Abstract This study aimed to evidence the validity and reliability ofthe Ecuadorian version ofthe Adult Dispositional Hope Scale, one of the most studied concepts of positive psychology. The adaptation process included translation and semantic and idiomatic validation. For content validation, an expert review and focus group were conducted. The questionnaire was applied to 2423 workers in Ecuador with a mean age of 37 years (SD = 9.04), and 65.6% were women. A confirmatory factor analysis was conducted to assess the validity of the scale’s dimensionality. The reliability and convergent and discriminant validity were also evaluated. In order to investigate the best solution for an Ecuadorian version ofthe Adult Dispositional Hope Scale, four structural models were assessed. The unidimensional solution was the most adequate structure for the scale. The internal consistency of the scale was adequate. The Adult Dispositional Hope Scale (ADHS) was developed to assess this positive psychological state and has been the most used tool in many contexts. To our knowledge, this study is the first to adapt the Adult Dispositional Hope Scale into the Ecuadorian context and evaluate its validity. The findings support its reliability, factorial, and construct validity in the Ecuadorian context. Furthermore, the results show that dispositional hope acts as a protective factor, promoting work engagement and preventing burnout.

ABSTRACT Paracoccidioides species cause paracoccidioidomycosis (PCM), a systemic mycosis highly prevalent in Brazil. Therapy of PCM has some issues that make studies for new therapeutic and vaccine targets relevant, such as the P. brasiliensis 60-kDa-heat-shock protein (PbHsp60), an immunogenic antigen that induces protection in experimental mice infection. Here, we investigated the relative expression of mRNA for PbHsp60 in P. brasiliensis in the different morphotypes of P. brasiliensis and in morphological transition phases. In addition, antibodies to rPbHsp60 were produced and used to analyze the location of PbHsp60 in yeast and hyphae by electron microscopy. The analyses showed a substantial increase in the relative amounts of HSP60 mRNA in yeast when compared to mycelium and an intermediate expression in transitional forms. Regarding the cell location, immunoelectron microscopy analysis revealed that PbHsp60 is within the cell wall. These observations suggest that this protein may be involved in the maintenance of the cell wall integrity and the interaction with the host for colonization, infection and pathogenesis.

RESUMO Objetivo: Investigar o papel mediador do flow no trabalho entre as relações das dimensões de redesenho no trabalho (redesenho da tarefa, reformulação cognitiva e redesenho das relações) com as dimensões de saúde mental positiva (bem-estar emocional, bem-estar psicológico e bem-estar social). Originalidade/valor: As ações de redesenho no trabalho têm sido valorizadas como antecedentes do bem-estar laboral dos profissionais. O presente estudo contribuiu para a literatura ao examinar as relações entre as ações de redesenho no trabalho, o flow no trabalho e a saúde mental positiva, ainda não investigadas em trabalhos empíricos prévios. Design/metodologia/abordagem: Utilizou-se a abordagem quantitativa por meio de um questionário on-line composto por questionário sociodemográfico e três escalas. A amostra foi composta por 386 profissionais de diferentes estados brasileiros, sendo 58% do gênero feminino, com idade média de 44 anos (DP = 12 anos). Os dados foram analisados por meio de equações estruturais. Resultados: Os resultados das análises de equações estruturais demonstraram que o redesenho das relações apresentou um impacto direto sobre a saúde mental positiva. As relações da reformulação cognitiva com a saúde mental positiva foram totalmente mediadas pelos níveis de flow no trabalho. Conclui-se que as ações de redesenho do trabalho, primordialmente a reformulação cognitiva, influenciam o bem-estar laboral e geral.

ABSTRACT Purpose: To investigate the mediating role of flow at work on the relations of job crafting (task crafting, cognitive crafting and relational crafting) with positive mental health dimensions (emotional well-being, psychological well-being and social well-being). Originality/value: Job crafting actions have been identified as antecedents of the levels of well-being at work. The present study contributed to the literature examining the relationships between job crafting, flow at work, and positive mental health, which have not yet been investigated in previous empirical studies. Design/methodology/approach: The quantitative approach was used through an online questionnaire composed of a sociodemographic questionnaire and three scales. The sample consisted of 386 professionals from different Brazilian states, of which 58% were female, with a mean age of 44 years (SD = 12 years). The data were analyzed through structural equations. Findings: The results of the analysis of structural equations showed that relational crafting had a direct impact on positive mental health. The relations of cognitive crafting with positive mental health were totally mediated by flow at work. We concluded that job crafting, primarily cognitive crafting, influence occupational and general well-being.

RESUMO Objetivo Determinar se o protocolo original da Terapia por Contensão Induzida (TCI), é adequado para reverter o não uso do membro superior afetado (MSA) em pacientes com Paralisia Cerebral (PC) na fase adulta. Método Foram incluídos no estudo 10 pacientes com diagnóstico de PC hemiparéticos que haviam realizado o protocolo adulto da TCI, no período de janeiro/2009 a agosto/2014. Resultados Média de idade 24,6 (DP 9,44); MAL média pré-tratamento Quantidade (QT) = 0,72 e Qualidade (QL) = 0,68 e no pós-tratamento QT = 3,77 e QL = 3,60 (p ≤ 0,001) e WMFT média pré-tratamento = 21,03 e média pós-tratamento = 18,91 (p = 0,350). Conclusão A terapia por contensão induzida é eficaz para reverter o não uso do MSA em pacientes adultos com PC.

ABSTRACT Objective To determine if the original protocol of Constraint-Induced Movement Therapy (CIMT), is adequate to reverse the nonuse of the affected upper limb (AUL) in patients with Cerebral Palsy (CP) in adulthood. Method The study included 10 patients diagnosed with CP hemiparesis had attended the adult protocol CIMT, from January/August 2009/2014. Results Average age 24.6 (SD 9.44); MAL average pretreatment How Often (HO) = 0.72 and How Well (HW) = 0.68 and post-treatment HO = 3.77 and HW = 3.60 (p ≤ 0.001) and pretreatment WMFT average = 21.03 and post-treatment average = 18.91 (p = 0.350). Conclusion The constraint-induced movement therapy is effective to reverse the nonuse learn of the AUL in adult patients with CP.

A síndrome de Chédiak-Higashi é uma doença hematológica rara caracterizada pelo aumento da fusão dos grânulos citoplasmáticos. Manifestações neurológicas ocorrem em cerca de metade dos pacientes. Relatamos o caso de uma criança com síndrome de Chédiak-Higashi e crises convulsivas.

Chédiak-Higashi syndrome is a rare hematological disease characterized by increased fusion of cytoplasmatic granules. Neurological symptoms occur in approximately half of the patients. We describe the clinical, eletrophysiological, hematological and radiological findings in a girl who had Chédiak-Higashi syndrome and seizures.