Abstract The flotation mechanism of galena with xanthate as the collector is generally explained based on the mixed potential of the pulp, in which an anodic electron transfer reaction from the collector to the mineral is combined with an O2 cathodic reduction. Sodium sulphide, often used as a mineral activator, strongly influences the pulp's mixed potential, and depending on the dosage applied, it can become a galena depressor reagent. In this way, the current study assesses galena flotability in the absence of collector, as well as in the presence of the collector potassium amyl xanthate (PAX) and sodium sulphide. The effect of an extremely cathodic potential was also studied through the addition of hydrogen peroxide. In addition, the effect of different stages in the oxidation of the galena surface on the flotability was investigated. Moreover, the zeta potential was measured and contact angle (wettability) tests were carried out. The contact angle measurements were taken for a distilled water, PAX solution and for a mixture of PAX and sodium sulphide solution on the oxidized and non-oxidized surface of galena. All the results showed that galena could be floated in all the PAX concentrations tested. It was observed that a moderate oxidation in the galena surface may contribute to an improvement of its flotation with PAX. However, extremely anodic and cathodic potentials cause flotability close to zero. The zeta potential results showed that sodium sulphide affected the interaction between PAX and galena. The measurements of the contact angle corroborated the results obtained in the microflotation tests. pulp O reduction activator pulps s applied reagent way (PAX peroxide investigated Moreover wettability (wettability out water nonoxidized non tested However zero

Abstract Objective Evaluate autonomic function and low-grade inflammation and characterize the correlation between these variables in schoolchildren with obesity living in the Brazilian northeast region. Methods 84 children with obesity and 41 with normal weight were included in this cross-sectional study. Anthropometry, body composition, blood pressure (BP), inflammatory biomarkers, and heart rate variability (HRV) indexes were analyzed in children aged 7 to 11 years. Results children with obesity had increased systolic (p= 0.0017) and diastolic (p= 0.0131) BP and heart rate (p= 0.0022). The children with obesity displayed significantly lower SDNN, RMSSD, NN50, HF (ms), HF (nu), SD1, SD2, and higher LF (ms), LF (nu), LF/HF, SD1/SD2, DFA-α1, and DFA-α2, compared to normal weight. A lower and higher capacity for producing IL-10 (p= 0.039) and IL-2 (p= 0.009), respectively, were found in children with obesity compared to children with normal weight. Although IL-2, IL-4 and IL17A did not correlate with HRV parameters, IL-6 was positively correlated with SDNN, LF (ms) and SD2, TNF-α was positively correlated with LF/HF and SD1/SD2 ratio, and IFN-γ was positively correlated with SDNN, RMMSSD, NN50, LF (ms), HF (ms), SD1, and SD2. Conclusions The findings suggest that children with obesity have impaired autonomic function and systemic low-grade inflammation compared to children within the normal weight range, the inflammatory biomarkers were correlated with HRV parameters in schoolchildren living in the northeastern region of Brazil.

RESUMEN La coledocolitiasis es una patología obstructiva frecuente de las vías biliares, pudiendo llevar a una serie de síntomas y complicaciones. Presentamos una paciente femenina, de 64 años con antecedente de co- lecistectomía 30 años antes, que acude con dolor epigástrico de 6 días de evolución, ictericia, coluria y acolia. Al ingreso se diagnostica por colangioresonancia, ictericia obstructiva de etiología litiásica. El cuadro no pudo resolverse por colangiopancreatografía retrógrada endoscópica y se resuelve por vía laparoscópica.

ABSTRACT Choledocholitiasis is a common obstructive pathology of the bile ducts, which can lead to a series of symptoms and complications. We present a 64-year-old female patient, with a history of cholecystectomy 30 years ago, who presented with epigastric pain, jaundice, choluria and acholia for six days. Upon admission obstructive jaundice related to gallstones was diagnosed by MRCP. The condition could not be resolved by ERCP and was resolved with a laparoscopic approach.

ABSTRACT Introduction: Acute Kidney Injury (AKI), a frequent manifestation in COVID-19, can compromise kidney function in the long term. We evaluated renal function after hospital discharge of patients who developed AKI associated with COVID-19. Methods: This is an ambidirectional cohort. eGFR and microalbuminuria were reassessed after hospital discharge (T1) in patients who developed AKI due to COVID-19, comparing the values with hospitalization data (T0). P < 0.05 was considered statistically significant. Results: After an average of 16.3 ± 3.5 months, 20 patients were reassessed. There was a median reduction of 11.5 (IQR: –21; –2.1) mL/min/1.73m2 per year in eGFR. Forty-five percent of patients had CKD at T1, were older, and had been hospitalized longer; this correlated negatively with eGFR at T1. Microalbuminuria was positively correlated with CRP at T0 and with a drop in eGFR, as well as eGFR at admission with eGFR at T1. Conclusion: There was a significant reduction in eGFR after AKI due to COVID-19, being associated with age, length of hospital stay, CRP, and need for hemodialysis.

RESUMO Introdução: A Injúria Renal Aguda (IRA), uma manifestação frequente na COVID-19, pode comprometer a função renal em longo prazo. Avaliamos a função renal após a alta hospitalar de pacientes que desenvolveram IRA associada à COVID-19. Métodos: Esta é uma coorte ambidirecional. A TFGe e a microalbuminúria foram reavaliadas após a alta hospitalar (T1) em pacientes que desenvolveram IRA devido à COVID-19, comparando os valores com dados de hospitalização (T0). P < 0,05 foi considerado estatisticamente significativo. Resultados: Após uma média de 16,3 ± 3,5 meses, 20 pacientes foram reavaliados. Houve uma redução média de 11,5 (IIQ: –21; –2,1) mL/min/1,73m2 por ano na TFGe. Quarenta e cinco por cento dos pacientes apresentaram DRC no T1, eram mais velhos e haviam sido hospitalizados por mais tempo; isso se correlacionou negativamente com a TFGe no T1. A microalbuminúria foi positivamente correlacionada com a PCR no T0 e com uma queda na TFGe, assim como a TFGe na admissão com a TFGe no T1. Conclusão: Houve uma redução significativa na TFGe após IRA devido à COVID-19, sendo associada à idade, tempo de internação, PCR e necessidade de hemodiálise.

Abstract Evaluate the shaping ability and preparation time using a pediatric motor-driven rotary instrumentation compared to other systems in resin prototypes of primary molars. Methods: Thirty specimens were scanned in micro-CT and divided into three groups according to the instrumentation type: pediatric motor-driven Sequence baby File (SBF); conventional motor-driven (Sequence Rotary File - SRF); manual K file. Instrumentation time was timed. After preparation, the specimens were scanned again. The pre- and post-instrumentation images were superimposed to measure the amount of root canal deviation and the resin remnant thickness. ANOVA followed by the Tukey test analyzed the comparisons between groups (p<0.05). Results: No statistically significant differences occurred in root canal deviation among groups (p>0.05). There were statistically significant differences in the comparison among root thirds (p<0.001) but without significant differences in the interaction group vs. root third (p>0.05). Both motor-driven instrumentations showed statistically greater weariness than manual instrumentation (p<0.001), without significant significant differences between SBF and SRF. Motor-driven instrumentation had a shorter working time than manual instrumentation (p<0.001). Conclusion: Pediatric motor-driven instrumentation demonstrated good outcomes in relation to root canal deviation and amount of remnant structure, with shorter instrumentation time. SBF can be a suitable alternative for endodontic instrumentation in primary molars.

Resumo Objetivo: Avaliar os resultados da instrumentação endodôntica e o tempo de preparo de lima odontopediátrica ativada por motor (Sequence Baby File- SBF) em canais de molares decíduos prototipados. Métodos: Trinta espécimes foram escaneados em micro-CT e divididos em três grupos de acordo com o tipo de instrumentação: mecanizada odontopediátrica (SBF); mecanizada convencional; lima K manual. O tempo de instrumentação foi cronometrado. Após o preparo, os espécimes foram escaneados novamente. As imagens pré e pós-instrumentação foram sobrepostas e a quantidade de desvio do canal radicular e a espessura de resina remanescente foram mensurados. Para as análises de comparações entre os grupos foram realizados teste ANOVA seguido do teste de Tukey (p<0,05). Resultados: Não ocorreram diferenças estatisticamente significativas entre os grupos no desvio do canal radicular (p>0,05). Houve diferenças estatisticamente significativas na comparação entre terços radiculares (p<0,001), mas sem diferenças significativas na interação grupo vs. terço radicular (p>0,05). A instrumentação mecanizada apresentou desgaste estatisticamente maior do que a instrumentação manual (p<0,001), sem diferenças estatísticas entre a SBF e a lima mecanizada convencional. A instrumentação mecanizada teve menor tempo de trabalho quando comparado a instrumentação manual (p<0,001). Conclusão: A instrumentação mecanizada odontopediátrica demonstrou bons resultados em relação ao desvio do canal radicular e quantidade de estrutura remanescente, com menor tempo de instrumentação. A SBF pode ser uma alternativa adequada para a instrumentação endodôntica em molares decíduos.

ABSTRACT Most soils are excessively acidic, which decreases the productive efficiency of plants. There are several ways to correct soil acidity to make nutrients available to crops. Wood ash is a residue generated by the combustion of vegetal biomass and is used to correct soil acidity for use as a fertilizer. The application of organomineral wood ash to crops is yet another alternative fertilizer that reduces the doses of wood ash and mineral fertilizer. The objective of this study was to evaluate the biomass production and water use efficiency of chrysanthemum cultivated with organic, mineral, and organomineral fertilizers associated with liming. The greenhouse experiment was conducted in a 5 × 2 factorial randomized block design with five fertilization managements (incubated wood ash, non-incubated wood ash, organomineral, mineral fertilization, and control) and two liming values (0 and 100% of the recommendation), with five replicates. Biomass production was significantly affected by fertilization alone and organomineral application resulted in higher biomass production. Incubated ash was more appropriate because resulted in higher yields.

RESUMO A maioria dos solos tem uma acidez excessiva que diminui a eficiência produtiva das plantas. Existem diversas formas de corrigir a acidez do solo e disponibilizar nutrientes para as culturas. A cinza vegetal é um resíduo gerado pela combustão da biomassa vegetal utilizada na correção da acidez do solo e como fertilizante. O organomineral utilizando como matéria prima a cinza vegetal é uma outra alternativa de fertilizante, reduzindo o volume de cinza vegetal e adubo mineral utilizados no campo. Objetivou-se por esta pesquisa avaliar a produção de biomassa e eficiência no uso da água no cultivo de Crisântemo sob adubação orgânica, mineral e organomineral associada a calagem. O experimento foi realizado em casa de vegetação em delineamento de blocos casualizados, com esquema fatorial 5 × 2, sendo cinco manejos de adubações (cinza de madeira incubada, cinza de madeira não incubada, organomineral, adubação mineral e controle) e dois níveis de calagem (0 e 100% da recomendação), com cinco repetições. A produção de biomassa foi significativa somente para adubação de forma isolada e o organomineral demonstrou maior produção de biomassa. Cinza incubada é mais adequada, pois resultou em maiores valores de produção.

Progenesis QI (PQI) is a multiplatform bioinformatics tool that facilitates the identification workflow for metabolomics experiments. PQI uses fragmentation data provided by MassBank of North America (MoNA) libraries, among others, for metabolite annotation. However, PQI does not officially support MoNA libraries and other libraries based on structure-data files (.sdf). This paper describes the development and application of a software named MoNA to Progenesis QI Library Converter, allowing PQI and MoNA by correcting the fragmentation data of the library for Progenesis readability. We evaluated several public experimental datasets, including human plasma, plant extracts, cultured cells, bacteria, rat serum, and rat hippocampus. The results showed that it is mandatory to proceed with file conversion of each library to allow PQI to access fragmentation information from .msp (main spectra profile) files. This step is highly recommended to improve the identification level of the metabolites.

ABSTRACT Isolated gallbladder perforation due to penetrating abdominal trauma is a rare event due to its anatomical location. The signs and symptoms suggestive of choleperitoneum may not be obvious within the first few hours following the event. This is the case of a 26-year-old man with penetrating abdominal trauma due to bladed weapon used by some individual with isolated gallbladder perforation. Keywords: gallbladder perforation, biliary peritonitis, penetrating abdominal trauma

RESUMEN La perforación vesicular aislada posterior a un traumatismo penetrante de abdomen es un evento infrecuente debido a la situación anatómica de la misma. Los signos y síntomas de un coleperitoneo pueden no ser evidentes en las primeras horas a días del evento. Este es el caso de un paciente de 26 años que, tras traumatismo abdominal por arma blanca por agresión de terceros, presenta perforación aislada de la vesícula biliar.

RESUMO O objetivo foi avaliar o efeito da dose e do manejo de aplicação de cinzas de madeira nos atributos de qualidade do solo em uma área de Cerrado cultivada com Urochloa brizantha. O experimento foi realizado em blocos casualizados, no esquema em faixas 5 × 2 e quatro repetições. As doses de cinzas foram de 0, 8, 16, 24 e 32 t ha-1, e o manejo de aplicação considerou cinza de madeira incorporada e não incorporada ao solo. Os valores de P, K e pH do solo aumentaram com o aumento das doses de cinza de madeira. A densidade do solo diminuiu 9,66% com as doses de cinzas de madeira de 24 e 32 t ha-1 incorporadas ao solo. Devido ao aumento do pH do solo, dose de cinzas de madeira maior que 16 t ha-1 diminuiu a atividade enzimática. Uma dose de cinza de madeira de 24 t ha-1 resultou em melhores condições para o solo, melhorando sua qualidade e contribuindo para o equilíbrio e a dinâmica entre os atributos químicos, físicos e biológicos do solo, o que levou à redução da densidade e maior disponibilidade de P no solo.

ABSTRACT The objective was to evaluate the effect of wood ash dose and application management on soil quality attributes in a Cerrado area cultivated with Urochloa brizantha. The experiment was carried out in a randomized block design in a 5 × 2 strip-plot scheme and four repetitions. The ash doses were 0, 8, 16, 24, and 32 t ha-1, and the application management considered wood ash that is incorporated and not incorporated into the soil. The P, K, and pH values of the soil increased with an increase in the doses of wood ash. The soil bulk density decreased by 9.66% with the wood ash doses of 24 and 32 t ha-1 incorporated into the soil. Owing to an increase in the soil pH, a wood ash dose of greater than 16 t ha-1 decreased the enzymatic activity. A wood ash dose of 24 t ha-1 resulted in better conditions for the soil, improving its quality and contributing to the balance and dynamics between the chemical, physical, and biological attributes of the soil, which led to the reduced density and greater availability of P in the soil.

RESUMO O Brasil não é autossuficiente na produção de trigo (Triticum aestivum L.) e a expansão do cultivo para o cerrado mato-grossense, em sistema irrigado, constitui alternativa para aumentar a produção desse cereal. Assim, objetivou-se avaliar os efeitos das tensões de água no solo no crescimento e na produção de cultivares de trigo sob Oxisol de Cerrado. Os tratamentos foram arranjados em um esquema fatorial 3 × 5, com três cultivares de trigo (BRS 254, BRS 394 e BRS 264) e cinco tensões de água no solo (5, 15, 25, 35 e 45 kPa), usando um delineamento em blocos casualizados, com quatro repetições. O crescimento e produção do trigo mostraram melhor resposta na tensão de 5 kPa. A cultivar BRS 254 apresentou maior redução na produção de espigas e de grãos por espiga com o incremento das tensões de água no solo. Entre as cultivares, a BRS 264 produziu maior número de grãos por espiga nas tensões de 35 e 45 kPa. As cultivares de trigo BRS 254, BRS 394 e BRS 264 possuem alto requerimento de água. Entretanto, a cultivar BRS 264 apresenta maior crescimento e produção em condições de restrição de água no solo, podendo ser cultivada com um sistema de irrigação acionado com menor frequência, com menor gasto de água e energia.

ABSTRACT Brazil is not self-sufficient for the production of wheat (Triticum aestivum L.), and the expansion of cultivation to the Cerrado in the State of Mato Grosso, in an irrigated system, is an alternative solution to increase wheat production. This study aimed to evaluate the effects of soil water tension on the growth and production of wheat cultivars cultivated in the Cerrado Oxisol. The treatments were arranged in a 3 × 5 factorial scheme, with three wheat cultivars (BRS 254, BRS 394, and BRS 264) and five water tensions in soil (5, 15, 25, 35, and 45 kPa), using a randomized block design with four replications. Wheat growth and production exhibited a better response at a tension of 5 kPa. Cultivar BRS 254 showed the lowest production of spikes and grains per spike with increasing soil water tension. Among the cultivars, BRS 264 produced the highest number of grains per spike at tensions of 35 and 45 kPa. The wheat cultivars BRS 254, BRS 394, and BRS 264 have high water requirements. However, BRS 264 presented greater growth and production under conditions of restricted water in the soil, being able to be cultivated with an irrigation system activated less frequently, with less expenditure of water and energy.

ABSTRACT BACKGROUND: Developmental dysplasia of the hip (DDH) encompasses a broad spectrum of hip pathologies, including femoral or acetabular dysplasia, hip instability, or both. According to the medical literature, ultrasonography is the most reliable diagnostic method for DDH. Several techniques for the assessment of hips in newborns and infants, using ultrasonography, have been described. OBJECTIVE: To compare the accuracy of the Graf technique and other diagnostic techniques for DDH. DESIGN AND SETTING: A systematic review of studies that analyzed ultrasound techniques for the diagnosis of DDH within an evidence-based health program of a federal university in São Paulo (SP), Brazil. METHODS: A systematic search of relevant literature was conducted in the PubMed, EMBASE, Cochrane Library, CINAHL, and LILACS databases for articles published up to May 5, 2020, relating to studies evaluating the diagnostic accuracy of different ultrasound techniques for diagnosing DDH. The QUADAS 2 tool was used for methodological quality evaluation. RESULTS: All hips were analyzed using the Graf method as a reference standard. The Morin technique had the highest rate of sensitivity, at 81.12–89.47%. The Suzuki and Stress tests showed 100% specificity. The Harcke technique showed a sensibility of 18.21% and specificity of 99.32%. CONCLUSION: All the techniques demonstrated at least one rate (sensibility and specificity) lower than 90.00% when compared to the Graf method. The Morin technique, as evaluated in this systematic review, is recommended after the Graf method because it has the highest sensitivity, especially with the three-pattern classification of 89.47%. REGISTRATION NUMBER: Identifier: CRD42020189686 at the International Prospective Register of Systematic Reviews (identifier: CRD42020189686).

Objective: Childhood maltreatment (CM) is a significant risk factor for the development and severity of bipolar disorder (BD) with increased risk of suicide attempts (SA). This study evaluated whether a machine learning algorithm could be trained to predict if a patient with BD has a history of CM or previous SA based on brain metabolism measured by positron emission tomography. Methods: Thirty-six euthymic patients diagnosed with BD type I, with and without a history of CM were assessed using the Childhood Trauma Questionnaire. Suicide attempts were assessed through the Mini International Neuropsychiatric Interview (MINI-Plus) and a semi-structured interview. Resting-state positron emission tomography with 18F-fluorodeoxyglucose was conducted, electing only grey matter voxels through the Statistical Parametric Mapping toolbox. Imaging analysis was performed using a supervised machine learning approach following Gaussian Process Classification. Results: Patients were divided into 18 participants with a history of CM and 18 participants without it, along with 18 individuals with previous SA and 18 individuals without such history. The predictions for CM and SA were not significant (accuracy = 41.67%; p = 0.879). Conclusion: Further investigation is needed to improve the accuracy of machine learning, as its predictive qualities could potentially be highly useful in determining histories and possible outcomes of high-risk psychiatric patients.

RESUMO A compactação do solo é um problema recorrente na agricultura, levando à redução da produtividade das culturas. Diante disso, a aplicação de resíduo agroindustrial da queima de biomassa vegetal pode melhorar as propriedades químicas e físicas do solo. O objetivo deste trabalho foi avaliar o crescimento do capim paiaguás sob diferentes densidades do solo e doses de cinzas vegetal. O experimento foi conduzido em blocos casualizados, em esquema fatorial 5 × 5, composto por cinco valores de compactação do solo (1,0, 1,2, 1,4, 1,6 e 1,8 Mg m-3) e cinco doses de cinza vegetal (0, 8, 16, 24, 32 g dm-3), com quatro repetições. Densidades do solo acima de 1,2 Mg m-3 reduzem a massa seca do capim paiaguás. A dose de cinza de madeira de 20,42 g dm-3 apresenta o maior valor de massa seca da parte aérea. O crescimento da raiz é maior na dose de cinza de madeira de 16,52 g dm-3.

ABSTRACT Soil compaction is a recurring problem in agriculture that ultimately leads to a reduction in crop productivity. However, the application of agro-industrial residues from the burning of plant biomass can improve the chemical and physical properties of soil. The objective of this study was to evaluate the growth of Paiaguás grass under different soil densities and wood ash doses. The experiment was carried out in a randomized block design, under a 5 × 5 factorial scheme, with five soil compaction values (1.0, 1.2, 1.4, 1.6, and 1.8 Mg m-3) and five doses of wood ash (0, 8, 16, 24, and 32 g dm-3), with four replicates. A soil density greater than 1.2 Mg m-3 reduced the dry mass of Paiaguás grass. The wood ash dose of 20.42 g dm-3 led to the highest shoot dry mass. Root growth was highest at a wood ash dose of 16.52 g dm-3.

RESUMO A adição de cinza da madeira no solo é uma alternativa para a disposição deste resíduo. Porém, seus efeitos nas propriedades físico-hídricas do solo ainda são divergentes. Neste estudo, avaliou-se o efeito da adição de cinzas vegetal na curva característica da água do solo, água gravitacional, capacidade de campo, água total disponível e condutividade hidráulica saturada em um Oxisol e em um Quartzipsamment. O delineamento experimental foi inteiramente casualizado em esquema fatorial 2 × 4, correspondendo a dois solos e quatro doses de cinza vegetal, com três repetições. A cinza vegetal utilizada é proveniente de agroindústria, resultante da queima da madeira de eucalipto. As doses de cinza vegetal foram de 0, 16, 32 e 64 g dm-3, em Oxisol (40% argila, textura Argila) e em Quartzipsamment (6% argila e textura Areia). A água gravitacional, a capacidade de campo e a água total disponível ajustaram-se ao modelo quadrático em função das doses de cinza de madeira. A condutividade hidráulica saturada reduziu linearmente com a aumento das doses de cinza vegetal para ambas as classes de solo. A curva característica do solo aumentou significativamente (p ≤ 0,05) apenas na dose de 64 g dm-3 de cinza vegetal. O aumento do total de água disponível foi mais evidente no Oxisol do que no Quartzipsamment, com incremento de 64 e 31%, respectivamente, na dose máxima de 64 g dm-3 de cinza vegetal.

ABSTRACT The addition of wood ash to soil is an alternative to disposing of this residue. However, the effects of wood ash on soil physical-hydric properties remain divergent. In this study, the effects of added wood ash on the soil water characteristic curve, gravitational water, field capacity, total available water, and saturated hydraulic conductivity were evaluated in Oxisol (40% clay and clay texture) and Quartzipsamment (6% clay and sand texture). The experimental design was completely randomized in a 2 × 4 factorial scheme, where the factors were two soils and four doses of wood ash, with three replicates. The wood ash came from an agribusiness and was the result of burning eucalyptus wood. The wood ash doses were 0, 16, 32, and 64 g dm-3. The gravitational water, field capacity, and total available water were fitted to a quadratic model as a function of the wood ash dose. The saturated hydraulic conductivity decreased linearly with an increase in wood ash dose for both soil classes. The soil water characteristic curve only increased significantly (p ≤ 0.05) with a wood ash dose of 64 g dm-3. The increase in total available water was more evident in Oxisol than that in Quartzipsamment, with increments of 64 and 31%, respectively, at a maximum dose of 64 g dm-3 of wood ash.