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Abstract Background Cardiotoxicity is the main complication related to cancer therapy. Studies indicate that global longitudinal strain is an early detector of subclinical dysfunction of the left ventricle, preceding the decline in ejection fraction (EF). However, the reproducibility of such methodology has not been tested outside specialized centers. Objectives To assess the frequency of subclinical cardiotoxicity and to compare global longitudinal strain and EF measurements during the clinical course of patients undergoing chemotherapy for breast cancer. Methods This was an observational prospective study of 78 adult women who underwent serial echocardiograms (baseline and 1, 3, and 6 months after the beginning of chemotherapy), to evaluate biplane and 3D EF and global longitudinal strain. Cardiotoxicity and subclinical dysfunction were defined according to American Society of Echocardiography/European Association of Cardiovascular Imaging criteria. Statistical significance was set at p < 0.05. Results The mean age of the patients was 50.1 ± 11.48 years. The frequency of subclinical cardiotoxicity (defined by global longitudinal strain) was 14.9% after 30 days of chemotherapy, 16.7% after 3 months, and 19.7% after 6 months, compared to 4.5%, 3%, and 6.6%, respectively, when clinical cardiotoxicity was determined according to EF. The group that developed subclinical cardiotoxicity by 30 days (group A) had a higher frequency of clinical cardiotoxicity at 3 months (p=0.028) and a lower mean biplane EF after 30 days (p= 0.036) than the group that showed no evidence of subclinical cardiotoxicity (group B). Conclusion Subclinical cardiotoxicity was frequent and began early, being associated with a drop in EF during the clinical course.

https://doi.org/10.36660/ijcs.20210089

Nursing assistance in patient care with external ventricular drain: a scoping review
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Sakamoto, Victoria Tiyoko Moraes

; Vieira, Tainara Wink

; Viegas, Karin

; Blatt, Carine Raquel

; Caregnato, Rita Catalina Aquino

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 2 elocation e20190796

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: mapear as evidências disponíveis acerca dos cuidados de enfermagem direcionados ao paciente adulto em uso de derivação ventricular externa. Métodos: trata-se de uma revisão utilizando o método scoping review. Resultados: inicialmente, identificaram-se 965 estudos e, após os critérios de elegibilidade, obteve-se amostra de 54 publicações. Cada um deles foi avaliado de acordo com o GRADE, resultando em três estudos com qualidade alta; 14 com qualidade moderada; 32 com qualidade baixa; e cinco com qualidade muito baixa. Destacaram-se 20 cuidados de enfermagem, subdivididos em nove categorias como: sistema de drenagem; posicionamento e mobilização no leito; cuidados com o cateter; monitorização da pressão intracraniana; e administração de medicamentos. Conclusões: a realização do scoping review permitiu identificar os principais cuidados de enfermagem direcionados ao paciente adulto submetido à colocação de derivação ventricular externa a partir das evidências disponíveis até o momento.

ABSTRACT Objectives: to map the available evidence about nursing care aimed at adult patients using external ventricular drain. Methods: this is a review using the scoping review method. Results: Initially, 965 studies were identified and, after the eligibility criteria, a sample of 54 publications was obtained. Each of them was assessed according to GRADE, resulting in three studies with high quality; 14 with moderate quality; 32 with low quality; and five with very low quality. It was highlighted 20 nursing care subdivided into nine categories, namely: drainage system; bed positioning and mobilization; catheter care; monitoring of intracranial pressure; and medication administration. Conclusions: the scoping review made it possible to identify the main nursing care directed to adult patients undergoing placement of external ventricular drain from the evidence available to date.

RESUMEN Objetivo: mapear la evidencia disponible sobre la atención de enfermería dirigida a pacientes adultos que usan derivación ventricular externa. Métodos: esta es una revisión que utiliza el método de scoping review. Resultados: inicialmente, se identificaron 965 estudios y, después de los criterios de elegibilidad, se obtuvo una muestra de 54 publicaciones. Cada uno de ellos fue evaluado según GRADE, lo que resultó en tres estudios con alta calidad; 14 con calidad moderada; 32 con baja calidad; y nueve con muy baja calidad. Hubo 20 cuidados de enfermería, divididos en nueve categorías, tales como: sistema de drenaje; posicionamiento y movilización de la cama; cuidado del catéter; monitorización de la presión intracraneal; y administración de medicamentos. Conclusiones: la revisión del alcance permitió la identificación de los principales cuidados de enfermería dirigidos a pacientes adultos sometidos a la colocación de un bypass ventricular externo con base en la evidencia disponible hasta el momento.

https://doi.org/10.1590/0034-7167-2019-0796 2048 downloads

IVIA - Ibero-American VLBI Initiative -Progress on the Brazilian side
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LEPINE, JACQUES R.D.

; RAULIN, JEAN PIERRE

; DOMINICI, TANIA

; CASTRO, CARLOS GUILLERMO G. DE

; ROIG, FERNANDO VIRGILIO

; WIERMANN, ANDRÉ

; FERNANDES, MARCELO BORGES

; HADANO, YASUCHI

; CORRERA, FATIMA SALETE

; BECCARO, WESLEY

; LUQUEZE, MARCOS AURELIO

; VERRI, ANTONIO SANDRO

; ZANELLA, DANILO CESAR

; MENÉNDEZ-DELMESTRE, KARIN

; GONÇALVES, THIAGO SIGNORINI

; ALMEIDA, ULISSES BARRES DE

; FIGUEREDO, MILITÃO VIEIRA

Anais da Academia Brasileira de Ciências

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2021, Volume 93 elocation e20201697

Abstract: En | Text: En | PDF: En

Abstract IVIA is a joint initiative of at least 8 Latin-American countries plus Portugal and Spain to make good use of large telecommunications antennas that are out of service in these countries, because most international communications are now using submarine cables. The first step will be to refurbish the antennas and then to start doing single dish observations of radiosources. In a second step the antennas will be equipped with VLBI (Very Long Base Interferometry) equipment, to establish a VLBI network. This project will be able to effectively promote scientific integration in Ibero-America. The work is starting in several countries; here we present several scientific cases for the use of the antennas, and we report on the first Brasilian activities.

https://doi.org/10.1590/0001-3765202120201697 132 downloads

Baryon Acoustic Oscillations from Integrated Neutral Gas Observations: an instrument to observe the 21cm hydrogen line in the redshift range 0.13 < z < 0.45 – status update
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WUENSCHE, CARLOS A.

; ABDALLA, ELCIO

; ABDALLA, FILIPE

; BAROSI, LUCIANO

; WANG, BIN

; AN, RUI

; BARRETOS, JOÃO A. M.

; BATTYE, RICHARD

; BRITO, FRANCISCO A.

; BROWNE, IAN

; CORREIA, DANIEL

; COSTA, ANDRÉ A.

; DELABROUILLE, JACQUES

; DICKINSON, CLIVE

; FENG, CHANG

; FERREIRA, ELISA G. M.

; FORNAZIER, KARIN

; DE GASPERIS, GIANCARLO

; GUTIERREZ, PRISCILA

; HARPER, STUART

; LANDIM, RICARDO G.

; LICCARDO, VINCENZO

; MA, YIN-ZHE

; MACHADO, TELMO

; MAFFEI, BRUNO

; MARINS, ALESSANDRO

; MENDES, MILENA M. M.

; MERICIA, EDUARDO

; MONSTEIN, CHRISTIAN

; MOTTA, PABLO

; NOVAES, CAMILA

; OTOBONE, CARLOS H.

; PEEL, MICHAEL

; QUEIROZ, AMILCAR R.

; RADCLIFFE, CHRISTOPHER

; REMAZEILLES, MATHIEU

; RIBEIRO, RAFAEL M. G.

; SANG, YU

; SANTOS, JULIANA F. R.

; SANTOS, LARISSA

; SANTOS, MARCELO. V.

; SHAN, CHENXI

; SILVA, GUSTAVO B.

; VIEIRA, FREDERICO

; VIEIRA, JORDANY

; VILLELA, THYRSO

; XIAO, LINFENG

; YANG, WEIQIANG

; ZHANG, JIAJUN

; ZHANG, XUE

; ZHU, ZENGHAO

Anais da Academia Brasileira de Ciências

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2021, Volume 93 elocation e20201096

Abstract: En | Text: En | PDF: En

Abstract BINGO (BAO from Integrated Neutral Gas Observations) is a unique radio telescope designed to map the intensity of neutral hydrogen distribution at cosmological distances, making the first detection of Baryon Acoustic Oscillations (BAO) in the frequency band 980 MHz - 1260 MHz, corresponding to a redshift range 0.127 < z < 0.449. BAO is one of the most powerful probes of cosmological parameters and BINGO was designed to detect the BAO signal to a level that makes it possible to put new constraints on the equation of state of dark energy. The telescope will be built in Paraíba, Brazil and consists of two \thicksim 40m mirrors, a feedhorn array of 50 horns, and no moving parts, working as a drift-scan instrument. It will cover a 15 ^{\circ} ∘ declination strip centered at \sim \delta ∼ δ =-15 ^{\circ} ∘, mapping \sim ∼ 5400 square degrees in the sky. The BINGO consortium is led by University of São Paulo with co-leadership at National Institute for Space Research and Campina Grande Federal University (Brazil). Telescope subsystems have already been fabricated and tested, and the dish and structure fabrication are expected to start in late 2020, as well as the road and terrain preparation.

https://doi.org/10.1590/0001-3765202120201096 413 downloads

Occurrence of the louse fly Ornithoctona erythrocephala Leach (1817) (Diptera: Hippoboscidae) on a free-living red-legged seriema (Cariama cristata)
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Silva, Thiago Merighi Vieira da

; Graciolli, Gustavo

; Santi, Mariele De

; Calchi, Ana Cláudia

; Machado, Ana Carolina de Queiroz

; Werther, Karin

; Machado, Rosangela Zacarias

; Barros-Battesti, Darci Moraes

; André, Marcos Rogério

Revista Brasileira de Parasitologia Veterinária

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2021, Volume 30 N. 2 elocation e025520

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste estudo foi descrever pela primeira vez a ocorrência da mosca Hippoboscidae Ornithoctona erythrocephala em uma seriema (Cariama cristata). Um espécime de díptero foi encontrado entre as penas de dessa ave, que havia sido encaminhada para necropsia ao Serviço de Patologia de Animais Selvagens, UNESP, Jaboticabal. A mosca foi armazenada em álcool absoluto e enviada ao Instituto de Biociências da Universidade Federal do Mato Grosso do Sul para identificação por um especialista. Baseado em características morfológicas, o espécime foi identificado como fêmea de Ornithoctona erythrocephala. Este relato oferece a descrição de um novo hospedeiro para O. erythrocephala.

Abstract The aim of this study was to report, for the first time, the occurrence of the hippoboscid fly Ornithoctona erythrocephala on a red-legged seriema (Cariama cristata). A Diptera specimen was found among the feathers of a free-living red-legged seriema, which was referred to necropsy at the Wild Animal Pathology Service, UNESP Jaboticabal. The fly was collected, stored in absolute alcohol, and shipped to the Institute of Biosciences of the Federal University of Mato Grosso do Sul for proper identification. Based on morphological characters, the specimen was identified as a female of Ornithoctona erythrocephala. This study provides a report on a new host for O. erythrocephala.

https://doi.org/10.1590/s1984-29612021030 136 downloads

Habitabilidade cósmica e a possibilidade de existência de vida em outros locais do universo
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Vieira, Frederico

; Machaieie, Dinelsa

; Fornazier, Karin

; Corazza, Lia

; Castro, Manuel

; Vilas-Boas, José Williams

; Cecatto, José Roberto

; Wuensche, Carlos Alexandre

Revista Brasileira de Ensino de Física

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2018, Volume 40 N. 4 elocation e4308

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Este artigo aborda alguns aspectos relacionados ao conceito de vida como a conhecemos e explora a relação entre a evolução química do Universo e a produção dos elementos básicos da química prebiótica. Baseando-se no Modelo Cosmológico Padrão, são descritas as condições cosmológicas que levaram ao surgimento desses elementos e são mostradas evidências de que o Universo, em seus estágios primordiais, dispunha de elementos capazes de produzir substâncias orgânicas. É feita uma breve abordagem de como a química em ambientes astrofísicos leva à formação de compostos que fazem parte da cadeia de reações que conduz à formação dos "tijolos da vida". Finalmente, levantamos a hipótese que o universo poderia ter zonas habitáveis a partir dos primeiros 30 milhões da anos e que a condição de habitabilidade tem estreita relação com a sua evolução química, mesmo quando se leva em consideração a hipótese de diferentes universos.

Abstract This article discusses some aspects related to the concept of life as we know it and explores the relationship between the chemical evolution of the Universe and the production of the basic elements of prebiotic chemistry. Based on the Standard Cosmological Model, the cosmological conditions that led to the appearance of these elements are described and evidences are shown that the Universe, in its primordial stages, had elements capable of producing organic substances. Next section gives a short overview on how chemistry in astrophysical environments leads to the formation of compounds that are part of the chain of reactions that leads to the formation of the "bricks of life." Finally, we mention that the universe could have habitable zones from the first 30 million years and that the habitability condition has a close relation with its chemical evolution, even when one takes into account the hypothesis of different universes.

https://doi.org/10.1590/1806-9126-rbef-2017-0325 4347 downloads

Considerations of potential vectors and animal reservoirs in an emerging cutaneous leishmaniasis area in São Domingos ranch, Paraná State in Southearn Brazil
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Membrive, Norberto Assis

; Hisatugo, Flora

; Silveira, Thaís Gomes Verzignassi

; Teixeira, Jorge Juarez Vieira

; Reinhold-Castro, Kárin Rosi

; Teodoro, Ueslei

Revista do Instituto de Medicina Tropical de São Paulo

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2017, Volume 59 elocation e64

Abstract: En | Text: En | PDF: En

ABSTRACT The aim of this study was to better understand the dynamics of Leishmania sand flies and reservoirs in São Domingos ranch, Arapongas municipality, Paraná State, an anthropic environment in an endemic area of cutaneous leishmaniasis (CL). Sand flies were collected in wild animal burrows, residences and in the forest, with Falcão light trap (FA), Shannon trap (SH) and quadrangular pyramidal trap (QP). The search for Leishmania was made on sand flies, biological samples of wild rodents and dogs using PCR and culture; while parasite direct search (DS) was carried out on animal skin lesions; infection of gold hamsters; and indirect immunofluorescence (IIF) test in dog blood samples. Eighty eight (88) sand flies were collected with FA traps and 526 sand flies using the SH trap, with a predominance of Pintomyia fischeri. Six hundred and one (601) specimens of Brumptomyia brumpti were collected in armadillo burrows, with the QP trap. Seventeen (17) wild rodents were captured, six of them had skin lesions with characteristics of Leishmania infection. Even though no positive test was found for Leishmania, epidemiological surveillance should be maintained, remembering that the human buildings are situated only 50 m from the forest. Considering the species of wild animals and sandflies found in São Domingos, the negative test found do not exclude the existence of the Leishmania transmission cycle in this preservation area.

https://doi.org/10.1590/s1678-9946201759064 1313 downloads

Genetic variability of populations of Nyssomyia neivai in the Northern State of Paraná, Brazil
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Gasparotto, Jaqueline de Carvalho

; Costa-Ribeiro, Magda Clara Vieira da

; Thomaz-Soccol, Vanete

; Liebel, Sandra Mara Rodrigues da Silva

; Neitzke-Abreu, Herintha Coeto

; Reinhold-Castro, Kárin Rosi

; Cristovão, Edilson Colhera

; Teodoro, Ueslei

Revista do Instituto de Medicina Tropical de São Paulo

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2017, Volume 59 elocation e10

Abstract: En | Text: En | PDF: En

ABSTRACT The genetic study of sandfly populations needs to be further explored given the importance of these insects for public health. Were sequenced the NDH4 mitochondrial gene from populations of Nyssomyia neivai from Doutor Camargo, Lobato, Japira, and Porto Rico, municipalities in the State of Paraná, Brazil, to understand the genetic structure and gene flow. Eighty specimens of Ny. Neivai were sequenced, 20 from each municipality, and 269 base pairs were obtained. A total of 27 haplotypes and 28 polymorphic sites were found, along with a haplotypic diversity of 0.80696 and a nucleotide diversity of 0.00567. Haplotype H5, with 33 specimens, was the most common among the four populations. Only haplotypes H5 and H7 were present in all four populations. The population from Doutor Camargo showed the highest genetic diversity, and only this population shared haplotypes with those from the other municipalities. The highest number of haplotypes was sheared with Lobato which also had the highest number of unique haplotypes. This probably occurred because of constant anthropic changes that happened in the environment during the first half of the twentieth century, mainly after 1998. There was no significant correlation between genetic and geographical distances regarding these populations. However, the highest genetic and geographical distances, and the lowest gene flow were observed between Japira and Porto Rico. Geographical distance is a possible barrier between these municipalities through the blocking of haplotype sharing.

https://doi.org/10.1590/s1678-9946201759010 1603 downloads

Disseminated cutaneous leishmaniasis caused by Leishmania braziliensis in Southern Brazil
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Membrive, Norberto Assis

; Kazuma, Flávio Jun

; Silveira, Thaís Gomes Verzignassi

; Teixeira, Jorge Juarez Vieira

; Reinhold-Castro, Kárin Rosi

; Teodoro, Ueslei

Revista do Instituto de Medicina Tropical de São Paulo

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2017, Volume 59 elocation e37

Abstract: En | Text: En | PDF: En

ABSTRACT The authors report a case of disseminated cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis, in a 55 years old patient with 1,119 lesions distributed throughout the body. The patient resides in Sabáudia municipality, North of Paraná State, Southern Brazil, where there was no previous report of this form of leishmaniasis. Treatment with meglumine antimoniate was successful, although the diagnosis was made only five months later.

https://doi.org/10.1590/s1678-9946201759037 2820 downloads

10.

Neurofibromatosis: part 2 – clinical management
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Batista, Pollyanna Barros

; Bertollo, Eny Maria Goloni

; Costa, Danielle de Souza

; Eliam, Lucas

; Cunha, Karin Soares Gonçalves

; Cunha-Melo, José Renan

; Darrigo Junior, Luiz Guilherme

; Geller, Mauro

; Gianordoli-Nascimento, Ingrid Faria

; Madeira, Luciana Gonçalves

; Mendes, Hérika Martins

; Miranda, Débora Marques de

; Mata-Machado, Nikolas Andre

; Morato, Eric Grossi

; Pavarino, Érika Cristina

; Pereira, Luciana Baptista

; Rezende, Nilton Alves de

; Rodrigues, Luíza de Oliveira

; Sette, Jorge Bezerra Cavalcanti

; Silva, Carla Menezes da

; Souza, Juliana Ferreira de

; Souza, Márcio Leandro Ribeiro de

; Martins, Aline Stangherlin

; Valadares, Eugênia Ribeiro

; Vidigal, Paula Vieira Teixeira

; Waisberg, Vanessa

; Waisberg, Yehuda

; Rodrigues, Luiz Oswaldo Carneiro

Arquivos de Neuro-Psiquiatria

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jun 2015, Volume 73 N. 6 Pages 531 - 543

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A primeira parte desta diretriz abordou o diagnóstico diferencial das neurofibromatoses (NF): neurofibromatose do tipo 1 (NF1), neurofibromatose do tipo 2 (NF2) e schwannomatose (SCH). As NF compartilham algumas características, como a origem neural dos tumores e sinais cutâneos, e afetam cerca de 80 mil brasileiros. O aumento do conhecimento científico sobre as NF tem permitido melhor manejo clínico e redução da morbidade das complicações, resultando em melhor qualidade de vida para os pacientes com NF. A maioria dos médicos é capaz de realizar o diagnóstico das NF, mas a variedade de manifestações clínicas e a dificuldade de se prever o surgimento e a gravidade de complicações, torna o manejo da NF um desafio para o clínico e envolve diferentes especialistas para o tratamento adequado e aconselhamento genético, especialmente a NF2 e a SCH. O presente texto sugere algumas orientações para o acompanhamento dos portadores de NF, com ênfase na NF1.

Part 1 of this guideline addressed the differential diagnosis of the neurofibromatoses (NF): neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH). NF shares some features such as the genetic origin of the neural tumors and cutaneous manifestations, and affects nearly 80 thousand Brazilians. Increasing scientific knowledge on NF has allowed better clinical management and reduced rate of complications and morbidity, resulting in higher quality of life for NF patients. Most medical doctors are able to perform NF diagnosis, but the wide range of clinical manifestations and the inability to predict the onset or severity of new features, consequences, or complications make NF management a real clinical challenge, requiring the support of different specialists for proper treatment and genetic counseling, especially in NF2 and SCH. The present text suggests guidelines for the clinical management of NF, with emphasis on NF1.

https://doi.org/10.1590/0004-282X20150042 13090 downloads

11.

Composição química e toxicidade de óleos essenciais para o pulgão-verde Schizaphis graminum(Rondani, 1852)
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Lima, Rafaela Karin

; Cardoso, Maria das Graças

; Moraes, Jair Campos

; Carvalho, Stephan Malfitano

; Melo, Bruno Almeida

; Vieira, Sara Silveira

Arquivos do Instituto Biológico

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mar 2014, Volume 81 N. 1 Pages 22 - 29

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este trabalho teve como objetivo identificar e quantificar os constituintes dos óleos essenciais de Illicum verum, Ageratum conyzoides,Piper hispidinervume Ocotea odorifera, bem como avaliar a toxicidade para o pulgão-verde Schizaphis graminum. A qualificação dos constituintes foi realizada por meio de um cromatógrafo gasoso + espectrômetro de massas, e a quantificação, por um cromatógrafo gasoso + detector de ionização de chama, ambos com uma coluna DB5. O método de hidrodestilação promoveu um rendimento (p/p) de 3,81% para I. verum, 0,46% para A. conyzoides, 2,85% para P. hispidinervume 0,68% para O. odorífera. Já os componentes majoritários foram: precoceno (87,0%) e (E)-cariofileno (7,1%) para A. conyzoides; (E)-anetol (90,4%), limoneno (2,6%) e metil-chavicol (1,3%) para I. verum; metil-eugenol (81,2%) e safrol (10,6%) para Ocotea odorífera; e safrol (82,5%) e α-terpinoleno (13,4%) para P. hispidinervum. Pelos testes de toxicidade aguda (24 horas) com folhas de sorgo ou papel-filtro contaminados, verificou-se que o óleo de A. conyzoides foi o mais tóxico para o pulgão, com CL50de 7,13 e 7,08 µL óleo/cm2 respectivamente, seguido por O. odorifera com CL50 de 11,80 e 103,00 µL óleo/cm2 respectivamente; I. verum de 51,80 µL óleo/cm2 em ambos os substratos; e o menos tóxico foi o óleo essencial de P. hispidinervum, com CL50 de 62,50 e 143,00 µL óleo/cm2, respectivamente. Dessa maneira, sugere-se que o uso dos óleos essenciais pode representar uma nova ferramenta em programas de manejo integrado de pragas.

The aim of this study was to assess the chemical composition of essential oils of Illicum verum, Ageratum conyzoides,Piper hispidinervumand Ocotea odorífera, as well as their toxicity to the green-aphid Schizaphis graminum. Compound identification was carried out with gas chromatography + mass spectrometry, and quantification with gas chromatography + flame ionization detector, both with DB5 column. The hydrodistillation process promoted oil yield of 3.81% for I. verum; 0.46% for A. conyzoides; 2.85 % for P. hispidinervum;and 0.68 % for O. odorífera. The major components from the oils of A. conyzoides was precocene (87.0%) and (E)-caryophyllene (7.1%); (E)-anethol (90.4%), limonene (2.6%) and methyl-chavicol (1.3%) for I. verum; methyleugenol (81.2%) and safrole (10.6%) for O. odorifera; and safrole (82.5%) and α-terpinolene (13.4%) for P. hispidinervum. The acute toxicity test (24 hours) performed by contact in sorghum leaves or contaminated filter-paper showed that the higher toxicity occur with essential oils of A. conyzoides, with LC50of 7.01 and 7.01 µg oil/cm2, respectively; followed by O. odorifera, with LC50 of 17.10 and 66.70 µg oil/cm2, respectively; I. verum, with LC50of 66.40 and 65.40 µg oil/cm2, respectively; and low toxicity was observed for the P. hispidinervum essential oil, with LC50 of 64.00 and 143.00 oil/cm2, respectively. With the results obtained in this research, we can state that the use of these essential oils can be a new tool in integrated pest management.

https://doi.org/10.1590/S1808-16572014000100005 4761 downloads

12.

Neurofibromatoses: part 1 ? diagnosis and differential diagnosis
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Rodrigues, Luiz Oswaldo Carneiro

; Batista, Pollyanna Barros

; Goloni-Bertollo, Eny Maria

; Souza-Costa, Danielle de

; Eliam, Lucas

; Eliam, Miguel

; Cunha, Karin Soares Gonçalves

; Darrigo Junior, Luiz Guilherme

; Ferraz Filho, José Roberto Lopes

; Geller, Mauro

; Gianordoli-Nascimento, Ingrid F.

; Madeira, Luciana Gonçalves

; Malloy-Diniz, Leandro Fernandes

; Mendes, Hérika Martins

; Miranda, Débora Marques de

; Pavarino, Erika Cristina

; Baptista-Pereira, Luciana

; Rezende, Nilton A.

; Rodrigues, Luíza de Oliveira

; Silva, Carla Menezes da

; Souza, Juliana Ferreira de

; Souza, Márcio Leandro Ribeiro de

; Stangherlin, Aline

; Valadares, Eugênia Ribeiro

; Vidigal, Paula Vieira Teixeira

Arquivos de Neuro-Psiquiatria

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mar 2014, Volume 72 N. 3 Pages 241 - 250

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Neurofibromatoses (NF) constituem um grupo de doenças genéticas com predisposição ao crescimento de múltiplos tumores: tipo 1 (NF1), tipo 2 (NF2) e schwannomatose (SCH). Estas doenças têm em comum a origem neural dos tumores e os sinais cutâneos. Afetam cerca de 80 mil brasileiros. O maior conhecimento científico sobre as NF tem permitido melhor manejo clínico, redução da morbidade das complicações e melhor qualidade de vida. Na maioria dos casos, os especialistas em neurologia, dermatologia, genética clínica, oncologia e medicina interna estão capacitados a realizar o diagnóstico diferencial e identificar suas principais complicações. Devido à sua variabilidade fenotípica, curso progressivo, multiplicidade de órgãos acometidos e evolução imprevisível, as NF frequentemente necessitam de especialistas em NF para o acompanhamento. A Parte 1 deste texto oferece orientações para o diagnóstico de cada tipo de NF e discute os diagnósticos diferenciais com outras doenças. A Parte 2 oferecerá orientações em relação ao manejo clínico das NF.

Neurofibromatoses (NF) are a group of genetic multiple tumor growing predisposition diseases: neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH), which have in common the neural origin of tumors and cutaneous signs. They affect nearly 80 thousand of Brazilians. In recent years, the increased scientific knowledge on NF has allowed better clinical management and reduced complication morbidity, resulting in higher quality of life for NF patients. In most cases, neurology, psychiatry, dermatology, clinical geneticists, oncology and internal medicine specialists are able to make the differential diagnosis between NF and other diseases and to identify major NF complications. Nevertheless, due to its great variability in phenotype expression, progressive course, multiple organs involvement and unpredictable natural evolution, NF often requires the support of neurofibromatoses specialists for proper treatment and genetic counseling. This Part 1 offers step-by-step guidelines for NF differential diagnosis. Part 2 will present the NF clinical management.

https://doi.org/10.1590/0004-282X20130241 22696 downloads

13.

Avaliação comportamental do processamento auditivo em indivíduos pós - traumatismo cranioencefálico: estudo piloto
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Santos, Renata Beatriz Fernandes

; Marangoni, Andréa Tortosa

; Andrade, Adriana Neves de

; Vieira, Marilena Manno

; Ortiz, Karin Zazo

; Gil, Daniela

Revista CEFAC

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oct 2013, Volume 15 N. 5 Pages 1156 - 1162

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: verificar o desempenho de indivíduos pós-traumatismo cranioencefálico em testes comportamentais para avaliação do processamento auditivo. MÉTODO: participaram da pesquisa 10 indivíduos audiologicamente normais com histórico de trauma craniano. Foram submetidos a: audiometria tonal liminar, logoaudiometria, medidas de imitância acústica (timpanometria e pesquisa dos reflexos acústicos) e avaliação comportamental do processamento auditivo (Testes de Localização Sonora, Memória Sequencial Verbal, Memória Sequencial Não Verbal, Padrão de Duração, Dicótico Consoante-Vogal, Dicótico de Dissílabos Alternados, Identificação de Sentenças Sintéticas com mensagem competitiva, Identificação de Intervalo Aleatório, Índice Percentual de Reconhecimento de Fala com gravação, Fala com Ruído Branco). RESULTADOS: o teste de Padrão de Duração indicou o teste com o maior número de alteração (60%). O teste com a média mais satisfatória foi o Índice Percentual de Reconhecimento de Fala com gravação (93%) e a média menos satisfatória relacionou-se ao teste Dicótico Consoante-Vogal, com 40,56%. As inversões (70%) representaram a tendência de erros no Dicótico de Dissílabos Alternados mais frequente. O processo gnósico do tipo decodificação foi o mais predominante (100%), seguido da organização (90%), não verbal (60%), codificação-perda gradual de memória (20%). Não houve alteração no processo gnósico de codificação-integração. CONCLUSÃO: os indivíduos pós-traumatismo cranioencefálico apresentam transtorno do processamento auditivo de diferentes graus, envolvendo os processos gnósicos de decodificação e organização.

PURPOSE: to characterize the performance of individuals after traumatic brain injury in behavioral tests to evaluate auditory processing. METHOD: the participants of this research were 10 individuals with normal hearing with traumatic brain injury. They were submitted to: pure tone audiometry, speech audiometry, acoustic immittance measures (tympanometry and acoustic reflex) and behavioral evaluation of auditory processing (Sound Location Test, Verbal Sequential Memory, Non Verbal Sequential Memory, Duration Pattern Sequence Test, Dichotic Consonant-vowel, Staggered Spondaic Word (Portuguese version), Identification of synthetic sentences with competitive message, Random Gap Detection Test, Percentage Index of Speech Recognition with recording, speech test). RESULTS: the test of Duration Pattern indicated the test with the largest number of alteration (60%). The test with the most satisfactory average was the Percentage Index of Speech Recognition with recording (93%) and the less satisfactory average test was related to dichotic consonant-vowel (40,56%). The reversals (70%) represented the tendency of more frequent errors in the SSW. The damage of decoding was the most prevalent (100%), followed by the organization (90%), supra-segmental (60%) and encoding-gradual loss of memory (20%). There was no damage of encoding-integration. CONCLUSIONS: the patients after traumatic brain injury present auditory processing disorders of varying degrees, involving the processes of decoding and organization.

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14.

Normas brasileiras para o Affective Norms for English Words
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Kristensen, Christian Haag

; Gomes, Carlos Falcão de Azevedo

; Justo, Alice Reuwsaat

; Vieira, Karin

Trends in Psychiatry and Psychotherapy

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2011, Volume 33 N. 3 Pages 135 - 146

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: O presente estudo realizou a tradução e adaptação do Affective Norms for English Words (ANEW) para o português brasileiro (ANEW-Br) e obteve medidas de emocionalidade para um conjunto de 1.046 palavras em português. MÉTODO: Uma amostra de 755 universitários de ambos os sexos utilizou as escalas de valência e alerta do Self-Assessment Manikin para julgar a emocionalidade de 1.046 palavras em português. RESULTADOS: Os valores de valência ficaram no intervalo de 1,16 a 8,80, enquanto que os valores de alerta ficaram no intervalo de 2,22 a 7,67. Análises adicionais indicaram que as medidas de valência e alerta se mostraram fidedignas, além de sugerir adequação do método utilizado para coleta das medidas de emocionalidade. CONCLUSÃO: A disponibilização das normas brasileiras para o ANEW representa um avanço metodológico para pesquisadores brasileiros no desenvolvimento de futuros estudos sobre os efeitos da emoção na cognição humana.

INTRODUCTION: The present study translated and adapted the Affective Norms for English Words (ANEW) to Brazilian Portuguese (ANEW-Br) and collected emotionality measures for a set of 1,046 words in Brazilian Portuguese. METHOD: A sample of 755 male and female undergraduate students used the valence and arousal scales of the Self-Assessment Manikin to judge the emotionality of 1,046 words in Brazilian Portuguese. RESULTS: Valence values ranged from 1.16 to 8.80, while arousal values ranged from 2.22 to 7.67. Further analyses indicated that both valence and arousal measures were reliable and suggested that the method used was appropriate for the collection of emotionality measures. CONCLUSION: The availability of Brazilian norms for the ANEW represents a methodological advancement for Brazilian investigators in the development of future studies about the effects of emotion on human cognition.

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15.

Neuropsychological aspects of psychogenic nonepileptic seizures
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Portuguez, Mirna Wetters

; Costa, Danielle Irigoyen da

; Marroni, Sabine Possa

; Pagliarini, Vanessa

; Vieira, Karin

Journal of Epilepsy and Clinical Neurophysiology

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dec 2007, Volume 13 N. 4 Pages 24 - 27

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Crises não-epilépticas psicogênicas podem ser definidas como episódios de alterações paroxísticas no comportamento, similares a crises epilépticas, porém não associadas a alterações quantificáveis da atividade elétrica cerebral. No Programa de Cirurgia de Epilepsia do Hospital São Lucas da PUCRS estudamos 52 indivíduos (37 mulheres e 15 homens) com o diagnóstico de CNEP, associadas (57%) ou não (23%) a epilepsia refratária. Aspectos psicológicos nesta população incluíram abuso emocional (100%), abuso físico (80%), negligência física (70%), abuso sexual (30%), desordens de humor (40%) e ansiedade (50%). O impacto médico e psicossocial deste diagnóstico é elevado, fazendo contraponto a carência de serviços especializados em seu tratamento. Múltiplos procedimentos diagnósticos e terapêuticos e a participação de um time multiprofissional â€“ onde a neuropsicologia representa o elo natural entre a psicopatologia e o cérebro â€“ são necessários para o melhor atendimento a estes pacientes.

Psychogenic nonepileptic seizures (PNES) may be defined as paroxysmal changes in behavior that are similar to epileptic seizures but are not associated with quantifiable alterations in the electrical activity of the brain. At the Epilepsy Surgery Program (ESP) of the São Lucas Hospital at PUCRS (HSL-PUCRS), we studied 52 individuals (37 females and 15 males) with a diagnosis of PNES, associated (57%) or not (23%) with refractory epileptic seizures. We found emotional abuse (100%), physical abuse (80%), emotional neglect (80%), physical negligence (70%) and sexual abuse (30%), mood (40%) and anxiety disorders (50%), as the main psychological components in such population. Although the medical and psychosocial impact of PNES can be estimated as significant, the absence of specialized services for its treatment is striking. Multiple diagnostic and therapeutic procedures and the participation of a specialized multidisciplinary team â€“ where neuropsychology functions as a link between the mental processes/psychopathologies and the brain â€“ are required to ensure proper management of such cases.

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