Pesquisa | SciELO

ABSTRACT BACKGROUND: Congenital vascular anomalies and hemangiomas (CVAH) such as infantile hemangiomas, port-wine stains and brain arteriovenous malformations (AVMs) impair patients’ lives and may require treatment if complications occur. However, a great variety of treatments for those conditions exist and the best interventions remain under discussion. OBJECTIVE: To summarize Cochrane systematic review (SR) evidence on treatments for CVAH. DESIGN AND SETTING: Review of SRs conducted in the Division of Vascular and Endovascular Surgery of Universidade Federal de São Paulo, Brazil. METHODS: A broad search was conducted on March 9, 2021, in the Cochrane Database of Systematic Reviews to retrieve any Cochrane SRs that assessed treatments for CVAH. The key characteristics and results of all SRs included were summarized and discussed. RESULTS: A total of three SRs fulfilled the inclusion criteria and were presented as a qualitative synthesis. One SR reported a significant clinical reduction of skin redness by at least 20%, with more pain, among 103 participants with port-wine stains. One SR reported that propranolol improved the likelihood of clearance 13 to 16-fold among 312 children with hemangiomas. One SR reported that the relative risk of death or dependence was 2.53 times greater in the intervention arm than with conservative management, among 218 participants with brain AVMs. CONCLUSION: Cochrane reviews suggest that treatment of port-wine stains with pulsed-dye laser improves redness; propranolol remains the best option for infantile hemangiomas; and conservative management seems to be superior to surgical intervention for treating brain AVMs.

https://doi.org/10.1590/1516-3180.2021.0374.r2.15092021

COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.

; Rocco, Isadora

; Pimentel, Wallace S.

; Pinheiro, Aislan H. B.

; Souza, Paulo M. S.

; Costa, Luiz A. A.

; Teixeira, Marjory M. P.

; Ohashi, Leonardo P.

; Bublitz, Caroline

; Begot, Isis

; Moreira, Rita Simone L

; Hossne Jr, Nelson A.

; Vargas, Guilherme F.

; Branco, João Nelson R.

; Teles, Carlos A.

; Medeiros, Eduardo A. S.

; Sáfadi, Camila

; Rampinelli, Amândio

; Moratelli Neto, Leopoldo

; Rosado, Anderson Rosa

; Mesacasa, Franciele Kuhn

; Capriata, Ismael Escobar

; Segalote, Rodrigo Coelho

; Palmieri, Deborah Louize da Rocha Vianna

; Jardim, Amanda Cristina Mendes

; Vianna, Diego Sarty

; Coutinho, Joaquim Henrique de Souza Aguiar

; Jazbik, João Carlos

; Coutinho, Henrique Madureira da Rocha

; Kikuta, Gustavo

; Almeida, Zely Sant'Anna Marotti de

; Feguri, Gibran Roder

; Lima, Paulo Ruiz Lucio de

; Franco, Anna Carolina

; Borges, Danilo de Cerqueira

; Cruz, Felipe Ramos Honorato De La

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Goraieb, Lilian

; Postigo, Karolyne Barroca Sanches

; Jucá, Fabiano Gonçalves

; Oliveira, Fátima Rosane de Almeida

; Souza, Rafael Bezerra de

; Zilli, Alexandre Cabral

; Mas, Raul Gaston Sanchez

; Bettiati Junior, Luiz Carlos

; Tranchesi, Ricardo

; Bertini Jr, Ayrton

; Franco, Leandro Vieira

; Fernandes, Priscila

; Oliveira, Fabiana

; Moraes Jr, Roberto

; Araújo, Thiago Cavalcanti Vila Nova de

; Braga, Otávio Penna

; Pedrosa Sobrinho, Antônio Cavalcanti

; Teixeira, Roberta Tavares Barreto

; Camboim, Irla Lavor Lucena

; Gomes, Eduardo Nascimento

; Reis, Pedro Horigushi

; Garcia, Luara Piovan

; Scorsioni, Nelson Henrique Goes

; Lago, Roberto

; Guizilini, Solange

Brazilian Journal of Cardiovascular Surgery

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Dez 2021, Volume 36 Nº 6 Páginas 725 - 735

Resumo: En | Texto: En | PDF: En

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

https://doi.org/10.21470/1678-9741-2021-0960

Device for Streptavidin Detection Using LSPR and Electrochemical Transductions on the same Platform
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Fressatti, Maria G. V.

; Cabral Jr., Bento P.

; Oliveira, Jean H. de

; Buzzetti, Paulo H. M.

; Radovanovic, Eduardo

; Monteiro, Johny P.

; Girotto, Emerson M.

Journal of the Brazilian Chemical Society

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Abr 2021, Volume 32 Nº 4 Páginas 777 - 785

Resumo: En | Texto: En | PDF: En

Research in biosensing currently occupies an important role among biomolecular detection techniques, especially with respect to medical diagnoses. Is this sense, the development of biosensors based on the localized surface plasmon resonance (an optical transducer) or electrochemical transductions have been highlighted. However, optical and electrochemical detection working together enable more versatile detections in biosensing. Thus, we propose a dual sensor, which incorporates these two mechanisms on the same platform. The sensor shared the same transducer that was based on a glass-indium thin oxide (ITO) surface covered with gold nanoparticles. The transducer was prepared by the immobilization of gold nanoparticles on (3-aminopropyl)triethoxysilane-activated glass-ITO. The substrate ability to respond to physical surface variations was assessed. For this, measurements of the gold nanoparticles band redshift (plasmonic transduction) and charge transfer resistance from impedance spectra (electrochemical transduction) were performed. The platform was able to detect streptavidin immobilized on the surface by both mechanisms demonstrating its applicability as a device for biodetection in dual detection mode.

https://doi.org/10.21577/0103-5053.20200229 153 downloads

New Strategy for Streptavidin Detection Using AuNRs/PAAm Hydrogel Composites
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Oliveira, Jean H. de

; Monteiro, Johny P.

; Buzzetti, Paulo H. M.

; Cabral Júnior, Bento P.

; Radovanovic, Eduardo

; Girotto, Emerson M.

Journal of the Brazilian Chemical Society

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Set 2020, Volume 31 Nº 9 Páginas 1771 - 1777

Resumo: En | Texto: En | PDF: En

Localized surface plasmon resonance (LSPR) is a collective oscillation of free electrons induced by the incident light in nanometric surfaces of conductive materials. Gold nanorods (AuNRs) have been studied for plasmonic devices due to their anisotropic properties. Herein, we report the construction of a specific biosensor using polyacrylamide (PAAm) as the gold nanorods support and test its efficiency with specific streptavidin interaction using biotinylated substrates. First, the hydrogels were synthesized by electropolymerization using cyclic voltammetry on ITO/glass substrates and swallowed with AuNRs. The AuNRs were characterized by visible absorption spectroscopy and transmission electron microscopy. The substrates were characterized by scanning electron microscopy and their plasmonic sensitivities were evaluated using sucrose solutions with different concentrations. The results showed a sensitivity of ca. 226.4 nm RIU-1 with linear correlation of 0.9974. Furthermore, this composite presented reliable detection of the streptavidin biomolecule in the gold surface with good signal-to-noise ratio (SNR).

https://doi.org/10.21577/0103-5053.20200032 268 downloads

[SciELO Preprints] - Plant community dynamics in an urban forest fragment of the São Paulo Metropolitan Area, Brazil
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Kondrat, Hebert Aragaki, Sonia Gomes, Eduardo Pereira Cabral

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Data de publicação: 2020-05-16

Resumo: En Pt

We present a synthesis (2006-2012) of plant community dynamics in an area (1 ha) of the largest remnant of Atlantic Rain Forest surrounded by São Paulo city. Plants with ≥ 2.5 cm dbh, including the climbers, were sampled in 10 transects (2 × 50 m), and the smaller (> 1 m height, < 2.5 cm dbh) in 10 subtransects (1 × 50 m). We sampled 901 individuals, 125 species (38 families), 83 classified as late-successional species, 12 threatened with extinction and 56 absent in the area management plan, some Endangered (EN) species. The climbers were the most dynamics, they had the largest decrease in basal area; and the larger (> 5.0 cm dbh) and shorter (< 2.5 cm dbh) trees had the highest mortality rates of the shrub-tree synusia. Late species regeneration was predominant. The studied forest showed progression towards more mature successional stages in the monitoring period.

Nós apresentamos uma síntese (2006-2012) da dinâmica da comunidade vegetal em uma área (1 ha) do maior remanescente de Mata Atlântica cercado pela cidade de São Paulo. As plantas com dap ≥ 2,5 cm, incluindo as trepadeiras, foram amostradas em 10 transectos (2 × 50 m) e as menores (altura > 1 m, dap < 2,5 cm) em 10 subtransectos (1 × 50 m). Nós amostramos 901 indivíduos, 125 espécies (38 famílias), 83 classificadas como tardias, 12 ameaçadas e 56 ausentes no plano de manejo da área, algumas Em Perigo (EN) de extinção. As trepadeiras foram as mais dinâmicas, com a maior redução de área basal; e as árvores maiores (dap > 5,0 cm) e menores (dap < 2,5 cm) tiveram a maior mortalidade da sinúsia arbórea. A regeneração de espécies tardias foi a predominante. No período monitorado, a floresta estudada apresentou progressão para estádios sucessionais mais maduros.

https://doi.org/10.1590/2236-8906-34/2019

Dengue associated with severe cutaneous leukocytoclastic vasculitis and pericardial effusion: a case report
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Costa, Laurisson Albuquerque da

; Santos, Eduardo Feitosa

; Feitoza, Erielly Maria Bezerra Araújo

; Yamashita, Miyuki

; Andrade, Joyce Cabral

; Sousa, Pedro Vinicius Leite de

Revista do Instituto de Medicina Tropical de São Paulo

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2020, Volume 62 elocation e101

Resumo: En | Texto: En | PDF: En

ABSTRACT Dengue is a viral disease, caused by an arbovirus of the genus Flavivirus. In Brazil, its incidence rate is high with a broad clinical spectrum. This report discusses a rare case of dengue associated with cutaneous leukocytoclastic vasculitis and pericardial effusion with eminence of cardiac tamponade in a previously healthy patient with no comorbidities. The serology for dengue was positive and the histopathological analysis of the cutaneous lesions confirmed the diagnosis of leukocytoclastic vasculitis. After receiving treatment, the patient’s condition greatly improved.

https://doi.org/10.1590/s1678-9946202062101 292 downloads

Vitis Labrusca L. grapes cultivars under hydric stress in protected cultivation
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Miguel Filho, Gentil Luiz

; Marques, Douglas José

; Souza, Paulo Sergio de

; Aparecido, Lucas Eduardo de Oliveira

; Cabral Neto, Luciano Dias

Revista Brasileira de Fruticultura

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2020, Volume 42 Nº 4 elocation e-009

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A ampliação da fronteira vitícola brasileira, aliada ao desenvolvimento de novas cultivares adaptadas às diferentes regiões evidenciam a necessidade de maiores informações sobre o manejo da irrigação para novas cultivares, em cultivo protegido. Sendo assim, este trabalho teve como objetivo avaliar cultivares de videira submetidas a diferentes porcentagens de reposição de água no solo, nas condições da região sul de Minas Gerais com o uso de irrigação. O experimento foi implantado e desenvolvido nos anos de 2014 a 2016. O delineamento experimental foi em blocos ao acaso, com cinco repetições. Os tratamentos foram dispostos em parcelas subdivididas, com três porcentagens de reposição (30; 50 e 100 % de reposição necessária de água para esse tipo de solo) e, nas subparcelas, as quatro cultivares de videira pertencentes à espécie Vitis labrusca L. (‘Isabel’, ‘Isabel Precoce’, ‘BRS-Cora’ e ‘BRS-Violeta’). Conclui-se com a pesquisa que as cultivares aumentaram em 75 % o comprimento do cacho, 71 % a massa dos cachos, 39 % a produção de cachos de uva, 52 % o pH, 84 % o teor de sólidos solúveis e 60 % a redução do teor de acidez total com 100 % da reposição de água. A cultivar Isabel precoce nas condições de déficit hídrico obteve os melhores resultados produtivos.

Abstract The expansion of the Brazilian wine border, combined with the development of new cultivars adapted to different regions, highlight the need for more information on irrigation handling for new cultivars in protected cultivation. Therefore, this study aimed to evaluate grapevine cultivars submitted to different percentages of water replacement in the soil in conditions of the Southern region of Minas Gerais with the use of irrigation. The experiment was installed and developed from 2014 to 2016. The experimental design used was random blocks, with five replicates and the treatments were disposed in subdivided plots, with three replacement percentages (30, 50 and 100 % of necessary water replacement for this type of soil) and in the subplots four grapevine cultivars belonging to Vitis labrusca L species. (‘Isabel’, ‘Isabel Precoce’, ‘BRS-Cora’ and ‘BRS-Violeta’). The research concluded that these cultivars increased 75 % the bunch length, 71 % of the bunch weight, 39 % the production of bunch of grapes, 52 % the pH, 84 % the soluble solid content and 60 % the reduction of total acidity content, 60 % to 100 % of water replacement. ‘Isabel precoce’ cultivar in water deficit conditions obtained the best productive results.

https://doi.org/10.1590/0100-29452020009 776 downloads

Plant community dynamics in an urban forest fragment of the São Paulo Metropolitan Area, Brazil
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Kondrat, Hebert

; Aragaki, Sonia

; Gomes, Eduardo Pereira Cabral

Hoehnea

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2020, Volume 47 elocation e342019

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Nós apresentamos uma síntese (2006-2012) da dinâmica da comunidade vegetal em uma área (1 ha) do maior remanescente de Mata Atlântica cercado pela cidade de São Paulo. As plantas com dap ≥ 2,5 cm, incluindo as trepadeiras, foram amostradas em 10 transectos (2 × 50 m) e as menores (altura > 1 m, dap < 2,5 cm) em 10 subtransectos (1 × 50 m). Nós amostramos 901 indivíduos, 125 espécies (38 famílias), 83 classificadas como tardias, 12 ameaçadas e 56 ausentes no plano de manejo da área, algumas Em Perigo (EN) de extinção. As trepadeiras foram as mais dinâmicas, com a maior redução de área basal; e as árvores maiores (dap > 5,0 cm) e menores (dap < 2,5 cm) tiveram a maior mortalidade da sinúsia arbórea. A regeneração de espécies tardias foi a predominante. No período monitorado, a floresta estudada apresentou progressão para estádios sucessionais mais maduros.

ABSTRACT We present a synthesis (2006-2012) of plant community dynamics in an area (1 ha) of the largest remnant of Atlantic Rain Forest surrounded by São Paulo city. Plants with ≥ 2.5 cm dbh, including the climbers, were sampled in 10 transects (2 × 50 m), and the smaller (> 1 m height, < 2.5 cm dbh) in 10 subtransects (1 × 50 m). We sampled 901 individuals, 125 species (38 families), 83 classified as late-successional species, 12 threatened with extinction and 56 absent in the area management plan, some Endangered (EN) species. The climbers were the most dynamics, they had the largest decrease in basal area; and the larger (> 5.0 cm dbh) and shorter (< 2.5 cm dbh) trees had the highest mortality rates of the shrub-tree synusia. Late species regeneration was predominant. The studied forest showed progression towards more mature successional stages in the monitoring period.

https://doi.org/10.1590/2236-8906-34/2019 653 downloads

PAYMENTS FOR ECOSYSTEM SERVICES TO WATER RESOURCES PROTECTION IN PARAÍBA DO SUL ENVIRONMENTAL PROTECTION AREA
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PAVANI, BRUNA FATICHE

; RIBEIRO, THIAGO CARLOS LOPES

; GONÇALVES, DEMERVAL APARECIDO

; SOUSA JÚNIOR, WILSON CABRAL DE

; GIAROLLA, ANGÉLICA

; ARRAUT, EDUARDO MORAES

Ambiente & Sociedade

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2020, Volume 23 elocation e01341

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Um dos benefícios da floresta e do reflorestamento está ligado ao controle da erosão e redução da quantidade de sedimentos em suspensão na água. Este estudo propõe uma metodologia de Pagamentos por Serviços Ecossistêmicos associada a esses benefícios em 24 bacias de abastecimento de água, sob influência da Área de Proteção Ambiental da Bacia do Rio Paraíba do Sul, no Brasil. Para estimar a proteção dos recursos hídricos por meio do reflorestamento, o cenário atual foi comparado a um cenário hipotético, no qual pastagens degradadas são substituídas por florestas. A erosão evitada do solo pode atingir cerca de 40t.ha-1.ano-1. O reflorestamento pode evitar gastos com tratamento de água, disposição de lodo e dragagem em torno de US $ 7,8 milhões por ano. Os valores anuais para PSE variam de US $ 6 a 3.014 por hectare de área reflorestada. Os resultados destacam a importância de valorizar os benefícios dos serviços ecossistêmicos resgatados.

Abstract One of the benefits of forest and reforestation is linked to the erosion control and reduction of the amount of sediments suspended in water. This study proposes a methodology for Payments for Ecosystem Services associated to these benefits in 24 water supply watersheds, under influence of the Paraíba do Sul River Basin Environmental Protected Area, in Brazil. In order to estimate the water resources protection through the reforestation, the current scenario was compared to a hypothetical scenario, in which degraded pasture are replaced by forest. The avoided soil erosion could reach around 40t.ha-1.yr-1. Reforestation can avoid expenditures in water treatment, sludge disposal and dredging around USD 7.8 million per year. Annual values for PES range from USD 6 to 3,014 per hectare of reforested area. The results highlight the importance of valuing the benefits of the ecosystem services rescued.

Resumen Uno de los beneficios del bosque y la reforestación está relacionado con control de erosión y reducción de cantidad de sedimentos suspendidos en el agua. Este estudio propone una metodología para Pagos por Servicios de Ecosistemas asociados a estos beneficios en 24 cuencas hidrográficas, bajo la influencia del Área Protegida Ambiental de la Cuenca del Río Paraíba do Sul, en Brasil. Para estimar la protección de recursos hídricos a través de la reforestación, el escenario actual se comparó con un escenario hipotético, en que los pastos degradados son reemplazados por bosques. La erosión del suelo evitada podría alcanzar 40t.ha-1.ano-1. La reforestación puede evitar gastos en tratamiento del agua, eliminación de lodos y dragado de alrededor de USD 7,8 millones por año. Los valores anuales para PSE varían de USD 6 a 3,014 por hectárea de área reforestada. Los resultados destacan la importancia de valorar los beneficios de servicios ecosistémicos rescatados.

https://doi.org/10.1590/1809-4422asoc20190134r1vu2020l2de 1184 downloads

10.

Physical Activity Levels in Peripheral Artery Disease Patients
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Gerage, Aline Mendes

; Correia, Marilia de Almeida

; Oliveira, Paulo Mesquita Longano de

; Palmeira, Aline Cabral

; Domingues, Wagner Jorge Ribeiro

; Zeratti, Antônio Eduardo

; Puech-Leão, Pedro

; Wolosker, Nelson

; Ritti-Dias, Raphael Mendes

; Cucato, Gabriel Grizzo

Arquivos Brasileiros de Cardiologia

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Set 2019, Volume 113 Nº 3 Páginas 410 - 416

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: Aumentos nos níveis de atividade física diária são recomendados para pacientes com doença arterial periférica (DAP). No entanto, apesar dessa recomendação, pouco se sabe sobre os padrões de atividade física dos pacientes com DAP. Objetivo: Descrever os padrões de atividade física de pacientes com DAP sintomática. Métodos: Este estudo transversal incluiu 174 pacientes com DAP com sintomas de claudicação intermitente. Os pacientes foram submetidos a avaliações clínicas, hemodinâmicas e funcionais. A atividade física foi objetivamente medida por um acelerômetro, e o tempo gasto em atividades sedentárias, de baixa intensidade, de alta intensidade e atividade física moderada-a-vigorosa (AFMV) foi obtido. A análise descritiva foi realizada para resumir os dados dos pacientes e a regressão logística binária foi utilizada para testar as associações brutas e ajustadas entre a adesão à recomendação de atividade física e os fatores sociodemográficos e clínicos. Para todas as análises estatísticas, a significância foi estabelecida em p < 0,05. Resultados: Os pacientes gastaram em média 640 ± 121 min/dia, 269 ± 94 min / dia, 36 ± 27 min/dia e 15 ± 16 min/dia em atividades sedentárias, de baixa intensidade, alta intensidade e AFMV, respectivamente. A prevalência de pacientes que atingiram as recomendações de atividade física foi de 3,4%. Após ajuste para fatores de confusão, observou-se associação inversa significativa entre adesão à recomendação de atividade física e idade (OR = 0,925; p = 0,004), enquanto tempo de doença, ITB e distância total de caminhada não se associaram a esse critério de adesão (p> 0,05). Conclusão: Os padrões de atividade física dos pacientes com DAP são caracterizados por uma grande quantidade de tempo gasto em comportamentos sedentários e um baixo envolvimento na AFMV. Pacientes mais jovens, independentemente dos fatores clínicos e funcionais, apresentaram maior probabilidade de atender às recomendações atuais de atividade física.

Abstract Background: Increases in daily physical activity levels is recommended for patients with peripheral artery disease (PAD). However, despite this recommendation, little is known about the physical activity patterns of PAD patients. Objective: To describe the physical activity patterns of patients with symptomatic peripheral artery (PAD) disease. Methods: This cross-sectional study included 174 PAD patients with intermittent claudication symptoms. Patients were submitted to clinical, hemodynamic and functional evaluations. Physical activity was objectively measured by an accelerometer, and the time spent in sedentary, low-light, high-light and moderate-vigorous physical activities (MVPA) were obtained. Descriptive analysis was performed to summarize patient data and binary logistic regression was used to test the crude and adjusted associations between adherence to physical activity recommendation and sociodemographic and clinical factors. For all the statistical analyses, significance was accepted at p < 0.05. Results: Patients spent in average of 640 ± 121 min/day, 269 ± 94 min/day, 36 ± 27 min/day and 15 ± 16 min/day in sedentary, low-light, high-light and MVPA, respectively. The prevalence of patients who achieved physical activity recommendations was 3.4%. After adjustment for confounders, a significant inverse association was observed between adherence to physical activity recommendation and age (OR = 0.925; p = 0.004), while time of disease, ankle brachial index and total walking distance were not associated with this adherence criteria (p > 0.05). Conclusion: The patterns of physical activity of PAD patients are characterized by a large amount of time spent in sedentary behaviors and a low engagement in MVPA. Younger patients, regardless of the clinical and functional factors, were more likely to meet the current physical activity recommendations.

https://doi.org/10.5935/abc.20190142 1420 downloads

11.

In vitro ovicidal and larvicidal activity of Carica papaya seed hexane extract against Strongyloides venezuelensis
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Cabral, Eduardo Ramos Martins

; Moraes, Dayane

; Levenhagen, Marcelo Arantes

; Matos, Ricardo Alexandre Figueiredo de

; Costa-Cruz, Julia Maria

; Rodrigues, Rosângela Maria

Revista do Instituto de Medicina Tropical de São Paulo

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2019, Volume 61 elocation e59

Resumo: En | Texto: En | PDF: En

ABSTRACT Strongyloidiasis is a human parasitic disease caused by the helminth Strongyloides stercoralis whose treatment is particularly difficult in immunosuppressed patients due to their low responsiveness to conventional therapy. Carica papaya and its isolated compounds benzyl isothiocyanate, carpaine and carpasemine are promising compound for the treatment of Strongyloides infections due to their anthelmintic action. This study aims to examine the in vitro ovicidal and larvicidal activity of C. papaya seed hexane extract against Strongyloides venezuelensis, using egg hatching tests and larval motility tests as efficiency markers. The crude extract at the concentrations of 566 – 0.0566 mg/mL or the control with albendazole (0.025 mg/mL) and negative controls (water and PBS) were incubated with an equal volume of egg suspension (± 50 specimens) followed by counting of the specimens after 48 h. The same extract and dilutions were added to L3 larvae suspensions (±50 specimens) followed by analysis of larvae viability after 24, 48, and 72 h. The extract inhibited egg hatching with high efficiency at concentrations of 56.6 mg/mL (95.74%) and 5.66 mg/mL (92.16%). At the concentrations of 566 mg/mL (100%) and 56.66 mg/mL (97.32%), the extract inhibited larval motility as effectively as ivermectin (0.316 mg/mL; 100%), and more effectively than the other dilutions and the negative controls. The larvicidal effect depended on the extract concentration, but not on the treatment period. Therefore, C. papaya seed hexane extract has anthelmintic potential against S. venezuelensis and is a promising compound for the development of phytotherapies to treat strongyloidiasis.

https://doi.org/10.1590/s1678-9946201961059 1180 downloads

12.

Riqueza de fungos ingoldianos e de fungos aquático-facultativos no Parque Municipal do Carmo, São Paulo, SP, Brasil
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Schoenlein-Crusius, Iracema H.

; Moreira, Carolina Gasch

; Gomes, Eduardo Pereira Cabral

Hoehnea

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Set 2018, Volume 45 Nº 3 Páginas 379 - 393

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO A riqueza de fungos ingoldianos, fungos aquático-facultativos e algumas variáveis abióticas foram avaliadas em alguns lagos e riachos no Parque do Carmo na cidade de São Paulo, SP. Coletas mensais de folhedo misto submerso foram realizadas de março de 2007 a junho de 2009. Adicionalmente, a temperatura, pH, oxigênio dissolvido e a condutividade foram medidos com um equipamento multisonda. No laboratório, as folhas foram lavadas, divididas em fragmentos (1 cm2), incubadas em água destilada esterilizada (30 dias, 22 °C) e analisadas microscopicamente para identificação dos táxons com base na literatura pertinente. Foram obtidos 35 táxons, divididos em 22 fungos ingoldianos, (mais frequentes nos córregos) e 13 fungos aquático-facultativos (mais frequentes nos lagos). A riqueza da micota nas épocas secas e frias foi semelhante a das épocas chuvosas e quentes, porém diminuiu nas épocas secas e quentes. O tipo de estação climática exerceu maior influência na riqueza de fungos do que o tipo de local de coleta, com correlações positivas entre a micota, a temperatura e a condutividade elétrica da água. O Parque do Carmo apresenta riqueza considerável de fungos ingoldianos e aquático-facultativos, oferecendo ambientes aquáticos interessantes para estudos sobre a influência climática sazonal na micota aquática urbana.

ABSTRACT The richness of ingoldian fungi, aquatic facultative fungi, and some abiotic variables were evaluated in some lakes and streams of the Parque do Carmo, in the city of São Paulo, in São Paulo State. Monthly collections of submerged mixed leaf samples were carried out from March 2007 to June 2009. Additionally, the temperature, pH, dissolved oxygen and conductivity were measured using a multi-probe. In the laboratory, leaves were washed, divided into fragments (1 cm2), incubated in sterile distilled water (30 days, 22 °C) and analyzed under microscope for fungal identification by means of the current literature. Thirty-five fungal taxa were obtained, which were divided into 22 ingoldian fungi (more frequent in the streams), and 13 aquatic facultative fungi (more frequent in the lakes). The richness of the mycota in the dry and cold seasons was similar to that of the rainy and hot seasons, but it decreased in the dry and hot periods. The climatic season had a greater influence on fungal richness than the type of collection site, with positive correlations between the mycota, the temperature and the electrical conductivity of the water. The Parque do Carmo presents a considerable richness of ingoldian and aquatic facultative fungi, and offers interesting aquatic environments for studies related to the seasonal climatic influence on the urban aquatic mycota.

https://doi.org/10.1590/2236-8906-24/2018 560 downloads

13.

Agroclimatic zoning for urucum crops in the state of Minas Gerais, Brazil
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Aparecido, Lucas Eduardo de Oliveira

; Rolim, Glauco de Souza

; Moraes, José Reinaldo da Silva Cabral de

; Rocha, Hélio Gallo

; Lense, Guilherme Henrique Expedito

; Souza, Paulo Sergio

Bragantia

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Mar 2018, Volume 77 Nº 1 Páginas 193 - 200

Resumo: En | Texto: En | PDF: En

ABSTRACT Hardier crops are needed in the arid regions of the Brazilian state of Minas Gerais, and annatto (Bixa orellana L.) is a good candidate. Producers, however, do not know if their areas are suitable for its cultivation and so are not investing in its implementation. Agroclimatic zoning would provide guidance to the producers. Identifying potential areas for the production of this crop would thus contribute to the agroclimatic zoning of B. orellana in Minas Gerais. We collected data for air temperature and precipitation from 852 meteorological stations in the state to classify regions as suitable, marginally suitable, or unsuitable for the crop. Suitable regions had an air temperature between 22 and 27 °C and precipitation between 800 and 1600 mm.y-1. Marginally suitable regions had an air temperature between 22 and 27 °C and precipitation less than 800 mm.y-1. Unsuitable regions had air temperature less than 22 °C or greater than 27 °C. A geographic information system was used for the spatial interpolation of air temperature and precipitation for all meteorological stations using kriging. The agroclimatic zoning of annatto crops for Minas Gerais was obtained by interpolating the two maps, air temperature and precipitation. Minas Gerais has great potential for urucum production, and agroclimatic zoning enabled the classification of regions by climatic suitability. The northern, western, northwestern, and part of the eastern regions of Minas Gerais have favourable climates suitable for the cultivation of B. orellana.

https://doi.org/10.1590/1678-4499.2016527 1175 downloads

14.

Aerobic fitness is associated with improved repeated sprints ability of basketball players after six weeks of training during preseason
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Gantois, Petrus

; Aidar, Felipe José

; Dantas, Matheus Peixoto

; Silva, Leandro Medeiros da

; Paes, Pedro Pinheiro

; Santana, Eduardo Estevan

; Dantas, Paulo Moreira da Silva

; Cabral, Breno Guilherme de Araújo Tinôco

Revista Brasileira de Cineantropometria & Desempenho Humano

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Fev 2018, Volume 20 Nº 1 Páginas 114 - 124

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A capacidade de sprints repetidos (CSR) é considerada um importante atributo para o basquetebol, sendo a aptidão aeróbica apontada como fator limitante para a repetição dos sprints. O objetivo do estudo foi verificar se a mudança no VO2PICO se relaciona com a melhoria da CSR após seis semanas de treinamento durante o período preparatório. 12 atletas de basquetebol universitário do sexo masculino com idade entre 18-24 anos participaram do estudo. Os atletas foram submetidos a uma avaliação da composição corporal, teste incremental máximo em esteira e teste de CSR (6x30-m) antes e após seis semanas de treinamento. Para efeito do estudo recorreu-se ao cálculo do delta percentual de mudança. Teste t pareado foi utilizado para verificar as diferenças após o treinamento e a correlação de Pearson e regressão linear simples foram utilizadas para verificar a relação entre o ∆%VO2PICO e ∆%CSR. Observou-se melhorias nos índices CSRPICO (t(1,11)= 2,7; p=0,023); CSRMÉDIA (t(1,11)= 2,8; p=0,019); CSRTOTAL (t(1,11)= 2,6; p=0,028); CSRDEC (t(1,11)= 2,9; p=0,015); e sprints 4 (t(1,11)= 2,4; p=0,037); 5 (t(1,11)= 3,14; p=0,010); e 6 (t(1,11)= 3,65; p=0,004) e VO2PICO (t(1,11)= -5,4; p<0,001); O ∆%VO2PICO se relacionou com o ∆%CSRMÉDIA (r=-0,667; r2= 0,383), ∆%CSRTOTAL (r= -0,673; r2= 0,393), ∆%Sprint 3 (r=-0,669; r2=0,387), ∆%Sprint 4 (r=-0,659; r2=0,371), ∆%Sprint 5 (r=-0,689; r2=0,413), ∆%Sprint 6 (r=-0,678; r2=0,400). É possível concluir que ~39% da melhoria das variáveis associadas com a manutenção de sprints repetidos (CSRMÉDIA; CSRTOTAL; sprints 3,4,5 e 6) dos atletas de basquetebol foi compartilhada pelo aumento de ~7,5% no VO2PICO.

Abstract The repeated sprints ability (RSA) is considered an important attribute for basketball, being aerobic fitness pointed out as limiting factor for repetition of sprints. The aim of the study was to verify if the change in VO2PEAK is related to the improvement of RSA after six weeks of training during preseason. Twelve male college basketball players aged 18-24 participated in the study. Players were submitted to body composition evaluation, maximum incremental treadmill test and RSA test (6x30-m) before and after six weeks of training. For the purpose of the study, the calculation of the change percentage delta was used. Paired t-test was used to verify differences after training and Pearson’s correlation and simple linear regression were used to verify the relationship between ∆%VO2PEAK and ∆%RSA. There were improvements in RSAPEAK (t (1.11) = 2.7, p = 0.023); RSAMEAN (t (1.11)= 2.8, p= 0.019); RSATOTAL (t (1.11)= 2.6, p= 0.028); RSADEC (t (1.11)= 2.9, p= 0.015); and sprints 4 (t (1.11)= 2.4, p= 0.037); 5 (t (1.11)= 3.14, p= 0.010); and 6 (t (1.11)= 3.65,p= 0.004) and VO2PEAK (t (1.11)= -5.4, p <0.001); ∆%VO2PEAK was related to ∆%RSAMEAN (r= -0.667; r2= 0.383), ∆%RSATOTAL (r= -0.673; r2= 0.393), ∆%Sprint 3 (r= -0.669; r2= 0.387), ∆%Sprint 4 (r= -0.659 ; r2 = 0.371), ∆%Sprint 5 (r= -0.689; r2 = 0.413), ∆%Sprint 6 (r= -0.678; r2 = 0.400). It is possible to conclude that ~ 39% of the improvement in variables associated with the maintenance of repeated sprints (RSAMEAN, RSATOTAL, Sprints 3,4,5 and 6) of basketball players was accompanied by an increase of ~ 7.5% in VO2PEAK.

https://doi.org/10.5007/1980-0037.2018v20n1p114 1085 downloads

15.

Agrometeorological models for estimating sweet cassava yield
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Moreto, Victor Brunini

; Aparecido, Lucas Eduardo de Oliveira

; Rolim, Glauco de Souza

; Moraes, José Reinaldo da Silva Cabral de

Pesquisa Agropecuária Tropical

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Jan 2018, Volume 48 Nº 1 Páginas 43 - 51

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O Brasil é o quarto maior produtor mundial de mandioca, tendo as condições climáticas como principais fatores na regulação de sua produção. Objetivou-se desenvolver modelos agrometeorológicos para estimar a produtividade de mandioca doce para o estado de São Paulo, bem como identificar quais variáveis climáticas exercem maior influência sobre a produtividade. Os modelos foram construídos com regressão linear múltipla e classificados pelos seguintes índices estatísticos: menor erro percentual absoluto médio, maior coeficiente de determinação ajustado e significância (p-valor < 0.05). Identificou-se que a temperatura média do ar tem grande influência no rendimento da mandioca durante todo o ciclo, para todas as regiões do estado. O déficit hídrico e o armazenamento de água no solo foram as variáveis mais influentes nos estágios inicial e final. A precisão dos modelos variou em 3,11 %, 6,40 %, 6,77 % e 7,15 %, respectivamente para Registro, Mogi Mirim, Assis e Jaboticabal.

ABSTRACT Brazil is the fourth largest producer of cassava in the world, with climate conditions being the main factor regulating its production. This study aimed to develop agrometeorological models to estimate the sweet cassava yield for the São Paulo state, as well as to identify which climatic variables have more influence on yield. The models were built with multiple linear regression and classified by the following statistical indexes: lower mean absolute percentage error, higher adjusted determination coefficient and significance (p-value < 0.05). It was observed that the mean air temperature has a great influence on the sweet cassava yield during the whole cycle for all regions in the state. Water deficit and soil water storage were the most influential variables at the beginning and final stages. The models accuracy ranged in 3.11 %, 6.40 %, 6.77 % and 7.15 %, respectively for Registro, Mogi Mirim, Assis and Jaboticabal.

https://doi.org/10.1590/1983-40632018v4850451 890 downloads

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