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“Star of Bethlehem sign” in the analysis of the evolution of brain lesions during and after treatment for neuroparacoccidioidomycosis
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Santana, Larissa M.

; Peçanha, Paulo Mendes

; Falqueto, Aloísio

; Kruschewsky, Wdson L. M.

; Grão-Velloso, Tânia Regina

; Gonçalves, Sarah Santos

; Rosa-Júnior, Marcos

Radiologia Brasileira

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2023, Volume 56 N. 4 Pages 195 - 201

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective: To describe the clinical and radiological evolution of lesions during and after treatment in patients diagnosed with neuroparacoccidioidomycosis (NPCM). Materials and Methods: This was a retrospective study of the medical records, computed tomography scans, and magnetic resonance imaging (MRI) scans of patients with NPCM treated between September 2013 and January 2022. Results: Of 36 cases of NPCM, eight were included in the study. One patient presented only with pachymeningeal and skull involvement, and seven presented with pseudotumors in the brain. Collectively, the eight patients presented with 52 lesions, of which 46 (88.5%) were supratentorial. There were 32 lesions with a diameter ≤ 1.2 cm, of which 27 (84.4%) disappeared during the treatment. In three cases, there were lesions > 1.2 cm that showed a characteristic pattern of evolution on MRI: an eccentric gadolinium contrast-enhanced nodule, with a subsequent decreased in the size and degree of contrast enhancement of the lesions. Conclusion: In NPCM, supratentorial lesions seem to predominate. Lesions ≤ 1.2 cm tend to disappear completely during treatment. Lesions > 1.2 cm tend to present with a similar pattern, designated the “Star of Bethlehem sign”, throughout treatment.

Resumo Objetivo: Descrever a evolução clínica e radiológica das lesões durante e após o tratamento de pacientes diagnosticados com neuroparacoccidioidomicose (NPCM). Materiais e Métodos: Revisamos os prontuários médicos, estudos de tomografia computadorizada e ressonância magnética (RM) de pacientes com NPCM de nossa instituição, no período de setembro de 2013 a janeiro de 2022. Resultados: Dos 36 casos de NPCM, oito foram incluídos no presente estudo. Um caso apresentava apenas envolvimento paquimeníngeo e ósseo craniano e sete casos apresentavam lesões encefálicas pseudotumorais, totalizando 52 lesões, sendo 46 (88,5%) supratentoriais. Dentre 32 lesões com diâmetro ≤ 1,2 cm, 27 (84,4%) apresentaram resolução completa durante o tratamento. Três casos apresentaram padrão semelhante de evolução da lesão na RM em lesões > 1,2 cm, caracterizado pelo aparecimento de nódulo excêntrico com impregnação pelo gadolínio, seguido de redução das dimensões e do realce nodular pelo contraste nos estudos subsequentes. Conclusão: A NPCM apresenta-se predominantemente com lesões supratentoriais. Lesões ≤ 1,2 cm tendem a desaparecer completamente durante o tratamento. Lesões > 1,2 cm tendem a apresentar um padrão de imagem de RM característico ao longo do tratamento, descrito como o “sinal da Estrela de Belém”.

https://doi.org/10.1590/0100-3984.2023.0030

Classificação dos tumores hematopoéticos e linfoides de acordo com a OMS: padronização da nomenclatura em língua portuguesa, 4ª edição
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Zerbini, Maria Cláudia Nogueira

; Soares, Fernando Augusto

; Morais, José Carlos

; Vassallo, José

; Velloso, Elvira Deolinda Rodrigues Pereira

; Chaufaille, Maria de Lourdes L. F

; Chiattone, Carlos Sergio

; Aldred, Vera Lucia

; Siqueira, Sheila Aparecida Coelho

; Alves, Antonio Correia

; Castelli, Jussara Bianchi

; Oliveira, Claudia Regina Gomes Mendes Cardim de

; Menezes, Yara de

; Paes, Roberto Pinto

Jornal Brasileiro de Patologia e Medicina Laboratorial

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dec 2011, Volume 47 N. 6 Pages 643 - 648

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: A classificação da Organização Mundial da Saúde (OMS) para os tumores do tecido hematopoético e linfoide (4ª edição, 2008) representa uma revisão atualização da 3ª edição publicada em 2001. A tradução da nomenclatura utilizada para identificar as entidades descritas deve ser clara, precisa e uniforme no sentido de reproduzir de forma correta as diversas entidades clinicopatológicas para clínicos, patologistas e pesquisadores envolvidos na área da onco-hematopatologia. OBJETIVO: Os autores apresentam uma proposta de atualização e padronização terminológica em língua portuguesa, com base na OMS/2008

INTRODUCTION: The World Health Organization (WHO) classification of hematopoietic and lymphoid tissue (4th edition, 2008) tumors constitutes an updated review of the 3rd edition published in 2001. The translation of the nomenclature used to describe the entities should be clear, precise and uniform so that clinicians, pathologists and researchers involved in the onco-hematopathological area may identify them accurately. OBJECTIVE: With this purpose, the authors present an updated proposal and a terminological standardization in Portuguese based on WHO/2008

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Classificação da Organização Mundial da Saúde para os tumores dos tecidos hematopoético e linfoide, 4ª edição, 2008: principais modificações introduzidas em relação à 3ª edição, 2001
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Zerbini, Maria Claudia Nogueira

; Soares, Fernando Augusto

; Velloso, Elvira Deolinda Rodrigues Pereira

; Chaufaille, Maria de Lourdes L. F

; Paes, Roberto Pinto

Revista da Associação Médica Brasileira

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feb 2011, Volume 57 N. 1 Pages 6 - 73

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A Classificação da Organização Mundial da Saúde (OMS) para os tumores do tecido hematopoético e linfoide (4ª edição, 2008)¹ representa uma atualização da 3ª edição, 2001². Apresentamos a seguir um resumo dessas alterações nos grupos das doenças mieloproliferativas, mileodisplásicas, leucemias mieloides agudas, neoplasias de células precursoras B e T, e neoplasias de células B, T e NK maduras. O entendimento das alterações genético-moleculares e os resultados alcançados com propostas terapêuticas inovadoras nesses grupos de doenças demandam constante reavaliação de sua classificação, justificando as alterações importantes aqui discutidas1,3-5.

The World Health Organization (WHO) Classification of tumors of hematopoietic and lymphoid tissues (4th edition, 2008)¹ presents an updated version of the 3rd edition published in 2001². A summary of these changes relates to the groups of chronic myeloproliferative disorders, myelodisplasia, acute myeloid leukemias, neoplasms of precursor B and T cells and neoplasms derived of mature B, T and NK cells. A better understanding of molecular genetic changes and results achieved with innovative therapeutic approaches in these groups of diseases requires constant reassessment of the classifications, supporting the major changes discussed here, including interesting comments from literature1, 3-5.

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Ventilatory and muscular assessment in healthy subjects during an activity of daily living with unsupported arm elevation
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Panka, Giselle F. L.

; Oliveira, Marina M.

; França, Danielle C.

; Parreira, Verônica F.

; Britto, Raquel R.

; Velloso, Marcelo

Brazilian Journal of Physical Therapy

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aug 2010, Volume 14 N. 4 Pages 337 - 344

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: Pacientes com doença pulmonar obstrutiva crônica (DPOC) relatam dispneia quando realizam atividades da vida diária (AVD) com membros superiores (MMSS) elevados. Estudar as alterações do padrão respiratório e a atividade eletromiográfica dos músculos acessórios da respiração desses pacientes nas AVD pode contribuir para esclarecer os determinantes de dispneia. Entretanto, não se encontrou, na literatura, um padrão de normalidade, fazendo-se necessário estudar, primeiramente, o comportamento dessas variáveis em saudáveis. OBJETIVOS: Verificar, em indivíduos saudáveis, a existência de mudanças no padrão respiratório e na ativação do músculo esternocleidomastoideo (ECM) durante a realização de uma AVD com os MMSS elevados e sem apoio. MÉTODOS: Treze voluntários masculinos, com média de idade 60,57 (6,42) anos, com valores espirométricos normais para idade e sexo foram avaliados com eletromiografia (EMG) de superfície e pletismografia respiratória por indutância (PRI), coletadas durante o repouso e na atividade de pentear cabelos com MMSS elevados sem apoio. A distribuição dos dados foi analisada pelo teste Shapiro-Wilk. Para a comparação entre as fases avaliadas, utilizou-se ANOVA e, quando a diferença foi considerada significativa (p<0,05), aplicou-se o teste de Tuckey. RESULTADOS: A PRI, durante a AVD, mostrou aumentos significativos do volume corrente, do volume minuto, da frequência respiratória e do fluxo inspiratório médio. Observou-se assincronia toracoabdominal tanto em porcentagem de assincronia na inspiração e na expiração quanto na análise do Ângulo de Fase (p<0,05). A EMG mostrou aumento no recrutamento do ECM (p<0,05). CONCLUSÕES: Indivíduos saudáveis apresentam maior ativação do músculo ECM e modificam o padrão respiratório durante AVD com MMSS elevados sem apoio, gerando assincronia toracoabdominal.

INTRODUCTION: Patients with chronic obstructive pulmonary disease (COPD) report dyspnea when performing activities of daily living (ADLs) with elevated upper limbs. To elucidate the determinants of dyspnea, it is important to study the changes in the respiratory pattern of these patients and the electromyographic activity of their accessory muscles of respiration during ADLs. In the literature, there are no reports of a normative parameter, therefore it is necessary to study how these variables behave in healthy subjects. OBJECTIVES: To verify, in healthy subjects, the existence of changes in the respiratory pattern and activation of the sternocleidomastoid (SCM) muscle during an ADL with unsupported arm elevation. METHODS: Thirteen male subjects, 60.57 (±6.42) years old, with normal spirometry values for age and sex, were evaluated using surface electromyography (EMG) and respiratory inductive plethysmography (RIP) collected at rest and during the activity of combing their hair with elevated and unsupported upper limbs. The data distribution was assessed using Shapiro-Wilk's test. ANOVA was used to compare the phases, and when the difference was significant (p<0.05), Tukey's test was applied. RESULTS: The RIP during the ADL showed a significant increase in tidal volume, minute ventilation, respiratory frequency and mean inspiratory flow. Thoracoabdominal asynchrony was identified in percentage of asynchrony in inspiration, expiration, and Phase Angle (p<0.05). The EMG showed an increase in SMC muscle recruitment (p<0.05). CONCLUSIONS: Healthy subjects increased their SCM muscle activation and changed their breathing pattern when performing the ADL with unsupported arm elevation, resulting in thoracoabdominal asynchrony.

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Inflammatory response in a rat model of gastroschisis is associated with an increase of NF-kappaB
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Sbragia, L.

; Schmidt, A.F.

; Moraes, S.

; Bittencourt, D.G.

; Gonçalves, F.L.L.

; Pereira, L.A.V.D.

; Velloso, L.A.

Brazilian Journal of Medical and Biological Research

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feb 2010, Volume 43 N. 2 Pages 160 - 165

Abstract: En | Text: En | PDF: En

Babies with gastroschisis have high morbidity, which is associated with inflammatory bowel injury caused by exposure to amniotic fluid. The objective of this study was to identify components of the inflammatory response in the intestine and liver in an experimental model of gastroschisis in rats. The model was surgically created at 18.5 days of gestation. The fetuses were exposed through a hysterotomy and an incision at the right of the umbilicus was made, exposing the fetal bowel. Then, the fetus was placed back into the uterus until term. The bowel in this model had macro- and microscopic characteristics similar to those observed in gastroschisis. The study was conducted on three groups of 20 fetuses each: gastroschisis, control, and sham fetuses. Fetal body, intestine and liver weights and intestine length were measured. IL-1β, IL-6, IL-10, TNF-α, IFN-γ and NF-kappaB levels were assessed by ELISA. Data were analyzed statistically by ANOVA followed by the Tukey post-test. Gastroschisis fetuses had a decreased intestine length (means ± SD, 125 ± 25 vs 216 ± 13.9; P < 0.005) and increased intestine weight (0.29 ± 0.05 vs 0.24 ± 0.04; P < 0.005). Intestine length correlated with liver weight only in gastroschisis fetuses (Pearson’s correlation coefficient, r = 0.518, P = 0.019). There were no significant differences in the concentrations of IL-1β, TNF-α or IFN-γ in the intestine, whereas the concentration of NF-kappaB was increased in both the intestine and liver of fetuses with gastroschisis. These results show that the inflammatory response in the liver and intestine of the rat model of gastroschisis is accompanied by an increase in the amount of NF-kappaB in the intestine and liver.

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O uso da associação azitromicina e N-metil glucamina no tratamento da leishmaniose cutânea causada por Leishmania (Leishmania) amazonensis em camundongos C57BL6
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Sampaio, Raimunda Nonata Ribeiro

; Lucas, Íris Campos

; Costa Filho, Arnoldo Velloso da

Anais Brasileiros de Dermatologia

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apr 2009, Volume 84 N. 2 Pages 125 - 128

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

FUNDAMENTOS: O tratamento de primeira escolha da leishmaniose tegumentar americana é a N-metil-glucamina que tem alta toxicidade, exige administração parenteral e nem sempre cura. A azitromicina mostrou ação in vitro e resultado contraditório na doença humana. OBJETIVO: Verificar se a associação N-metil-glucamina+azitromicina é mais eficaz do que N-metil-glucamina no tratamento da leishmaniose experimental. MÉTODOS: 25 camundongos inoculados com a cepa C57BL/6 de L. (L.) amazonensis foram divididos em dois grupos. Um foi tratado com 400mgSbV/kg/dia de N-metil-glucamina associado a 200mg/kg/dia de azitromicina durante 20 dias, e o outro com N-metil-glucamina, na mesma dose, durante o mesmo tempo. Foi feita avaliação clínica e parasitológica com análise estatística. RESULTADO: Na avaliação clínica, pesquisa de amastigotas e das culturas, não houve diferença estatística. Verificou-se, entretanto, diferença significante no resultado das culturas realizadas através de diluição limitante, que desfavoreceu a associação NMG+ azitromicina. CONCLUSÃO: A associação N-metil-glucamina e azitromicina não demonstrou mais eficácia do que o N-metil-glucamina em uso isolado.

BACKGROUND: The first choice treatment for cutaneous Leishmaniasis is N-methyl glucamine: it has high toxicity, requires parenteral administration and cure is not always reached. Azythromycin showed in vitro action and controversial results in humans with the disease. OBJECTIVE: To verify if the association of N-methyl-glucamine - azythromycin is more effective than N-methyl-glucamine alone for the treatment of experimental Leishmaniasis. METHODS: Twenty-five C57BL/6 mice were inoculated with L. (L.) amazonensis strain and divided into two groups. One group was treated with 400mgSbV/kg/day of N-methyl glucamine and 200mg/kg/day of azythromycin for 20 days and the other group received the same dose of N-methyl glucamine alone during the same period of time. Clinical and parasitological evaluations were submitted to statistical analyses. RESULTS: There was no statistical difference in clinical analysis, in amastigotes investigation and in cultures. There were significant differences in cultures using limiting dilution, which showed lower efficacy of the association N-methyl glucamine -azythromycin. CONCLUSION: N-methyl glucamine-azythromycin association was not more effective than N-methyl glucamine alone.

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Bipedal locomotion in Tropidurus torquatus (Wied, 1820) and Liolaemus lutzae Mertens, 1938
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Rocha-Barbosa, O.

; Loguercio, MFC.

; Velloso, ALR.

; Bonates, ACC.

Brazilian Journal of Biology

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aug 2008, Volume 68 N. 3 Pages 649 - 655

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O bipedalismo apareceu em inúmeras ocasiões em famílias de lagartos filogeneticamente diversas. Neste trabalho, descrevemos, pela primeira vez, locomoção bipedal em lagartos sul-americanos, o lagarto de hábito terrestre Liolaemus lutzae e o generalista Tropidurus torquatus. Os lagartos foram filmados correndo em uma pista de corrida e as seqüências foram analisadas quadro a quadro. A postura corporal, como um todo, divergiu bastante durante a locomoção bipedal das duas espécies, mesmo quando não houve diferença significativa em relação ao desempenho locomotor. O comportamento locomotor de L. lutzae é, em geral, similar ao observado em outros lagartos especialistas em solos arenosos. Certas particularidades são comuns, como a postura digitígrada no momento de apoio e durante a fase de apoio; ângulos do corpo e postura da cauda. Em contraste, T. torquatus exibiu altos ângulos corporais e arrastava sua cauda, numa postura comparada à dos lagartos basiliscos. Este tipo de postura corporal pode estar relacionado com certas características e obstáculos de um microhabitat como ao redor de rios e riachos (basiliscos) e uma vegetação de arbustos compacta (T. torquatus).

Bipedalism has evolved on numerous occasions in phylogenetically diverse lizard families. In this paper we describe, for the first time, bipedal locomotion on South American lizards, the sand-dweller Liolaemus lutzae and the generalist Tropidurus torquatus. The lizards were videotaped running on a racetrack and the sequences were analyzed frame by frame. The body posture, as a whole, diverged a lot during bipedal locomotion between the two species, even though there was no difference regarding their sprint performance. The locomotor behavior of L. lutzae is, in general, more similar to the one observed on other sand-dweller lizards. Certain particularities are common, such as the digitigrade posture at footfall and throughout stance, trunk angles; and tail posture. In contrast, T. torquatus exhibited high trunk angles and dragged its tail, in a posture compared to basilisks. This body posture could be related to certain characteristics and obstacles of a microhabitat such as the one around lakes and streams (basilisks) and the one with compact shrubby vegetation (T. torquatus).

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Structure of claws and toes of two tropidurid lizard species of Restinga from Southeastern Brazil: adaptations to the vertical use of the habitat
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Carvalho Ribas, Sueli

; Velloso, Ana Lucia Rosario

; Teixeira-Filho, Pedro

; Rocha-Barbosa, Oscar

; Evangelista, Heitor

; Alves dos Santos, Elaine

Revista chilena de historia natural

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dec 2004, Volume 77 N. 4 Pages 599 - 606

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Tropidurus torquatus and Liolaemus lutzae, found in a restinga habitat, show some morphological differences associated with differential microhabitats use. There were made measurements of the snout-vent length, length and width of the largest toe of hand and foot, and length, width, height and curvature of the claws. We counted the number of adhesive lamellae of the largest toe of each member. T. torquatus has larger toes, greater number of adhesive lamellae and higher and more curve claws than L. lutzae. No significant differences in toe and claw widths were found. These results suggest that the differences found in the morphology of toes and claws of these two species would be associated with the differential microhabitat use. T. torquatus has morphological adaptations that allow it to use the microhabitat both vertically or horizontally, while L. lutzae use it only horizontally

Tropidurus torquatus y Liolaemus lutzae hallados en un hábitat de restinga, muestran algunas diferencias morfológicas asociadas a el uso diferencial de microhábitats. Se realizaron mediciones de la longitud "snout-vent", longitud y ancho del dedo mayor de la mano y el pie y, longitud, ancho, altura y curvatura de las garras. Se contó el número de lamelas adhesivas del dedo mayor de cada miembro. T. torquatus posee dedos más grandes, mayor número de lamelas adhesivas y garras más altas y curvadas que L. lutzae. No se hallaron diferencias significativas en los anchos de dedos y garras. Estos resultados sugieren que las diferencias encontradas en la morfología de dedos y garras de estas dos especies estarían asociadas con el uso diferencial del microhábitat. T. torquatus posee adaptaciones que le permiten utilizar el microhábitat tanto vertical como horizontalmente, mientras que L. lutzae solamente lo utiliza en forma horizontal

3876 downloads Cited 3 times in SciELO

Non-obese adult onset diabetes with oral hypoglycemic agent failure: islet cell autoantibodies or reversible beta cell refractoriness?
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Sá, J.R.

; Silva, R.C.

; Nasri, F.

; Aguade, L.C.M.

; Velloso, L.

; Chacra, A.R.

; Dib, S.A.

Brazilian Journal of Medical and Biological Research

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oct 2003, Volume 36 N. 10 Pages 1301 - 1309

Abstract: En | Text: En | PDF: En

Pancreatic ß cell function and insulin sensitivity, analyzed by the homeostasis model assessment, before and after 24 weeks of insulin therapy were studied and correlated with the presence of autoantibodies against ß cells (islet cell and anti-glutamic acid decarboxylase antibodies), in a group of 18 Brazilian lean adult non-insulin-dependent diabetes mellitus (NIDDM) patients with oral hypoglycemic agent failure (OHAF). Median fasting plasma glucose before and after insulin treatment was 19.1 and 8.5 mmol/l, respectively (P < 0.001); median HbA1c was 11.7% before vs 7.2% after insulin treatment (P < 0.001). Forty-four percent of the patients were positive (Ab+) to at least one autoantibody. Fasting C-peptide levels were lower in Ab+ than Ab- patients, both before (Ab+: 0.16 ± 0.09 vs Ab-: 0.41 ± 0.35 nmol/l, P < 0.003) and after insulin treatment (Ab+: 0.22 ± 0.13 vs Ab-: 0.44 ± 0.24 nmol/l, P < 0.03). Improvement of Hß was seen in Ab- (median before: 7.3 vs after insulin therapy: 33.4%, P = 0.003) but not in Ab+ patients (median before: 6.6 vs after insulin therapy: 20.9%). These results show that the OHAF observed in the 18 NIDDM patients studied was due mainly to two major causes: autoantibodies and ß cell desensitization. Autoantibodies against ß cells could account for 44% of OHAF, but Ab- patients may still present ß cell function recovery, mainly after a period of ß cell rest with insulin therapy. However, the effects of ß cell function recovery on the restoration of the response to oral hypoglycemic agents need to be determined.

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Propriedades químicas de um Cambissolo cultivado com cana-de-açúcar, com preservação do palhiço e adição de vinhaça por longo tempo
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Canellas, L. P.

; Velloso, A. C. X.

; Marciano, C. R.

; Ramalho, J. F. G. P.

; Rumjanek, V. M.

; Rezende, C. E.

; Santos, G. A.

Revista Brasileira de Ciência do Solo

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oct 2003, Volume 27 N. 5 Pages 935 - 944

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O presente estudo foi realizado a partir de amostras de um Cambissolo Háplico Ta Eutrófico vértico, localizado em Campos dos Goytacazes, norte do estado do Rio de Janeiro, e submetido ao cultivo por longo tempo com cana-de-açúcar. Em uma das áreas de coleta, a cana foi cultivada, por 55 anos, sem a queima por ocasião da colheita. Na outra, por 35 anos, houve a adição anual de cerca de 120 m³ ha-1 de vinhaça, por meio de irrigação por aspersão e colheita com a cana queimada. Outras duas áreas, respectivamente adjacentes a essas, onde se realizou a queima por ocasião da colheita durante 55 anos e não se procedeu à adição de vinhaça por 35 anos e colhida com queima do canavial, foram utilizadas para coleta de solo. As amostras foram obtidas nas profundidades de 0-0,20 m e 0,20-0,40 m e tiveram determinados o pH em água, o fósforo disponível, as bases trocáveis, a capacidade de troca catiônica, a saturação por bases, os teores de micronutrientes, de carbono e de nitrogênio. Realizou-se, ainda, o fracionamento da matéria orgânica humificada. O manejo com cana crua e o com adição de vinhaça aumentaram os teores de macro e micronutrientes, em comparação com o manejo cana queimada e sem adição de vinhaça, respectivamente. Na camada superficial do solo (0-0,20 m), o teor de carbono variou de 13,13 g kg-1, na cana queimada, a 22,34 g kg-1, na cana crua, e de 15,71 g kg-1, na cana sem adição de vinhaça, a 18,33 g kg-1, na cana que anualmente recebeu vinhaça. A melhora nos atributos químicos do solo favoreceu a formação de substâncias húmicas alcalino-solúveis mais polimerizadas.

This study was undertaken in Campos dos Goytacazes, northern State of Rio de Janeiro, based on soil samples of a vertic Fluventic Eutrochrepts, which had been cultivated with sugarcane for several decades. In one situation, the crop had been cultivated for 55 years without burning the residues at harvesting. On another sugarcane plantation, harvest residues had been burned, and vinasse inputs applied by sprinkle irrigation at a rate of 120 m³ ha-1 yr-1 during 35 years. Soil samples were collected from the soil layers 0-0,20 m and 0,20-0,40 m to evaluate and determinate the pH, available P, exchangeable bases, cation exchange capacity, double acid extractable micronutrients, total N, and oxidizable carbon, as well as the fractionation of the humified organic matter. Results indicate that the preservation of crop residue on the soil surface and, to a lesser extent, the addition of vinasse, increase the macro and micronutrients contents. Carbon contents in the superficial layer (0-0,20 m) ranged from 13.13 g kg-1 in the burned cane to 22.34 g kg-1 in the unburned cane, and from 15.71 g kg-1 in the cane without vinasse to 18.33 g kg-1 in the cane under vinasse application. The improvement of the chemical soil attributes favored the formation of more polymerized alkaline-soluble humic substances.

9366 downloads Cited 45 times in SciELO

11.

The growing competition in Brazilian science: rites of passage, stress and burnout
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de Meis, L.

; Velloso, A.

; Lannes, D.

; Carmo, M.S.

; de Meis, C.

Brazilian Journal of Medical and Biological Research

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sep 2003, Volume 36 N. 9 Pages 1135 - 1141

Abstract: En | Text: En | PDF: En

Brazil's scientific community is under pressure. Each year there is an increase in its contribution to international science and in the number of students who are trained to do research and teach at an advanced level. Most of these activities are carried out in state and federal universities, but with government funding that has decreased by more than 70% since 1996. Interviews with graduate students, post-doctoral fellows and professors in one university department with a strong research tradition illustrate the level of stress engendered by the conflict between increasing competition and diminishing resources, and serve to underscore the negative effects on creativity and on the tendency to choose science as a career.

8533 downloads Cited 21 times in SciELO

12.

The gravitational wave detector "Mario Schenberg": status of the project
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Aguiar, O.D.

; Andrade, L.A.

; Camargo Filho, L.

; Costa, C.A.

; Araujo, J.C.N. de

; Rey Neto, E.C. del

; Souza, S.T. de

; Fauth, A.C.

; Frajuca, C.

; Frossati, G.

; Furtado, S.R.

; Furtado, V.G.S.

; Magalhães, N.S.

; Marinho Jr., R.M.

; Matos, E.S.

; Meliani, M.T.

; Melo, J.L.

; Miranda, O.D.

; Oliveira Jr., N.F.

; Ribeiro, K.L.

; Salles, K.B.M.

; Stellati, C.

; Velloso Jr., W.F.

Brazilian Journal of Physics

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dec 2002, Volume 32 N. 4 Pages 866 - 868

Abstract: En | Text: En | PDF: En

The first phase of the Brazilian Graviton Project is the construction and operation of the gravitational wave detector Mario Schenberg at the Physics Institute of the University of São Paulo. This gravitational wave spherical antenna is planned to feature a sensitivity better than h = 10-21 Hz-1/2 at the 3.0-3.4 kHz bandwidth, and to work not only as a detector, but also as a testbed for the development of new technologies. Here we present the status of this detector.

2078 downloads Cited 1 time in SciELO

13.

Características estruturais de ácidos húmicos isolados de solos com adição de resíduos orgânicos de origem urbana: composição elementar, análise de RMN 13C e Pi-CG/EM
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Canellas, L. P.

; Moraes, A. A.

; Rumjanek, V. M.

; Garcia, M. R.

; Guridi, F.

; Santos, G. A.

; Velloso, A. C. X.

; Braz-Filho, R.

Revista Brasileira de Ciência do Solo

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jun 2002, Volume 26 N. 2 Pages 333 - 341

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Foram avaliadas as alterações nas características estruturais de ácidos húmicos (AH) decorrentes da adição de matéria orgânica de resíduos urbanos. Os AH foram extraídos da camada superficial (0-20 cm) de um Argissolo Vermelho-Amarelo (Seropédica, RJ) e de um Latossolo Vermelho Amarelo (Piraí, RJ), ambos tratados com o equivalente a 80 t ha-1 (em base seca) de composto de lixo urbano e lodo de estação de tratamento de esgotos. O tempo de incubação em laboratório foi de 24 semanas à temperatura ambiente e umidade mantida na capacidade de campo. Para caracterizar os AH, foram utilizadas a análise elementar, a ressonância magnética nuclear (RMN) de 13C e Pirólise acoplada à cromatografia gasosa e a espectrometria de massas (Pi-CG/EM). A análise de RMN 13C permitiu observar alterações na composição molecular dos AH de forma clara, principalmente, pelo aumento do teor de C mono e di oxigenados (δC 50-110) e pela diminuição dos teores de grupos CH2 e CH3 (δC 50-110). O aumento no teor de carboidratos evidencia a presença de estruturas mais lábeis nos AH com adição dos resíduos. Em adição, a técnica de Pi-CG/EM permitiu verificar diferenças qualitativas significativas nos compostos orgânicos, provenientes da fragmentação térmica dos AH com incorporação de novas estruturas, sobretudo da fração lipídica e de derivados de carboidratos (furanos), nas amostras de solos tratados com ambos os resíduos orgânicos. O uso em conjunto das técnicas analíticas de RMN 13C e de Pi-CG/EM foi eficiente para avaliar as mudanças na composição molecular de ácidos húmicos decorrentes da adição de resíduos orgânicos de origem urbana.

The structural features of humic acids (HA) after addition of organic matter from urban residues were evaluated. The HAs were extracted from the surface (0-20 cm) of an ultisol (Seropédica, RJ) and oxisol (Piraí, RJ) which had been treated with the equivalent of 80 t ha-1 (dry material) of compost from urban waste and also sewage sludge. The incubation time in the laboratory was 24 weeks under room temperature and humidity at field capacity. Tha HAs were characterized by elemental analysis, 13C NMR spectroscopy and pyrolysis coupled to gas chromatography/mass spectrometry (Py-GC/MS). NMR spectroscopy allowed the clear observation of alterations in the molecular composition of the HAs, mainly through the increase in the content of mono and dioxygenated carbon atoms (δ 50-100) and decrease in the content of CH2 and CH3 groups (δ 0-40). The increase in the amount of carbohydrates suggests the presence of more labile structures in the HAs with organic residues amendment. In addition, Py-GC/MS led to the observation of significant qualitative differences between the compounds which arose from the thermal fragmentation of HAs, mainly lipids and carbohydrate derivatives (such as furan), for soil samples treated with either organic residues. The coupling of 13C NMR spectroscopy and Py-GC/MS has proven useful in evaluating physical changes in HAs isolated from soils treated with urban organic residues.

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14.

Mobilidade de metais pesados em solo tratado com resíduo siderúrgico ácido
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Amaral Sobrinho, N. M. B.

; Velloso, A. C. X.

; Costa, L. M.

; Oliveira, C.

Revista Brasileira de Ciência do Solo

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jun 1998, Volume 22 N. 2 Pages 345 - 353

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Amostras do horizonte Bt de um Podzólico Vermelho-Amarelo (PV), predominante no aterro-piloto de resíduos industriais (ARSI) da Companhia Siderúrgica Nacional (CSN), foram acondicionadas, em 1992, em colunas de vidro com 5,4 cm de diâmetro e 37 cm de altura. Sobre essas amostras de solo foram colocadas amostras de um resíduo ácido da CSN na proporção solo-resíduo de 4:1 (conforme a concepção básica do projeto do ARSI). Tal sistema resíduo-solo foi lixiviado com 50 volumes-poro de água deionizada, com pH 4,5, com o objetivo de avaliar a movimentação de Cr, Mn, Ni, Cu, Zn, Cd e Pb nas colunas. Depois da lixiviação, removeu-se o resíduo do topo das colunas, e seccionaram-se as amostras de solo em 4 partes iguais. Os metais pesados das amostras do resíduo e do solo foram extraídos seqüencialmente. 0 Pb, Cu e Cr mobilizados do resíduo ficaram retidos nos primeiros 5 cm da coluna de solo. 0 Zn, Mn, Ni e Cd tiveram aumento da concentração em profundidade. Nos efluentes das colunas com o resíduo, foram observadas concentrações de Mn e Ni bem superiores aos padrões permitidos pela Fundação Estadual de Engenharia do Meio Ambiente (FEEMA, 1985).

Air dried subsurface samples of a heavy textured Red-Yellow Podzolic soil, representative of the industrial solid residue pilot landfill (ISRL) of the National Steel Works (Companhia Siderúrgica Nacional-CSN), were packed in 5.4 cm width and 37 cm high glass columns. An acid iron smelter residue was placed on the top of the soil columns to make a 4:1 soil-residue ratio, in consonance with the basic CSN project. To evaluate Cr, Mn, Ni, Cu, Zn, Cd and Pb mobilities, the system soil-residue was leached with 50 pore volumes of deionized water at pH 4.5. After leaching, the residue was removed from the tops and the soil columns were sectioned into 4 equal parts. The heavy metals in the residue and in the soil samples were sequentially extracted. Pb, Cr and Cu dissolved from the residues were retained in the upper 0-5 cm soil columns. Zn, Mn, Ni and Cd showed the same distribution pattern, i.e, increased concentration with depth. In the effluents leaching out the columns (with the residue on the top) the levels of Mn and Ni were higher than the standard limits allowed by FEEMA (1985).

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15.

Schistosomiasis mansoni in the region of the Triângulo Mineiro, State of Minas Gerais, Brazil
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Carvalho, Omar dos Santos

; Massara, Cristiano Lara

; Silveira Neto, Horacio Velloso

; Alvarenga, Andréa Gersen

; Vidigal, Teofânia H. D. Amorim

; Guerra, Henrique L.

; Santos, Maria Angela A.

; Chaves, Adelú

; Katz, Naftale

Memórias do Instituto Oswaldo Cruz

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dec 1994, Volume 89 N. 4 Pages 509 - 512

Abstract: En | Text: En | PDF: En

In order to reevaluate the possible presence of schistosomiasis mansoni in the Triângulo Mineiro, one of the areas of the State of Minas Gerais where this parasite is not commonly found, malacological survey and fecal examinations were undertaken in the region between October 1990 and June 1992. A sample of 7,032 1st grade school children from 29 counties had their feces examined using the Kato-Katz method. Amongst the children examined, two from Planura and one from each countie of Capinópolis, Conceição das Alagoas, Uberaba, Uberlândia, Prata and Gurinhatã were positive for Schistosoma mansoni. None of the children were identified as being autoctonous cases. In the malacological survey, 5,406 planorbid snails were examined. The specimens were identified morphologically and examined for S. mansoni by squashing between glass plates. The species were identified as Biomphalaria tenagophila in three counties, as B. straminea in ten and B. intermedia in 16. No snails were found in eight other counties studies. The snails were found to be negative for S. mansoni. The presence of intermediate hosts for S. mansoni, associated with parasitized individuals emphasizes the necessity of epidemiological surveillance for schistosomiasis in the region of Triângulo in the State of Minas Gerais.

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