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au:DOMINGUEZ, MARIANA

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Effectiveness of enrofloxacin-alginate gel to prevent newborn calves’ navels infection
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Gutiérrez, Lilia

; Rodríguez, Mariana

; Rodríguez, Noe

; Tapia, Graciela

; Dominguez, Diana

; Amigon, Miguel

; Sumano, Héctor

; Posadas-Manzano, Eduardo

Veterinaria México OA

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2022, Volume 9 elocation e1042

Resumo: En | Texto: En | PDF: En

Abstract A trial was conducted with 414 newborn calves randomly divided by riskblocks of developing omphalitis or omphalophlebitis: low; medium, and high. The treatments were applied by stump-dipping daily for three days, with either iodine-polyvinylpyrrolidone (I-PVP) (n = 205), or with an alginate gel containing 0.5 % enrofloxacin hydrochloride dehydrate (enro-C) (n = 209). Results showed that only one death occurred in the enro-C group, which was attributable to internal hemorrhage not linked with the treatment. After four days, we recorded six other cases as stump fibrosis, but these were inconsequential. In the I-PVP group, 44 calves developed cord infection and were considered treatment failures (13 high-risk; 11 medium-risk, and 20 low-risk) (P < 0.0435 in the three risk grades). The umbilical stump involution was evident in the enro-C-treated animals on day one as most stumps were noticeably dried. Stump detachment occurred within an average of nearly 30 days, and the umbilical scars did not present infection in any case. Conversely, in the remaining calves of the I-PVP group, stump drying was observable after 72 h, and it detached within an average of 32 days (P < 0.05). In stumps treated with enro-C, dirt stuck less, and the gel formed an apparently protecting layer around the umbilical scar when stump was either absent or too short. These results show that enro-C is a successful preventive treatment that allows rapid umbilical stump involution in newborn calves.

https://doi.org/10.22201/fmvz.24486760e.2022.1042

Calidad microbiológica del aire en un Centro Comunitario de Salud Familiar de Talcahuano, Región del Biobío, Chile
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Parra-Donoso, Marco

; Valdebenito-Rolack, Emky

; Cid-Maldonado, Nicole

; Dominguez-Yévenes, Mariana

; Sanhueza-Gomez, Felipe

; Salvo, Christopher

; Lopez-Jenssen, Marta

; Bournas, Paula

; Bello-Toledo, Helia

Revista chilena de infectología

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Jun 2021, Volume 38 Nº 3 Páginas 324 - 332

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Background: Indoor air quality in health centers is essential to protect the health of people. In Chile, the Community Family Health Centers (CECOSF) are places with large attendance of people, favoring the dissemination of microorganisms, and there are no reports of the microbial air loading these health centers. Aim: To evaluate the microbiological indoor air quality in CECOSF-Centinela in Talcahuano, Biobío Region. Methods: Air samples were taken in 6 rooms of the CECOSF, every 15 days between July 2018 and June 2019, with the MAS-100 NT equipment using trypticase and Sabouraud agars. Different morphotypes of bacteria and fungi were identified by PCR. Results: The bacterial and fungal counts varied between 9.1 × 101 - 2.4 × 103 cfu/m3 and 10 – 1.5 × 102 cfu/m3, respectively. The air in the waiting room presented the highest counts, both for bacteria and fungi (P < 0.05). Staphylococcus, Enterococcus, Pseudomonas, Acinetobacter were identified, highlighting the species Staphylococcus aureus and Pseudomonas oryzihabitans, the latter described as a nosocomial pathogen. Among the fungi, Aspergillus, Meyerozyma and Rhodotorula were identified. Conclusion: The indoor air of the CECOSF-Centinela presents microorganisms of importance in human health. Therefore, it is necessary to formulate more regular monitoring programs for the control of air quality inside these health centers.

Resumen Introduccción: La calidad del aire en centros de salud es fundamental para resguardar la salud de las personas. En Chile, los Centros Comunitarios de Salud Familiar (CECOSF) son lugares de gran concurrencia de personas, favoreciendo la diseminación de microorganismos. Objetivo: Evaluar la calidad microbiológica del aire al interior del CECOSF-Centinela en Talcahuano, Región del Biobío. Metodología: Se tomó muestras de aire en seis salas del CECOSF, quincenalmente, entre julio de 2018 y junio de 2019, con el equipo MAS-100 NT, empleando agar tripticasa y agar Sabouraud. Diferentes morfotipos de bacterias y hongos fueron identificados mediante RPC. Resultados: Los recuentos de bacterias y hongos variaron entre 9,1 × 101 – 2,4 × 103 ufc/m3 y 10 – 1,5 × 102 ufc/m3, respectivamente. El aire de la sala de espera presentó los recuentos más altos, tanto para bacterias como hongos (P < 0,05). Se identificó Staphylococcus, Enterococcus, Pseudomonas, Acinetobacter, destacando las especies Staphylococcus aureus y Pseudomonas oryzihabitans, microrganismo este último, descrito actualmente como patógeno nosocomial. Entre los hongos se identificó Aspergillus, Meyerozyma y Rhodotorula. Conclusión: Las muestras de aire del CECOSF-Centinela presentan microrganismos de importancia en salud humana. De ahí la necesidad de formular programas de monitoreo más regulares para controlar la calidad del aire al interior de estos establecimientos.

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Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans
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Kehdy, Fernanda S.G.

; Pita-Oliveira, Murilo

; Scudeler, Mariana M.

; Torres-Loureiro, Sabrina

; Zolini, Camila

; Moreira, Rennan

; Michelin, Lucas A.

; Alvim, Isabela

; Silva-Carvalho, Carolina

; Furlan, Vinicius C.

; Aquino, Marla M.

; Santolalla, Meddly L.

; Borda, Victor

; Soares-Souza, Giordano B.

; Jaramillo-Valverde, Luis

; Vasquez-Dominguez, Andres

; Neira, Cesar Sanchez

; Aguiar, Renato S.

; Verdugo, Ricardo A.

; O`Connor, Timothy D.

; Guio, Heinner

; Tarazona-Santos, Eduardo

; Leal, Thiago P.

; Rodrigues-Soares, Fernanda

Genetics and Molecular Biology

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2021, Volume 44 Nº 1 elocation e20200484

Resumo: En | Texto: En | PDF: En

Abstract For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the importance of population genetics and of sequencing data in the design of genetic association studies in different human populations: the high linkage disequilibrium (LD) between rs2070788 and rs383510 is Asian-specific. Leveraging on a combination of genotyping and sequencing data for Native Americans (neglected in genetic studies), we show that while their frequencies of the Asian tag-SNP rs2070788 is, surprisingly, the highest worldwide, it is not in LD with the eQTL rs383510, that therefore, should be directly genotyped in genetic association studies of SARS in populations with Native American ancestry.

https://doi.org/10.1590/1678-4685-gmb-2020-0484 193 downloads

São Paulo School of Advanced Sciences on Vaccines: an overview
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Sorgi, Sara

; Bonezi, Vivian

; Dominguez, Mariana R.

; Gimenez, Alba Marina

; Dobrescu, Irina

; Boscardin, Silvia

; Nakaya, Helder I.

; Bargieri, Daniel Y.

; Soares, Irene S.

; Silveira, Eduardo L. V.

Journal of Venomous Animals and Toxins including Tropical Diseases

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2020, Volume 26 elocation e20190061

Resumo: En | Texto: En | PDF: En

Abstract Two years ago, we held an exciting event entitled the São Paulo School of Advanced Sciences on Vaccines (SPSASV). Sixty-eight Ph.D. students, postdoctoral fellows and independent researchers from 37 different countries met at the Mendes Plaza Hotel located in the city of Santos, SP - Brazil to discuss the challenges and the new frontiers of vaccinology. The SPSASV provided a critical and comprehensive view of vaccine research from basics to the current state-of-the-art techniques performed worldwide. For 10 days, we discussed all the aspects of vaccine development in 36 lectures, 53 oral presentations and 2 poster sessions. At the end of the course, participants were further encouraged to present a model of a grant proposal related to vaccine development against individual pathogens. Among the targeted pathogens were viruses (Chikungunya, HIV, RSV, and Influenza), bacteria (Mycobacterium tuberculosis and Streptococcus pyogenes), parasites (Plasmodium falciparum or Plasmodium vivax), and the worm Strongyloides stercoralis. This report highlights some of the knowledge shared at the SPSASV.

https://doi.org/10.1590/1678-9199-jvatitd-2019-0061 1427 downloads

Bilateral pulmonary interstitial emphysema in a preterm infant on continuous positive airway pressure: clinical and radiological correlation
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Dominguez, Mariana Chiaradia

; Pires, Camila da Silva

; Stopiglia, Mônica Carvalho Sanchez

; Mezzacappa, Maria Aparecida Marques dos Santos

; Alvares, Beatriz Regina

Radiologia Brasileira

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Abr 2018, Volume 51 Nº 2 Páginas 137 - 138

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0100-3984.2016.0198 1951 downloads

Pulmonary atelectasis in newborns with clinically treatable diseases who are on mechanical ventilation: clinical and radiological aspects
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Dominguez, Mariana Chiaradia

; Alvares, Beatriz Regina

Radiologia Brasileira

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Fev 2018, Volume 51 Nº 1 Páginas 20 - 25

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Analisar os aspectos radiológicos da atelectasia pulmonar em recém-nascidos com doenças clinicamente tratáveis submetidos a ventilação mecânica e atendidos em uma unidade de tratamento intensivo neonatal, associando características da atelectasia com o posicionamento da cabeça e da cânula endotraqueal na radiografia de tórax e com variáveis clínicas. Materiais e Métodos: Estudo de corte transversal e retrospectivo, em que foram incluídos 60 pacientes internados entre 1985 e 2015. A coleta dos dados foi realizada por meio da revisão dos prontuários e dos laudos das radiografias dos recém-nascidos. Para associação das variáveis foi realizado o teste exato de Fisher. O nível de significância adotado foi p < 0,05. Resultados: As características clínicas associadas à localização inadequada da cânula foram prematuridade e o peso ao nascer inferior a 1000 g. A doença clínica mais frequentemente encontrada foi a doença da membrana hialina. O lobo pulmonar superior direito foi o que apresentou maior frequência de atelectasia, e casos de atelectasia completa foram mais frequentes no pulmão esquerdo. O mau posicionamento da cabeça mostrou uma tendência de associação com atelectasia no lobo superior esquerdo. Conclusão: A atelectasia pulmonar representou uma complicação importante em recém-nascidos submetidos a ventilação mecânica, sendo a avaliação radiológica do posicionamento da cânula endotraqueal relevante para a correção precoce dessa condição.

Abstract Objective: To analyze the radiological aspects of pulmonary atelectasis in newborns on mechanical ventilation and treated in an intensive care unit, associating the characteristics of atelectasis with the positioning of the head and endotracheal tube seen on the chest X-ray, as well as with the clinical variables. Materials and Methods: This was a retrospective cross-sectional study of 60 newborns treated between 1985 and 2015. Data were collected from medical records and radiology reports. To identify associations between variables, we used Fisher's exact test. The level of significance was set at p < 0.05. Results: The clinical characteristics associated with improper positioning of the endotracheal tube were prematurity and a birth weight of less than 1000 g. Among the newborns evaluated, the most common comorbidity was hyaline membrane disease. Atelectasis was seen most frequently in the right upper lobe, although cases of total atelectasis were more common in the left lung. Malpositioning of the head showed a trend toward an association with atelectasis in the left upper lobe. Conclusion: Pulmonary atelectasis is a common complication in newborns on mechanical ventilation. Radiological evaluation of the endotracheal tube placement provides relevant information for the early correction of this condition.

https://doi.org/10.1590/0100-3984.2016.0157 19853 downloads

Risk factors for candidemia mortality in hospitalized children
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Motta, Fabio Araujo

; Dalla-Costa, Libera Maria

; Muro, Marisol Dominguez

; Cardoso, Mariana Nadal

; Picharski, Gledson Luiz

; Jaeger, Gregory

; Burger, Marion

Jornal de Pediatria

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Abr 2017, Volume 93 Nº 2 Páginas 165 - 171

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Avaliar os fatores de risco associados ao óbito por infecção da corrente sanguínea causada pela Candida spp em pacientes pediátricos e avaliar a resistência ao principal antifúngico usado na prática clínica. Métodos: Este é um estudo transversal, observacional e analítico com coleta retrospectiva que incluiu 65 pacientes pediátricos internados com infecção da corrente sanguínea por Candida spp. Foi feita uma análise univariada para estimar a associação entre as características dos pacientes com candidemia e o óbito. Resultados: A incidência de candidemia foi de 0,23 casos em cada 1.000 pacientes/dia, com taxa de mortalidade de 32% (n = 21). O resultado clínico como sepse e choque séptico (p = 0,001), comorbidades como insuficiência renal aguda (p = 0,01) e riscos como ventilação mecânica (p = 0,02) e diálise (p = 0,03) estão associados ao aumento da mortalidade em pacientes pediátricos. As taxas de resistência e susceptibilidade dose-dependente contra o fluconazol foram de 4,2% e 2,1%, respectivamente. Não foi identificada resistência à anfotericina B e equinocandina. Conclusão: Os dados de nosso estudo sugerem que a sepse e o choque séptico, a insuficiência renal aguda e riscos como ventilação mecânica e diálise estão associados ao aumento da mortalidade em pacientes pediátricos. A mortalidade entre pacientes com candidemia é alta e não há diferença nas taxas de mortalidade entre as espécies. Sobre a resistência, é importante enfatizar a presença de baixa resistência nesta série.

Abstract Objective: To evaluate risk factors associated with death due to bloodstream infection caused by Candida spp. in pediatric patients and evaluate the resistance to the main anti-fungal used in clinical practice. Methods: This is a cross-sectional, observational, analytical study with retrospective collection that included 65 hospitalized pediatric patients with bloodstream infection by Candida spp. A univariate analysis was performed to estimate the association between the characteristics of the candidemia patients and death. Results: The incidence of candidemia was 0.23 cases per 1000 patients/day, with a mortality rate of 32% (n = 21). Clinical outcomes such as sepsis and septic shock (p = 0.001), comorbidities such as acute renal insufficiency (p = 0.01), and risks such as mechanical ventilation (p = 0.02) and dialysis (p = 0.03) are associated with increased mortality in pediatric patients. The resistance and dose-dependent susceptibility rates against fluconazole were 4.2% and 2.1%, respectively. No resistance to amphotericin B and echinocandin was identified. Conclusion: Data from this study suggest that sepsis and septic shock, acute renal insufficiency, and risks like mechanical ventilation and dialysis are associated with increased mortality in pediatric patients. The mortality among patients with candidemia is high, and there is no species difference in mortality rates. Regarding the resistance rates, it is important to emphasize the presence of low resistance in this series.

https://doi.org/10.1016/j.jped.2016.05.007 2964 downloads

Enterococcus spp. isolated from root canals with persistent chronic apical periodontitis in a Chilean population
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Sánchez-Sanhueza, Gabriela

; González-Rocha, Gerardo

; Dominguez, Mariana

; Bello-Toledo, Helia

Brazilian Journal of Oral Sciences

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Set 2015, Volume 14 Nº 3 Páginas 240 - 245

Resumo: En | Texto: En | PDF: En

Abstract Aim: To isolate and identify in a Chilean population,Enterococcus spp. from root canals with persistent chronic apical periodontitis (CAP) and to investigate the potential correlation between the bacteria and the observed clinical features. Methods: Twenty patients with indication for endodontic retreatment due to persistent CAP were selected. Data from patient general health and dental clinical history were recorded. During retreatment, a microbial sample was obtained from the root canal and inoculated in a selectiveEnterococcus medium. Using bacterial cultivation methods, bacterial isolates belonging to the genusEnterococcus were identified. The relationship between the number of colony-forming units of Enterococcus spp. and patient clinical data was assessed statistically by the Pearson Chi square and Fisher exact tests. Finally, a Polymerase Chain Reaction (PCR) assay to determine the most prevalent species of Enterococcus spp. was conducted in the clinical samples, and the results were analyzed by a proportion comparison test. Results: Enterococcus spp. strains were isolated in 70% of the patients. Most of them (98.8%) accounted for Enterococcus faecalis and only 1.2% for Enterococcus faecium. A high frequency of E. faecalis was found in teeth with inadequate endodontic treatment or dental crown restorations. Conclusions: This study concluded that E. faecalis is prevalent in root canals with persistent CAP in a Chilean population. E. faecium as found in a single case with the poorest root canal filling. Further studies are still required to investigate the presence of other species, which may be linked to persistent chronic apical periodontitis.

https://doi.org/10.1590/1677-3225v14n3a13 2287 downloads

Applicability of Moyers analysis in mixed dentition: A systematic review
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Galvão, Mariana de Aguiar Bulhões

; Dominguez, Gladys Cristina

; Tormin, Sérgio Thomaz

; Akamine, Alex

; Tortamano, André

; Fantini, Solange Mongelli de

Dental Press Journal of Orthodontics

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Dez 2013, Volume 18 Nº 6 Páginas 100 - 105

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

INTRODUÇÃO: a análise de Moyers é amplamente adotada para a análise da dentição mista, porém, recentemente, a acurácia das suas tabelas de probabilidade está sendo questionada. OBJETIVO: sabendo-se da importância da análise da dentição mista, na determinação mais precisa possível do espaço necessário para o alinhamento de caninos e pré-molares, o objetivo dessa pesquisa foi avaliar de forma objetiva na literatura este importante passo do diagnóstico ortodôntico. MÉTODOS: foi realizado um levantamento computadorizado de artigos publicados entre os anos de 1990 a setembro de 2011 nas bases de dados PubMed e LILACS, segundo o método descrito no manual Cochrane 5.1.0. RESULTADOS: a estratégia de busca resultou em 629 artigos. Para ser selecionado, o artigo deveria utilizar a análise de Moyers e ter uma amostra superior ou igual a 40 pacientes. Os critérios de exclusão foram: modelos de gesso de pacientes com algum tipo de síndrome ou fissurados, pesquisas cuja proposta era apenas uma revisão da literatura ou apenas relato de um caso clínico, e pesquisas anteriores ao ano de 1990. Para essa revisão sistemática, 19 artigos foram selecionados. CONCLUSÕES: com base na literatura disponível, pode-se concluir que a utilização da análise de Moyers na análise da dentição mista deve ser utilizada de maneira cautelosa, pois, na maioria dos artigos avaliados, 75% não apresentou a acurácia desejada, necessitando de adaptações nos níveis de probabilidade, dependendo da população em estudo.

INTRODUCTION: Moyers analysis is widely used for analyzing mixed dentition, however, the accuracy of its theoretical probability tables has been recently questioned. Taking into consideration the fact the mixed dentition analysis is of paramount importance to precisely determine the space needed for alignment of canines and premolars, this research aimed at objectively assessing in the literature such an important step for orthodontic diagnosis. METHODS: A computerized search involving articles published on PubMed and Lilacs between 1990 and September, 2011 was conducted in accordance with the method described in the Cochrane 5.1.0 handbook. RESULTS: The research resulted in a sample composed of 629 articles. The inclusion criteria were: Articles using the Moyers analysis with a sample greater or equal to 40 patients. Conversely, the exclusion criteria were: Dental casts of patients with syndromes or oral cleft, researches conducted with a literature review, only, or clinical case reports and researches conducted before 1990. For this systematic review, 19 articles were selected. CONCLUSION: Based on the literature available, we can conclude that the Moyers mixed dentition analysis must be carefully used, since the majority of the articles analyzed showed that the probability of 75% was not as accurate as expected, leading to the need of adapting the probability levels depending on the study population.

11971 downloads

10.

Swimming against the current: genetic vaccination against Trypanosoma cruzi infection in mice
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Rodrigues, Mauricio M

; Alencar, Bruna C de

; Claser, Carla

; Tzelepis, Fanny

; Silveira, Eduardo L

; Haolla, Filipe A

; Dominguez, Mariana R

; Vasconcelos, José Ronnie

Memórias do Instituto Oswaldo Cruz

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Jul 2009, Volume 104 Supl. 1 Páginas 281 - 287

Resumo: En | Texto: En | PDF: En

Vaccines have had an unquestionable impact on public health during the last century. The most likely reason for the success of vaccines is the robust protective properties of specific antibodies. However, antibodies exert a strong selective pressure and many microorganisms, such as the obligatory intracellular parasite Trypanosoma cruzi, have been selected to survive in their presence. Although the host develops a strong immune response to T. cruzi, they do not clear the infection and instead progress to the chronic phase of the disease. Parasite persistence during the chronic phase of infection is now considered the main factor contributing to the chronic symptoms of the disease. Based on this finding, containment of parasite growth and survival may be one method to avoid the immunopathology of the chronic phase. In this context, vaccinologists have looked over the past 20 years for other immune effector mechanisms that could eliminate these antibody-resistant pathogens. We and others have tested the hypothesis that non-antibody-mediated cellular immune responses (CD4+ Th1 and CD8+ Tc1 cells) to specific parasite antigens/genes expressed by T. cruzi could indeed be used for the purpose of vaccination. This hypothesis was confirmed in different mouse models, indicating a possible path for vaccine development.

2185 downloads

11.

Propiedades microbiológicas, clasificación y relación estructura-actividad de cefalosporinas e importancia de las cefalosporinas de cuarta generación
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MELLA M, SERGIO

; ZEMELMAN M, CLAUDIA

; BELLO T, HELIA

; DOMINGUEZ Y, MARIANA

; GONZALEZ R, GERARDO

; ZEMELMAN Z, RAUL

Revista chilena de infectología

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2001, Volume 18 Nº 1 Páginas 7 - 19

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

The cephalosporins are one of the most important types of ß-lactam antibiotics. There are various classifications of these molecules, but the most frecuently used classifies them according to their structures, microbiological properties and historical development: first to fourth generation cephalosporins. Third generation cephalosporins have been extensively used, but the emergence of bacterial resistance, mainly as a consecuence of chromosomal and plasmidial production of ß-lactamases has limited the use of these antibiotics. Fourth generation cephalosporins are characterized by the presence of a cuaternary nitrogen in C3; mantaining the methoxyimino aminothiazolyl in C7. Fourth generation cephalosporins display a high capacity of intracellular penetration through the external membranes of Gram negative rods and a low affinity to enzymes that degrade third generation cephalosporins. Cefepime, a fourth generation cephalosporin, has shown more inhibitory activity against chilean strains of Klebsiella pneumoniae and Escherichia coli that produce extended-spectrum ß-lactamases, than cefotaxime and ceftazidime

Las cefalosporinas son uno de los grupos de mayor importancia dentro de los ß-lactámicos. Existen diversas clasificaciones de estas moléculas, siendo la más utilizada aquella que agrupa a estos compuestos de acuerdo a propiedades estructurales, microbiológicas y desarrollo histórico: primera a cuarta generación. Las cefalosporinas de tercera generación han sido ampliamente utilizadas, pero la emergencia de resistencia bacteriana fundamentalmente derivada de la producción de ß-lactamasas tanto cromosomales como plasmidiales, ha limitado el uso de estos compuestos. Las cefalosporinas de cuarta generación se caracterizan por la presencia de un nitrógeno cuaternario en C3, además de mantener el grupo metoxi-imino aminotiazolil en C7. Presentan una elevada penetración intracelular a través de la membrana externa de bacilos Gram negativos y tienen una baja afinidad por enzimas que degradan cefalos-porinas de tercera generación. Cefepime, una cefalosporina de cuarta generación, demostró una mayor actividad inhibitoria sobre cepas chilenas de Klebsiella pneumoniae y Escherichia coli productoras de ß-lactamasas de espectro extendido, que cefotaxima y ceftazidima

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12.

Aislamiento de Acinetobacter spp. desde muestras clínicas en el Hospital Clínico Regional "Guillermo Grant Benavente", Concepción
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DOMINGUEZ Y, MARIANA

; SEPULVEDA A, MARCELA

; BELLO T, HELIA

; GONZALEZ R, GERARDO

; MELLA M, SERGIO

; ZEMELMAN Z, RAUL

Revista chilena de infectología

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2000, Volume 17 Nº 4 Páginas 321 - 325

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Since Acinetobacter has become an important nosocomial pathogen, the aim of this study was to investigate the different species of this genus involved in infections in the main hospital of the city of Concepción between August 1998 and December 1999. One hundred-thirteen Acinetobacter strains were isolated mainly from respiratory tract and wound secretions. The majority of isolates came from intensive care unit patients, followed by patients hospitalized in trauma and surgery services. Strains were identified at species level and Acinetobacter baumannii isolates were biotyped using phenotypic tests. A. baumannii was the most frequent species found, and biotypes 9, 6 and 8 predominated in this nosocomial center.

Debido a que Acinetobacter se ha transformado en un importante patógeno intrahospitalario el objetivo de este estudio fue investigar las especies de este género que se encontraban involucradas en procesos infecciosos en el principal centro hospitalario de la ciudad de Concepción, en el periodo comprendido entre agosto de 1998 y diciembre de 1999. Se recolectaron 113 cepas de Acinetobacter, aisladas principalmente de secreciones del tracto respiratorio y heridas. El mayor número de aislamientos tuvo su origen en pacientes internados en la unidad de cuidado intensivo, seguido de pacientes que se encontraban en los servicios de traumatología y cirugía. La identificación de especie y la biotipificación de Acinetobacter baumannii se realizó mediante pruebas fenotípicas. A. baumannii fue la especie predominante, siendo los biotipos 9, 6 y 8 los prevalentes en este centro hospitalario

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13.

Quinolonas: Aspectos generales sobre su estructura y clasificación
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MELLA M., SERGIO

; ACUÑA L., GUILLERMO

; MUÑOZ Q., MARITZA

; PEREZ C., CARLOS

; LABARCA L., JAIME

; GONZALEZ R., GERARDO

; BELLO T., HELIA

; DOMINGUEZ Y., MARIANA

; ZEMELMAN Z., RAUL

Revista chilena de infectología

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2000, Volume 17 Nº 1 Páginas 53 - 66

Resumo: Es | Texto: Es | PDF: Es

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