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COVID-19 Associated Mucormycosis with Newly Diagnosed Diabetes Mellitus in Young Males - A Tertiary Care Experience
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Kapoor, Sahil

; Saidha, Poonam Kumar

; Gupta, Ayushi

; Saini, Urvi

; Satya, Sneha

International Archives of Otorhinolaryngology

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Set 2022, Volume 26 Nº 3 Páginas 470 - 477

Resumo: En | Texto: En | PDF: En

Abstract Introduction Patients with a history of or active COVID-19 infection are predisposed to the development of opportunist bacterial and fungal infections. A rising incidence of a rare occurring fungal infection earlier, called mucormycosis, has been reported in abundance across the globe since March 2021, especially in India just as the second wave of COVID-19 began, caused by the trifecta of hyperglycemia (new-onset or exacerbation of pre-existing diabetes), oxygen therapy (invasive or noninvasive ventilation), and prolonged intake of steroids. Objective The present study aimed at assessing the prevalence of post-COVID mucormycosis in males of younger age group and spread of rhino-orbital-cerebral mucormycosis (ROCM). Methods A case-control study was performed over a period of 3 months among 60 male patients with confirmed diagnosis of mucormycosis. Individuals < 40 years old were included in the case group (n = 30), while those > 40 years old were included as controls (n = 30). Disease spread was assessed in three types of ROCM, that is, rhinomaxillary, rhino-orbital, and rhino-orbito-cerebral mucormycosis. Results In the control group, the mean age was 48.47 years old, the mean HbA1c was 10.62 ± 1.88%, with most of them suffering from rhino-orbital mucormycosis. In the case group, the mean age was 31.57 years old, with a mean HbA1c of 10.11 ± 2.46%, and most patients had rhinomaxillary mucormycosis. The duration of steroid intake and mode of oxygen therapy were found to be significant in the severity of ROCM. Conclusion Rising cases of post-COVID mucormycosis have brought to light the fatal consequences of prolonged use of steroids and oxygen therapy towards the development and spread of ROCM among young and middle-aged males.

https://doi.org/10.1055/s-0042-1748927

Cervical Thymic Cyst with parathyroid tissue – a diagnostic conundrum
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Gupta, Deepika

; Kaushal, Darwin

; Vedant, Deepak

; Sharma, Rashim

; Vishwajeet, Vikarn

; Elhence, Poonam Abhay

Autopsy and Case Reports

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2022, Volume 12 elocation e2021361

Resumo: En | Texto: En | PDF: En

ABSTRACT Cervical thymic cysts are relatively rare benign cystic lesions that tend to be diagnosed clinically as branchial cysts, which usually present as painless, enlarging neck masses. They can occur anywhere along the normal path of descent of thymic primordia from the angle of the mandible to the sternal notch, with mediastinal extension observed in approximately 50% of cases. They are usually seen in the first decade of life on the left side with a male predominance. Here we report a case of a 15-year-old boy who presented to the hospital with left-sided neck swelling for about 2 months. The neck’s contrast-enhanced computed tomography (CECT) revealed a large, well-defined cystic swelling in the left neck region, showing peripheral enhancement, seen from the submandibular region to the superior mediastinum extending into the retrosternal region. Direct fine needle aspiration (FNA) was done, which showed a benign lesion with inflammatory and cystic characteristics, leading to the possibility of a branchial cyst. The cyst was completely excised surgically. Histopathology showed a thymic cyst with parathyroid tissue. The presence of thymic tissue with Hassall’s corpuscles is essential for the diagnosis. Knowledge of the clinical presentation, cyto-histological findings, and differential diagnosis of cystic cervical lesions in the pediatric population is important to diagnose this rare entity. Hence, though uncommon, when one comes across a cystic cervical region mass in children, a diagnosis of cervical thymic cyst should be kept in mind. Nonetheless, a definitive diagnosis depends on imaging findings as well as intraoperative findings and histopathological examination.

https://doi.org/10.4322/acr.2021.361

SPECIAL ARTICLE COVID-19: Ear, Nose, and Throat Practice Guidelines: An Update for COVID-19
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Kapoor, Sahil

; Gupta, Ayushi

; Saidha, Poonam Kumar

International Archives of Otorhinolaryngology

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Dez 2021, Volume 25 Nº 4 Páginas 621 - 627

Resumo: En | Texto: En | PDF: En

Abstract Introduction Amidst another wave of COVID-19, the alarming number of cases per day in India has affected the healthcare system and professionals tremendously. As the disease burden continues to increase, ear, nose, and throat (ENT) specialists remain at high risk of exposure to this aerosol borne virus. This requires the creation and regulation of protocols for conducting routine clinical practice, especially by ENT specialists. Objectives To review the available literature and to propose strategies and recommendations for ENT practitioners to conduct their regular practice amidst this pandemic. Data synthesis A systematic review of the available literature on ENT practice during the COVID-19 pandemic was done. Out of the many protocols proposed in various studies, the most practical and feasible ones that could be adopted by practicing ENT doctors/ surgeons in the long run were selected. Adequate precautions and use of high level of personal protective equipment (PPE) is required to be adopted by all practicing ENT doctors. Use of teleconsultation has been promoted as it limits face-to-face exposure. Proper guidelines should be followed for both emergency and elective surgeries. Endoscopy can be used as a safe and useful tool for ENT examination. Conclusion As practicing otorhinolaryngologists, it is of utmost importance that we take all necessary precautions and adopt safety measures in our clinical practice while conducting out patient department (OPD) consultations, operative procedures, and emergency care to protect our patients, ourselves, and other healthcare staff during this time.

https://doi.org/10.1055/s-0041-1736424 1 downloads

A Novel Deep Learning-based Whale Optimization Algorithm for Prediction of Breast Cancer
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Rana, Poonam

; Gupta, Pradeep Kumar

; Sharma, Vineet

Brazilian Archives of Biology and Technology

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2021, Volume 64 elocation e21200221

Resumo: En | Texto: En | PDF: En

HIGHLIGHTS Novel whale optimization algorithm is proposed for prediction of breast cancer. Deep learning-based WOA adjusts the CNN structure as per maximum detection accuracy. Proposed method achieves 92.4% accuracy in comparison to 90.3%. Validity of method is evaluated with magnifying factors like 40x, 100 x, 200x, 400x.

https://doi.org/10.1590/1678-4324-2021200221 509 downloads

Epithelioid angiomyolipoma with tumor thrombus in IVC and right atrium
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Gupta, Deepika

; Vishwajeet, Vikarn

; Pandey, Himanshu

; Singh, Mahendra

; Sureka, Binit

; Elhence, Poonam

Autopsy and Case Reports

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2020, Volume 10 Nº 4 elocation e2020190

Resumo: En | Texto: En | PDF: En

ABSTRACT Epithelioid angiomyolipoma is an uncommon subtype of renal angiomyolipoma associated with potentially malignant behavior and is considered a distinct entity by the World Health Organization classification of renal tumors. We present a case of an epithelioid variant of angiomyolipoma with extension into the renal vein, inferior vena cava reaching up to the right atrium. Pre-operatively, a diagnosis of renal cell carcinoma was considered based on imaging findings. Intra-operatively due to extensive adhesions, surgical resection was not performed and only tissue sampling was performed for histopathology. Microscopic examination revealed short fascicles of spindle cells and perivascular epithelioid cells. A differential diagnosis of renal cell carcinoma with sarcomatoid differentiation was considered. The immunohistochemical profile showed tumor cells that express Melan-A and smooth muscle actin, while they were negative for pan-cytokeratin, PAX8, CK7, CD117 and CD34. Therefore a diagnosis of epithelioid angiomyolipoma was rendered. The presence of intravascular thrombi on radiological investigation and carcinoma-like growth pattern on light microscopy may compound an erroneous diagnosis of renal cell carcinoma. Hence, it is prudent for the urologist to consider differential diagnosis other than renal cell carcinoma when confronted with a renal neoplasm presenting with intravascular thrombi. In these cases, a core biopsy should be planned pre-operatively and diagnosis should be made with aid of appropriate immunohistochemical markers.

https://doi.org/10.4322/acr.2020.190 207 downloads

DBW222 (Karan Narendra): A new high-yielding, lodging-tolerant wheat variety for North Western plains of India
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Mishra, Chandra Nath

; Tiwari, Vinod

; Khan, Hanif

; Kumar, Satish

; Sharma, Amit Kumar

; Singh, Rajender

; Jasrotia, Poonam

; Mamrutha, Harohalli Masthigowda

; Kashyap, Prem Lal

; Gupta, Arun

; Gupta, Vikas

; Gopalareddy, Krishnappa

; Venkatesh, Karnam

; Singh, Charan

; Singh, Sanjay Kumar

; Kumar, Raj

; Tyagi, Bhudeva Singh

; Bhardwaj, Subash Chander

; Chatrath, Ravish

; Prakash, Om

; Lal, Madan

; Singh, Gyanendra

; Singh, Gyanendra Pratap

Crop Breeding and Applied Biotechnology

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2020, Volume 20 Nº 3 elocation e32902037

Resumo: En | Texto: En | PDF: En

Abstract DBW222 is characterized by potential yield of 8210 kg ha-1 under high fertility when sown in timely conditions in North India. It possesses better agronomic attributes and has better adaption to sowing time, high rust resistance, quality attributes, and lodging tolerance because of a shorter 2nd internode and wider diameter.

https://doi.org/10.1590/1984-70332020v20n3c41 2688 downloads

Cricoid and cervical osteophytes causing dysphagia: an extremely rare and interesting case
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Gupta, Puneet

; Mahajan, Manik

; Sharma, Poonam

; Khurana, Arti

; Bhasin, Indu

Radiologia Brasileira

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Fev 2018, Volume 51 Nº 1 Páginas 67 - 68

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1590/0100-3984.2016.0100 3346 downloads

Giant nontraumatic intradiploic arachnoid cyst in a young male
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Sharma, Rajesh

; Gupta, Puneet

; Mahajan, Manik

; Sharma, Poonam

; Gupta, Anchal

; Khurana, Arti

Radiologia Brasileira

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Out 2016, Volume 49 Nº 5 Páginas 337 - 339

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Cistos aracnóideos intradiploicos foram raramente relatados na literatura, sendo a maior parte desses casos decorrente de traumas. Cistos aracnóideos não traumáticos são muito raros e têm sido relatados principalmente em adultos. Aqui, relatamos o caso de um jovem de 16 anos de idade apresentando uma massa de crescimento lento na região occipital e dores de cabeça intermitentes. Com base nos resultados de radiografia, tomografia computadorizada e ressonância magnética da cabeça, a massa foi diagnosticada como um cisto aracnóideo intradiploico gigante.

Abstract Intradiploic arachnoid cysts have scarcely been reported in the literature, most reported cases being secondary to trauma. Nontraumatic arachnoid cysts are quite rare and have been reported mostly in adults. Here, we report the case of a 16-year-old male presenting with a slowly growing mass in the occipital region and intermittent headaches. On the basis of the findings of X-rays, computed tomography scans, and magnetic resonance imaging scans of the head, the mass was diagnosed as a giant intradiploic arachnoid cyst.

https://doi.org/10.1590/0100-3984.2013.0022 1572 downloads

Primary anterior parietal wall abscess due to Salmonella Typhi
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Thakur, Kamlesh

; Singh, Gagandeep

; Gupta, Poonam

; Chauhan, Smriti

; Jaryal, Subhash Chand

Brazilian Journal of Infectious Diseases

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Ago 2010, Volume 14 Nº 4 Páginas 328 - 329

Resumo: En | Texto: En | PDF: En

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