Pesquisa | SciELO

ABSTRACT Background: Cases of coronavirus disease 2019 (COVID-19) requiring hospitalization continue to appear in vulnerable populations, highlighting the importance of novel treatments. The hyperinflammatory response underlies the severity of the disease, and targeting this pathway may be useful. Herein, we tested whether immunomodulation focusing on interleukin (IL)-6, IL-17, and IL-2, could improve the clinical outcomes of patients admitted with COVID-19. Methods: This multicenter, open-label, prospective, randomized controlled trial was conducted in Brazil. Sixty hospitalized patients with moderate-to-critical COVID-19 received in addition to standard of care (SOC): IL-17 inhibitor (ixekizumab 80 mg SC/week) 1 dose every 4 weeks; low-dose IL-2 (1.5 million IU per day) for 7 days or until discharge; or indirect IL-6 inhibitor (colchicine) orally (0.5 mg) every 8 hours for 3 days, followed by 4 weeks at 0.5 mg 2x/day; or SOC alone. The primary outcome was accessed in the “per protocol” population as the proportion of patients with clinical improvement, defined as a decrease greater or equal to two points on the World Health Organization’s (WHO) seven-category ordinal scale by day 28. Results: All treatments were safe, and the efficacy outcomes did not differ significantly from those of SOC. Interestingly, in the colchicine group, all participants had an improvement of greater or equal to two points on the WHO seven-category ordinal scale and no deaths or patient deterioration were observed. Conclusions: Ixekizumab, colchicine, and IL-2 were demonstrated to be safe but ineffective for COVID-19 treatment. These results must be interpreted cautiously because of the limited sample size.

https://doi.org/10.1590/0037-8682-0565-2022

DKA and new-onset type 1 diabetes in Brazilian children and adolescents during the COVID-19 pandemic
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Luciano, Thais Milioni

; Halah, Mariana Peduti

; Sarti, Mariana Teresa Alves

; Floriano, Vitor Gonçalves

; Fonseca, Benedito Antônio Lopes da

; Liberatore Junior, Raphael Del Roio

; Antonini, Sonir Rauber

Archives of Endocrinology and Metabolism

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Fev 2022, Volume 66 Nº 1 Páginas 88 - 91

Resumo: En | Texto: En | PDF: En

ABSTRACT We assess the severity and frequency of diabetic ketoacidosis (DKA) in new-onset type 1 diabetes mellitus (T1D) patients and in patients with previous diagnosis of T1D in a referral Brazilian university hospital in the first five months of the COVID-19 pandemic. We also compare the data with data from pre-pandemic periods. Forty-three new-onset T1D patients were diagnosed between April and August of the years 2017, 2018, 2019, and 2020. During the COVID-19 pandemic, the number of new-onset T1D was over twice the number of new-onset T1D in the same period in the three previous years. All the 43 patients survived and are now on outpatient follow-up. We also compared the characteristics of the T1D patients hospitalized between April and August of the years 2017, 2018, and 2019 (32 hospitalizations) to the characteristics of the T1D patients hospitalized between April and August/2020 (35 hospitalizations; 1 patient was hospitalized twice in this period). Fourteen of the 34 patients admitted during the pandemic presented with COVID-19-related symptoms (any respiratory symptom, fever, nausea, vomiting, and diarrhea), but only one had positive SARS-CoV-2 RT-PCR test. Samples from 32 out of these 34 patients were assayed for SARS-CoV-2 antibodies, and four patients were positive for total antibodies (IgM and IgG). In agreement with recent reports from European countries, we observed increased frequency of DKA and severe DKA in new-onset and previously diagnosed T1D children and adolescents in a large referral public hospital in Brazil in the first five months of the COVID-19 pandemic. The reasons for this outcome might have been fear of SARS-CoV-2 infection in emergency settings, the more limited availability of primary healthcare, and the lack of school personnel’s attention toward children’s general well-being.

https://doi.org/10.20945/2359-3997000000433

Gamma variant vertically transmitted from a mild symptomatic pregnant woman associated with fatal neonatal COVID
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Gonçalves-Ferri, Walusa Assad

; Carvalheiro, Cristina Galdonyi

; Mussi-Pinhata, Marisa Marcia

; Cavasin, Bruna Pinto Dias

; Fonseca, Benedito Antonio Lopes da

Brazilian Journal of Infectious Diseases

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2022, Volume 26 Nº 4 elocation 102385

Resumo: En | Texto: En | PDF: En

ABSTRACT Herein we describe a mild symptomatic real-time reverse transcriptase- polymerase chain reaction-confirmed coronavirus 2 (SARS-CoV-2) infection in a pregnant woman who gave birth to a preterm infant, 32 weeks gestational age. The neonate was immediately isolated after delivery and developed severe respiratory disease that progressed to multisystem inflammatory syndrome and death on the seventh day of life. Genome sequencing detected the P.1 (gamma) variant in samples obtained at hospital admission (mother) and on the first (10h) and 13th days of life (neonate). Complete homology (mother’s and newborn’s sequences) confirmed vertical transmission. To our knowledge, this is the first report of vertically-transmitted SARS-CoV-2 P.1 (gamma) variant in a mild symptomatic infection in pregnancy associated with fatal COVID in a neonate.

https://doi.org/10.1016/j.bjid.2022.102385

Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Siconelli, Márcio Junio Lima

; Jorge, Daniel Macedo de Melo

; Castro-Jorge, Luiza Antunes de

; Fonseca-Júnior, Antônio Augusto

; Nascimento, Mateus Laguardia

; Floriano, Vitor Gonçalves

; Souza, Fransérgio Rocha de

; Queiroz-Júnior, Eudson Maia de

; Camargos, Marcelo Fernandes

; Costa, Eliana Dea Lara

; Carvalho, Adolorata Aparecida Bianco

; Fonseca, Benedito Antonio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 54 elocation e0687-2020

Resumo: En | Texto: En | PDF: En

Abstract INTRODUCTION: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. AIM: We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019. METHODS: WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq. RESULTS: Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. CONCLUSIONS: Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.

https://doi.org/10.1590/0037-8682-0687-2020 430 downloads

Prevalence of virological and serological markers of SARS-CoV-2 infection in the population of Ribeirão Preto, Southeast Brazil: an epidemiological survey
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Martinez, Edson Zangiacomi

; Passos, Afonso Dinis Costa

; Fabbro, Amaury Lelis Dal

; Silva, Anderson Soares da

; Escarso, Andreia Cássia

; Pazin-Filho, Antônio

; Fonseca, Benedito Antônio Lopes da

; Maciel, Benedito Carlos

; Araújo, Daniel Cardoso de Almeida e

; Clé, Diego Villa

; Gaspar, Gilberto Gambero

; Santos, Jair Lício Ferreira dos

; Ferreira, Janise Braga Barros

; Souza, João Paulo

; Mello, Luane Marques de

; Santos, Luciane Loures dos

; Passos, Luzia Márcia Romanholi

; Siconelli, Márcio Junio Lima

; Cavalli, Ricardo de Carvalho

; Santana, Rodrigo de Carvalho

; Calado, Rodrigo do Tocantins

; Scarpelini, Sandro

; Bollela, Valdes Roberto

; Floriano, Vitor Gonçalves

; Bellissimo-Rodrigues, Fernando

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 54 elocation e0210-2021

Resumo: En | Texto: En | PDF: En

Abstract INTRODUCTION: This epidemiological household survey aimed to estimate the prevalence of the current and past SARS-CoV-2 infections in Ribeirão Preto, a municipality of southeast Brazil. METHODS: The survey was conducted in two phases using a clustered sampling scheme. The first phase spanned May 1-3 and involved 709 participants. The second phase spanned June 11-14, 2020, and involved 646 participants. RESULTS: During the first phase, RT-PCR performed on nasopharyngeal swabs was positive at 0.14%. The serological tests were positive in 1.27% of the patients during the first phase and 2.79% during the second phase. People living in households with more than five members had a prevalence of 10.83% (95%CI: 1.58-74.27) higher than those living alone or with someone other. Considering the proportion of the positive serological test results with sex and age adjustments, approximately 2.37% (95%CI: 1.32-3.42) of the population had been cumulatively infected by mid-June 2020, which is equivalent to 16,670 people (95%CI: 9,267-24,074). Considering that 68 deaths from the disease in the residents of the city had been confirmed as at the date of the second phase of the survey, the infection fatality rate was estimated to be 0.41% (95%CI: 0.28-0.73). Our results suggest that approximately 88% of the cases of SARS-CoV-2 infection at the time of the survey were not reported to the local epidemiological surveillance service. CONCLUSIONS: The findings of this study provide in-depth knowledge of the COVID-19 pandemic in Brazil and are helpful for the preventive and decision-making policies of public managers.

https://doi.org/10.1590/0037-8682-0210-2021 117 downloads

Are SARS-CoV-2 reinfection and Covid-19 recurrence possible? a case report from Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Bonifácio, Lívia Pimenta

; Pereira, Ana Paula Sulino

; Araújo, Daniel Cardoso de Almeida e

; Balbão, Viviane da Mata Pasti

; Fonseca, Benedito Antônio Lopes da

; Passos, Afonso Dinis Costa

; Bellissimo-Rodrigues, Fernando

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2020, Volume 53 elocation e20200619

Resumo: En | Texto: En | PDF: En

Abstract With the large number of individuals infected and recovered from Covid-19, there is intense discussion about the quality and duration of the immunity elicited by SARS-CoV-2 infection, including the possibility of disease recurrence. Here we report a case with strong clinical, epidemiological and laboratorial evidence of, not only reinfection by SARS-CoV-2, but also clinical recurrence of Covid-19.

https://doi.org/10.1590/0037-8682-0619-2020 5960 downloads

West Nile virus infections are here! Are we prepared to face another flavivirus epidemic?
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Castro-Jorge, Luiza Antunes de

; Siconelli, Márcio Junio Lima

; Ribeiro, Beatriz dos Santos

; Moraes, Flávia Masson de

; Moraes, Jonathan Ballico de

; Agostinho, Mayara Rovariz

; Klein, Taline Monteiro

; Floriano, Vitor Gonçalves

; Fonseca, Benedito Antônio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2019, Volume 52 elocation e20190089

Resumo: En | Texto: En | PDF: En

Abstract Emerging arthropod-borne viruses (arboviruses), such as chikungunya and Zika viruses, are a major threat to public health in countries like Brazil where biodiversity is high and medical care is sometimes precarious. West Nile fever is a disease caused by the West Nile Virus (WNV), an RNA virus belonging to the Flaviviridae family. It is transmitted by infected mosquitoes to numerous animals like birds, reptiles and mammals, including human and non-human primates. In the last decade, the number of reported cases of WNV infection in humans and animals has increased in the Americas. Circulation of WNV in forests and rural areas in Brazil has been detected based on serological surveys and, in 2014, the first case of West Nile fever was confirmed in a patient from Piauí State. In 2018, the virus was isolated for the first time from a horse from a rural area in the state of Espírito Santo presenting with a neurological disorder; this raises the possibility that other cases of WNV encephalitis may have occurred without clinical recognition and without laboratory diagnosis by specific assays. The imminent WNV outbreak poses a challenge for Brazilian clinicians and researchers. In this review, we summarize the basic biological and ecological characteristics of this virus and the clinical presentation and treatment of febrile illnesses caused by WNV. We also discuss the epidemiological aspects, prophylaxis of WNV infections, and monitoring strategies that could be applied in the possibility of a WNV outbreak in Brazil.

https://doi.org/10.1590/0037-8682-0089-2018 4212 downloads

Risk of Zika virus transmission by blood donations in Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Magnus, Mariana Munari

; Espósito, Danillo Lucas Alves

; Costa, Victor Antonio da

; Melo, Priscila Silva de

; Costa-Lima, Carolina

; Fonseca, Benedito Antonio Lopes da

; Addas-Carvalho, Marcelo

Hematology, Transfusion and Cell Therapy

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Set 2018, Volume 40 Nº 3 Páginas 250 - 254

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Zika, a disease caused by Zika virus infections, has recently emerged and caused outbreaks in many parts of the world. The clinical manifestations of Zika are usually mild, mostly presenting as an exanthematic febrile disease, but on some occasions, it might be associated with microcephaly after intrauterine infection, and Guillain-Barré Syndrome. Zika virus is primarily transmitted by mosquito bites, but other means of transmission have been described, and potential risk for blood transmission has been reported in French Polynesia and Brazil. Methods: To investigate the risk of Zika virus infection after a blood transfusion in an area of Brazil where a possible transmission by a platelet concentrate has been described. Using a mini-pool format, 1857 blood donations were evaluated by real-time reverse transcriptase polymerase chain reaction designed to detect Zika virus RNA. Results: After testing samples individually from positive mini-pools, the prevalence of Zika virus RNA was only 0.16%, a result probably associated to the low circulation of this virus in the study area. In addition, it was evident that the implementation of post-surveillance programs is important to detect Zika virus infections in blood donors, as the post-donation surveillance program detected two blood donors with the disease in this study. Conclusion: This study shows that the risk for Zika virus transmission by blood transfusion is real, even in regions with a low circulation of the disease, but the combination of the detection of Zika virus RNA by polymerase chain reaction and post-donation surveillance might reduce the risk of transmission by blood transfusions.

https://doi.org/10.1016/j.htct.2018.01.011 1373 downloads

Zika virus infection followed by a first episode of psychosis: another flavivirus leading to pure psychiatric symptomatology
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Corrêa-Oliveira, Gabriel Elias

; do Amaral, Julia Lopes

; da Fonseca, Benedito Antônio Lopes

; Del-Ben, Cristina Marta

Brazilian Journal of Psychiatry

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Dez 2017, Volume 39 Nº 4 Páginas 381 - 382

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/1516-4446-2017-2308 1477 downloads

10.

Will Mayaro virus be responsible for the next outbreak of an arthropod-borne virus in Brazil?
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Esposito, Danillo Lucas Alves

; Fonseca, Benedito Antonio Lopes da

Brazilian Journal of Infectious Diseases

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Out 2017, Volume 21 Nº 5 Páginas 540 - 544

Resumo: En | Texto: En | PDF: En

Abstract Mayaro virus is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade fever, maculopapular skin rash and marked arthralgia that, in some patients, can persist for long periods after infection and may be misinterpreted as chikungunya. Although only a few outbreaks involving this virus have been reported, in the last years the number of Mayaro virus infections has increased in the central and northern regions of Brazil. In this review, we describe the reported prevalence of this infection over the years and discuss the circumstances that can contribute to the establishment of an urban mayaro virus epidemic in Brazil and the problems encountered with the specific diagnosis, especially the antigenic cross-reactivity of this pathogen with other viruses of the same family.

https://doi.org/10.1016/j.bjid.2017.06.002 3014 downloads

11.

Sensitivity and detection of chikungunya viral genetic material using several PCR-based approaches
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Esposito, Danillo Lucas Alves

; Fonseca, Benedito Antonio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Ago 2017, Volume 50 Nº 4 Páginas 465 - 469

Resumo: En | Texto: En | PDF: En

Abstract INTRODUCTION: Chikungunya fever is a condition resulting from infection by chikungunya virus (CHIKV), an Aedes sp.-transmitted virus. This disease has been diagnosed in thousands of cases in the Americas, particularly in Brazil, in recent years, and there is an ongoing epidemic of chikungunya fever in Brazil that began in 2014. Clinical diagnosis is difficult; only a few cases have been confirmed by laboratory tests due to the low number of specific, efficient tests available for virus or antibody detection. Here, we aimed to evaluate different polymerase chain reaction (PCR) approaches for detection of CHIKV genetic material. METHODS: Specific primers and probes within the viral capsid gene region were designed for this work. To evaluate the analytic sensitivity of detection, human sera were spiked with serial dilutions of the viral stock. Several PCR protocols were performed to investigate the sensitivity of CHIKV RNA detection in serum dilutions ranging from 106 to 1 PFU equivalents. RESULTS: The technique showing the greatest sensitivity was a real-time PCR assay using specific probes that could detect the genetic material of the virus at all dilutions, followed by conventional PCR. Digital PCR showed low sensitivity and was much more expensive than other technologies. Digital PCR should be used for specific purposes other than clinical diagnosis. CONCLUSIONS: Although quantitative PCR using probes was more expensive than the use of intercalating dyes or conventional PCR, it had the highest sensitivity out of all tested PCR approaches.

https://doi.org/10.1590/0037-8682-0403-2016 27719 downloads

12.

Digital disease data: what is the impact on the Zika virus epidemic?
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva, Marcus Vinicius Gomes da

; Esposito, Danillo Lucas Alves

; Fonseca, Benedito Antônio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Ago 2017, Volume 50 Nº 4 Páginas 437 - 438

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/0037-8682-0312-2017 1017 downloads

13.

Zika - The road from an obscure disease to an epidemic of information
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Moraes, Flavia Masson de

; Esposito, Danillo Lucas Alves

; Fonseca, Benedito Antônio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Fev 2017, Volume 50 Nº 1 Páginas 1 - 2

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/0037-8682-0541-2016 1564 downloads

14.

Zika and chikungunya infections in Brazil: reviewing the epidemic and treatment options
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Esposito, Danillo Lucas Alves

; Fonseca, Benedito Antônio Lopes da

Revista da Sociedade Brasileira de Medicina Tropical

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Out 2016, Volume 49 Nº 5 Páginas 535 - 536

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/0037-8682-0428-2016 3022 downloads

15.

A real-time reverse transcriptase polymerase chain reaction for detection and quantification of Vesiculovirus
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Tolardo, Aline Lavado

; Souza, William Marciel de

; Romeiro, Marilia Farignoli

; Vieira, Luiz Carlos

; Luna, Luciano Kleber de Souza

; Henriques, Dyana Alves

; Araujo, Jansen de

; Siqueira, Carlos Eduardo Hassegawa

; Colombo, Tatiana Elias

; Aquino, Victor Hugo

; Fonseca, Benedito Antonio Lopes da

; Bronzoni, Roberta Vieira de Morais

; Nogueira, Maurício Lacerda

; Durigon, Edison Luiz

; Figueiredo, Luiz Tadeu Moraes

Memórias do Instituto Oswaldo Cruz

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2016, Volume 111 Nº 6 Páginas 385 - 390

Resumo: En | Texto: En | PDF: En

Vesiculoviruses (VSV) are zoonotic viruses that cause vesicular stomatitis disease in cattle, horses and pigs, as well as sporadic human cases of acute febrile illness. Therefore, diagnosis of VSV infections by reliable laboratory techniques is important to allow a proper case management and implementation of strategies for the containment of virus spread. We show here a sensitive and reproducible real-time reverse transcriptase polymerase chain reaction (RT-PCR) for detection and quantification of VSV. The assay was evaluated with arthropods and serum samples obtained from horses, cattle and patients with acute febrile disease. The real-time RT-PCR amplified the Piry, Carajas, Alagoas and Indiana Vesiculovirus at a melting temperature 81.02 ± 0.8ºC, and the sensitivity of assay was estimated in 10 RNA copies/mL to the Piry Vesiculovirus. The viral genome has been detected in samples of horses and cattle, but not detected in human sera or arthropods. Thus, this assay allows a preliminary differential diagnosis of VSV infections.

https://doi.org/10.1590/0074-02760150456 26770 downloads

Exibindo

itens por página

Página de 3 Próxima

Selecione um ou mais resultados

Todos Ordem alfabética

Resultados

Gráfico comparativo Download CSV

Visualizar estatísticas de

Enviar resultado

E-mail do(s) destinatários*

Utilize ; (ponto e vírgula) para mais de um e-mail.

Enviar por e-mail

Esta página

Registros selecionados

Todos os registros (max. 300)

Alterar remetente, assunto e comentários

Seu email

Assunto

Comentários

Alterar remetente, assunto e comentários

Exportar resultados

Formato de exportação:

RIS (para EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citação

CSV (para Excel, etc)

Exportar:

Esta página

Itens selecionados

Todos os registros (max. 2000)

Mostrar mais

Sem resultados

Não foram encontrados documentos para sua pesquisa

Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

Todo o conteúdo de www.scielo.org, exceto onde está identificado, está licenciado sob uma Licença Creative Commons.
saiba mais »