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au:AIDAR, FELIPE JOSE

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Effect of 15 consecutive HIIT sessions on the redox State in Wistar rats
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Rodrigues, Josimar Camacho

; Costa, Roas de Araújo

; Aidar, Felipe José

; Souza, Raphael Fabrício de

; Brito, Ciro José

; Santos, Jymmys Lopes dos

; Vieira-Souza, Lucio Marques

Motricidade

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Set 2023, Volume 19 Nº 3 Páginas 306 - 312

Resumo: En | Texto: En | PDF: En

ABSTRACT High-intensity interval training (HIIT) can induce oxidative stress. The main aim of this study was to evaluate the effect of 15 sessions of a HIIT protocol in Wistar rats on oxidative damage markers in different tissues (blood, muscle, liver and heart). Thus, animals weighing 250-300 g were used and randomly divided into 2 groups (n= 10): Control (CG) and animals submitted to HIIT (TG) through a swimming protocol. The results showed that HIIT increased the production of malondialdehyde (MDA) in TG animals: serum (306.75%), gastrocnemius muscle (259.2%), liver (452.6%) and heart (215%), while the concentration of sulfhydryl groups decreased: serum (40%), gastrocnemius muscle (44.7%), liver (44.6%) and heart (47.2%). Thus, it could be concluded that 15 HIIT sessions altered the redox state of Wistar rats due to increased oxidative damage markers in the analysed tissues.

https://doi.org/10.6063/motricidade.31537

HIGH-INTENSITY INTERVAL TRAINING POSES NO RISK TO HYPERTENSIVE WOMEN
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Vieira-Souza, Lucio Marques

; Aidar, Felipe José

; Mota, Márcio Getirana

; Reis, Gracielle Costa

; Lima Júnior, Cássio Murilo Almeida

; Silva, Fábio José Antônio da

; Jesus, Joseane Barbosa de

; Azevedo, David Edson Ramos de

; Marçal, Anderson Carlos

; Santos, Jymmys Lopes dos

Revista Brasileira de Medicina do Esporte

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2023, Volume 29 elocation e2021_0321

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Introdução: O objetivo deste estudo foi avaliar se uma única sessão de treinamento intervalado de alta intensidade (HIIT) promoveria efeito hipotensor e risco cardiovascular em mulheres hipertensas, bem como aumentar a biodisponibilidade de óxido nítrico. Métodos: A amostra foi composta por 10 mulheres hipertensas (63,7 ± 10,34 anos; 66, ± 7,67 kg e 153,7 ± 9,08 cm) e a carga de treinamento foi estabelecida em 60% da velocidade aeróbica máxima. Resultados: Observamos um efeito hipotensor muito alto entre os momentos de interação durante a intervenção (Int. Pré: 122,40 ± 18,58; Int. Pós: 143,00 ± 24,90; Int. Pós 60 min.: 121,40 ± 13,87; p < 0,001, η2P = 0,569). Nenhum risco cardiovascular foi observado durante a intervenção (DP = Int. Pré: 9138,20 ± 1805,34; Int. Pós: 14849,70 ± 3387,94; Int. Pós: 60 min.: 9615,90 ± 1124,41, p < 0,001, η2P = 0,739) e não houve aumento da biodisponibilidade de óxido nítrico. Conclusões: Em conclusão, este trabalho revela que uma sessão de HIIT é capaz de gerar efeito hipotensor sem apresentar risco cardiovascular em mulheres hipertensas. Nível de evidência I; Estudo clínico randomizado de alta qualidade com ou sem diferença estatisticamente significativa, mas com intervalos de confiança estreitos .

ABSTRACT Introduction: The aim of this study was to evaluate whether a single session of high-intensity interval training (HIIT) would promote a hypotensive effect and cardiovascular risk in hypertensive women, in addition to increasing the bioavailability of nitric oxide. Methods: The sample consisted of 10 hypertensive women (63.7 ± 10.34 years; 66 ± 7.67 kg and 153.7 ± 9.08 cm) and the training load was established at 60% of the maximum aerobic speed. Results: We observed a very high hypotensive effect between the interaction moments during the intervention (Int. Pre: 122.40 ± 18.58; Int. Post: 143.00 ± 24.90; Int. Post 60min: 121.40 ± 13.87; p<0.001, η2P = 0.569). No cardiovascular risk was observed during the intervention (DP = Int. Pre: 9138.20 ± 1805.34; Int. Post: 14849.70 ± 3387.94; Int. Post 60min: 9615.90 ± 1124.41, p< 0.001, η2P = 0.739) and there was no increase in the bioavailability of nitric oxide. Conclusion: In conclusion, this work reveals that an HIIT session is capable of generating a hypotensive effect while not posing cardiovascular risk in hypertensive women. Level of evidence I; High-quality randomized clinical trial with or without statistically significant difference, but with narrow confidence intervals .

RESUMEN Introducción: El objetivo de este estudio fue evaluar si una única sesión de entrenamiento de intervalos de alta intensidad (HIIT) podría promover un efecto hipotensor y riesgo cardiovascular en mujeres hipertensas, así como aumentar la biodisponibilidad del óxido nítrico. Métodos: La muestra fue compuesta por 10 mujeres hipertensas (63,7 ± 10,34 años; 66 ± 7,67 kg y 153,7 ± 9,08 cm) y la carga de entrenamiento se estableció en el 60% de la velocidad aeróbica máxima. Resultados: Se observó un efecto hipotensor muy elevado entre los momentos de interacción durante la intervención (Int. Pre: 122,40 ± 18,58; Int. Post: 143,00 ± 24,90; Int. Post 60 min: 121,40 ± 13,87; p <0,001, η2P = 0,569). No se observó ningún riesgo cardiovascular durante la intervención (DP = Int. Pre: 9138,20 ± 1805,34; Int. Post: 14849,70 ± 3387,94; Int. Post 60 min: 9615,90 ± 1124,41, p <0,001, η2P = 0,739) y no hubo aumento de la biodisponibilidad de óxido nítrico. Conclusiones: En conclusión, este trabajo revela que una sesión de HIIT es capaz de generar efecto hipotensor sin presentar riesgo cardiovascular en mujeres hipertensas. Nivel de evidencia I; Estudio clínico aleatorizado de alta calidad con o sin diferencia estadísticamente significativa, pero con intervalos de confianza estrechos.

https://doi.org/10.1590/1517-8692202329012021_0321

Non-Targeted Self-Measured Blood Pressure and Hypertension Control in Public and Private Health Systems in Brazil
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Salazar, Gabriela de Oliveira

; Almeida, Glessiane de Oliveira

; Barreto-Filho, José Augusto Soares

; Almeida-Santos, Marcos Antônio

; Melo, Enaldo Vieira de

; Aidar, Felipe J.

; Cruz, José Ícaro Nunes

; Oliveira, Joselina Luzia Menezes

; Baumworcel, Leonardo

; Sousa, Antônio Carlos Sobral

International Journal of Cardiovascular Sciences

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2023, Volume 36 elocation e20220144

Resumo: En | Texto: En | PDF: En

Abstract Background: It is estimated that more than 30% of the Brazilian population has systemic arterial hypertension (SAH), and mostly as an uncontrolled disease. The most recent Brazilian Guideline of Hypertension recommends the practice of self-measurement of blood pressure (BP) as one of the strategies for a better control of SAH, but there is no consensus about the efficiency of this tool. Objective: To assess the control of SAH and the practice of non-targeted self-measured BP (SMBP) among hypertensive users of the Unified Health System (SUS) and the Supplementary Network (SN). Methods: This is a cross-sectional, observational, analytical study, with a stratified probability sample. One thousand volunteers were investigated, being 500 from SUS and 500 from the SN. Uni and multivariate analyses were performed considering a 5% significance level. Results: Patients from SUS presented inferior sociodemographic data (schooling, social status) in relation to those of the SN (p < 0.001), and showed lower control of SAH (p = 0.014), as well as more visits to the emergency room in the past year due to hypertension (p = 0.002), and fewer regular appointments with the cardiologist (p = 0.004). SMBP was equally present in both assessed groups (p = 0.567), even though users of the SN have been more advised to not conduct such a practice (p = 0.002). SMBP (p < 0.001) was an independent factor for uncontrolled SAH both in SUS (OR = 3.424) and in the SN (OR = 3.474). Conclusion: Patients in SUS presented lower SAH control. The practice of SMBP, mostly practiced with an uncalibrated digital device, was equally present in both groups and became an independent factor of uncontrolled SAH.

https://doi.org/10.36660/ijcs.202220144

I Registro de Insuficiência Cardíaca Congestiva do Estado de Sergipe, Brasil: desenho e justificativa
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Barbosa, Juliana Santos

; Costa, Jamille Oliveira

; Alves, Luciana Vieira Sousa

; Souza, Marcia Ferreira Cândido de

; Almeida-Santos, Marcos Antonio

; Oliveira, Joselina Luzia Menezes

; Barreto Filho, José Augusto Soares

; Aidar, Felipe José

; Sousa, Antônio Carlos Sobral

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Dez 2022, Volume 18 Nº 2 Páginas 355 - 361

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The Heart Failure (HF) is responsible for a large number of hospitalizations in Brazil, but there is still a considerable gap in the scrutiny of the public health system (SUS) regarding the quality of care provided. Objective: to describe the methodology used in the VICTIM-CHF study, which aims to characterize and compare the nutritional, clinical, lifestyle, treatment received, outcomes, as well as the possible disparities observed among patients in Brazil. Methodology: This is a cross-sectional, descriptive and prospective study, carried out with patients with heart failure (HF) admitted to 4 hospitals in Sergipe, Brazil. Clinical, sociodemographic, nutritional, quality of life and outcomes (death and readmission) parameters will be investigated up to 30 days after hospital discharge. Preliminary results of ten volunteers: 70% were male, 60% adults. The most frequent etiology was ischemic (50%), 50% had HF with preserved ejection fraction (EF) and the remainder, with intermediate EF. Malnutrition, according to BMI, was present in 20% and the hospital stay was significantly (p= 0.036) longer in SUS users. Conclusion: The VICTIM-CHF Registry aims to identify opportunities for improvement in the line of care for HF users of the SUS and the supplementary health system. It is hoped that the findings of this investigation can help to optimize the strategic planning of more efficient and equitable health policies.

RESUMO A Insuficiência Cardíaca (IC) é responsável por um grande número de internações no Brasil, mas ainda existe considerável lacuna escrutinizando o sistema de saúde pública (SUS) no tocante a qualidade assistencial praticada. Objetivo: descrever a metodologia empregada no estudo VICTIM-CHF que tem como objetivo caracterizar e comparar os aspectos nutricionais, clínicos, estilo de vida, tratamento recebido, desfechos, bem como as possíveis disparidades observadas entre os pacientes Brasil, mas ainda existe considerável lacuna escrutinizando o sistema de saúde pública (SUS) no tocante a qualidade assistencial praticada. Métodologia: Trata-se de estudo transversal, descritivo e prospective, realizado com portadores de insuficiência cardíaca (IC), internados em 4 hospitais de Sergipe, Brasil. Serão investigados parâmetros clínicos, sociodemográficos, nutricionais, qualidade de vida e desfechos (morte e reinternação) até 30 dias após a alta hospitalar. Resultados preliminaries de dez voluntários: 70% eram do sexo masculine, sendo 60% adultos. A etiologia mais frequente foi a isquêmica (50%), 50% exibia IC pcom fração de ejeção (FE) preservada e o restante, com FE intermediária. Desnutrição, segundo o IMC, esteve presente em 20% e o período de internação foi, significativamente (p= 0,036) superior nos usuários do SUS. Conclusão: O Registro VICTIM-CHF visa identificar oportunidades de melhoria na linha de cuidado para a IC de usuários do SUS e do Sistema de saúde suplementar. Espera-se que os achados desta investigação possam ajudar a otimizar o planejamento estratégico de políticas de saúde mais eficientes e equânimes.

https://doi.org/10.6063/motricidade.24618

Precision of wearable heart rate to predict oxygen uptake in endurance vs sprint-trained runners
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Garrido, Nuno Domingos

; Aidar, Felipe

; Vilaça-Alves, José

; Oliveira, Diogo Roberto

; Szabo, Paul

; Reis, Victor Machado

Motricidade

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Dez 2022, Volume 18 Nº 2 Páginas 215 - 218

Resumo: En | Texto: En | PDF: En

ABSTRACT The present study aimed to assess the precision of oxygen uptake with heart rate regression during treadmill running in highly trained runners. Twenty national and international level male runners were divided into two equal groups. Group A was formed of 10 sprinters (31.5± 4.7 years, height 1.74± 0.04 m and mass 61.8± 5.2 kg), and group B comprised 10 endurance runners (25.7± 4.5 years, height 1.77± 0.08 m and mass 71.2± 5.8 kg). Each participant performed six min bouts at a constant velocity on a level treadmill, with each bout at an increased running velocity. The starting velocity was 3.33 m·s-1, with a 0.56 m·s-1 increase in each subsequent bout. VO2 and HR were measured during all runs. Mean peak VO2 and mean peak HR for Group A were, respectively, 71.7± 7.0 mL·kg-1·min-1 and 179.8± 12.7 beats·min-1, while for Group B were 67.3± 4.9 mL·kg-1·min-1 and 198.2± 9.8 beats·min-1. The linearity of the regressions between VO2 and HR in both groups was very high (R2= 0.97 and R2=0.76) with small standard errors of regression. Despite a stronger correlation in endurance-trained athletes, the results of the present study indicate that it is possible to use HR as an indicator of exercise intensity in individuals trained in both speed and longer distances.

https://doi.org/10.6063/motricidade.27172

Acute effects of two HIIT protocols on oxidative responses
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Carvalho, George Franklin Santana de

; Marçal, Anderson Carlos

; Aidar, Felipe José

; Santos, Jymmys Lopes

; Brito, Ciro José

; Getirana-Mota, Márcio

; Lima, Clésio Andrade

; Sampaio, Ricardo Aurélio Carvalho

; Souza, Raphael Fabrício de

; Vieira-Souza, Lucio Marques

Motricidade

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Dez 2022, Volume 18 Nº 2 Páginas 276 - 281

Resumo: En | Texto: En | PDF: En

ABSTRACT The aim of this experimental study was to evaluate acute responses to oxidative stress (OS) after a single session of two HIIT protocols. 24 Wistar rats were divided into three groups (n= 8): sedentary control (SC), HIIT with a 7-minute volume (LW) and HIIT with 14-min (HW). After the protocol, blood was collected for the measurement of uric acid (UA), and the liver and the gastrocnemius muscle were collected for OS assessment by measuring malondialdehyde (MDA) and total antioxidant capacity (FRAP). The LW and HW groups showed a reduction in hepatic MDA (51.9 and 29.9%; p< 0.05) compared to SC. However, the muscle of the HW group increased the MDA (12.6%; p< 0.05) compared to SC. As for FRAP, LW and HW reduced values (78.3 and 75.3%; p< 0.05) compared to SC, respectively. UA in the LW group was higher when compared to SC (64.7%; p< 0.05), HW group was similar to SC (p> 0.05). Among the different HIIT protocols, the LW group showed an increase in UA compared to the HW group (44%; p< 0.05). Compared to SC, the LW and HW groups did not promote acute OS in the liver tissue. However, HW caused OS in muscle tissue after a single exercise session.

https://doi.org/10.6063/motricidade.27710

Análise da aptidão física com a utilização de exergames em jovens futebolistas e não futebolistas: um estudo piloto
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Getirana-Mota, Márcio

; Paz, Ângelo de Almeida

; Vieira-Souza, Lúcio Marques

; Matos, Ricardo Santos

; Rosa, José Lucas Santos

; Costa, Lúcio Flávio Gomes Ribeiro da

; Teles, Luan José Lopes

; Aidar, Felipe José

Motricidade

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Dez 2022, Volume 18 Nº 2 Páginas 230 - 236

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The objective of this research was to identify whether the use of exergames can help improve physical fitness through Burpee and analyse whether exergames can improve agility and spatial-temporal perception in young soccer players and non-players. This is a descriptive exploratory research with qualitative-quantitative data analysis. Participants were children (10.8 ± 1.8 years). For this sample, it was observed that exergames did not promote a significant increase in physical fitness (Group 1 × Group 2= 95%CI (-6.39–6.59), p> 1.00; Group 3 × Group 4= 95%CI (-1.27–3.47), p> 1.00). In contrast, exergames promoted a significant improvement in agility and spatiotemporal perception for group 2 (Agility Pre × Post: Z= -2.828; p= 0.05; Spatiotemporal perception Pre × Post: Z= -2.828; p= 0.05). We understand that exergames did not improve physical fitness in young soccer players and that they also did not provide improvements in agility or spatiotemporal perception. However, for the non-athlete public, there was a significant improvement in agility and spatial-temporal perception.

RESUMO O objetivo desta pesquisa foi identificar se a utilização do exergames pode auxiliar na melhora da aptidão física através do Burpee, como também, analisar se os exergames podem melhorar a agilidade e a percepção espaço-temporal em jovens jogadores de futebol e não jogadores. Esta pesquisa tem caráter exploratório descritivo com analise quali-quantitativa dos dados. Os participantes do estudo foram crianças (10,8± 1,8 anos). Para essa amostra, foi observado que o exergames não promoveu aumento significativo da aptidão física (Grupo 1 × Grupo 2= IC95% (-6,39–6,59), p> 1,00; Grupo 3 × Grupo 4= IC95% (-1,27–3,47), p> 1,00). Em contrapartida, o exergames promoveu melhora significativa da agilidade e da percepção espaço-temporal para o grupo 2 (Agilidade Pré × Pós: Z= -2,828; p= 0,05; Percepção espaço-temporal Pré × Pós: Z= -2,828; p= 0,05). Depreendemos que os exergames não proporciona melhora da aptidão física em jovens jogadores de futebol, e que também não proporcionou melhoras na agilidade ou na percepção espaço-temporal. Porém, para o público não atleta, houve melhora significativa para a agilidade e percepção espaço-temporal.

https://doi.org/10.6063/motricidade.27175

Correlation between creatine kinase (CK) and thermography: a systematic review with meta-analysis
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Santos, Tales Magalhães dos

; Bunn, Priscila dos Santos

; Aidar, Felipe José

; Mello, Danielli Braga de

; Neves, Eduardo Borba

Motricidade

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Set 2022, Volume 18 Nº 3 Páginas 467 - 478

Resumo: En | Texto: En | PDF: En

Abstract This research aimed to investigate the association between the skin temperature variation of the skin identified by thermography and serum CK values in healthy subjects based on a systematic review with meta-analysis. A systematic literature search was performed in June 2021 in the SCOPUS, MEDLINE, and Web of Science databases (2000 to 2021). MeSH and DeCS platforms were used to find the descriptors in English referring to the terms “thermography” and “creatine kinase” with their synonyms (nine and 13, respectively) to find studies, following the PIRT strategy: Participants (healthy subjects); Index Test (thermography); Reference Test (CK collection); Target Condition (having analyzed the results of the Index and Reference Test). A meta-analysis was performed to calculate the association between variables. A total of 483 files were retrieved from the databases, and 13 were selected for analysis (five met the criteria for meta-analysis). Considering the 13 studies reviewed, there is a general balance in obtaining results of CK increase along with skin temperature versus studies that didn’t observe any association between the measures. However, the meta-analysis showed no significant association between the variables analyzed (r= –0.05; p= 0.06; 95%CI –0.11 – 0.00). This result suggests that the result of one test cannot estimate the result of the other. It was concluded that there is no good association between CK levels and thermography results; it’s recommended the use of thermal images in addition to other evaluation methods in order to assist in the determination of special differential diagnoses of musculoskeletal injuries.

https://doi.org/10.6063/motricidade.26751

The influence of the pilates method on the quality of life of its practitioners: a systematic review
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Silveira, Fabrício Sette Abrantes

; Abrantes, Lívia Carvalho Sette

; Moreira, Osvaldo Costa

; Prado Júnior, Pedro Paulo do

; Camilo, Flávio de Jesus

; Aidar, Felipe José

; Pereira, Eveline Torres

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Jun 2022, Volume 18 Nº 1 Páginas 98 - 119

Resumo: En | Texto: En | PDF: En

ABSTRACT Created in Germany by Joseph Pilates in the 1920s, the Pilates Method (PM) uses exercises aiming to improve physical health and mental balance. The present work objective was to verify, through a systematic literature review without delineating languages and dates, the influence of PM on the quality of life (QoL) of its practitioners. Medline, Embase, Web of Science, Scopus, and Google Scholar databases were consulted. The articles were independently selected by two researchers, who also conducted the risk of bias assessment of the included articles. Were identified 2489 articles on the databases, of which 30 were included in the study synthesis. The practice of PM improves the QoL of its practitioners, providing enhanced functional capacity, pain relief, and improvement of emotional aspects in individuals of both sexes, different age groups, and different clinical contexts.

https://doi.org/10.6063/motricidade.25780

10.

High-Intensity Resistance Exercise and Schinus terenbinthifolius Supplementation Attenuate Oxidative Stress and Muscle Damage Biomarkers
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Vieira-Souza, Lucio Marques

; Marçal, Anderson Carlos

; dos-Santos, Jymmys

; Lopes Aidar, Felipe José

; dos-Santos, Samuel Bruno

; de Santana Silva, André Luiz

; Costa Reis, Gracielle

; Santana de Carvalho, George Franklin

; de Souza, Raphael Fabrício

; Tavares dos Santos, Darlan

; Sorbazo Soto, Dany Alexis

; Brito, Ciro José

International Journal of Morphology

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Jun 2022, Volume 40 Nº 3 Páginas 781 - 788

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

SUMMARY: High-intensity physical exercises can cause oxidative stress and muscle damage. Several medicinal plants have been used as antioxidant and anti-inflammatory agents. The present study evaluated high-intensity resistance exercise (HIRE) associated with Schinus Terebentifholius ethanolic extract (EE) on oxidative parameters and muscle damage in Wistar rats. Animals were divided into 04 groups (n=10/group): 1. Control (CG) - animals that did not undergo HIRE and were treated with vehicle (distilled water, orally); 2. Acute exercise (AE) - animals submitted to acute exercise session; 3. Exercise + vehicle (EV) - animals that underwent HIRE and were treated with vehicle and 4. Exercise + extract (EX) animals administered with Schinus terebenthifolius EE (100mg/Kg, orally) and submitted to the exercise session. Schinus terebenthifolius EE showed high in vitro antioxidant activity (13.88 ± 0.36 mg/mL). Before the experimental period, lactate was measured at pre and post moments of AE (p<0.0001) and EX (p<0.0001) groups. After the acute session, the following were evaluated: oxidative stress {malondialdehyde (MDA), sulfhydryl groups (SH) and ferric reducing antioxidant power (FRAP)}, muscle damage (creatine kinase (CK) and lactate dehydrogenase (LDH)), alanine aminotransferase (ALT) and aspartate aminotransferase (AST). In the in vivo analyses of the EX group compared to AE and EV groups, respectively: hepatic (MDA: p<0.0001 and SH: p=0.0033, in both; FRAP: p=0.0011 and p=0.0047), muscle (MDA, SH and FRAP: p<0.0001, in both; CK: p=0.0001 and p<0.0001; LDH: p<0.0001, in both), serum levels (MDA: p=0.0003, p=0.0012, SH: p=0.0056, p=0.0200, FRAP: p=0.0017 and p=0.0165) were significant. There was no significant difference in ALT and AST markers. It could be concluded that Schinus terebenthifolius EE associated with HIRE attenuated oxidative stress and muscle damage in rats.

RESUMEN: Los ejercicios físicos de alta intensidad pueden causar estrés oxidativo y daño muscular. Varias plantas medicinales se han utilizado como agentes antioxidantes y antiinflamatorios. El presente estudio evaluó el ejercicio de resistencia de alta intensidad (HIRE) asociado con el extracto etanólico (EE) de Schinus terebentifholius sobre los parámetros oxidativos y el daño muscular en ratas Wistar. Los animales se dividieron en 4 grupos (n=10/grupo): 1. Control (GC) - animales que no se sometieron a HIRE y fueron tratados con vehículo (agua destilada, por vía oral); 2. Ejercicio agudo (AE) - animales sometidos a sesión de ejercicio agudo; 3. Ejercicio + vehículo (EV) - animales que se sometieron a HIRE y fueron tratados con vehículo y 4. Ejercicio + extracto (EX) animales administrados con Schinus terebenthifolius EE (100 mg/kg, por vía oral) y sometidos a la sesión de ejercicio. Schinus terebenthifolius EE mostró una alta actividad antioxidante in vitro (13,88 ± 0,36 mg/mL). Antes del período experimental, se midió el lactato en los momentos pre y post de los grupos AE (p<0,0001) y EX (p<0,0001). Tras la sesión aguda, se evaluaron: el estrés oxidativo malondialdehído (MDA), grupos sulfhidrilo (SH) y poder antioxidante reductor férrico (FRAP), daño muscular (creatina quinasa (CK) y lactato deshidrogenasa (LDH)), alanina aminotransferasa (ALT) y aspartato aminotransferasa (AST). En los análisis in vivo del grupo EX frente a los grupos AE y EV, respectivamente: hepático (MDA: p<0,0001 y SH: p=0,0033, en ambos; FRAP: p=0,0011 y p=0,0047), muscular (MDA, SH y FRAP: p<0,0001, en ambos; CK: p=0,0001 y p<0,0001; LDH: p<0,0001, en ambos), niveles séricos (MDA: p=0,0003, p=0,0012, SH: p=0,0056, p=0,0200, FRAP: p=0,0017 y p=0,0165) fueron significativas. No hubo diferencia significativa en los marcadores ALT y AST. Se podría concluir que Schinus terebenthifolius EE asociado con HIRE atenuó el estrés oxidativo y el daño muscular en ratas.

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11.

Effects of HIIT Associated with Coutoubea spicata Supplementation on Tissue and Oxidative damage Biomarkers in Wistar Rats
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dos-Santos, Jessica Denielle Matos

; dos-Santos, Jymmys Lopes

; Vieira-Souza, Lucio Marques

; de-Oliveira, José Uilien

; Sena-Junior, Ailton Santos

; de-Lima, Clésio Andrade

; Aidar, Felipe José

; Marçal, Anderson Carlos

; de-Araújo, Silvan Silva

International Journal of Morphology

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Fev 2022, Volume 40 Nº 1 Páginas 204 - 209

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

SUMMARY: This study aimed to evaluate the effects of six weeks of HIIT on tissue and oxidative damage markers in rats supplemented with Coutoubea spicata fraction. Thirty-two male Wistar rats were divided into 4 groups: Baseline (GB); supplemented with 100 mg/kg of Coutoubea spicata fraction (GSCS); exercised for 6 weeks with the HIIT protocol (GH); supplemented with 100 mg/kg of Coutoubea spicata fraction + HIIT for 6 weeks (GHCS). Exercised animals performed the HIIT protocol (2 x 2). Tissue damage CK, LDH, ALT and AST markers in plasma were analyzed, as well as oxidative stress MDA and SH biomarkers in plasma and in cardiac, hepatic and muscle tissues. The results showed that CK, LDH, AST and ALT enzymes showed increase in GH when compared to GB (p<0.0001). However, CK, AST and ALT markers reduced their concentrations in GHCS when compared to GH (p<0.0001), indicating that Coutoubea spicata supplementation attenuated the damage in muscle and liver tissues induced by HIIT. Plasma, liver and muscle MDA showed increase in GH after HIIT sessions; however, when compared to GHCS, it showed reduced levels (p<0.0001). SH was elevated in the GH group when compared to GB in plasma and liver tissues (p<0.0001); in contrast, reduction in GHCS when compared to GH was observed in plasma, liver and cardiac tissues, demonstrating the redox effect of HIIT on some tissues. Thus, our findings showed that Coutoubea spicata has antioxidant activity, reducing oxidative damage markers and consequently tissue damage in healthy Wistar rats after HIIT protocol, but it also demonstrated redox balance after analyzing oxidative stress markers.

RESUMEN: Este estudio tuvo como objetivo evaluar los efectos de HIIT en los marcadores de daño tisular y oxidativo en ratas suplementadas con Coutoubea spicata durante seis semanas. Treinta y dos ratas Wistar macho se dividieron en 4 grupos: línea de base (GB); suplementados con 100 mg/kg de fracción de Coutoubea spicata (GSCS); ejercitados durante 6 semanas con el protocolo HIIT (GH); suplementado con 100 mg/kg de fracción de Coutoubea spicata + HIIT durante 6 semanas (GHCS). Los animales ejercitados realizaron el protocolo HIIT (2x2). Se analizaron los marcadores de daño tisular CK, LDH, ALT y AST en plasma, así como los biomarcadores de estrés oxidativo MDA y SH en plasma y en tejidos cardiaco, hepático y muscular. Los resultados indicaron que las enzimas CK, LDH, AST y ALT mostraron aumento en GH en comparación con GB (p<0,0001). Sin embargo, los marcadores CK, AST y ALT redujeron sus concentraciones en GHCS en comparación con GH (p<0,0001), lo que indica que la suplementación con Coutoubea spicata atenuó el daño en los tejidos musculares y hepáticos inducido por HIIT. La MDA de plasma, hígado y músculo mostró un aumento en la GH después de las sesiones de HIIT; sin embargo, en comparación con GHCS, mostró niveles reducidos (p<0,0001). Se observó SH elevado en el grupo de GH en comparación con GB en plasma y tejidos hepáticos (p<0,0001); en contraste, se observó una reducción en GHCS en comparación con GH en plasma, hígado y tejidos cardíacos, lo que demuestra el efecto redox de HIIT en algunos tejidos. Por lo tanto, nuestros hallazgos mostraron que Coutoubea spicata tiene actividad antioxidante, con reducción de los marcadores de daño oxidativo y, en consecuencia, el daño tisular en ratas Wistar sanas después del protocolo HIIT, pero además demostró el equilibrio redox después de analizar los marcadores de estrés oxidativo.

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12.

Relationships between take-off speed and performance in F-44 and F-46 paralympic discus throwers
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Banja Fernandes, Túlio Luiz

; Oliveira, Saulo Fernandes Melo de

; Oliveira, José Igor Vasconcelos de

; Martins, Felipe José Aidar

; Ramos Júnior, Valdir Rodrigues

; Costa, Manoel da Cunha

; Tashiro, Tetsuo

Revista Brasileira de Ciências do Esporte

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2022, Volume 44 elocation e008021

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO O presente estudo teve como objetivo a análise do lançamento de disco em atletas paralímpicos de duas classes funcionais (CFs). Sete atletas de duas classes F-44 (N=4) e F-46 (N=3) executaram 3 lançamentos cada durante uma competição regional, e foram avaliados por meio de cinemetria 3D. Os atletas avaliados apresentaram uma técnica de lançamento semelhante, com movimento de preparação em direção oposta ao lançamento que antecedia o arremate. Na classe F-44 houve uma fraca correlação entre a velocidade de decolagem e o alcance do disco (r= 0,15; p>0,05). Na F-46 houve forte correlação entre a velocidade de decolagem e o alcance (r= 0,77; p=0,014). Conclui-se que atletas das CFs avaliadas apresentam diferenças importantes em termos de desempenho.

ABSTRACT This study aimed to analyze discus throwing in Paralympic athletes from two functional classes (FCs). Seven athletes from two classes F-44 (N=4) and F-46 (N=3) performed three throws each during a regional competition and were evaluated through 3D kinemetry. The assessed athletes presented a similar throwing technique, with a preparation movement opposite to the throw preceding the shot. Class F-44 showed a weak correlation between take-off speed and range (r= 0.15; p>0.05). F-46 showed a strong correlation between take-off speed and range (r=0.77; p=0.014). We conclude that athletes from the assessed FCs present important differences in terms of performance.

RESUMEN El presente estudio tuvo como objetivo analizar el lanzamiento de disco en atletas paralímpicos de dos clases funcionales (FC). Siete atletas de dos clases F-44 (N = 4) y F-46 (N = 3) realizaron 3 lanzamientos cada uno durante una competencia regional, y fueron evaluados usando cinemetría 3D. Los deportistas evaluados presentaron una técnica de lanzamiento similar, con un movimiento de preparación en sentido contrario al lanzamiento que precedió al tiro. En la clase F-44 hubo una correlación débil entre la velocidad de despegue y el alcance del disco (r = 0,15; p> 0,05). En el F-46 hubo una fuerte correlación entre la velocidad de despegue y el alcance (r = 0,77; p = 0,014). Se concluye que los deportistas de los CF evaluados presentan importantes diferencias en cuanto a rendimiento.

https://doi.org/10.1590/rbce.44.e008021

13.

Implications for Clinical Practice from a Multicenter Survey of Heart Failure Management Centers
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Bocchi, Edimar Alcides

; Moreira, Henrique Turin

; Nakamuta, Juliana Sanajotti

; Simões, Marcus Vinicius

; Casas, Alberto de Almeida Las

; Costa, Altamiro Reis da

; Assis, Amberson Vieira de

; Durães, André Rodrigues

; Pereira-Barretto, Antonio Carlos

; Ravessa, Antonio Delduque de Araujo

; Macedo, Ariane Vieira Scarlatelli

; Biselli, Bruno

; Pinto, Carolina Maria Nogueira

; Filho, Conrado Roberto Hoffmann

; Costantini, Costantino Roberto

; Almeida, Dirceu Rodrigues

; Santos Jr, Edval Gomes dos

; Soliva Junior, Erwin

; Figueiredo, Estevão Lanna

; Albuquerque, Felipe Neves de

; Paulitsch, Felipe

; Neuenschwander, Fernando Carvalho

; Figueiredo Neto, José Albuquerque de

; Brito, Flavio de Souza

; Lopes, Heno Ferreira

; Villacorta, Humberto

; Souza Neto, João David de

; Sepulveda, João Mariano

; Ayoub, José Carlos Aidar

; Vilela-Martin, José F.

; Cardoso, Juliano Novaes

; Uemura, Laercio

; Moura, Lidia Zytynski

; Maia, Lilia Nigro

; Oliveira, Lucia Brandão de

; Maia, Lucimir

; Silva, Luís Beck da

; Gowdak, Luís Henrique Wolff

; Danzmann, Luiz Claudio

; Andrade, Marcus

; Braile-Sternieri, Maria Christiane Valeria Braga

; Moreira, Maria da Consolação Vieira

; França Neto, Olimpio R

; Filho, Otavio Rizzi Coelho

; Esteves, Paulo Frederico

; Raupp-da-Rosa, Priscila

; Silva, Ricardo Jorge de Queiroz e

; Mourilhe-Rocha, Ricardo

; Viégas, Ruy Felipe Melo

; Rassi, Salvador

; Mangili, Sandrigo

; Kaiser, Sergio Emanuel

; Martins, Silvia Marinho

; Kawabata, Vitor Sergio

Clinics

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2021, Volume 76 elocation e1991

Resumo: En | Texto: En | PDF: En

OBJECTIVES: This observational, cross-sectional study based aimed to test whether heart failure (HF)-disease management program (DMP) components are influencing care and clinical decision-making in Brazil. METHODS: The survey respondents were cardiologists recommended by experts in the field and invited to participate in the survey via printed form or email. The survey consisted of 29 questions addressing site demographics, public versus private infrastructure, HF baseline data of patients, clinical management of HF, performance indicators, and perceptions about HF treatment. RESULTS: Data were obtained from 98 centers (58% public and 42% private practice) distributed across Brazil. Public HF-DMPs compared to private HF-DMP were associated with a higher percentage of HF-DMP-dedicated services (79% vs 24%; OR: 12, 95% CI: 94-34), multidisciplinary HF (MHF)-DMP [84% vs 65%; OR: 3; 95% CI: 1-8), HF educational programs (49% vs 18%; OR: 4; 95% CI: 1-2), written instructions before hospital discharge (83% vs 76%; OR: 1; 95% CI: 0-5), rehabilitation (69% vs 39%; OR: 3; 95% CI: 1-9), monitoring (44% vs 29%; OR: 2; 95% CI: 1-5), guideline-directed medical therapy-HF use (94% vs 85%; OR: 3; 95% CI: 0-15), and less B-type natriuretic peptide (BNP) dosage (73% vs 88%; OR: 3; 95% CI: 1-9), and key performance indicators (37% vs 60%; OR: 3; 95% CI: 1-7). In comparison to non- MHF-DMP, MHF-DMP was associated with more educational initiatives (42% vs 6%; OR: 12; 95% CI: 1-97), written instructions (83% vs 68%; OR: 2: 95% CI: 1-7), rehabilitation (69% vs 17%; OR: 11; 95% CI: 3-44), monitoring (47% vs 6%; OR: 14; 95% CI: 2-115), GDMT-HF (92% vs 83%; OR: 3; 95% CI: 0-15). In addition, there were less use of BNP as a biomarker (70% vs 84%; OR: 2; 95% CI: 1-8) and key performance indicators (35% vs 51%; OR: 2; 95% CI: 91,6) in the non-MHF group. Physicians considered changing or introducing new medications mostly when patients were hospitalized or when observing worsening disease and/or symptoms. Adherence to drug treatment and non-drug treatment factors were the greatest medical problems associated with HF treatment. CONCLUSION: HF-DMPs are highly heterogeneous. New strategies for HF care should consider the present study highlights and clinical decision-making processes to improve HF patient care.

https://doi.org/10.6061/clinics/2021/e1991 870 downloads

14.

Biomarker responses of cardiac oxidative stress to high intensity interval training in rats
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Vieira-Souza, Lúcio Marques

; Santos, Jymmys Lopes dos

; Marçal, Anderson Carlos

; Voltarelli, Fabrício Azevedo

; Aidar, Felipe José

; Miguel-dos-Santos, Rodrigo

; Costa, Roas de Araújo

; Matos, Dihogo Gama de

; Santos, Sandra Lauton

; Araújo, Silvan Silva de

Motriz: Revista de Educação Física

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2021, Volume 27 elocation e1021021420

Resumo: En | Texto: En | PDF: En

Abstract Aim: The present study aimed to verify the cardiac oxidative stress biomarker responses to high-intensity interval training (HIIT) in rats. Methods: Sixteen male Wistar rats weighing 250 to 300 g were equally divided into two groups (8 animals/group): sedentary control (SC) and trained group (HIIT). The exercise protocol consisted of high-intensity swimming (14% of body weight, 20 s of activity with 10 s of pause performed 14 times) which was performed for 12 consecutive days. Results: The cardiac tissue concentrations of malondialdehyde and carbonylated proteins showed no significant changes; on the other hand, hydroperoxide levels were higher in the HIIT group than in the SC group. The activities of superoxide dismutase, catalase, and glutathione peroxidase enzymes and the levels of reduced glutathione and sulfhydryl remained unchanged. Conclusion: It is possible to conclude that short-term high-intensity interval training induces changes in the cardiac oxidative stress biomarker but with no effect on the antioxidant enzymes.

https://doi.org/10.1590/s1980-65742021021420 318 downloads

15.

Analysis of oxidative stress in Wistar rats submitted to high-intensity interval training
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Souza, Lúcio Marques Vieira

; Aidar, Felipe José

; Matos, Dihogo Gama de

; Marçal, Anderson Carlos

; Souza, Raphael Fabricio de

; Santos, Jymmys Lopes dos

; Wartha, Elma Regina Silva de Andrade

; Silva, Albená Nunes da

; Estevam, Charles dos Santos

; Araújo, Silvan Silva de

Motricidade

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Set 2020, Volume 16 Nº 3 Páginas 174 - 181

Resumo: En | Texto: En | PDF: En

ABSTRACT Physical exercise is a known factor that can promote oxidative stress and may result in cellular damage if not neutralized by antioxidant mechanisms. This study aimed to determine if the level of hepatic oxidative stress resulting from high-intensity interval training (HIIT) is affected by the frequency pattern (consecutive vs. non-consecutive) of the training sessions. Thirty-two Wistar rats were divided equally into four groups: two control groups, (CS1) and (CS2), remained sedentary throughout the experiment, and two test groups, (CT1) and (CT2), and were submitted to HIIT for 12 consecutive and non-consecutive (12 sessions, 3 times/wk over four weeks) days, respectively. There were no significant differences in markers of oxidative damage measured in hepatic tissue (TBARS) and markers of antioxidant activity (Sulfhydryl, FRAP), as well as markers of hepatic damage (AST and ALT) and antioxidant defense (Uric Acid) measured in plasma of both HIIT groups after training compared to the control groups. The results indicate that both HIIT performed for 12 consecutive and non-consecutive sessions did not promote hepatic oxidative damage in rats.

https://doi.org/10.6063/motricidade.21310 66 downloads

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