Resumo Exceto por alguns insetos-pau que são economicamente valiosos, a maioria das espécies pode ser considerada praga florestal, por isso é extremamente importante obter informações sobre o uso de hospedeiros de plantas de mais insetos-pau. Neste artigo, as plantas hospedeiras de três espécies de bicho-pau foram registradas pela primeira vez. Também descobrimos que esses bichos-pau podem se alimentar de flores ou folhas de plantas. Lopaphus unidentatus (Chen & He, 1995) (Phasmida: Lonchodidae) atacou a parede de Hypericum choisianum. ex N. Robson, 1973 (Hypericaceae), Leurophasma dolichocercum Bi, 1995 (Phasmida: Aschiphasmatidae) atacou Antenoron filiforme (Thunb.) Roberty & Vautier, 1964 (Polygonaceae) e Megalophasma granulatum Bi, 1995 (Phasmida: Lonchodidae orientaled) atacou Chen, 1991 (Urticaceae). Finalmente, tivemos a sorte de também obter fotos deles se acasalando e se alimentando.

Abstract Except for a few stick insects that are economically valuable, most species be considered to be forest pests, so it is extremely important to obtain plant host-use information of more stick insects. In this paper, the plant hosts of three species of stick insects were recorded for the first time. We also discovered these stick insects can feed upon the flowers or leaves of plants. Lopaphus unidentatus (Chen & He, 1995) (Phasmida: Lonchodidae) attacked Hypericum choisianum Wall. ex N. Robson, 1973 (Hypericaceae), Leurophasma dolichocercum Bi, 1995 (Phasmida: Aschiphasmatidae) attacked Antenoron filiforme (Thunb.) Roberty & Vautier, 1964 (Polygonaceae) and Megalophasma granulatum Bi, 1995 (Phasmida: Lonchodidae) attacked Debregeasia orientalis C. J. Chen, 1991 (Urticaceae). Finally, we were lucky enough to also obtain photographs of them mating and feeding.

Resumo A baixa estatura é um problema significativo de saúde pública em países de baixa e média renda. Este estudo avaliou a prevalência de nanismo e os fatores de risco associados de nanismo entre crianças em idade pré-escolar e em idade escolar em áreas afetadas por inundações do Paquistão. Foi realizado um estudo transversal visitando 656 domicílios por meio de amostragem em múltiplos estágios. As medidas antropométricas do entrevistado, informações sociodemográficas e instalações de saneamento foram exploradas. Um modelo de regressão logística foi usado para determinar os determinantes do nanismo, controlando todos os possíveis fatores de confusão. A prevalência geral de baixa estatura em crianças foi de 40,5%, entre as crianças 36,1% dos meninos e 46,3% das meninas com baixa estatura. A prevalência de baixa estatura em crianças menores de 5 anos foi de 50,7%. Crianças do sexo feminino (OR = 1,35, IC de 95%: 0,94-2,0), crianças de 13-24 meses (OR = 6,5, IC de 95%: 3,0-13,9), mães de 15-24 anos (OR = 4,4, IC de 95%: 2,6-7,2), família conjunta (OR = 2,1, IC 95%: 1,4-3,0) não tiveram acesso a água potável de qualidade (OR = 3,3, IC 95%: 1,9-5,9) e a banheiro (OR = 2,8, IC de 95%, 1,9-4,3), enquanto as crianças do distrito de Nowshera (OR = 1,7, IC de 95%: 0,9-3,2) foram significativamente (P < 0,05) associadas na análise univariada. O modelo de regressão revelou que a idade da criança, idade materna, tipo de família, qualidade da água e banheiro foram os fatores significativos (P < 0,05) que contribuíram para a baixa estatura infantil nas áreas afetadas pelas enchentes. A identificação de fatores-chave pode ser útil para os formuladores de políticas no planejamento de programas comunitários abrangentes para a redução da baixa estatura em áreas afetadas pelas enchentes. Em desastres como enchentes, as consequências prejudiciais do problema de baixa estatura podem ser ainda maiores para as crianças. Educação baseada em evidências e cuidados deve ser fornecida às famílias nas regiões afetadas pelas enchentes para reduzir o problema de nanismo. Os determinantes do retardo de crescimento devem ser almejados pela formulação de políticas abrangentes sobre nutrição adequada, meios de subsistência, água potável e instalações de saneamento nas regiões afetadas pelas enchentes.

Abstract Stunting is a significant public health problem in low- and middle-income countries. This study assessed the prevalence of stunting and associated risk factors of stunting among preschool and school-going children in flood-affected areas of Pakistan. A cross-sectional study was conducted by visiting 656 households through multi-stage sampling. Respondent’s anthropometric measurements, socio-demographic information and sanitation facilities were explored. A logistic regression model was used to determine determinants of stunting, controlling for all possible confounders. The overall prevalence of stunting in children was 40.5%, among children 36.1% boys and 46.3% of girls were stunted. The prevalence of stunting in under-five children was 50.7%. Female children (OR=1.35, 95% CI:0.94-2.0), children aged 13-24 months (OR=6.5, 95% CI: 3.0-13.9), mothers aged 15-24 years (OR=4.4, 95% CI: 2.6-7.2), joint family (OR=2.1, 95% CI: 1.4-3.0) did not have access to improved drinking water (OR=3.3, 95% CI: 1.9-5.9), and the toilet facility (OR=2.8, 95% CI, 1.9-4.3), while the children from district Nowshera (OR=1.7, 95% CI: 0.9-3.2) were significantly (P<0.05) associated in univariate analysis. The regression model revealed that child age, maternal age, family type, quality of water, and toilet facility, were the significant (P<0.05) factors contributing to child stunting in the flood-hit areas. Identification of key factors might be helpful for policymakers in designing comprehensive community-based programs for the reduction of stunting in flood-affected areas. In disasters such as flood, the detrimental consequences of the stunting problem could be even more on children. Evidence-based education and care must be provided to the families in the flood-affected regions to reduce the stunting problem. The determinants of stunting should be targeted by making comprehensive policies regarding proper nutrition, livelihood, clean water, and sanitation facilities in flood-hit regions.

ABSTRACT In order to provide the basis for the design and control of a citrus picking robot clamp and cutter, and find the optimal combination of cutting parameters, this study used a self-made citrus stem cutting test-bed to study the effects of the citrus stem diameter, blade cutting speed, blade cutting clearance, and tool sliding cutting angle on the peak cutting force of citrus stems through a single-factor experiment. Based on the single-factor test, the blade cutting speed, blade cutting clearance, and tool sliding angle are selected as the influencing factors, and a multi-factor test is carried out with the target of the peak cutting force, and the regression model is established. The results showed that the peak cutting force increased linearly with the diameter of the fruit stalk, decreased with the increase of the blade cutting speed and sliding cutting angle, and first decreased and then increased with the increase of the blade cutting clearance. Through the optimisation analysis of the regression model, it is found that the optimal cutting parameter combination is the blade cutting speed of 40 mm/min, blade cutting gap of 1 mm, tool sliding cutting angle of 20°, and the peak cutting force under this combination is 168.23 N. The deviation between the predicted value of the peak cutting force and the measured value is less than 2%, and the optimisation result of the cutting parameters is reliable. This study provides a theoretical basis for the optimal design and control of the clamping and cutting mechanism of the citrus picking robot.

We propose a technique that enhances the bandwidth efficiency of the two transmit antenna differential space-time block code (DSTBC) by use of space-time block code (STBC) expansion and trellis coding. STBC expansion is realized by expanding the conventional Alamouti STBC using unitary matrix transformation. This is followed by trellis code-aided mapping of additional bits to space-time codes of the expanded set. Trellis code-aided mapping of additional bits enhances the bandwidth efficiency of the proposed DSTBC scheme. The proposed scheme sends more information bits in each transmitted space-time code than the conventional differential detection-aided DSTBC (CDD-DSTBC) scheme, and yet retains the same error performance. For each additional bit sent with the transmitted space-time codeword, the proposed scheme using 16QAM achieves a 12.5% increase in bandwidth efficiency, while the scheme using 64QAM realises an 8.3% increase. Simulation results demonstrate that the error performance of the proposed scheme tightly matches that of CDD-DSTBC with improvement in bandwidth efficiency. The bandwidth efficiency is enhanced at the expense of a moderate increase of the computational complexity at the receiver.

Multiple-input multiple-output (MIMO) systems have attracted a vast amount of interest, due to improvements offered in capacity and diversity. However, several challenges still remain. Single transmit antenna selection with modulation (STASM) is an important closed-loop variant of MIMO, and addresses several of its challenges, while achieving full-diversity. On this note, the average symbol error probability (ASEP) of STASM with M-ary quadrature amplitude modulation (M-QAM) and M-ary phase shift keying (M-PSK) is formulated and validates the Monte Carlo simulation results. The formulated ASEP expressions are relatively easy to evaluate. Euclidean distance-based antenna selection for spatial modulation (EDAS-SM) is an innovative closed-loop MIMO scheme that provides many advantages. However, since STASM achieves a full-diversity compared to EDAS-SM, there exists a cross-over point after which its error performance is superior to the latter. For multiple receive antennas, the cross-over point only occurs in the moderate-to-high signal-to-noise ratio region, which may be difficult to achieve in practice. Hence, an adaptive transmit mode switching system based on STASM and EDAS-SM as transmission candidates is proposed. A selection criterion for the transmission candidate is based on minimizing the instantaneous symbol error probability in every transmission interval. By switching between STASM and EDAS-SM, the proposed scheme minimizes the ASEP.

In this study, the authors propose two low-complexity near-maximum-likelihood (ML) detection algorithms for spatial modulation (SM) systems, employing the new multiple-ring star-M-ary quadrature amplitude modulation (MR-STAR-MQAM) constellation. The proposed detectors exploit the specific orientation of MR-STAR-MQAM, in order to avoid searching across all constellation points. As a result, the computational complexity is independent of both the constellation size and the number of rings presented in MR-STAR-MQAM. In addition, these detectors are generalized and can be applied to the entire star-MQAM family. The Monte Carlo simulation results demonstrate that the proposed detection algorithms achieve the same average bit error rate (ABER) as ML detection for SM but at a much lower computational complexity. For example, in a 4x4, 2R-STAR-16QAM aided SM system, the proposed optimal and sub-optimal detectors achieve an 88.8% and 90.5% reduction in computational complexity, respectively, compared to the ML detector. Furthermore, the simulation results are supported by a closed-form union-bound theoretical ABER expression.

Space shift keying (SSK) modulation is a special case of conventional spatial modulation (SM), where the amplitude and/or phase modulation symbols are eliminated from the transmission process so as to reduce complexity. However, high spectral efficiencies are difficult to achieve with SSK. At the same time, the spectral efficiency of SM can be further improved. On this note, to further enhance the spectral efficiencies of both SM and SSK, quadrature SM (QSM) and Bi-SSK modulations, respectively, were proposed. In coded channels, typically soft-output detection coupled with soft-input channel decoding yields significant signal-to-noise ratio (SNR) gain. Hence, in this paper, we propose soft-output maximum-likelihood detectors (SOMLD) for SSK, Bi-SSK and QSM modulated systems. Monte Carlo simulation results demonstrate that the error performances of the proposed SOMLD schemes closely match with that of their hard-decision maximum-likelihood detector counterparts in uncoded channels; while, significant SNR gains are yielded in coded channels.

A special case of conventional spatial modulation (SM) is demonstrated in space shift keying (SSK) modulation, where the amplitude and/or phase modulation symbols are eliminated from the transmission process so as to reduce system complexity. However, the spectral efficiencies of both schemes increase only logarithmically. Hence, large antenna arrays are required to achieve high spectral efficiencies. To reduce the transceiver overhead, while achieving improved spectral efficiencies in both SM and SSK, generalised SM (GSM) and generalised SSK (GSSK), respectively, were proposed. Typically, in coded channels, soft-output detection coupled with soft-input channel decoding yields significant signal-to-noise ratio (SNR) gain. Hence, in this paper, we propose soft-output maximum-likelihood (ML) detectors (SOMLDs) for the GSM and GSSK schemes, with an aim to further improve the error performance of the systems. Monte Carlo simulation results demonstrate that the error performance of the proposed SOMLD schemes closely match with that of their hard-decision ML detector counterparts in uncoded channels; while significant SNR gains are yielded in coded channels.

The aim of this study was to investigate the mechanism of propranolol on the regression of hemangiomas. Propranolol-treated hemangioma tissues were collected and the expression of hypoxia inducible factor-1α (HIF-1α) was examined. We also established HIF-1α overexpression and knockdown hemangioma cells, and determined the effects of HIF-1α on the hemangioma cells proliferation, apoptosis, migration and tube formation. Significantly increased HIF-1α level was found in the hemangioma tissues compared to that in normal vascular tissues, whereas propranolol treatment decreased the HIF-1α level in hemangioma tissues in a time- and dose-dependent manner. Moreover, propranolol treatment significantly decreased cell proliferation, migration and tube formation as well as promoted cell apoptosis in HIF-1α overexpression and knockdown hemangioma cells. Propranolol suppressed the cells proliferation, migration and tube formation of hemangioma cells through HIF-1α dependent mechanisms. HIF-1α could serve as a novel target in the treatment of hemangiomas.

Background Cysteine proteinase inhibitor (cystatin, CPI) is one of the most important molecules involved in plant development and defense, especially in the regulation of stress responses. However, it is still unclear whether the Jatropha curcas CPI (JcCPI) gene functions in salinity response and tolerance. In this study, the sequence of the JcCPI gene, its expression pattern, and the effects of overexpression in Escherichia coli and Nicotiana benthamiana were examined. The purpose of this study was to evaluate the regulatory role of JcCPI in salinity stress tolerance. Results The CPI gene, designated JcCPI, was cloned from J. curcas; its sequence shared conserved domains with other plant cystatins. Based on a transcription pattern analysis, JcCPI was expressed in all tissues examined, but its expression was highest in the petiole. Additionally, the expression of JcCPI was induced by salinity stress. A potential role of JcCPI was detected in transgenic E. coli, which exhibited strong CPI activity and high salinity tolerance. JcCPI was also transferred to tobacco plants. In comparison to wild-type plants, transgenic plants expressing JcCPI exhibited increased salinity resistance, better growth performance, lower malondialdehyde (MDA) contents, higher anti-oxidase activity, and higher cell viability under salinity stress. Conclusions Based on the results of this study, overexpression of JcCPI in E. coli and N. benthamiana conferred salinity stress tolerance by blocking cysteine proteinase activity. The JcCPI gene cloned in this study will be very useful for the development of stress-tolerant crops.

In this study, biomarkers and transcriptional factor motifs were identified in order to investigate the etiology and phenotypic severity of Down syndrome. GSE 1281, GSE 1611, and GSE 5390 were downloaded from the gene expression ominibus (GEO). A robust multiarray analysis (RMA) algorithm was applied to detect differentially expressed genes (DEGs). In order to screen for biological pathways and to interrogate the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway database, the database for annotation, visualization, and integrated discovery (DAVID) was used to carry out a gene ontology (GO) function enrichment for DEGs. Finally, a transcriptional regulatory network was constructed, and a hypergeometric distribution test was applied to select for significantly enriched transcriptional factor motifs. CBR1, DYRK1A, HMGN1, ITSN1, RCAN1, SON, TMEM50B, and TTC3 were each up-regulated two-fold in Down syndrome samples compared to normal samples; of these, SON and TTC3 were newly reported. CBR1, DYRK1A, HMGN1, ITSN1, RCAN1, SON, TMEM50B, and TTC3 were located on human chromosome 21 (mouse chromosome 16). The DEGs were significantly enriched in macromolecular complex subunit organization and focal adhesion pathways. Eleven significantly enriched transcription factor motifs (PAX5, EGR1, XBP1, SREBP1, OLF1, MZF1, NFY, NFKAPPAB, MYCMAX, NFE2, and RP58) were identified. The DEGs and transcription factor motifs identified in our study provide biomarkers for the understanding of Down syndrome pathogenesis and progression.

Hepatic progenitor cells (HPCs) are a potential cell source for liver cell transplantation but do not function like mature liver cells. We sought an effective and reliable method to induce HPC maturation. An immortalized HP14.5 albumin promoter-driven Gaussian luciferase (ALB-GLuc) cell line was established from HPCs isolated from fetal mouse liver of post coitus day 14.5 mice to investigate the effect of induction factors on ALB promoter. HP14.5 parental cells were cultured in DMEM with different combinations of 2% horse serum (HS), 0.1 µM dexamethasone (DEX), 10 ng/mL hepatic growth factor (HGF), and/or 20 ng/mL fibroblast growth factor 4 (FGF4). Trypan blue and crystal violet staining were used to assess cell proliferation with different induction conditions. Expression of hepatic markers was measured by semi-quantitative RT-PCR, Western blot, and immunofluorescence. Glycogen storage and metabolism were detected by periodic acid-Schiff and indocyanine green (ICG) staining. GLuc activity indicated ALB expression. The combination of 2% HS+0.1 µM Dex+10 ng/mL HGF+20 ng/mL FGF4 induced the highest ALB-GLuc activity. Cell proliferation decreased in 2% HS but increased by adding FGF4. Upon induction, and consistent with hepatocyte development, DLK, AFP, and CK19 expression decreased, while ALB, CK18, and UGT1A expression increased. The maturity markers tyrosine aminotransferase and apolipoprotein B were detected at days 3 and 6 post-induction, respectively. ICG uptake and glycogen synthesis were detectable at day 6 and increased over time. Therefore, we demonstrated that HPCs were induced to differentiate into functional mature hepatocytes in vitro, suggesting that factor-treated HPCs may be further explored as a means of liver cell transplantation.

Recent results on chemical freeze-out, elliptic flow v2 and multi-strange hadron transverse momentum distributions are discussed and compared with model predictions. The idea of heavy flavor collectivity and light flavor thermalization is presented in the light of recent heavy flavor measurement at RHIC.