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Resumen El síndrome de persona rígida es un cuadro neuro lógico infrecuente caracterizado por rigidez muscular de tronco y extremidades y espasmos musculares ga tillados por estímulos sensoriales o emocionales, que progresa hacia la postración. Cuenta con un mecanismo fisiopatogénico con base inmunológica, en el cual los autoanticuerpos, como el antiGAD65, cumplen un rol central. Asimismo, la detección de dichos anticuerpos corrobora el diagnóstico ante un paciente con cuadro clínico sugestivo. Un 4 a 6% de los casos tienen neoplasias subyacentes. El tratamiento se basa en el manejo sintomático, inmunomodulador y de la enfermedad de base en los casos paraneoplásicos. Reportamos un caso de síndrome de persona rígida clásico asociado a timoma y describimos las características principales de esta entidad.

Abstract Stiff-person syndrome is a rare neurological condi tion characterized by muscular rigidity of the trunk and extremities and muscle spasms triggered by sensory or emotional stimuli, which progresses towards prostra tion. It has a pathophysiogenic mechanism with an immunological basis, in which autoantibodies, such as antiGAD65, play a central role. Likewise, the detec tion of these antibodies corroborates the diagnosis in a patient with a suggestive clinical picture. Four to 6% of cases have underlying neoplasms. Treatment is based on symptomatic, immunomodulatory, and underlying disease management in paraneoplastic cases. We re port a case of classic stiff person syndrome associated with thymoma and review the main characteristics of this entity.

Condiciones laborales y extralaborales relacionadas con la presencia de síntomas depresivos en mujeres trabajadoras con empleos de subsistencia en el centro de Medellín, 2015-2019
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Garzón-Duque, María Osley

; Uribe-Cárdenas, Paula Andrea

; Rodríguez-Ospina, Fabio León

; Cardona-Arango, Doris

; Segura-Cardona, Angela María

; Marulanda-Henao, Sara

Revista Colombiana de Psiquiatría

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dec 2022, Volume 51 N. 4 Pages 281 - 292

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Objetivo: Determinar las condiciones laborales y extralaborales relacionadas con los síntomas depresivos de trabajadoras informales del centro de Medellín en 2015-2019. Métodos: Estudio transversal con intención analítica y fuentes primarias de información. Toma de datos con encuesta asistida en una de sus sedes gremiales en 2016, después de prueba piloto y estandarización de encuestadores. Se tomó por censo a 291 trabajadoras y se exploraron sus características laborales y extralaborales. Resultados: Las mujeres tenían una media de edad de 45 arios, escolaridad < 5 años, viviendas en estrato bajo y medio e ingresos inferiores al salario mínimo de 2016. Alrededor del 60,0% tenía inseguridad alimentaria moderada-grave, sin subsidio del Estado; eran fundamentalmente cabezas de familia, con 2 o menos personas a su cargo, y responsables de sus labores en el hogar. Laboraban al menos 8h al día 6 o 7 días a la semana, con padres o parientes venteros, y al menos 20 años en su labor. Alrededor del 60,0% tenía pareja, el 21,6% con disfuncionalidad familiar, y el 15,4% sufría síntomas depresivos moderados-graves (MG). Se asociaron y aportaron a la explicación de síntomas depresivos MG, vivir en cuarto o inquilinato, en estrato socioeconómico bajo y tener disfuncionalidad familiar MG. Conclusiones: Las condiciones extralaborales que se asocian y explican los síntomas depresivos MG de las trabajadoras pueden modificarse con acciones que impacten en los determinantes sociales de la salud.

ABSTRACT Objective: To determine the working and non-working conditions related to depressive symptoms in informal workers in the centre of Medellín in 2015-2019. Methods: Cross-sectional study with analytical intention and primary sources of information. Data collection with assisted survey in one of its union headquarters in 2016, after a pilot test and standardisation of pollsters. A total of 291 women workers were taken as a census, and their working and non-working conditions were explored. Results: The women had an average age of 45 years, <5 years of schooling, low and middle-income housing, and income below the 2016 minimum wage. About 60% suffered moderate-severe food insecurity, and received no state benefits. They were mainly the head of the family, with 1 or 2 dependents, and were responsible for the work at home. They worked at least 8 hours a day, 6 or 7 days a week, with parents or relatives selling in the street, and at least 20 years in their work. About 60% had a partner, 21.6% with family dysfunction, and 15.4% moderate-severe depressive symptoms. Living in one room or a slum, with a low socioeconomic status and moderate-severe family dysfunction were associated with, and contributed to the explanation of, moderate-severe depressive symptoms. Conclusions: The non-working conditions that are associated with and explain the moderate-severe depressive symptoms of female workers can be modified with actions that impact on the social determinants of health.

https://doi.org/10.1016/j.rcp.2020.11.013

Embarazo en la adolescencia: diseño y validación de un instrumento para medir el trabajo intersectorial
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Rincón-Méndez, Alba Yaneth

; Hernández-Sánchez, Jacqueline

; Niño-Bautista, Lucila

; Camargo-Figuera, Fabio Alberto

; Mantilla-Uribe, Blanca Patricia

Hacia la Promoción de la Salud

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dec 2022, Volume 27 N. 2 Pages 21 - 36

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen El trabajo intersectorial en la promoción de la salud es ampliamente reconocido; sin embargo, la literatura consultada evidenció ausencia de instrumentos válidos y confiables en esta área. Objetivo: diseñar y validar un instrumento para medir el trabajo intersectorial en funcionarios públicos que participaron en una Estrategia Nacional de Prevención del Embarazo en la Adolescencia (EPEA). Metodología: 1. Diseño del instrumento a partir de revisión de literatura, antecedentes de trabajo intersectorial en Colombia y experiencia del equipo investigador; 2. Validación facial para medir precisión, pertinencia, claridad y comprensión de los ítems con muestra por conveniencia de 12 personas; 3. Validación del constructo mediante modelo Rasch, sobre muestra de 132 funcionarios públicos. Resultados: el instrumento final conformado por 21 ítems, presentó buenas propiedades de validez facial y de constructo. La consistencia interna fue de 0,92; en el análisis Rasch se excluyeron personas e ítems que no se ajustaron al modelo, logrando correlaciones positivas entre ítems y medidas mayores a 0,47, unidimensionalidad con una varianza explicada por las medidas de 44,6 %; la varianza explicada en el primer contraste de los residuales fue de 5,7 %, la separación de personas fue de 2,07 y de ítems de 4,51 y la dificultad de los ítems estuvo entre -3,14 y 3,69 lógitos. Ninguno de los ítems presentó funcionamiento diferencial. Conclusiones: se cuenta con un instrumento válido y confiable con 21 ítems para la evaluación de competencias en trabajo intersectorial de funcionarios públicos que trabajan en prevención del embarazo en la adolescencia.

Resumo O trabalho intersetorial na promoção da saúde é amplamente reconhecido; porém, a literatura consultada evidenciou ausência de instrumentos válidos e confiáveis nesta área. Objetivo: desenhar e validar um instrumento para medir o trabalho intersetorial em funcionários públicos que participaram em uma Estratégia Nacional de Prevenção da Gravidez na Adolescência (EPEA). Metodologia: 1. Desenho do instrumento a partir de revisão de literatura, antecedentes de trabalho intersetorial na Colômbia e experiência da equipe investigador; 2. Validação facial para medir precisão, pertinência, claridade e compreensão dos itens com amostra por conveniência de 12 pessoas; 3. Validação do constructo mediante modelo Rasch, sobre amostra de 132 funcionários públicos. Resultados: o instrumento final conformado por 21 itens, apresentou boas propriedades de validez facial e de constructo. A consistência interna foi de 0,92; na análise Rasch se excluíram pessoas e itens que não se ajustaram ao modelo, logrando correlações positivas entre itens e medidas maiores a 0,47, unidimensionalidade com uma variância explicada pelas medidas de 44,6 %; a variância explicada no primer contraste dos residuais foi de 5,7 %, a separação de pessoas foi de 2,07 e de itens de 4,51 e a dificuldade dos itens esteve entre -3,14 e 3,69 lógitos. Nenhum dos itens apresentou funcionamento diferencial. Conclusões: conta-se com um instrumento válido e confiável com 21 itens para a avaliação de competências em trabalho intersetorial de funcionários públicos que trabalham em prevenção da gravidez na adolescência.

Abstract Even though intersectoral work in health promotion is widely recognized, the literature consulted showed an absence of valid and reliable instruments in this area. Objective: to design and validate an instrument to measure intersectoral work in public officials who participated in a National Strategy for the Prevention of Pregnancy in Adolescence (EPEA in Spanish). Materials and methods: 1. Design of the instrument based on a literature review, history of intersectoral work in Colombia and experience of the research team; 2. Facial validation to measure precision, relevance, clarity and understanding of the items with a convenience sample of 12 people; 3. Validation of the construct using the Rasch model, on a sample of 132 public officials. Results: The final instrument, made up of 21 Items, presented good facial and construct validity properties. The internal consistency was 0.92. In the Rasch analysis, people and items that did not fit the model were excluded, achieving positive correlations between items and linearity measures greater than 0.47 with a variance explained by the measures of 44.6%. The variance explained in the first contrast of the residuals was 5.7%, the separation of people was 2.07 and of items was 4.51 and the difficulty of the items was between -3.14 and 3.69 logits. None of the items presented differential functioning. Conclusions: there is a valid and reliable instrument with 21 items, for the evaluation of competencies in intersectoral work of public officials who work in prevention of pregnancy in adolescence.

https://doi.org/10.17151/hpsal.2022.27.2.3 18 downloads

The effects of Transcranial Direct Current Stimulation on psychomotor performance of athletes: a systematic review and meta-analysis
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Alves-Lobão, Thais

; Sarmiento-Rivera, Luis Felipe

; Vale, Flavia Beatriz Xavier

; Campos, Yan Sobral

; Rincon-Uribe, Fabio Alexis

; Godinho, Rejane Célia de Souza

; Campos, Italo Sergio Lopes

; Pedroso, Janari da Silva

; Junior, Amauri

Motricidade

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sep 2022, Volume 18 N. 3 Pages 458 - 466

Abstract: En | Text: En | PDF: En

ABSTRACT Psychomotor performance is a complex function generated by brain and motor systems integration, measured by accuracy, latency, and movement speed. In sports, looking for ways to improve movements is usual. Also, utilising Transcranial Direct Current Stimulation (tDCS) as a non-invasive stimulation technique may produce alterations in psychomotor sports skills. We conducted a systematic review, including experimental studies with sham or control groups in adults reporting tDCS effects on athletes’ psychomotor performance. Cochrane Manual for Systematic Reviews and the statement on systematic reviews and meta-analysis of PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols) were followed. PsycINFO, PubMed (central), Scopus, Web of Science, Embase, SPORTDiscus, and Cochrane Library databases were searched. Empirical studies published in English, Spanish, and Portuguese from 2009 onwards and whose primary results presented an effective measure of transcranial direct current stimulation in the psychomotor performance of adult athletes were included. The results list 10 articles, 6 of them entered in the meta-analyses. The articles presented a low risk of bias and low publication bias but great dispersion of stimulation areas.

https://doi.org/10.6063/motricidade.26513

Patient with an implantable cardiac electrical stimulation device. What should the anesthesiologist know?
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Sepúlveda-López, Fabio Alejandro

; Jiménez-Muñoz, Luz María

; Agudelo-Uribe, Juan Fernando

; Castro-Pérez, Jorge Alberto

Colombian Journal of Anestesiology

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dec 2021, Volume 49 N. 4 elocation e301

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen El paciente portador de un dispositivo de estimulación eléctrica cardiaca implantable se convierte en un reto para el anestesiólogo debido a que implica un conocimiento integral que abarca su funcionamiento, las indicaciones que llevaron a su implante y las implicaciones que se deben abordar en el perioperatorio. Este artículo busca proporcionar al lector información clara y estructurada que le permita al anestesiólogo enfrentarse de forma segura al escenario de un paciente con un dispositivo de estimulación eléctrica cardiaca implantable programado para cirugía emergente. Se realizó una búsqueda de la evidencia científica disponible en bases de datos (Pubmed / Medline, ScienceDirect, OVID, SciELO), para una revisión no sistemática. La incidencia en el uso de dispositivos de estimulación eléctrica cardiaca viene en aumento. Su funcionamiento es cada vez más complejo lo cual implica una actualización permanente del conocimiento en esta área.

Abstract Patients with implantable electric stimulation devices are challenging to the anesthesiologist since these cases demand a comprehensive knowledge about how the device operates, the indications for the implant and the implications that must be addressed during the perioperative period. This article is intended to provide the reader with clear and structured information so that the anesthesiologist will be able to safely deal with the situation of a patient with an implantable cardiac stimulation device, who has been programmed for emergent surgery. A search for the scientific evidence available was conducted in Pubmed / Medline, ScienceDirect, OVID, SciELO), for a non-systematic review. The incidence of the use of cardiac electric stimulation devices has been growing. Their operation is increasingly complex, and demands being constantly updated on the knowledge in the area.

https://doi.org/10.5554/22562087.e976 243 downloads

Mortalidad y desenlaces clínicos en pacientes críticamente enfermos con infecciones por bacterias productoras de carbapenemasas en un hospital de alta complejidad en Bogotá, Colombia
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Varón, Fabio Andres

; Uribe, Ana Maria

; Palacios, Jonathan Orlando

; Sánchez, Efraín Guillermo

; Gutiérrez, Deimer

; Carvajal, Katherine

; Cardona, Santiago

; Noreña, Ivan Enrique

Infectio

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mar 2021, Volume 25 N. 1 Pages 16 - 21

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: Los microorganismos capaces de producir carbapenemasas vienen incrementándose a nivel mundial y se han convertido en un problema de salud pública global. En Colombia actualmente la resistencia a carbapenémicos en las unidades de cuidado intensivo está aumentando y se desconoce su impacto en desenlaces clínicos. Objetivos: Determinar las características demográficas, clínicas, y los desenlaces de los pacientes adultos en estado crítico con infección por microorganismos productores de carbapenemasas en una unidad de cuidado intensivo polivalente de una institución de alta complejidad. Métodos: Estudio observacional, descriptivo y retrospectivo, incluyendo pacientes con infección por bacterias resistentes a carbapenémicos, ingresados a la unidad de cuidado intensivo entre el 1 de Enero de 2014 y el 1 de Enero de 2018. Se excluyeron los pacientes colonizados. Se evaluaron complicaciones clínicas, estancia en UCI y hospitalaria, así como la mortalidad en UCI y hospitalaria. Resultados: Se incluyó 58 pacientes. La mortalidad global fue de 67,2%, de los cuales 55,17% murió durante su estancia en la unidad de cuidado intensivo y 12.06% en hospitalización. La mediana de estancia en la unidad de cuidado intensivo fue de 18 días (RIQ 4-28). La causa más frecuente de mortalidad fue choque séptico en 51% y las complicaciones más comunes fueron lesión renal aguda y delirium en un 55,2% y 43,1%, respectivamente. La mediana de estancia en la UCI fue de 18 días (RIQ 4-28). Conclusiones: Las infecciones por bacterias resistentes a carbapenémicos en pacientes críticamente enfermos se relacionan con altas tasas de mortalidad, complicaciones y estancia prolongada en UCI

Abstract Introduction: Microorganisms able to produce carbapenemases are spreading worldwide and have become a concerning global public-health problem. In Colombia, the Gram-negative resistance to carbapenems at intensive care units is currently increasing and its impact on clinical outcomes is not well known. Objectives: To determine the demographic, clinical characteristics and outcomes of critically ill adult patients with infection by carbapenemase producing bacteria in a polyvalent intensive care unit of a highly complex institution. Methods: Single-center retrospective, descriptive observational study including critically ill adult patients infected by carbapenemase-producing bacteria and transferred to a polyvalent intensive care unit from January 1th 2014 to January 1th 2018. Known colonized patients were excluded. Clinical complications, ICU and in-hospital days of stay were evaluated, as ICU and in-hospital mortality. Results: A total of 58 patients were included. Overall mortality was 67.2%, of which 55.17% died during their stay in the intensive care unit and 12.06% in hospitalization. The median stay in the intensive care unit was 18 days (IQR 4-28). The most frequent cause of death was septic shock in 51% and the most common complications were acute renal injury and delirium in 55.2% and 43.1%, respectively. The median stay in the ICU was 18 days (RIQ 4-28). Conclusions: Infections caused by carbapenem-resistant bacteria in critically ill patients are associated with high mortality rates, complications and long stay in ICU.

https://doi.org/10.22354/in.v25i1.903 416 downloads

A propósito de complicaciones infrecuentes de enfermedades comunes. Síndrome de Ekiri
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Varón Vega, Fabio Andrés

; Uribe Hernández, Ana María

; Buitrago-Toro, Kenny

Infectio

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mar 2021, Volume 25 N. 1 Pages 67 - 70

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La infección por enterobacterias desencadena usualmente síntomas gastrointestinales caracterizados por vómito, diarrea y dolor abdominal, de severidad y curso variable. El compromiso extraintestinal esta descrito, inclusive sin las manifestaciones gastrointestinales clásicas lo que favorece diagnósticos y tratamientos tardíos pudiendo llegar a ser incapacitantes y letales. El síndrome de Ekiri, también denominado síndrome de encefalopatía letal tóxico, se caracteriza por una disfunción aguda del sistema nervioso central secundaria a infección por enterobacterias las cuales favorecen el desarrollo de microtrombos a nivel cerebral con inflamación mediada por el factor de necrosis tumoral α e IL- 1β y disfunción de la barrera hematoencefálica con una alta tasa de mortalidad. Dentro de nuestro conocimiento, presentamos el primer caso reportado en Colombia sobre el síndrome de Ekiri.

Abstract Gastrointestinal infection usually manifests with nausea, vomit and abdominal pain, all of them wit course and variable severity. Extrainstestinal compromise is described, even without gastrointestinal symptoms, what causes a delay on diagnosis and treatment, worsening the prognosis. Ekiri syndrome, also known as lethal toxic encephalopathy is characterized by an acute neurological dysfunction secondary to enterobacterial infection which favor thrombi development and local inflammation mediated by tumor necrosis factor alpha and IL-1β with blood brain barrier dysfunction and high mortality. As we know, we present the first Ekiri syndrome case reported in Colombia.

https://doi.org/10.22354/in.v25i1.913 377 downloads

Association between the dispositional optimism and depression in young people: a systematic review and meta-analysis
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Uribe, Fabio Alexis Rincón

; Oliveira, Silvia Botelho de

; Gouveia Junior, Amauri

; Pedroso, Janari da Silva

Psicologia: Reflexão e Crítica

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2021, Volume 34 elocation 37

Abstract: En | Text: En | PDF: En

Abstract The objective of this study was to perform a meta-analysis of publications that reported the association between dispositional optimism and depression during youth, analyzing if the strength of this relationship varied according to potential factors. Systematic searches were carried out in APA PsycNet, Virtual Health Library, Embase, Web of Science, PubMed Central, and Scopus to collect English, Portuguese, or Spanish studies from 2009 onwards. Two reviewers selected the eligible articles, assessed the quality of each study, and extracted the data. For the synthesis of the results, a meta-analytic approach was used. We identified 4077 publications in the initial searches and 22 in the supplementary searches, from which 31 studies remained for analysis once the eligibility criteria were applied. The results showed a statistically significant negative association between dispositional optimism and depression in the young population, age being a factor that modifies the effect measure between these variables. This meta-analysis provides a consistent and robust synthesis on the interaction effect between dispositional optimism and depression in the young population. Based on these findings, early clinical admissions may effectively improve optimistic tendencies in young people, which could help them prevent depressive symptoms or episodes.

https://doi.org/10.1186/s41155-021-00202-y

Multimorbilidad en adultos mayores con empleos con subsistencia en las calles y aceras de Medellín, Colombia, 2016
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Garzón Duque, María Osley

; Toro Rivera, José Alejandro

; Rodríguez Ospina, Fabio León

; Cardona Arango, Doris

; Segura Cardona, Ángela María

; Uribe Cárdenas, Paula Andrea

; Martínez Romero, María Camila

Revista de la Asociación Española de Especialistas en Medicina del Trabajo

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2021, Volume 30 N. 4 Pages 475 - 494

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Objective: To determine the working conditions, habits and lifestyles related to the multimorbidity of older adults with subsistence jobs in the center of Medellín-Colombia, 2016. Material and Methods: Cross-sectional study with primary sources of information to a census of 686 workers, surveyed After obtaining informed consent, in 2016. For this study, 153 workers aged ≥60 years were taken. Univariate, bivariate and multivariate analysis, to study their multimorbidity and factors associated with their work. Results: 77,0% were between 60-69 years old; mainly men, 56,0% earned <500,000 Colombian pesos. They were > 20 years old in their trade. 62,0% presented multimorbidity, mainly due to diabetes; hypertension; obesity and depressive symptoms. They explained a higher prevalence of multimorbidity (p<0,05) working near wastewater (RPA=3,38.CI=1,27; 8,96), not having a schedule for food consumption (RPA=3,01.CI=1,25;7,27) and consuming food alone (RPA=3,28.CI=1,31; 8,18). Conclusion: The conditions that explain multimorbidity in these workers can be reversed with health promotion and disease prevention actions, led by the State and with its active participation.

RESUMEN Objetivo: Determinar las condiciones laborales, hábitos y estilos de vida relacionadas con la multimorbilidad de adultos mayores con empleos con subsistencia en el centro de Medellín-Colombia, 2016. Material y Métodos: Estudio transversal con fuentes primarias de información a un censo de 686 trabajadores, encuestados previa toma de consentimiento informado, el año 2016. Para este estudio se tomaron 153 trabajadores con ≥ 60 años. Análisis univariado, bivariado y multivariado, para estudiar su multimorbilidad y factores asociados a su labor. Resultados: 77,0% tenía entre 60-69 años; fundamentalmente hombres, 56,0% ganaba <500.000 pesos colombianos. Tenian >20 años en su oficio. El 62,0% presentó multimorbilidad, fundamentalmente por diabetes; hipertensión; obesidad y sintomatología depresiva. Explicaron mayor prevalencia de multimorbilidad (p<0,05) trabajar cerca de aguas residuales (RPA=3,38. IC=1,27;8,96), no tener horario para el consumo de alimentos (RPA=3,01. IC=1,25;7,27) y consumir alimentos en soledad (RPA=3,28. IC=1,31;8,18). Conclusión: Las condiciones que explican multimorbilidad en estos trabajadores, pueden ser revertidas con acciones de promoción de la salud y prevención de la enfermedad, lideradas por el Estado y con su participación activa.

10.

Multimorbilidad en adultos mayores con empleos con subsistencia en las calles y aceras de Medellín, Colombia, 2016
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Garzón Duque, María Osley

; Toro Rivera, José Alejandro

; Rodríguez Ospina, Fabio León

; Cardona Arango, Doris

; Segura Cardona, Ángela María

; Uribe Cárdenas, Paula Andrea

; Martínez Romero, María Camila

Revista de la Asociación Española de Especialistas en Medicina del Trabajo

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2021, Volume 30 N. 4 Pages 475 - 494

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

11.

Microbiological characterization of severe exacerbations in Chronic Obstructive Pulmonary Disease (COPD) in patients admitted to the ICU with or without associated pneumonia: A retrospective cross-sectional study
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Varon, Fabio

; Torres-Caro, Cristina

; Herrera-Diaz, Catalina

; Ali, Abraham

; Hernández-Parra, Angela

; Aguirre-Franco, Carlos

; Uribe-Hernández, Ana María

Infectio

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dec 2019, Volume 23 N. 4 Pages 307 - 312

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Objetivo: Comparar la microbiología de las exacerbaciones graves de EPOC (Enfermedad Pulmonar Obstructiva Crónica) que requieren ingreso a la unidad de cuidados intensivos, con y sin neumonía Métodos: se realizó un estudio transversal retrospectivo que incluyó pacientes con exacerbación grave de EPOC que requieren ingreso a la Unidad de Cuidados Intensivos (UCI). Tomamos muestras microbiológicas y serológicas para estudiar la etiología de la exacerbación y radiografía de tórax para ver si tenía o no una neumonía asociada. Seguimos a los pacientes durante su ingreso en la UCI y evaluamos el resultado de la hospitalización. Resultados: se incluyeron 91 pacientes en el estudio. 53/91 ( 58%) tuvieron confirmación de neumonía. Las bacterias más prevalentes aisladas fueron H. influenzae (25.3%), Moraxella spp (22%), H. parainfluenza (14.3%), Serratia marcescens (13.2%), flora mixta (9.9%) y S. aureus meticilino sensible. (9.9% ). No se pudo demostrar una diferencia estadísticamente significativa entre los dos grupos. Detectamos una resistencia bacteriana del 24,2% en ambos grupos, siendo la más frecuente AMPc (13 casos). Discusión: la neumonía bacteriana en pacientes con EPOC es más alta cuando se compara con pacientes con exacerbación aguda. Aunque no encontramos una diferencia significativa en la microbiología de los grupos con o sin neumonía, existen variables como antecedente de cigarrillo asociadas a tener neumonía. Los pacientes con neumonía así mismo tuvieron mayores índices de severidad.

Abstract Objective: The goal of this study was to compare the microbiology of severe exacerbations of chronic obstructive pulmonary disease (COPD) requiring admission to the intensive care unit (ICU), in patients with pneumonia compared to those that did not have. Methods: We conducted a retrospective cross-sectional study that included patients with severe COPD exacerbation. We took microbiologic and serologic samples to study the etiology of the exacerbation and chest X-ray to see whether or not it had associated pneumonia. Results: Ninety-one patients were included in the study. 53/91 (58%) had pneumonia. The most prevalent bacteria isolated were H. influenzae (25.3%), Moraxella spp (22%), H. parainfluenza (14.3%), Serratia marcescens (13.2%), mixed flora (9.9%) and methicillin-susceptible Staphylococcus aureus (9.9%). A statistically significant difference could not be demonstrated between the two groups. We detected 24.2% of bacterial resistance in both groups, the most frequent being AMPc (13 cases). Discussion: Bacterial pneumonia in COPD patients is higher in comparison with patients with acute exacerbation. Even though we did not find a significant difference in the microbiology of the groups with or without pneumonia, there are variables such as past smoking related to having pneumonia. Patients with pneumonia also had higher severity scores.

https://doi.org/10.22354/in.v23i4.803 733 downloads

12.

Carta al Editor
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Baracaldo A, Rafael Leonardo

; Melo-Uribe, Mario Alexander

; Rodríguez, Laura

; Otero, William

; Grosso, Fabio

Revista colombiana de Gastroenterología

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sep 2018, Volume 33 N. 3 Pages 328 - 331

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

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13.

II Consenso Colombiano para el Manejo de la Osteoporosis Posmenopáusica
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Medina-Orjuela, Adriana

; Rosero-Olarte, Óscar

; Rueda-Plata, Pedro Nel

; Sánchez-Escobar, Fabio

; Chalem-Choueka, Monique

; González-Reyes, Miguel Ángel

; Román-González, Alejandro

; Terront-Lozano, Alexandra

; Páez-Talero, Amanda

; Rueda-Beltz, Camilo

; Builes-Barrera, Carlos Alfonso

; Pérez-Niño, Carlos Augusto

; Fernández-Ávila, Daniel G.

; Vásquez-Awad, David

; González-Devia, Deyanira

; Pinilla-Pabón, Edgar

; Reina-Valdivieso, Eduardo Antonio

; Vásquez-Mejía, Esdras Martín

; Vargas-Grajales, Francisco Iván

; Linares-Restrepo, Francisco

; Altamar-Canales, Geraldine

; Molina-Uribe, Gustavo Adolfo

; Pineda-Acero, Gustavo Adolfo

; Arenas-Quintero, Henry Mauricio

; Vélez-Patino, Jorge Augusto

; Molina-Restrepo, José Fernando

; Jaller-Raad, Juan José

; Londoño-Gutiérrez, Ricardo

Revista Colombiana de Reumatología

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sep 2018, Volume 25 N. 3 Pages 184 - 210

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La Asociación Colombiana de Osteoporosis y Metabolismo Mineral se reunió a principios de 2017 para actualizar el Consenso Colombiano de Osteoporosis, elaborado por primera vez en 2005, un paso que se consideró necesario en vista del subdiagnóstico de esta enfermedad, el impacto esperado del envejecimiento poblacional y los cambios en el tratamiento farmacológico que ha habido desde entonces. Se seleccionó un equipo técnico con especialistas de múltiples áreas y amplia trayectoria, repartidos en 4 grupos de trabajo: definición y epidemiología, diagnóstico, tratamiento farmacológico y medidas no farmacológicas. Luego de una revisión de la literatura científica, en reuniones de trabajo se generaron las definiciones y recomendaciones que se resumen en este documento.

Abstract The Colombian Osteoporosis and Mineral Metabolism Association met in early 2017 to update the Colombian Consensus on Osteoporosis. This was first issued in 2005, and is seen as a necessary step in view of the underdiagnosed status of this disease, and the expected impact of population ageing. A technical team was formed with specialists with long experience across multiple disciplines, who were assigned to four working groups: definitions and epidemiology, diagnosis, pharmacological treatment, and non-pharmacological treatment. After a scientific literature review and a series of meetings, the definitions and recommendations are summarised in this article.

https://doi.org/10.1016/j.rcreu.2018.02.006 11107 downloads

14.

Replacement of animal protein with vegetable protein in the diets of Astyanax altiparanae
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Sussel, Fábio Rosa

; Viegas, Elisabete Maria Macedo

; Evangelista, Mariana Machado

; Gonçalves, Giovani Sampaio

; Salles, Fernando André

; Gonçalves, Ligia Uribe

Acta Scientiarum. Animal Sciences

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dec 2014, Volume 36 N. 4 Pages 343 - 348

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objetivo desse trabalho foi avaliar o efeito da substituição de fontes de proteína animal por fontes proteicas vegetais no desempenho produtivo do Astyanax altiparanae (lambari-do-rabo-amarelo). Cinco dietas experimentais foram formuladas com níveis crescentes de substituição de proteína animal por proteína vegetal. Foi distribuído o total de 9.000 indivíduos (peso médio inicial 1,18 ± 0,12 g, comprimento médio inicial 2,1 ± 0,3 cm) em 20 tanques-rede (1 m³; 450 ind. m-3). Os tanques-rede foram aleatoriamente dispostos em um viveiro (180 m², profundidade: 1,5 m, renovação de água: 10% ao dia). Após 63 dias de cultivo, foi realizada a contagem total dos indivíduos e biometria individual de 20% de cada unidade experimental. Foram avaliados peso e comprimento médios, sobrevivência, conversão alimentar, ganho em biomassa e composição corporal. O delineamento experimental foi inteiramente casualizado, com cinco tratamentos e quatro repetições. A diminuição alcançada no custo de formulação pela inclusão de níveis crescentes de proteína de origem vegetal mais que compensou a ligeira diminuição no ganho em biomassa. Ademais, a inclusão de proteína vegetal resultou em maior deposição lipídica, sugerindo exploração futura de A. altiparanae como alimento funcional.

The aim of this study was to evaluate the effect of replacing animal protein with vegetable protein sources on the productive performance of Astyanax altiparanae (lambari-do-rabo-amarelo). Five experimental diets were formulated with increasing replacement levels of animal protein by vegetable protein. A total of 9000 individuals (initial mean weight 1.18 ± 0.12 g, initial mean length 2.1 ± 0.3 cm) were distributed in 20 net cages (1 m³) with a density of 450 ind. m-3. Cages were randomly placed in a pond (180 m², 1.5 m deep, 10% water renewal per day). After 63 days of cultivation, total count and individual biometrics from 20% of each experimental unit were taken. Mean weight, total length, survival, feed conversion, biomass weight gain and proximate body composition were evaluated. The experimental design was completely randomized with five treatments and four replications. The reduction in the formulation cost achieved by increasing levels of vegetable protein compensated the slight decrease in biomass gain. Besides that, inclusion of vegetable protein resulted in greater fat deposition, suggesting future exploration of A. altiparanae as a functional food.

https://doi.org/10.4025/actascianimsci.v36i4.23836 3414 downloads

15.

Shewhart's control charts and process capability ratio applied to a sewage treatment station
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Orssatto, Fábio

; Vilas Boas, Marcio A.

; Nagamine, Ricardo

; Uribe-Opazo, Miguel A.

Engenharia Agrícola

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aug 2014, Volume 34 N. 4 Pages 770 - 779

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O presente estudo utilizou métodos estatísticos de controle de qualidade para avaliar o desempenho de uma estação de tratamento de esgoto doméstico. A estação de tratamento em questão localiza-se no município de Cascavel, no Estado do Paraná. Os parâmetros avaliados foram: potencial hidrogeniônico, sólidos sedimentáveis, sólidos suspensos totais, demanda química de oxigênio e demanda bioquímica de oxigênio de cinco dias. A análise estatística deu-se através das cartas individuais de Shewhart e índices de capacidade do processo. Conforme as cartas de Shewhart, apenas a variável DBO5,20 apresentou-se sob controle estatístico. Através dos índices de capacidade do processo, observou-se que, com exceção do pH, a estação de tratamento de esgoto doméstico não é capaz de produzir efluente com características que cumpram as especificações ou padrões de lançamentos exigidos pela legislação ambiental.

The current study used statistical methods of quality control to evaluate the performance of a sewage treatment station. The concerned station is located in Cascavel city, Paraná State. The evaluated parameters were hydrogenionic potential, settleable solids, total suspended solids, chemical oxygen demand and biochemical oxygen demand in five days. Statistical analysis was performed through Shewhart control charts and process capability ratio. According to Shewhart charts, only the BOD(5.20) variable was under statistical control. Through capability ratios, we observed that except for pH the sewage treatment station is not capable to produce effluents under characteristics that fulfill specifications or standard launching required by environmental legislation.

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