ABSTRACT We describe a case of a 33-years-old woman who presents with severe acute bilateral visual loss secondary to massive exudative hypertensive maculopathy as the first sign of immunoglobulin A nephropathy. The patient’s ophthalmic examination showed bilateral cotton-wool spots, flame-shaped retinal hemorrhages, diffuse narrow arterioles, optic disk edema, and exudative maculopathy. Systemic workup demonstrated a systolic and diastolic blood pressure of 240 mmHg and 160 mmHg, respectively, proteinuria, and hematuria, suggesting kidney disease as the causative condition. A kidney biopsy confirmed immunoglobulin A nephropathy. She was treated with systemic corticosteroids, antihypertensive drugs, and a single bilateral intravitreal injection of aflibercept. There was a prompt resolution of macular edema and vision improvement. Our case draws attention to the fact that severe bilateral visual loss can be the first sign of severe hypertension. Secondary causes, such as immunoglobulin A nephropathy, should be ruled out.

RESUMO Nosso objetivo é descrever uma paciente de 33 anos de idade, com perda visual bilateral grave por maculopatia hipertensiva exsudativa como o primeiro sinal da nefropatia por imunoglobulina A. A fundoscopia revelou a presença de manchas algodonosas, hemorragias em chama-de-vela, estreitamento arteriolar difuso, edema de disco óptico e maculopatia exsudativa bilateral. A pressão arterial sistólica foi de 240mmHg e a diastólica de 160 mmHg associado a proteinúria e hematúria, sugerindo a presença de doença renal. A biópsia renal confirmou a nefropatia por imunoglobulina A. A paciente foi tratada como corticoide sistêmico, drogas anti-hipertensivas e uma única dose intravítrea de Aflibercept em ambos os olhos. Houve rápida melhora do edema macular e da acuidade visual. Nosso caso chama a atenção para o fato de que a perda visual bilateral grave pode ser a primeira apresentação de uma doença hipertensiva sistêmica. Causas secundárias como a nefropatia por imunoglobulina A devem ser afastadas.

RESUMO Nosso objetivo é descrever uma paciente de 33 anos de idade, com perda visual bilateral grave por maculopatia hipertensiva exsudativa como o primeiro sinal da nefropatia por imunoglobulina A. A fundoscopia revelou a presença de manchas algodonosas, hemorragias em chama-de-vela, estreitamento arteriolar difuso, edema de disco óptico e maculopatia exsudativa bilateral. A pressão arterial sistólica foi de 240mmHg e a diastólica de 160 mmHg associado a proteinúria e hematúria, sugerindo a presença de doença renal. A biópsia renal confirmou a nefropatia por imunoglobulina A. A paciente foi tratada como corticoide sistêmico, drogas anti-hipertensivas e uma única dose intravítrea de Aflibercept em ambos os olhos. Houve rápida melhora do edema macular e da acuidade visual. Nosso caso chama a atenção para o fato de que a perda visual bilateral grave pode ser a primeira apresentação de uma doença hipertensiva sistêmica. Causas secundárias como a nefropatia por imunoglobulina A devem ser afastadas.

ABSTRACT We describe a case of a 33-years-old woman who presents with severe acute bilateral visual loss secondary to massive exudative hypertensive maculopathy as the first sign of immunoglobulin A nephropathy. The patient’s ophthalmic examination showed bilateral cotton-wool spots, flame-shaped retinal hemorrhages, diffuse narrow arterioles, optic disk edema, and exudative maculopathy. Systemic workup demonstrated a systolic and diastolic blood pressure of 240 mmHg and 160 mmHg, respectively, proteinuria, and hematuria, suggesting kidney disease as the causative condition. A kidney biopsy confirmed immunoglobulin A nephropathy. She was treated with systemic corticosteroids, antihypertensive drugs, and a single bilateral intravitreal injection of aflibercept. There was a prompt resolution of macular edema and vision improvement. Our case draws attention to the fact that severe bilateral visual loss can be the first sign of severe hypertension. Secondary causes, such as immunoglobulin A nephropathy, should be ruled out.

Abstract The suckling behavior of piglets was evaluated in summer and winter, using 21 sows of the same genetic line. Data were collected in July (winter) and in January (summer). The experimental design was a randomized complete block (age of piglets) in a 2x2 factorial scheme, with season of the year (winter and summer) and shift (day, from 06 h to 1h:59min and night from 18h to 05h:59min) as factors. The behavioral variables analyzed were number, interval, and frequency of suckling. The behaviors were monitored on day 7 and 15 of lactation, for 24 hours. In winter, the farrowing room had a mean temperature of 20.32 ±2.17°C and a relative humidity (RH) of 58.63 ±2.99%. In the summer, the mean temperature was 26.65 ±4.02°C, with an RH of 62.22 ±12.06%. During winter, the piglets presented longer sucklings during the night, dedicating 1.84 minutes more to suckling compared to the daytime. Nighttime sucklings were 3.13 minutes longer in winter than in summer. However, in summer, piglets suckled more often during the night, with greater interval between feeds during the day. Based on our results, the season influences the suckling behavior of piglets, with shorter feedings and greater frequencies in summer.

Abstract The objective of this trial was to evaluate the behavioral patterns and performance of lactating sows and their litters under the effect of artificial vocalization. Twenty-eight sows and their litters were distributed in a completely randomized design in a 2x2 factorial scheme (artificial vocalization x lactation week). The behavior of the animals was monitored during 24 hours on the 7th and 15th days of lactation, analyzing the number, interval, and frequency of nursings. The body condition and performance of the sows were also evaluated. Artificial vocalization promoted higher frequencies of eating for sow and nursing for piglets (P <0.05), increased inactive sow behavior (P <0.05), and reduced sow alert in activity (P <0.05). The number and duration of suckling sessions at the 15thday of lactation were reduced (P <0.05). The use of artificial vocalization did not affect the body condition or milk production of the lactating sows, or the performance of the litter during lactation (P> 0.05). The use of maternal artificial vocalization during lactation of sows promoted greater lactation efficiency and longer rest time, favoring the sows’ welfare.

ABSTRACT Physiological parameters such as respiratory frequency and rectal temperature stand out as indicators for heat stress in pigs, however, requiring time and labor for measurements. The possibility of using infrared thermography associated with prediction systems of these physiological variables can help in decision making, allowing greater welfare and productivity of the animals. With this objective, an experiment was carried out with growing pigs submitted to acute and chronic heat stress, working with a thermoneutrality temperature (22° C) and heat stress (34° C). The results were used for the development of a fuzzy model using as input variables: air dry bulb temperature (°C), average surface temperature (°C) and, as output variables: respiratory frequency (movements/minute) and rectal temperature (°C). The method of inference used was the one of Mamdani having been elaborated six rules and the defuzzification technique used was the one of the Center of Gravity. In the obtained results on simulation model when compared with experimental data was evidenced satisfactory efficiency in respiratory frequency determination and the rectal temperature, in which the R2 values calculated were respectively 0.997 and 0.951 for acute stress and 0.993 and 0.964 for chronic heat stress.

Abstract In order to inhibit natural gas hydrate formation, monoethyleneglycol (MEG) is usually injected into producing well heads. The MEG regeneration process is continuously performed at the platform. Scaling problems usually occur due to the presence of chlorides and carbonates. This work presents salt solubility data for the aqueous system with strontium carbonate, MEG and carbon dioxide. A specific analytical method was developed. Thus, experimental data for strontium carbonate (SrCO3) solubility at various carbon dioxide pressures are reported. Solubilities of SrCO3 in water were measured from 760 to 1610 mmHg at 278.15. 288.15. 298.15 and 323.15 K. For the mixed solvent (ms) conditions, solubilities were measured at 298.15 K and four isobars, i.e., 760, 1210, 1410 and 1520 mmHg. Experimental data were correlated and demonstrated to be accurate for thermodynamic modeling and process simulation.

Este trabalho teve o objetivo de avaliar o ambiente térmico e o ruído em celas de maternidade para suínos com divisórias de alvenaria ou com rochas de ardósia. Para as medidas das variáveis de conforto térmico e de ruídos, utilizaram-se de termômetros e decibelímetro. No interior das celas e para a análise estatística, foram usados doze matrizes e cento e trinta e nove leitões, distribuídos em delineamento em blocos casualizados, em esquema de parcelas subdivididas. Os resultados mostraram que, no período da manhã, em ambos os tratamentos, as condições de conforto térmico foram mais adequadas para as matrizes, enquanto no período da tarde, mais adequadas para os leitões; com relação ao ruído, este foi menor nas celas de alvenaria. De forma geral, o ambiente no interior das celas construídas em ardósia apresentou umidade relativa mais baixa, e ITGU e temperatura mais elevada que as celas construídas em alvenaria. O nível de ruídos permaneceu dentro dos limites considerados ideais para suínos em ambos os tratamentos.

The aim of the present study was to evaluate the thermal environment and noise levels in swine farrowing cells built with masonry or slate. Thermometers and sound level meter equipment were used to measure the thermal comfort variables. Inside the cells and for the statistical analysis, twelve sows and one hundred thirty-nine piglets were used, distributed in a randomized blocks design in a split-plot arrangement. The results showed that in the morning, in both treatments, the thermal comfort conditions were more suitable for sows, while in the afternoon it was more suitable for piglets. The noise was lower in the masonry cells. Overall, the environment inside in the cells built with slate presented lower relative humidity and, higher BGHI and temperature than those built with masonry. The noise level remained within the thresholds considered as ideal for swine in both treatments.

Foi conduzido um experimento para avaliar o comportamento, desempenho e parâmetros fisiológicos de suínos, em diferentes sistemas de produção. Foram utilizados 24 suínos em crescimento, distribuídos em delineamento casualizado, nos tratamentos: T1 - piso de concreto; T2 - cama sobreposta com maravalha; T3 - cama sobreposta com casca de café. Realizou-se observação do comportamento animal, por oito horas ininterruptas, ao longo de sete semanas. Foram caracterizadas as proporções de tempo dedicadas a cada comportamento, utilizando a composição de histograma de frequência. Foram mensurados parâmetros ambientais (ITGU), fisiológicos (temperatura retal e de superfície e frequência respiratória) e de desempenho dos animais (ganho de peso, consumo de ração e conversão alimentar) durante o período. Os sistemas de produção sobre cama proporcionaram maiores valores de ITGU. Não houve efeito dos sistemas avaliados sobre os parâmetros de desempenho. A temperatura retal foi superior nos animais criados sobre cama de casca de café, em relação ao piso de concreto. O uso de camas sobrepostas beneficiou o comportamento de leitões em fase de crescimento e reduziu o comportamento agonístico entre indivíduos.

An experiment was conducted to evaluate the behavior, performance and physiological parameters of pigs in different production systems. Twenty four animals in the growth phase were distributed in a randomized block design in three treatments: T1 - concrete floor, T2 - deep bedding with wood shaving, and T3 - deep bedding with coffee husks. The behavioral study was carried out by observing the animal behavior for an uninterrupted period of eight hours throughout seven weeks. The proportions of time spent in each behavior were characterized using the frequency histogram composition. Environmental (IBGTH), physiological (rectal and skin temperature and respiratory rate) and performance (weight gain, feed intake and feed conversion) parameters were measured in animals during the period. The production systems of deep bedding showed higher values of IBGTH. There was no effect of production systems evaluated on the performance parameters. Rectal temperature was higher in animals reared on deep bedding with coffee husks in relation to the concrete floor. The use of deep bedding benefited the behavior of piglets in the growth phase and it reduced the agonistic behavior among individuals.

O presente trabalho teve o objetivo de avaliar o uso da ardósia na construção de celas de maternidade, sendo monitoradas 12 matrizes e 139 leitões em celas confeccionadas de alvenaria e ardósia (tratamentos). Imagens digitais foram avaliadas por meio de dois etogramas. As variáveis ambientais foram registradas às 9 h e 15 h. O desempenho dos leitões foi determinado pelo peso ao nascimento e à desmama, ganho de peso diário e final. Na cela de alvenaria, os leitões passaram menos tempo mamando (25,62%) e mais no escamoteador (38,91%) que aqueles mantidos na cela de ardósia (29,22% mamando e 24,90% no escamoteador). As variáveis ambientais e os índices de conforto mostraram que o microclima na cela de ardósia apresentou-se mais confortável aos leitões, enquanto aquele em alvenaria foi mais confortável às matrizes. Os leitões mantidos nas celas de alvenaria apresentaram ganho de peso diário semelhante aos alojados em celas de ardósia (P<0,05). Os comportamentos das matrizes foram semelhantes em ambos os tipos de cela, apresentando maior frequência do comportamento "deitado". A ardósia pode ser uma alternativa vantajosa à alvenaria na construção de celas no setor de maternidade para suínos, por apresentar maior impermeabilidade, facilidade de limpeza e desinfecção.

It was aimed with the present study to evaluate the use of slate in the construction of farrowing stalls. Twelve sows and one hundred thirty nine piglets were monitored in cell built with masonry and slate (treatments). Digital images were evaluated through two ethogram. The environmental variants were evaluated at 9 am and 3 pm. The piglets' performance was determinated by birth and weaning weights, and daily and final weight gains. At the masonry cell the piglets spent less time nursing (25.62%) and more in the creep (38.91%) than those kept in the slate cell (29.22% nursing and 24.90% in the creep). And the environmental variants and comfort index showed that the microclimate into the slate cell was more comfortable to piglets, while that around the masonry was more comfortable to sows. The piglets kept in the masonry cell presented daily weight gain similar to the ones housed in the slate cell (P <0.05). The sows' behaviors were similar in both types of cell, showing higher frequency of the "laying" behavior. Slate can be an advantageous alternative to masonry construction of cell in the field of farrowing housing for swine, due to its higher impermeability, easy for cleaning and disinfection.