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Bacterial infections after implant surgical procedures are a complication observed in many surgeries to treat bone injuries or diseases. Bacteria can attach to the surface of the implant producing biofilms, and if treatment with antibiotics does not work, further surgery is necessary to remove the infected implant. Among the biomaterials for bone implants, bioceramics based on calcium phosphates (CaPs) such as β-TCP stand out, due to their chemical similarity with bone and high bioresorbability. β-TCP has the characteristic of easily accommodating in its crystalline structure reasonable amounts of doping elements, such as monovalent and trivalent ions, which makes it an efficient transporter of drugs, molecules, and therapeutic ions The objective of this work was the incorporation of bioactive glass (BG 45S5) via sol-gel and silver nanoparticles (Ag-NPs) in β-TCP scaffolds, aiming to confer antimicrobial activity to the scaffolds, without prejudice to biocompatibility. XRD and FT-IR analysis indicated structural changes after the incorporation of BG 45S5 and Ag-NPs in β-TCP scaffolds, and these compounds induced the partial transformation of the β-TCP phase into α-TCP phase and the formation of sodium-calcium silicates and silver silicates. The FT-IR spectra showed characteristic bands of α-TCP after incorporation, in addition to the predominant bands of β-TCP. Biocompatibility after incorporation of BG 45S5 was improved, with a significant increase in cell viability. After the incorporation of Ag-NPs, cell viability was maintained at an acceptable level, no cytotoxic behavior was observed, and the scaffolds showed antibacterial and antifungal activity. The results indicate that BG 45S5 and the Ag-NPs incorporated showed a synergistic behavior, conferring antimicrobial activity to the scaffolds without compromising biocompatibility, showing great potential for applicability in tissue engineering. diseases biofilms implants CaPs (CaPs βTCP β TCP out bioresorbability elements drugs molecules S solgel sol gel AgNPs Ag NPs (Ag-NPs biocompatibility FTIR FT IR 45S αTCP α sodiumcalcium sodium βTCP. TCP. improved AgNPs, NPs, level engineering

https://doi.org/10.1590/1980-5373-mr-2023-0137

Offspring of mothers with bipolar disorder: a systematic review considering personality features
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Bastos, Rodrigo A.

; Campos, Lia S.

; Faria-Schützer, Débora B.

; Brito, Maíra E.

; da Silva, Diego R.

; dos Santos-Junior, Amilton

; Turato, Egberto R.

Brazilian Journal of Psychiatry

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Fev 2022, Volume 44 Nº 1 Páginas 94 - 102

Resumo: En | Texto: En | PDF: En

Objective: To examine personality/temperament features and mental health vulnerability in offspring of mothers with bipolar disorders (BD), including dimensions which may impact psychological characteristics or therapeutic measures. Methods: A systematic review, following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, was conducted to search for original articles that investigated personality/temperament features of offspring of women with BD and emotional factors involved in the mother-child relationship. The electronic search was performed in the PubMed, Web of Science, and PsycINFO databases from February 2010 to February 2017. Results: Ten quantitative studies were included in the analysis: seven from the United States, two from Brazil, and one from Canada. The narrative synthesis was categorized into three dimensions: 1) reliability of instruments for prediction of future psychopathology in offspring; 2) environmental risk factors for offspring; and 3) early interventions. The findings showed impairments in the offspring’s lives, high rates of behavior and temperament problems, and psychiatric disorders. Conclusion: BD is a frequent psychiatric disorder, and the offspring of mothers with this condition are exposed to complex family relationships and psychosocial difficulties. If they are to ensure a good provision of mental health and psychosocial care to this unique population, early interventions must not neglect their contextual specificities. Systematic review registration: PROSPERO CRD-42017039010

https://doi.org/10.1590/1516-4446-2020-1465

Reproduction of saguiru Steindachnerina elegans (Steindachner, 1874) (Pisces: Curimatidae) in the São Francisco River, downstream from a large reservoir in south-eastern Brazil
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CAMPOS FILHO, LÍVIO GIORGIO L. DE

; MARCON, LUCAS

; SANTOS, JOSÉ E. DOS

; SANTIAGO, KLEBER B.

; RIZZO, ELIZETE

; BAZZOLI, NILO

Anais da Academia Brasileira de Ciências

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2022, Volume 94 Nº 2 elocation e20190919

Resumo: En | Texto: En | PDF: En

Abstract The gametogenesis and reproduction of S. elegans from the São Francisco River at Três Marias, Minas Gerais, were analyzed in this study. Steindachrina elegans is a species abundant in the São Francisco River basin and an important fish in the food chain. The size at first gonadal maturation (indicated by the total length of the shortest spermatid male and spawned female) was 10.5 cm and 15.0 cm, respectively. Reproduction occurred more frequently from September to April. This period had high water temperature values. A high frequency of females was observed at the mature and spawned stages and height gonadosomatic index (GSI). Meanwhile, in males, the reproductive peak was from November to February. The long spawning period and the histological characteristics of the spawned ovaries that contained oocytes at different stages of development along with post-ovulatory and atretic oocytes indicates that the spawning of S. elegans is of the partial type.

https://doi.org/10.1590/0001-3765202220190919

Poor Sleep quality and health-related quality of life impact in adolescents with and without chronic immunosuppressive conditions during COVID-19 quarantine
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Helito, Alberto C.

; Lindoso, Livia

; Sieczkowska, Sofia M.

; Astley, Camilla

; Queiroz, Ligia B.

; Rose, Natalia

; Santos, Claudia Renata P.

; Bolzan, Thalis

; Peralta, Rita María I.A.

; Franco, Ruth R.

; Cominato, Louise

; Pereira, Rosa Maria R.

; Tannuri, Uenis

; Campos, Lucia Maria A.

; Lourenço, Benito

; Toma, Ricardo K.

; Medeiros, Karina

; Watanabe, Andréia

; Grangeiro, Patricia Moreno

; Farhat, Sylvia C.

; Casella, Caio B.

; Polanczyk, Guilherme V.

; Gualano, Bruno

; Silva, Clovis A.

; Sallum, Adriana M. E.

; Iraha, Amanda Y.

; Ihara, Bianca P.

; Mazzolani, Bruna C.

; Martinez, Claudia A.

; Strabelli, Claudia A. A.

; Fonseca, Claudia B.

; Lima, Dandara C. C.

; Setoue, Debora N. D.

; Roz, Deborah F. P.

; Smaira, Fabiana I.

; Roschel, Hamilton

; Miyatani, Helena T.

; Marques, Isabela G.

; Oba, Jane

; Ferreira, Juliana C. O.

; Simon, Juliana R.

; Kozu, Katia

; Saccani, Ligia P.

; Martiniano, Lorena V. M.

; Miranda, Luana C. A.

; Silva, Luiz E. V.

; Laurentino, Moisés F.

; Aikawa, Nadia E.

; Sakita, Neusa K.

; Tanigava, Nicolas Y.

; Pereira, Paulo R. A.

; Palmeira, Patrícia

; Angelo, Simone S.

; Lavorato, Sofia S. M.

; Bernardes, Tamires M.

; Franco, Tathiane C.

; Viana, Vivianne S. L.

; Barros, Vera P. M. F. R.

; Zheng, Yingying

Clinics

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2021, Volume 76 elocation e3501

Resumo: En | Texto: En | PDF: En

OBJECTIVE: To assess the possible factors that influence sleep quality in adolescents with and without chronic immunosuppressive conditions quarantined during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: This cross-sectional study included 305 adolescents with chronic immunocompromised conditions and 82 healthy adolescents. Online surveys were completed, which included questions on socio-demographic data and self-rated healthcare routine during COVID-19 quarantine and the following validated questionnaires: the Pittsburgh Sleep Quality Index (PSQI), Pediatric Quality of Life Inventory 4.0 (PedsQL4.0), and Pediatric Outcome Data Collection Instrument (PODCI). RESULTS: The median current age [14 (10-18) vs. 15 (10-18) years, p=0.847] and frequency of female sex (62% vs. 58%, p=0.571) were similar in adolescents with chronic conditions compared with healthy adolescents. The frequency of poor sleep quality was similar in both groups (38% vs. 48%, p=0.118). Logistic regression analysis, including both healthy adolescents and adolescents with chronic conditions (n=387), demonstrated that self-reported increase in screen time (odds ratio [OR] 3.0; 95% confidence interval [CI] 1.3-6.8; p=0.008) and intrafamilial violence report (OR 2.1; 95% CI 1.2-3.5; p=0.008) were independently associated with poor sleep quality in these adolescents. However, the PODCI global function score was associated with a lower OR for poor sleep quality (OR 0.97; 95% CI 0.94-0.99; p=0.001). Further logistic regression, including only adolescents with chronic conditions (n=305), demonstrated that self-reported increase in screen time (OR 3.1; 95% CI 1.4-6.8; p=0.006) and intrafamilial violence report (OR 2.0; 95% CI 1.2-3.4; p=0.011) remained independently associated with poor quality of sleep, whereas a lower PODCI global function score was associated with a lower OR for sleep quality (OR 0.96; 95% CI 0.94-0.98; p<0.001). CONCLUSION: Self-reported increases in screen time and intrafamilial violence report impacted sleep quality in both healthy adolescents and those with chronic conditions. Decreased health-related quality of life was observed in adolescents with poor sleep quality.

https://doi.org/10.6061/clinics/2021/e3501

Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital
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Fink, Thais T.

; Marques, Heloisa H.S.

; Gualano, Bruno

; Lindoso, Livia

; Bain, Vera

; Astley, Camilla

; Martins, Fernanda

; Matheus, Denise

; Matsuo, Olivia M.

; Suguita, Priscila

; Trindade, Vitor

; Paula, Camila S.Y.

; Farhat, Sylvia C.L.

; Palmeira, Patricia

; Leal, Gabriela N.

; Suzuki, Lisa

; Odone Filho, Vicente

; Carneiro-Sampaio, Magda

; Duarte, Alberto José S.

; Antonangelo, Leila

; Batisttella, Linamara R.

; Polanczyk, Guilherme V.

; Pereira, Rosa Maria R.

; Carvalho, Carlos Roberto R.

; Buchpiguel, Carlos A.

; Latronico, Ana Claudia

; Seelaender, Marilia

; Silva, Clovis Artur

; Pereira, Maria Fernanda B.

; Sallum, Adriana M. E.

; Brentani, Alexandra V. M.

; Neto, Álvaro José S.

; Ihara, Amanda

; Santos, Andrea R.

; Canton, Ana Pinheiro M.

; Watanabe, Andreia

; Santos, Angélica C. dos

; Pastorino, Antonio C.

; Franco, Bernadette D. G. M.

; Caruzo, Bruna

; Ceneviva, Carina

; Martins, Carolina C. M. F.

; Prado, Danilo

; Abellan, Deipara M.

; Benatti, Fabiana B.

; Smaria, Fabiana

; Gonçalves, Fernanda T.

; Penteado, Fernando D.

; Castro, Gabriela S. F. de

; Gonçalves, Guilherme S.

; Roschel, Hamilton

; Disi, Ilana R.

; Marques, Isabela G.

; Castro, Inar A.

; Buscatti, Izabel M.

; Faiad, Jaline Z.

; Fiamoncini, Jarlei

; Rodrigues, Joaquim C.

; Carneiro, Jorge D. A.

; Paz, Jose A.

; Ferreira, Juliana C.

; Ferreira, Juliana C. O.

; Silva, Katia R.

; Bastos, Karina L. M.

; Kozu, Katia

; Cristofani, Lilian M.

; Souza, Lucas V. B.

; Campos, Lucia M. A.

; Silva Filho, Luiz Vicente R. F.

; Sapienza, Marcelo T.

; Lima, Marcos S.

; Garanito, Marlene P.

; Santos, Márcia F. A.

; Dorna, Mayra B.

; Aikawa, Nadia E.

; Litvinov, Nadia

; Sakita, Neusa K.

; Gaiolla, Paula V. V.

; Pasqualucci, Paula

; Toma, Ricardo K.

; Correa-Silva, Simone

; Sieczkowska, Sofia M.

; Imamura, Marta

; Forsait, Silvana

; Santos, Vera A.

; Zheng, Yingying

Clinics

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2021, Volume 76 elocation e3511

Resumo: En | Texto: En | PDF: En

OBJECTIVES: To prospectively evaluate demographic, anthropometric and health-related quality of life (HRQoL) in pediatric patients with laboratory-confirmed coronavirus disease 2019 (COVID-19) METHODS: This was a longitudinal observational study of surviving pediatric post-COVID-19 patients (n=53) and pediatric subjects without laboratory-confirmed COVID-19 included as controls (n=52) was performed. RESULTS: The median duration between COVID-19 diagnosis (n=53) and follow-up was 4.4 months (0.8-10.7). Twenty-three of 53 (43%) patients reported at least one persistent symptom at the longitudinal follow-up visit and 12/53 (23%) had long COVID-19, with at least one symptom lasting for >12 weeks. The most frequently reported symptoms at the longitudinal follow-up visit were headache (19%), severe recurrent headache (9%), tiredness (9%), dyspnea (8%), and concentration difficulty (4%). At the longitudinal follow-up visit, the frequencies of anemia (11% versus 0%, p=0.030), lymphopenia (42% versus 18%, p=0.020), C-reactive protein level of >30 mg/L (35% versus 0%, p=0.0001), and D-dimer level of >1000 ng/mL (43% versus 6%, p=0.0004) significantly reduced compared with baseline values. Chest X-ray abnormalities (11% versus 2%, p=0.178) and cardiac alterations on echocardiogram (33% versus 22%, p=0.462) were similar at both visits. Comparison of characteristic data between patients with COVID-19 at the longitudinal follow-up visit and controls showed similar age (p=0.962), proportion of male sex (p=0.907), ethnicity (p=0.566), family minimum monthly wage (p=0.664), body mass index (p=0.601), and pediatric pre-existing chronic conditions (p=1.000). The Pediatric Quality of Live Inventory 4.0 scores, median physical score (69 [0-100] versus 81 [34-100], p=0.012), and school score (60 [15-100] versus 70 [15-95], p=0.028) were significantly lower in pediatric patients with COVID-19 at the longitudinal follow-up visit than in controls. CONCLUSIONS: Pediatric patients with COVID-19 showed a longitudinal impact on HRQoL parameters, particularly in physical/school domains, reinforcing the need for a prospective multidisciplinary approach for these patients. These data highlight the importance of closer monitoring of children and adolescents by the clinical team after COVID-19.

https://doi.org/10.6061/clinics/2021/e3511

Medical Interns and COVID-19: results of national research
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Carrascosa, Maria M. C.

; Campos, Tercio de

; Sampaio, Jéssica E.

; Souza, Rafaella R. F.

; Ribeiro, Vitória L.

; Maia, Maria L. N.

; Gama, Laura C. L.

; Severino, Mariana P.

; Semer, Nathan K.

; Rondon, Otávio

; Silva, Juliana B. M.

; Miyazi, Mariana

; Domingues, Samara R.

; Batalha, Nathália E. S.

; Martins, Delio E.

Revista da Associação Médica Brasileira

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Jun 2020, Volume 66 Nº 6 Páginas 812 - 817

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Avaliar o impacto da Covid-19 durante o internato dos alunos de medicina em escolas públicas e particulares no Brasil, além de estimar a qualidade das medidas tomadas pelas respectivas universidades diante do agravo e da disponibilização de equipamento de proteção individual. MÉTODO Um estudo de análise quantitativa transversal, com caráter descritivo, foi realizado com 317 alunos cursando o internato médico durante o período de 31 de março de 2020 a 12 de abril de 2020. A pesquisa foi realizada por meio de um questionário on-line com 20 perguntas pela ferramenta SurveyMonkey. Os internos do 4o ao 6o ano das faculdades de medicina do País foram incluídos no estudo de forma randômica ao receberem a pesquisa pelo aplicativo WhatsApp. A análise estatística foi realizada por meio do Qui-quadrado, considerando p<0,05 como significante. RESULTADOS Quatro temas principais foram identificados na pesquisa: dados demográficos dos alunos; como as aulas e estágios do curso estão sendo ministrados; a utilização e facilidade de aquisição do equipamento de proteção individual e medos e perspectivas futuras dos estudantes. CONCLUSÕES O estudo mostrou que apesar de metade dos alunos continuarem tendo algum grau de conteúdo e, na maioria, estarem satisfeitos, ainda há muita dificuldade em se obter equipamento de proteção individual, o que impede que os alunos retornem com segurança aos seus campos de estágio, além de causar medo de contaminação e de continuar atendendo os pacientes.

SUMMARY OBJECTIVE Assess the impact of COVID-19 on medical students’ internships in public and private institutions in Brasil, in addition to estimating the quality of the measures taken by their respective Universities in the face of the problem and the availability of personal protective equipment (PPE). METHODS A descriptive cross-sectional quantitative analysis study carried out with 317 students undergoing medical internship from March 31, 2020, to April 12, 2020. The survey was conducted through an online questionnaire using the SurveyMonkey tool with 20 questions. Interns from the fourth to the sixth year of medical schools in the country were randomly included in the study through a survey sent by Whatsapp application. Statistical analysis was performed using the Chi-Square, considering p <0.05 as significant. RESULTS Four main topics were identified in the research: student demographic data; how classes and courses are being taught; the use and ease of access to personal protective equipment and the students’ fears and perspectives for the future. CONCLUSION The study clarified that although half of the students still have some degree of content and, in their majority, they are satisfied, there is still a lot of difficulty in obtaining personal protective equipment, which prevents students from returning safely to their internships.

https://doi.org/10.1590/1806-9282.66.6.812 2594 downloads

Somatic embryogenesis as an alternative for in vitro multiplication of Butia odorata from mature zygotic embryos
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CAMPOS, SAMANTA S. DE

; SCHERWINSKI-PEREIRA, JONNY E.

; BERND, REGINA B.

; FIOR, CLAUDIMAR S.

; SCHWAZ, SERGIO F.

Anais da Academia Brasileira de Ciências

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2020, Volume 92 elocation e20181215

Resumo: En | Texto: En | PDF: En

Abstract Butia odorata is a palm native to southern Brazil and Uruguay, not domesticated, much appreciated for its fruits and economic potential. However, the extractivism and the difficulty of propagation have led to the decline of natural populations. The objective of this work was to prove the possibility of induction of somatic embryogenesis in B. odorata. Mature zygotic embryos were induced in two media, MS and Y3, combined with auxin 2,4-D and picloram in five concentrations (2,4-D: 0, 361.99, 452.49, 542.99 and 633.48 μM/L, picloram: 0, 50, 150, 300 and 450 μM/L). The results promising during induction with the formation of embryogenic calli and somatic embryos, however the regeneration of them was not efficient, this may be due to the occurrence of somatic embryos fused during its development. The roots were formed, but the aerial part remained molten, not completing its development. Auxin picloram and Y3 medium provided the most adequate conditions for calogenesis, formation of embryogenic callus and somatic embryos, with concentrations of 150, 300 and 450 μM/L. This is the first description of somatic embryogenesis in B. odorata that will serve as the basis for future research and adjustments of the methodology proposed here.

https://doi.org/10.1590/0001-3765202020181215 736 downloads

In vitro evaluation of antagonistic microorganisms and fungicides against Colletotrichum theobromicola Delacr, causal agent of anthracnose on soursop (Annona muricata L.) inflorescences
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Cambero-Campos, O. J.

; Rios-Velasco, C.

; Cruz-Crespo, E.

; Cambero-Ayón, C. B.

; Luna-Esquivel, G.

Revista bio ciencias

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2019, Volume 6 elocation e678

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The objective of this study was to evaluate the in vitro antagonism of six strains of microorganisms on Colletotrichum theobromicola Delacr, the causal agent of anthracnose in soursop (Annona muricata L.) inflorescences in Nayarit, Mexico. Three strains of Trichoderma (T. asperellum, T. harzianum and T. longibrachiatum), three strains of Streptomyces [Streptomyces sp. (A7), S. tubercidicus (A19), and S. viridochromogenes (A27)] and seven commercial fungicides Maxtrobyn® (azoxystrobin SC), ExCitrus® (Citric extract + quercetin), Canelys® (Cinnamomum zeylanicum extract), Hidrocu® PH (Copper hydroxide), Pull75WG® (cuprous oxide), Score® 250 EC (Difenoconazole) and Switch® 62.5 WG (cyprodinil + fludioxonil) were used. The fungicides doses were: D1 (half of the recommended dose), D2 (recommended dose), and D3 (recommended dose plus half of it), according to the doses recommended by the manufacturer. The six antagonists showed more than 80 % of radial growth inhibition, the genus Streptomyces was the most efficient inhibiting up to a 90 % the growth of C. theobromicola. Strain A27 completely inhibited the fungi (100 %), followed by strains A19 (96.18 %) and A7 (90.4 %). SCORE® 250 EC, Canelys® and Hidrocu® PH fungicides showed a 100 % in vitro inhibition of C. theobromicola with the three doses analyzed. The results of this study demonstrate the potential of Streptomyces spp. strains and commercial fungicides for the control of C. theobromicola, which can be further used in the integrated management for controlling anthracnose in soursop.

Resumen El objetivo del presente estudio consistió en evaluar el antagonismo in vitro de seis cepas de microorganismos sobre Colletotrichum theobromicola Delacr, causante de antracnosis en inflorescencias de Annona muricata L. en Nayarit, México. Se usaron tres cepas de Trichoderma (T. asperellum, T. harzianum y T. longibrachiatum), tres de Streptomyces [Streptomyces sp. (A7); S. tubercidicus (A19), y S. viridochromogenes (A27)] y siete fungicidas comerciales Maxtrobyn® (azoxistrobin SC), ExCitrus® (Extracto cítrico + quercetina), Canelys® (Extracto de Cinnamomum zeylanicum), Hidrocu® PH (Hidróxido de cobre), Pull75WG® (óxido cuproso), Score® 250 EC (Difenoconazol) y Switch® 62.5 WG (cyprodinil + fludioxonil). Las dosis evaluadas de los fungicidas fueron: D1 (mitad de la dosis recomendada), D2 (dosis recomendada), y D3 (dosis recomendada más la mitad de ésta), partiendo de las dosis recomendadas por el fabricante. Los seis antagonistas mostraron un alto porcentaje de inhibición de crecimiento radial, superior a 80 %, destacando el género Streptomyces al inhibir hasta en un 90 % el crecimiento de C. theobromicola. La cepa A27 lo inhibió por completo (100 %), seguido por las cepas A19 (96.18 %) y A7 (90.4 %). Los fungicidas SCORE® 250 EC, Canelys® e Hidrocu® PH mostraron un 100 % de inhibición in vitro de C. theobromicola con las tres dosis probadas. Los resultados de este estudio demuestran el potencial de cepas de Streptomyces spp. y de fungicidas comerciales para el control de C. theobromicola, los cuales son candidatos para ser usados en el manejo integrado de antracnosis en guanábana.

https://doi.org/10.15741/revbio.06.e678 358 downloads

A solar mid-infrared telescope
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Mendoza-Torres, J. E.

; Palacios-Fonseca, J. S.

; Velázquez-de-la-Rosa, M.

; Rodríguez-Montero, P.

; De-Roa-Campoy, A.

; Valadez-Campos, E.

; Arias-Estrada, M. O.

; Peña-Saint-Martín, J.

; Rodríguez-Pedroza, B.

; Gómez-Arista, I.

; Juárez-Gama, M.

; Gottschalk, K.

; Medina-Carrillo, I. C.

Revista mexicana de astronomía y astrofísica

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2019, Volume 55 Nº 1 Páginas 11 - 16

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT: We developed a mid infrared (MIR) solar telescope, centered at 10µm. Various optical layouts were analyzed based on computer simulations and a Ritchey-Chretien 6-inches telescope was selected with a plate scale of 2.5′′/mm using a pyroelectric 4 × 16 pixels detector. The angular resolution is 36′′/pixel with a field of view of 9.6′ × 2.4′. Two germanium filters are used, one at the aperture of the telescope and another near its focal plane. The detector was characterized with a laboratory black-body. The count values follow a linear relation with the black-body temperature. The control systems for both the telescope and the detector were developed. Proper mechanical supports were designed for the filters, detector and electronics. The system has been integrated and a user interface was developed. Preliminary observations have been made giving a signal-to-noise ratio of ≈ 1000.

RESUMEN: Desarrollamos un telescopio solar en el infrarrojo medio (MIR), centrado en 10µm. Estudiamos varios diseños ópticos, con base en simulaciones de computadora y seleccionamos un telescopio Ritchey-Chretien de 6 pulgadas con escala de placa de 2.5′′/mm, con un detector piroeléctrico de 4 × 16 pixeles. La resolución angular es de 36′′/pixel con un campo de visión de 9.6′ × 2.4′. Se usan dos filtros de germanio, uno en la apertura del telescopio y otro cerca del plano focal. El detector se caracterizó con un cuerpo negro de laboratorio. Los valores, en cuentas, siguen una relación lineal con la temperatura del cuerpo negro. Se hicieron los sistemas de control del telescopio y del detector. Se diseñaron soportes mecánicos para los filtros, el detector y la electrónica. El sistema se integró y se hizo una interfaz para el usuario. Las observaciones preliminares muestran que se obtiene una relación señal a ruido de ≈ 1000.

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10.

Estudo da incorporação de pó de concha de marisco em massa de porcelanato
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Fulgêncio, E. B. G. A.

; Medeiros, F. K. de

; Cartaxo, J. M.

; Dutra, R. P. S.

; Macedo, D. A.

; Campos, L. F. A.

Cerâmica

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Set 2018, Volume 64 Nº 371 Páginas 381 - 387

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo A pesca de mariscos é uma das atividades comerciais mais importantes da comunidade pesqueira do município de Cabedelo (Paraíba, Brasil). O processo de beneficiamento, após a extração do molusco, gera elevada quantidade de conchas, cujo descarte, em volume considerável, provoca assoreamento de áreas extensas e consequente desequilíbrio ambiental. Na busca do aproveitamento desses resíduos (conchas de mariscos) e visando a redução dos problemas ambientais causados, esse trabalho teve como objetivo o estudo da incorporação de pó de conchas de mariscos em massa de porcelanato. Composições cerâmicas foram formuladas a partir de uma massa de porcelanato industrial e pó de concha de marisco ou CaCO3 comercial variando entre 0 e 7% em massa. Corpos de prova preparados por prensagem uniaxial tiveram suas propriedades tecnológicas avaliadas em função da temperatura de sinterização. Os resultados indicaram que o uso de até 7% em massa de pó de concha mantém as propriedades tecnológicas dentro dos padrões exigidos pela ABNT (Brasil) para a classificação como cerâmicas de revestimento do grupo BIa.

Abstract The fishing of shellfish is one of the most important commercial activities of the fishing community of the municipality of Cabedelo (Paraíba, Brazil). The step of processing, after the extraction of the mollusk, generates a large amount of shells, whose discharge, in considerable volume, causes silting of large areas and consequent environmental imbalance. In the search for the use of these residues (mollusk shells) and aiming at reducing the environmental problems caused, this work had the aim of studying the incorporation of mollusk shell powder in the mass of porcelain tile. Ceramic compositions were formulated from an industrial standard mass and mollusk shell powder or commercial CaCO3 ranging from 0 to 7% by weight. Samples prepared by uniaxial pressing had their technological properties evaluated as a function of the sintering temperature. The results indicated that the use of up to 7 wt% of the mollusk shell powder maintains the technological properties within the standards required by the ABNT (Brazil) for classification as BIa type porcelain tiles.

https://doi.org/10.1590/0366-69132018643712368 1686 downloads

11.

Diffuse alveolar hemorrhage in childhoodonset systemic lupus erythematosus: a severe disease flare with serious outcome
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Blay, Gabriela

; Rodrigues, Joaquim C.

; Ferreira, Juliana C. O.

; Leal, Gabriela N.

; Gormezano, Natali W.

; Novak, Glaucia V.

; Pereira, Rosa M. R.

; Terreri, Maria T.

; Magalhães, Claudia S.

; Molinari, Beatriz C.

; Sakamoto, Ana P.

; Aikawa, Nadia E.

; Campos, Lucia M. A.

; Fernandes, Taciana A. P.

; Clemente, Gleice

; Peracchi, Octavio A. B.

; Bugni, Vanessa

; Marini, Roberto

; Sacchetti, Silvana B.

; Carvalho, Luciana M.

; Fraga, Melissa M.

; Castro, Tânia C. M.

; Ramos, Valéria C.

; Bonfá, Eloisa

; Silva, Clovis A.

Advances in Rheumatology

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2018, Volume 58 elocation 39

Resumo: En | Texto: En | PDF: En

Abstract Objective: To evaluate prevalence, clinical manifestations, laboratory abnormalities and treatment in a multicenter cohort study including 847 childhood-onset systemic lupus erythematosus (cSLE) patients with and without diffuse alveolar hemorrhage (DAH), as well as concomitant parameters of severity. Methods: DAH was defined as the presence of at least three respiratory symptoms/signs associated with diffuse interstitial/alveolar infiltrates on chest x-ray or high-resolution computer tomography and sudden drop in hemoglobin levels. Statistical analysis was performed using Bonferroni correction (p < 0.0022). Results: DAH was observed in 19/847 (2.2%) cSLE patients. Cough/dyspnea/tachycardia/hypoxemia occurred in all cSLE patients with DAH. Concomitant parameters of severity observed were: mechanical ventilation in 14/19 (74%), hemoptysis 12/19 (63%), macrophage activation syndrome 2/19 (10%) and death 9/19 (47%). Further analysis of cSLE patients at DAH diagnosis compared to 76 cSLE control patients without DAH with same disease duration [3 (1–151) vs. 4 (1–151) months, p = 0.335], showed higher frequencies of constitutional involvement (74% vs. 10%, p < 0.0001), serositis (63% vs. 6%, p < 0.0001) and sepsis (53% vs. 9%, p < 0.0001) in the DAH group. The median of disease activity score(SLEDAI-2 K) was significantly higher in cSLE patients with DAH [18 (5–40) vs. 6 (0–44), p < 0.0001]. The frequencies of thrombocytopenia (53% vs. 12%, p < 0.0001), intravenous methylprednisolone (95% vs. 16%, p < 0.0001) and intravenous cyclophosphamide (47% vs. 8%, p < 0.0001) were also significantly higher in DAH patients. Conclusions: This was the first study to demonstrate that DAH, although not a disease activity score descriptor, occurred in the context of significant moderate/severe cSLE flare. Importantly, we identified that this condition was associated with serious disease flare complicated by sepsis with high mortality rate.

https://doi.org/10.1186/s42358-018-0038-4 467 downloads

12.

Effect of Bauhinia holophylla treatment in Streptozotocin-induced diabetic rats
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PINHEIRO, MARCELO S.

; RODRIGUES, LUHARA S.

; S. NETO, LEILA

; MORAES-SOUZA, RAFAIANNE Q.

; SOARES, THAIGRA S.

; AMÉRICO, MADILEINE F.

; CAMPOS, KLEBER E.

; DAMASCENO, DÉBORA C.

; VOLPATO, GUSTAVO T.

Anais da Academia Brasileira de Ciências

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Mar 2017, Volume 89 Nº 1 Páginas 263 - 272

Resumo: En | Texto: En | PDF: En

ABSTRACT Bauhinia holophylla, commonly known as “cow’s hoof”, is widely used in Brazilian folk medicine for the diabetes treatment. Therefore, the aim of this study was at evaluating the aqueous extract effect of Bauhinia holophylla leaves treatment on the streptozotocin-induced diabetic rats. Diabetes was induced by Streptozotocin (40 mg/Kg) in female Wistar rats. Oral administration of aqueous extract of Bauhinia holophylla leaves was given to non-diabetic and diabetic rats at a dose of 400 mg/kg during 21 days. On day 17 of treatment, the Oral Glucose Tolerance Test was performed to determine the area under the curve. At the end of the treatment, the animals were anesthetized and blood was collected for serum biochemical parameters analysis. After treatment with Bauhinia holophylla extract, non-diabetic and diabetic rats presented no glycemic changes. On the other hand, the plant treatment decreased body weight and increased ALT and AST activities. In conclusion, the treatment with aqueous extract of B. holophylla leaves given to diabetic rats presented no hypoglycemic effect in nondiabetic animals and no antidiabetic effect in diabetic animals with the doses studied. In addition, the diabetic animals treated with the B. holophylla extract showed inconvenient effects and its indiscriminate consumption requires particular carefulness.

https://doi.org/10.1590/0001-3765201720160050 2848 downloads

13.

Annularins I and J: New Metabolites Isolated from Endophytic Fungus Exserohilum rostratum
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Pinheiro, Eduardo A. A.

; Borges, Fabio C.

; Pina, Jeferson R. S.

; Ferreira, Leila R. S.

; Cordeiro, Jorgeffson S.

; Carvalho, Josiwander M.

; Feitosa, André O.

; Campos, Francinete R.

; Barison, Andersson

; Souza, Afonso D. L.

; Marinho, Patrícia S. B.

; Marinho, Andrey M. R.

Journal of the Brazilian Chemical Society

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Ago 2016, Volume 27 Nº 8 Páginas 1432 - 1436

Resumo: En | Texto: En | PDF: En

The paper describes the isolation of ergosterol peroxide, monocerin, annularin I and annularin J compounds of Exserohilum rostratum biomass extracts. Compounds were isolated by silica gel column chromatography in polarity gradient and the structures were determined by nuclear magnetic resonance (NMR) and mass spectrometry (MS) methods. Monocerin, annularin I and annularin J compounds were tested against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis bacteria and showed moderate activity. Annularin I and annularin J compounds are new natural products.

https://doi.org/10.5935/0103-5053.20160140 931 downloads

14.

Medições e modelagem da pegada hídrica da cana-de-açúcar cultivada no Estado da Paraíba
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Silva, Vicente de P. R. da

; Albuquerque, Monik F. de

; Araújo, Lincoln E. de

; Campos, João H. B. da C.

; Garcêz, Silvia L. A.

; Almeida, Rafaela S. R.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Jun 2015, Volume 19 Nº 6 Páginas 521 - 526

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O conceito de pegada hídrica tem tido bastante interesse atualmente haja vista que a água doce é um recurso global utilizado em todos os ramos de atividades e pode ser fundamental para ajudar a compreender como as atividades e os produtos estão relacionados com a escassez de água. O objetivo deste estudo é comparar as medições da pegada hídrica da cana-de-açúcar derivadas pelo método tradicional utilizado na sua estimativa usando o balanço hídrico completo no solo em condições de campo. O experimento de campo foi realizado na Fazenda Capim II, localizada no litoral do estado da Paraíba, Brasil, no período de outubro de 2009 a agosto de 2010 com cana-de-açúcar, cultivar RB 92 579. Os resultados evidenciaram que os valores da pegada hídrica verde e cinza diminuem à medida que há acréscimo na lâmina de irrigação. Inversamente, os valores da pegada hídrica azul aumentam sempre que há incremento na lâmina de irrigação. A pegada hídrica da cana-de-açúcar obtida com base no modelo CROPWAT, superestima os valores da pegada hídrica verde e azul e subestima os valores da pegada hídrica cinza, obtidos com base no balanço hídrico do solo.

ABSTRACT The water footprint concept has gained interest because the freshwater is a global resource utilized in all activities and can be fundamental in helping to understand how activities and products are related to water scarcity. The purpose of this study is to compare the sugarcane water footprint measurements derived by the traditional method used for its estimation and using the complete water balance in the soil under field conditions. The field experiment was carried out at the Capim II farm located in the coastal area of state of Paraiba, Brazil, during the period from October 2009 to August 2010 with sugarcane. The results indicated that the green and gray water footprint values decrease as there is an increase in irrigation depth. Inversely, the blue water footprint values increase as there is an increase in irrigation depth. The sugarcane water footprint based on the CROPWAT model overestimates green and blue water footprint values and underestimates the gray water footprint values obtained from the soil water balance.

https://doi.org/10.1590/1807-1929/agriambi.v19n6p521-526 2592 downloads

15.

Efeito da adição de Nb2O5 na sinterização de Al2O3-Y2O3
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Cabral, R. F.

; Louro, L. H. L.

; Campos, J. B.

; Lima, E. S.

Matéria (Rio de Janeiro)

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Jun 2014, Volume 19 Nº 2 Páginas 125 - 131

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

A utilização de Y3Al5O12 (YAG - "Ittrium Aluminum Garnet" - Garnet de Alumínio e Ítrio), como reforço em matriz de Al2O3 tem sido estudada desde a década de 1990. As propriedades mecânicas e de resistência à fluência obtidas pelo compóstito Al2O3-YAG têm revelado um grande potencial para seu emprego a temperaturas elevadas por períodos longos de tempo, permitindo a sua utilização na indústria aeroespacial e energética. O objetivo desta pesquisa foi investigar a sinterização do Al2O3 com Y2O3 explorando a presença de fase líquida com o uso do Nb2O5 como aditivo de sinterização para a obtenção do compósito bifásico Al2O3-YAG. No presente estudo, foram produzidas as seguintes composições, utilizando moagem de alta energia: Al2O3 com 4% em peso de Nb2O5 como aditivo de sinterização, Al2O3-YAG também com 4% em peso de Nb2O5 e Al2O3-YAG sem aditivo. Os corpos verdes foram prensados a 70 MPa e sinterizados a 1400 e 1450ºC por 2, 3 e 4 h. Os materiais foram caracterizados por microscopia eletrônica de varredura (MEV) e avaliação de porosidade. O compósito Al2O3-YAG sinterizado a 1400 e 1450ºC apresentou uma porosidade de 40 e 35%, respectivamente, indicando que ainda são necessários mais ajustes em seu processamento.

The use of Y3Al5O12 (YAG - Itrium Aluminum Garnet) as reinforcement element in Al2O3 matrix has been studied since the 1990s. The outstanding mechanical properties and creep resistance obtained by the composite Al2O3-YAG have revealed a great potential for its use at high temperatures for long periods, allowing its use in aerospace and energy. The objective of this research has been to investigate the sintering of Al2O3-Y2O3 system, exploring the presence of a liquid phase from using Nb2O5 as a sintering additive for obtaining the Al2O3-YAG biphasic composite. In this study, the following compositions have been produced using high energy milling: Al2O3 with 4wt% Nb2O5 as sintering additive, Al2O3-YAG also with 4 wt% of Nb2O5, and Al2O3-YAG without additive. The green bodies have been pressed at 70 MPa and sintered at 1400 and 1450ºC for 2, 3 and 4 h. The materials have been characterized by scanning electron microscopy (SEM) and their porosity was measured. The composite Al2O3-YAG sintered at 1400 and 1450ºC has showed a porosity of 40 and 35%, respectively, indicating that there are still needs of adjustments on its processing.

https://doi.org/10.1590/S1517-70762014000200007 1154 downloads

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