ABSTRACT Introduction: Chikungunya chronic joint disease causes debilitating arthralgia, significantly impacting the quality of life of affected individuals. Methods: In this study, patients underwent clinical follow-ups, joint biopsies, and pre-biopsy and 24 months post-biopsy serum dosage of cytokines. Results: All participants were female and had pain in 12 joints on average, with 41.17% exhibiting moderate disease activity. Histopathological analysis revealed collagen deposition. Indirect immunofluorescence detected the CHIKV glycoprotein E1 antigen, and an increase in cytokines. Conclusions: Persistent inflammation and ineffective antiviral immune responses leading to antigen persistence may contribute to chronic CHIKV arthritis.

RESUMO Thielaviopsis paradoxa é fungo do solo, patógeno amplamente distribuído em todo o mundo e capaz de infectar uma ampla gama de hospedeiros. Em palma de óleo é o agente etiológico da podridão basal, uma importante doença que pode causar sérios prejuízos devido à sua severidade e à rápida dispersão do patógeno. O trabalho teve como objetivo avaliar a patogenicidade e caracterizar um isolado de Thielaviopsis sp. em palma de óleo. O isolado de Thielaviopsis sp. foi obtido do estipe de plantas de palma de óleo, com aparentes sintomas de podridão. A patogenicidade foi avaliada em duas cultivares de palma de óleo, o híbrido interespecífico Manicoré e o híbrido intraespecífico Tenera. As mudas foram inoculadas por suspensão de conídios na concentração de 1x107 conídios por mililitro e discos de micélios, com e sem ferimentos na ráquis de folhas. O isolado foi cultivado em meio de cultura BDA para a caracterização morfológica. A análise filogenética foi realizada com base em comparação de sequências das regiões EF-1? e ITS com sequências disponíveis no GenBank-NCBI e analisadas no Mega 6.0. O isolado foi patogênico nas duas cultivares da palma de óleo em mudas previamente feridas, causando sintomas de podridão de coloração marrom, com formação de um halo amarelado na ráquis. Com o progresso da doença, as folhas apresentaram coloração amarelo progredindo para seca até a quebra da ráquis. O isolado de Thielaviopsis sp. apresentou crescimento rápido com velocidade de crescimento micelial de 50,76 mm dia-1 e com dois dias ocupou totalmente a placa de Petri de 90 mm. A colônia, de coloração inicialmente branca, tornou-se negra com a esporulação e produção de dois tipos de conídios: os endoconídios e aleuroconídios. Após as análises filogenéticas, foi possível comprovar a espécie Thielaviopsis ethacetica como agente etiológico da podridão basal da palma de óleo, distinguindo-a da espécie T. paradoxa.

ABSTRACT Thielaviopsis paradoxa is a soilborne fungal pathogen widely distributed worldwide and capable of infecting a wide range of hosts. In oil palm, it is the etiological agent of basal rot, an important disease that can cause serious damage due to its severity and the rapid dispersion of the pathogen. This study evaluated the pathogenicity and characterized an isolate of Thielaviopsis sp. in oil palm. The isolate was obtained from the stem of an oil palm plant with apparent rot symptoms. Pathogenicity was evaluated in two oil palm cultivars, the interspecific hybrid Manicoré and the intraspecific hybrid Tenera. Seedlings were inoculated by conidial suspension at 1x107 conidia per milliliter e mycelial disks, with and without injuries in the leaf rachis. The isolate was grown in PDA culture medium for morphological characterization. Phylogenetic analysis was performed based on comparison of sequences from the EF-1? and ITS regions with sequences available from GenBank-NCBI and analyzed in Mega 6.0. The isolate was pathogenic to the two oil palm cultivars in previously injured seedlings, causing symptoms of brown rot and formation of a yellowish halo in the rachis. As the disease progressed, the leaves showed yellow coloration and dried, resulting in broken rachis. The isolate of Thielaviopsis sp. showed rapid growth with mycelial growth rate of 50.76 mm day-1, covering the 90-mm Petri plate within two days. The colony, initially white, became black with sporulation and produced two types of conidia: endoconidia and aleuroconidia. After phylogenetic analyses, the species Thielaviopsis ethacetica could be proven as the etiological agent of the dry basal rot of oil palm and could be distinguished from T. paradoxa.

ABSTRACT OBJECTIVE: To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil. METHODS: A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response. Qualitative detection of IgM and IgG antibodies was performed in a fully-automated Elecsys® Anti-SARS-CoV-2 electrochemiluminescence immunoassay on the Cobas® e601 analyzer (Roche Diagnostics). RESULTS: In total, 3,156 individuals were interviewed. Seroprevalence of total antibodies against SARS-CoV-2 was 40.4% (95%CI 35.6-45.3). Population adherence to non-pharmaceutical interventions was higher at the beginning of the pandemic than in the last month. SARS-CoV-2 infection rates were significantly lower among mask wearers and among those who maintained social and physical distancing in the last month compared to their counterparts. Among the infected, 26.0% were asymptomatic. The infection fatality rate (IFR) was 0.14%, higher for men and older adults. The IFR based on excess deaths was 0.28%. The ratio of estimated infections to reported cases was 22.2. CONCLUSIONS: To the best of our knowledge, the seroprevalence of SARS-CoV-2 estimated in this population-based survey is one of the highest reported. The local herd immunity threshold may have been reached or might be reached soon.

ABSTRACT OBJECTIVE: To estimate the seroprevalence of SARS-CoV-2 in the state of Maranhão, Brazil. METHODS: A population-based household survey was performed, from July 27, 2020 to August 8, 2020. The estimates considered clustering, stratification and non-response. Qualitative detection of IgM and IgG antibodies was performed in a fully-automated Elecsys® Anti-SARS-CoV-2 electrochemiluminescence immunoassay on the Cobas® e601 analyzer (Roche Diagnostics). RESULTS: In total, 3,156 individuals were interviewed. Seroprevalence of total antibodies against SARS-CoV-2 was 40.4% (95%CI 35.6-45.3). Population adherence to non-pharmaceutical interventions was higher at the beginning of the pandemic than in the last month. SARS-CoV-2 infection rates were significantly lower among mask wearers and among those who maintained social and physical distancing in the last month compared to their counterparts. Among the infected, 26.0% were asymptomatic. The infection fatality rate (IFR) was 0.14%, higher for men and older adults. The IFR based on excess deaths was 0.28%. The ratio of estimated infections to reported cases was 22.2. CONCLUSIONS: To the best of our knowledge, the seroprevalence of SARS-CoV-2 estimated in this population-based survey is one of the highest reported. The local herd immunity threshold may have been reached or might be reached soon.

RESUMO Objetivo: o duodenal switch é um procedimento disabsortivo complexo, associado aos melhores resultados de perda de peso e controle metabólico. A cirurgia em etapas, com gastrectomia vertical como primeiro passo, é uma opção para reduzir complicações em pacientes superobesos. No entanto, alguns problemas persistem, como fígados grandes, que dificultam a abordagem cirúrgica, e complicações, como fístulas graves. A bipartição do trânsito intestinal é um modelo modificado e simplificado de desvio biliopancreático que complementa a gastrectomia vertical. É semelhante ao duodenal switch com menores complexidade e consequências nutricionais. Este estudo avaliou a viabilidade e a segurança da bipartição de trânsito isolada como o procedimento inicial para tratar a superobesidade. Métodos: foram incluídos 41 pacientes superobesos, com IMC médio de 54,5±3,5kg/m2. Uma bipartição de trânsito isolada laparoscópica foi realizada como o primeiro procedimento em uma nova abordagem em duas etapas. Perda de peso e complicações foram analisadas durante um ano de acompanhamento. Resultados: todos os procedimentos foram completados por laparoscopia. Após seis meses, a perda média de excesso de peso percentual foi de 28%, permanecendo estável até o final do estudo. Não houve dificuldades intraoperatórias. Metade dos pacientes apresentou diarreia precoce e três tiveram úlceras marginais. Não houve complicações cirúrgicas maiores ou mortes. Conclusão: a bipartição de trânsito isolada laparoscópica é uma nova opção para uma abordagem em estágios na superobesidade, que pode permitir um segundo procedimento mais seguro após a perda de peso ao longo de seis meses. Pode ser útil, particularmente, para pacientes com obesidade grave.

ABSTRACT Objective: biliopancreatic diversion with duodenal switch is a complex, malabsorptive procedure, associated with improved weight loss and metabolic control. Staged surgery with sleeve gastrectomy as the first stage is an option for reducing complications in superobese patients. However, some problems persist: large livers can hamper the surgical approach and complications such as leaks can be severe. Intestinal transit bipartition is a modified and simplified model of biliopancreatic diversion that complements sleeve gastrectomy. It is similar to the duodenal switch, but with less complexity and fewer nutritional consequences. This study assessed the feasibility and safety of isolated transit bipartition as the initial procedure in a two-step surgery to treat superobesity. Methods: this prospective study included 41 superobese patients, with mean BMI 54.5±3.5kg/m2. We performed a laparoscopic isolated transit bipartition as the first procedure in a new staged approach. We analyzed weight loss and complications during one year of follow-up. Results: we completed all the procedures by laparoscopy. After six months, the mean percent excess weight loss was 28%, remaining stable until the end of the study. There were no intraoperative difficulties. Half of the patients experienced early diarrhea, and three had marginal ulcers. There were no major surgical complications or deaths. Conclusion: isolated laparoscopic transit bipartition is a new option for a staged approach in superobesity, which can provide a safer second procedure after effective weight loss over six months. It may be useful particularly in the management of patients with severe obesity.

Abstract Introduction: bariatric surgery is a favorable option for the treatment of obesity, resulting in long-term weight loss. Objectives: to analyze whether feeding behavior, evaluated by caloric intake, dietary preferences and tolerance, can be considered as a determinant factor for weight loss in obese patients submitted to Roux-en-Y gastric bypass (RYGB). Methods: cross-sectional study of 105 patients with at least two years post-RYGB surgery with a preoperative body mass index (BMI) of ≥ 35 kg/m². Caloric intake was evaluated by 24-hour dietary recall and 3-day dietary intake record; dietary habits, by a qualitative dietary frequency questionnaire; and food tolerance, with a validated questionnaire. Multiple logistic regression was used for statistical analysis. Results: the majority of the 105 participants were female (84%). The mean age was 43.3 ± 11.4 years in the success group (n = 64) and 43.4 ± 10.7 years in the failure group (n = 41). Preoperative BMI was not associated with the outcome. Mean caloric intake did not show significant differences between groups: 24 hours recall, p = 0.27; 3-day record, p = 0.95. The frequency of weekly consumption of desserts was twice as high in the success group. Only two patients in the success group presented daily vomiting. Conclusion: the factors that determine the failure of weight loss have not yet been fully elucidated. Caloric intake was not a determining factor of failure, and insufficient weight loss was more prevalent in patients who ceased to lose weight earlier.

Resumen Introducción: la cirugía bariátrica es una opción favorable para el tratamiento de la obesidad, resultando a largo plazo en pérdida de peso. Objetivos: analizar si el comportamiento alimentario, evaluado por la ingesta calórica, las preferencias y las tolerancias alimentarias, puede ser considerado un factor determinante de los resultados de pérdida de peso en pacientes obesos sometidos a bypass gástrico en Y de Roux (BPGYR). Métodos: se realizó un estudio de cohorte retrospectivo con 105 pacientes sometidos a cirugía de BPGYR, con índice de masa corporal (IMC) preoperatorio ≥ 35 kg/m² y, como mínimo, dos años de postoperatorio. La ingesta calórica fue evaluada por el recordatorio alimentario de 24 horas y el registro alimentario de tres días. Para la evaluación de los hábitos alimentarios se empleó un cuestionario cualitativo de frecuencia alimentaria y para la tolerancia alimentaria, un cuestionario validado. Resultados: la mayoría de los participantes eran del sexo femenino (84%). La edad promedio fue de 43,30 ± 11,39 años en el grupo éxito y de 43,39 ± 10,73 años en el grupo sin éxito. El IMC preoperatorio no presentó influencia sobre el resultado final. El promedio de ingesta calórica no mostró diferencia significativa entre los grupos estudiados (R 24 h, p = 0,27; registro del diario alimentario, p = 0,95). La frecuencia del consumo semanal de dulces fue dos veces mayor en el grupo éxito. Apenas dos pacientes del grupo éxito presentaban vómitos diarios. Conclusión: los factores que determinan la falta de éxito en la pérdida de peso aún no están bien esclarecidos. La ingesta calórica no fue un factor determinante para no obtener éxito y la pérdida de peso insuficiente fue más prevalente en los pacientes que dejaron de perder peso más temprano.

RESUMO Racional: Diabete mellito tipo 2 apresenta alta taxa de remissão em longo prazo após derivação gástrica em Y-de-Roux (DGYR), mas poucos estudos analisaram pacientes com IMC <35 kg/m2. Objetivo: Comparar o controle glicêmico de pacientes após DGYR entre IMC 30-35 kg/m2 (grupo intervenção ou GI) e >35 kg/m2 (grupo controle ou GC) e avaliar a perda de peso, comorbidades e morbidade cirúrgica. Método: Sessenta e seis pacientes diabéticos (30 no grupo GI e 36 no GC) foram submetidos à DGYR. Dados foram coletados anualmente após a operação e analisados com equações de estimativa generalizada. Resultados: A média de seguimento foi 4,3 anos. Não houve diferença estatística entre os grupos usando critérios de remissão completa da American Diabetes Association (OR 2,214, 95%IC 0,800-5,637, p=0,13). Houve diferença significativa entre os grupos usando critérios de remissão parcial da American Diabetes Association (p=0,002), favorecendo o grupo GC (OR 6,392, 95%IC 1,922-21,260). O grupo com IMC maior também teve menores níveis de HbA1c (-0,77%, 95%IC -1,26 a -0,29, p=0,002). Não houve diferença significativa na remissão de hipertensão, dislipidemia e morbidade cirúrgica, enquanto o peso foi melhor controlado no grupo GI. Conclusão: Nenhuma diferença foi encontrada na remissão completa do diabete, embora maior remissão parcial e menores níveis de hemoglobina glicada no grupo com IMC >35 kg/m2 sugiram melhor resposta entre diabéticos mais obesos com DGYR. Além disso, ambos os grupos tiveram importantes modificações metabólicas às custas da baixa morbidade.

ABSTRACT Background: Type 2 diabetes mellitus has a high long-term remission rate after laparoscopic Roux-en-Y gastric bypass (LRYGB), but few studies have analyzed patients with BMI<35 kg/m2. Aim: To compare glycemic control after LRYGB between BMI 30-35 kg/m2 (intervention group or IG) and >35 kg/m2 patients (control group or CG) and to evaluate weight loss, comorbidities and surgical morbidity. Methods: Sixty-six diabetic patients (30 in IG group and 36 in CG group) were submitted to LRYGB. Data collected annually after surgery were analyzed with generalized estimating equations. Results: Average follow-up was 4.3 years. There was no statistical difference between groups using complete remission American Diabetes Association criteria (OR 2.214, 95%CI 0.800-5.637, p=0.13). There was significant difference between groups using partial remission American Diabetes Association criteria (p=0.002), favouring the CG group (OR 6.392, 95%CI 1.922-21.260). The higher BMI group also had lower HbA1c levels (-0.77%, 95%CI -1.26 to -0.29, p=0.002). There were no significant differences in remission of hypertension, dyslipidemia and surgical morbidity, while weight was better controlled in the IG group. Conclusion: No differences were found in diabetes complete remission, although greater partial remission and the lower levels of glycated hemoglobin in the BMI >35 kg/m2 group suggest a better response among more obese diabetic patients with LRYGB. In addition, both groups had important metabolic modifications at the expense of low morbidity.

With the growth of soybean production in Latin America, a new relationship between agriculture and region is being built. As a result, certain areas marked by different historical and social contexts have gone through similar processes to those of landscape transformation; as if they were part of a same region. The aim of this paper is to present evidence to define the soybean production system from the study of recent conditions which highlight the progress of this activity in the states of Maranhão, Piauí, Tocantins and Bahía, in Brazil, and the provinces of Chaco and Formosa, in Argentina. This analysis was based on literature concerning these regions, secondary data and information about soybean production in both countries. Conclusions point to the fact that in the period marked by globalization, the studied areas can be considered as part of the same expansion dynamics of territories intended for soybean growth.

Con el aumento de la producción de soja en América Latina, se está construyendo una nueva relación entre agricultura y las regiones productoras. Por consecuencia de esto, determinados lugares, discontinuos y marcados por contextos históricos y sociales distintos pasan por procesos análogos con respecto a la transformación de su paisaje; como si fuesen parte de una misma región. En el siguiente artículo se ofrecerán evidencias que definen este sistema productivo sojero partiendo del estudio de las condiciones recientes que marcan el avance de esta actividad en los estados de Maranhão, Piauí, Tocantins y Bahía en Brasil, así como, en las provincias de Chaco y Formosa en la Argentina. Para la investigación de este estudio se tomaron textos que han trabajado con estos temas en estas regiones, así como datos secundarios e información sobre la producción de soja en ambos países. Las conclusiones indican que, en el período marcado por la globalización, las áreas estudiadas pueden ser comprendidas como partes integrantes de una misma dinámica de expansión de territorios funcionales a la soja.

No presente trabalho foram avaliados a atividade antinociceptiva e o perfil fitoquímico dos extratos aquosos e metanólico produzidos com a casca do caule de Abarema cochliacarpos, uma espécie de Mata Atlântica com diversas indicações populares. Todos os extratos apresentaram atividade analgésica quando avaliados pelo teste das contorções abdominais induzidas pelo ácido acético via intraperitonial, apresentando respostas superiores às drogas usadas como referência, bem como no modelo da dor induzida por capsaicina. A avaliação fitoquímica demonstrou a presença de saponinas, catequinas, taninos, fenóis e antraquinonas.

In this study, we investigated the analgesic activity of crude aqueous and methanol extracts obtained from Abarema cochliacarpos bark in mice, and analyzed its phytochemical profile. All the extracts exhibited analgesic properties against the writhing test in mice, but the aqueous and methanol extracts were more active, and more potent than two known analgesic and anti-inflammatory drugs used as reference. They were also active against the capsaicin-model, but inactive when evaluated in the hot-plate test. Phytochemical studies revealed the presence of saponins, catechins, tannins, phenols and anthraquinones.

O presente artigo estuda a origem, o desenvolvimento e a decadência, no ambiente urbano paulistano, de um tipo de construção denominado chalé. Fruto do Romantismo do século XIX, e muito popular no último terço do oitocentismo, o chalé assumiu alto valor simbólico - embora de significado ambíguo -, por estar ligado tanto à noção de uma idealizada vida campestre, quanto à de modernidade técnica, que então se introduzia em São Paulo. Popularizou-se em razão da facilidade de importação de material de construção industrializado e expandiu-se durante a onda construtiva que atingiu a capital paulista a partir do ano de 1875. Em fins do Império, foi objeto de medidas restritivas municipais por ter sido considerada desregrada sua proliferação no espaço urbano da cidade. E, a partir do começo do século XX, a transformação do gosto, as reformas urbanísticas então encetadas no Centro paulistano (1902-1914) e o desejo de construir um novo cenário urbano segundo o sistema de valores e os interesses das camadas hegemônicas contribuíram para o seu gradativo desaparecimento.

This article studies the origins, flourishment and decadence of a certain style of building, known as swiss cottages or chalets, in the urban environment of Sao Paulo. Its source is found in 19th century romanticism and in the last quarter of the eighteen hundreds this kind of construction was very popular. At this time it had taken on a high symbolic value - although of an ambiguous nature - for it was both intimately associated to an idealization of country life and to technological modernity, which was then being ushered in the city of Sao Paulo. It became very popular on account of the availability of industrialized construction material for importation and it expanded during a construction boom that attained the city of Sao Paulo, after 1875. On the downfall of Brazilian monarchy, it gradually disappeared, as it became the object of restrictive measures from the local county, which considered its proliferation unruly. From the beginning of the XXth century, there was a change in public taste and urban reforms were implemented in downtown Sao Paulo (1902 to 1914), which was followed by a desire for a new urban scene, more in touch with the system of values and interests of hegemonic sectors of the local political elite.

RACIONAL: A execução de bypass gástrico laparoscópico em hospital universitário público tem sido difícil devido ao elevado custo dos grampeadores cirúrgicos que prejudica o treinamento de médicos residentes e tem motivado a busca por técnicas alternativas, de baixo custo, mantendo a eficácia. OBJETIVO: Apresentar a viabilidade de um método com menor uso de suturas mecânicas. MÉTODOS: Foram operados 63 pacientes em 2 hospitais universitários, sendo 12 homens e 51 mulheres (81%), com média de 33,5 anos de idade e IMC médio de 43. Aplicou-se a seguinte padronização técnica: Secção da alça com bisturi elétrico a 50 cm do ângulo duodeno-jejunal, anastomose término-lateral, passagem da alça retrocólica e retrogástrica, confecção da parede lateral da bolsa gástrica com 1 carga azul de 45 e outra de 60 mm após a secção horizontal com bisturi elétrico, sutura do estômago excluso e anastomose gastrojejunal. As anastomoses foram manuais e contínuas com fio absorvível. RESULTADOS: O tempo operatório médio foi de 5,5 horas. As complicações precoces foram: fístula no ângulo de esôfago-gástrico (1,6%), estenose (1,6%) e fístula na anastomose gastrojejunal (1,6%) e torção da anastomose intestinal (1,6%). A estenose foi tratada por dilatação endoscópica e as outras complicações através de 3 re-operações (2 laparoscópicas e 1 laparotômica). O tempo de internação variou de 2 a 20 dias, com média de 4 dias, não havendo óbito. CONCLUSÃO: Este método é viável e com baixo custo operacional; todavia, é complexo e requer habilidade principalmente em suturas laparoscópicas.

BACKGROUND: To perform laparoscopic gastric bypass in public university hospital has been difficult due to the high cost of the surgical staplers. This fact induced to look for different technical options, with low cost, maintaining the efficacy. AIM: To present the viability of a new method with the use of a low number of stapler devices. METHODS: Sixty three patients were operated in two university hospitals, 12 men and 51 women (81%), with mean age of 33.5y and average BMI of 43. The surgical technique used followed this sequence: loop section with electrical scalpel 50 cm of the duodenojejunal angle; termino-lateral anastomosis; retrogastric-retrocolic passage of the Roux limb; construction of the lateral wall of the pouch using 1 blue load of 45 and other of 60 mm after horizontal section with electrical scalpel; suture of the excluded stomach and gastrojejunal anastomosis. The anastomoses were hand-sewn made and a single-layer continuous absorble suture was performed. RESULTS: The average surgical time was 5.5 hours. The early complications were: fistula in the esophago-gastric angle (1.6%), stenosis (1.6%); fistula in the gastro-jejunal anastomosis (1.6%); obstruction of the intestinal anastomosis (1.6%). The stenosis was treated by endoscopic dilation. The remaining complications, with 3 re-operations (2 with laparoscopic and 1 with laparotomic approaches). The length of hospital stay was in average 4 days. CONCLUSION: This method is viable with low cost; however, it is complex and requires ability mainly in laparoscopic handsewn sutures.

Tomadas entre os anos de 1862 e 1863, as primeiras fotos paulistanas de autoria de Militão Augusto de Azevedo são sempre evocadas por documentarem a vetustez, a precariedade e a letargia da cidade de São Paulo dos meados do século XIX. Nossa interpretação, no entanto, baseada na leitura de fontes primárias da época, propõe um sentido substancialmente oposto a esse. Entre os anos de 1850 e 1860, a arquitetura e os espaços urbanos de São Paulo já apresentavam significativas modernizações, que aparecem nas fotografias de Militão de Azevedo, hoje pertencentes ao acervo do Museu Paulista e também da Divisão de Iconografia e Museus, do Departamento do Patrimônio Histórico paulistano.

The first photographs of São Paulo, taken by Militão Augusto de Azevedo between 1862 and 1863, are always cited as documentary evidence of the city's backwardness, deterioration, and lethargy in the mid 19th century. However, our view is that things were quite different, based on a reading of prime sources dating back to that period. In fact, the architecture and urban spaces of São Paulo already showed clear signs of modernization between the years 1850 and 1860, as depicted in Azevedo's photographs, which belong to the collection of Paulista Museum and also of the Iconography and Museums Division of the São Paulo Heritage Department.

O presente artigo dedica-se a recuperar a memória de antigos palacetes erguidos nas proximidades da Estação da Luz a partir do início da segunda metade do século XIX. Foi por essa época que a região se tornou o primeiro bairro residencial de elite da cidade de São Paulo, concentrando palacetes que expressaram elaborações locais de vertentes do Neoclassismo e do Ecletismo arquitetônicos. Pretende-se, assim, abordar os processos de interpretação que caracterizaram essa produção arquitetônica.

The present article is dedicated to recover the memory of the old mansions built in the region of Luz Railway Station, from the beginning of the second half of the 19th Century onwards. It was around that time that the region became São Paulo elite's first residential neighbourhood, concentrating mansions that expressed the local elaborations of architectural Neo-classicism and Eclecticism. One intends to approach the interpretation processes that characterised such architectural production.