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Abstract: In recent decades, the growing obesity epidemic in Mexico has become one of the most important public health challenges faced by the country. With support from the World Obesity Federation, we formed a working group in 2021 to identify and summarize priority actions that Mexico can take to face this epidemic. More than 1 000 health professionals joined the development and discussion process. Recommendations from previously published, high-level documents and guidelines were taken into account. In commemoration of World Obesity Day 2022, this statement is presented as input for health care professionals to develop actions to address obesity. The statement includes 10 recommendations that include population-level and individual-level actions. It emphasizes the importance of social participation, comprehensive interventions with a person- centered perspective, planetary sustainability, on improving education and communication campaigns, as well as fostering a built environment that promotes active living, and shielding prevention and control efforts from conflicts of interest. The statement calls for obesity to be treated seriously, based on scientific evidence, in a timely and comprehensive manner, employing a life-course and ethical approach that does not perpetuate weight stigma in society.

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https://doi.org/10.21149/13679

Guía de práctica clínica mexicana para el diagnóstico y tratamiento de las dislipidemias y enfermedad cardiovascular aterosclerótica
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Pavía-López, Abel A.

; Alcocer-Gamba, Marco A.

; Ruiz-Gastelum, Edith D.

; Mayorga-Butrón, José L.

; Mehta, Roopa

; Díaz-Aragón, Filiberto A.

; Aldrete-Velasco, Jorge A.

; López-Juárez, Nitzia

; Cruz-Bautista, Ivette

; Chávez-Mendoza, Adolfo

; Secchi-Nicolás, Nikos C.

; Guerrero-Martínez, Francisco J.

; Cossio-Aranda, Jorge E.

; Mendoza-Zubieta, Victoria

; Fanghänel-Salmon, Guillermo

; Valdivia-Proa, Martha

; Olmos-Domínguez, Luis

; Aguilar-Salinas, Carlos A.

; Dávila-Maldonado, Luis

; Vázquez-Rangel, Armando

; Pavia-Aubry, Vanina

; Nava-Hernández, María de los A.

; Hinojosa-Becerril, Carlos A.

; Anda-Garay, Juan C.

; Ríos-Ibarra, Manuel O. de los

; Berni-Betancourt, Ana C.

; López-Cuellar, Julio

; Araiza-Garaygordobil, Diego

; Rivera-Reyes, Romina

; Borrayo-Sánchez, Gabriela

; Tapia-Hernández, Mónica

; Cano-Nigenda, Claudia V.

; Guerra-López, Arturo

; Elías-López, Josué

; Figueroa-Morales, Marco A.

; Montaño-Velázquez, Bertha B.

; Velasco-Hidalgo, Liliana

; Rodríguez-Lozano, Ana L.

; Pimentel-Hernández, Claudia

; Baquero-Hoyos, María M.

; Romero-Moreno, Felipe

; Rodríguez-Vega, Mario

Archivos de cardiología de México

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2022, Volume 92 Supl. 1 Páginas 1 - 62

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

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Abstract Background: Cardiovascular diseases are the leading cause of mortality worldwide and Mexico is no exception. The epidemiological data obtained in 1990 showed that cardiovascular diseases represented 19.8% of all causes of death in our country. This figure increased significantly to 25.5% for 2015. Some national surveys suggest that more than 60% of the adult population has at least one risk factor for cardiovascular disease (obesity or overweight, hypertension, smoking, diabetes, dyslipidemias). On the other hand, data from the Pan American Health Organization have linked the process of atherosclerosis as the first cause of premature death, significantly reducing life expectancy, which has enormous social repercussions. Objective: This document constitutes the Clinical Practice Guide (CPG) prepared at the initiative of the Mexican Society of Cardiology in collaboration with the Mexican Society of Nutrition and Endocrinology, AC, National Association of Cardiologists of Mexico, AC, Mexican Association for the Prevention of Atherosclerosis and its Complications, AC, National Normative Committee of General Medicine, AC, National College of Geriatric Medicine, AC, College of Internal Medicine of Mexico, AC, Mexican Society of Angiology and Vascular and Endovenous Surgery, AC, Mexican Institute of Research Nephrological, AC and the Mexican Academy of Neurology, A.C.; with the methodological support of the Ibero-American Agency for the Development and Evaluation of Health Technologies, in order to establish recommendations based on the best available evidence and agreed upon by an interdisciplinary group of experts. The objective of this document is to provide evidence-based recommendations to help decision makers in the diagnosis and treatment of dyslipidemias in our country. Material and methods: This document complies with international quality standards, such as those described by the Institute of Medicine of the USA, the Institute of Clinical Excellence of Great Britain, the Scottish Intercollegiate Guideline Network and the Guidelines International Network. A multidisciplinary group of clinical experts and methodologists with experience in systematic reviews of the literature and the development of clinical practice guidelines was formed. A scope document was agreed upon, relevant clinical questions were established, the best available evidence critically evaluated in systematic literature reviews was exhaustively identified, and clinical recommendations were developed. The modified Delphi Panel methodology was used to achieve an adequate level of consensus in each of the recommendations contained in this CPG. Results: 23 clinical questions were agreed upon which gave rise to their respective clinical recommendations. Conclusions: We consider that this document contributes to better clinical decision-making and becomes a point of reference for clinicians and patients in the management of dyslipidemias and this contributes to reducing the morbidity and mortality derived from atherosclerotic cardiovascular events in our country.

https://doi.org/10.24875/acm.m22000081 1458 downloads

Memory elicitation, T-cell response and antibody production: an independent study of an inactivated entire virus vaccine (Coronavac)
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SOUZA-SILVA, GUILHERME ANTONIO DE

; AQUINO, RODRIGO CESAR A. DE

; SOUSA, GEORON F. DE

; BARROS, BÁRBARA RAFAELA S.

; LIMA, MARÍLLIA RAPHAELLA C.F. DE

; CRUZ, LEONARDO C.O.

; MARCOS, BIANCA F. SÃO

; SILVA, ANNA JÉSSICA D.

; TALES, APARECIDA VIRGÍNIA S.

; DINIZ, MADI V.

; LIMA, MÔNICA MARIA C.

; SÁ, IGOR W.A. DE

; RODRIGUES, FÁBIO AUGUSTO C.

; SOUZA, EDSON B. DE

; NASCIMENTO, ARIONE V. DO

; VIEIRA, AMANDA M.

; CARVALHO, BRUNO M. DE

; CAMPELO JÚNIOR, EVÔNIO B.

; FREITAS, ANTONIO CARLOS DE

; MELO, CRISTIANE M.L. DE

Anais da Academia Brasileira de Ciências

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2022, Volume 94 Nº 3 elocation e20211590

Resumo: En | Texto: En | PDF: En

Abstract Health professionals working to mitigate the COVID-19 pandemic are one of the main risk groups for the disease, being prioritized for vaccination. Considering this, the aim of this study was to analyze the immune response of these professionals immunized with CoronaVac in the first and second doses. Blood samples were collected after the first and second doses of the vaccine (CoronaVac) and used to investigate hematological and biochemical parameters, analysis of immunoglobulin production, cytokines, and gene expression profile, as well as the identification of subsets of immune cells. Post-first dose immunological phenotypic memory (CD27+) profiles (T CD4+, TCD8+ and CD19+) showed a significant increase, as did Monocyte APCs (CD80+HLA-DR+) in relation to the second dose. The cytokines IL-2, IL-6 and IFN-° showed increased values in relation to the other analyzed cytokines. The Th2/Th17 profile in the second dose was characterized by gene expression analysis. The production of IgM and IgG after vaccination showed statistically significant values in the comparison between doses. CoronaVac showed activation of APCs monocytes, memory response of T and B lymphocytes, with immunoglobulins production. This set of responses is characterized by the Th2/Th17 immunological profile.

https://doi.org/10.1590/0001-3765202220211590

Genetic parameters for performance and carcass traits in a paternal 1 lineage of broiler
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CRUZ, VALDECY A.R.

; GRUPIONI, NATALIA V.

; MENDONÇA, GABRIELA G.

; VENTURINI, GUILHERME C.

; LEDUR, MONICA C.

; PEIXOTO, JANE O.

; MUNARI, DANISIO P.

Anais da Academia Brasileira de Ciências

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2020, Volume 92 elocation e20180697

Resumo: En | Texto: En | PDF: En

Abstract The objective of this study was to estimate variance components for performance and carcass traits in a paternal broiler line. The (co)variance components were estimated by the restricted maximum likelihood method applied to the animal model, including the fixed effect of group (sex and hatch) and additive genetic and residual as random effects. Estimated heritability for performance traits ranged from 0.09 to 0.42. The genetic correlations between traits ranged from -0.50 to 0.97. The heritability estimates of feed intake, weight gain, and feed conversion from 35 to 41 days of age were of low magnitude. The genetic correlations among them were favorable to genetic selection. These results suggest that moderate genetic gain can be obtained to the feed intake and weight gain when the selection criterion is the body weight and prime cuts traits. The feed conversion that had low heritability estimation and low genetic correlation with the body weight and prime cut traits needs to pay greater attention due to the economic importance in the high-meat production lineage breeding programs.

https://doi.org/10.1590/0001-3765202020180697 578 downloads

Cheese whey exploitation in Brazil: a questionnaire survey
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TRINDADE, Monika B.

; SOARES, Bruna C. V.

; SCUDINO, Hugo

; GUIMARÃES, Jonas T.

; ESMERINO, Erick A.

; FREITAS, Mônica Q.

; PIMENTEL, Tatiana C.

; SILVA, Marcia Cristina

; SOUZA, Simone L. Q.

; ALMADA, Rafael B.

; CRUZ, Adriano G.

Food Science and Technology

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Set 2019, Volume 39 Nº 3 Páginas 788 - 791

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to carry out a diagnosis of the cheese whey exploitation by the Brazilian dairy industry using a questionnaire survey. The dairy industries (n=100) were mainly from Southeast (55%) and South (25%) regions and supervised by the Federal Inspection System (80%). Most of them produced (67%) and processed (60%) sweet cheese whey, using it in whey dairy beverages (60%), Ricotta (20%), whey concentrate (15%), and milk blends (5%), which were resold for supermarkets (53%) or industries (20%). However, 27% of the industries discard whey in the effluent treatment system or use as animal feed, suggesting a market for using this by-product.

https://doi.org/10.1590/fst.07419 1274 downloads

IV Brazilian Consensus on Rhinitis - an update on allergic rhinitis,
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Sakano, Eulalia

; Sarinho, Emanuel S.C.

; Cruz, Alvaro A.

; Pastorino, Antonio C.

; Tamashiro, Edwin

; Kuschnir, Fábio

; Castro, Fábio F.M.

; Romano, Fabrizio R.

; Wandalsen, Gustavo F.

; Chong-Neto, Herberto J.

; Mello Jr., João F. de

; Silva, Luciana R.

; Rizzo, Maria Cândida

; Miyake, Mônica A.M.

; Rosário Filho, Nelson A.

; Rubini, Norma de Paula M.

; Mion, Olavo

; Camargos, Paulo A.

; Roithmann, Renato

; Godinho, Ricardo N.

; Pignatari, Shirley Shizue N.

; Sih, Tania

; Anselmo-Lima, Wilma T.

; Solé, Dirceu

Brazilian Journal of Otorhinolaryngology

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Jan 2018, Volume 84 Nº 1 Páginas 3 - 14

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução As diretrizes sobre rinite alergica visam atualizar os conhecimentos sobre a doença e os cuidados para com esses pacientes. A iniciativa designada "Rinite Alergica e seu Impacto na Asma", cujo relatorio inicial foi publicado em 2001 e atualizada em 2008 e 2010, tem sido muito bem sucedida na disseminaçao de informaçoes e evidencias, bem como na formulaçao da classificaçao de gravidade e proposta de sistematizaçao do tratamento. Entretanto, visando a participaçao de outros profissionais medicos no atendimento da rinite alergica, e importante o desenvolvimento de algoritmos que indiquem com precisao o que deve e pode ser feito regionalmente. Objetivo Atualizar o III Consenso Brasileiro sobre Rinites-2012, com elaboraçao de algoritmo para conduta da rinite alergica. Método Foram convidados 24 especialistas indicados pelas Associaçao Brasileira de Alergia e Imunologia, Associaçao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial e Sociedade Brasileira de Pediatria para atualizaçao do documento de 2012. Resultados A atualizaçao do ultimo Consenso Brasileiro sobre Rinites, incorporou e adaptou para a realidade brasileira as informaçoes relevantes publicadas em todos os documentos da Iniciativa "Rinite Alergica e seu Impacto na Asma", trazendo novos conceitos como a rinite alergica local, novos medicamentos e metodos de avaliaçao de tratamento. Conclusão Proposto um fluxograma de tratamento para a rinite alergica.

Abstract Introduction The guidelines on allergic rhinitis aim to update knowledge about the disease and care for affected patients. The initiative called "Allergic Rhinitis and its Impact on Asthma", initially published in 2001 and updated in 2008 and 2010, has been very successful in disseminating information and evidence, as well as providing a classification of severity and proposing a systemized treatment protocol. In order to include the participation of other medical professionals in the treatment of allergic rhinitis, it is important to develop algorithms that accurately indicate what should and can be done regionally. Objective To update the III Brazilian Consensus on Rhinitis - 2012, with the creation of an algorithm for allergic rhinitis management. Methods We invited 24 experts nominated by the Brazilian Association of Allergy and Immunology, Brazilian Association of Otorhinolaryngology and Head and Neck Surgery and Brazilian Society of Pediatrics to update the 2012 document. Results The update of the last Brazilian Consensus on Rhinitis incorporated and adapted the relevant information published in all "Allergic Rhinitis and its Impact on Asthma" Initiative documents to the Brazilian scenario, bringing new concepts such as local allergic rhinitis, new drugs and treatment evaluation methods. Conclusion A flowchart for allergic rhinitis treatment has been proposed.

https://doi.org/10.1016/j.bjorl.2017.10.006 26131 downloads

Obtención de partículas de Ti O2 por sol-gel, asistido con ultrasonido para aplicaciones fotocatalíticas
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Martínez Rojas, Vanessa C.

; Matejova, Lenka

; López Milla, Alcides

; Cruz, Gerardo J. F.

; Solís Veliz, José L.

; Gómez León, Mónica M.

Revista de la Sociedad Química del Perú

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Jul 2015, Volume 81 Nº 3 Páginas 201 - 211

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Synthesis of TiO2 particles was made by sol-gel technique assisted of ultrasonic radiation from an alcoholic solution of titanium isopropoxide. Then was subjected to a heat treatment in air at 350 °C for 1 h. X-ray diffraction and transmission electron microscopy confirmed that the size of the crystalline domains is between 10 and 37 nm. Infrared spectroscopy study confirms the presence of -OH groups on the surface of TiO2. Modification of the morphology and surface area, due to the influence of exposure time to the ultrasonic radiation, is evidenced by studies of SEM and BET respectively. Properties of TiO2 obtained were studied by monitoring the degradation of solutions of methyl orange in the presence of UV-A radiation. It was observed that larger the ultrasonic radiation exposure during the TiO2 synthesis larger the constant velocity for the photocatalytic reaction for the methyl orange.

La síntesis de las partículas de TiO2 se realizó mediante la técnica sol-gel asistida con radiación ultrasónica a partir de una solución alcohólica de isopropóxido de titanio. Luego se sometió a un tratamiento térmico en atmósfera de aire a 350 ºC por 1 h. Difracción de rayos X y microscopía electrónica de transmisión confirmaron que el tamaño de los dominios cristalinos se encuentran entre 10 y 37 nm. El estudio de espectroscopía infrarroja confirma la presencia de grupos -OH en la superficie del TiO2. La modificación de la morfología y el área superficial, debido a la influencia del tiempo de exposición a la radiación ultrasónica, se evidencia con los estudios de microscopía electrónica de barrido y BET, respectivamente. Las propiedades del TiO2 obtenido se estudiaron monitoreando la degradación de soluciones de anaranjado de metilo en presencia de radiación UV-A. Se observó que a mayor exposición de radiación ultrasónica durante la síntesis de las muestras de TiO2, mayor fue la constante de velocidad para la reacción de fotocatálisis del anaranjado de metilo.

Confort térmico de techos verdes con Cissus verticillata (Vitaceae) en vivendas rurales tropicales
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Beltrán-Melgarejo, Abraham

; Vargas-Mendoza, Mónica de la C.

; Pérez-Vázquez, Arturo

; García-Albarado, J. Cruz

Revista mexicana de ciencias agrícolas

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Nov 2014, Volume 5 Nº spe9 Páginas 1551 - 1560

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Green roofs have taken rise because of the several benefits they provide, including thermal mitigation of buildings, and improving thermal comfort (TC). Although it is a desirable technology in warm, tropical areas, is required to lighten its conventional design, in order to adapt it to the tropical rural dwellings. This research was conducted in Veracruz, Mexico, for evaluating the TC provided by a prototype green roof based on the use of pergolas and Creeper Cissus verticillata (Vitaceae). The temperature under the roof sheet of rural households with and without green roof was compared. The TC of the rooms was measured using subjective vote (SV), the average predicted vote (APV), and the proportion of people uncomfortable (PPU), obtained from a group of evaluators resident and another visitor, who also rated their degree acceptance of this technology. The average temperature in the room with green roof was up to 4.5 °C lower (p < 0.05) than in rooms without green roof. The SV, APV, and PPU were higher (p< 0.01, p< 0.01 and p< 0.0001, respectively) in rooms without green roof, indicating a lower TC therein. Acceptance of the visiting group was significantly higher than that of the resident (p< 0.0001). It is concluded that by using green roofs as proposed is reached greater TC in tropical rural homes.

Resumen Los techos verdes han tomado auge debido a los múltiples beneficios que brindan, entre ellos la mitigación térmica de los edificios, y la mejora del confort térmico (CT). Aunque es una tecnología deseable en zonas cálidas y tropicales, se requiere aligerar su diseño convencional, a fin de adaptarlos a la vivienda rural tropical. La investigación se realizó en Veracruz, México, para evaluar el CT brindado por un prototipo de techo verde basado en el uso de pérgolas y de la enredadera Cissus verticillata (Vitaceae). Se comparó la temperatura bajo la lámina del techo de habitaciones de viviendas rurales con y sin techo verde. El CT de las habitaciones fue medido por el voto subjetivo (VS), el voto medio predicho (VMP), y la proporción de personas a disgusto (PPD), obtenidos de un grupo de evaluadores residente y otro visitante, quienes también calificaron su grado de aceptación de esta tecnología. La temperatura promedio bajo la lámina de las habitaciones con techo verde fue hasta 4.5 °C menor (p< 0.05) que en las habitaciones sin techo verde. El VS, VMP, y la PPD fueron mayores (p< 0.01, p< 0.01, y p< 0.0001, respectivamente) en las habitaciones sin techo verde, indicando un menor CT en éstas. La aceptación del grupo visitante fue significativamente mayor que la del residente (p< 0.0001). Se concluye que mediante el uso de techos verdes como el propuesto se alcanza un mayor CT en las viviendas rurales tropicales.

https://doi.org/10.29312/remexca.v0i9.1047 915 downloads

The semisynthetic landscape of aphidicolin: inspiration towards leishmanicidal compounds
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Santos, Gabriela B.

; Almeida, Marília O.

; Cardoso, Iara A.

; Manfrim, Viviane

; Chagas, Fernanda O.

; Toledo, Juliano S.

; Pinzan, Camila C.

; Araujo, Alexandre Suman de

; Cruz, Angela K.

; Pupo, Monica T.

; Emery, Flavio S.

Journal of the Brazilian Chemical Society

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Out 2014, Volume 25 Nº 10 Páginas 1885 - 1899

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Recentes estudos demonstraram que afidicolina, metabólito secundário do fungo endofítico Nigrospora sphaerica, apresenta alta atividade contra o protozoário Leishmania major. Apesar do promissor potencial leishmanicida, a afidicolina apresenta propriedades físico-químicas e perfil farmacocinético inadequado para terapêutica. Neste sentido, uma revisão da literatura apresenta as limitadas modificações para este terpeno e ainda traz informações sobre as propriedades moleculares dos compostos já descritos e sua correlação com compostos leishmanicidas. Essa revisão forneceu uma análise racional para o desenvolvimento do derivado oxima. Uma série de derivados da afidicolina bem como o análogo oxima foram sintetizados para avaliação preliminar dos requisitos estruturais para atividade leishmanicida da afidicolina e seus derivados semi-sintéticos. Oito compostos foram sintetizados e testados contra diferentes espécies de Leishmania. A avaliação preliminar demonstrou alta atividade leishmanicida da afidicolina enquanto que o derivado oxima apresenta moderada seletividade contra a espécie L. braziliensis, endêmica em diversos países da América do Sul. Nenhum dos compostos apresentou citotoxicidade contra células de mamíferos.

Recent studies have shown that aphidicolin, a secondary metabolite of the endophytic fungus Nigrospora sphaerica, has high activity against the protozoan Leishmania major. Despite its promising leishmanicidal potential, aphidicolin presents a therapeutically unsuitable physico-chemical and pharmacokinetic profile. In this sense, a review of the literature shows the limited types of modification for this terpene. In addition, it gives an idea about the molecular properties of the compounds produced and which were correlated to leishmanicidal derivatives. This analysis provided us a rationale for the development of an oxime derivative. We synthesized the oxime-aphidicolin and a series of derivatives for a preliminary evaluation of the structural requirements for the leishmanicidal activity of aphidicolin and its semisynthetic derivatives. Eight compounds have been synthesized and tested against different species of the Leishmania protozoa. The preliminary evaluation demonstrated high leishmanicidal activity for aphidicolin, while the oxime derivative shows moderate selectivity for the L. braziliensis species, which is commonly found in several South American countries. None of the compounds showed cytotoxicity against mammalian cells.

https://doi.org/10.5935/0103-5053.20140162 1627 downloads

10.

Parámetros poblacionales de Tetranychus merganser Boudreaux (Acari: Tetranychidae) en papayo (Carica papaya L.) a diferentes temperaturas
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Reyes-Pérez, Noel

; Villanueva-Jiménez, Juan A.

; de la Cruz Vargas-Mendoza, Mónica

; Cabrera-Mireles, Héctor

; Otero-Colina, Gabriel

Agrociencia

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Mar 2013, Volume 47 Nº 2 Páginas 147 - 157

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Tetranychus merganser is a mite species that causes greater economic damage in the papaya (Carica papaya) production area in the state of Veracruz, Mexico. Therefore, it was necessary to study their biology in order to make better decisions in their management. We obtained a colony of mites from a female collected in the municipality of Manlio F. Altamirano, and expanded their population on bean leaves (Phaseolus vulgaris) under greenhouse conditions. The objective was to evaluate the influence of temperature on the population parameters of this species and the duration of their developmental stages. For this purpose, we established cohorts starting with eggs, and exposed them to the following conditions: constant temperatures (19, 23, 27, 31, 33 and 35 °C); 60±2 % relative humidity, photoperiod of 14:10 h light:dark, and fed with papaya leaf discs. The duration of the life cycle of T. merganser decreased from 52.3 to 12.9 d with the increase of temperature. The net reproductive rate (R) was 37.40, 62.38, 43.98, 10.47 and 2.32 for 19, 23, 27, 31 and 33 °C; at 35 °C, the cohort was not viable. The intrinsic rate of population increase (r m) was 0.08, 0.19, 0.21, 0.18 and 0.12 at the temperatures recorded. Optimal development occurred between 23 and 27 C. Although papaya is not its best host compared to more favorable population parameters obtained by other authors in beans, T. merganser can behave like a pest in papaya under the environmental conditions prevailing in the area.

El ácaro Tetranychus merganser es una de las especies que causa mayor daño económico en la zona productora de papayo (Carica papaya) del estado de Veracruz, México. Por tanto, se requiere conocer aspectos de su biología para tomar mejores decisiones de su manejo. Se obtuvo una colonia de ácaros a partir de una hembra recolectada en el municipio de Manlio F. Altamirano, y se incrementó la población en invernadero sobre hojas de frijol (Phaseolus vulgaris). El objetivo fue evaluar la influencia de la temperatura en los parámetros poblacionales de esta especie y sobre la duración de sus fases de desarrollo. Para ello se iniciaron cohortes desde huevecillos y expuestas a las siguientes condiciones: temperaturas constantes (19, 23, 27, 31, 33 y 35 °C); 60±2 % de humedad relativa; fotoperiodo de 14:10 h luz:oscuridad y alimentación en discos de hojas de papaya. La duración del ciclo de vida de T. merganser disminuyó de 52.3 hasta 12.9 d con el aumento de la temperatura. La tasa neta reproductiva (Ro) fue 37.40, 62.38, 43.98, 10.47 y 2.32 para 19, 23, 27, 31 y 33° C; a 35 °C la cohorte no fue viable. La tasa intrínseca de crecimiento poblacional (r m) fue 0.08, 0.19, 0.21, 0.18 y 0.12 a las temperaturas anotadas. El desarrollo óptimo ocurrió entre 23 y 27 °C. Aunque el papayo no es su mejor hospedero comparado con parámetros poblacionales más favorables obtenidos por otros autores en frijol, T. merganser puede comportarse como plaga en papayo en las condiciones ambientales predominantes en la zona.

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11.

Bioactive extracts and chemical constituents of two endophytic strains of Fusarium oxysporum
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Nascimento, Andréa M. do

; Conti, Raphael

; Turatti, Izabel C. C.

; Cavalcanti, Bruno C.

; Costa-Lotufo, Letícia V.

; Pessoa, Cláudia

; Moraes, Manoel O. de

; Manfrim, Viviane

; Toledo, Juliano S.

; Cruz, Angela K.

; Pupo, Mônica T.

Revista Brasileira de Farmacognosia

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Dez 2012, Volume 22 Nº 6 Páginas 1276 - 1281

Resumo: En | Texto: En | PDF: En

Ethyl acetate extracts of cultures grown in liquid Czapek and on solid rice media of the fungal endophyte Fusarium oxysporum SS46 isolated from the medicinal plant Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, exhibited considerable cytotoxic activity when tested in vitro against human cancer cells. Chromatographic separation yielded anhydrofusarubin (1) and beauvericin (2) that were identified based on their ¹H and 13C NMR data. Compounds 1 and 2 showed the strongest cytotoxic activity against different cancer cell lines. Compound 2 also showed promising activity against Leishmania braziliensis. Hexanic extract of F. oxysporum SS50 grown on solid rice media also afforded a mixture of compounds that displayed cytotoxic activity against different cancer cell lines. Chemical analysis of the mixture of compounds, investigated by gas chromatography-mass spectrometry (GC-MS), showed that there was a predominance of methyl esters of fatty acids and alkanes.

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12.

Perdas causadas pela ferrugem-asiática em cultivares de soja semeadas em diferentes épocas, no Oeste da Bahia
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Cruz, Thyane V. da

; Peixoto, Clovis P.

; Martins, Mônica C.

; Laranjeira, Francisco F.

; Lopes, Pedro V. Lima

; Andrade, Newton S.

; Ledo, Carlos A. da Silva

Tropical Plant Pathology

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Ago 2012, Volume 37 Nº 4 Páginas 255 - 265

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Este trabalho teve como objetivo quantificar os danos causados pela ferrugem-asiática em três cultivares de soja, semeadas em diferentes épocas, na região Oeste da Bahia. Os experimentos foram instalados no município de São Desidério, BA, nas safras 2007/2008 e 2008/2009. O delineamento experimental foi em blocos casualizados com quatro repetições, no esquema de parcelas subdivididas no espaço. A parcela foi representada pelos tratamentos de controle da ferrugem (com ou sem aplicação de fungicida) e as subparcelas foram representadas pelas cultivares (Monsoy 8411, BRS Corisco e BRS Barreiras). Avaliou-se a severidade da ferrugem para o cálculo da área abaixo da curva de progresso da doença padronizada (AACPDp), o número de folhas ao longo do ciclo e a produtividade de grãos. O modelo logístico foi o que melhor se ajustou aos dados da severidade. A variação temporal do número de folhas foi ajustada pela função polinomial exponencial Ln (y) = a + bx1,5 + cx0,5. As médias da AACPDp e a da produtividade foram comparadas pelo teste de Tukey a 5% de probabilidade. Os danos causados pela ferrugem-asiática da soja na região foram potencializados na época de semeadura tardia, ocorrendo desfolha antecipada e redução na produtividade de grãos.

The objective of this work was to quantify the yield loss caused by Asian soybean rust in three cultivars sown in different periods in the western region of Bahia. The experiments were installed in São Desidério, BA, in the growing seasons 2007/2008 and 2008/2009. The experimental design was carried out in random blocks with four replicates and subdivided plot scheme in time. The plot was represented by the rust control treatments (with and without chemical control) and the subplots represented by cultivars (Monsoy 8411, BRS Corisco and BRS Barreiras). The severity, number of leaves throughout the cycle and yield were evaluated. The logistic model was the one that better fitted the severity data whereas the polynominal exponential function Ln (y) = a + bx1, 5 + cx0,5 fitted the temporal variation of number of leaves better. The means of the area under the disease progress curve and yield were compared by Tukey test. Yield loss increased during later sowing periods due to greater inoculum pressure hindering disease control and decreasing grain yield.

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13.

Desenvolvimento do Instrumento de Avaliação Neuropsicológica Breve Infantil NEUPSILIN-INF
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Salles, Jerusa Fumagalli de

; Fonseca, Rochele Paz

; Cruz-Rodrigues, Camila

; Mello, Claudia B.

; Barbosa, Thais

; Miranda, Mônica C.

Psico-USF

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Dez 2011, Volume 16 Nº 3 Páginas 297 - 305

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

O objetivo deste estudo é apresentar o processo de desenvolvimento e validação de conteúdo do Instrumento de Avaliação Neuropsicológica Breve Infantil NEUPSILIN-INF, que avalia, de modo breve, componentes de oito funções neuropsicológicas em crianças em idade escolar: orientação, atenção, percepção visual, memória, habilidades aritméticas, linguagem, habilidades visuoconstrutivas e funções executivas. O processo envolveu: 1) análise do instrumento original NEUPSILIN e definição das funções e tarefas a serem adaptadas para avaliação neuropsicológica infantil; 2) desenvolvimento de novas tarefas consideradas fundamentais para a avaliação na infância; 3) estudo piloto 1 com a versão preliminar do instrumento; 4) análise de juízes especialistas; 5) estudos piloto 2 e 3, nova reformulação de tarefas do instrumento e elaboração de sua versão final. O instrumento apresentou adequada validade aparente e de conteúdo.

The aim of this study is to present the development process and content validation of Child Brief Neuropsychological Assessment Battery NEUPSILIN-INF, which briefly assesses the components of eight neuropsychological functions in school-aged children: orientation, attention, visual perception, memory, arithmetic abilities, language, visuoconstructive abilities and executive functions. The process comprised: 1) the analysis of the original NEUPSILIN instrument and definition of the functions and tasks to be adapted for the child neuropsychological assessment; 2) the development of new tasks considered as fundamental for the assessment in children; 3) pilot study 1 with the preliminary version of the instrument; 4) analysis by specialist judges; 5) pilot studies 2 and 3, new reformulation of the instrument's tasks and preparation of its final version. The instrument presented appropriate face and content validity.

17505 downloads Citado 6 vezes em SciELO

14.

Reeducação Postural Global: uma revisão da literatura
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Teodori, Rosana M.

; Negri, Júlia R.

; Cruz, Mônica C.

; Marques, Amélia P.

Brazilian Journal of Physical Therapy

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Jun 2011, Volume 15 Nº 3 Páginas 185 - 189

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

CONTEXTUALIZAÇÃO: O método de Reeducação Postural Global (RPG) tem sido utilizado na clínica com relatos de benefícios para a prevenção e recuperação de disfunções musculoesqueléticas. Após duas décadas de aplicação, estudos têm verificado sua eficácia no tratamento de diferentes condições clínicas e ele tem sido comparado com outros recursos fisioterapêuticos. Entretanto, são poucos os estudos voltados à comprovação dos princípios defendidos pelo autor do método, o que torna frágeis as argumentações em favor dele. OBJETIVO: Realizar, com base na literatura científica, uma análise crítica dos efeitos da intervenção fisioterapêutica utilizando o método RPG. MÉTODOS: Pesquisaram-se as bases de dados Medline, SciELO, LILACS e PeDRO, de 2000 a 2010, considerando os unitermos: RPG, alongamento global e alongamento ativo. RESULTADOS: Foram encontrados 25 estudos, sendo 13 relacionados ao método RPG e oito aos alongamentos global e ativo, além de três livros e uma tese. Após análise, 20 referências foram utilizadas. CONCLUSÕES: Parte dos estudos aponta que o método RPG é mais efetivo, enquanto outros mostram resultados similares a outros métodos de intervenção fisioterapêutica. Estudos indicam benefícios do método na melhora da força muscular respiratória, expansibilidade torácica, mobilidade toracoabdominal e da pressão respiratória máxima, além de reduzir a dor, a perda de urina em mulheres incontinentes, melhorar a flexibilidade, a atividade eletromiográfica nas disfunções temporomandibulares e a estabilidade postural em alterações ortopédicas de membros inferiores. Limitações metodológicas observadas sugerem a necessidade de maior rigor em futuras pesquisas.

BACKGROUND: The Global Postural Re-education (GPR) method has been widely used in clinical practice, with reported benefits for prevention and rehabilitation of musculoskeletal dysfunctions. In parallel with almost two decades of clinical implementation, research studies have tested and verified the effectiveness of GPR in treating different clinical conditions and have also compared this method with other physical therapy resources. However, few studies focused on the verification of the principles of mechanisms of action defended by the author of the method making the arguments in favor of the method weak. OBJECTIVE: To perform a critical systematic review of the effects of physical therapy intervention that use the GPR method. METHODS: We searched Medline, SciELO, LILACS and PeDRO, from 2000 to 2010, considering the key words: Global Postural Re-education, global and active stretching. RESULTS: We found 25 studies, 13 about GPR and 8 about global and active stretching in addition to three books and a thesis. After analysis, 20 references were included. CONCLUSIONS: Some of the studies indicated that the GPR method was more effective than other physical therapy interventions, while others demonstrated similar results of GPR when compared to other physical therapy interventions. Studies showed benefits of the GPR in improving the respiratory muscle strength, chest expansion, maximal respiratory pressure and in reducing pain, loss of urine in incontinent women, increasing flexibility, the electromyographic activity in temporomandibular disorders and postural stability in lower limb orthopedic alterations. Methodological limitations observed suggest the need for greater rigor in future research.

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15.

Neurospora crassa mat A-2 and mat A-3 proteins weakly interact in the yeast two-hybrid system and affect yeast growth
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Silva, Carla C. da

; Cruz, Rosana C.

; Bucciarelli-Rodriguez, Mônica

; Vilas-Boas, Adlane

Genetics and Molecular Biology

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2009, Volume 32 Nº 2 Páginas 354 - 361

Resumo: En | Texto: En | PDF: En

Mating-type genes control the entry into the sexual cycle, mating identity and sexual development in fungi. The mat A-2 and mat A-3 genes, present in the mat A idiomorph of the filamentous fungus Neurospora crassa, are required for post-fertilization functions but are not essential for mating identity. Their putative roles as transcription factors are based on the similarity of mat A-2 with the Podospora anserina SMR1 gene and an HMG motif present in the mat A-3 gene. In this work the yeast two-hybrid system was used to identify transcriptional activity and protein-protein interaction of N. crassa mat A-2 and mat A-3 genes. We observed that the mat A-3 protein alone is capable of weakly activating transcription of yeast reporter genes; it also binds with low specificity to the GAL1 promoter sequence, possibly due to its HMG domain. Our results also indicate that mat A-3 is capable to form homodimers, and interact with mat A-2. Interference on yeast growth was observed on some transformants suggesting a toxic action of the mat A-2 protein. Our data on pattern of interactions of mat proteins contributes towards understanding the control of vegetative and sexual cycles in filamentous fungi.

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