Pesquisa | SciELO

ABSTRACT Objective This study aimed to assess diagnostic radiology training and exposure during medical school, from the perspective of medical students in Brazil. Methods In this multicenter study approved by the Institutional Review Board, medical students from multiple universities in Brazil filled out an online questionnaire regarding their perception about diagnostic radiology training during medical school, including knowledge and use of the American College of Radiology Appropriateness Criteria and their confidence level in interpreting common radiological findings. Medical students from different regions of Brazil were sent invitations to participate in the anonymous survey through radiology group emails initiated by radiology professors and a group of ambassadors representing different institutions. Informed consent was obtained electronically at the beginning of the survey. Results The survey demonstrated diagnostic radiology is frequently included in preclinical exams; however, radiology training during medical school was considered inadequate from the medical students´ perspective. Overall, radiological imaging teaching was provided by radiologists for more than half of the survey respondents; however, radiological imaging is frequently shown to students by non-radiologist physicians during case discussion rounds. Moreover, few respondents had a mandatory radiology training rotation during medical school. Conclusion This Brazilian medical student survey demonstrated that from the medical students’ perspective, diagnostic radiology is an important subject in clinical practice; however, their radiology training and exposure are overall heterogeneous.

https://doi.org/10.31744/einstein_journal/2023ao0184

SUCEPTIBILIDAD DE Eisenia fetida (ANNELIDA, OLIGOCHAETA: LUMBRICIDAE) EXPUESTA A CEBOS CON METALDEHÍDO Y CARBARYL
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Salvio, Carla

; Clemente, Natalia Liliana

; López, Alicia Noemí

; Manetti, Pablo Luis

Ciencia del suelo

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Dez 2022, Volume 40 Nº 2 Páginas 149 - 158

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN Eisenia fetida (Annelida, Oligochaeta: Lumbricidae) es un biondicador de la contaminación del suelo y susceptible a la acción de xenobióticos como la de los fitosanitarios. El objetivo del presente trabajo fue determinar el efecto letal y subletal de tres cebos granulados en base a Metaldehído y/o Carbaryl sobre E. fetida. Se realizaron tres bioensayos bajo un diseño completamente aleatorizado con 4 repeticiones y en condiciones controladas (20±2ºC y 14L:10O). La unidad experimental fue un recipiente de plástico de 11,5 cm de diámetro y 11 cm de altura, provisto de una tapa perforada, donde se colocaron 750 g de suelo mezclado con las dosis de cada cebo y 10 individuos adultos clitelados de 200 a 400 mg. Los tratamientos fueron: 0, 40, 80, 120, 160 y 200 g de Metaldehído ha-1 (4% de ingrediente activo (i.a.)); 0, 80, 160, 240, 320 y 400 g de Carbaryl ha-1 (8% de i.a.) y 0, 40+80, 80+160, 120+240, 160+320 y 200+400 g Metaldehído+ Carbaryl ha-1 (4%+8% de i.a.). En los tres bioensayos se obtuvo el 100% de sobrevivencia de los individuos. Con respecto a la biomasa de E. fetida no se detectaron cambios con la aplicación de los cebos a los 7, 14, 21 y 28 días después de la aplicación (DDA) (p > 0,05). Por otro lado, no hubo diferencias en el número de cocones y de juveniles a los 56 DDA con todos los cebos (p> 0,05). Se concluye que los cebos en base a Metaldehído y/o Carbaryl no causaron efectos adversos sobre la sobrevivencia, la biomasa y los parámetros reproductivos de E. fetida.

ABSTRACT Eisenia fetida (Annelida, Oligochaeta: Lumbricidae) is a biondicator of soil contamination and susceptible to the action of xenobiotics such as phytosanitary. The objective of this study was to determine the lethal and sublethal effect of three granulated baits based on Metaldehyde and / or Carbaryl on E. fetida. Three bioassays were carried out under a completely randomized design with 4 repetitions and under controlled conditions (20 ± 2ºC and 14L: 10O). The experimental unit was a plastic container 11.5 cm in diameter and 11 cm in height, provided with a perforated lid, where 750 g of soil mixed with the doses of each bait and 10 clitellated adult individuals from 200 to 400 mg were placed. The treatments were: 0, 40, 80, 120, 160 and 200 g of Metaldehyde ha-1 (4% active ingredient (a.i.)); 0, 80, 160, 240, 320 and 400 g of Carbaryl ha-1 (8% of a.i.) and 0, 40 + 80, 80 + 160, 120 + 240, 160 + 320 and 200 + 400 g Metaldehyde + Carbaryl ha-1 (4% + 8% of a.i.). In the three bioassays, 100% survival of the individuals was obtained. Regarding the biomass of E. fetida, no changes were detected with the application of the baits at 7, 14, 21 and 28 days after application (DAA) (p> 0.05). On the other hand, there were no differences in the number of cocoons and juveniles at 56 DAA with all baits (p> 0.05). It is concluded that the baits based on Metaldehyde and / or Carbaryl did not cause adverse effects on survival, biomass and reproductive parameters of E. fetida.

Accessibility perception of chilean para-athletes, road to santiago 2023
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Contreras Jofré, Nicolás Felipe

; Pinochet Gilli, José Ignacio

; Aguayo Carrasco, Enrique Alejandro

; Binimelis Hermosilla, Matías

; Pérez Nuñez, Sebastián Benjamín

; Vergara Ortúzar, Rodrigo Clemente

; Muñoz Hinrichsen, Fernando

Pensar en Movimiento: Revista de ciencias del ejercicio y la salud

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Dez 2022, Volume 20 Nº 2 Páginas 56 - 74

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Contreras-Jofré, N. F., Pinochet-Gilli, J. I., Aguayo-Carrasco, E. A., Binimelis-Hermosilla, M., Pérez-Núñez, S. B., Vergara-Ortúzar, R. C. & Muñoz-Hinrichsen, F. (2022). Percepción de para atletas chilenos, rumbo a Santiago 2023, sobre la accesibilidad. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(2), 1-18. El objetivo de esta investigación es triple: 1) comprender las percepciones de los paratletas sobre la accesibilidad respecto a las futuras sedes de los Juegos Parapanamericanos Santiago 2023; 2) establecer diferencias en la percepción debidas al origen de la discapacidad y 3) documentar la percepción de paratletas con grandes necesidades de apoyo (AHSN, por sus siglas en inglés). Esta investigación es cuantitativa transversal que, en su primera etapa, desarrolló el instrumento denominado Encuesta de Percepción de Accesibilidad de Para-atletas (PPA-D, por sus siglas en inglés) y, en una segunda etapa, se aplicó a 96 paratletas chilenos (77.8% hombres, edad promedio = 31.0 ± 11.6 años). Para la prueba, se obtuvo un coeficiente de validación = .96. Respecto a las características de la muestra, 16.6% correspondió a participantes con discapacidad visual; un 35.1% era AHSN; el 51.5% estaba vinculado a la alta competencia y el 59.3% se trasladaba por su cuenta a sus entrenamientos. Se identificó una percepción negativa de la accesibilidad, principalmente en cuanto al transporte en microbús, en los elevadores y en los espacios de baños, afectando principalmente a AHSN con discapacidad visual (F1,101 = 14.01, p = .0003). Se concluye que es importante abordar las brechas de género, origen de discapacidad y AHSN para garantizar una participación equitativa bajo un marco de derecho.

Resumo Contreras-Jofré, N. F., Pinochet-Gilli, J. I., Aguayo-Carrasco, E. A., Binimelis-Hermosilla, M., Pérez-Núñez, S. B., Vergara-Ortúzar, R. C. & Muñoz-Hinrichsen, F. (2022). Percepção dos paratletas chilenos, rumo a Santiago 2023, sobre acessibilidade. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(2), 1-18. O objetivo desta pesquisa é triplo: 1) compreender as percepções dos paratletas sobre acessibilidade com relação às futuras sedes dos Jogos Parapan-Americanos de Santiago 2023; 2) estabelecer diferenças de percepção devido à origem da deficiência portada e 3) documentar a percepção de paratletas com altas necessidades de apoio (AHSN, por suas siglas em inglês). Esta pesquisa é quantitativa transversal que, em sua primeira etapa, desenvolveu o instrumento denominado Enquete de Percepção de Acessibilidade de Paratletas (PPA-D, por suas siglas em inglês) e, em uma segunda etapa, foi aplicada a 96 paratletas chilenos (77,8% homens, idade média = 31,0 ± 11,6 anos). Para o teste, obteve-se um coeficiente de validação = 0,96. Em relação às características da amostra, 16,6% corresponderam a participantes com deficiência visual; 35,1% eram AHSN; 51,5% estavam ligados à alta competência e 59,3% se deslocaram por conta própria para o treinamento. Identificou-se uma percepção negativa de acessibilidade, principalmente com relação ao transporte por micro-ônibus, elevadores e banheiros, afetando principalmente os AHSN com deficiência visual (F1.101 = 14,01, p = 0,0003). Conclui-se que é importante abordar as lacunas de gênero, origem da deficiência e AHSN para garantir uma participação equitativa ao abrigo de um quadro jurídico.

Abstract Contreras-Jofré, N. F., Pinochet-Gilli, J. I., Aguayo-Carrasco, E. A., Binimelis-Hermosilla, M., Pérez-Núñez, S. B., Vergara-Ortúzar, R. C. & Muñoz-Hinrichsen, F. (2022). Accessibility perception of chilean para-athletes, road to Santiago 2023. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 20(2), 1-18. The objective of this research is three-fold: 1) to understand Para-athletes' perceptions on accessibility regarding Santiago 2023 Parapan American games' future venues, 2) to establish differences in perception due to the origin of the disability, and 3) document alignment, if any, with athletes with high support needs (AHSN). This research is a two-phased quantitative cross-sectional study, which at the first stage developed the ''Para-athletes Perception on Accessibility Survey” (PPA-D) and, at the second stage, the survey was applied to 96 Chilean Para-athletes (77.8% men, mean age = 31.0 ± 11.6 years old). The test obtained a validation coefficient of = 0.96. Regarding the sample characteristics, 16.6% corresponded to participants with visual impairment, 35.1% were AHSN, 51.5% were linked to high-level competition, and 59.3% travelled on their own to their training sessions. A negative perception of accessibility was found, mainly concerning minibuses, elevators, and restroom spaces, affecting mostly AHSN with visual impairment (F1.101 = 14.01, p = .0003). We conclude that it is important to address gender, disability, and AHSN gaps to guarantee equitable participation under a framework of the law and social rights.

https://doi.org/10.15517/pensarmov.v20i2.49265

Prevalence of premature loss of deciduous teeth and its relationship with gender among children from Acapulco, Guerrero: a cross-sectional study
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Hernández-Palacios, Juan J.

; Castañeda-Ayala, Jovanna J.

; Juárez-Medel, Carlos A.

; Barrios-Flores, Juan E.

; Hernández-Clemente, Janitzie

; Gutiérrez-Ventura, Evangelina

Boletín médico del Hospital Infantil de México

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Out 2022, Volume 79 Nº 5 Páginas 293 - 299

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Background: Premature loss of deciduous teeth is the exfoliation or extraction before physiological replacement with < 50% or < 75% of the root of the substitute tooth formed or if there is > 1 mm of alveolar bone covering the permanent successor tooth organ. This study aimed to estimate the prevalence of premature tooth loss in children and identify associated factors in a health center in Acapulco, Guerrero. Methods: We conducted a cross-sectional study in which we collected information from 109 clinical records of children examined from January 2019 to August 2021. Sociodemographic data of the children and parents were collected: socioeconomic level, non-pathological personal history, and the history of premature deciduous tooth loss. Multivariate analysis to identify factors associated with premature deciduous tooth loss was performed with CIETmap statistical software. Odds ratio (OR) and 95% confidence interval (CI) were calculated to estimate the strength of the association. Results: The prevalence of premature loss of primary teeth was 40% (43/109). The leading cause was caries (84%, 36/43). The tooth organ with the highest loss occurrence was the lower right second molar (33%, 14/43). Gender was identified as an associated factor, with males having a higher risk of loss (ORa = 2.97; CI95% = 1.33-6.65). Conclusions: Our results were similar to those reported in other studies. Strategies aimed at health promotion directed at parents and children should be reinforced.

Resumen Introducción: Se considera como pérdida prematura de dientes deciduos a la exfoliación o extracción antes del recambio fisiológico con < 50% o < 75% de la raíz del diente sustituto formado, o si existe > 1 mm de hueso alveolar cubriendo al órgano dentario sucesor permanente. El objetivo de este trabajo fue estimar la prevalencia de pérdida prematura dental en niños e identificar factores asociados en un centro de salud de Acapulco, Guerrero. Métodos: Se llevó a cabo un estudio transversal en el que se recopiló información de 109 expedientes clínicos de niños atendidos de enero de 2019 a agosto de 2021. Se recolectaron datos sociodemográficos de los niños y los padres: nivel socioeconómico, antecedentes personales no patológicos y el antecedente de la pérdida prematura del diente deciduo. Se realizó un análisis multivariado para identificar factores asociados con la pérdida prematura de dientes deciduos con el software estadístico CIETmap. Se calcularon la razón de momios (OR) y el intervalo de confianza (IC) del 95% para estimar el grado de la asociación. Resultados: La prevalencia de pérdida prematura de dientes primarios fue del 40% (43/109). La principal causa fue por caries (84%, 36/43). El órgano dentario con más ocurrencia de pérdida fue el segundo molar inferior derecho (33%, 14/43). Se identificó el sexo como factor asociado, y se observó que el sexo masculino presenta mayor riesgo de pérdida (ORa = 2.97; IC95% = 1.33-6.65). Conclusiones: Nuestros resultados fueron similares a lo reportado en otros estudios. Deben reforzarse las estrategias de promoción de la salud dirigidas a los padres de familia y a sus hijos.

https://doi.org/10.24875/bmhim.21000230 6 downloads

Primer reporte de leucismo en la gallareta americana (Fulica americana) en el centro de México
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Gómez-Garduño, Jesús Oswaldo

; Bautista-Trejo, Rogelio

; Vázquez Sánchez, José Clemente

; Ramírez-Albores, Jorge E.

Huitzil

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Dez 2020, Volume 21 Nº 2 elocation e613

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El leucismo es una aberración cromática, definida como la ausencia de melanina, que se expresa de manera total o parcial en el plumaje de las aves. Registramos la presencia de leucismo en un individuo adulto de gallareta americana (Fulica americana) en el lago Nabor Carrillo en Texcoco, Estado de México. La gallareta americana es un ave de amplia distribución geográfica, común en hábitats acuáticos desde Alaska hasta el norte de Sudamérica. Observamos al individuo el 29 y 31 de mayo y el 26 de junio de 2020 en el cuerpo de agua. Aunque existen diversos reportes de aves con leucismo, este registro representa el primer caso documentado de leucismo para esta especie en México.

Abstract Leucism is a chromatic aberration, defined as the absence of melanin that is expressed in whole or in part of the plumage of a bird. We recorded an individual adult of American Coot (Fulica americana) with leucism in Lake Nabor Carrillo in Texcoco, State of Mexico. The American Coot is a bird with a wide geographic distribution, common in aquatic habitats from Alaska to northern South America. We observed this Coot on 29 and 31 May and 26 June 2020, in Lake Nabor Carrillo. Although there are several reports of birds with leucism, this record represents the first documented case of leucism for this species in Mexico.

https://doi.org/10.28947/hrmo.2020.21.2.495 31 downloads

BINARY MICELLES (E45S8/F127) FOR QUERCETIN AND GRISEOFULVIN SOLUBILISATION
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Lopes, Karen P. S.

; Cavalcante, Igor M.

; Silva, Raquel F. da

; Brito, Débora H. A. de

; Fechine, Lillian M. U. D.

; Moreira, Denise R.

; Vieira, Ícaro G. P.

; Azul, Francisco Vinícius Clemente S.

; Leal, Luzia K. A. M.

; Ribeiro, Maria E. N. P.

; Ricardo, Nágila M. P. S.

Química Nova

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Set 2020, Volume 43 Nº 8 Páginas 1011 - 1016

Resumo: En | Texto: En | PDF: En

Micelles have aroused interest due to their ability to assist in the transport of poorly soluble drugs. In this study the mixture of copolymers F127/E45S8 in different proportions (F/ES 30/70, 50/50 and 70/30) was performed to improve the bioavailability of griseofulvin and quercetin. The results of cytotoxicity (MTT assay) revealed that the copolymers F127 and E45S8 had considerable biocompatibility and did not affect the metabolism of human neutrophils. The binary systems were also evaluated by critical micellar concentration (CMC) and thermoresponsive behavior. The CMC values were intermediate to those of the isolated copolymers. The systems maintained the thermoresponsive properties present in F127 making the systems interesting for subcutaneous administration. The systems presented small size, an average range in size from 17 to 38 nm, and the samples prepared with higher hydrophobic proportion presented more uniform sizes. Results suggest stability and the increasing of the nanosystems circulation time. The F/ES 30/70 system has polydispersity smaller than 0.1 and showed an increase of 129 times for quercetin solubility. Thus, it is possible to consider F127/E45S8 micelles as potential nanosystems for poorly soluble drug delivery.

https://doi.org/10.21577/0100-4042.20170570 361 downloads

Optical properties of CdSe nanoparticles synthesized by hot injection in air
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Rojas-Valencia, O.G.

; Corea, M.

; Gomez-Yanez, C.

; Muñoz-Aguirre, N.

; Hernández-Pérez, I.

; Navarro-Clemente, Ma. E.

Revista mexicana de física

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Jun 2018, Volume 64 Nº 3 Páginas 275 - 282

Resumo: En | Texto: En | PDF: En

The hot injection technique is used to produce CdSe nanoparticles with quantum dot properties. There are many reports about the synthesis of quantum dots by the hot injection method; this successful synthesis approach included a semiconductor precursor, organic species such as coordinating agent trioctylphosphine (TOP) and/or trioctylphosphine oxide (TOPO). In all cases, they have considered that inert atmosphere (nitrogen or argon) is necessary for a successful synthesis, which requires specific laboratory facilities, making it cost sensitive and, consequently, complicating the experimental setup. The novelty of this work is the synthesis of CdSe under air condition instead of inert atmosphere by hot injection method, although several works report some precursors and products are highly susceptible to degradation by moisture and oxygen. The synthesis of QDs in air has the advantage that simplifies the experimental setup. To avoid undesirable interactions with oxygen, well-defined concentrations of the organic species were used during the synthesis. The influence of air over growth rate of particles was observed. To establish a comparison, the same experimental methodology was applied in both nitrogen and in air atmospheres. Results show that nanoparticles synthesized in air presented a higher growth rate than those synthesized in nitrogen at the same reaction times. Additionally, similar optical behaviors and band gaps were observed in both cases, showing the important fact that an inert atmosphere is not necessary for the synthesis of quantum dots made of CdSe nanoparticles.

663 downloads

Aprovechamiento de ñame espino post-cosecha (Dioscorea rotundata P.) en la extracción de ácido láctico
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Tejada-Tovar, Ronald E.

; Tejeda-Benítez, Lesly P.

; Tejada-Tovar, Candelaria N.

; Villabona-Ortíz, Angel

; Granados-Conde, Clemente

Prospectiva

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Jun 2018, Volume 16 Nº 1 Páginas 76 - 82

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN El objetivo del presente estudio fue obtener ácido láctico (AL) a partir del almidón de ñame espino post-cosecha (Dioscorea rotundata P.) mediante fermentación del almidón usando Lactobacillus del brueckii ssp. bulgaricus y Streptococcus thermophilus a 37ºC. Se lavaron 5 kg de tubérculos frescos, descortezaron, redujo de tamaño, licuó y filtró; el filtrado se decantó lavándose el sedimento con agua destilada, filtrados al vacío y secados a 60ºC por 12 h, seguido de molienda para su posterior empaque. El almidón se caracterizó determinando el contenido de fibra cruda, cenizas, grasa, proteínas, humedad residual y amilosa. El porcentaje de AL se determinó por titulación de 100 mL de muestra fermentada con NaOH usando fenolftaleína como indicador y la concentración se midió por cromatografía líquida de alta resolución (HPLC). Se obtuvo un almidón con un 73,22% de amilopectina, 28,7% de amilosa, 7,64% de proteína cruda, 0,26% de grasas totales, 0,88% de fibra cruda y 8,26% de humedad. Se encontró que el pH afecta significativamente las actividades enzimáticas y la asimilación de nutrientes por parte de los microorganismos utilizados y que la fermentación del almidón de ñame con los microorganismos seleccionados produjo un 16,26% de AL. Se concluye que el AL puede ser obtenido a partir del almidón de D. rotundata.

ABSTRACT The aim of the present study was obtain lactic acid (LA) from post-harvest hawthorn (Dioscorea rotundata) starch was studied by fermentation of the starch using Lactobacillus del brueckii ssp. bulgaricus and Streptococcus thermophilus at 37°C. Were washed 5 kg of fresh tubers, peeled, reduced in size, liquefied and filtered; the filtrate was decanted by washing the sediment with distilled water, vacuum filtered and dried at 60°C for 12 h, followed by milling for subsequent packing. Starch was characterized by determining the content of crude fiber, ash, grease, protein, residual moisture and amylose. The percentage of LA was determined by titration of 100 mL of NaOH fermented sample using phenolphthalein as indicator and the concentration was measured by high-performance liquid chromatography (HPLC). Was obtained a star with 73,22% of amylopectin, 28,7% of amylose, 7,64% of crude protein, 0,26% of total fats, 0,88% of crude fiber and 8,26 of humidity. It was found that pH significantly affects the enzymatic activities and the assimilation of nutrients by the microorganisms used and that the fermentation of the yam starch with the selected microorganisms produced 16,26 % of LA. From results was concluded that LA could be obtained from D. rotundata starch.

https://doi.org/10.15665/rp.v16i1.1429 497 downloads

Coproprevalencia de infestación canina por Echinococcus granulosus en un distrito endémico en hidatidosis en Perú
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Montalvo, Raúl

; Clemente, Johana

; Castañeda, Lorena

; Caro, Estephany

; Ccente, Yoli

; Nuñez, Mayori

Revista de Investigaciones Veterinarias del Perú

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Jan 2018, Volume 29 Nº 1 Páginas 263 - 269

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

The objective of this study was to determine the coproprevalence of Equinococcus granulosus in dogs of the rural district of San José de Quero, located in the province of Concepción, Junín region, central Peru. The cross-sectional study was carried out in 2015 in all three annexes of the district. Faecal samples were collected from 152 dogs from the same number of randomly selected households and processed using the Echinococcus granulosus-specific ELISA technique. The 50% of samples (Usibamba 61.0%, Chaquicocha 51.0% and San José de Quero 41.9%) were positive to the parasite. Likewise, it was determined that the average number of dogs per house was 2.3, 40.9% of the owners feed the dogs with fresh viscera of slaughtered cattle, the proportion of dogs that defecate outside the house was 91.3%, and that 18.4% reported having had a family member with a hydatid cyst. It is concluded that canine infestation by E. granulosus is frequent in the district San José de Quero, which is facilitated by the habits of the owners and the epidemiological behaviours of dogs

El objetivo del estudio fue determinar la coproprevalencia de Equinococcus granulosus en canes del distrito rural de San José de Quero, ubicado en la provincia de Concepción, región Junín, en el centro del Perú. El estudio fue observacional de tipo transversal, y se llevó a cabo en 2015 en los tres anexos del distrito. Se recolectaron muestras de heces de 152 canes del mismo número de hogares seleccionados al azar y se procesaron mediante la técnica de ELISA específica de Echinococcus granulosus. El 50% (Usibamba 61.0%, Chaquicocha 51.0% y San José de Quero 41.9%) de muestras fueron positivas al parásito. Asimismo, se determinó que el promedio de canes por casa fue 2.3, el 40.9% de los dueños alimentaba a los canes con vísceras frescas del ganado sacrificado, la proporción de perros que defecan fuera de casa era de 91.3%, y que el 18.4% refiere haber tenido algún familiar con quiste hidatídico. Se concluye que la infestación canina por E. granulosus es frecuente en el distrito San José de Quero, la cual es facilitada por los hábitos de los dueños y los comportamientos epidemiológicos del can

https://doi.org/10.15381/rivep.v29i1.14189

10.

Diffuse alveolar hemorrhage in childhoodonset systemic lupus erythematosus: a severe disease flare with serious outcome
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Blay, Gabriela

; Rodrigues, Joaquim C.

; Ferreira, Juliana C. O.

; Leal, Gabriela N.

; Gormezano, Natali W.

; Novak, Glaucia V.

; Pereira, Rosa M. R.

; Terreri, Maria T.

; Magalhães, Claudia S.

; Molinari, Beatriz C.

; Sakamoto, Ana P.

; Aikawa, Nadia E.

; Campos, Lucia M. A.

; Fernandes, Taciana A. P.

; Clemente, Gleice

; Peracchi, Octavio A. B.

; Bugni, Vanessa

; Marini, Roberto

; Sacchetti, Silvana B.

; Carvalho, Luciana M.

; Fraga, Melissa M.

; Castro, Tânia C. M.

; Ramos, Valéria C.

; Bonfá, Eloisa

; Silva, Clovis A.

Advances in Rheumatology

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2018, Volume 58 elocation 39

Resumo: En | Texto: En | PDF: En

Abstract Objective: To evaluate prevalence, clinical manifestations, laboratory abnormalities and treatment in a multicenter cohort study including 847 childhood-onset systemic lupus erythematosus (cSLE) patients with and without diffuse alveolar hemorrhage (DAH), as well as concomitant parameters of severity. Methods: DAH was defined as the presence of at least three respiratory symptoms/signs associated with diffuse interstitial/alveolar infiltrates on chest x-ray or high-resolution computer tomography and sudden drop in hemoglobin levels. Statistical analysis was performed using Bonferroni correction (p < 0.0022). Results: DAH was observed in 19/847 (2.2%) cSLE patients. Cough/dyspnea/tachycardia/hypoxemia occurred in all cSLE patients with DAH. Concomitant parameters of severity observed were: mechanical ventilation in 14/19 (74%), hemoptysis 12/19 (63%), macrophage activation syndrome 2/19 (10%) and death 9/19 (47%). Further analysis of cSLE patients at DAH diagnosis compared to 76 cSLE control patients without DAH with same disease duration [3 (1–151) vs. 4 (1–151) months, p = 0.335], showed higher frequencies of constitutional involvement (74% vs. 10%, p < 0.0001), serositis (63% vs. 6%, p < 0.0001) and sepsis (53% vs. 9%, p < 0.0001) in the DAH group. The median of disease activity score(SLEDAI-2 K) was significantly higher in cSLE patients with DAH [18 (5–40) vs. 6 (0–44), p < 0.0001]. The frequencies of thrombocytopenia (53% vs. 12%, p < 0.0001), intravenous methylprednisolone (95% vs. 16%, p < 0.0001) and intravenous cyclophosphamide (47% vs. 8%, p < 0.0001) were also significantly higher in DAH patients. Conclusions: This was the first study to demonstrate that DAH, although not a disease activity score descriptor, occurred in the context of significant moderate/severe cSLE flare. Importantly, we identified that this condition was associated with serious disease flare complicated by sepsis with high mortality rate.

https://doi.org/10.1186/s42358-018-0038-4 467 downloads

11.

SDSS IV - Manga properties of AGN Host Galaxies
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Sánchez, S. F.

; Avila-Reese, V.

; Hernandez-Toledo, H.

; Cortes-Suárez, E.

; Rodríguez-Puebla, A.

; Ibarra-Medel, H.

; Cano-Díaz, M.

; Barrera-Ballesteros, J. K.

; Negrete, C. A.

; Calette, A. R.

; Lorenzo-Cáceres, A. de

; Ortega-Minakata, R. A.

; Aquino, E.

; Valenzuela, O.

; Clemente, J. C.

; Storchi-Bergmann, T.

; Riffel, R.

; Schimoia, J.

; Riffel, R. A.

; Rembold, S. B.

; Brownstein, J. R.

; Pan, K.

; Yates, R.

; Mallmann, N.

; Bitsakis, T.

Revista mexicana de astronomía y astrofísica

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2018, Volume 54 Nº 1

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract We present the characterization of the main properties of a sample of 98 AGN host galaxies, both type-II and type-I, in comparison with those of ≈2700 non-active galaxies observed by the MaNGA survey. We found that AGN hosts are morphologically early-type or early-spirals. AGN hosts are, on average, more massive, more compact, more centrally peaked and more pressure-supported systems. They are located in the intermediate/transition region between star-forming and non-starforming galaxies (i.e., the so-called green valley). We consider that they are in the process of halting/quenching the star formation. The analysis of the radial distributions of different properties shows that the quenching happens from inside-out involving both a decrease of the efficiency of the star formation and a deficit of molecular gas. The data-products of the current analysis are distributed as a Value Added Catalog within the SDSS-DR1411.

Resumen Presentamos la caracterización de las propiedades de 98 galaxias que albergan AGN, tanto de Tipo-I como de Tipo-II, en comparación con ≈2700 galaxias no activas extraídas del mapeado MaNGA. Las galaxias con AGN son de tipo temprano y espirales tempranas. Las galaxias con AGN son, en promedio, más masivas, compactas y concentradas en las partes centrales que las no activas, además de estar más soportadas por presión. Las galaxias con AGN se encuentran en la zona de transición entra las galaxias con formación estelar y las que no forman estrellas (valle verde), estando en el proceso de inhibir/detener su formación estelar. Las distribuciones radiales de diferentes propiedades muestran que esta inhibición ocurre desde dentro hacia fuera, debido a un decremento tanto de la eficiencia de la formación estelar como del gas molecular. Los productos de este análisis están disponibles como un Catálogo de Valor Añadido incluido en el SDSS-DR1411.

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12.

Synthesis, Characterization and Dielectric Properties of New 5-(4-Hydroxyphenyl)- 10,15,20-tri-4-[2-(3-pentadecylphenoxy)ethoxy]phenyl porphyrin and Their Ni, Co and Cu Complexes
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Mota, João P. F.

; Costa Júnior, Antônio E. da

; Ribeiro, Viviane G. P.

; Sampaio, Samuel G.

; Lima, Nayane M. A.

; Silva, Fernando L. F. da

; Clemente, Claudenilson S.

; Mele, Giuseppe

; Lomonaco, Diego

; Mazzetto, Selma E.

Journal of the Brazilian Chemical Society

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Jun 2017, Volume 28 Nº 6 Páginas 1063 - 1073

Resumo: En | Texto: En | PDF: En

New asymmetric cardanol-based porphyrins, free-base and coordinated with Ni, Co and Cu, were synthesized and completely characterized as A3B type. Such porphyrins were obtained aiming improved solubility in polar solvents due insertion of an -OH phenolic group. Their thermal and dielectric properties were also evaluated. Changes in the synthetic route reduced the reaction time and improved the yields of the aldehyde precursor obtainment. Electronic absorption spectra of the new porphyrins in CH2Cl2, EtOH and acetone, indicated a decrease in the ε (molar absorptivity) values with increasing solvent polarity, except for the nickel complex which, in acetone, showed a slight increase of 2% in the ε value. The dielectric measurements showed that the conductivity (σ) and the loss tangent (tan δ) increased with frequency, but the permittivity (ε') decreased. The results showed that the coordination of the porphyrin promoted a significant change in thermal and dielectric properties, specially for to the Ni-complex compound, which presented the best dielectric properties with interesting values of permittivity and loss tangent at 100 MHz (19.46 and 0.011 a.u., respectively).

https://doi.org/10.21577/0103-5053.20160261 1177 downloads

13.

Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum,
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Melo, Larisse Rayanne Miranda de

; Clemente, Heleni Aires

; Bezerra, Dalila Fernandes

; Dantas, Raquel Costa Silva

; Ramalho, Héryka Myrna Maia

; Dimenstein, Roberto

Jornal de Pediatria

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Fev 2017, Volume 93 Nº 1 Páginas 40 - 46

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo: Objetivo: Avaliar o efeito da suplementação materna com vitamina E sobre a concentração de α-tocoferol no colostro e o fornecimento dessa para o recém-nascido. Método: O estudo clínico randomizado foi feito com 99 parturientes adultas e saudáveis, 39 alocadas no grupo controle e 60 no grupo suplementado. Após jejum noturno, foram coletados 5 mL de sangue e 2 mL de colostro das parturientes. Após a primeira coleta (leite 0 h), o grupo suplementado recebeu suplementação com 400 UI de vitamina E. Foi feita nova coleta de 2 mL de colostro, em ambos os grupos, 24 h após a suplementação (leite 24 h). As amostras foram analisadas por cromatografia líquida de alta eficiência. A quantidade de α-tocoferol fornecida pelo colostro foi considerada para uma ingestão diária de 396 mL de leite e comparada com a ingestão diária recomendada para crianças de 0 a 6 meses (4 mg/dia). Resultados: A concentração média inicial de α-tocoferol no colostro foi de 1.509,3 ± 793,7 µg/dL no grupo controle e 1.452,9 ± 808,6 µg/dL no grupo suplementado. Após 24 horas a concentração média de α-tocoferol no grupo controle foi de 1.650,6 ± 968,7 µg/dL (p > 0,05) e de 2.346,9 ± 1203,2 µg/dL (p < 0,001) no grupo suplementado. Aumentou-se assim a oferta de vitamina E para o recém-nascido para 9,3 mg/dia. Inicialmente 18 mulheres do grupo suplementado forneciam valores inferiores a 4 mg/dia de α-tocoferol em seu colostro, após suplementação apenas seis continuaram a fornecer quantidade inferior ao recomendado. Conclusão: A suplementação materna com vitamina E promove o aumento do fornecimento da vitamina para o recém-nascido e fornece mais do que o dobro da ingestão diária recomendada.

Abstract: Objective: To evaluate the effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum and its supply to the newborn. Method: This randomized clinical trial enrolled 99 healthy adult pregnant women; of these, 39 were assigned to the control group and 60 to the supplemented group. After an overnight fast, 5 mL of blood and 2 mL of colostrum were collected. After the first sampling (0 h milk), the supplemented group received 400 IU of supplementary vitamin E. Another 2 mL milk aliquot was collected in both groups 24 h after supplementation (24 h milk). The samples were analyzed by high-performance liquid chromatography. The α-tocopherol content provided by colostrum was calculated by considering a daily intake of 396 mL of milk and comparing the resulting value to the recommended daily intake for infants aged 0-6 months (4 mg/day). Results: The initial mean concentration of α-tocopherol in colostrum was 1509.3 ± 793.7 µg/dL in the control group and 1452.9 ± 808.6 µg/dL in the supplemented group. After 24 h, the mean α-tocopherol concentration was 1650.6 ± 968.7 µg/dL in the control group (p > 0.05) and 2346.9 ± 1203.2 µg/dL in the supplemented group (p < 0.001), increasing the vitamin E supply to the newborn to 9.3 mg/day. Initially, 18 women in the supplemented group provided colostrum α-tocopherol contents below 4 mg/day; after supplementation only six continued to provide less than the recommended amount. Conclusion: Maternal vitamin E supplementation increases the supply of the vitamin to the infant by providing more than twice the Recommended Daily Intake.

https://doi.org/10.1016/j.jped.2016.03.007 2294 downloads

14.

Evaluación de algunas características físicas y químicas de frutos de xocotuna, tuna y xoconostle en poscosecha
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Monroy-Gutiérrez, Teresa

; Martínez-Damián, Ma.Teresa

; Barrientos-Priego, Alejandro F.

; Gallegos-Vázquez, Clemente

; Rodríguez-Pérez, Juan E.

; Colinas-León, Ma. Teresa B.

Revista mexicana de ciencias agrícolas

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Fev 2017, Volume 8 Nº 1 Páginas 189 - 197

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract The objective of the present investigation was to determine some physical and chemical characteristics of xocotuna in comparison with tuna and xoconostle. The fresh fruits of xocotuna, tuna and xoconostle were used in physiological maturity. The percentage of weight loss, color (hue angle), shell thickness, total soluble solids and titratable acidity were evaluated. It was found that weight loss was similar between tunas and xocotunas, and greater than 8% in the xoconostles. The pitch angle had a tendency to decrease and increase during the evaluated period due to the increase of color of the pulp of the fruit. The thickness of the peel was different between cultivars and decreased as the evaluation time passed as a consequence of the ripening process. It was observed that the xoconostles presented lower content of total soluble solids unlike the tunas and xocotunas. Similar values of titratable acidity were observed between the cultivars of tuna and xocotuna, and in xoconostles, higher values.

Resumen El objetivo de la presente investigación fue determinar algunas características físicas y químicas de xocotuna en comparación con tuna y xoconostle. Se utilizaron frutos de xocotuna, tuna y xoconostle frescos en madurez fisiológica. Se evaluó el porcentaje de pérdida de peso, color (ángulo hue), grosor de cáscara, sólidos solubles totales y acidez titulable. Se encontró que la pérdida de peso fue similar entre tunas y xocotunas, y mayor a 8% en los xoconostles. El ángulo de tono tuvo una tendencia a disminuir y aumentar durante el periodo evaluado debido al incremento de color de la pulpa del fruto. El grosor de la cáscara fue diferente entre cultivares y disminuyó conforme paso el tiempo de evaluación como consecuencia del proceso de maduración. Se observó que los xoconostles presentaron menor contenido de sólidos solubles totales a diferencia de las tunas y xocotunas. Se observaron valores similares de acidez titulable entre los cultivares de tuna y xocotuna, y en xoconostles valores más altos.

https://doi.org/10.29312/remexca.v8i1.82 783 downloads

15.

Panorámica internacional en relación a las recomendaciones, práctica clínica y legislación del parto en casa
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Ortega Barreda, E.

; Cairós Ventura, L.M.

; Clemente Concepción, J.A.

; Rojas Linares, C.

; Pérez González, A.M.

Ene

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2017, Volume 11 Nº 1

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Introduction: The choice of a child's birthplace is a family right recognized for years. Providing the necessary information to take the right decision is an obligation for health care professionals. Objective: To compare clinical practice, legislation and requirements in countries with higher rates of childbirths at home. Methods: A bibliographical search is carried out in the different databases and an intended search in professional colleges of midwives and nurses as well. Results: Similarity is observed in clinical practice but the legislation, funding and requirements for its practice vary significantly from country to country. Discussion and conclusions: The safety of childbirth at home continues being a source of discrepancy among health care professionals and is the reason for important differences in international policies.

Introducción: La elección del lugar de nacimiento de un hijo es un derecho de las familias reconocido desde hace años. Facilitar la información necesaria para la toma de decisiones es una obligación de los profesionales sanitarios. Objetivo: Comparar la práctica clínica, legislación y requisitos en los países con mayores tasas de partos en domicilio. Metodología: Se realiza búsqueda bibliográfica en las diferentes bases de datos e intencionada en los diferentes colegios profesionales de matronas y enfermeras. Resultados: Se observa similitud en la práctica clínica pero la legislación, financiación y requisitos para su práctica varían significativamente de un país a otro. Discusión y conclusiones: La seguridad del parto en el hogar sigue siendo motivo de discrepancia entre los profesionales sanitarios y motivo de importantes diferencias en las políticas internacionales.

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