Search | SciELO

Resumo A fração solúvel de petróleo (WSF) prejudica os organismos, porém os danos podem variar entre os níveis celular e tecidual. O objetivo do presente estudo foi avaliar o efeito agudo (24 h, 48 h e 72 h) e subcrônico (36 dias) da WSF (0%, 25% e 100%) em juvenis do peixe neotropical predador topo Hoplias aff. malabaricus. Os efeitos da WSF foram avaliados no nível molecular utilizando o ensaio do cometa e o teste do micronúcleo para o dano genômico e no nível morfológico através da identificação histológica de lesões patológicas no fígado. Em ambas exposições (aguda e subcrônica) encontramos baixos níveis de dano no DNA (< 10% de DNA na cauda do cometa) e frequência de micronúcleos não significativa em peixes expostos a WSF. As lesões mais significativas no fígado dos peixes expostos a WSF foram a vacuolização lipídica, hipertrofia e focos de necroses. Como estas lesões foram progressivas e persistentes, sua irreversibilidade pode afetar negativamente o recrutamento dos peixes, mesmo sendo um predador topo resistente.

Abstract Petroleum water soluble fraction (WSF) impairs organisms, but damages may vary among cell and tissue levels. The aim of the present study was to evaluate the acute (24 h, 48 h, 72 h) and subchronic effects (36 days) of WSF (0%, 25% and 100%) in juveniles of the Neotropical top predator fish Hoplias aff. malabaricus. The effects of WSF were evaluated at a molecular level using the comet assay and micronucleus test for genome damage; and at a morphological level through histological identification of liver pathologic lesions. In both acute and subchronic exposure we found low levels of DNA damage (< 10% of comet tail) and non-significant frequency of micronucleus in WSF exposed fish. The most significant liver lesions in WSF exposed fish were fatty vacuolization, hypertrophy and focal necrosis. Since these tissue injuries were progressive and persistent, their irreversibility may negatively affect fish recruitment, even in a such resistant top predator.

https://doi.org/10.1590/1519-6984.253731

A preliminary approach to embryonic development of Austrolebias wolterstorffi, an endangered neotropical annual fish species
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Weber, V.

; Godoy, R. S.

; Hoffmann, P. H. O.

; Lanés, L. E. K.

; Volcan, M.

; Maltchik, L.

Brazilian Journal of Biology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2023, Volume 83 elocation e271218

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Annual fish live exclusively in temporary wetlands and are among the shortest-lived vertebrates in the world. These fish persist in these habitats due to drought-resistant eggs, that which, through diapauses are able to detect stimuli from the environment to start the development processes. They are also able to direct their embryonic development in different trajectories with different development times. Our objective in this paper was to describe the different stages of embryonic development of Austrolebias wolterstorffi, a critically endangered annual fish. A total of 27 stages of embryonic development were identified for the two observed developmental pathways (direct and diapause 2). Of these 27 developmental stages observed, 24 were identical between the two types of trajectories and three different. A total of 90% of the embryos that completed their development proceeded normally, without pauses. One embryo had a different development from the others, entering diapause 2, with a pause in development for 48 h. Although the embryonic development of A. wolterstorffi is similar to that of other Neotropical annual fish species, the diapause 2 occurs when the embryo has a large body size and a well-developed brain, indicating that the lack of embryonic information of the genus Austrolebias may hide characteristics still undescribed or even different survival strategies than what has been observed for other annual fish.

Resumo Os peixes anuais vivem exclusivamente em áreas úmidas temporárias e estão entre os vertebrados de vida mais curta do mundo. Esses peixes persistem nesses habitats devido a ovos resistentes à seca, que, por meio de diapausas, são capazes de detectar estímulos do ambiente para iniciar os processos de desenvolvimento embrionário. Eles também são capazes de direcionar seu desenvolvimento embrionário em diferentes trajetórias com diferentes tempos de desenvolvimento. O objetivo deste trabalho foi descrever os diferentes estágios do desenvolvimento embrionário de Austrolebias wolterstorffi, um peixe anual criticamente ameaçado. Um total de 27 estágios de desenvolvimento embrionário foram identificados para as duas trajetórias de desenvolvimento observadas (direto e diapausa 2). Desses 27 estágios de desenvolvimento observados, 24 eram idênticos entre os dois tipos de trajetórias e três diferentes. Um total de 90% dos embriões que completaram seu desenvolvimento seguiu normalmente, sem pausas. Um embrião teve um desenvolvimento diferente dos demais, entrando na diapausa 2, com pausa no desenvolvimento de 48h. Embora o desenvolvimento embrionário de A. wolterstorffi seja semelhante ao de outras espécies de peixes anuais neotropicais, a diapausa 2 ocorre quando o embrião tem um corpo grande e um cérebro bem desenvolvido, indicando que a falta de informação embrionária do gênero Austrolebias pode escondem características ainda não descritas ou mesmo estratégias de sobrevivência diferentes das observadas para outros peixes anuais.

https://doi.org/10.1590/1519-6984.271218

Hacia una formación inicial docente con pertinencia cultural y social: lecciones desde las ideologías curriculares de futuros profesores
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Peña-Sandoval, César H.

; Venegas-Weber, Patricia

Formación universitaria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2022, Volume 15 N. 5 Pages 87 - 98

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: This study aimed to identify the predominant curriculum ideologies among preservice teachers at Chilean universities, analyzing the formative potential that this knowledge has for teacher education. Enacting a FONDECYT project, information was collected using the Inventory of Curriculum Ideologies, which was answered by 433 participants from four universities located in different Chilean regions. Curriculum ideologies, a sociocultural perspective, and a social justice approach were used as theoretical lenses. The results showed that the predominant ideology was learner-centered and, in concomitance with social reconstructionism, enabled ideological hybridity. Also relevant was the presence of eclecticism and, to a lesser extent, anti-academicism. These results fostered emerging concepts such as critical-reflexive hybridity, promoting curricular enrichment in teacher education. The conclusions point to greater social and cultural relevance to serve disadvantaged students in the school system.

Resumen: Este estudio se propuso identificar las ideologías curriculares predominantes entre profesoras y profesoras en formación de universidades chilenas, analizando el potencial formador que este conocimiento tiene para la FID (formación inicial docente). En el marco de un proyecto FONDECYT, se recolecta información utilizando el denominado Inventario de Ideologías Curriculares. Este fue respondido por 433 participantes provenientes de cuatro universidades de distintas regiones de Chile. El análisis tuvo como lentes teóricos las ideologías curriculares, la perspectiva sociocultural y el enfoque de justicia. Los resultados mostraron que la ideología predominante fue la centrada en el aprendizaje y, en concomitancia con el reconstruccionismo social, posibilita la hibridez ideológica. También fue relevante la presencia del eclecticismo y, en menor medida, el antiacademicismo. Estos resultados impulsaron conceptos emergentes como la hibridez crítico-reflexiva, promoviendo el enriquecimiento curricular en la FID. Las conclusiones apuntan a mayor pertinencia social y cultural al servicio de las y los estudiantes menos favorecidos del sistema escolar.

9 downloads

Molecular and morphometric analysis of nominal Brachidontes exustus (Mollusca, Mytilidae) in Brazilian waters
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Quintanilha, David B.

; Fernandes, Flavio C.

; Guerra, Caroline R.

; Campos, Savio H. C.

; Weber, Laura I.

Genetics and Molecular Biology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2022, Volume 45 N. 2 elocation e20210247

Abstract: En | Text: En | PDF: En

Abstract Brachidontes exustus (Mollusca, Mytilidae) is mainly distributed in Central America, where it has been recognized as a _lataforma species. This study aimed to determine whether B. exustus extends beyond the Amazon Barrier and southward along the Brazilian West Atlantic coast. Mitochondrial genes coding for cytochrome-c oxidase, subunit I (COI) and 16S subunit of ribosomal _lataforma__ cid (16S rRNA) were analyzed with _lata parameters on Brazilian populations (Salvador, Arraial do Cabo and Fernando de Noronha) of scorched mussels previously recorded as B. exustus. Multivariate morphometric _latafor showed partial discrimination of species. Molecular _latafor confirmed B. exustus at Salvador, a population highly similar to Cartagena (Colombia), both belonging to the Atlantic Clade of the B. exustus complex. This fact adds evidence to the idea of the Amazon outflow as a semipermeable barrier. In the southeast of Brazil, B. exustus was not found; instead, B. darwinianus is the species represented at Arraial do Cabo (state of Rio de Janeiro), associated with brackish _lataf. Scorched mussels from Fernando de Noronha are most closely related to B. puniceus from Cape Verde with 4.4% differentiation. Demonstrating an independent evolutionary history since at least the beginning of the Pleistocene, its proposed new name is B. noronhensis.

https://doi.org/10.1590/1678-4685-gmb-2021-0247

COVID-19: The question of genetic diversity and therapeutic intervention approaches
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Figueiredo, David Livingstone Alves

; Ximenez, João Paulo Bianchi

; Seiva, Fábio Rodrigues Ferreira

; Panis, Carolina

; Bezerra, Rafael dos Santos

; Ferrasa, Adriano

; Cecchini, Alessandra Lourenço

; Medeiros, Alexandra Ivo de

; Almeida, Ana Marisa Fusco

; Ramão, Anelisa

; Boldt, Angelica Beate Winter

; Moya, Carla Fredrichsen

; Chin, Chung Man

; Paula, Daniel de

; Rech, Daniel

; Gradia, Daniela Fiori

; Malheiros, Danielle

; Venturini, Danielle

; Tavares, Eliandro Reis

; Carraro, Emerson

; Ribeiro, Enilze Maria de Souza Fonseca

; Pereira, Evani Marques

; Tuon, Felipe Francisco

; Follador, Franciele Aní Caovilla

; Fernandes, Glaura Scantamburlo Alves

; Volpato, Hélito

; Cólus, Ilce Mara de Syllos

; Oliveira, Jaqueline Carvalho de

; Rodrigues, Jean Henrique da Silva

; Santos, Jean Leandro dos

; Visentainer, Jeane Eliete Laguila

; Brandi, Juliana Cristina

; Serpeloni, Juliana Mara

; Bonini, Juliana Sartori

; Oliveira, Karen Brajão de

; Fiorentin, Karine

; Lucio, Léia Carolina

; Faccin-Galhardi, Ligia Carla

; Ferreto, Lirane Elize Defante

; Lioni, Lucy Megumi Yamauchi

; Consolaro, Marcia Edilaine Lopes

; Vicari, Marcelo Ricardo

; Arbex, Marcos Abdo

; Pileggi, Marcos

; Watanabe, Maria Angelica Ehara

; Costa, Maria Antônia Ramos

; Giannini, Maria José S. Mendes

; Amarante, Marla Karine

; Khalil, Najeh Maissar

; Lima Neto, Quirino Alves de

; Herai, Roberto H.

; Guembarovski, Roberta Losi

; Shinsato, Rogério N.

; Mainardes, Rubiana Mara

; Giuliatti, Silvana

; Yamada-Ogatta, Sueli Fumie

; Gerber, Viviane Knuppel de Quadros

; Pavanelli, Wander Rogério

; Silva, Weber Claudio da

; Petzl-Erler, Maria Luiza

; Valente, Valeria

; Soares, Christiane Pienna

; Cavalli, Luciane Regina

; Silva Jr, Wilson Araujo

Genetics and Molecular Biology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2021, Volume 44 N. 1 elocation e20200452

Abstract: En | Text: En | PDF: En

Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), is the largest pandemic in modern history with very high infection rates and considerable mortality. The disease, which emerged in China’s Wuhan province, had its first reported case on December 29, 2019, and spread rapidly worldwide. On March 11, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic and global health emergency. Since the outbreak, efforts to develop COVID-19 vaccines, engineer new drugs, and evaluate existing ones for drug repurposing have been intensively undertaken to find ways to control this pandemic. COVID-19 therapeutic strategies aim to impair molecular pathways involved in the virus entrance and replication or interfere in the patients’ overreaction and immunopathology. Moreover, nanotechnology could be an approach to boost the activity of new drugs. Several COVID-19 vaccine candidates have received emergency-use or full authorization in one or more countries, and others are being developed and tested. This review assesses the different strategies currently proposed to control COVID-19 and the issues or limitations imposed on some approaches by the human and viral genetic variability.

https://doi.org/10.1590/1678-4685-gmb-2020-0452

N-Alkylated Sulfamic Acid Derivatives as Organocatalyst in Multicomponent Synthesis of Fatty Dihydropyrimidinones
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Hack, Carolina R. L.

; Porciuncula, Larissa

; Weber, Andressa C. H.

; D’Oca, Caroline R. M.

; Russowsky, Dennis

; Moura, Jaqueline M.

; Pinto, Luiz A. A.

; D’Oca, Marcelo G. M.

Journal of the Brazilian Chemical Society

Journal Metrics
- Sobre o periódico
- SciELO Analytics

nov 2018, Volume 29 N. 11 Pages 2342 - 2349

Abstract: En | Text: En | PDF: En

In this work, N-alkylated sulfamic acid derivatives are introduced as promising acidic organocatalysts with convenient acidity and easy synthesis. The new organocatalysts derived from different nitrogenated compounds (amines, chitosan, urea and thiourea) were applied in multicomponent reactions to synthesize several dihydropyrimidinones (DHPMs). All tested organocatalysts resulted in good DHPM yields, using classic 1,3-dicarbonyl compounds and long-chain 1,3-dicarbonyl derivatives, demonstrating catalytic efficiency. N-Alkylated sulfamic acid derived from benzylamine showed good results (ca. 80% yields). In addition, excellent results were obtained with organocatalysts based on sulfamic acid and thiourea (ca. 80-97% yields), demonstrating the catalytic efficiency of new derivatives of thiourea organosulfamic catalysts.

https://doi.org/10.21577/0103-5053.20180112 1019 downloads

An Active Search Method for Finding Objects with Near-Optimal Property Values within a Given Set
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Matta, Cláudia E. da

; Paiva, Henrique M.

; Galvão, Roberto K. H.

; Araújo, Mário C. U.

; Soares, Sófacles F. C.

; Weber, Karen C.

; Pinto, Luiz A.

Journal of the Brazilian Chemical Society

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2016, Volume 27 N. 7 Pages 1177 - 1187

Abstract: En | Text: En | PDF: En

This paper proposes an active search method aimed at finding objects with optimal or near-optimal y-property values, on the basis of x-variables obtained by indirect, less costly methods. The proposed method progresses in a sequential manner, starting from a small subset of objects with known y-values. At each iteration, the K-nearest neighbour regression technique is employed to obtain estimates ŷ for the objects with unknown y-values. The object with best ŷ value is then subjected to a direct analysis procedure for evaluation of the y-property. Examples are presented with simulated data, as well as actual quantitative structure-activity relationship (QSAR) and near-infrared (NIR) spectrometry datasets. The QSAR and NIR case studies involve the search for maximal antidepressant activity in a set of arylpiperazine compounds and maximal pulp yield in a set of eucalyptus wood samples, respectively. In all these cases, the active search yielded results closer to the maximal y-value compared to the classical Kennard-Stone algorithm for object selection.

https://doi.org/10.5935/0103-5053.20160014 931 downloads

Effects of water-soluble fraction of petroleum on growth and prey consumption of juvenile Hoplias aff. malabaricus (Osteichthyes: Erythrinidae)
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Santos, R. M.

; Weber, L.

; Souza, V. L.

; Soares, A. R.

; Petry, A. C.

Brazilian Journal of Biology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

feb 2016, Volume 76 N. 1 Pages 10 - 17

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A influência da fração solúvel de petróleo (FSP) no consumo de presas e crescimento de juvenis da traíra Hoplias aff. malabaricus foi investigada. Os juvenis foram submetidos aos tratamentos FSP e Controle durante 28 dias, e adultos de matogrosso Hyphessobrycon eques foram oferecidos diariamente como presa para cada predador. O total de presas consumidas variou de 16 a 86 indivíduos. Apesar do menor consumo inicial de presas sob exposição de FSP, não houve diferenças significativas nas taxas de consumo entre os dois tratamentos. A FSP teve um efeito negativo no crescimento em tamanho de juvenis de H. aff. malabaricus. Embora a ausência de efeito no consumo de presas sugira uma relativa resistência de H. aff. malabaricus à exposição à FSP, o menor crescimento em tamanho dos indivíduos expostos ao poluente reflete possivelmente custos metabólicos. As implicações dos principais resultados nos níveis do organismo e da cadeia alimentar são discutidos, incluindo aspectos comportamentais e o papel desempenhado por este predador em ecossistemas aquáticos rasos.

Abstract The influence of the water-soluble fraction of petroleum (WSF) on prey consumption and growth of juvenile trahira Hoplias aff. malabaricus was investigated. Juveniles were submitted to either WSF or Control treatment over 28 days, and jewel tetra Hyphessobrycon eques adults were offered daily as prey for each predator. Total prey consumption ranged from 16 to 86 individuals. Despite the initially lower prey consumption under WSF exposure, there were no significant differences in overall feeding rates between the two treatments. Water-soluble fraction of petroleum had a negative effect on the growth in length of H. aff. malabaricus juveniles. Although unaffected, prey consumption suggested a relative resistance in H. aff. malabaricus to WSF exposition and the lower growth of individuals exposed to WSF than the Control possibly reflects metabolic costs. The implications of the main findings for the individual and the food chain are discussed, including behavioral aspects and the role played by this predator in shallow aquatic systems.

https://doi.org/10.1590/1519-6984.06714 1763 downloads

Phytochemical analysis of Vernonanthura tweedieana and a validated UPLC-PDA method for the quantification of eriodictyol
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Layzon Antonio Lemos da

; Faqueti, Larissa Gabriela

; Reginatto, Flávio Henrique

; Santos, Alan Diego Conceição dos

; Barison, Andersson

; Biavatti, Maique Weber

Revista Brasileira de Farmacognosia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

aug 2015, Volume 25 N. 4 Pages 375 - 381

Abstract: En | Text: En | PDF: En

AbstractVernonanthura tweedieana (Baker) H. Rob., Asteraceae, is used in the Brazilian folk medicine for the treatment of respiratory diseases. In this work the phytochemical investigation of its ethanol extracts as well as the development and validation of an UPLC-PDA method for the quantification of the eriodictyol from the leaves were performed. The phytochemical study for this species lead to the identification of ethyl caffeate, naringenin and chrysoeriol in mixture, eriodictyol from leaves, and the mixture of 3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-propan-1-one and evofolin B, apigenin, the mixture of caffeic and protocatechuic acid and luteolin from stems with roots, being reported for the first time for V. tweedieana, except for eriodictyol. The structural elucidation of all isolated compounds was achieved by 1H and 2D NMR spectroscopy, and in comparison with published data. An UPLC-PDA method for quantification of the eriodictyol in leaves of V. tweedieana was developed and validated for specificity, linearity, precision (repeatability and intermediate precision), limit of detection (LOD) and limit of quantification (LOQ), accuracy and robustness. In this study, an excellent linearity was obtained (r2 = 0.9999), good precision (repeatability RSD = 2% and intermediate precision RSD = 8%) and accuracy (average recovery from 98.6% to 99.7%). The content of eriodictyol in the extract of leaves of V. tweedieana was 41.40 ± 0.13 mg/g. Thus, this study allowed the optimization of a simple, fast and validated UPLC-PDA method which can be used to support the quality assessment of this herbal material.

https://doi.org/10.1016/j.bjp.2015.07.009 1769 downloads

10.

Linked Micromap Plots for South America -- General Design Considerations and Specific Adjustments
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

SYMANZIK, JÜRGEN

; DAI, XIAOTIAN

; WEBER, MARC H.

; PAYTON, QUINN

; MCMANUS, MICHAEL G.

Revista Colombiana de Estadística

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2014, Volume 37 N. 2 Pages 451 - 469

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Las gráficas de micromapas enlazados (LM por sus siglas en inglés) han sido usados en Estados Unidos desde su introducción en 1996 como una forma efectiva de presentar resúmenes estadísticos asociados con unidades espaciales regionales. Sin embargo, las gráficas LM son difíciles de crear por no expertos. La introducción al paquete R micromap ha simplificado la contrucción de gráficos LM para regiones geográficas arbitrarias al facilitar el uso de Sistemas de Información Geográficos (GIS por sus siglas en inglés) como la base para los mapas. En este artículo, se presentan gráficos LM para los países de Suramérica. Sin embargo, las representaciones espaciales están a menudo no disponibles para los gráficos LM, incluso después de simplificaciones automatizadas de los límites de las regiones. Un problema comón es que regiones geográficamente pequeñas a menuso no son visibles en los gráficos LM. Entonces, se hace necesario ampliar estas regiones pequeñas y mostrarlas por fuera del mapa principal. Se introducen algunas guías algoritmicas de cómo considerar regiones pequeñas en los gráficos LM de Suramérica. Adicionalmente, se dan recomendaciones de cómo incluir áreas que se encuentran lejanas de la principal región geográfica en los graficos LM.

Linked micromap (LM) plots have been in use in the United States of America (USA) since their introduction in 1996 as an effective way to display statistical summaries associated with regional spatial units. However, LM plots were always hard to create by non--experts. The introduction of the {\it micromap} R package has simplified the construction of LM plots for arbitrary geographic regions by facilitating the use of external Geographic Information System (GIS) features (such as shapefiles) as the basis for the maps. In this article, we will introduce LM plots for countries from South America. However, spatial representations of features are often not immediately suitable for LM plots, even after some automated simplification of the boundaries of the map regions. A common problem is that relatively small geographic regions are often not visible when plotted in LM plots. Thus, it is necessary to enlarge small regions and display them on the outside of the main map. We introduce some algorithmic guidelines on how small regions can be addressed in LM plots for South America. Moreover, we will provide recommendations how to include areas into LM plots that are far away from the main geographic region.

https://doi.org/10.15446/rce.v37n2spe.47949 1928 downloads

11.

The five-point Likert scale for dyspnea can properly assess the degree of pulmonary congestion and predict adverse events in heart failure outpatients
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Weber, Cristina K.

; Miglioranza, Marcelo H.

; Moraes, Maria A.P. de

; Sant'anna, Roberto T.

; Rover, Marciane M.

; Kalil, Renato A.K.

; Leiria, Tiago Luiz L.

Clinics

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2014, Volume 69 N. 5 Pages 341 - 346

Abstract: En | Text: En | PDF: En

OBJECTIVES: Proper assessment of dyspnea is important in patients with heart failure. Our aim was to evaluate the use of the 5-point Likert scale for dyspnea to assess the degree of pulmonary congestion and to determine the prognostic value of this scale for predicting adverse events in heart failure outpatients. METHODS: We undertook a prospective study of outpatients with moderate to severe heart failure. The 5-point Likert scale was applied during regular outpatient visits, along with clinical assessments. Lung ultrasound with ≥15 B-lines and an amino-terminal portion of pro-B-type natriuretic peptide (NT-proBNP) level >1000 pg/mL were used as a reference for pulmonary congestion. The patients were then assessed every 30 days during follow-up to identify adverse clinical outcomes. RESULTS: We included 58 patients (65.5% male, age 43.5±11 years) with a mean left ventricular ejection fraction of 27±6%. In total, 29.3% of these patients had heart failure with ischemic etiology. Additionally, pulmonary congestion, as diagnosed by lung ultrasound, was present in 58% of patients. A higher degree of dyspnea (3 or 4 points on the 5-point Likert scale) was significantly correlated with a higher number of B-lines (p = 0.016). Patients stratified into Likert = 3-4 were at increased risk of admission compared with those in class 1-2 after adjusting for age, left ventricular ejection fraction, New York Heart Association functional class and levels of NT-proBNP >1000 pg/mL (HR = 4.9, 95% CI 1.33-18.64, p = 0.017). CONCLUSION: In our series, higher baseline scores on the 5-point Likert scale were related to pulmonary congestion and were independently associated with adverse events during follow-up. This simple clinical tool can help to identify patients who are more likely to decompensate and whose treatment should be intensified.

https://doi.org/10.6061/clinics/2014(05)08 2926 downloads

12.

Early Mesoproterozoic (>1.4 Ga) ages from granulite basement inliers of SE Mexico and their implications on the Oaxaquia concept - Evidence from U-Pb and Lu-Hf isotopes on zircon
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Weber, Bodo

; Schulze, Carlos H.

Revista mexicana de ciencias geológicas

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2014, Volume 31 N. 3 Pages 377 - 394

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Four isolated lower crustal complexes also referred to as "Oaxaquia" are exposed in E and SE Mexico. U-Pb zircon dating by laser ablation MC-ICPMS and single-grain Lu-Hf analysis by solution MC-ICPMS were applied to zircon from ortho- and paragneiss samples. Two orthogneiss samples from the Huiznopala Gneiss yield igneous protolith ages of 1411 ± 27 Ma and 1412 ± 59 Ma, respectively. A similar age of 1444 ± 16 Ma was obtained from the "El Catrín" migmatite of the Oaxacan Complex. Hafnium isotope compositions indicate that zircon crystallized from a depleted mantle source with varying amounts of recycled crustal material. The early Mesoproterozoic crust was partially remelted during ~1.25 to 1.2 Ga arc magmatism. Paragneisses contain mainly detrital zircon sourced from these ~1.25 to 1.2 Ga igneous rocks, indicating the basin received detritus from the arc. None of the Huiznopala and Oaxacan Complex paragneiss samples contained any early Mesoproterozoic or older zircon, which implies an absence of the older protolith material during sedimentation. However, differences in Hf-isotope compositions of some detrital zircons indicate provenances from both typical Oaxaquia (juvenile Mesoproterozoic crust) and more evolved crustal precursors of the same age. Paragneiss from the Guichicovi Complex, instead, contains both early Mesoproterozoic and Paleoproterozoic zircon indicating cratonic sources. The results are interpreted in terms of a "proto-Oaxaquia" oceanic arc system that was active over early Mesoproterozoic times (1.5-1.4 Ga) during the breakup of the Columbia supercontinent. These data further suggest that this arc system was accreted to Amazonia contemporaneously with the ~1.25 to 1.2 Ga granitic arc magmatism reported in Oaxaquia and the Eastern Cordillera of Colombia. Stacking of these arc rocks along the continental margin may have caused additional migmatization around 1.1 Ga.

En el E y SE de México se encuentran expuestos cuatro complejos de corteza inferior que definen "Oaxaquia". Se realizó el fechamiento por U-Pb en zircón por ablación láser con MC-ICPMS y análisis de isótopos de Lu-Hf en granos individuales de zircón en solución por MC-ICPMS en muestras de orto- y paragneis. Dos muestras de ortogneis del Huiznopala arrojaron edades de un protolito ígneo en 1411 ± 27 Ma y 1412 ± 59 Ma, respectivamente. Una edad similar de 1444 ± 16 Ma se obtuvo de la migmatita "El Catrín" del complejo Oaxaqueño. Las composiciones isotópicas de Hf indican que el zircón cristalizó de una fuente en el manto empobrecido con cantidades variadas de corteza reciclada. La corteza del Mesoproterozoico temprano se fundió parcialmente durante un magmatismo de arco entre 1.25 y 1.2 Ga. El paragneis contiene esencialmente zircón detrítico proveniente de estas rocas ígneas con edades de entre 1.25 y 1.2 Ga, indicando que el detritus proviene substancialmente de las rocas de arco. Ninguna de las muestras de paragneis del complejo Oaxaqueño y Huiznopala contiene zircón del Mesoproterozoico temprano o más antiguo, lo que implica ausencia de protolitos más antiguos durante la sedimentación. Sin embargo, las diferencias en la composición isotópica de algunos zircones detríticos indican proveniencias de dos fuentes, uno de Oaxaquia típico (corteza mesoproterozoica juvenil) y un precursor cortical más evolucionado de la misma edad. El paragneis del complejo Guichicovi, en cambio, también contiene zircones del Mesoproterozoico temprano y del Paleoproterozoico, lo que indica fuentes cratónicas. Los resultados se interpretan en términos de un sistema de arco oceánico llamado "proto-Oaxaquia", que estuvo activo en el Mesoproterozoico temprano (1.5-1.4 Ga) durante la desintegración del supercontinente Columbia. Adicionalmente, los datos sugieren que este sistema de arco fue acrecionado a Amazonia contemporáneamente al magmatismo de arco entre 1.25 a 1.2 Ga, reportado en Oaxaquia y en la Cordillera del Este de Colombia. El apilamiento de estas rocas de arco a lo largo del margen continental pudo haber causado una migmatización de alrededor de 1.1 Ga.

2611 downloads

13.

Survey of pharmacist-managed primary care clinics using healthcare failure mode and effect analysis
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Vincent, Ashley H.

; Gonzalvo, Jasmine D.

; Ramsey, Darin C.

; Walton, Alison M.

; Weber, Zachary A.

; Wilhoite, Jessica E.

Pharmacy Practice (Granada)

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2013, Volume 11 N. 4 Pages 196 - 202

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objectives: The primary objective was to expand upon results of a previously piloted patient perception survey with Healthcare Failure Mode and Effect Analysis (HFMEA), to identify areas within pharmacist-managed clinics needing improvement. Methods: The survey was adapted for use in pharmacist-managed clinics. Patients completed the survey following regularly scheduled pharmacist appointments. Data were analyzed with a method adapted from HFMEA. Product scores could range from five to 25. A product of five indicates that pharmacists are doing a good job on the items that patients place the most value on, while a product score of 25 indicates that pharmacists are doing a poor job. A score greater than or equal to ten was used to identify areas for improvement. Results: Seventy-one patients completed surveys. Thirteen components were assessed and no item achieved a mean product greater than or equal to ten. The survey item with the highest mean product pertained to discussion of potential medication side effects (mean: 7.06; interquartile range: 5-10). Analysis of each survey item found that all survey items had multiple individual responses that provided a product score of greater than or equal to ten. The survey items most frequently listed in the overall population as being most valued were "Told you the name of each of your medicines and what they are used for", "Answered your questions fully," and "Explained what your medicines do". Conclusions: Educational components provided during pharmacist-managed clinic appointments are aligned with patients´ needs and are successfully incorporating the components that patients value highly in a patient-healthcare provider interaction. The HFMEA model can be an important teaching tool to identify specific processes in need of improvement and to help enhance pharmacists´ self-efficacy, which may further improve patient care.

Objetivos: El objetivo primario fue profundizar sobre los resultados de un cuestionario pre-pilotado de percepciones de los pacientes con el análisis de modos y efectos de fallos en salud (HFMEA) para identificar áreas en las que las consultas de farmacéuticas necesitan mejorar. Métodos: El cuestionario fue adaptado para su uso en consultas farmacéuticas. Los pacientes cubrieron el cuestionario después de las citas farmacéuticas acordadas. Los datos se analizaron usando un método adaptado del HFMEA. Las puntuaciones de producto podían oscilar de 5 a 25. Un producto de 5 indicaba que el farmacéutico estaba realizando un buen trabajo en los ítems que el paciente valorizaba más, mientras que una puntuación de 25 indicaba que el farmacéutico estaba haciendo un mal trabajo. Se utilizaron las puntuaciones de 10 o más para identificar áreas de mejoría. Resultados: 71 pacientes completaron cuestionarios. Se evaluaron 33 componentes y ningún ítem alcanzó un producto medio mayor o igual a 10. El punto de la encuesta que alcanzó la media más alta trataba de la discusión de los potenciales efectos secundarios de la medicación (media: 7.06; rango intercuartilico: 5-10). El análisis de cada ítem del cuestionario encontró que todos los ítems tenían varias respuestas individuales que proporcionaban una puntuación igual o mayor de 10. Los ítems más frecuentemente considerados por la población total como siendo los más valorados fueron "le dijo el nombre de todos sus medicamentos y para que se usan", "respondió completamente sus preguntas" y "explico lo que hacen los medicamentos". Conclusiones: Los componentes educativos proporcionados en las visitas a las consultas farmacéuticas se alinean con las necesidades de los pacientes e incorporan con éxito los componentes que los pacientes valoran más en la interacción paciente-profesional de la salud. El modelo HFMEA puede ser una importante herramienta educativa para identificar procesos específicos que necesitan mejorar y para ayudar a aumentar la auto-eficacia de los farmacéuticos, lo que podrá en el futuro mejorar la atención a pacientes.

341 downloads

14.

Diversity of 16S rRNA genes from bacteria of sugarcane rhizosphere soil
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Pisa, G.

; Magnani, G.S.

; Weber, H.

; Souza, E.M.

; Faoro, H.

; Monteiro, R.A.

; Daros, E.

; Baura, V.

; Bespalhok, J.P.

; Pedrosa, F.O.

; Cruz, L.M.

Brazilian Journal of Medical and Biological Research

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2011, Volume 44 N. 12 Pages 1215 - 1221

Abstract: En | Text: En | PDF: En

Sugarcane is an important agricultural product of Brazil, with a total production of more than 500 million tons. Knowledge of the bacterial community associated with agricultural crops and the soil status is a decisive step towards understanding how microorganisms influence crop productivity. However, most studies aim to isolate endophytic or rhizosphere bacteria associated with the plant by culture-dependent approaches. Culture-independent approaches allow a more comprehensive view of entire bacterial communities in the environment. In the present study, we have used this approach to assess the bacterial community in the rhizosphere soil of sugarcane at different times and under different nitrogen fertilization conditions. At the high taxonomic level, few differences between samples were observed, with the phylum Proteobacteria (29.6%) predominating, followed by Acidobacteria (23.4%), Bacteroidetes (12.1%), Firmicutes (10.2%), and Actinobacteria (5.6%). The exception was the Verrucomicrobia phylum whose prevalence in N-fertilized soils was approximately 0.7% and increased to 5.2% in the non-fertilized soil, suggesting that this group may be an indicator of nitrogen availability in soils. However, at low taxonomic levels a higher diversity was found associated with plants receiving nitrogen fertilizer. Bacillus was the most predominant genus, accounting for 19.7% of all genera observed. Classically reported nitrogen-fixing and/or plant growth-promoting bacterial genera, such as Azospirillum, Rhizobium, Mesorhizobium, Bradyrhizobium, and Burkholderia were also found although at a lower prevalence.

5634 downloads Cited 3 times in SciELO

15.

A new dark-saddled species of Hypostomus (Siluriformes: Loricariidae) from the upper rio Paraguay basin
Facebook Twitter

Other social networks
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Other networks

Metrics
- SciELO Analytics

Zawadzki, Cláudio Henrique

; Weber, Claude

; Pavanelli, Carla Simone

Neotropical Ichthyology

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2010, Volume 8 N. 4 Pages 719 - 725

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Uma espécie nova de Hypostomus é descrita do rio Cuiabá, bacia do alto rio Paraguai, Estado do Mato Grosso, Brasil. A espécie nova é diagnosticada de todas as outras congêneres, com exceção de H. latifrons, pela presença de amplas barras escuras transversais nas laterais do corpo e nadadeiras, e pelas conspícuas vermiculações escuras na região abdominal. De H. latifrons ela difere por ter somente uma placa pré-dorsal margeando o osso supraoccipital e pela manutenção das barras escuras transversais nos adultos. Somada a outras espécies de peixes recentemente descritas na bacia do alto rio Paraguai, este trabalho demonstra que a região ainda funciona como uma fonte potencial de espécies novas.

A new Hypostomus species is described from the rio Cuiabá, upper rio Paraguay basin, Mato Grosso State, Brazil. The new species is distinguished from all other Hypostomus species, with exception of young specimens of H. latifrons, by the presence of a wide dark transverse bars on laterals of body and fins; and conspicuous dark vermiculations on abdominal region. From H. latifrons it differs by having just one pre-dorsal plate surrounding supraoccipital bone and by the maintenance of the dark saddles in adults. Added to the other fish species recently described from the upper rio Paraguay basin, this work helps to highlight that the region still functions as a potential source of new species.

3256 downloads Cited 7 times in SciELO

Showing

itens per page

Page of 2 Next

Select one or more results

All Alphabetic

Results

Comparative chart Download CSV

Statistics of

Send result

To*

Use ; (semicolon) to insert more emails.

Send to email

This page

Selected records

All references (max. 300)

Your email

Subject

Comments

Export format:

RIS (for EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citation

CSV (for Excel, etc)

Export:

This page

Selected itens

All references (max. 2000)

Sem resultados

No documents were found for your search

Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

All the contents of this site www.scielo.br, except where otherwise noted, is licensed under a Creative Commons Attribution License.
more »