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Abstract Large quantities of residual cooking oil are being increasingly generated in various sectors, as it is often improperly disposed of and causes serious environmental problems. A commonly used alternative is the use of lipases in enzymatic hydrolysis, since it is rather attractive to several sectors, in addition to allowing the use of products generated thereof, such as: free fatty acids, diacylglycerols, monoacylglycerols and free glycerol, moreover, it is capable of operating in mild temperature and pressure conditions. Therefore, the present study aimed to evaluate alternatives for the hydrolysis of residual frying oil by evaluating the efficiency of different types of supports and heating systems using free and immobilized forms of lipase from Burkholderia cepacia (BCL) and Porcine pancreas (PPL) as biocatalyst. Polyhydroxybutyrate (PHB), niobium oxide (Nb2O5) and chitosan (CHIT) were evaluated as support for immobilizing BCL and PPL lipases, and superior results were found regarding the hydrolytic activity of immobilization derivatives using PHB and Nb2O5. Among the heating systems under evaluation, the highest percentage of residual oil hydrolysis was found using the ultrasound system for both free and immobilized lipases, reaching 57.91% hydrolysis for lipases immobilized on Nb2O5 and 61.11% hydrolysis for the derivative immobilized on PHB. The operational stability of both biocatalysts was evaluated using similar half-life time values for both. Thus, it was observed that the ultrasound system was efficient in improving lipase performance in the hydrolysis of free fatty acids, once this unconventional heating system is quite promising for accelerating such enzymatic reactions.

https://doi.org/10.1590/1678-4324-2024220625

Dysfunctional suction dynamics in newborns with ankyloglossia
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Cunha, Bruna Mendes Lourenço

; Badarane, Erika Baptista Luiz

; Sousa Filho, Paulo Vitor Melo

; Costa, Kauê Machado

; Silva Filho, Manoel da

CoDAS

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2024, Volume 36 N. 2 elocation e20230054

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose Compare infant suction in babies with and without ankyloglossia using a microprocessor-controlled pressure sensor coupled to a pacifier. Methods Fifty-five infants from 0 to 2 months of age underwent clinical examination for ankyloglossia, after which they were offered a silicone pacifier connected to the pressure acquisition device and suction activity was recorded. Thus, we extracted the frequency of sucks within a burst, the average suck duration, the burst duration, the number of sucks per burst, the maximum amplitude of sucks per burst and the inter-burst interval. Results The key difference in newborns with ankyloglossia in relation to control was that they perform longer bursts of suction activity. Conclusion The longer burst durations are likely a compensatory strategy and may underlie the pain reported by mothers during breastfeeding. We therefore propose a method for objectively quantifying some parameters of infant suction capacity and demonstrate its use in assisting the evaluation of ankyloglossia.

RESUMO Objetivo Comparar a sucção infantil em bebês com e sem anquiloglossia usando um sensor de pressão controlado por microprocessador acoplado a uma chupeta. Método Cinquenta e cinco lactentes de 0 a 2 meses de idade foram submetidos ao exame clínico de anquiloglossia, em seguida foi oferecido uma chupeta de silicone conectada ao dispositivo de aquisição de pressão e a atividade de sucção foi registrada. Assim, obtivemos dados sobre a frequência de sucções dentro de um período de sucções, a duração média da sucção, a duração da rajada, o número de sucções por rajada, a amplitude máxima das sucções por rajada e o intervalo entre rajadas. O teste t não pareado foi utilizado para comparações entre os grupos. Resultados A principal diferença dos recém-nascidos com anquiloglossia em relação aos do grupo controle é que eles realizam rajadas mais longas durante a atividade de sucção. Conclusão A duração mais longa das rajadas é provavelmente uma estratégia compensatória e pode estar por trás da dor relatada pelas mães durante a amamentação. Portanto, propomos um método para quantificar objetivamente alguns parâmetros da sucção infantil e demonstramos seu uso para auxiliar na avaliação da anquiloglossia.

https://doi.org/10.1590/2317-1782/20232023054

Calciphylaxis: a rare cause of limb ulcer - a case report
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Cunha, Roberto

; Silva, Manuel

; Carneiro, Vitor

; Sousa, Pedro

; Correia, Mafalda

; Vieira, Isabel

; Cássio, Isabel

; Oliveira, Nelson

; Dias, Emanuel

Angiologia e Cirurgia Vascular

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dec 2023, Volume 19 N. 4 Pages 235 - 238

Abstract: En | Text: En | PDF: En

Abstract Background: Calciphylaxis is a rare disease with a poor prognosis predominantly found in end-stage renal disease patients treated with dialysis. This pathology most commonly presents with painful non-healing ulcers, predisposing to high risk of sepsis and death. The authors present a case of bilateral leg ulcers due to calciphylaxis. Case report: A 40-year-old female patient presented with painful ulcers in both lower limbs, for two months. She had a history of end-stage renal disease, morbid obesity, severe hypertension, arterial fibrillation and secondary hyperparathyroidism. Duplex examination releveled biphasic curves in the foot arteries. The ankle-brachial index was carried out with a result of 1.1, obtaining a WIFi stage of 3 (2/0/2). Venous disease was excluded. A biopsy was obtained, revealing small thick-walled vessels with dystrophic calcification of the intima and media. After surgical debridement, antibiotics directed at the superimposed infection were administered and local wound care with chemical debridement was performed. The ulcers healed completely after 8 weeks and there was no recurrence after 6 months. Conclusion: The diagnosis is made by clinical and histological findings. Treatment involves a multidisciplinary approach with medical treatment and wound care. Drugs such as sodium thiosulphate and cinacalcet have shown good results in the healing of ulcers. Vascular surgeons, as they often deal with patients with leg ulcers, should be aware of calciphylaxis as a differential diagnosis when vascular disease is excluded.

https://doi.org/10.48750/acv.546

[SciELO Preprints] - Wage differences of rural and urban workers in the states of Amazonas and Pará
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Wendhausen, Enimar Jerônimo Brasil , Marília Carvalho Alves, Frederick Fagundes Sousa, Lucas Vitor de Carvalho

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Publication date: 2023-10-16

Abstract: En Pt

This paper analyses the salary differences between rural and urban workers in the states of Amazonas and Pará. This analysis was conducted for the two largest states in northern Brazil, as they have different socioeconomic and labor market characteristics. Specifically, we examine the extent to which investment in human capital and non-productive attributes affect income differences. We used the Continuous National Household Sample Survey for 2011, 2013, and 2015. We find that highly educated and experienced workers obtain higher wage increases through the fixed-effects pseudo-panel and Oaxaca-Blinder methodologies. Urban workers earn higher wages than rural workers, as well as those residing in the state of Pará. In the state of Amazonas, the wage difference is impacted by non-productive attributes explained by segmentation in the labor market, such as government administration and other activities in contrast to the agricultural sector.

Este artigo analisa as diferenças salariais entre trabalhadores rurais e urbanos do Amazonas e do Pará. Esta análise foi feita para os dois maiores estados da região Norte por possuírem características socioeconômicas e de mercado de trabalho distintas. Especificamente, verificou-se até que ponto o investimento em capital humano e os atributos não produtivos impactam as diferenças de rendimentos. Utilizou-se a Pesquisa Nacional por Amostra de Domicílios Contínua para 2011, 2013 e 2015. Através das metodologias de pseudopainel com Efeitos Fixos e Oaxaca-Blinder verificou-se que os trabalhadores mais escolarizados e experientes obtêm maiores ganhos salariais. Os trabalhadores urbanos recebem maiores salários do que os trabalhadores rurais, bem como aqueles que residem no Pará. No estado do Amazonas, o que impactou a diferença salarial foram os atributos não produtivos explicados pela segmentação no mercado de trabalho, como a Administração Pública e Outras Atividades em comparação com o setor Agrícola.

https://doi.org/10.1590/0103-6351/7687

“Não temos de carregar o que não é nosso” Recensão de Um cão no meio do caminho, de Isabela Figueiredo. Lisboa: Leya/Caminho, 2022, 292 pp.
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Sousa, Vítor de

Ex aequo

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jun 2023, N. 47 Pages 246 - 250

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.22355/exaequo.2023.47.18

Rastreio da Malnutrição nos Cuidados de Saúde Primários
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Lopes, Paulo André

; Roque, Ana Carolina

; Sacramento, Ana Luísa

; Valentim, Bruno

; Gonçalves, Catarina Vieira

; Lourenço, Cristiane

; Costa, Fábio Leite

; Roque, Joana

; Grácio, João

; Agrela, Pedro

; Lopes, Pedro Tiago

; Marinho, Ricardo Cleto

; Ramos de Sousa, Ricardo

; Viana, Rita

; Ferreira, Vitor Hugo

; Veríssimo, Manuel Teixeira

; Tarantino, Silvia

; Marinho, Aníbal

Medicina Interna

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jun 2023, Volume 30 N. 2 Pages 47 - 55

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract In the community, malnutrition is manifested by the loss of muscle mass, being associated with a decrease in muscle strength, an increased risk of frailty, functional impairment and impaired healing of chronic wounds, as well as a higher incidence of infections. It is estimated that malnutrition affects one in three elderly people at home and one in three patients in elderly care institutions. Malnutrition is reversible as long as the patient has access to timely nutritional screening that identifies their nutritional risk and as long as an individualized nutritional intervention is instituted. Disease associated malnutrition continues to be perceived as a secondary problem in primary health care, so the implementation of nutritional risk screening, as a routine parameter, is the first step in improving access to nutritional care in the community. In this article, the Malnutrition Universal Screening Tool is proposed for routine nutritional screening in primary care.

Resumo Na comunidade, a malnutrição manifesta-se pela perda de massa muscular, estando associada à diminuição da força muscular, ao aumento do risco de fragilidade, ao comprometimento funcional e da cicatrização de feridas crónicas, assim como a maior incidência de infeções. Estima-se que a malnutrição afete um em cada três idosos no seu domicílio e um em cada três utentes em instituições de cuidados de idosos. A malnutrição é reversível desde que o utente tenha acesso a um atempado rastreio nutricional que identifique o seu risco nutricional e instituída uma intervenção nutricional individualizada. A malnutrição associada à doença continua a ser percecionada como um problema secundário nos cuidados de saúde primários, pelo que a implementação do rastreio do risco nutricional, como um parâmetro de rotina, é o primeiro passo na melhoria do acesso aos cuidados nutricionais na comunidade. Neste artigo, é proposta a ferramenta Malnutrition Universal Screening Tool para rastreio nutricional de rotina nos cuidados de saúde primários.

https://doi.org/10.24950/rspmi.1055

Growth and physiology of ‘Sunrise’ papaya seedlings in response to salinity and humic acid
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Targino, Vitor A.

; Lopes, Adriano S.

; Sousa, Valéria F. de O.

; Henschel, Juliane M.

; Silva, João H. B. da

; Rodrigues, Lucas S.

; Medeiros, Wiliana J. F. de

; Batista, Diego S.

; Dias, Thiago J.

Revista Brasileira de Engenharia Agrícola e Ambiental

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may 2023, Volume 27 N. 5 Pages 352 - 358

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Salinity is one of the major obstacles to agriculture in semi-arid regions, as it affects the physiological processes, growth, and yield of numerous crops. Hence, the application of salt stress attenuators is of paramount importance, as it enables the use of saline water for agricultural purposes. Among these, humic acid promotes the growth as well as water and nutrient uptake of plants. To this end, the present study evaluated the effects of humic acid on the growth and physiology of Carica papaya seedlings irrigated with saline water. The experiment followed the randomized block design with five levels of electrical conductivity (0.5, 1.15, 2.75, 4.35, and 5.0 dS m-1) and five concentrations of humic acid (0.5, 0.94, 2.0, 3.06, and 3.5 mL L-1). Growth, gas exchange, chlorophyll content, and chlorophyll a fluorescence were evaluated. Irrigation with 4.9 dS m-1 water and application of 3.05 mL L-1 humic acid promoted the growth of papaya seedlings. Irrigation with high-salinity water (4.96 and 3.09 dS m-1) coupled with the application of 3.05 and 2.21 mL L-1 humic acid increased internal CO2 concentration, transpiration, instantaneous water use efficiency, carboxylation efficiency, and chlorophyll b content. Overall, humic acid (3.5 mL L-1) attenuated the deleterious effects of salt stress, promoting the growth and improving the performance of papaya seedlings under moderate salinity (4 dS m-1).

RESUMO A salinidade é um dos grandes entraves na agricultura em regiões semiáridas, pois afeta os processos fisiológicos, crescimento e produção de diversas culturas. Assim, o uso de atenuadores do estresse salino é de extrema importância, pois permite o uso de águas salinas para fins agrícolas. Dentre estes, destacam-se os ácidos húmicos que promovem o crescimento e a absorção de água e nutrientes. Assim, o objetivo deste trabalho foi avaliar o efeito do ácido húmico sob o crescimento e a fisiologia de mudas de mamão irrigadas com água salina. O delineamento experimental utilizado foi em blocos casualizados com cinco níveis de condutividade elétrica (0,5; 1,15; 2,75; 4,35 e 5,0 dS m-1), e cinco concentrações de ácido húmico (0,5; 0,94; 2,0; 3,06 e 3,5 mL L-1). Foram avaliados o crescimento, trocas gasosas, índice de clorofilas e fluorescência da clorofila a. A irrigação com água de 4,9 dS m-1 e aplicação de 3,05 mL L-1 de ácido húmico proporcionou maior crescimento das mudas de mamoeiro. A irrigação de mudas de mamoeiro com alta salinidade (4,96 e 3,09 dS m-1) aliada à aplicação de 3,05 e 2,21 mL L-1 de ácido húmico proporcionou aumento da concentração interna de CO2, taxa de transpiração, eficiência instantânea do uso da água, eficiência de carboxilação e teor de clorofila b. O ácido húmico (3,5 mL L-1) atenua os efeitos deletérios da salinidade no mamoeiro, sendo capaz de aumentar o crescimento e melhorar o desempenho das mudas de mamão em salinidade moderada (4 dS m-1).

https://doi.org/10.1590/1807-1929/agriambi.v27n5p352-358

THE USE OF AUTOLOGOUS BLOOD TRANSFUSION IN DIGESTIVE TRACT SURGERY: A LITERATURE REVIEW
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GAMA, João Vitor Ponciano

; FERREIRA, Rian Magro

; LIMA, Leonardo Portugal

; NEVES, Thaís Rodrigues

; DIAS, João Pedro Gonçalves

; SOUSA FILHO, Gilvando Dias de

Arquivos de Gastroenterologia

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jan 2023, Volume 60 N. 1 Pages 137 - 143

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Background: The use of autologous blood transfusion in digestive tract surgeries, whether after preoperative blood collection or intraoperative blood salvage, is an alternative to allogeneic blood, which brings with it certain risks and shortage, due to the lack of donors. Studies have shown lower mortality and longer survival associated with autologous blood, however the theoretical possibility of spreading metastatic disease is still one of the limiting factors of its use. Objective: To evaluate the application of autologous transfusion in digestive tract surgeries, noting the benefits, damages and effects on the spread of metastatic disease. Methods: This is an integrative review of the literature available in the PubMed, Virtual Health Library and SciELO databases, by searching for “Autologous Blood Transfusion AND Gastrointestinal Surgical Procedures”. Observational and experimental studies and guidelines published in the last five years in Portuguese, English or Spanish were included. Results: Not all patients benefit from blood collection before elective procedures, with the time of surgery and hemoglobin levels some of the factors that may indicate the need for preoperative storage. Regarding the intraoperative salvaged blood, it was observed that there is no increased risk of tumor recurrence, but the importance of using leukocyte filters and blood irradiation is highlighted. There was no consensus among the studies whether there is a maintenance or reduction of complication rates compared to allogeneic blood. The cost related to the use of autologous blood may be higher, and the less stringent selection criteria prevent it from being added to the general donation pool. Conclusion: There were no objective and concordant answers among the studies, but the strong evidence of less recurrence of digestive tumors, the possibility of changes in morbidity and mortality, and the reduction of costs with patients suggest that the practice of autologous blood transfusion should be encouraged in digestive tract surgeries. It is necessary to note if the deleterious effects would stand out amidst the possible benefits to the patient and to health care systems.

RESUMO Contexto: O emprego da transfusão sanguínea autóloga nas cirurgias do aparelho digestivo, seja através da coleta de sangue no pré-operatório ou da recuperação de sangue no intraoperatório, é uma alternativa ao sangue alogênico, que traz consigo determinados riscos e a escassez, pela falta de doadores. Estudos têm demonstrado menor mortalidade e maior sobrevida associadas ao sangue autólogo, no entanto a possibilidade teórica de propagação de doença metastática ainda é um dos fatores limitantes do seu uso. Objetivo: Avaliar a aplicação da transfusão autóloga em cirurgias do aparelho digestivo, observando os benefícios, prejuízos e efeitos sobre a propagação de doenças metastáticas. Métodos: Trata-se de uma revisão integrativa da literatura disponível nas bases de dados PubMed, Biblioteca Virtual em Saúde e SciELO, através da busca por “Autologous Blood Transfusion AND Gastrointestinal Surgical Procedures”. Foram incluídos estudos observacionais e experimentais e guidelines publicados nos últimos 5 anos, nos idiomas português, inglês ou espanhol. Resultados: Nem todos os pacientes beneficiam-se da coleta de sangue antes de procedimentos eletivos, sendo o tempo de cirurgia e os níveis de hemoglobina alguns dos fatores que podem indicar a necessidade do armazenamento pré-operatório. Em relação ao sangue recuperado no intraoperatório, observou-se que não há maior risco de recorrência de tumores, mas destaca-se a importância do uso de filtros leucocitários e irradiação sanguínea. Não houve consenso entre os estudos se há uma manutenção ou redução das taxas de complicação, em comparação com o sangue alogênico. O custo relacionado ao uso de sangue autólogo pode ser maior, além de os critérios de seleção menos rigorosos impedirem que seja adicionado ao pool geral de doações. Conclusão: Não houve respostas objetivas e concordantes entre os estudos, mas os fortes indícios da menor recorrência de tumores digestivos, a possibilidade de alterações na morbimortalidade e a redução dos custos com os pacientes sugerem que a prática da transfusão sanguínea autóloga seja fomentada nas cirurgias do aparelho digestivo. É necessário observar se os efeitos deletérios se destacariam em meio aos possíveis benefícios ao paciente e aos sistemas de saúde.

https://doi.org/10.1590/s0004-2803.202301000-16

The use of serum alkaline phosphatase as a choledocholithiasis marker to mitigate the cost of magnetic resonance cholangiography
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Costa, Pedro Henrique Peixoto

; Sousa, Jorge Henrique Bento de

; Lima, Ian Torres de

; Noronha, Marcos Antonio Neves

; Aranha, Gabriel Lunardi

; Arienzo, Vitor Pelogi

; Lucas, Phellipe Fabbrini Santos

; Steinman, Milton

; Tustumi, Francisco

einstein (São Paulo)

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2023, Volume 21 elocation eAO0204

Abstract: En | Text: En | PDF: En

ABSTRACT Objective To assess the predictive value of preoperative serum laboratory test results for identifying choledocholithiasis and reduce the use of cholangioresonance and its inherent costs. Methods Patients aged 21-69 years who underwent preoperative cholangioresonance examination at our institute were included. Patients with a history of fluctuating jaundice or biliary pancreatitis, bile duct dilatation on ultrasonography, and elevated levels of canalicular enzymes (alkaline phosphatase >100U/L and gamma-glutamyl transferase >50U/L) underwent cholangioresonance-guided surgery. Cases of choledocholithiasis confirmed by cholangioresonance were compared with those without choledocholithiasis. Serum laboratory data were evaluated and the diagnostic capabilities of these examinations were analyzed. Results A total of 104 patients were included. For detecting choledocholithiasis using alkaline phosphatase, the cut-off point was 78U/L, sensitivity was 97.6% (95%CI: 87.4-99.9), and specificity was 72.6% (95%CI: 59.8-83.1). In the binary logistic regression analysis, age (OR= 0.92; 95%CI: 0.86-0.98) and alkaline phosphatase level (OR= 1.02; 95%CI: 1.01-1.05) were selected for the final model. Conclusion Serum alkaline phosphatase levels may aid preoperative diagnosis of asymptomatic choledocholithiasis. After a global clinical assessment of the patient, serum laboratory findings may contribute to a reduction in cholangioresonance-related heathcare costs.

https://doi.org/10.31744/einstein_journal/2023ao0204

10.

Diferenças salariais dos trabalhadores rurais e urbanos dos estados do Amazonas e Pará
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Wendhausen, Enimar Jerônimo

; Brasil, Marília Carvalho

; Alves, Frederick Fagundes

; Sousa, Lucas Vitor de Carvalho

Nova Economia

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2023, Volume 33 N. 3 Pages 659 - 688

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This paper analyses the salary differences between rural and urban workers in the states of Amazonas and Pará. This analysis was conducted for the two largest states in northern Brazil, as they have different socioeconomic and labor market characteristics. Specifically, we examine the extent to which investment in human capital and non-productive attributes affect income differences. We used the Continuous National Household Sample Survey for 2011, 2013, and 2015. We find that highly educated and experienced workers obtain higher wage increases through the fixed-effects pseudo-panel and Oaxaca-Blinder methodologies. Urban workers earn higher wages than rural workers, as well as those residing in the state of Pará. In the state of Amazonas, the wage difference is impacted by non-productive attributes explained by segmentation in the labor market, such as government administration and other activities in contrast to the agricultural sector.

Resumo Este artigo analisa as diferenças salariais entre trabalhadores rurais e urbanos do Amazonas e do Pará. Esta análise foi feita para os dois maiores estados da região Norte por possuírem características socioeconômicas e de mercado de trabalho distintas. Especificamente, verificou-se até que ponto o investimento em capital humano e os atributos não produtivos impactam as diferenças de rendimentos. Utilizou-se a Pesquisa Nacional por Amostra de Domicílios Contínua para 2011, 2013 e 2015. Através das metodologias de pseudopainel com Efeitos Fixos e Oaxaca-Blinder verificou-se que os trabalhadores mais escolarizados e experientes obtêm maiores ganhos salariais. Os trabalhadores urbanos recebem maiores salários do que os trabalhadores rurais, bem como aqueles que residem no Pará. No estado do Amazonas, o que impactou a diferença salarial foram os atributos não produtivos explicados pela segmentação no mercado de trabalho, como a Administração Pública e Outras Atividades em comparação com o setor Agrícola.

https://doi.org/10.1590/0103-6351/7687

11.

Multidisciplinary Scientific Cruises for Environmental Characterization in the Santos Basin – Methods and Sampling Design
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Moreira, Daniel L.

; Dalto, Adriana G.

; Figueiredo JR, Alberto G.

; Valerio, Aline M.

; Detoni, Amalia M. S.

; Bonecker, Ana C. T.

; Signori, Camila N.

; Namiki, Cláudia

; Sasaki, Dalton K.

; Pupo, Daniel V.

; Silva, Danilo A.

; Kutner, Deborah S.

; Duque-Castaño, Diana C.

; Marcon, Eduardo H.

; Gallotta, Fabiana D. C.

; Paula, Fabiana S.

; Gallucci, Fabiane

; Roque, Gabriela C. F.

; Campos, Giulia S.

; Fonseca, Gustavo

; Mattos, Gustavo

; Lavrado, Helena P.

; Silveira, Ilson C. A. da

; Costa, Jessica O.

; Santos Filho, João R. dos

; Carneiro, Juliane C.

; Moreira, Julio C.F.

; Rozo, Laura

; Araujo, Leandro F.M.

; Lazzari, Letícia

; Silva, Letícia O. da

; Michelazzo, Luan S.

; Fernandes, Luciano F.

; Dottori, Marcelo

; Araújo Jr., Marcus A. G. de

; Chuqui, Mateus G.

; Ceccopieri, Milena

; Borges-Silva, Milton

; Kampel, Milton

; Bergo, Natascha M.

; Silva, Paulo V. M.

; Tura, Pedro M.

; Moura, Rafael B. de

; Romano, Renato G.

; Martins, Renato P.

; Carreira, Renato S.

; Toledo, Rodrigo G.A.

; Bonecker, Sérgio L.C.

; Disaró, Sibelle T.

; Rodrigues, Silvana V.

; Corbisier, Thais N.

; Vicente, Thaisa M.

; Paiva, Vitor G. de

; Pellizari, Vivian H.

; Belo, Wellington C.

; Brandini, Frederico P.

; Sousa, Silvia H.M

Ocean and Coastal Research

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2023, Volume 71 Suppl. 3 elocation e23022

Abstract: En | Text: En | PDF: En

Abstract The Santos Basin (SB) is the main petroliferous basin in the Brazilian continental margin and one of the most studied marine areas in Brazil. However, historical data suggest that new efforts should be carried out to acquire quantitative biological data, especially in the deep sea, to establish the baseline of essential ocean variables in different ecosystems for future monitoring programs. The Brazilian energy company Petrobras planned and executed 24 oceanographic cruises over a period of 2 years to assess the benthic (SANSED cruise) and pelagic (SANAGU cruise) systems of the SB (356 days at sea in 2019 and 2021/2022). These efforts were part of the Santos Project, which comprised a comprehensive environmental study aimed at investigating benthic and pelagic variables to characterize ecology, biogeochemistry, thermohaline properties of water masses, and ocean circulation patterns, geomorphology, and sedimentology, as well as organic and inorganic chemistry. Here we present the detailed sampling designs and the field methods employed on board, during the SB scientific cruises. All sampling protocols were based on standardized approaches. For the benthos analyses, triplicate sediment samples were performed using a GOMEX-type box corer (0.25 m²) or a large modified Van Veen grab (0.75 m²) at 100 stations ranging from 25 to 2400 m depth. At each station, 25 geochemical and physico-chemical parameters were analyzed in addition to micro-, meio-, and macrofauna and living foraminifera samples. For the pelagic system, 60 stations were selected to investigate the plankton community, ranging in size from pico- to macroplankton, through vertical, horizontal, and oblique net hauls (20, 200, and 500 μm mesh size), as well as 25 biogeochemical parameters collected with an aid of a CTD-rosette sampler. Part of this scientific information also serves the Regional Environmental Characterization Project (PCR-BS) in support of Petrobras’ Santos Basin drilling licensing process led by the Brazilian Environmental Agency – IBAMA. This project contributes to the sustainable development of the SB, in line with the guidelines of the United Nations Decade of Ocean Science for Sustainable Development.

https://doi.org/10.1590/2675-2824071.22072dlm

12.

VIVÊNCIAS DAS MÃES DE CRIANÇAS CRÔNICAS DEPENDENTES DE TECNOLOGIAS EM UNIDADE DE TERAPIA INTENSIVA PEDIÁTRICA
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Sousa, Brendo Vitor Nogueira

; Silveira, Aline Oliveira

; Oliveira, Elenilda Farias de

; Martins, Gisele

Cogitare Enfermagem

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2023, Volume 28 elocation e88848

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: to describe mothers’ experiences and repercussions of the hospitalization of technology-dependent chronic children in a Pediatric Intensive Care Unit on their personal and family life. Method: qualitative study conducted with 11 mothers of technology-dependent chronic children in a public hospital in the Federal District, Brazil. Data were collected by semi-structured interviews, recorded, later transcribed, coded, and subdivided into categories. Thematic content analysis was used as an analysis strategy. Results: were divided into five categories, which express the experiences of prolonged hospitalization, maternal feelings, difficulties/needs, coping strategies, and context of the pandemic, which highlighted the mostly negative repercussions that bring changes in the family dynamics in general, by needing to reinvent themselves and adapt to the conditions of the child and the hospital. Final considerations: the data show family vulnerability and reinforce the importance of nursing work for the adoption of a family-centered care model.

RESUMEN Objetivo: describir las experiencias de las madres y las repercusiones de la hospitalización de niños crónicos dependientes de tecnología en una Unidad de Cuidados Intensivos Pediátricos en su vida personal y familiar. Método: estudio cualitativo realizado con 11 madres de niños dependientes crónicos de tecnología de un hospital público del Distrito Federal, Brasil. Los datos se recogieron mediante entrevistas semiestructuradas, grabadas, posteriormente transcritas, codificadas y subdivididas en categorías. Se utilizó el análisis de contenido temático como estrategia de análisis. Resultados: se dividieron en cinco categorías, que expresan las experiencias de hospitalización prolongada, los sentimientos maternos, las dificultades/necesidades, las estrategias de afrontamiento y el contexto de la pandemia, que pusieron de relieve las repercusiones, en su mayoría negativas, que provocan cambios en la dinámica familiar en general, ya que tienen que reinventarse y adaptarse a las condiciones del niño y del hospital. Consideraciones finales: los datos muestran la vulnerabilidad familiar y refuerzan la importancia de la actuación enfermera para la adopción de un modelo de atención centrado en la familia.

RESUMO Objetivo: descrever vivências de mães e repercussões da internação de crianças crônicas dependentes de tecnologias em Unidade de Terapia Intensiva Pediátrica na vida pessoal e familiar. Método: estudo qualitativo realizado com 11 mães de crianças crônicas dependentes de tecnologias de um hospital público do Distrito Federal, Brasil. Os dados foram coletados por entrevistas semiestruturadas, gravadas, posteriormente, transcritas, codificadas e subdivididas em categorias. Utilizou-se análise de conteúdo temática como estratégia de análise. Resultados: foram divididos em cinco categorias, que expressam as experiências da hospitalização prolongada, sentimentos maternos, dificuldades/necessidades, estratégias de enfrentamento e contexto da pandemia, que destacaram as repercussões majoritariamente negativas que trazem mudanças na dinâmica familiar de modo geral, ao precisarem se reinventar e se adaptar às condições da criança e do hospital. Considerações finais: os dados evidenciam a vulnerabilidade familiar, e reforçam a importância da atuação da enfermagem para adoção de um modelo de cuidado centrado na família.

https://doi.org/10.1590/ce.v28i0.88848

13.

SATISFAÇÃO COM OS CUIDADOS DE ENFERMAGEM DE PACIENTES ONCOLÓGICOS EM USO DE ANTINEOPLÁSICOS AMBULATORIAL
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Ferreira, Jean Vitor Silva

; Bandeira, Gabriel de Luca Sousa

; Sagica, Tais dos Passos

; Conceição, Crislen de Melo

; Souza, Nathalia Oliveira de

; Costa, Marta Solange Camarinha Ramos

; Ramos, Aline Maria Pereira Cruz

Cogitare Enfermagem

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2023, Volume 28 elocation e90006

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: Evaluate the satisfaction of outpatient oncology users taking antineoplastic drugs about nursing care. Methods: Exsectional study with a quantitative approach, carried out at the Chemotherapy Service of a university hospital located in Belém-PA - Brazil, with 200 users, from June 2019 to June 2022, through interviews and use of the Patient Satisfaction Instrument. Chi-square analysis, Pearson p-value, and chi-square analysis were applied, and the p-value ≤ 0.05 was considered. Results: Users reported good satisfaction in the overall average of the domains (>90%), highlighting the technical-professional domain, followed by the educational and confidence domains. The variables of clarification of medical guidelines, giving good advice, and taking the initiative after patient responses were associated with user satisfaction according to cancer topography and staff availability to those with different degrees of staging. Conclusion: This study assists managers in identifying and planning improvements in areas and services.

RESUMEN Objetivo: evaluar la satisfacción de los usuarios de oncología ambulatoria que utilizan fármacos antineoplásicos sobre los cuidados de enfermería. Métodos: estudio seccional con enfoque cuantitativo, realizado en el Servicio de Quimioterapia de un hospital universitario situado en Belém-PA - Brasilcon 200 usuarios en el período de junio de 2019 a junio de 2022, mediante entrevista y utilización del Instrumento de Satisfacción del Paciente. Se aplicó el análisis chi-cuadrado de Pearson y el valor p ≤0,05. Resultados: los usuarios declararon una buena satisfacción en la media global de los dominios (>90%), destacando el dominio técnico-profesional, seguido de los dominios educativo y de confianza. Las variables de aclaración sobre las directrices médicas, dar buenos consejos, tomar la iniciativa tras las respuestas de los pacientes se asociaron con la satisfacción de los usuarios según la topografía del cáncer y la disponibilidad del personal ante los distintos grados de estadificación. Conclusión: este estudio ayuda a los directivos a identificar y planificar mejoras en áreas y servicios.

RESUMO Objetivo: avaliar a satisfação do usuário oncológico ambulatorial em uso de antineoplásicos sobre os cuidados de enfermagem. Métodos: estudo transversal com abordagem quantitativa, realizado no Serviço de Quimioterapia de um hospital universitário localizado em Belém-PA - Brasil, com 200 usuários no período de junho de 2019 a junho de 2022, através de entrevista e uso do Instrumento de Satisfação do Paciente. Aplicou-se análise de qui-quadrado de Pearson e considerou-se p-valor ≤0,05. Resultados: os usuários relataram bom índice de satisfação na média geral dos domínios (>90%), destacando o domínio técnico-profissional, seguido do educacional e confiança. As variáveis de esclarecimento sobre as orientações médicas, dar bons conselhos, tomar iniciativa após as respostas dos pacientes foram associadas à satisfação do usuário conforme a topografia do câncer e a disponibilidade da equipe àqueles com diferentes graus de estadiamento. Conclusão: este estudo auxilia gestores na identificação e planejamento de melhorias nas áreas e serviços.

https://doi.org/10.1590/ce.v28i0.90006

14.

Interleukin-17 plays a role in dental pulp inflammation mediated by zoledronic acid: a mechanism unrelated to the Th17 immune response?
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CARLOS, Anna Clara Aragão Matos

; LEMOS, José Vitor Mota

; BORGES, Marcela Maria Fontes

; ALBUQUERQUE, Maria Carolina Portela

; SOUSA, Fabrício Bitu

; ALVES, Ana Paula Negreiros Nunes

; DANTAS, Thinali Sousa

; SILVA, Paulo Goberlânio de Barros

Journal of Applied Oral Science

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2023, Volume 31 elocation e20230230

Abstract: En | Text: En | PDF: En

Abstract Objective To evaluate the influence of RORγT inhibition by digoxin on inflammatory changes related to interleukin-17 (IL-17) in the pulp of rats treated with zoledronate (ZOL). Methodology Forty male Wistar rats were divided into a negative control group (NCG) treated with saline solution, a positive control group (PCG) treated with ZOL (0.20 mg/kg), and three groups treated with ZOL and co-treated with digoxin 1, 2, or 4 mg/kg (DG1, 2, and 4). After four intravenous administrations of ZOL or saline solution in a 70-day protocol, the right molars were evaluated by histomorphometry (number of blood vessels, blood vessels/µm2, cells/µm2, total blood vessel area, and average blood vessel area) and immunohistochemistry (IL-17, TNF-α, IL-6, and TGF-β). The Kruskal-Wallis/Dunn test was used for statistical analysis. Results PCG showed an increase in total blood vessel area (p=0.008) and average blood vessel area (p=0.014), and digoxin treatment reversed these changes. DG4 showed a reduction in blood vessels/µm2 (p<0.001). In PCG odontoblasts, there was an increase in IL-17 (p=0.002) and TNF-α (p=0.002) immunostaining, and in DG4, these changes were reversed. Odontoblasts in the digoxin-treated groups also showed an increase in IL-6 immunostaining (p<0.001) and a reduction in TGF-β immunostaining (p=0.002), and all ZOL-treated groups showed an increase in IL-17 (p=0.011) and TNF-α (p=0.017) in non-odontoblasts cells. Conclusion ZOL induces TNF-α- and IL-17-dependent vasodilation and ectasia, and the classical Th17 response activation pathway does not seem to participate in this process.

https://doi.org/10.1590/1678-7757-2023-0230

15.

Characterization of milk production in the mesoregion of central amazon in the state of Amazonas
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Paulo, José Vitor Lima de

; Antonio Neto, Sarquis Monteiro

; Costa, Airton Silva da

; Tonin, Alexandre Alberto

; Sousa, Isadora Karolina Freitas de

; Sousa, Rejane dos Santos

Revista Brasileira de Saúde e Produção Animal

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2023, Volume 24 elocation e20230019

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The objective of this study was to characterize the milk production in the central Amazonian region of the state of Amazonas. A questionnaire, consisting of objective questions, was applied to a sample of 50 properties located in the municipalities of Careiro da Várzea and Itacoatiara. The studied mesoregion develops an extensive dairy cattle breeding, where most of the producers have low schooling (60%), did not receive financing or financial incentive (70%) for the development of the dairy activity, nor are they engaged in associations or cooperatives (96%). Manual milking occurs in 100% of the analyzed properties, only once a day, with only 10% performing hygiene procedures in milking. The average production identified in the region was 3. 5L/cow/day. The uncontrolled natural mount is the only way used in the reproductive management of the properties. The current production is diversified in cattle and bubaline mixed-race (90%). In this region all the owners make use of native pastures. This region develops an extensive dairy cattle ranching, and the efficiency of the production system is limited due to inadequate sanitary, reproductive and food management, which favors low animal productivity.

RESUMO O objetivo deste estudo foi caracterizar a produção leiteira na mesorregião centro amazonense do estado do Amazonas. Foi aplicado um questionário, constituído de questões objetivas, a uma amostra de 50 propriedades localizadas nos municípios de Careiro da Várzea e Itacoatiara. A mesorregião estudada desenvolve uma pecuária leiteira extensiva, onde a maioria dos produtores possui baixa escolaridade (60%), não receberam financiamento ou incentivo financeiro (70%) para o desenvolvimento da atividade leiteira e nem estão engajados em associações ou cooperativas (96%). A ordenha manual do leite ocorre em 100% das propriedades analisadas, uma única vez por dia, sendo que apenas (10%) realiza procedimento de higiene na ordenha. A produção média identificada na região foi de 3,5L/vaca/dia. A monta natural não controlada é a única forma utilizada no manejo reprodutivo das propriedades. A produção atual é diversificada em pecuária de animais bovinos e bubalinos mestiços (90%), nessa mesorregião todos os proprietários fazem uso de pastagens nativas. Essa mesorregião desenvolve uma pecuária leiteira extensiva, sendo a eficiência do sistema de produção limitado em decorrência do inadequado manejo sanitário, reprodutivo e alimentar, o que favorece a baixa produtividade animal.

https://doi.org/10.1590/s1519-994020230019

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