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Abstract Objective: To assess the predictive value of selected growth phenotypes for neonatal morbidity and mortality in preterm infants < 30 weeks and to compare them with INTERGROWTH-21st (IG21). Methods: Retrospective analysis of data from the Brazilian Neonatal Research Network (BNRN) database for very low birth weight (VLBW) at 20 public tertiary-care university hospitals. Outcome: the composite neonatal morbidity and mortality (CNMM) consisted of in-hospital death, oxygen use at 36 weeks, intraventricular hemorrhage grade 3 or 4, and Bell stage 2 or 3 necrotizing enterocolitis. Selected growth phenotypes: small-for-gestational-age (SGA) defined as being < 3rd (SGA3) or 10th (SGA10) percentiles of BW, and large-for-gestational-age (LGA) as being > 97th percentile of BW. Stunting as being < 3rd percentile of the length and wasting as being < 3rd percentile of BMI. Single and multiple log-binomial regression models were fitted to estimate the relative risks of CNMM, comparing them to IG21. Results: 4,072 infants were included. The adjusted relative risks of CNMM associated with selected growth phenotypes were (BNRN/IG21): 1.45 (0.92–2.31)/1.60 (1.27–2.02) for SGA; 0.90 (0.55–1.47)/1.05 (0.55–1.99) for LGA; 1.65 (1.08–2.51)/1.58 (1.28–1.96) for stunting; and 1.48 (1.02–2.17) for wasting. Agreement between the two references was variable. The growth phenotypes had good specificity (>95%) and positive predictive value (70-90%), with poor sensitivity and low negative predictive value. Conclusion: The BNRN phenotypes at birth differed markedly from the IG21 standard and showed poor accuracy in predicting adverse neonatal outcomes.

https://doi.org/10.1016/j.jped.2022.07.007

Translation and validation of a questionnaire on the impact of strabismus on the quality of life of patients
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Margotto, Fernanda Serrão

; Minguini, Nilza

; Batalha, Carolina Peres

; de Melo, Mayra Neves

; Alves, Monica

; de Carvalho, Keila Monteiro

Revista Brasileira de Oftalmologia

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2023, Volume 82 elocation e0007

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To translate and validate the Adult Strabismus Quality of Life Questionnaire into Brazilian Portuguese. Methods: A cross-sectional study for linguistic and cross-cultural validation of the Adult Strabismus Quality of Life Questionnaire in order to assess the quality of life in patients with strabismus. We have followed previous published guidelines on translation process to ensure the equivalence between the original and translated versions. The final version was applied in a pilot study to evaluate concordance and its reliability and reproducibility as a tool to be used in future studies. Results: The translation and counter translation processes of the Adult Strabismus Quality of Life Questionnaire were conducted according to preestablished protocols. The analysis of the results obtained in the test–retest application of the questionnaire in a sample of 30 participants revealed a correlation coefficient of 0.67, which was deemed satisfactory for the validation process of this tool. Conclusion: The Adult Strabismus Quality of Life Questionnaire was translated and validated according to preestablished protocols. The referred questionnaire has been used in studies worldwide, so this process will enable its application to better understand the impact of strabismus in patients’ quality of life in the Brazilian population.

RESUMO Objetivo: Traduzir e validar o questionário Adult Strabismus Quality of Life Questionnaire (AS-20) para o português brasileiro. Métodos: Estudo transversal para validação linguística e transcultural do questionário Adult Strabismus Quality of Life Questionnaire (AS-20) para avaliação da qualidade de vida em pacientes com estrabismo. Foram seguidas as diretrizes já publicadas sobre o processo de tradução, para garantir a equivalência entre as versões original e traduzida. A versão final foi aplicada em um estudo-piloto para avaliar a concordância e sua confiabilidade e reprodutibilidade, como ferramenta a ser utilizada em estudos futuros. Resultados: Os processos de tradução e contratradução do questionário Adult Strabismus Quality of Life Questionnaire (AS-20) foram realizados de acordo com protocolos preestabelecidos. A análise dos resultados obtidos na aplicação teste-reteste do questionário em uma amostra de 30 participantes revelou coeficiente de correlação de 0,67, que foi considerado satisfatório para o processo de validação desse instrumento. Conclusão: O questionário Adult Strabismus Quality of Life Questionnaire (AS-20) foi traduzido e validado de acordo com protocolos preestabelecidos. O referido questionário vem sendo utilizado em estudos ao redor do mundo e, portanto, esse processo possibilitará sua aplicação para melhor compreensão do impacto do estrabismo na qualidade de vida dos pacientes da população brasileira.

https://doi.org/10.37039/1982.8551.20230007

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Resumo: En | Texto: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Working memory and arithmetic impairments in children with FMR1 premutation and gray zone alleles
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Martins, Aline Aparecida Silva

; Paiva, Giulia Moreira

; Matosinho, Carolina Guimarães Ramos

; Coser, Elisângela Monteiro

; Fonseca, Pablo Augusto de Souza

; Haase, Vitor Geraldi

; Carvalho, Maria Raquel Santos

Dementia & Neuropsychologia

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Mar 2022, Volume 16 Nº 1 Páginas 105 - 114

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO. Mutações expansivas no gene FMR1 têm sido associadas a diferentes fenótipos. Mutações completas estão associadas a deficiência intelectual e transtorno do espectro do autismo; pré-mutações, com dificuldades de aprendizagem de matemática e comprometimentos de memória de trabalho. Na zona cinzenta o desenvolvimento neuropsicológico ainda não foi descrito. Objetivos: Descrever a frequência de alelos pré-mutados e zona cinzenta em uma amostra escolar que representa amplo espectro de variação do desempenho em Matemática e detalhar o desempenho escolar e cognitivo em crianças identificadas com alelos pré-mutados ou zona cinzenta. Métodos: Aqui, descrevemos um estudo de duas fases. Na primeira fase, 2.195 crianças em idade escolar foram selecionadas para desempenho em Matemática. Na segunda fase, 378 crianças com inteligência normal foram avaliadas neuropsicologicamente e, em seguida, por genotipagem FMR1. Resultados: Tiveram desempenho abaixo do percentil 25 em Matemática (grupo DM) 121 crianças (61 meninas), e tiveram desempenho acima do percentil 25 (grupo controle) 257 crianças (146 meninas). Quatro alunos apresentaram alelos expandidos, sendo uma pré-mutação e três alelos da zona cinza. A menina com a pré-mutação e um menino com o alelo da zona cinza apresentaram prejuízos na memória de trabalho e desempenho aritmético abaixo do percentil 6, compatíveis com o diagnóstico de discalculia do desenvolvimento. As dificuldades dessas crianças não foram associadas à imprecisão de representações não simbólicas de números ou deficiências de alfabetização. A discalculia nessas crianças parece estar associada principalmente a deficiências da memória de trabalho. Conclusões: Em conclusão, expansões na zona cinzenta do FMR1 podem contribuir para a discalculia em crianças saudáveis com inteligência normal.

ABSTRACT. Expansive mutations in familial mental retardation 1 (FMR1) gene have been associated with different phenotypes. Full mutations are associated with intellectual disability and autism spectrum disorder; premutations are associated with math learning difficulties and working memory impairments. In gray zone, neuropsychological development has not yet been described. Objectives: This study aimed to describe the frequency of FMR1 premutation and gray zone alleles in a school population sample representing a broad spectrum of variation in math achievement and detail school achievement and cognitive performance in the children identified with FMR1 premutation or gray zone alleles. Methods: We described a two-phase study. In the first phase, 2,195 school-age children were screened for math achievement. In the second phase, 378 children with normal intelligence were neuropsychologically assessed and genotyped for FMR1. Of these, 121 children (61 girls) performed below percentile 25 in mathematics (MD group) and 257 children (146 girls) performed above percentile 25 (control group). Results: Four pupils presented expanded alleles, one premutation and three gray zone alleles. The girl with the premutation and one boy with a gray zone allele presented impairments in working memory and arithmetic performance below percentile 6, compatible with the diagnosis of developmental dyscalculia. These children’s difficulties were not associated with inaccuracy of nonsymbolic number representations or literacy impairments. Dyscalculia in these children seems to be associated mainly with working memory impairments. Conclusions: FMR1 expansions in the gray zone may contribute to dyscalculia in otherwise healthy and normally intelligent children.

https://doi.org/10.1590/1980-5764-dn-2021-0035

Severe acute respiratory syndrome coronavirus 2 infection among healthcare workers in a tertiary public hospital in Curitiba, Brazil
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Spalanzani, Regiane Nogueira

; Genelhoud, Gustavo

; Raboni, Sonia Mara

; Almeida, Sergio Monteiro de

; Pereira, Luciane Aparecida

; Rotta, Indianara

; Cavalli, Barbara Maria

; Moreira, Francielli Brusco

; Dino, Carolina Lumi Tanaka

; Takahashi, Gislene Reche de Almeida

; Cognialli, Regielly Caroline Raimundo

; Spiri, Beatriz Sanada

; Bochnia-Bueno, Lucas

; Oliveira, Jaqueline Carvalho de

; Adamoski, Douglas

; Gradia, Daniela Fiori

; Bonatto, Ana Cláudia

; Wassem, Roseli

; Alves, Juliana Mazini

; Padilha, Raquel da Silva

; Brasil, Vitor Jorge Woytuski

; Almeida, Bernardo Montesanti Machado de

; Nogueira, Meri Bordignon

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 elocation e0265-2021

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: We aimed to describe the clinical characteristics of coronavirus disease 2019 (COVID-19) among healthcare workers (HCWs) in Curitiba, Brazil. METHODS: Upper respiratory samples from 1077 HCWs were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using reverse transcription polymerase chain reaction from June 16, 2020 to December 9, 2020. RESULTS: Overall, 32.7% of HCWs were infected. The positivity rates in symptomatic and asymptomatic HCWs were 39.2% and 15.9%, respectively. Hospital departments categorized as high-risk for exposure had the highest number of infected HCWs. CONCLUSIONS: Early diagnosis and isolation of infected HCWs remain key in controlling SARS-CoV-2 transmission because HCWs in close contact with COVID-19 patients are more likely to be infected than those who are not.

https://doi.org/10.1590/0037-8682-0265-2021

Centro de operações de emergência na COVID-19: a experiência do município do Rio de Janeiro
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Oliveira e Cruz, Débora Medeiros de

; Carvalho, Luciana Freire de

; Costa, Carolina Monteiro da

; Aguilar, Gislani Mateus Oliveira

; Saraceni, Valéria

; Cruz, Oswaldo Gonçalves

; Durovni, Betina

; Soranz, Daniel Ricardo

; Oliveira Garcia, Márcio Henrique de

Revista Panamericana de Salud Pública

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2022, Volume 46 elocation e9

Resumo: En Pt Es | Texto: En Pt Es | PDF: En | PDF: Pt | PDF: Es

ABSTRACT The present report describes the implementation of an emergency operations center to coordinate the response to the COVID-19 pandemic in the municipality of Rio de Janeiro, Brazil. Following the public health emergency management framework proposed by the World Health Organization (WHO), this temporary center (COE COVID-19 RIO) started operating in January 2021. The report is organized along five themes: legal framework; structure, planning, and procedures; institutional articulation; health information for decision-making; and risk communication. Major advances obtained with the initiative include improvements in governance for the management of COVID-19, increase in the synergy among sectors and institutions, improved information sharing in relation to COVID-19 prevention and control measures, innovation in epidemiologic analyses, and gains in transparency and decision-making opportunities. In conclusion, even if conceived at an advanced stage of the pandemic in the municipality of Rio de Janeiro, the COE COVID-19 RIO has played a relevant role in shaping the city’s responses to the pandemic. Also, despite its temporary character, the experience will leave a lasting legacy for the management of future public health emergencies in the municipality of Rio de Janeiro.

RESUMO O presente artigo descreve a experiência de implantação de um centro de operações de emergência (COE) para coordenação da resposta à pandemia de COVID-19 no município do Rio de Janeiro, Brasil. Seguindo o modelo de gestão de emergências em saúde pública preconizado pela Organização Mundial da Saúde (OMS), este centro de caráter temporário (COE COVID-19 RIO) foi ativado em janeiro de 2021. O relato foi estruturado com base em cinco eixos temáticos: arcabouço legal; estrutura, planos e procedimentos; articulações institucionais; informações em saúde para apoio decisório; e comunicação de risco. Entre os avanços importantes relacionados ao estabelecimento desta iniciativa, destacaram-se ganhos em governança para a organização do enfrentamento à COVID-19, aumento da sinergia entre setores e instituições, maior compartilhamento de informações em relação às medidas de prevenção e controle da doença, inovação nas análises epidemiológicas e ganhos na transparência e oportunidade na tomada de decisões. Concluiu-se que, mesmo sendo concebido em estágio avançado da pandemia na cidade, o COE COVID-19 RIO teve papel relevante na estruturação da resposta. Ainda, apesar do caráter temporário do COE, a experiência mostrou-se como importante legado para a condução de futuras emergências em saúde pública no município do Rio de Janeiro.

RESUMEN En el presente artículo se describe la experiencia al establecerse un centro de operaciones de emergencia (COE) para coordinar la respuesta a la pandemia de COVID-19 en el municipio de Rio de Janeiro (Brasil). Siguiendo el modelo de gestión de emergencias de salud pública promovido por la Organización Mundial de la Salud (OMS), este centro temporal se activó en enero del 2021. El informe se estructuró con base en cinco ejes temáticos: marco legal; estructura, planes y procedimientos; articulaciones institucionales; información en materia de salud para sustentar las decisiones; y comunicación sobre riesgos. Entre los principales avances relacionados con esta iniciativa cabe destacar los adelantos en cuanto a la gobernanza para organizar la forma de enfrentar la COVID-19, el aumento de la sinergia entre los sectores y las instituciones correspondientes, un mayor intercambio de información sobre las medidas de prevención y control de la enfermedad, innovación en los análisis epidemiológicos, mayor transparencia en la toma de decisiones y decisiones tomadas de manera más oportuna. Se llegó a la conclusión de que este COE, a pesar de que había sido establecido en una fase avanzada de la pandemia en la ciudad, tuvo un papel importante en la estructuración de la respuesta. Sin embargo, a pesar de su carácter temporal, la experiencia demostró ser un importante legado para enfrentar futuras emergencias de salud pública en el municipio de Rio de Janeiro.

https://doi.org/10.26633/rpsp.2022.9

SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
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Pereira, Maria Fernanda Bádue

; Suguita, Priscila

; Litvinov, Nadia

; Farhat, Sylvia Costa Lima

; Paula, Camila Sanson Yoshino de

; Lázari, Carolina dos Santos

; Bedê, Pedro Vale

; Framil, Juliana Valeria de Souza

; Bueno, Catarina

; Branas, Priscila Cristina Abduch Adas

; Guimarães, Irina Monteiro da Costa

; Leite, Marcia Marques

; Navega, Ana Carolina Barsaglini

; Nanbu, Danilo Yamamoto

; Schvartsman, Claudio

; Pinho, João Renato Rebello

; Silva, Clovis Artur Almeida

; Marques, Heloisa Helena de Sousa

; Eisencraft, Adriana Pasmanik

; Rossi Jr, Alfio

; Delgado, Artur Figueiredo

; Leal, Gabriela Nunes

; Gibelli, Maria Augusta Cicaroni

; Palmeira, Patricia

; Sakita, Neusa Keico

; Santos, Emilly Henrique dos

; Rocha, Mussya Cisotto

; Kanunfre, Kelly Aparecida

; Okay, Thelma Suely

; Carneiro-Sampaio, Magda

; Carvalho, Werther Brunow de

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volume 64 elocation e34

Resumo: En | Texto: En | PDF: En

ABSTRACT This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.

https://doi.org/10.1590/s1678-9946202264034

Management of Acute Type A Aortic Dissection at a Public Cardiac Center in the Northeast Region of Brazil
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Bezerra, Pablo Cesar Lustosa Barros

; Lima, Ricardo de Carvalho

; Salerno, Pedro Rafael de

; Martins, Antonio Cavalcanti de Albuquerque

; Lustosa, Geovanna Menezes de Medeiros

; Perazzo, Alvaro Monteiro

; Salerno, Juliana Vieira de Oliveira

; Salerno, Carolina Vieira de Oliveira

; Salerno, Pedro Rafael Vieira de Oliveira

Brazilian Journal of Cardiovascular Surgery

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Abr 2021, Volume 36 Nº 2 Páginas 150 - 157

Resumo: En | Texto: En | PDF: En

Abstract Introduction: Aortic diseases are among the most serious cardiovascular diseases; the overall mortality rate due to diseases such as aneurysms and aortic dissections has been estimated at 2.78 per 100,000 persons in 2010, with a higher mortality rate in men than women. Our objective was to evaluate the epidemiological profile of patients with acute type A aortic dissection at a cardiology referral center. Methods: A retrospective cross-sectional study was performed at a public cardiac center with 24 patients hospitalized from 1/1/2016 to 12/31/2017 with a confirmed diagnosis of acute type A aortic dissection. Results: Twenty (83.3%) out of 24 patients underwent surgery and four (16.7%) did not undergo surgery. Among those who underwent surgery, 10 (50%) died and 10 (50%) were discharged, and all non-operated patients died (P=0.114) (Fisher's exact test). The male gender predominated (n=19, 79.2%), 86.7% (n=13) of the patients presented body mass index > 25 kg/m2, chest pain was found in 91.7% (n=22), and renal failure was present in 45.8% (n=11) of the cases. Hypertension predominated in 91.7% (n=22) and the main exam was aortic angiotomography in 79.2% (n=19) of the cases. Conclusion: The study presented a small sample size, making it impossible to associate the factors, although the service was considered a high-volume referral center. It is possible that the delay in arriving at the service and the accomplishment of invasive imaging with the use of contrast agents have aggravated the patients’ condition and have been decisive for the increase in lethality, which requires further studies.

https://doi.org/10.21470/1678-9741-2020-0169 138 downloads

Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: infecções que causam cervicite
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Miranda, Angélica Espinosa

; Silveira, Mariângela Freitas da

; Pinto, Valdir Monteiro

; Alves, Geralda Carolina

; Carvalho, Newton Sergio de

Epidemiologia e Serviços de Saúde

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2021, Volume 30 Nº spe1 elocation e2020587

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo As infecções que causam cervicite são um dos temas que compõem o Protocolo Clínico e Diretrizes Terapêuticas para Atenção Integral às Pessoas com Infecções Sexualmente Transmissíveis, publicado pelo Ministério da Saúde do Brasil em 2020. Tal documento foi elaborado com base em evidências científicas e validado em discussões com especialistas. Este artigo apresenta aspectos epidemiológicos e clínicos das infecções que causam cervicite, bem como recomendações sobre a triagem, diagnóstico e tratamento das pessoas acometidas e suas parcerias sexuais. Além disso, discutem-se estratégias para as ações de vigilância, prevenção e controle desses agravos para os profissionais de saúde e gestores envolvidos no manejo programático e operacional das infecções sexualmente transmissíveis. A ampliação do acesso aos testes para diagnóstico e o tratamento precoce são cruciais para o controle da disseminação dos patógenos causadores de cervicite.

Abstract Infections that cause cervicitis are a topic presented in the “Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections”, published by the Brazilian Ministry of Health in 2020. The document was developed based on scientific evidence and validated in discussions with experts. This article presents epidemiological and clinical aspects of infections that cause cervicitis, as well as recommendations on screening, diagnosis and treatment of affected people and their sexual partnerships. In addition, it discusses strategies for surveillance, prevention and control of these infections for health professionals and health service managers involved in the programmatic and operational management of sexually transmitted infections. Expanding access to diagnostic tests and early treatment are crucial for controlling the spread of pathogens that cause cevicitis.

Resumen Las infecciones que causan cervicitis son uno de los temas que integran el Protocolo Clínico y Directrices Terapéuticas para la Atención Integral a las Personas con Infecciones de Transmisión Sexual, publicado por el Ministerio de Salud de Brasil en 2020. El documento fue desarrollado en base a evidencia científica y validado en discusiones con expertos. Este artículo presenta aspectos epidemiológicos y clínicos de las infecciones que causan cervicitis, así como recomendaciones sobre el cribado, diagnóstico y tratamiento de las personas afectadas y sus parejas sexuales. Además, se discuten estrategias de vigilancia, prevención y control de estas enfermedades para los profesionales y gestores de salud involucrados en el manejo programático y operativo de las infecciones de transmisión sexual. Ampliar el acceso a las pruebas de diagnóstico y a un tratamiento precoz es crucial para controlar la propagación de los agentes patógenos que causan cervicitis.

https://doi.org/10.1590/s1679-4974202100008.esp1 1389 downloads

10.

Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: infecções que causam cervicite
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Miranda, Angélica Espinosa

; Silveira, Mariângela Freitas da

; Pinto, Valdir Monteiro

; Alves, Geralda Carolina

; Carvalho, Newton Sergio de

Epidemiologia e Serviços de Saúde

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2021, Volume 30 Nº spe1 elocation e2020587

Resumo: Pt Es En | Texto: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/s1679-4974202100008.esp1

11.

Brazilian Protocol for Sexually Transmitted Infections, 2020: infections that cause cervicitis
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Miranda, Angélica Espinosa

; Silveira, Mariângela Freitas da

; Pinto, Valdir Monteiro

; Alves, Geralda Carolina

; Carvalho, Newton Sergio de

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 Supl. 1 elocation e2020587

Resumo: En | Texto: En | PDF: En

Abstract Infections that cause cervicitis are a topic presented in the "Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections", published by the Brazilian Ministry of Health in 2020. The document was developed based on scientific evidence and validated in discussions with experts. This article presents epidemiological and clinical aspects of infections that cause cervicitis and recommendations on screening, diagnosis, and treatment of affected people and their sexual partnerships. Also, it discusses strategies for surveillance, prevention, and control of these infections for health professionals and health service managers involved in the programmatic and operational management of sexually transmitted infections. Expanding access to diagnostic tests and early treatment are crucial for controlling the spread of pathogens that cause cervicitis.

https://doi.org/10.1590/0037-8682-587-2020 369 downloads

12.

Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital
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Marques, Heloisa Helena de Sousa

; Pereira, Maria Fernanda Badue

; Santos, Angélica Carreira dos

; Fink, Thais Toledo

; Paula, Camila Sanson Yoshino de

; Litvinov, Nadia

; Schvartsman, Claudio

; Delgado, Artur Figueiredo

; Gibelli, Maria Augusta Bento Cicaroni

; Carvalho, Werther Brunow de

; Odone Filho, Vicente

; Tannuri, Uenis

; Carneiro-Sampaio, Magda

; Grisi, Sandra

; Duarte, Alberto José da Silva

; Antonangelo, Leila

; Francisco, Rossana Pucineli Vieira

; Okay, Thelma Suely

; Batisttella, Linamara Rizzo

; Carvalho, Carlos Roberto Ribeiro de

; Brentani, Alexandra Valéria Maria

; Silva, Clovis Artur

; Eisencraft, Adriana Pasmanik

; Rossi Junior, Alfio

; Fante, Alice Lima

; Cora, Aline Pivetta

; Reis, Amelia Gorete A. de Costa

; Ferrer, Ana Paula Scoleze

; Andrade, Anarella Penha Meirelles de

; Watanabe, Andreia

; Gonçalves, Angelina Maria Freire

; Waetge, Aurora Rosaria Pagliara

; Silva, Camila Altenfelder

; Ceneviva, Carina

; Lazari, Carolina dos Santos

; Abellan, Deipara Monteiro

; Santos, Emilly Henrique dos

; Sabino, Ester Cerdeira

; Bianchini, Fabíola Roberta Marim

; Alcantara, Flávio Ferraz de Paes

; Ramos, Gabriel Frizzo

; Leal, Gabriela Nunes

; Rodriguez, Isadora Souza

; Pinho, João Renato Rebello

; Carneiro, Jorge David Avaizoglou

; Paz, Jose Albino

; Ferreira, Juliana Carvalho

; Ferranti, Juliana Ferreira

; Ferreira, Juliana de Oliveira Achili

; Framil, Juliana Valéria de Souza

; Silva, Katia Regina da

; Kanunfre, Kelly Aparecida

; Bastos, Karina Lucio de Medeiros

; Galleti, Karine Vusberg

; Cristofani, Lilian Maria

; Suzuki, Lisa

; Campos, Lucia Maria Arruda

; Perondi, Maria Beatriz de Moliterno

; Diniz, Maria de Fatima Rodrigues

; Fonseca, Maria Fernanda Mota

; Cordon, Mariana Nutti de Almeida

; Pissolato, Mariana

; Peres, Marina Silva

; Garanito, Marlene Pereira

; Imamura, Marta

; Dorna, Mayra de Barros

; Luglio, Michele

; Rocha, Mussya Cisotto

; Aikawa, Nadia Emi

; Degaspare, Natalia Viu

; Sakita, Neusa Keico

; Udsen, Nicole Lee

; Scudeller, Paula Gobi

; Gaiolla, Paula Vieira de Vincenzi

; Severini, Rafael da Silva Giannasi

; Rodrigues, Regina Maria

; Toma, Ricardo Katsuya

; Paula, Ricardo Iunis Citrangulo de

; Palmeira, Patricia

; Forsait, Silvana

; Farhat, Sylvia Costa Lima

; Sakano, Tânia Miyuki Shimoda

; Koch, Vera Hermina Kalika

; Cobello Junior, Vilson

Clinics

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2021, Volume 76 elocation e3488

Resumo: En | Texto: En | PDF: En

OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results. RESULTS: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children (MIS-C) (OR 11.261; 95% CI 1.189-106. 581; p=0.035). CONCLUSIONS: Half of the laboratory-confirmed COVID-19 cases occurred in adolescents. Individuals belonging to this age group had an acute systemic involvement of SARS-CoV-2 infection. Pediatric SARS and MIS-C were the most important factors associated with the mortality rate in pediatric chronic conditions with COVID-19.

https://doi.org/10.6061/clinics/2021/e3488

13.

Nexos de exclusão e desafios de sustentabilidade e saúde em uma periferia urbana no Brasil
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Giatti, Leandro Luiz

; Urbinatti, Alberto Matenhauer

; Carvalho, Carolina Monteiro de

; Bedran-Martins, Ana Maria

; Santos, Izabela Penha de Oliveira

; Honda, Simone Omori

; Fracalanza, Ana Paula

; Jacobi, Pedro Roberto

Cadernos de Saúde Pública

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2019, Volume 35 Nº 7 elocation e00007918

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

A abordagem do nexo urbano corresponde à compreensão e à busca de soluções integradas mediante o reconhecimento das interdependências entre água, energia e alimentos, recursos cuja escassez configura iniquidades em saúde. A hipótese central deste artigo considera que o contexto de escassez corrobora práticas sociais que podem ser sinérgicas ou contraditórias em relação aos desafios da sustentabilidade e dos direitos sociais. O objetivo é investigar sinergias e contradições a partir de práticas sociais mediante o nexo urbano no bairro Novo Recreio, na cidade de Guarulhos, Região Metropolitana de São Paulo, Brasil. A metodologia consiste em um estudo qualitativo e de base etnográfica com referência à Teoria das Práticas, com observações diretas de campo e narrativas. Os resultados apresentaram práticas sociais associadas a falta sistemática de água, precariedades na iluminação pública e no transporte, bem como dificuldade de acesso a alimentos frescos e saudáveis. O estudo das práticas sociais entre sinergias e contradições permitiu verificar que, nesse processo espontâneo de busca de solução para problemas locais, é constatada a necessidade de integrar práticas e saberes locais a políticas públicas e demandas globais. Com isso, denominamos nexos de exclusão a condição periférica de impossibilidade de opções conscientes que permitam orientar conjuntamente a redução da escassez e de iniquidades com alternativas para a sustentabilidade.

The urban nexus approach involves the investigation and elucidation of integrated solutions through the recognition of tradeoffs between water, energy, and food, namely resources whose shortage leads to inequalities in health. The article’s central hypothesis is that the context of shortage corroborates social practices that can be synergic or contradictory in relation to the challenges of sustainability and social rights. The objective is to investigate synergies and contradictions based on social practices in the urban nexus in the neighborhood of Novo Recreio in the city of Guarulhos, Greater Metropolitan São Paulo, Brazil. The methodology consists of a qualitative ethnographic study drawing on practice theory as the reference, with direct field observations and narratives. The results featured social practices associated with systematic lack of water, precarious public lighting and transportation, and difficult access to fresh and healthy foods. The study of social practices between synergies and contradictions allowed verifying that this spontaneous process of search for solutions to local problems reveals the need to incorporate local practices and knowledge into public policies and global demands. We define nexus of exclusion as the peripheral condition of impossibility of conscious options that allow jointly orienting the reduction of shortage and iniquities through alternatives for sustainability.

El abordaje del nexo urbano se corresponde con la comprensión y búsqueda de soluciones integradas, mediante el reconocimiento de las interdependencias entre agua, energía, alimentos y recursos, cuya escasez configura inequidades en salud. La hipótesis central de este artículo considera que el contexto de escasez corrobora prácticas sociales que pueden ser sinérgicas o contradictorias, a través de los desafíos en sostenibilidad y derechos sociales. Los objetivos son investigar sinergias y contradicciones, a partir de prácticas sociales mediante el nexo urbano en el barrio Novo Recreio, en la ciudad de Guarulhos, región metropolitana de São Paulo, Brasil. La metodología consiste en un estudio cualitativo y de base etnográfica, vinculado a la teoría de las prácticas, analizando observaciones de campo directas y relatos. Los resultados presentaron prácticas sociales asociadas a la falta sistemática de agua, precariedad en la iluminación pública y el transporte, dificultad de acceso a alimentos frescos y saludables. El estudio de las prácticas sociales entre sinergias y contradicciones permitió verificar que, en ese proceso espontáneo de búsqueda de soluciones para problemas locales, se constata la necesidad de integrar prácticas y saberes locales con políticas públicas y demandas globales. De esta forma, denominamos nexos de exclusión a las condiciones periféricas de imposibilidad, en cuanto a opciones conscientes que permitan orientar conjuntamente la reducción de la escasez e iniquidades con alternativas para la sostenibilidad.

https://doi.org/10.1590/0102-311x00007918

14.

Nexos de exclusão e desafios de sustentabilidade e saúde em uma periferia urbana no Brasil
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Giatti, Leandro Luiz

; Urbinatti, Alberto Matenhauer

; Carvalho, Carolina Monteiro de

; Bedran-Martins, Ana Maria

; Santos, Izabela Penha de Oliveira

; Honda, Simone Omori

; Fracalanza, Ana Paula

; Jacobi, Pedro Roberto

Cadernos de Saúde Pública

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2019, Volume 35 Nº 7 elocation e00007918

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0102-311x00007918 2217 downloads

15.

Growth Stress in Peltophorum dubium and its Correlation with the Growth Variables
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Xavier, Carolina Nogueira

; Silva, Carlos Eduardo Silveira da

; Santos, Pablo Vieira dos

; Carvalho, Alexandre Monteiro de

; Nascimento, Alexandre Miguel do

; Brancalion, Pedro Henrique Santin

Floresta e Ambiente

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2018, Volume 25 Nº 1 elocation e20160252

Resumo: En | Texto: En | PDF: En

ABSTRACT The exploitation of valuable native timber species in forest restoration projects has emerged as a promising strategy to make restoration financially viable. There are few studies regarding the quality of timber from restoration plantations. The aim of this study was to analyze growth stresses by determining the longitudinal residual strain (LRS) and evaluate their correlation with the growth variables in the species Peltophorum dubium (Spreng.) Taub in a 14-year old restoration plantation. Eighteen individuals were evaluated, determining the following variables: diameter at breast height (DBH), bark thickness, average annual growth in diameter (IMA) and annual periodic growth in diameter (IPA 2012-2015 ). The LRS was determined by the extensometer (CIRAD-Forêt), on DBH height and in the north-south direction of each tree. The LRS average was 0.072 mm, within the range of expected wood values for sawmilling. There was a significant positive correlation between the LRS, DBH and IMA.

https://doi.org/10.1590/2179-8087.025216 546 downloads

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