ABSTRACT Background: Omalizumab (OMA) is approved for antihistamine resistant chronic spontaneous urticaria (CSU). The possibility of self-administration (SA), is particularly convenient in current pandemic scenario, avoiding commutements to the hospital. Objectives: CSU control, SA safety, satisfaction, and cost reduction for patients under OMA SA therapy, during a period ≥ 12 weeks and after 2 training sessions in Outpatient Hospital Care (OHC) were evaluated between January and June 2021. Methods: A questionnaire (30 questions) was applied for the characterization of clinical/demographic data, therapy, adverse reactions (AR) and advantages/concerns related to OMA SA. Clinical evaluation of CSU was performed in T0 (last administration in OHC) and T1 (at12 weeks on SA), by urticaria activity score in the last 7 days (UAS7), urticaria control test (UCT) and dermatology life quality index (DLQI). Results: Twenty-five patients with a mean CSU duration of 7.4 ±3.9 years and under OMA for 3.2 ±1.9 years were included. At the time of the questionnaire, 52% had already 3 SA of OMA 300mg, with variable periodicity between 4/4 week (44%) and 8/8 week (12%); 40% without antihistamine H1 (anti-H1) therapy associated. In 88% OMA was SA by patient himself. 64% perceived equal pain intensity with SA than in OHC administration. No serious AR were reported. Regarding the control of CSU, there were no statistically significant differences between scores in T0 and T1. SA was considered advantageous by all patients, being valued the reduction of time/costs. About 48% reported some concerns with SA, especially in OMA manipulation. The majority (76%) considered a simple and practical procedure, valuing initial training sessions in OHC. For 52% there was no need for further improvement, while the simplification of the OMA delivery process was proposed by 28% of patients. Conclusions: OMA SA had a positive impact on satisfaction in patients with CSU, keeping up the good control and therapeutic safety.

RESUMO Fundamentos: O omalizumab (OMA) está aprovado para a urticária crónica espontânea (UCE) refratária aos anti-histamínicos. A possibilidade de autoadministração (AA) de OMA evita deslocações ao hospital, particularmente relevante em tempo de pandemia. Objetivos: Avaliaram-se o controlo da UCE, segurança da AA de OMA, grau de satisfação e redução dos custos para os doentes sob OMA em AA por período igual ou superior a 12 semanas e após duas sessões de ensino em Hospital de Dia (HD), entre janeiro e junho de 2021. Métodos: Aplicou-se um questionário(30 perguntas) visando a caracterização clínica/demográfica, terapêutica, reações adversas (RA), vantagens/preocupações percecionadas e avaliação de UCE em T0 (última administração em HD) e T1 (12 semanas em AA), por score de atividade da urticária nos últimos sete dias (UAS7), teste de controlo da urticária (UCT) e índice de qualidade de vida em dermatologia (DLQI). Resultados: Incluíram-se 25 doentes com tempo médio de UCE de 7,4 ±3,9 anos e duração do tratamento com OMA de 3,2 ±1,9 anos. À data do questionário, 52% tinham 3 AA de OMA 300mg, com periodicidade variável entre 4/4 semanas (44%) e 8/8 semanas (12%); 40% sem anti-histamínico associado. Em 88% administrado pelo próprio; 64% relatou igual intensidade de dor na AA face à administração em HD. Não se registaram RA graves. No controlo da UCE não se verificaram diferenças estatisticamente significativas nos scores entre T0 e T1. Todos consideraram a AA vantajosa, valorizando sobretudo a diminuição do tempo/custos despendidos. 48% referiu algum receio na AA, sobretudo na manipulação do OMA. A maioria (76%) considerou o processo simples e prático, valorizando os ensinos prévios em HD; 52% considerou não haver aspetos a melhorar; das sugestões apontadas, 28% referiam-se à simplificação do processo de entrega do OMA. Conclusões: O OMA em AA apresentou impacto positivo na satisfação dos doentes com UCE, mantendo-se o controlo da UCE e segurança terapêutica.

RESUMO Objetivo: Avaliar a doença das pequenas vias aéreas em pacientes com COVID-19 por meio da prevalência de aprisionamento aéreo (AA) e sua correlação com desfechos clínicos. Também foi avaliada a relação entre opacidades tomográficas nos pequenos vasos sanguíneos e ventilação em pacientes com pneumonia por SARS-CoV-2. Métodos: Foram incluídos, retrospectivamente, 53 pacientes com teste de RT-PCR positivo para SARS-CoV-2 entre março e abril de 2020. Todos os indivíduos foram submetidos à TCAR, incluindo aquisições inspiratórias e expiratórias. Os indivíduos foram divididos em dois grupos com base na identificação visual de AA. Os volumes dos pequenos vasos sanguíneos foram estimados por meio de seções transversais < 5 mm2 (VS5) derivadas de algoritmos automatizados de segmentação. Modelos de efeito misto foram obtidos para representar o VS5 em função das opacidades lobares tomográficas e da ventilação lobar. Resultados: Identificou-se AA em 23 (43,4%) dos 53 participantes. A presença de AA apresentou associação com SpO2 elevada na admissão (OR = 1,25; IC95%: 1,07-1,45; p = 0,004) e níveis reduzidos de dímero D (OR = 0,99; IC95%: 0,99-0,99; p = 0,039). Pacientes com AA apresentaram menor probabilidade de hospitalização (OR = 0,27; IC95%: 0,08-0,89; p = 0,032). Houve correlação inversa significativa, mas fraca, entre VS5 e opacidades lobares tomográficas (R2 = 0,19; p = 0,03) e correlação direta não significativa e fraca entre VS5 e ventilação lobar (R2 = 0,08; p = 0,54). Conclusões: AA é um achado comum em pacientes com COVID-19 submetidos à TC expiratória. A presença de AA pode apresentar correlação com SpO2 elevada na admissão, níveis reduzidos de dímero D e menor probabilidade de hospitalização. Além disso, o volume dos pequenos vasos pulmonares pode apresentar correlação negativa com opacidades tomográficas, mas não com ventilação lobar.

ABSTRACT Objective: To evaluate small airway disease in COVID-19 patients using the prevalence of air trapping (AT) and correlating it with clinical outcomes. The relationship between CT-based opacities in small blood vessels and ventilation in patients with SARS-CoV-2 pneumonia was also assessed. Methods: We retrospectively included 53 patients with positive RT-PCR results for SARS-CoV-2 between March and April of 2020. All subjects underwent HRCT scanning, including inspiratory and expiratory acquisitions. Subjects were divided into two groups based on visual identification of AT. Small blood vessel volumes were estimated by means of cross-sectional areas < 5 mm2 (BV5) derived from automated segmentation algorithms. Mixed-effect models were obtained to represent the BV5 as a function of CT-based lobar opacities and lobar ventilation. Results: Of the 53 participants, AT was identified in 23 (43.4%). The presence of AT was associated with increased SpO2 at admission (OR = 1.25; 95% CI, 1.07-1.45; p = 0.004) and reduced D-dimer levels (OR = 0.99; 95% CI, 0.99-0.99; p = 0.039). Patients with AT were less likely to be hospitalized (OR = 0.27; 95% CI, 0.08-0.89; p = 0.032). There was a significant but weak inverse correlation between BV5 and CT-based lobar opacities (R2 = 0.19; p = 0.03), as well as a nonsignificant and weak direct correlation between BV5 and lobar ventilation (R2 = 0.08; p = 0.54). Conclusions: AT is a common finding in patients with COVID-19 that undergo expiratory CT scanning. The presence of AT may correlate with higher SpO2 at admission, lower D-dimer levels, and fewer hospitalizations when compared with absence of AT. Also, the volume of small pulmonary vessels may negatively correlate with CT opacities but not with lobar ventilation.

Abstract Objective: The aim of this study was to evaluate the association of -924 G>A (rs2232365) and -3279 C>A (rs3761548) FOXP3 variants with IBD susceptibility, clinical and endoscopic activity, and IL-10 and TGF-β1 plasma levels. Method: The study included 110 IBD female patients, 60 with Ulcerative Colitis (UC) and 50 with Crohn’s Disease (CD), and 154 female controls. FOXP3 variants were determined with Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Plasma levels of IL-10 and TGF-β1 were determined using immuno-fluorimetric assay. Results: AA genotype of rs2232365 and rs3761548 was associated with CD (OR = 3.147, 95% CI 1.015-9.758, p = 0.047) and UC (OR = 3.221, 95% CI 1.050-9.876, p = 0.041) susceptibility, respectively. However, were not associated with TGF-β1 and IL-10 levels, and endoscopic/clinical activity disease. GAGA haplotype was associated with IBD (OR = 4.003, 95% CI 1.100–14.56, p = 0.035) and UC susceptibility (OR = 6.107, 95% CI 1.609–23.18, p = 0.008). In addition, IBD patients with the GAGA haplotype had lower TGF-β1 levels (p = 0.041). Moreover, G/C haplotype (dominant model) had a protective effect of 60% in CD susceptibility and lower Endoscopic Severity Index. Conclusions: These results suggest that FOXP3 variants could exert a role in the Treg, which could be one of the factors involved in the susceptibility and pathogenesis of IBD.

ABSTRACT (150 words) (same order that title) The practice of sports has been considered one of the main tools for the life skills development among youth sport participants. This cross-sectional study investigated the predicting role of age and time of practice in the development of life skills among 207 male youth futsal practitioners from the state of Pernambuco, Brazil. The instruments used were the Life Skills Scale for Sports and a semi-structured questionnaire. Data analysis was conducted through Multivariate Analysis of Variance, Pearson's correlation and Multiple Regression (p<.05). The results showed significant difference (p<.05; η2=.036-.142) in all life skills according to age group, evidencing higher scores for older adolescents. Further, more experienced adolescents showed higher scores at goal seating (p=.001, η2=.074); problems solving (p=.013, η2=.042), communication (p=.003, η2=.054) and total life skills (p=.002, η2=.057). There was significant (p<.05) and positive correlation between age and almost all life skills subscales. Multiple regression revealed only age presented positive prediction toward life skills. It can be concluded that age is a predictor of life skills development among youth futsal practitioners.

RESUMO (1500 palavras) (mesma ordem como títulos) A prática esportiva tem sido considerada uma das principais ferramentas para o desenvolvimento de habilidades para a vida entre jovens praticantes de esportes. Este estudo transversal investigou o papel preditivo da idade e do tempo de prática no desenvolvimento de habilidades para a vida em 207 jovens praticantes de futsal do sexo masculino do estado de Pernambuco, Brasil. Os instrumentos utilizados foram a Escala de Habilidades para a Vida Esportiva e um questionário semiestruturado. A análise dos dados foi realizada por meio da Análise Multivariada de Variância, correlação de Pearson e Regressão Múltipla (p<0,05). Os resultados mostraram diferença significativa (p<0,05; η2=0,036-0,142) em todas as habilidades para a vida de acordo com a faixa etária, evidenciando escores mais altos nos adolescentes mais velhos. Além disso, os adolescentes mais experientes apresentaram pontuações mais altas nos assentos para as metas (p=0,001; η2=0,074); resolução de problemas (p=0,013, η2=0,042), comunicação (p=0,003, η =0,054) e habilidades totais para a vida (p=0,002, η2=0,057). Houve correlação significativa (p<0,05) e positiva entre idade e quase todas as subescalas de habilidades para a vida. A regressão múltipla revelou que apenas a idade apresentou predição positiva em relação às habilidades para a vida. Pode-se concluir que a idade é um preditor do desenvolvimento de habilidades para a vida entre jovens praticantes de futsal.

RESUMEN (150 palabras) (mismo orden que títulos) La práctica del deporte ha sido considerada una de las principales herramientas para el desarrollo de habilidades para la vida entre los jóvenes participantes en el deporte. Este estudio transversal investigó el papel predictivo de la edad y el tiempo de práctica en el desarrollo de habilidades para la vida entre 207 practicantes de futsal masculinos del estado de Pernambuco, Brasil. Los instrumentos utilizados fueron la Escala de habilidades para la vida deportiva y un cuestionario semiestructurado. El análisis de los datos se realizó a través del Análisis de varianza multivariante, la correlación de Pearson y la Regresión múltiple (p<.05). Los resultados mostraron una diferencia significativa (p <.05; η2=.036-.142) en todas las habilidades para la vida según el grupo de edad, evidenciando puntuaciones más altas para los adolescentes mayores. Además, los adolescentes más experimentados mostraron puntajes más altos en la meta sentada (p=.001, η2=.074); resolución de problemas (p=.013, η2=.042), comunicación (p=.003, η2=.054) y habilidades para la vida total (p=.002, η2=.057). Hubo una correlación significativa (p<.05) y positiva entre la edad y casi todas las subescalas de habilidades para la vida. La regresión múltiple reveló que solo la edad presentaba predicciones positivas hacia las habilidades para la vida. Se puede concluir que la edad es un predictor del desarrollo de habilidades para la vida entre los jóvenes practicantes de fútbol sala.

Abstract: The aim of this study was to evaluate patient perception of surgical discomfort in third molar surgery and the association with clinical variables and polymorphisms associated with the FKBP5, SLC6A4, and COMT genes. This cross-sectional observational study was carried out on 196 participants aged between 18 and 64 years at the Federal University of Paraná in 11 months. The intensity of surgical discomfort was assessed using the QCirDental questionnaire. Data on surgical and individual procedures were also cataloged. The oral health related quality of life was assessed by the Oral Health Impact Profile questionnaire (OHIP-14). The DNA sample was obtained from cells of the oral mucosa. Five markers of the FKBP5, SLC6A4, and COMT genes were genotyped. The data were submitted to statistical analysis with a significance level of 5%. Women reported greater intensity of discomfort associated with third molar surgery compared to men (p = 0.001). In the recessive model, the AA genotype of the rs3800373 marker was associated with greater surgical discomfort (p = 0.026). Therefore, women and individuals of the AA genotype for the rs3800373 marker in the FKBP5 gene reported greater surgical discomfort associated with third molar surgery.

RESUMO Objetivo: Avaliar a associação entre a prevalência de asma e níveis séricos de vitamina D em adolescentes brasileiros. Métodos: Estudo transversal de base escolar com adolescentes de 12 a 17 anos provenientes de quatro grandes cidades brasileiras em diferentes latitudes (Fortaleza, Rio de Janeiro, Brasília e Porto Alegre). Informações sobre o diagnóstico de asma, estilo de vida e características sociodemográficas foram coletadas por meio de questionários autoaplicáveis. As concentrações séricas de calcifediol foram dicotomizadas: suficientes (≥ 20 ng/mL) e insuficientes/deficientes (< 20 ng/mL). Foram realizadas análises bivariadas entre os níveis de vitamina D e a prevalência de asma ativa (AA), além de outras variáveis, por meio do teste do qui-quadrado. Modelos lineares generalizados foram configurados para analisar possíveis fatores de confusão (p < 0,20). Resultados: Entre 2013 e 2014, foram avaliados 1.053 adolescentes. A prevalência de AA e níveis insuficientes/deficientes de calcifediol foram de 15,4% e 21%, respectivamente. Não houve associações estatisticamente significativas entre AA e hipovitaminose D. As prevalências de AA e insuficiência de vitamina D foram, respectivamente, 2,34 (IC95%: 1,28-4,30) e 3,22 (IC95%: 1,75-5,95) vezes maiores em Porto Alegre que no Rio de Janeiro, independentemente de possíveis fatores de confusão. No entanto, não foram observadas associações significativas entre a prevalência de AA e variáveis relacionadas à vitamina D em nenhuma das cidades. Conclusões: Não se observou nenhuma associação entre AA e níveis baixos de vitamina D em adolescentes residentes em diferentes latitudes no Brasil.

ABSTRACT Objective: To evaluate the association between asthma prevalence and serum levels of vitamin D in Brazilian adolescents. Methods: This was a cross-sectional, school-based study involving adolescents between 12-17 years of age from four large Brazilian cities located at different latitudes (Fortaleza, Rio de Janeiro, Brasília, and Porto Alegre). Information on asthma diagnosis, lifestyle, and sociodemographic characteristics was collected by means of self-administered questionnaires. Serum concentrations of calcifediol were dichotomized as sufficient (≥ 20 ng/mL) or insufficient/deficient (< 20 ng/mL) levels. Bivariate analyses were carried out between vitamin D levels and prevalence of active asthma (AA), as well as other variables in study, using the chi-square test. Generalized linear models were configured to analyze potential confounding factors (p < 0.20). Results: Between 2013 and 2014, 1,053 adolescents were evaluated. The prevalences of AA and insufficient/deficient levels of calcifediol were 15.4% and 21%, respectively. There were no statistically significant associations between AA and hypovitaminosis D. The prevalences of AA and vitamin D insufficiency were, respectively, 2.34 (95% CI, 1,28-4.30) and 3.22 (95% CI, 1.75-5.95) times higher in Porto Alegre than in Rio de Janeiro, regardless of possible confounding factors. However, no significant associations were found between the prevalence of AA and vitamin-D-related variables in any of the cities. Conclusions: No association was found between AA and low levels of vitamin D in adolescents living at different latitudes in Brazil.

Resumo Objetivo analisar a prevalência e os fatores associados à triagem da COVID-19 e propor as estratégias necessárias para a reabertura das Escolas de Enfermagem universitárias para as aulas presenciais. Métodos um estudo transversal foi projetado a partir da linha de base de uma pesquisa longitudinal baseada na Internet de uma Escola Brasileira de Enfermagem. Com o resultado ordinal (classificação operacional COVID-19), a análise de dados foi conduzida usando um modelo de regressão multinomial. Resultados um total de 498 participantes foi incluído na análise e revelou 67,27% de casos suspeitos e 11,65% de casos confirmados de COVID-19. O uso de máscaras, o transporte público e fazer parte da linha de frente dos trabalhadores da saúde foram estatisticamente associados a um histórico positivo para a COVID-19. Conclusão os planos de reabertura de Escolas de Enfermagem devem integrar o uso de equipamentos de proteção pessoal, o transporte público e a triagem da COVID-19 na educação.

Abstract Objective to analyze the prevalence and factors associated with COVID-19 screening and propose the necessary strategies for the reopening of university Nursing Schools to face-to-face classes. Methods aa cross-sectional study was designed from the baseline of a longitudinal Internet-based survey of a Brazilian School of Nursing. With the ordinal outcome (COVID-19 operational classification), data analysis was conducted using a multinomial regression model Results a total of 498 participants were included in the analysis and revealed 67.27% suspected and 11.65% confirmed cases of COVID-19. Wearing masks, public transportation, and being part of frontline healthcare workers were statistically associated with a positive history for COVID-19. Conclusion plans to reopen Nursing Schools must integrate the use of personal protective equipment, public transportation, and COVID-19 screening into education.

Resumen Objetivo analizar la prevalencia y los factores asociados al rastreo de COVID-19 y proponer las estrategias necesarias para la reapertura de Escuelas Universitarias de Enfermería para clases presenciales. Métodos se diseñó un estudio transversal a partir de la línea de base de una investigación longitudinal basada en Internet de una Escuela Brasileña de Enfermería. Con el resultado ordinal (clasificación operativa COVID-19), se realizó el análisis de datos mediante un modelo de regresión multinomial. Resultados se incluyeron en el análisis un total de 498 participantes que revelaron el 67,27% de los casos sospechosos y el 11,65% de los casos confirmados de COVID-19. El uso de máscaras, el transporte público y ser parte de la primera línea de los trabajadores de la salud se asociaron estadísticamente con un historial positivo de COVID-19. Conclusión los planes de reapertura de Escuelas de Enfermería deben integrar el uso de equipos de protección personal, transporte público y el rastreo de COVID-19 en la educación.

Abstract The properties of aluminum alloys can be improved by the processing conditions that cause changes in the microstructure and by the addition of alloy elements. In order to understand the physical behavior and mechanical properties of aluminum alloys, it is important to be aware of some of the microstructural characteristics. Some of these characteristics are the morphology, alloy elements, volume and size, and second phase. In this study, we analyzed the effect of annealing on the mechanical and microstructural properties of the laminated AA 5182 aluminum alloy, when subjected to different annealing conditions. The alloy was heated to temperatures of 50º C, 100º C, 150º C, 200º C, 250º C and 300º C for 10 minutes and left to cool naturally. The evolution of the microstructure was characterized by optical and electronic microscopy with EDS, and, to obtain the mechanical properties, a tensile test was performed and the fractures were subsequently analyzed. The results showed that the heat treatment used reduced the amount of second phase particles and this influenced the mechanical properties.

Resumen En este estudio se objetivó evaluar los efectos del agua de fertirrigación con efluente de alcantarillado doméstico y de diferentes sustratos de cultivo en el crecimiento de mudas de Caraíba (Tabebuia aurea Benth). El experimento fue realizado en condiciones de ambiente protegido en la ciudad de Mossoró, RN. Se han probado cinco soluciones de riego (100% de agua de abastecimiento - AA, 100% de efluente de desagüe doméstico - EE y las diluciones del 75% EE + 25% AA, 50% EE + 50% AA y 25% EE + 75 (% AA) y dos sustratos (75% suelo + 25% estiércol de bovinos y 75% suelo + 25% fibra de coco) utilizando el delineamiento estadístico completamente casualizado, arregladas en parcelas subdivididas con tres repeticiones por tratamiento. Las evaluaciones de crecimiento y desarrollo se realizaron a los 30, 60, 90 y 150 días después de la siembra. Se determinaron las variables altura de la parte aérea, diámetro del cuello, relación entre altura y diámetro, materias secas del sistema radicular, de la parte aérea y total (raíz y parte aérea), relación entre raíz y parte aérea, índice de Dickson, y la evaluación nutricional de nitrógeno, fósforo, potasio y calcio. Se verificó que la utilización de efluente doméstico aumentó el crecimiento y la calidad de las mudas de caraíba, además de promover la acumulación nutricional en las plantas cultivadas en sustrato de estiércol bovino más suelo cuando se fertirrigadas con 100% de efluente doméstico.

Abstract In this study, we evaluated the effects of fertigation with domestic sewage effluent and different substrates on the growth of Caraíba seedlings (Tabebuia aurea Benth). The experiment was accomplished in a greenhouse in Mossoró, RN. Five irrigation solutions (100% of water supply - WS, 100% of domestic sewage effluent - DS and dilutions of 75% DS + 25% WS, 50% DS + 50% WS e 25% DS + 75% WS) were tested and two substrates (75% soil + 25% bovine manure and 75% soil + 25% coconut fiber) using completely randomized design in subdivided plots with three replicates per treatment. Growth and development parameters were measured at 30, 60, 90, and 150 days after cultivation. The variables shoots height, collar diameter, height/diameter ratio, dry matter of root, shoots and total (root and shoots), shoots/root ratio, Dickson quality index, and nutritional evaluation of nitrogen, phosphorus, potassium and calcium were determinate. We verified that the use of domestic sewage increased growth and quality of caraíba seedlings, besides promoting nutrient accumulation in the plants grown in substrate of bovine manure plus soil with 100% application of domestic sewage in the fertigation.

Resumo O objetivo do presente trabalho foi avaliar parâmetros de qualidade de cubos de maçã Royal Gala durante o processo de desidratação osmótica (DO). As condições de operação da DO investigadas foram: o agente osmótico, a pressão e a temperatura. A atividade de água do produto foi influenciada principalmente pelo agente osmótico, sendo menor após DO com soluções de sorbitol do que de sacarose. Alterações de cor aumentaram com o incremento da temperatura e foram maiores nas experiências a vácuo do que à pressão atmosférica. Em geral, DOs a 25 °C e à pressão atmosférica são recomendadas para a conservação do teor em fenóis totais (TFT) e da atividade antioxidante (AA) dos cubos de maçã durante o processo. O modelo de Peleg permitiu o melhor ajuste dos dados experimentais de TFT e AA.

Abstract The present work aimed to evaluate quality parameters of ‘Royal Gala’ apple cubes during osmotic dehydration (OD). We investigated the following OD conditions: osmotic agent, pressure, and temperature. The osmotic agent, being lower after OD with sorbitol than sucrose solutions, mainly influenced the water activity of the product. The color changes increased with increased temperature and were higher in vacuum experiments than at atmospheric pressure. In general, we recommend OD at 25 °C and atmospheric pressure for the preservation of the total phenolic content (TPC) and antioxidant activity (AA) of apple cubes during the process. Peleg’s model was found to provide the best fit of TPC and AA data.

RESUMO O uso do percolado de aterro sanitário (PATS) na produção de biomassa para fins energético e biocombustível é uma alternativa que minimiza a degradação ambiental. Neste contexto, objetivou-se neste trabalho, analisar o efeito da aplicação de distintas proporções de percolado de aterros sanitários no cultivo de girassol (Helianthus annuus L.). O experimento foi conduzido com delineamento em blocos casualizados, com cinco tratamentos T1 - 100 % de água da rede de abastecimento - AA (Testemunha); T2 - 80 % de AA e 20 % de PATS; T3 - 60 % de AA e 40 % de PATS; T4 - 40 % de AA e 60 % de PATS; e, T5 - 20 % de AA e 80 % de PATS, e quatro repetições, totalizando 20 parcelas experimentais. O girassol foi cultivado em ARGISSOLO Vermelho - Amarelo eutrófico, durante 81 dias em Mossoró/RN. Durante o ciclo do girassol foram determinadas as características vegetativas altura de planta (AP), número de folhas (NF), diâmetro do caule (DCaule) e do capítulo (DCapítulo). Comprovou-se que para todas as variáveis estudadas houve diferença estatística entre os tratamentos. Em geral, o tratamento 60 % de AA e 40 % de PATS apresentou melhor desempenho com relação às características vegetativas do girassol.

ABSTRACT The use of landfill leachate (LL) to produce biomass for energy and biofuel purposes is an alternative that minimizes environmental degradation. In this context, the objective of this work was to evaluate the effect of using different rates of LL in the fertigation of sunflower (Helianthus annuus L.) crops. The experiment was conducted in a randomized block design with five treatments and four replications-20 experimental plots. The treatments consisted of control with 100% water from the water supply (WWS) (T1); 80% WWS + 20% LL (T2); 60% WWS + 40% LL (T3); 40% WWS + 60% LL (T4); and 20% WWS + 80% LL (T5). The sunflower crops were grown in a eutrophic Red-Yellow Argisol for 81 days, in Mossoró RN, Brazil. The plant characteristics evaluated-plant height, number of leaves, steam diameter and capitulum diameter-was determined. All variables evaluated presented statistical differences between treatments. In general, plants in the treatment 60% WWS + 40% LL presented better performance regarding the characteristics evaluated.

SUMMARY Introduction: cutaneous melanoma is considered one of the most aggressive cutaneous neoplasms with a big metastatic potential. Patterns of involvement vary according to the environmental risk factors and genetic characteristics of a population. Objectives: characterize the epidemiological profile and describe histopathological data of patients diagnosed with cutaneous melanoma by pathological reports of the Pathology Laboratory of the Santa Maria's Federal University. Methods: retrospective analytical study using described data in pathology reports from January 2013 to June 2015. Results: a total of 49 cases were analyzed, the majority has between 70-79 years old (28,6%) and were women (59%). The LMM predominated (36,7%) and 45% of the cases affected the head and neck. The majority of the cases were in situ (32,7%), the main presentation in females. Conclusions: this study showed a different epidemiology patterns from those previously described in national literature. There were a greater number of cases of LMM, which led to a biggest prevalence of older age groups and head and neck lesions. Several times, the classification of the patients' phototype was not described by the physician who performed the procedure. This study did not use the patients' records, so there was relevant information loss.

RESUMEN Introducción: melanoma cutáneo es considerado una de las neoplasias cutáneas más agresivos con gran potencial metastásico. Los patrones de participación varían de acuerdo con los factores de riesgo ambientales y las características genéticas de una población. Objetivos: caracterizar el perfil epidemiológico y describir los datos histopatológicos de los pacientes diagnosticados con melanoma cutáneo, por informes patológicos del Laboratorio de Patología de la Universidad Federal de Santa María. Materiales y Métodos: estudio analítico retrospectivo utilizando los datos descritos en los informes de patología desde Enero de 2013 a Junio de 2015. Resultados: un total de 49 casos fueron analizados, la mayoría entre 70-79 años (28,6%) y mujeres (59%). Predominó el lentigo maligno melanoma (36,7%) y 45% de los casos afectaron la cabeza y el cuello. La mayoría de los casos fueron in situ (32,7%), la presentación principal en mujeres. Conclusiones: este estudio mostró patrones de epidemiología diferentes a los descritos previamente en otros estudios brasileños. Hubo un mayor número de casos de lentigo maligno melanoma, lo que condujo a una mayor prevalencia de grupos de mayor edad y lesiones de cabeza y cuello.

ABSTRACT The CO2 emission from the soil surface, commonly referred to as soil CO2 efflux (ECO2) or soil respiration, is the sum of processes that include root respiration and microbial activity. Measuring this evolution is important to establish sustainable land use models and to estimate global fluxes of carbon, which affect climate change. Despite its importance, few measurements have been made in areas of the semiarid Brazilian Northeast region, and most of them were made using the alkali absorption method (AA), which can underestimate ECO2. Measurements using AA were compared to measurements using the infrared gas analyzer method (IRGA) over ten months (in rainy and dry seasons), during the day and night, in areas of Caatinga (xeric shrubland and thorn forest) and pasture in the Agreste region of the state of Pernambuco. The ECO2 measurements from AA varied little from night to day and throughout the year or in the rainy and dry seasons. However, those obtained from IRGA were higher in the rainy than in the dry season, but also without significant differences from day to night. The values of both methods were similar in the dry season, but in the rainy season they were higher with the IRGA. Therefore, AA seems to have little sensitivity to seasonal variations, in contrast with measurements from the IRGA, and it may underestimate soil ECO2 when it attains higher values. This result indicates that some of the soil ECO2 values determined in areas of the Brazilian semiarid region, and consequently annual C losses, may have been underestimated.

RESUMO A couve-flor e o repolho são plantas que necessitam de elevados aportes de nutrientes em curtos períodos de tempo; contudo, o uso intensivo de fertilizantes inorgânicos pode causar o desequilíbrio nutricional destas plantas e influenciar a qualidade do produto final. Neste estudo avaliou-se a composição química e a produtividade da couve-flor e do repolho cultivados sobre os resíduos de diferentes plantas de coberturas do solo em sistema plantio direto, no município de Uberaba-MG. Com delineamento de blocos ao acaso em esquema fatorial, utilizaram-se quatro plantas de coberturas (crotalária juncea, braquiária, milheto e pousio) e duas culturas (couve-flor e repolho), com quatro repetições, em parcelas de 20 m2. Após a colheita, as plantas foram levadas ao laboratório para avaliações da umidade, cinzas, lipídeos (LIP), fibra bruta (FB), proteínas (PTN), carboidratos (CHO), sólidos solúveis totais (SST), acidez total titulável (ATT), pH e ácido ascórbico (AA), massa fresca da cabeça (MFC), massa seca da cabeça (MSC) e produtividade (Prod). As plantas de couve-flor cultivada sobre os resíduos de crotalária juncea apresentaram maiores teores de LIP, PTN, CHO, SST e ATT, enquanto que nos resíduos de braquiária e milheto, os teores de AA foram maiores quando comparados a crotalária. As plantas de repolho apresentaram valores significativamente maiores na sua parte aérea de CHO, ATT e AA quando cultivadas sobre os resíduos de braquiária, enquanto que para a PTN se destacou com o plantio sobre os resíduos da crotalária juncea. O cultivo da couve-flor e repolho sobre os resíduos de plantas de cobertura alteraram positivamente a maioria dos atributos químicos das culturas, quando comparados à área deixada em pousio, sendo que os melhores resultados de produtividade e AA ocorreram quando as culturas foram cultivadas sobre resíduos de braquiária.

ABSTRACT Cauliflower and cabbage require high amounts of nutrients in short periods of time; however, the intensive use of inorganic fertilizers can cause nutritional imbalances in these crops and reduce the quality of the final product. This study evaluated the chemical composition and yield of no-till cauliflower and cabbage grown on residues of various cover crops in Uberaba, Minas Gerais State, Brazil. The experimental design was randomized blocks with four cover crops (sunn hemp, brachiaria, pearl millet and fallow) and two main crops (cauliflower and cabbage). The treatments were evaluated on plots of 20 m2 with four replications. The following traits were analyzed after harvest: moisture (MO), ash (ASH), lipid (LIP), crude fiber (CF), protein (PTN), carbohydrates (CARB), total soluble solids (TSS), total titratable acidity (TTA), pH, ascorbic acid (AA), head fresh weight (HFW), head dry weight (HDW) and yield. Cauliflower cultivated on sunn hemp residues produced high levels of LIP, PTN, CARB, TSS and TTA, whereas cauliflower cultivated on brachiaria and millet residues demonstrated high AA levels when compared to the treatment with sunn hemp residues. In the aerial part, cabbage presented significantly higher levels of CARB, TTA and AA when cultivated on brachiaria residues, whereas PTN levels were higher on sunn hemp residues. The cultivation of cauliflower and cabbage on cover crop residues affected positively most of the chemical attributes of the evaluated crops when compared to the fallow treatment, although the highest yield and AA levels were observed when the crops were cultivated on brachiaria residues.

ABSTRACT: Improved spray deposition can be attained by electrostatically charging spray droplets, which increases the attraction of droplets to plants and decreases operator exposure to pesticide and losses to the environment. However, this technique alone is not sufficient to achieve desirable penetration of the spray solution into the crop canopy; thus, air assistance can be added to the electrostatic spraying to further improve spray deposition. This study was conducted to compare different spraying technologies on spray deposition and two-spotted spider mite control in cut chrysanthemum. Treatments included in the study were: conventional TJ 8003 double flat fan nozzles, conventional TXVK-3 hollow cone nozzles, semi-stationary motorized jet launched spray with electrostatic spray system (ESS) and air assistance (AA), and semi-stationary motorized jet launched spray with AA only (no ESS). To evaluate the effect of these spraying technologies on the control of two-spotted spider mite, a control treatment was included that did not receive an acaricide application. The AA spraying technology, with or without ESS, optimized spray deposition and provided satisfactory two-spotted spider mite control up to 4 days after application.