Search | SciELO

ABSTRACT Background: Critical illness is a major ongoing health care burden worldwide and is associated with high mortality rates. Sodium-glucose cotransporter-2 inhibitors have consistently shown benefits in cardiovascular and renal outcomes. The effects of sodium-glucose cotransporter-2 inhibitors in acute illness have not been properly investigated. Methods: DEFENDER is an investigator-initiated, multicenter, randomized, open-label trial designed to evaluate the efficacy and safety of dapagliflozin in 500 adult participants with acute organ dysfunction who are hospitalized in the intensive care unit. Eligible participants will be randomized 1:1 to receive dapagliflozin 10mg plus standard of care for up to 14 days or standard of care alone. The primary outcome is a hierarchical composite of hospital mortality, initiation of kidney replacement therapy, and intensive care unit length of stay, up to 28 days. Safety will be strictly monitored throughout the study. Conclusion: DEFENDER is the first study designed to investigate the use of a sodium-glucose cotransporter-2 inhibitor in general intensive care unit patients with acute organ dysfunction. It will provide relevant information on the use of drugs of this promising class in critically ill patients. ClinicalTrials.gov registry: NCT05558098

RESUMO Antecedentes: A doença crítica é um importante ônus permanente da assistência médica em todo o mundo e está associada a altas taxas de mortalidade. Os inibidores do cotransportador de sódio-glicose do tipo 2 têm demonstrado consistentemente benefícios nos desfechos cardiovasculares e renais. Os efeitos dos inibidores do cotransportador de sódio-glicose do tipo 2 em doenças agudas ainda não foram devidamente investigados. Métodos: O DEFENDER é um estudo de iniciativa do investigador, multicêntrico, randomizado, aberto, desenhado para avaliar a eficácia e a segurança da dapagliflozina em 500 participantes adultos com disfunção orgânica aguda hospitalizados na unidade de terapia intensiva. Os participantes aptos serão randomizados 1:1 para receber 10mg de dapagliflozina e o tratamento padrão por até 14 dias ou apenas o tratamento padrão. O desfecho primário é um composto hierárquico de mortalidade hospitalar, início de terapia renal substitutiva e tempo de internação na unidade de terapia intensiva, até 28 dias. O monitoramento da segurança será rigoroso durante todo o estudo. Conclusão: O DEFENDER é o primeiro estudo desenvolvido para investigar o uso de um inibidor do cotransportador de sódio-glicose do tipo 2 em pacientes de unidade de terapia intensiva geral com disfunção orgânica aguda. O estudo fornecerá informações relevantes sobre o uso de medicamentos dessa classe promissora em pacientes críticos. Registro ClincalTrials.gov: NCT05558098

https://doi.org/10.5935/2965-2774.20230129-en

Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Teixeira, Ricardo Alkmim

; Fagundes, Alexsandro Alves

; Baggio Junior, José Mário

; Oliveira, Júlio César de

; Medeiros, Paulo de Tarso Jorge

; Valdigem, Bruno Pereira

; Teno, Luiz Antônio Castilho

; Silva, Rodrigo Tavares

; Melo, Celso Salgado de

; Elias Neto, Jorge

; Moraes Júnior, Antonio Vitor

; Pedrosa, Anisio Alexandre Andrade

; Porto, Fernando Mello

; Brito Júnior, Hélio Lima de

; Souza, Thiago Gonçalves Schroder e

; Mateos, José Carlos Pachón

; Moraes, Luis Gustavo Belo de

; Forno, Alexander Romeno Janner Dal

; D’Avila, Andre Luiz Buchele

; Cavaco, Diogo Alberto de Magalhães

; Kuniyoshi, Ricardo Ryoshim

; Pimentel, Mauricio

; Camanho, Luiz Eduardo Montenegro

; Saad, Eduardo Benchimol

; Zimerman, Leandro Ioschpe

; Oliveira, Eduardo Bartholomay

; Scanavacca, Mauricio Ibrahim

; Martinelli Filho, Martino

; Lima, Carlos Eduardo Batista de

; Peixoto, Giselle de Lima

; Darrieux, Francisco Carlos da Costa

; Duarte, Jussara de Oliveira Pinheiro

; Galvão Filho, Silas dos Santos

; Costa, Eduardo Rodrigues Bento

; Mateo, Enrique Indalécio Pachón

; Melo, Sissy Lara De

; Rodrigues, Thiago da Rocha

; Rocha, Eduardo Arrais

; Hachul, Denise Tessariol

; Lorga Filho, Adalberto Menezes

; Nishioka, Silvana Angelina D’Orio

; Gadelha, Eduardo Barreto

; Costa, Roberto

; Andrade, Veridiana Silva de

; Torres, Gustavo Gomes

; Oliveira Neto, Nestor Rodrigues de

; Lucchese, Fernando Antonio

; Murad, Henrique

; Wanderley Neto, José

; Brofman, Paulo Roberto Slud

; Almeida, Rui M. S.

; Leal, João Carlos Ferreira

Arquivos Brasileiros de Cardiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 120 N. 1 elocation e20220892

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20220892

Posicionamento sobre Diagnóstico e Tratamento da Amiloidose Cardíaca – 2021
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Simões, Marcus V.

; Fernandes, Fabio

; Marcondes-Braga, Fabiana G.

; Scheinberg, Philip

; Correia, Edileide de Barros

; Rohde, Luis Eduardo P.

; Bacal, Fernando

; Alves, Silvia Marinho Martins

; Mangini, Sandrigo

; Biolo, Andréia

; Beck-da-Silva, Luis

; Szor, Roberta Shcolnik

; Marques Junior, Wilson

; Oliveira, Acary Souza Bulle

; Cruz, Márcia Waddington

; Bueno, Bruno Vaz Kerges

; Hajjar, Ludhmila Abrahão

; Issa, Aurora Felice Castro

; Ramires, Felix José Alvarez

; Coelho Filho, Otavio Rizzi

; Schmidt, André

; Pinto, Ibraim Masciarelli Francisco

; Rochitte, Carlos Eduardo

; Valicelli, Flávio Henrique

; Vieira, Marcelo Luiz Campos

; Mesquita, Cláudio Tinoco

; Ramos, Celso Dario

; Soares-Junior, José

; Romano, Minna Moreira Dias

; Mathias Junior, Wilson

; Garcia Junior, Marcelo Iório

; Montera, Marcelo Westerlund

; Melo, Marcelo Dantas Tavares de

; Silva, Sandra Marques e

; Garibaldi, Pedro Manoel Marques

; Alencar Neto, Aristóteles Comte de

; Lopes, Renato Delascio

; Ávila, Diane Xavier de

; Viana, Denizar

; Saraiva, José Francisco Kerr

; Canesin, Manoel Fernandes

; Oliveira, Glaucia Maria Moraes de

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2021, Volume 117 N. 3 Pages 561 - 598

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20210718 330 downloads

No association between vitamin D status and COVID-19 infection in São Paulo, Brazil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Brandão, Cynthia M. Álvares

; Chiamolera, Maria Izabel

; Biscolla, Rosa Paula Mello

; Lima Junior, José Viana

; Ferrer, Cláudia M De Francischi

; Prieto, Wesley Heleno

; Russo, Pedro de Sá Tavares

; Sá, José de

; Lazari, Carolina dos Santos

; Granato, Celso Francisco H.

; Vieira, José Gilberto H

Archives of Endocrinology and Metabolism

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2021, Volume 65 N. 3 Pages 381 - 385

Abstract: En | Text: En | PDF: En

ABSTRACT In recent years the immunomodulatory actions of vitamin D, a steroid hormone, have been extensively studied. In 2020, due to the COVID-19 pandemic, the question arose as to 25(OH)D status would be related to susceptibility to SARS-CoV-2 infection, since several studies pointed out a higher prevalence and severity of the disease in populations with low levels of 25(OH)D. Thus, we investigated the 25(OH)D levels in adults “Detected” positive for SARS CoV-2 by RT-PCR (reverse transcriptase polymerase chain reaction) test, and in negative controls, “not Detected”, using the Fleury Group's examination database, in Sao Paulo, Brazil. Of a total of 14.692 people with recent assessments of 25(OH)D and RT-PCR tests for COVID-19, 2.345 were positive and 11.585 were negative for the infection. The groups did not differ in the percentage of men and women, or in the age distribution. There were no differences in the distribution of 25(OH)D between the two groups (p = 0.08); mean 25(OH)D of 28.8 ± 21.4 ng/mL and 29.6 ± 18.1 ng/mL, respectively. In the specific population studied, clinical, environmental, socioeconomic and cultural factors should have greater relevance than 25(OH)D in determining the susceptibility to COVID-19.

https://doi.org/10.20945/2359-3997000000343 341 downloads

Does the Plague Still Threaten Us?
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Almeida, Alzira Maria Paiva de

; Sobreira, Marise

; Leal, Nilma Cintra

; Tavares, Celso

Revista da Sociedade Brasileira de Medicina Tropical

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2020, Volume 53 elocation e20190136

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0037-8682-0136-2019 525 downloads

Clinical-histopathological profile of the frontal fibrosing alopecia: a retrospective study of 16 cases of a university hospital
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Secchin, Pedro

; Quintella, Danielle Carvalho

; Paula, Nathalia Ávila de Oliveira

; Andrade, Luana Cristina da Silva

; Sodré, Celso Tavares

Anais Brasileiros de Dermatologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2019, Volume 94 N. 4 Pages 416 - 421

Abstract: En | Text: En | PDF: En

Abstract: Background: Frontal fibrosing alopecia is a condition of unknown origin, histologically similar to classic lichen planopilaris and generally observed in postmenopausal women with alopecia of the frontal-temporal hairline. Objectives: To describe the clinical, dermatoscopic, and histopathological characteristics and the treatment used in patients who have frontal fibrosing alopecia at the Alopecia Outpatient Clinic in a university hospital. Methods: Retrospective descriptive study performed by reviewing medical charts and biopsies of the scalp. Results: Sixteen patients were analyzed, all of them female, 93.75% of them postmenopausal, and 56.25% brown-skinned. All had frontal alopecia (100%), followed by temporal alopecia (87.5%) and madarosis (87.5%). On dermatoscopy, perifollicular erythema and tubular scales were found as a sign of disease activity. Of the patients, 68.75% had associated autoimmune diseases, including lupus, thyroid disease and vitiligo. Of the 13 biopsies from 8 patients, 10 showed microscopic aspects compatible with frontal fibrosing alopecia. Laboratory tests did not show major abnormalities and minoxidil was the most used treatment. Study limitation: Data collection limited by the study’s retrospective design associated to flaws while filling in the medical charts and absence in standards to the collection and processing of the pathology and histopathological examination. Conclusions: A demographical, clinical, and histopathological description of 16 patients diagnosed with frontal fibrosing alopecia, which remains a challenging disease, of unknown origin, and frequently associated with autoimmune diseases. This study reinforces literary findings. However, more research is needed to establish the pathogenesis and effective treatments.

https://doi.org/10.1590/abd1806-4841.20197797 1619 downloads

Analysis of the Ki-67 index in the vaginal epithelium of castrated rats treated with tamoxifen
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Nery-Aguiar, Afif Rieth

; Aguiar, Yousef Qathaf

; Conde Júnior, Airton Mendes

; Alencar, Airlane Pereira

; Tavares, Cleciton Braga

; Lopes-Costa, Pedro Vitor

; Nazário, Afonso Celso

; da Silva, Benedito Borges

Clinics

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2016, Volume 71 N. 2 Pages 90 - 93

Abstract: En | Text: En | PDF: En

OBJECTIVES: Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of tamoxifen on Ki-67 protein expression in the vaginal epithelium of castrated rats. MATERIAL AND METHODS: Forty Wistar-Hannover adult, virgin, castrated rats were randomly divided into two groups, group I (control, n=20) and group II (tamoxifen, n=20), receiving 0.5 ml of propylene glycol and 250 µg of tamoxifen diluted in 0.5 ml of propylene glycol, respectively, daily by gavage for 30 days. On the 31st day, the rats were euthanized and their vaginas were removed and fixed in 10% buffered formalin for the immunohistochemical study of Ki-67 protein expression. Data were analyzed by the Levene and Student’s t tests (p<0.05). RESULTS: The mean index of Ki-67 expression in the rat vagina of groups I and II was 4.04±0.96 and 26.86±2.19, respectively (p<0.001). CONCLUSIONS: According to the results of the present study, tamoxifen, at the dose and treatment length used, induced a significant increase in the cell proliferation of the vaginal mucosa in castrated rats, as evaluated by Ki-67 protein expression.

https://doi.org/10.6061/clinics/2016(02)07 2161 downloads

Plastic surgery in chest wall reconstruction: relevant aspects - case series
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Franco, Diogo

; Tavares Filho, João Medeiros

; Cardoso, Paola

; Moreto Filho, Laércio

; Reis, Mario Celso

; Boasquevisque, Carlos Henrique Ribeiro

; Rocha, Augusto

; Coelho-Oliveira, Afrânio

; Oliveira, José Aldrovando de

; Franco, Talita Romero

Revista do Colégio Brasileiro de Cirurgiões

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2015, Volume 42 N. 6 Pages 366 - 370

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivo: discorrer sobre a participação da Cirurgia Plástica na reconstrução da parede torácica, ressaltando os aspectos relevantes das associações interdisciplinares. Métodos: foram analisados prontuários de 20 pacientes submetidos a extensas ressecções do tegumento torácico, no período entre 2000 e 2014, quanto à indicação das ressecções, à extensão e à profundidade das áreas cruentas, aos tipos de reconstruções realizadas e às complicações. Resultados: entre os 20 pacientes, com média de 55 anos de idade, cinco eram do sexo masculino e 15 do feminino. Foram ressecados: um carcinoma espinocelular, dois carcinomas basocelulares, cinco condrossarcomas e 12 tumores de mama. A extensão das áreas cruentas variou de 4x9 cm até 25x40 cm. Em 12 pacientes as ressecções abrangeram o plano muscular. Nos oito restantes, a retirada do tumor atingiu a espessura total da parede. Para reconstrução foram utilizados: um retalho muscular associado à enxertia de pele, nove retalhos miocutâneos e dez retalhos fasciocutâneos da região. Em dois pacientes submetidos à reconstrução com retalhos fasciocutâneos houve sofrimento parcial do retalho, resolvido com o emprego de retalho miocutâneo. Nos outros pacientes não houve intercorrências com as técnicas empregadas, sendo necessária somente uma cirurgia. Conclusão: a adequada avaliação dos tecidos locais e dos retalhos disponíveis para a reconstrução, além da boa integração da Cirurgia Plástica com as especialidades envolvidas no tratamento, possibilitam extensas ressecções da parede torácica e reconstruções que propiciam a recuperação do paciente.

Objective: to discuss the participation of Plastic Surgery in the reconstruction of the chest wall, highlighting relevant aspects of interdisciplinaryness. Methods: we analyzed charts from 20 patients who underwent extensive resection of the thoracic integument, between 2000 and 2014, recording the indication of resection, the extent and depth of the raw areas, types of reconstructions performed and complications. Results: among the 20 patients, averaging 55 years old, five were males and 15 females. They resections were: one squamous cell carcinoma, two basal cell carcinomas, five chondrosarcomas and 12 breast tumors. The extent of the bloody areas ranged from 4x9 cm to 25x40 cm. In 12 patients the resection included the muscular plane. In the remaining eight, the tumor removal achieved a total wall thickness. For reconstruction we used: one muscular flap associated with skin grafting, nine flaps and ten regional fasciocutaneous flaps. Two patients undergoing reconstruction with fasciocutaneous flaps had partially suffering of the flap, solved with employment of a myocutaneous flap. The other patients displayed no complications with the techniques used, requiring only one surgery. Conclusion: the proper assessment of local tissues and flaps available for reconstruction, in addition to the successful integration of Plastic Surgery with the specialties involved in the treatment, enable extensive resections of the chest wall and reconstructions that provide patient recovery.

https://doi.org/10.1590/0100-69912015006003 7757 downloads

Dermatoscopic fi ndings as a complementary tool in the differential diagnosis of the etiological agent of tinea capitis
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Schechtman, Regina Casz

; Silva, Nanashara Diane Valgas

; Quaresma, Maria Victória

; Bernardes Filho, Fred

; Buçard, Alice Mota

; Sodré, Celso Tavares

Anais Brasileiros de Dermatologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2015, Volume 90 N. 3 Pages 13 - 15

Abstract: En | Text: En | PDF: En

Abstract Tinea capitis is a scalp infection caused by fungi. In Brazil, the main causative agents are Microsporum canis and the Trichophyton tonsurans. Etiological diagnosis is based on suggestive clinical findings and confirmation depends on the fungus growth in culture. However, it is not always possible to perform this test due to lack of availability. We reveal the dermoscopic findings that enable distinction between the main causative agents of Tinea capitis, M. canis and T. tonsurans. The association of clinical and dermatoscopic findings in suspected Tinea capitis cases may help with the differential diagnosis of the etiological agent, making feasible the precocious, specific treatment.

https://doi.org/10.1590/abd1806-4841.20153787 2544 downloads

10.

Alopecia secondary to anti-tumor necrosis factor-alpha therapy
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Ribeiro, Lara Beatriz Prata

; Rego, Juliana Carlos Gonçalves

; Estrada, Bruna Duque

; Bastos, Paula Raso

; Piñeiro Maceira, Juan Manuel

; Sodré, Celso Tavares

Anais Brasileiros de Dermatologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2015, Volume 90 N. 2 Pages 232 - 235

Abstract: En | Text: En | PDF: En

Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti-TNF). Psoriasiform cutaneous reactions and few cases of alopecia can occur in some patients while taking these drugs. Two cases of alopecia were reported after anti-TNF therapy. Both also developed psoriasiform lesions on the body. This is the second report about a new entity described as 'anti-TNF therapy-related alopecia', which combines clinical and histopathological features of both alopecia areata and psoriatic alopecia. The recognition of these effects by specialists is essential for the proper management and guidance of these patients.

https://doi.org/10.1590/abd1806-4841.20153084 2440 downloads

11.

Seroprevalence of hantavirus and Yersinia pestis antibodies in professionals from the Plague Control Program
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Costa, Erika de Cassia Vieira da

; Chioratto, Gerlane Tavares de Souza

; Guarana, Paulo Thiago Melo

; Sobreira, Marise

; Aragao, Ivoneida

; Silva, Robervaldo

; Rocha, Sheila Sotelino

; Tavares, Celso

; Almeida, Alzira Maria Paiva de

Revista da Sociedade Brasileira de Medicina Tropical

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jul 2013, Volume 46 N. 4 Pages 490 - 492

Abstract: En | Text: En | PDF: En

Introduction Professionals who handle rodents in the field and in the laboratory are at risk of infection by the microorganisms harbored by these animals. Methods Serum samples from professionals involved in rodent and Yersinia pestis handling in field or laboratory work were analyzed to determine hantavirus and plague seroprevalence and to establish a relationship between these activities and reports of illnesses. Results Two individuals had antibodies against hantavirus, and two harbored antibodies against the plague; none of the individuals had experienced an illness related to their duties. Conclusions These results confirm the risks of hantavirus- and plague-related field and laboratory activities and the importance of protective measures for such work.

https://doi.org/10.1590/0037-8682-1394-2013 1788 downloads

12.

Follicular red dots: a normal trichoscopy feature in patients with pigmentary disorders?
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Pirmez, Rodrigo

; Pineiro-Maceira, Juan

; Almeida, Barbara Cristina Rodrigues de

; Sodre, Celso Tavares

Anais Brasileiros de Dermatologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2013, Volume 88 N. 3 Pages 459 - 461

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Pontos vermelhos foliculares foram descritos como achado tricoscópico de lupus eritematoso discóide do couro cabeludo em atividade e a presença destes associado a melhor prognóstico. Relatamos cinco pacientes com distúrbios da pigmentação nos quais pontos vermelhos foliculares foram detectados ao exame do couro cabeludo. Sugerimos que este padrão está provavelmente relacionado à rica vascularização que naturalmente envolve o folículo piloso normal. As possíveis implicações desta suposição nos casos de lupus eritematoso discóide e outras doenças do couro cabeludo também são discutidas.

Follicular red dots have been described as a trichoscopic feature of active discoid lupus erythematosus of the scalp and its presence associated with a better prognosis. We report five patients with pigmentary disorders in whom follicular red dots were detected during scalp examination. We suggest that this pattern is probably related to the rich vasculature that naturally envelops the normal hair follicle. The possible implications of such proposition in cases of discoid lupus erythematosus and other scalp disorders are also discussed.

https://doi.org/10.1590/abd1806-4841.20132555 2666 downloads Cited 1 time in SciELO

13.

Preocupação e insatisfação com o corpo, checagem e evitação corporal em pessoas com transtornos alimentares
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Campana, Angela Nogueira Neves Betanho

; Tavares, Maria da Consolação Gomes Cunha Fernandes

; Garcia Júnior, Celso

Paidéia (Ribeirão Preto)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2012, Volume 22 N. 53 Pages 375 - 381

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Este estudo teve por objetivo avaliar aspectos da imagem corporal em uma amostra de pessoas com anorexia nervosa, bulimia nervosa e transtorno alimentar não-especificado. A amostra foi composta por 14 voluntárias atendidas pelo Ambulatório de Transtornos Alimentares da Universidade Estadual de Campinas. O Software de Avaliação Perceptiva foi utilizado para avaliar a insatisfação com o corpo. A preocupação com o corpo, checagem e evitação corporal foram avaliadas pelo Body Shape Questionnaire, Body Checking Questionnaire e Body Image Avoidance Questionnaire, respectivamente. A análise descritiva e as correlações entre as medidas mostraram elevados níveis de insatisfação, checagem, evitação e preocupação com o corpo, com associações significantes. Estes achados evidenciaram a importância dos parâmetros investigados na dinâmica dos transtornos alimentares. Conhecer esses componentes da imagem corporal favorece a ampliação das possibilidades de melhor compreender como se organiza a representação mental do corpo dessas pacientes e planejar mais cuidadosamente as intervenções no decurso do tratamento.

The aim of this study was to investigate aspects of body image in a sample of people with anorexia nervosa, bulimia nervosa and eating disorder not otherwise specified. The sample was composed of 14 volunteers, cared for by the Eating Disorders Outpatients Clinic, from Universidade Estadual de Campinas. The Software for Perceptual Assessment (SPA) assesses body dissatisfaction. The variables body concern, checking behavior and avoidance behavior were assessed by the Body Shape Questionnaire, Body Checking Questionnaire and Body Image Avoidance Questionnaire, in this order. The descriptive analysis and correlations indicate high levels of dissatisfaction, checking behavior, avoidance behavior, and concern over the body, with significant associations. These findings showed the importance of the investigated parameters for the dynamic of the disease. Knowing these body image components could expand the possibilities of understanding how these patients organize their body representations and carefully plan interventions during the course of the treatment.

El objetivo de este estudio fue investigar los aspectos del imagen corporal en una muestra de personas con anorexia nerviosa, bulimia nerviosa y trastorno alimenticio no especificado. La muestra estuvo compuesta por catorce voluntarios, atendidos por la Clínica de Trastornos Alimenticios de la Universidade Estadual de Campinas, Brasil. Se utilizó el Software de Avaliação Perceptiva para evaluar la insatisfacción corporal. Las variables preocupación con cuerpo, control y conducta de evitación fueron evaluadas con el Body Shape Questionnaire, Body Checking Questionnaire y Body Image Avoidance Questionnaire, en esta orden. El análisis descriptivo y las correlaciones mostraron altos niveles de insatisfacción, conducta de evitación y control, preocupación con el cuerpo, con asociaciones significativas. Estos resultados demuestran la importancia de los parámetros investigados en la dinámica de la enfermedad. Conocer estos componentes del imagen corporal podría aumentar las posibilidades de la comprensión de cómo la representación del cuerpo se organiza para estos pacientes y planificar cuidadosamente las intervenciones en el curso del tratamiento.

14133 downloads Cited 1 time in SciELO

14.

Avanços nos materiais e no tratamento endovascular de oclusões arteriais crônicas totais: um relato de caso
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Neves, Daniel Queiroz

; Cunha Junior, Jorge Ribeiro da

; Cardoso, Márcio Cerbazzi Tavares

; Lima, Mauro Henrique de

; Solano, Gustavo Petorossi

; Chouin, Celso Luis Muhlethaler

; Azevedo, Sérgio Lopes de

; Reis, Paulo Eduardo Ocke

Jornal Vascular Brasileiro

Journal Metrics
- Sobre o periódico
- SciELO Analytics

sep 2012, Volume 11 N. 3 Pages 226 - 231

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

As oclusões arteriais crônicas totais com forte componente cálcico são ainda nos dias atuais, um fator muitas vezes limitante para o tratamento endovascular devido à dificuldade em transpor estas lesões com fios-guia e cateteres habitualmente utilizados. Revisamos a literatura e descrevemos um caso de tratamento endovascular de uma oclusão total de artéria ilíaca externa, onde o uso de novos materiais desenvolvidos especificamente para o tratamento deste tipo de lesão foi determinante para o sucesso do caso.

Chronic arterial occlusions with great calcium component are usually a factor of limitation to endovascular treatment to the difficulty to transpose these lesions with guidewires and catheters commonly used. We reviewed the literature and described a case of endovascular treatment of a total occlusion of external iliac artery, where the use of new materials developed specifically to the treatment of such injuries was critical to the success of the case.

3172 downloads

15.

Envolvimento tímico na imunoterapia específica e na alergia respiratória a Dermatophagoides teronyssinus
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Pereira, Celso

; Loureiro, Graça

; Martinho, António

; Paiva, Artur

; Tavares, Beatriz

; Machado, Daniel

; Nunes, Rodrigo

; Pedreira, Susana

; Pais, Maria Luísa

; Segorbe-Luís, António

Revista Portuguesa de Imunoalergologia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jan 2012, Volume 20 N. 1 Pages 33 - 46

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Introdução:Os círculos de excisão do receptor da célula T (TRECs) em linfócitos T -CD31+ correlacionam-se com células recentemente emigradas do timo (RTEs). Objectivo: Avaliar o efeito da SIT no número de TRECs presentes em linfócitos T periféricos em doentes alérgicos a Dermatophagoides pteronyssinus (Dpt), bem como os efeitos decorrentes da resposta alérgica específica. Metodologia: Foram estudados 85 doentes com alergia respiratória a Dpt: 41 doentes (Grupo II) em SIT de manutenção (21 por via sublingual; 20 por via subcutânea); 44 doentes (Grupo I), sem terapêutica específica, sendo que 22 deles foram submetidos a prova de provocação específica (nasal=22; conjuntival=22). Todos foram submetidos a estudo de celularidade basal no dia do estudo. Após administração do extracto terapêutico ou da solução alergénica procedeu-se a novo estudo aos 60 ou 240 minutos. Foi quantificado o número de TRECs presentes em células CD4+CD31+ e CD8+CD31+ e os resultados expressos por 100 000 células. Amostras de 10 indivíduos saudáveis (Grupo III) foram analisadas nos mesmos tempos. Resultados: O valor de TRECs em RTEs foi constante no grupo controlo. Nos doentes do Grupo I a quantificação de TRECs em células CD4+CD31+ apresentaram diferenças intra-individuais relativamente ao valor basal, estatisticamente significativo aos 240 minutos. Nos doentes do Grupo II observou-se, também, marcada variabilidade intra-individual, independentemente da via de administração. Os valores basais obtidos no Grupo III foram significativamente superiores aos obtidos na determinação basal dos restantes grupos. Conclusões: A actividade funcional tímica está precocemente envolvida na resposta alérgica e na SIT. A exposição a alergénios determina, precocemente, a presença de RTEs na periferia, particularmente do fenótipo CD4+CD31+/TRECs. Nos doentes submetidos a SIT, a redução de RTEs circulantes poderá resultar da necessidade de maturação e diferenciação linfocitária. Estes resultados sugerem um envolvimento do tecido funcional tímico nos mecanismos centrais da alergia e da SIT.

Introduction: T cell receptor excision circles (TRECs) on CD31+ T cells are related to recent thymic emigrant cells (RTEs).Aim: Evaluation of specific immunotherapy effects on number of TREC in peripheral T cells in patients allergic to Dermatophagoides pteronyssinus (Dpt). Method: 85 respiratory allergic patients (both genders), 41 (Group II) under maintenance treatment to Dpt SIT (21 sublingual, SLIT, and 20 subcutaneous, SCIT), were selected. The allergic patients (Group I) without specific treatment underwent an allergen challenge test (22 nasal and 22 conjunctival). Peripheral cell analysis was performed immediately before treatment and 60 or 240 minutes after allergenic extract administration. TREC count was performed in CD4+CD31+ and CD8+CD31+ cells. The results were expressed per 100,000 RTE-related cells. Samples from 10 healthy individuals (Control - Group III) were obtained using the same method. Results: The value of TRECs on RTEs was constant in control groups. Group I patients’ TREC count in CD31+-T cells showed relevant individual changes, even in the patients tested earlier (60 minutes), and statistical significant at 240 minutes. Both SCIT and SLIT also demonstrated enormous individualchanges, particularly on TRECs/CD4+CD31+ cell assay. Basal values in Group III were significantly higher than those observed in active patient groups. Conclusions: Thymic functional activity has early involvement in the allergic reaction and SIT. IgEmediated allergy is able to induce RTEs in the periphery, particularly TRECs/CD4+CD31+ cells. Both SLIT and SCIT showed reduced RETs in the periphery, probably due to maturation of regulatory T cells. Our results suggest a crucial role of the functional thymic tissue in the central mechanism of this therapy.

1398 downloads

Showing

itens per page

Page of 3 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »