obreros del Hospital das Clínicas de la Universidad Federal de Goiás en Goiânia, Brasil, entre julio y diciembre de 2007. El trabajo se llevó a cabo con 312 muestras de saliva. Las especies de Candidaaisladas de la saliva fueron identificadas a través de la formación de tubo germinal y de clamidoconídio, asimilación de carbohidratos y cultivo en CHROMagar® Candida. En nuestro estudio, 61.9% de los trabajadores analizados del hospital presentaron colonización de la saliva por las levaduras del género Candida, estar aislado C. albicans (58.5%), C. parapsilosis (24,4%), C. krusei(8,3%) y C. famata(3,6%). La divulgación de estos resultados puede servir como una ayuda para la prevención y control de candidíase bucal en los trabajadores del área de salud que viven en contacto constante con individuos susceptibles a las infecciones.

As espécies de Candida são de ocorrência comum na cavidade bucal sendo que estas leveduras estão presentes em cerca de 50% de indivíduos saudáveis, podendo este porcentual variar dependendo da população estudada. Os processos infecciosos causados por Candida variam de quadros clínicos benignos, a quadros graves e fatais como as infecções invasivas e disseminadas. Neste estudo foi avaliada a colonização de leveduras do gênero Candida em 312 amostras de saliva de profissionais do Hospital das Clínicas da Universidade Federal de Goiás, na cidade de Goiânia, Goiás, Brasil, durante o período de julho a dezembro de 2007. As espécies de Candida isoladas da saliva foram identificadas através da produção de tubo germinativo e de clamidoconídios, assimilação de carboidratos e cultivo em meio CHROMagar® Candida. Os profissionais estudados mostraram colonização por leveduras do gênero Candida em 61,9% das amostras analisadas, sendo isolados C. albicans (58,5%), C. parapsilosis (24,4%), C. krusei (8,3%) e C. famata (3,6%). A divulgação destes resultados pode servir como um auxílio para a prevenção e controle de candidíase bucal nos trabalhadores da área de saúde que vivem em contato constante com indivíduos altamente suscetíveis a infecções.

Baseados na Constituição de 1988 e no Estatuto da Criança e do Adolescente, de 1990, o Centro de Defesa dos Direitos da Criança e do Adolescente de Interlagos (CEDECA Interlagos) traz um relato de experiência de uma metodologia alternativa de acompanhamento de adolescentes inseridos em medidas socioeducativas em meio aberto na região da Capela do Socorro e Parelheiros. Essa proposta utiliza o futebol como meio que possibilita ao adolescente refletir sobre sua realidade e suas práticas cotidianas, reconhecendo suas possibilidades de se desenvolver como sujeito de direito e de se tornar protagonista no que diz respeito às ações que busquem sua promoção social e a construção e o exercício da cidadania ativa. É possível observar que, com esse tipo de linguagem, mais próximo do desejo desses jovens, os mesmos atribuem um novo sentido ao acompanhamento a que foram submetidos. Na lógica socioeducativa, procuram superar obstáculos no sentido de buscar cada vez mais seu protagonismo, sua autoria, para reafirmar o que o ato infracional revelou, que é a busca por ser sujeito.

Based on the Brazilian Constitution (1988) and on the Child and Adolescente Statute (ECA/1990, Brazilian Statute for the Protection of Children and Adolescents), the Defense Center of the Child and Adolescent’s Rights (CEDECA Interlagos) has developed and applied an alternative methodology for socioeducational measures for those who work with young offenders on parole. This report concerns a particular project for the adolescents who live in Capela do Socorro and Parelheiros - districts in the city of São Paulo with several social problems that lead to high levels of social vulnerability. The project has used soccer as a means of reflection on the youngsters’ reality and everyday lives. The process focuses on the opportunity they are given to develop self-consciousness as citizens who have rights. The aim of the project, therefore, is the promotion of their own social well-being, so that they may become active citizens. It is possible to see that this kind of language, closer to the desire of these adolescents, gives them a new meaning to the monitoring they have undergone. In a socioeducative point of view, they seek to overcome the obstacles in order to find out what is their increasingly prominet role, and so they reaffirm what the act of infraction pointed out, that is, their search to be subjects of their rights.

Basados en la Constitución de 1988 y en el Estatuto del Niño y del Adolescente, de 1990, el Centro de Defensa de los Derechos del Niño y del Adolescente de Interlagos (CEDECA Interlagos) trae un relato de experiencia de una metodología alternativa de acompañamiento de adolescentes inseridos en medidas socioeducativas en medio abierto en la región de Capela do Socorro y Parelheiros. Esa propuesta utiliza el fútbol como medio que posibilita al adolescente reflejar sobre su realidad y sus prácticas cotidianas, reconociendo sus posibilidades de desarrollarse como sujeto de derecho y de convertirse en protagonista en lo que se refiere a las acciones que busquen su promoción social y la construcción y el ejercicio de la ciudadanía activa. Es posible observar que, con ese tipo de lenguaje, más próximo del deseo de estos jóvenes, los mismos atribuyen un nuevo sentido al acompañamiento a que fueron sometidos. En la lógica socioeducativa, buscan superar obstáculos en el sentido de buscar cada vez más su protagonismo, su autoría, para reafirmar lo que el acto de la infracción reveló, que es la búsqueda por ser sujeto.