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Abstract Brazil is a large producer of dairy products, with an important role of milk in the country's economy beyond the nutritional aspects. In turn, the dairy industry is associated with environmental impacts, such as water and energy consumption, waste generation, liquid effluents, and atmospheric emissions. Life Cycle Assessment (LCA) is an environmental management tool used to measure the environmental impacts of goods, services, and products. This study used the LCA to assess the impacts resulting from the production of Minas Frescal and cured Minas cheese in an artisanal production facility in Casimiro de Abreu, Rio de Janeiro, Brazil. LCA results showed that the most significant environmental impacts were associated with the dairy farm under study, which is a source of greenhouse gases (GHG) emissions from livestock, particularly methane (CH4), produced through enteric fermentation and manure decomposition, mainly contributing for the impact categories of climate change (31.56%) and human toxicity with carcinogenic effects (35.46%). The cured Minas cheese presented higher impacts when compared to Minas Frescal cheese due to the larger volume of milk used in the manufacturing process. Thus, the present study suggested mitigation measures to lower the environmental impacts based on adjustments in animal feed to reduce atmospheric emissions.

https://doi.org/10.1590/fst.109522

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Abstract: En | Text: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

A scoping review about LGBTQIAP+ people in oral health research
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SILVA, Eliane Maria Mascarenhas da

; FÉLIX, Thallys Rodrigues

; BÖNECKER, Marcelo

; ZINA, Lívia Guimarães

; DRUMMOND, Andreia Maria Araújo

; MATTOS, Flávio Freitas

Brazilian Oral Research

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2023, Volume 37 elocation e125

Abstract: En | Text: En | PDF: En

Abstract Oral health personnel must acknowledge the health needs of sexual and gender minorities. They should consult scientific literature to deepen their knowledge about sexuality, gender identity, general and oral health status, and treatment disparities among LGBTQIA+ people. The aim of this scoping review was to portray the development and current stage of internationally indexed literature approaching the oral health of this population. In this study, the search strategy used consisted of combinations of subject descriptors (MeSH terms), in two concept blocks: LGBTQIAP+ people and oral health. Global literature was searched through Medline (PUBMED), Web of Science, Embase, Lilacs, and Scopus electronic databases, with no language or date restrictions. Records were selected and evaluated by two independent reviewers, under the supervision of three senior reviewers and the inclusion criteria resulted in 189 eligible papers. Since the first study was published in 1974, numbers increased over the decades, reaching 67 (35.4%) in 2010-2019. The most frequently studied populations were North American (42.9%) and European (19.0%) and the most frequent language of publication was English (99.0%). There were 38 open access papers (20.1%). Medical (57.7%) and dental journals (20.1%) predominated. Cross-sectional studies were found more frequently (65.1%), followed by the cohort type (11.1%). Oral manifestation of STI (58.7%) was the topic most frequently addressed. The search for literature approaching the oral health of LGBTQIAP+ people showed evidence of the need to encourage research reported in papers made easily available, with more robust scientific evidence, and on a broader scope of topics, including oral health needs and treatment, and planning of oral health services.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0125

Effect of entomopathogenic fungi on the control of the coffee berry borer in the laboratory
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Ferreira, Juliana Silva

; Andaló, Vanessa

; Fuga, Cícero Augusto Guimarães

; Sousa, Thaigoru Soares de

; Soares, Carlos Marcelo Silveira

Arquivos do Instituto Biológico

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2023, Volume 90 elocation e00112023

Abstract: En | Text: En | PDF: En

ABSTRACT Among the management and control tactics of the coffee berry borer Hypothenemus hampei (Ferrari), there is the use of entomopathogenic fungi. Due to the importance of prospecting isolates of entomopathogenic fungi for the control of the coffee berry borer, the objective of this study was to evaluate the efficiency of 26 isolates of entomopathogenic fungi in the control of this insect pest in the laboratory. The coffee berry borers were immersed in a solution adjusted to the concentration of 1 to 3 × 108 conidia/mL of each isolate and the control treatment (sterilized water). After seven days total mortality and confirmed mortality were evaluated. The isolates that caused the highest mortality and two commercial isolates were selected for evaluation of lethal concentration (LC50 and LC90) and lethal time (LT50 and LT90). Coffee berry borers were treated at different conidia concentrations for lethal concentration to assess total and confirmed mortality. For a lethal time, the coffee berry borers were treated at the concentration of 108 conidia/mL of the selected isolates, and, after two days and every 24 hours until the eighth day, the number of dead individuals was verified. Among the 26 isolates evaluated, 24 presented mortality higher than the control treatment, and three presented mortality higher than 85%. In the LC50 and LC90 assays, the IBCB 353 and IBCB 364 isolates were more lethal to H. hampei. In the LT50 and LT90 assays, the IBCB 66 and IBCB 353 isolates caused lethality in a shorter time.

https://doi.org/10.1590/1808-1657000112023

Knowledge of Dentists about Hypomineralization Enamel Defects: A Cross-Sectional Study
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Costa, Alice Pinheiro

; Silva, Fernanda Mafei Felix da

; Vieira, Fernanda Gabriela de Fátima

; Primo, Laura Guimarães

; Costa, Marcelo de Castro

Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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2023, Volume 23 elocation e220059

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To evaluate a group of Brazilian dentists on their knowledge of Molar Incisor Hypomineralization (MIH) and Hypomineralized Second Primary Molars (HSPM) related to clinical aspects, consequences, and diagnostic criteria. Material and Methods: In this cross-sectional, the participants were invited by e-mail and Whatsapp® to answer a questionnaire about their knowledge of hypomineralization enamel defects (MIH/HSPM) on the Google Forms® platform. The questionnaire comprised eight questions about personal data and multiple-choice questions about their knowledge concerning clinical aspects, diagnostic criteria of MIH/HSPM and differential diagnosis through clinical images. Chi-square test was applied with the significance level set at 5%. Results: Most participants (n = 492; 91.1%) reported having knowledge about MIH/HSPM. The general dentists gave more incorrect answers (n = 40; 65.6 %;) about dental tissues affected by MIH/HSPM. Overall, 83.3% of the dentists gave the correct answer to which dentitions are associated with this condition. In addition, most dentists presented knowledge about the consequences related to possible fractures (n= 487; 90.2%) and about an increased risk of caries (n= 479; 88.9%) in the affected teeth. Regarding the differential diagnosis performed through clinical images, most participants gave incorrect answers (p≤0.001). Conclusion: The participants presented knowledge about the dentition associated with this condition and possible consequences related to the teeth affected by MIH/HSPM; however, they showed difficulties concerning clinical diagnostic criteria.

https://doi.org/10.1590/pboci.2023.047

Pediatric peritoneal dialysis in Brazil: a discussion about sustainability. A document by the Brazilian Society of Nephrology, the Brazilian Society of Pediatrics, the Brazilian Association of Organ Transplantation, and the Brazilian Association of Dialysis and Transplant Centers
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Palma, Lilian Monteiro Pereira

; Penido, Maria Goretti Moreira Guimarães

; Bresolin, Nilzete Liberato

; Tavares, Marcelo de Sousa

; Sylvestre, Lucimary

; Andrade, Olberes Vitor Braga de

; Bernardes, Rejane de Paula

; Bandeira, Maria de Fátima Santos

; Garcia, Clotilde Druck

; Koch, Vera Hermina Kalika

; Belangero, Vera Maria Santoro

; Uhlmann, Anelise

; Soeiro, Emília Maria Dantas

; Kaufman, Arnauld

; Andrade, Maria Cristina de

; Silva, Roxana de Almeida Roque Fontes

; Calice-Silva, Viviani

; Vieira, Marcos Alexandre

; Merege Neto, Osvaldo Vieira

Brazilian Journal of Nephrology

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dec 2022, Volume 44 N. 4 Pages 579 - 584

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Introdução: A diálise peritoneal (DP) é importante para a pediatria. Este estudo mostrou dados de centros brasileiros que utilizam DP pediátrica. Método: Estudo transversal, observacional, descritivo com questionário eletrônico. Incluiu-se pacientes de 0-18 anos em DP cadastrados nos bancos de dados dos diversos centros. Questionário preenchido anonimamente, sem dados de identificação. Foi adotada metodologia quantitativa. Resultados: 212 pacientes estão em DP no Brasil (agosto, 2021). 80% têm menos de 12 anos de idade. A maioria realiza DP automatizada e 74% são dependentes do Sistema Único de Saúde. Em 25% dos centros faltou material de DP e em 51% os pacientes pediátricos foram convertidos de DP para HD. Conclusão: A maioria dos pacientes tinha menos de 12 anos e era dependente do SUS. A escassez de insumos aconteceu em 25% dos centros. Esses dados apontam para o problema da sustentabilidade de DP, única alternativa de TRS em crianças muito pequenas.

Resumo Introdução: A diálise peritoneal (DP) é importante para a pediatria. Este estudo mostrou dados de centros brasileiros que utilizam DP pediátrica. Método: Estudo transversal, observacional, descritivo com questionário eletrônico. Incluiu-se pacientes de 0-18 anos em DP cadastrados nos bancos de dados dos diversos centros. Questionário preenchido anonimamente, sem dados de identificação. Foi adotada metodologia quantitativa. Resultados: 212 pacientes estão em DP no Brasil (agosto, 2021). 80% têm menos de 12 anos de idade. A maioria realiza DP automatizada e 74% são dependentes do Sistema Único de Saúde. Em 25% dos centros faltou material de DP e em 51% os pacientes pediátricos foram convertidos de DP para HD. Conclusão: A maioria dos pacientes tinha menos de 12 anos e era dependente do SUS. A escassez de insumos aconteceu em 25% dos centros. Esses dados apontam para o problema da sustentabilidade de DP, única alternativa de TRS em crianças muito pequenas.

https://doi.org/10.1590/2175-8239-jbn-2021-0245

Long-term measurements of aerosol optical properties and radiative forcing (2011-2017) over Central Amazonia
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Palácios, Rafael da Silva

; Artaxo, Paulo

; Cirino, Glauber Guimarães

; Nakale, Valeria

; Morais, Fernando Gonçalves de

; Rothmund, Lucas Douglas

; Biudes, Marcelo Sacardi

; Machado, Nadja Gomes

; Curado, Leone Francisco Amorim

; Marques, João Basso

; Nogueira, José de Souza

Atmósfera

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2022, Volume 35 N. 1 Pages 143 - 163

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The Amazon region is one of the most pristine continental areas whose concentrations of atmospheric trace gases and aerosol particles are very low, mainly in the wet season. This study provides observational results of aerosol optical and radiative characteristics in situ as well as atmospheric columnar at a pristine forest in Central Amazonia. Spectral variation of the aerosol properties (aerosol optical depth [AOD], single scattering albedo [SSA], and asymmetry parameter [AP]) was evaluated using the AErosol RObotic NETwork (AERONET) data. The SSA values under natural atmospheric column conditions (AERONET) were compared to the SSA values calculated with in situ measurements. The values of shortwave aerosol radiative forcing (SWARF) on top of the atmosphere (TOA) and the surface (SUR) were estimated using the SBDART model and were validated with the AERONET values with regression analysis. SWARF had a high correlation to TOA (0.97) and SUR (0.92), including dry and wet seasons. Monthly, seasonal and annual mean values of SWARFTOA and SWARFSUR were negative while SWARFATM values were positive. SWARFTOA was -9.18 ± 2.80 W m-2 and SWARFSUR was -20.77 ± 5.04 W m-2 in the dry season, inducing a heating rate (HR) of 0.37 ± 0.13 K.day-1. This study showed that, for a long series of measurements, the effects caused by aerosols on the radiative flux in the pristine forest of Central Amazonia were of the order of SWARFTOA of -3.66 ± 1.59 W m-2 and SWARFSUR of -11.86 ± 2.35 W m-2 during the wet season.

RESUMEN La región del Amazonas es una de las áreas continentales más impolutas, cuyas concentraciones de gases traza atmosféricos y partículas de aerosol son muy bajas, sobre todo en la estación húmeda. El presente estudio proporciona resultados observacionales in situ tanto de las características ópticas y radiativas como de la columna atmosférica de los aerosoles en un bosque virgen de la Amazonia Central. Se evaluó la variación espectral de las propiedades de los aerosoles (profundidad óptica de aerosoles [AOD, por sus siglas en inglés], albedo de dispersión simple [SSA] y parámetro de asimetría [AP]) utilizando para ello datos de la Red Robótica de Aerosoles (AERONET). Los valores de SSA en condiciones naturales de la columna atmosférica (obtenidos de AERONET) se compararon con valores de SSA obtenidos de mediciones in situ. Se estimaron los valores del forzamiento radiativo de onda corta (SWARF) en el techo de la atmósfera (TOA) y en la superficie (SUR) con datos del modelo SBDART y se validaron con valores de AERONET utilizando análisis de regresión. Los valores de SWARF tuvieron una alta correlación con los de TOA (0.97) y SUR (0.92), incluyendo las temporadas húmeda y seca. Los valores promedio mensuales, estacionales y anuales de SWARFTOA y SWARFSUR fueron negativos, en tanto que los de SWARFATM fueron positivos. Los valores de SWARFTOA fueron de -9.18 ± 2.80 W m-2 y los de SWARFSUR de -20.77 ± 5.04 W m-2 en la estación seca, induciendo una tasa de calentamiento (HR) de 0.37 ± 0.13 K día-1. El presente estudio muestra que, para series largas de medición, los efectos ocasionados por los aerosoles en el flujo radiativo en un bosque virgen de la Amazonia Central fueron del orden de -3.66 ± 1.59 W m-2 para SWARFTOA y de -11.86 ± 2.35 W m-2 para SWARFSUR durante la temporada húmeda.

https://doi.org/10.20937/atm.52892 11 downloads

Brazilian Thoracic Association Consensus on Sleep-disordered Breathing
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Duarte, Ricardo Luiz de Menezes

; Togeiro, Sonia Maria Guimarães Pereira

; Palombini, Luciana de Oliveira

; Rizzatti, Fabíola Paula Galhardo

; Fagondes, Simone Chaves

; Magalhães-da-Silveira, Flavio José

; Cabral, Marília Montenegro

; Genta, Pedro Rodrigues

; Lorenzi-Filho, Geraldo

; Clímaco, Danielle Cristina Silva

; Drager, Luciano Ferreira

; Codeço, Vitor Martins

; Viegas, Carlos Alberto de Assis

; Rabahi, Marcelo Fouad

Jornal Brasileiro de Pneumologia

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2022, Volume 48 N. 4 elocation e20220106

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O sono é essencial para o adequado funcionamento de todos os indivíduos. Os distúrbios respiratórios do sono ocorrem em todas as faixas etárias, constituindo motivo frequente de consulta médica. O objetivo deste consenso foi atualizar os conhecimentos sobre os principais distúrbios respiratórios do sono tanto na população adulta quanto na pediátrica, com ênfase na apneia obstrutiva do sono. A apneia obstrutiva do sono é uma doença extremamente prevalente, porém frequentemente subdiagnosticada. Associa-se frequentemente a uma série de comorbidades, notadamente cardiovasculares, metabólicas e neurocognitivas, que impactam significativamente na qualidade de vida e na mortalidade. Por conta disso, o Departamento de Distúrbios Respiratórios do Sono da Sociedade Brasileira de Pneumologia e Tisiologia reuniu 14 especialistas com reconhecida e comprovada experiência em distúrbios respiratórios do sono para a elaboração deste documento.

ABSTRACT Sleep is essential for the proper functioning of all individuals. Sleep-disordered breathing can occur at any age and is a common reason for medical visits. The objective of this consensus is to update knowledge about the main causes of sleep-disordered breathing in adult and pediatric populations, with an emphasis on obstructive sleep apnea. Obstructive sleep apnea is an extremely prevalent but often underdiagnosed disease. It is often accompanied by comorbidities, notably cardiovascular, metabolic, and neurocognitive disorders, which have a significant impact on quality of life and mortality rates. Therefore, to create this consensus, the Sleep-Disordered Breathing Department of the Brazilian Thoracic Association brought together 14 experts with recognized, proven experience in sleep-disordered breathing.

https://doi.org/10.36416/1806-3756/e20220106

10.

Ultrasonographic evaluation of cecal appendix diameter in pediatric population
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Queiroz, Marcos Roberto Gomes de

; Francisco Neto, Miguel José

; Rahal Junior, Antonio

; Jabour, Victor Arantes

; Andrade, Guilherme Neves Lourenço

; Silva, Paulo Savoia Dias da

; Garcia, Rodrigo Gobbo

; Pereira, Marcelo dos Santos

; Santos, Marina Ramos

; Luna, Pedro Andrade Alencar

; Sameshima, Yoshino Tamaki

; Gual, Fabiana

; Dutra, Marcelo Guimarães

; Germino, Beatriz Placca

; Alves, Isabella Ferreira

einstein (São Paulo)

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2022, Volume 20 elocation eAO6935

Abstract: En | Text: En | PDF: En

ABSTRACT Objective To stratify ultrasound samples in a pediatric population undergoing evaluation for acute appendicitis to examine the variability in cecal appendix diameter, in different age groups, and to determine whether there is a prevalent value for each age group. Methods A retrospective cross-sectional study with 196 children aged 0 to 15 years. Data were extracted from reports of ultrasound examinations carried out between 2008 and 2015. Children with sonographic diagnosis of appendicitis or other signs of periappendiceal inflammation were excluded. Results The evaluation of the anteroposterior measurement of the cecal appendix revealed a mean diameter of 4.14mm (standard deviation: 0.93mm; 95%CI: 3.86-4.14). Cecal appendix diameter did not differ significant between age groups. Conclusion Evaluation of the anteroposterior diameter of the cecal appendix in centimeters in a sample of 196 children aged 0 to15 years revealed a mean diameter of 4.14mm (standard deviation, 0.93mm. There were no significant differences in cecal appendix diameter following stratification by age. Results indicate a single value can be adopted for mean cecal appendix diameter in pediatric populations.

https://doi.org/10.31744/einstein_journal/2022ao6935

11.

AÇÃO PÚBLICA SOCIOAMBIENTAL EM QUESTÃO: desafios da cogestão de uma Resex Marinha na Amazônia brasileira
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Oliveira, Marcelo do Vale

; Ribeiro, Tânia Guimarães

; Teisserenc, Maria José da Silva Aquino

Caderno CRH

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2022, Volume 35 elocation e022030

Abstract: Pt En Fr | Text: Pt En Fr | PDF: Pt | PDF: En | PDF: Fr

O objeto em questão é a participação na construção de um Plano de Manejo, dispositivo exigido pela implementação de um instrumento de política pública ambiental como a Resex. A referência territorial envolve a Resex Marinha Caeté-Taperaçu, situada no município de Bragança, Estado do Pará. O objetivo é compreender como se coproduziu o Plano de Manejo, relacionando-o a um contexto de ambientalização e participação para demonstrar as relações entre os atores envolvidos, seus conhecimentos, práticas e interesses em confronto. A partir de uma abordagem sociológica da ação pública, traz-se uma perspectiva das políticas públicas onde o Estado tem sua centralidade contestada e onde a participação de diferentes atores nas discussões e gerenciamento de seu território, se não tem sido evidente, não deixou também de se constituir enquanto horizonte de governança a ser buscado em dinâmicas e mobilizações locais, expressas na capacidade dos atores e de sua atuação em ações coletivas.

The object in question is participation in the construction of a Management Plan, a device required by the implementation of environmental public political instrument such as Resex. The territorial reference involves the Caeté-Taperaçu Marine Resex, located in the municipality of Bragança, state of Pará. The objective is to understand how the Management Plan was co-produced, relating it to a context of environmentalization and participation, to demonstrate the relationships between the actors involved, their knowledge, practices and interests in confrontation. From a sociological approach to public action brings a perspective of public policies, where the state has its centrality challenged and where the participation of different actors in the discussions and management of its territory has not been evident, but also constitute as a horizon of governance to be sought in local dynamics and mobilizations, expressed in the capacity of the actors and their performance in collective actions.

L'objet en question est la participation à la construction d'un plan de gestion, un disposit if requis par la mise en œuvre d'un instrument de politique publique environnementale tel que Resex. La référence territoriale concerne le Résex marin Caeté-Taperaçu, situé dans la municipalité de Bragança, dans l’État de Pará. Dont l'object if est de comprendre comment le plan de gestion a été coproduit, en le reliant à un contexte d'environnement alisation et de participation, afin de démontrer les relations entre les acteurs impliqués, leurs connaissances, leurs pratiques et leurs intérêts en confrontation. L'approche sociologique de l'action publique donne une perspective des politiques publiques, où la centralité de l’État est contestée et où la participation de différents acteurs aux discussions et à la gestion de son territoire n'a pas été évidente, mais où constituer comme un horizon de gouvernance à rechercher dans les dynamiques et les mobilisations locales, se traduisant par la capacité des acteurs et leur performance dans les actions collectives.

https://doi.org/10.9771/ccrh.v35i0.34542

12.

Bee sting envenomation severe cases in Manaus, Brazilian Amazon: clinical characteristics and immune markers of case reports
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Mendonça-da-Silva, Iran

; Monteiro, Wuelton Marcelo

; Sachett, Jacqueline Almeida Gonçalves

; Barbosa, Endila Souza

; Cordeiro-dos-Santos, Marcelo

; Lacerda, Marcus Vinícius Guimarães

; Melo, Gisely Cardoso

; Costa, Allyson Guimarães

; Val, Fernando Fonseca Almeida

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e20200319

Abstract: En | Text: En | PDF: En

Abstract Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. We also describe clinical characteristics and immune markers. Both victims suffered from respiratory distress, renal failure, rhabdomyolysis, and shock. They required invasive mechanical ventilation, vasoactive drugs, and renal replacement therapy. Moreover, serum levels of chemokines, cytokines, and cell-free circulating nucleic acids demonstrated an intense inflammatory process. Massive envenoming produced systemic injury in the victims, with an uncontrolled inflammatory response, and a more significant chemotactic response in the fatal case.

https://doi.org/10.1590/0037-8682-0319-2021 717 downloads

13.

Brazilian recommendations for the use of nonsteroidal anti-inflammatory drugs in patients with axial spondyloarthritis
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Lage, Ricardo da Cruz

; Marques, Claudia Diniz Lopes

; Oliveira, Thauana Luiza

; Resende, Gustavo Gomes

; Kohem, Charles Lubianca

; Saad, Carla Gonçalves

; Ximenes, Antônio Carlos

; Gonçalves, Célio Roberto

; Bianchi, Washington Alves

; Meirelles, Eduardo de Souza

; Keiserman, Mauro Waldemar

; Chiereghin, Adriano

; Campanholo, Cristiano Barbosa

; Lyrio, André Marun

; Schainberg, Cláudia Goldenstein

; Pieruccetti, Lenise Brandao

; Yazbek, Michel Alexandre

; Palominos, Penelope Esther

; Goncalves, Rafaela Silva Guimarães

; Assad, Rodrigo Luppino

; Bonfiglioli, Rubens

; Lima, Sônia Maria Alvarenga Anti Loduca

; Carneiro, Sueli

; Azevedo, Valderílio Feijó

; Albuquerque, Cleandro Pires

; Bernardo, Wanderley Marques

; Sampaio-Barros, Percival Degrava

; Pinheiro, Marcelo de Medeiros

Advances in Rheumatology

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2021, Volume 61 elocation 4

Abstract: En | Text: En | PDF: En

Abstract Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA). However, the emergence of the immunobiologic agents brought up the discussion about the role of NSAIDs in the management of these patients. The objective of this guideline is to provide recommendations for the use of NSAIDs for the treatment of axSpA. A panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis of randomized clinical trials for 15 predefined questions. The Grading of Recommendations, Assessment, Development and Evaluation methodology to assess the quality of evidence and formulate recommendations were used, and at least 70% agreement of the voting panel was needed. Fourteen recommendations for the use of NSAIDs in the treatment of patients with axSpA were elaborated. The purpose of these recommendations is to support clinicians’ decision making, without taking out his/her autonomy when prescribing for an individual patient.

https://doi.org/10.1186/s42358-020-00160-6 505 downloads

14.

Severe tissue complications in patients of Bothrops snakebite at a tertiary health unit in the Brazilian Amazon: clinical characteristics and associated factors
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Silva, Flavio Souza

; Ibiapina, Hiochelson Najibe Santos

; Neves, Juliana Costa Ferreira

; Coelho, Kerolaine Fonseca

; Barbosa, Fabiane Bianca Albuquerque

; Lacerda, Marcus Vinicius Guimarães

; Sachett, Jacqueline Almeida Gonçalves

; Malheiro, Adriana

; Monteiro, Wuelton Marcelo

; Costa, Allyson Guimarães

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0374-2020

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION: Snakebites in the Brazilian Amazon are caused mostly by snakes from the Bothrops genus and envenomated patients may suffer from tissue complications. METHODS: This study aimed to identify risk factors for severe tissue complications (STC) in patients with Bothrops snakebite in the Amazonas state, Brazil. RESULTS: Snakebites that were classified as severe and affected female patients with comorbidities presented greater risks of developing STCs. In addition, hospitalizations of patients with STC exceeded 5 days. CONCLUSIONS: Clinical and epidemiological characteristics can prove essential for assessing the evolution of STC and clinical prognosis of patients with Bothrops snakebites.

https://doi.org/10.1590/0037-8682-0374-2020 564 downloads

15.

Brazilian Society of Rheumatology 2020 guidelines for psoriatic arthritis
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Carneiro, Sueli

; Palominos, Penelope Esther

; Anti, Sônia Maria Alvarenga

; Assad, Rodrigo Luppino

; Gonçalves, Rafaela Silva Guimarães

; Chiereghin, Adriano

; Lyrio, Andre Marun

; Ximenes, Antônio Carlos

; Saad, Carla Gonçalves

; Gonçalves, Célio Roberto

; Kohem, Charles Lubianca

; Marques, Cláudia Diniz Lopes

; Schainberg, Cláudia Goldenstein

; Meirelles, Eduardo de Souza

; Resende, Gustavo Gomes

; Pieruccetti, Lenise Brandao

; Keiserman, Mauro Waldemar

; Yazbek, Michel Alexandre

; Sampaio-Barros, Percival Degrava

; Lage, Ricardo da Cruz

; Bonfiglioli, Rubens

; Oliveira, Thauana Luíza

; Azevedo, Valderílio Feijó

; Bianchi, Washington Alves

; Bernardo, Wanderley Marques

; Simões, Ricardo dos Santos

; Pinheiro, Marcelo de Medeiros

; Campanholo, Cristiano Barbosa

Advances in Rheumatology

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2021, Volume 61 elocation 69

Abstract: En | Text: En | PDF: En

Abstract Psoriatic arthritis (PsA) is a chronic and systemic immune disease characterized by inflammation of peripheral and/ or axial joints and entheses in patients with psoriasis (PsO). Extra-articular and extracutaneous manifestations and numerous comorbidities can also be present. These recommendations replace the previous version published in May 2013. A systematic review of the literature retrieved 191 articles that were used to formulate 12 recommendations in response to 12 clinical questions, divided into 4 sections: diagnosis, non-pharmacological treatment, conventional drug therapy and biologic therapy. These guidelines provide evidence-based information on the clinical management for PsA patients. For each recommendation, the level of evidence (highest available), degree of strength (Oxford) and degree of expert agreement (interrater reliability) are reported.

https://doi.org/10.1186/s42358-021-00219-y

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