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ABSTRACT Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs.

https://doi.org/10.1590/0037-8682-0238-2022

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients
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Viana, Glautemberg de Almeida

; Costa, Mac Dionys Rodrigues da

; Silva, Mateus Edson da

; Silva, Victória da Costa

; Ali, Arif

; Siqueira, Erlânia Alves de

; Alves, Renata de Sousa

; Martins, Alice Maria Costa

; Menezes, Ramon Róseo Paula Pessoa Bezerra de

; Queiroz, Maria Goretti Rodrigues de

; Sampaio, Tiago Lima

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e23293

Abstract: En | Text: En | PDF: En

Abstract Changes in lipoprotein metabolism are among the main causes of hemodynamic impairment in renal function. COVID-19 is an multisystemic inflammatory disease, aggravating this situation. This cross-sectional study investigated the relationship of serum lipoprotein profile with inflammatory parameters and renal function in 95 COVID-19 outpatients in comparison with 173 with flu-like symptoms. Serum samples were collected for the determination of total cholesterol and fractions, apolipoproteins (Apo A-I and Apo B), urea (sUr) and creatinine (sCr). The glomerular filtration rate (eGFR) was calculated. Neutrophil/lymphocyte (NLR) and platelet/lymphocyte (PLR) ratios were calculated as inflammatory parameters derived from the blood tests. COVID-19 patients presented lower high-density lipoprotein cholesterol (HDL-c) (47.90 ± 1.543 vs. 51.40 ± 0.992) and higher PLR (190.9 ± 9.410 vs. 137.6 ± 5.534) and NLR (3.40 ± 0.22 vs. 2.80 ± 0.15). Both NLR and PLR correlated with each other (r = 0.639). Furthermore, the Apo B/Apo A-I ratio was correlated with PLR (r = 0.5818) and eGFR (r = -0.2630). COVID-19 patients classified as at high risk of developing acute myocardial infarction based on the Apo B/ Apo A-I ratio had higher values for sUr/sCr. Thus, serum apolipoproteins, PLR, and NLR could be related to renal dysfunction in COVID-19.

https://doi.org/10.1590/s2175-97902023e23293

Estudo bibliométrico da produção científica da Revista Brasileira de Geriatria e Gerontologia entre 2014 e 2019
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Cesário, Vanovya Alves Claudino

; Silva, Cícera Renata Diniz Vieira

; Soares, Juliana Pontes

; Mendonça, Paula Beatriz de Souza

; Reis, Mônica Karina Santos

; Lima, Kenio Costa de

Revista Brasileira de Geriatria e Gerontologia

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2021, Volume 24 N. 3 elocation e210092

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Descrever e analisar o perfil das publicações da Revista Brasileira de Geriatria e Gerontologia (RBGG) entre 2014 e 2019. Método Trata-se de um estudo bibliométrico da produção científica da RBGG, durante o período de janeiro de 2014 a dezembro de 2019. A coleta de dados foi realizada por quatro pesquisadoras independentes, previamente treinadas e orientadas para a uniformização desse processo. Os dados coletados foram dispostos numa planilha no Microsoft Excel® e analisados no programa Stata versão 10.0. As variáveis analisadas foram organizadas em quatro eixos: identificação da publicação; tipo de estudo; autores; e processo editorial. Resultados Publicou-se um total de 504 estudos de 2014 a 2019, destes, 75% são artigos originais e 13,49% de revisão, 95,4% dos autores eram de nacionalidade brasileira e as instituições de afiliação eram majoritariamente do Sudeste (41,8%) e Sul (28,68%). A abordagem quantitativa foi predominante (70,5%) e as temáticas que se destacaram foram saúde pública (33,1%), doenças (19,9%) e assistência em saúde (19,4%). O tempo de aprovação apresentou uma redução média de quatro meses e o de publicação três meses. Conclusão Houve um aumento no número de publicações durante o período analisado, com destaque para artigos originais e estudos quantitativos. A diversidade de temas revela a tendência mais abrangente, para além daquelas centradas na doença, e mais para processos biopsicossociais e comportamentais, conforme verificado nos estudos em saúde pública. O processo editorial tem se mostrado célere com redução expressiva no tempo entre o recebimento e a publicação, e aumento no quantitativo de aprovação dos artigos recebidos.

Abstract Objective To describe and analyze the profile of publications of the Revista Brasileira de Geriatria e Gerontologia (RBGG) from 2014 to 2019. Method This is a bibliometric study of the scientific production of RBGG, during the period from January 2014 to December 2019. Data collection was performed by four independent researchers, previously trained and oriented to standardize this process. The collected data were arranged in a spreadsheet in Microsoft Excel® and analyzed using the Stata version 10.0 program. The analyzed variables were organized into four axes: Publication identification; Kind of study; Authors; and Editorial process. Results A total of 504 studies were published from 2014 to 2019, of which 75% are original articles and 13.49% reviews, 95.4% of the authors were Brazilian nationals and affiliation institutions were mostly in the Southeast (41.8%) and South (28.68%). The quantitative approach (70.5%) was predominant and the themes that stood out were public health (33.1%), diseases (19.9%), and health care (19.4%). The approval time showed a reduction lasted an average of four months and the publication three months. Conclusion There was an increase in the number of publications during the analyzed period, with emphasis on original articles and quantitative studies. The diversity of themes reveals the most common trend, beyond those centered on the disease, and more towards biopsychosocial and behavioral processes, as verified in studies in public health. The editorial process was rapid with a significant reduction in the time between receipt and publication, and an increase in the amount of approval of the articles received.

https://doi.org/10.1590/1981-22562021024.210092 40 downloads

McConnell patellar taping on postural control of women with patellofemoral pain syndrome: randomized clinical trial
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Ferreira, Daiene Cristina

; Silva Junior, Rubens Alexandre da

; Araújo, Cynthia Gobbi Alves

; Mantovani, Paula Renata

; Macedo, Christiane de Souza Guerino

Fisioterapia em Movimento

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2020, Volume 33 elocation e003357

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Os efeitos do taping patelar de McConnell (TPM) para o controle postural de mulheres com síndrome da dor patelofemoral (SDPF) são controversos. Objetivo: Avaliar os efeitos do TPM no controle postural estático unipodal e agachamento unipodal em mulheres com SDPF. Método: O estudo é um ensaio clínico randomizado-cego, que avaliou 40 mulheres com SDPF, e idade entre 18 e 35 anos. A amostra foi randomizada em dois grupos: grupo taping patelar de McConnell (GTPM) e grupo placebo (GP). Avaliou-se o controle postural em apoio estático e agachamento unipodal, no membro inferior com SDPF. O deslocamento do centro de pressão (CoP) foi registrado por plataforma de força, e analisado com os testes ANOVA two way e tamanho do efeito (Cohen’s d). Resultados: O controle postural estático não apontou diferenças significativas entre os grupos, tempos ou interação (P> 0,05); com pequeno tamanho de efeito. O controle postural em agachamento unipodal apresentou menor oscilação do centro de pressão para os dois grupos, com diferenças significativas em relação ao tempo de intervenção. No entanto, somente o GTPM demonstrou grande tamanho de efeito na frequência de oscilação e médio tamanho de efeito na velocidade de oscilação, durante o agachamento unipodal. Conclusão: O TPM e o placebo melhoraram o controle postural durante o agachamento unipodal. Deve-se observar que as mudanças e os tamanhos de efeito determinados para o GTPM foram significativamente maiores em relação ao GP, enfatizando sua importância clínica no tratamento de indivíduos com SDPF, durante atividades dinâmicas.

Abstract Introduction: The effects of McConnell patellar taping on the postural control of women with patellofemoral pain syndrome (PFPS) are controversial. Objective: To evaluate the effects of McConnell patellar taping on the static one-leg stance postural control and during squatting in women with PFPS. Method: A randomized, blinded clinical trial that comprised 40 women with PFPS, aged between 18 and 35 years. The study sample was allocated to two groups: McConnell patellar taping group (MPTG) and Placebo taping group (PTG). The analysis included the one-leg static support and squat on the lower limb with PFPS. The center of pressure (CoP) displacement parameters recorded by a force platform were analyzed using two-way ANOVA and Cohen’s d. Results: For the static postural control, no significant differences were found between the groups in terms of time or interaction (p>0.05); with small effect size. For the postural control during the one-leg squat, significant differences were found regarding the time of intervention for both groups, with reduced CoP parameters after the application of taping. However, the MPTG demonstrated a large effect size in frequency of oscillation and medium effect size in speed of oscillation, both during the squat exercise. Conclusion: McConnell patellar taping and placebo taping improved postural control during the one-leg squat. It should be observed that the changes and effect sizes determined for the MPTG were significantly higher compared to the PTG, emphasizing its clinical importance in the treatment of individuals with PFPS, during dynamic activities.

https://doi.org/10.1590/1980-5918.033.ao57 880 downloads

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro

; Alves, Ana Maroso

; Adania, Carolina Simone Souza

; Loch, Ana Paula

; Monroe, Aline Aparecida

; Souza, Rosa Alencar

; Gianna, Maria Clara

; Caminada, Sirlene

; Farias, Norma Suely de Oliveira

; Sousa, Paula de Oliveira e

; Domingues, Carmen Silva Bruniera

; Silva, Mariliza Henrique da

; Cervantes, Vilma

; Yamashiro, Juliana

; Caraciolo, Joselita Maria de Magalhães

; Silva, Fabiano Lima da

; Nemes Filho, Alexandre

; Jesus, Gabriel Lima de

; Helena, Ernani Tiaraju de Santa

; Albiero, José Francisco Gontan

; Lima, Marcela Soares Silveira

; Bellenzani, Renata

; Kehrig, Ruth Terezinha

; Vale, Felipe Campos do

; Nunes, Luceime Olivia

; Mendonça, Carolina Siqueira

; Zarili, Thais Fernanda Tortorelli

; Vilela, Mara Cristina

; Dantas, Jean Carlos de Oliveira

; Paula, Ivone de

; Tayra, Ângela

; Coelho, Débora Moraes

; Santos, Glauber Palha dos

; Quevedo, Dulce Castro

; Silva, Marcia Aparecida da

; Silva, Iraci Batista da

; Nasser, Mariana Arantes

; Andrade, Marta Campagnoni

; Santos, Maria Altenfelder

; Mercuri, Juliana

; Trindade, Katia Valeska

; Neves, Maria Aparecida Teixeira das

; Toledo, Renata Villanueva Alves de

; Almeida, Maria Cecília Rossi de

; Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Modelos de cuidado contínuo baseiam recentes estratégias em HIV, infecções sexualmente transmissíveis e hepatite C (HCV). Métodos: Desenvolveram-se modelos de contínuo do cuidado em HIV, HCV e sífilis congênita incluindo todas as etapas da atenção, desde a promoção e a prevenção até o controle clínico/cura. O modelo baseou a intervenção QualiRede, desenvolvida em parceria entre universidade e Sistema Único de Saúde (SUS), direcionada a gestores e demais profissionais de 6 regiões de saúde prioritárias em São Paulo e Santa Catarina. Selecionaram-se indicadores para cada etapa do contínuo do cuidado, provenientes dos sistemas de informação do SUS e dos questionários de avaliação de processo Qualiaids e QualiAB. Os indicadores formaram a base técnica de duas oficinas com profissionais e gestores de cada região: a primeira para identificar problemas e formar um Grupo Técnico Regional; e a segunda para construir planos de ação e metas a fim de melhorar o desempenho regional. Resultados: Os indicadores estão disponíveis no website www.qualirede.org. As oficinas ocorreram em quatro regiões de São Paulo (Alto Tietê, Baixada Santista, Grande ABC e Registro) e uma região de Santa Catarina (Foz do Rio Itajaí), resultando em planos regionais em São Paulo, mas não em Santa Catarina. Observou-se domínio limitado dos novos protocolos para HIV e HCV e uso incipiente de indicadores na rotina dos serviços. Conclusão: Melhorar o desempenho do contínuo do cuidado exige apropriação dos indicadores de desempenho e coordenação integrada dos fluxos de atenção em todos os níveis de gestão.

ABSTRACT Introduction: Care continuum models have supported recent strategies against sexually transmitted diseases, such as HIV and Hepatitis C (HCV). Methods: HIV, HCV, and congenital syphilis care continuum models were developed, including all stages of care, from promotion/prevention to clinical control/cure. The models supported the intervention QualiRede, developed by a University-Brazilian National Health System (SUS) partnership focused on managers and other professionals from six priority health regions in São Paulo and Santa Catarina. Indicators were selected for each stage of the care continuum from the SUS information systems and from the Qualiaids and QualiAB facility’s process evaluation questionnaires. The indicators acted as the technical basis of two workshops with professionals and managers in each region: the first one to identify problems and to create a Regional Technical Group; and the second one to design action plans for improving regional performance. Results: The indicators are available at www.qualirede.org. The workshops took place in the regions of Alto Tietê, Baixada Santista, Grande ABC, and Registro (São Paulo) and of Foz do Rio Itajaí (Santa Catarina), which resulted in regional action plans in São Paulo, but not in Santa Catarina. A lack of awareness was observed regarding the new HIV and HCV protocols, as well as an incipient use of indicators in routine practices. Conclusion: Improving the performance of the care continuum requires appropriation of performance indicators and coordination of care flows at local, regional, and state levels of management.

https://doi.org/10.1590/1980-549720190010.supl.1

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro

; Alves, Ana Maroso

; Adania, Carolina Simone Souza

; Loch, Ana Paula

; Monroe, Aline Aparecida

; Souza, Rosa Alencar

; Gianna, Maria Clara

; Caminada, Sirlene

; Farias, Norma Suely de Oliveira

; Sousa, Paula de Oliveira e

; Domingues, Carmen Silva Bruniera

; Silva, Mariliza Henrique da

; Cervantes, Vilma

; Yamashiro, Juliana

; Caraciolo, Joselita Maria de Magalhães

; Silva, Fabiano Lima da

; Nemes Filho, Alexandre

; Jesus, Gabriel Lima de

; Helena, Ernani Tiaraju de Santa

; Albiero, José Francisco Gontan

; Lima, Marcela Soares Silveira

; Bellenzani, Renata

; Kehrig, Ruth Terezinha

; Vale, Felipe Campos do

; Nunes, Luceime Olivia

; Mendonça, Carolina Siqueira

; Zarili, Thais Fernanda Tortorelli

; Vilela, Mara Cristina

; Dantas, Jean Carlos de Oliveira

; Paula, Ivone de

; Tayra, Ângela

; Coelho, Débora Moraes

; Santos, Glauber Palha dos

; Quevedo, Dulce Castro

; Silva, Marcia Aparecida da

; Silva, Iraci Batista da

; Nasser, Mariana Arantes

; Andrade, Marta Campagnoni

; Santos, Maria Altenfelder

; Mercuri, Juliana

; Trindade, Katia Valeska

; Neves, Maria Aparecida Teixeira das

; Toledo, Renata Villanueva Alves de

; Almeida, Maria Cecília Rossi de

; Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720190010.supl.1 2475 downloads

Draft genome sequence of Paraburkholderia tropica Ppe8 strain, a sugarcane endophytic diazotrophic bacterium
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Silva, Paula Renata Alves da

; Simões-Araújo, Jean Luiz

; Vidal, Márcia Soares

; Cruz, Leonardo Magalhães

; Souza, Emanuel Maltempi de

; Baldani, José Ivo

Brazilian Journal of Microbiology

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jun 2018, Volume 49 N. 2 Pages 210 - 211

Abstract: En | Text: En | PDF: En

Abstract Paraburkholderia tropica (syn Burkholderia tropica) are nitrogen-fixing bacteria commonly found in sugarcane. The Paraburkholderia tropica strain Ppe8 is part of the sugarcane inoculant consortium that has a beneficial effect on yield. Here, we report a draft genome sequence of this strain elucidating the mechanisms involved in its interaction mainly with Poaceae. A genome size of approximately 8.75 Mb containing 7844 protein coding genes distributed in 526 subsystems was de novo assembled with ABySS and annotated by RAST. Genes related to the nitrogen fixation process, the secretion systems (I, II, III, IV, and VI), and related to a variety of metabolic traits, such as metabolism of carbohydrates, amino acids, vitamins, and proteins, were detected, suggesting a broad metabolic capacity and possible adaptation to plant association.

https://doi.org/10.1016/j.bjm.2017.07.005 815 downloads

Pain and musculoskeletal discomfort in physiotherapists of the intensive care unit and ward of a university hospital: a retrospective cohort study
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Santos, Renata Maria Eloi dos

; Maduro, Paula Andreatta

; Silva, Tarcísio Fulgêncio Alves da

; Trombini-Souza, Francis

BrJP

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jun 2018, Volume 1 N. 2 Pages 127 - 133

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO JUSTIFICATIVA E OBJETIVOS: Tanto os fatores biomecânicos quanto emocionais podem contribuir para o surgimento de distúrbios osteomusculares em fisioterapeutas que atuam dentro de um hospital; porém ainda não se sabe se esses profissionais apresentam dor e desconforto musculoesquelético relacionados ao setor e ao tempo de trabalho. Os objetivos deste estudo foram comparar o autorrelato de dor e o desconforto musculoesquelético dos fisioterapeutas da unidade de terapia intensiva e enfermarias e avaliar retrospectivamente, em 12 meses de trabalho, o autorrelato de dor e desconforto musculoesquelético dos fisioterapeutas desses setores. MÉTODOS: O autorrelato de dor e o desconforto musculoesquelético dos 18 fisioterapeutas que atuam nesse hospital foi avaliado pelo Questionário Nórdico de Sintomas Osteomusculares, no período atual (T1) e comparados retrospectivamente com os dados avaliados no período admissional (T0). RESULTADOS: Não houve associação entre o autorrelato de dor e o desconforto musculoesquelético e os setores de atuação desses profissionais, porém houve uma associação temporal entre o autorrelato de dor e o desconforto musculoesquelético na unidade de terapia intensiva, nas regiões de pescoço (p=0,043), ombros (p=0,009), parte superior das costas (p=0,043), parte inferior das costas (p=0,043) e região de quadril e coxas (p=0,027). A segunda jornada de trabalho desses fisioterapeutas não se mostrou associada com a dor e o desconforto musculoesquelético. CONCLUSÃO: O autorrelato de dor e desconforto musculoesquelético de fisioterapeutas desse hospital universitário, tanto no período admissional (T0) quanto após 12 meses de trabalho (T1) não se mostrou associado com o setor de atuação desses profissionais. Depois de 12 meses, os fisioterapeutas da unidade de terapia intensiva apresentaram aumento no autorrelato de dor e desconforto musculoesquelético.

ABSTRACT BACKGROUND AND OBJECTIVES: Both biomechanical and emotional factors may contribute to the development of work-related musculoskeletal disorders in physical therapists working at a hospital, but we still do not know if these professionals present musculoskeletal symptoms related to the sector and working time. The objective of this study was to compare the self-report of pain and musculoskeletal discomfort of the physical therapists working in the intensive care unit and ward of a university hospital and retrospectively evaluate, 12 months of work, self-report of pain and musculoskeletal discomfort of physiotherapists in these sectors. METHODS: The self-report of pain and the musculoskeletal discomfort of the 18 physical therapists working in this hospital were evaluated by the Nordic Musculoskeletal Questionnaire in the admission period (T0) and after 12 months (T1). RESULTS: No association was found between the self-report of pain and musculoskeletal discomfort and the working sector of these professionals. However, there was a temporal association between the self-report of pain and musculoskeletal complaints in the intensive care unit sector in the following regions: neck (p=0.043), shoulders (p=0.009), upper back (p=0.043), lower back (p=0.043) and hip and thigh region (p=0.027). The second shift of these professionals was not associated with pain and musculoskeletal discomfort. CONCLUSION: The self-report of pain and musculoskeletal discomfort of physical therapists of this university hospital, both in the admission period (T0) and after 12 months of work (T1) was not associated with the sector in which they work. However, after 12 months, the physical therapists working in the intensive care unit showed an increase in the amount of self-report of pain and musculoskeletal discomfort.

https://doi.org/10.5935/2595-0118.20180025 3039 downloads

10.

Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis
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Machado-Neto, João Agostinho

; Fenerich, Bruna Alves

; Rodrigues Alves, Ana Paula Nunes

; Fernandes, Jaqueline Cristina

; Scopim-Ribeiro, Renata

; Coelho-Silva, Juan Luiz

; Traina, Fabiola

Clinics

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2018, Volume 73 elocation e566s

Abstract: En | Text: En | PDF: En

The insulin receptor substrate (IRS) proteins are a family of cytoplasmic proteins that integrate and coordinate the transmission of signals from the extracellular to the intracellular environment via transmembrane receptors, thus regulating cell growth, metabolism, survival and proliferation. The PI3K/AKT/mTOR and MAPK signaling pathways are the best-characterized downstream signaling pathways activated by IRS signaling (canonical pathways). However, novel signaling axes involving IRS proteins (noncanonical pathways) have recently been identified in solid tumor and hematologic neoplasm models. Insulin receptor substrate-1 (IRS1) and insulin receptor substrate-2 (IRS2) are the best-characterized IRS proteins in hematologic-related processes. IRS2 binds to important cellular receptors involved in normal hematopoiesis (EPOR, MPL and IGF1R). Moreover, the identification of IRS1/ABL1 and IRS2/JAK2V617F interactions and their functional consequences has opened a new frontier for investigating the roles of the IRS protein family in malignant hematopoiesis. Insulin receptor substrate-4 (IRS4) is absent in normal hematopoietic tissues but may be expressed under abnormal conditions. Moreover, insulin receptor substrate-5 (DOK4) and insulin receptor substrate-6 (DOK5) are linked to lymphocyte regulation. An improved understanding of the signaling pathways mediated by IRS proteins in hematopoiesis-related processes, along with the increased development of agonists and antagonists of these signaling axes, may generate new therapeutic approaches for hematological diseases. The scope of this review is to recapitulate and review the evidence for the functions of IRS proteins in normal and malignant hematopoiesis.

https://doi.org/10.6061/clinics/2018/e566s 3018 downloads

11.

Dark septate endophyte decreases stress on rice plants
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Santos, Silvana Gomes dos

; Silva, Paula Renata Alves da

; Garcia, Andres Calderin

; Zilli, Jerri Édson

; Berbara, Ricardo Luis Louro

Brazilian Journal of Microbiology

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jun 2017, Volume 48 N. 2 Pages 333 - 341

Abstract: En | Text: En | PDF: En

Abstract Abiotic stress is one of the major limiting factors for plant development and productivity, which makes it important to identify microorganisms capable of increasing plant tolerance to stress. Dark septate endophytes can be symbionts of plants. In the present study, we evaluated the ability of dark septate endophytes isolates to reduce the effects of water stress in the rice varieties Nipponbare and Piauí. The experiments were performed under gnotobiotic conditions, and the water stress was induced with PEG. Four dark septate endophytes were isolated from the roots of wild rice (Oryza glumaepatula) collected from the Brazilian Amazon. Plant height as well as shoot and root fresh and dry matter were measured. Leaf protein concentrations and antioxidant enzyme activity were also estimated. The dark septate endophytes were grown in vitro in Petri dishes containing culture medium; they exhibited different levels of tolerance to salinity and water stress. The two rice varieties tested responded differently to inoculation with dark septate endophytes. Endophytes promoted rice plant growth both in the presence and in the absence of a water deficit. Decreased oxidative stress in plants in response to inoculation was observed in nearly all inoculated treatments, as indicated by the decrease in antioxidant enzyme activity. Dark septate endophytes fungi were shown to increase the tolerance of rice plants to stress caused by water deficiency.

https://doi.org/10.1016/j.bjm.2016.09.018 1384 downloads

12.

A telemedicine network for remote paediatric cardiology services in north-east Brazil
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Mattos, Sandra da Silva

; Hazin, Sheila Maria Vieira

; Regis, Cláudio Teixeira

; Araújo, Juliana Sousa Soares de

; Albuquerque, Fernanda Cruz de Lira

; Moser, Lúcia Roberta Didier Nunes

; Hatem, Thamine de Paula

; Freitas, Carolina Paim Gomes de

; Mourato, Felipe Alves

; Tavares, Thiago Ribeiro

; Gomes, Renata Grigório Silva

; Severia, Rossan

; Santosa, Cícera Rocha

; Silva, Jailson Ferreira da

; Rezende, Juliana Landim

; Vieira, Paulo Coelho

; Lima Filho, José Luiz de

Bulletin of the World Health Organization

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dec 2015, Volume 93 N. 12 Pages 881 - 887

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Abstract Problem Providing health care for children with congenital heart diseases remains a major challenge in low- and middle-income countries. Approach In October 2011, the Government of Paraíba, Brazil, established a paediatric cardiology network in partnership with the nongovernmental organization Círculo do Coração. A cardiology team supervised all network activities, using the Internet to keep in contact with remote health facilities. The network developed protocols for screening heart defects. Echocardiograms were performed by physicians under direct online supervision of a cardiologist; alternatively, a video recording of the examination was subsequently reviewed by a cardiologist. Cardiovascular surgeons came to a paediatric hospital in the state capital once a week to perform heart surgeries. Local setting Until 2011, the State of Paraíba had no structured programme to care for children with heart disease. This often resulted in missed or late diagnosis, with adverse health consequences for the children. Relevant changes From 2012 to 2014, 73 751 babies were screened for heart defects and 857 abnormalities were identified. Detection of congenital heart diseases increased from 4.09 to 11.62 per 1000 live births ( P< 0.001). Over 6000 consultations and echocardiograms were supervised via the Internet. Time to diagnosis, transfers and hospital stays were greatly reduced. A total of 330 operations were carried out with 6.7% (22/330) mortality. Lessons learnt Access to an echocardiography machine with remote supervision by a cardiologist improves the detection of congenital heart disease by neonatologists; virtual outpatient clinics facilitate clinical management; the use of Internet technology with simple screening techniques allows resources to be allocated more efficiently.

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résumé est disponible dans le document

https://doi.org/10.2471/BLT.14.148874 2636 downloads

13.

Factors associated to the imposition of types of violence against women informed in sentry services
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Vieira, Luiza Jane Eyre de Souza

; Ferreira, Renata Carneiro

; Moreira, Gracyelle Alves Remigio

; Gondim, Ana Paula Soares

; Araujo, Maria Alix Leite

; Silva, Raimunda Magalhães da

Revista Latino-Americana de Enfermagem

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jul 2013, Volume 21 N. 4 Pages 920 - 927

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

OBJECTIVE: to identify the prevalence and the factors associated to the imposition of the different types of violence against women informed in sentry services. METHOD: transversal study accomplished through 939 notification forms of cases of violence against women, referring to the three years from 2006 to 2008 in Fortaleza, Ceará. Univariate and multiple analyses by logistic regression were realized. RESULT: the results showed a positive association between the imposition of types of violence against women with a schooling varying from illiterate to basic education and the aggression which had occurred other times. CONCLUSION: this knowledge contributes to the delineation of specific actions that aim at facing this problem, as well as generates subsidies for adequate attendance proposals and guidance for the victims who call on health services.

OBJETIVO: identificar la prevalencia y los factores asociados a la sobreposición de los diferentes tipos de violencia contra la mujer notificados en servicios centinela. MÉTODO: estudio transversal realizado con 939 fichas de notificación de casos de violencia contra la mujer, referentes al trienio de 2006 a 2008, en Fortaleza, Ceará. Fueron realizados el análisis univariado y el múltiple por regresión logística. RESULTADOS: los resultados mostraron asociación positiva entre la sobreposición de tipos de violencia contra la mujer, con la escolaridad variando de analfabeta a enseñanza fundamental y la agresión haber ocurrido otras veces. CONCLUSIÓN: este conocimiento contribuye para el delineamiento de acciones específicas que tengan por objetivo enfrentar esta problemática, así como generar subsidios para elaborar una propuesta adecuada de atención y encaminamiento de las víctimas que buscan los servicios de salud.

OBJETIVO: identificar a prevalência e os fatores associados à sobreposição dos diferentes tipos de violência contra a mulher, notificada em serviços sentinela. MÉTODO: estudo transversal, realizado com 939 fichas de notificação de casos de violência contra a mulher, referentes ao triênio de 2006 a 2008, em Fortaleza, Ceará. Análises univariada e múltipla por regressão logística foram realizadas. RESULTADO: os resultados mostraram associação positiva entre a sobreposição de tipos de violência contra a mulher com a escolaridade variando de analfabeta a ensino fundamental e a agressão ter ocorrido outras vezes. CONCLUSÃO: esse conhecimento contribui para o delineamento de ações específicas que visam o enfrentamento dessa problemática, assim como gera subsídios para proposta adequada de atendimento e encaminhamento das vítimas que buscam os serviços de saúde.

https://doi.org/10.1590/S0104-11692013000400013 3 downloads

14.

Factors associated to the imposition of types of violence against women informed in sentry services
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Vieira, Luiza Jane Eyre de Souza

; Ferreira, Renata Carneiro

; Moreira, Gracyelle Alves Remigio

; Gondim, Ana Paula Soares

; Araujo, Maria Alix Leite

; Silva, Raimunda Magalhães da

Revista Latino-Americana de Enfermagem

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jul 2013, Volume 21 N. 4 Pages 920 - 927

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/S0104-11692013000400013 9352 downloads

15.

Use of cyanoacrylate in the coaptation of edges of surgical wounds
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Lins, Ruthinéia Diógenes Alves Uchôa

; Gomes, Raquel Christina Barboza

; Santos, Kátia Simone Alves dos

; Silva, Paula Vanessa da

; Silva, Renata Torres Moreira da

; Ramos, Ianny Alves

Anais Brasileiros de Dermatologia

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dec 2012, Volume 87 N. 6 Pages 871 - 876

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O cianoacrilato tem sido utilizado em diversos campos das especialidades cirúrgicas como adesivo no fechamento de retalhos gengivais e em lacerações mucosas e cutâneas, além de apresentar uma ótima resposta imunológica. Tendo em vista as necessidades estéticas, o cianoacrilato tem sido aplicado com resultados satisfatórios quando comparado aos fios de sutura, pois apresenta melhor capacidade de coaptação das bordas de uma lesão de pele e mucosa, menor cicatriz residual e biocompatiblidade, estando limitado, entretanto, a zonas de baixa tensão tecidual. Frente a tais considerações, o presente trabalho busca desenvolver uma revisão literária, objetivando revelar as vantagens do uso dos adesivos teciduais, especialmente os cianoacrilatos, na coaptação de feridas, em detrimento da utilização dos métodos convencionais com fios de sutura.

Cyanoacrylate has been used in several fields of different surgical specialties as an adhesive for closure of gingival flaps and in mucous and cutaneous lacerations. One of its advantages is that it has an excellent immunological response. In view of aesthetic needs, cyanoacrylate has been applied with satisfactory results, when compared with sutures. It presents better coaptation of edges of cutaneous and mucosal lesions, smaller residual scars, and biocompatibility. However, it is limited to areas of little tissue tension. This work attempts to provide a literature review with the aim of revealing the advantages of using tissue adhesives, especially cyanoacrylates, in wound coaptation in comparison with conventional methods.

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