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Expresión de ACE2 en cerebro durante el desarrollo y susceptibilidad de infección cerebral por SARS-COV-2
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Martínez-Morga, Marta

; Hernandez-Lopez, Jose Manuel

; Hernandez-Medina, Cristina

; Martínez-Morga, Salvador

; Martínez, Salvador

Medicina (Buenos Aires)

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Abr 2023, Volume 83 Supl. 2 Páginas 2 - 5

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen La pandemia COVID-19 se extendió por todo por a la enorme capacidad del coronavirus SARS-CoV-2 para transmitirse entre humanos. El COVID-19 es una amenaza para la salud pública mundial. La entrada de este virus en las células se ve muy facilitada por la presencia de la enzima convertidora de angiotensina 2 (ACE2) en la membrana celular. Hoy en día no tenemos un conocimiento preciso de cómo se expresa este receptor en el cerebro durante el desarrollo humano y, como consecuencia, no sabemos si las células neurales en desarrollo son susceptibles de ser infectadas a través de la transmisión de madre a feto. Revisamos en este artículo los conocimientos sobre la expresión de ACE2 en el cerebro humano en desarrollo, con especial atención a la etapa fetal. Esta etapa corresponde al periodo de formación de la corteza cerebral. La posibilidad de infección por SARS-CoV-2 durante el periodo fetal puede alterar el desarrollo normal de la corteza cerebral. Así pues, aunque se han publicado pocos casos demostrando la transmisión vertical de la infección por SARS-CoV-2, el gran número de jóvenes infectados puede representar un problema sanitario que necesite seguimiento, por la posibilidad de que se originen alteraciones cognitivas y anomalías en el desarrollo de los circuitos corticales, que pueden representar predisposición a padecer problemas mentales a lo largo de la vida.

Abstract The COVID-19 pandemic spread around the world due to the enormous transmission of the SARS-CoV-2 among humans. COVID-19 represents a threat to global public health. The entry of this virus into cells is greatly facilitated by the presence of angiotensin-converting enzyme 2 (ACE2) in the cell membrane. Today we do not have a precise understanding of how this receptor expresses in the brain during human development and, as a consequence, we do not know whether neural cells in the developing brain are susceptible to infection. We review the knowledge about ACE2 expression in the developing human brain, with special attention to the fetal stage. This stage corresponds to the period of the cerebral cortex formation. Therefore, SARS-CoV-2 infection during the fetal period may alter the normal development of the cerebral cortex. Although few cases have been published demonstrating vertical transmission of SARS-CoV-2 infection, the large number of infected young people may represent a problem which requires health surveillance, due to the possibility of cognitive alterations and abnormalities in the development of cortical circuits that may represent a predisposition to mental problems later in life.

Dominant Logic and External Collaboration: Determinants of Innovation in An Emerging Economy and A Developed Country
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Donado, Alexandra

; Hernandez, Lina

; Alvear, Carlos

; Castro, Ignacio

Journal of technology management & innovation

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2023, Volume 18 Nº 1 Páginas 67 - 82

Resumo: En | Texto: En | PDF: En

Abstract: From the cognitive perspective and focusing on external collaboration, this study aims to show their contribution to innovative performance, which usually differs between emerging and advanced economies. Databases on Science, Technology and Innovation activities of the countries studied are used, together with CFA and SEM, to validate the hypotheses. It is found that dominant logic and external collaboration enjoy a positive relationship with innovative performance. In Spain, the returns of research and development are greater. This may be due to the fact that cognitive aspects are determinant of leveraging collaborative networks, while in Colombia this needs to be strengthened. In addition to contributing theoretically to the operationalisation of dominant logic and external collaboration in innovative performance, this research contributes to the literature by proposing relationships among the factors studied, providing insights into their influence in the innovation process in a developed and an emerging country, which has not been addressed before.

Trends in overweight and obesity in children under 24 months of age in Mexico (2012-2020): analysis of four national health surveys
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Cárdenas-Villarreal, Velia Margarita

; Hernandez-Barrera, Lucia

; Castro-Sifuentes, Danilo

; Guevara-Valtier, Milton Carlos

; Trejo-Valdivia, Belem

Cadernos de Saúde Pública

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2023, Volume 39 Nº 12 elocation e00046123

Resumo: Es Pt En | Texto: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen: La prevalencia de la obesidad infantil ha aumentado rápidamente en México, y tiene consecuencias para la salud de la población en el futuro. Poco se sabe sobre la prevalencia de obesidad en niños que tienen menos de dos años, etapa fundamental para la prevención de esta condición. El objetivo fue determinar la magnitud, la distribución y las tendencias de sobrepeso y obesidad en niños menores de 24 meses de edad utilizando las Encuestas Nacionales de Salud y Nutrición (ENSANUT) en México en los últimos 10 años. Los datos presentados se derivan de cuatro ENSANUTs en México: 2012, 2016, 2018 y 2020. Los datos incluyen 6.719 menores de 24 meses de edad con datos antropométricos completos (peso/altura) por edad, sexo, etnicidad, lugar de residencia y nivel socioeconómico. Se calculó el riesgo de sobrepeso y sobrepeso + obesidad siguiendo las directrices de la Organización Mundial de la Salud. Se identificó que los menores de 12 meses tienen una prevalencia más alta de sobrepeso + obesidad (10,3%), y los que tienen entre 12 y 23 meses tienen riesgo de sobrepeso más alto (26,1%). Los hallazgos más relevantes por sexo, región, nivel socioeconómico y etnicidad de este estudio que las prevalencias de sobrepeso y obesidad varían en la población mexicana, sin presentar un comportamiento específico. Hay una alta prevalencia de sobrepeso y obesidad en niños mexicanos, y una ligera tendencia de aumento de obesidad en menores de 12 meses. El monitoreo del peso y las intervenciones de prevención de obesidad centradas en los primeros 1.000 días de vida son esenciales.

Resumo: A prevalência da obesidade infantil tem aumentado rapidamente no México, com consequências para a saúde da população no futuro. Pouco se sabe sobre a prevalência de obesidade em crianças menores de dois anos de idade, etapa fundamental para a prevenção desta condição. Nosso objetivo foi determinar a magnitude, distribuição e tendências de sobrepeso e obesidade em crianças menores de 24 meses de idade usando as Pesquisas Nacionais de Saúde e Nutrição (ENSANUT) no México nos últimos 10 anos. Os dados apresentados são derivados de quatro ENSANUTs no México: 2012, 2016, 2018 e 2020. Os dados incluem 6.719 crianças menores de 24 meses e seus dados antropométricos completos (peso/altura) por idade, sexo, etnicidade, área de residência e nível socioeconômico. O risco de sobrepeso e sobrepeso + obesidade foram calculados seguindo as diretrizes da Organização Mundial da Saúde. Foi identificado que crianças menores de 12 meses atualmente têm uma prevalência maior de sobrepeso + obesidade (10,3%), e aqueles com idade de 12 a 23 meses têm mais risco de sobrepeso (26,1%). Os achados mais relevantes por sexo, região, nível socioeconômico e etnicidade deste estudo mostram um México heterogêneo em relação a sobrepeso e obesidade sem apresentar um comportamento específico. Há uma alta prevalência de sobrepeso e obesidade em bebês mexicanos, e uma leve tendência de aumento da obesidade em crianças menores de 12 meses. O monitoramento do peso e as intervenções de prevenção de obesidade focadas nos primeiros 1.000 dias de vida são essenciais.

Abstract: The prevalence of childhood obesity has increased rapidly in Mexico, with significant consequences for the population’s health in the future. Little is known about the prevalence of obesity in children under two years of age, even though this life stage is fundamental to prevent this condition. This study aims to determine the magnitude, distribution, and trends of overweight and obesity in children under 24 months of age using the Mexican National Health and Nutrition Surveys (ENSANUT) conducted in the last 10 years. The data presented here are derived from four ENSANUTs, carried out in Mexico in 2012, 2016, 2018, and 2020. They include 6,719 infants under 24 months with complete anthropometric data (weight/height) by age, gender, Indigeneity, area of residence, and socioeconomic status. The risk of overweight levels and overweight + obesity rates were calculated according to World Health Organization guidelines. We identified that infants < 12 months currently have a higher prevalence of overweight + obesity (10.3%) and that those aged 12 to 23 months are generally at a higher risk of overweight (26.1%). The most relevant findings of this study, linking weight trends to sex, region, socioeconomic status, and indigeneity, show that overweight and obesity prevalences vary across the Mexican population, without presenting a specific behavior. There is a high prevalence of overweight and obesity among Mexican infants and a slight trend toward increased obesity in infants < 12 months. Weight monitoring and obesity prevention interventions focused on the first 1,000 days of life are essential.

https://doi.org/10.1590/0102-311xen046123

Infestation of rabbits with just-molted adults of the cattle tick Rhipicephalus microplus: biological parameters and efficiency
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Vargas-Hernandez, Milagros

; Montero-Espinosa, Carlos

; Sánchez-Villaurrutia, Dunia

; Duarte, Carlos Antonio

; Bechara, Gervasio Henrique

; Fuentes-Castillo, Alier

; Ancisar, Julio

; Suárez-Alba, José

; Mosqueda-Lobaina, Omar

; Suárez-Pedroso, Marisela

Revista Brasileira de Parasitologia Veterinária

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2023, Volume 32 Nº 1 elocation e016122

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract In this study, we report for the first time the successful infestation of rabbits with just-molted, unfed adults of Rhipicephalus microplus. Six New Zealand White rabbits were experimentally infested with 20 female and 20 male unfed adult ticks released into plastic chambers fixed on the shaved backs of each host. The attachment and feeding processes were successful. The biological characteristics of the ticks and the occurrence of adverse events in the tick-attachment area were studied. The average engorgement period was 10.7 days, and 33.3% of the engorged females completed the parasitic phase. The average weight of the recovered engorged females was 149.8 mg, with an average egg mass weight of 70.9 mg, a conversion efficiency index of 47.3%, and a hatching percentage of 88.31%. The adverse reactions found in the tick-attachment area were the usual inflammatory responses of the organism to infestation by these ectoparasites; however, it did not prevent the ticks from feeding and completing their life cycle. These data indicate that the infestation of rabbits with just-molted, unfed adult ticks could be a valuable, alternative animal model for rapid and economical evaluation of vaccine candidates and new molecules with acaricidal activity against Rhipicephalus microplus.

Resumo Neste estudo, relata-se, pela primeira vez, o sucesso da infestação de coelhos por carrapatos adultos recém-mudados e não alimentados. Seis coelhos brancos da Nova Zelândia foram infestados artificialmente com 20 carrapatos adultos fêmeas e 20 machos adultos não alimentados no interior de câmaras de plástico fixadas no dorso de cada hospedeiro. Os processos de fixação e alimentação dos carrapatos foram bem sucedidos. Foram estudadas as características biológicas dos carrapatos e a ocorrência de eventos adversos na área de fixação do ectoparasito. O período médio de ingurgitamento foi de 10,7 dias, e 33,3% das fêmeas ingurgitadas completaram a fase parasitária. O peso médio das fêmeas ingurgitadas recuperadas foi de 149,8 mg, com peso médio da massa de ovos de 70,9 mg, índice de produção de ovos de 47,3% e porcentagem de incubação de 88,31%. Uma resposta inflamatória usual do organismo à infestação por esses ectoparasitas foi a única reação adversa encontrada na área de fixação dos carrapatos, o que não impediu que eles se alimentassem e completassem seu ciclo de vida. Esses dados apontam que a infestação de coelhos com carrapatos adultos recém-mudados e não alimentados pode ser um modelo animal alternativo e útil para a avaliação rápida e econômica de candidatos a vacinas e novas moléculas com atividade acaricida contra Rhipicephalus microplus.

https://doi.org/10.1590/s1984-29612023006

Trends in overweight and obesity in children under 24 months of age in Mexico (2012-2020): analysis of four national health surveys
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Cárdenas-Villarreal, Velia Margarita

; Hernandez-Barrera, Lucia

; Castro-Sifuentes, Danilo

; Guevara-Valtier, Milton Carlos

; Trejo-Valdivia, Belem

Cadernos de Saúde Pública

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2023, Volume 39 Nº 12 elocation e00046123

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/0102-311xen046123

Fibrilación auricular en población mexicana: Diferencias en presentación, comorbilidades y factores de riesgo entre hombres y mujeres
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Rodríguez-Reyes, Humberto

; Laguna-Muñoz, César I.

; Gallegos-de Luna, Carlos F.

; Ríos-Ibarra, Manuel O. de los

; Salas-Pacheco, José L.

; Leyva-Pons, José L.

; Muñoz-Gutiérrez, Luz M.

; Vargas-Hernandez, Arturo

; Rodríguez-Muñoz, Karla M.

; Barragán-Luna, Jaime

; Alcocer-Gamba, Marco A.

; Cortez-Lawrenz, Jorge

; Farjat-Ruiz, Julio

Archivos de cardiología de México

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Set 2022, Volume 92 Nº 3 Páginas 349 - 357

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Objective: To know the epidemiological behavior and associations of AF in Mexican population. Material and methods: 8,686 patients from 38 cardiologists participating in REMECAR were analyzed. They were divided by gender and age, the comorbidities studied were obesity, chronic kidney disease (CKD), high blood pressure (HBP), diabetes mellitus (DM), dyslipidemia, stroke, chronic obstructive pulmonary disease (COPD), hypothyroidism, heart failure (HF) and ischemic heart disease (IHD). Program used: IBM SPSS Statistic. Results: AF was diagnosed in 498 patients (5.7%), with higher prevalence in men (6.1% vs. 5.3%) and older age in women (74.3 ± 12.1 vs. 70.5 + -12.3 years, p<0.0001). In those under 60 years, AF was associated in women with HF, in men with CKD, DM, stroke, hypothyroidism and HF. In women older than 60 years, AF was associated with CKD, dyslipidemia, stroke, chronic COPD and HF, in men with CKD, stroke, COPD, hypothyroidism, HF and IHD. AF in women increase the probability 1.13 for obesity, 1.13 for HBP, 2.8 for CKD, 2.9 for COPD, 4.3 for stroke and 6.5 for HF, in men increase the probability 1.05 for HBP, 1.4 for DM, 2.1 for CKD, 2.4 for COPD, 3.0 for hypothyroidism, 4.7 for stroke and 6.0 for HF. Conclusions: AF is a very common arrhythmia, with a higher prevalence in patients attending the cardiology consultation, in men and with an older age of presentation in women. The older the age, the higher the prevalence of AF and comorbidities, HF is the most frequent condition associated with AF.

Resumen Objetivo: Conocer el comportamiento epidemiológico y asociaciones de la FA en población mexicana. Material y métodos: Analizamos 8,686 pacientes de 38 cardiólogos inscritos en REMECAR, divididos por edad y sexo. Comorbilidades estudiadas: obesidad, ERC, HTA, DM, dislipidemia, EVC, EPOC, hipotiroidismo, IC y CI. Programa: IBM SPSS. Resultados: FA en 498 pacientes (5.7%), mayor prevalencia en hombres (6.1 vs. 5.3%), mayor edad en mujeres (74.3 ± 12.1 vs. 70.5 ± 12.3 años, p < 0.0001). En mujeres menores de 60 años la FA se asoció con IC (p = 0.041), en hombres con ERC (p = 0.43), DM (p = 0.009), EVC (p = 0.001), hipotiroidismo (p = 0.001) e IC (p = 0.001). En mujeres mayores de 60 años se asoció con ERC (p = 0.001), dislipidemia (p = 0.001), EVC (p = 0.001), EPOC (p = 0.001) e IC (p = 0.001), en hombres con ERC (p = 0.002), EVC (p = 0.001), EPOC (p = 0.002), hipotiroidismo (p = 0.002), IC (p = 0.001) y CI (p = 0.033). En mujeres la FA se asoció con 1.13 veces mayor probabilidad de obesidad, 1.13 de HTA, 2.8 de ERC, 2.9 de EPOC, 4.3 de EVC y 6.5 de IC, en hombres la FA se asoció con 1.05 veces mas probabilidad de HTA, 1.4 de DM, 2.1 de ERC, 2.4 de EPOC, 3 de hipotiroidismo, 4.7 de EVC y 6 de IC. Conclusiones: La FA es una arritmia muy frecuente, con mayor prevalencia en pacientes que acuden a consulta de cardiología, en hombres y mayor edad de presentación en las mujeres. A mayor edad, mayor prevalencia de FA y de comorbilidades, la IC es la condición más frecuente con la que se asoció la FA.

https://doi.org/10.24875/acm.21000120 138 downloads

Secure Exchange of Medical Images Via Extended Visual Cryptography
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Olvera-Martinez, Luis Angel

; Cedillo-Hernandez, Manuel

; Diaz-Rodriguez, Carlos Adolfo

; Jimenez-Borgonio, Enrique Tonatiuh

Revista mexicana de ingeniería biomédica

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Ago 2022, Volume 43 Nº 2 elocation 1275

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

RESUMEN La seguridad de imágenes médicas está incrementando su importancia para preservar la integridad y la confidencialidad de la información (datos médicos), frente a usuarios malintencionados dada su importancia en el diagnóstico oportuno y acertado. En este contexto, se han desarrollado varias técnicas para proteger las imágenes médicas, como el cifrado, la ocultación de datos, el etiquetado de imágenes, la aplicación de algoritmos Hash, etc. Este trabajo propone una técnica para cifrar imágenes médicas añadiendo los metadatos dentro de una imagen de cubierta, basada en la criptografía visual extendida, así como la inclusión de una función tipo Hash para comprobar la integridad de la imagen y los metadatos una vez estos sean recuperados. El método propuesto en este trabajo se implementa utilizando imágenes médicas con una resolución en escala de grises de [0,4095] es decir una profundidad de 12 bits/ píxel e imágenes en color con 24 bits/píxel de profundidad. Los resultados experimentales demuestran la eficacia del método propuesto en la tarea de transmisión segura de imágenes médicas permitiendo una mayor capacidad de ocultamiento, una menor distorsión en la calidad visual de la imagen con los datos médicos ocultos, así como un medio para comprobar la integridad de los datos enviados, en comparación con los artículos publicados.

ABSTRACT Medical image security is acquiring its importance to preserve the integrity and confidentiality of information (medical data) from malicious users given its importance in timely and successful diagnosis. In this context, several techniques have been developed to protect medical images, such as encryption, data hiding, image tagging, application of Hash algorithms, etc. This paper proposes a technique to cipher medical images by adding the metadata inside a cover image, based on extended visual cryptography as well as the inclusion of a Hash-like function to verify the integrity of the image and the metadata once they are recovered. The method proposed in this work is implemented using medical images with a grayscale resolution of [0,4095] that is a depth of 12 bits/pixel and color images with 24 bits/pixel depth. Experimental results prove the effectiveness of the proposed method in the task of secure exchange of medical images by allowing higher hiding capability, lower distortion in the visual quality of the image with the hidden medical data, as well as a means to verify the integrity of the sent data, compared to state-of-the-art.

https://doi.org/10.17488/rmib.43.2.5 1 downloads

Differences between COVID-19-induced acute kidney injury and chronic kidney disease patients
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Aroca-Martínez, Gustavo

; Musso, Carlos G.

; Avendaño-Echavez, Lil

; Vélez-Verbel, María

; Chartouni-Narvaez, Stefani

; Hernandez, Sandra

; Hinojosa-Vidal, Mauricio Andres

; Espitaleta, Zilac

; Cadena-Bonfanti, Andrés

Brazilian Journal of Nephrology

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Jun 2022, Volume 44 Nº 2 Páginas 155 - 163

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Este artigo descreve as principais diferenças entre a lesão renal aguda induzida por COVID-19 (LRA-COVID19) em pacientes com função renal normal prévia (LRA-FRN) e aqueles com doença renal crônica (LRA-DRC) atendidos em uma clínica de alta complexidade em Barranquilla (Colômbia). Material e Métodos: Os pacientes incluídos neste estudo (n: 572) foram aqueles com um diagnóstico positivo de COVID-19 confirmado pela detecção de PCR positivo para SARS-CoV-2. Destes pacientes, 188 desenvolveram LRA durante sua internação. Foram registrados os dados epidemiológicos, os parâmetros séricos e o estado de fragilidade clínica dos pacientes. Foram feitas a análise estatística e a comparação entre pacientes com LRA-FRN, LRA-DRC, e pacientes sem LRA. Resultados: A incidência de LRA induzida por COVID-19 foi de 33%, com a maioria classificada como AKIN 1, 16% exigindo terapia renal substitutiva, e a mortalidade por LRA-COVID19 foi de 68%. Foi registrada uma prevalência significativamente mais alta de hipertensão, doença cardíaca e proteína C reativa sérica e valores mais baixos de albumina em pacientes com LRA-DRC. A taxa de mortalidade, a necessidade de ventilação invasiva e os níveis de dímero-D foram significativamente mais altos em pacientes com LRA-FRN. Conclusão: Foram documentados padrões clínicos diferentes entre LRA-FRN e LRA-DRC.

Abstract Introduction: This article describes the main differences between COVID-19-induced acute kidney injury (AKI-COVID19) in patients with previous normal renal function (AKI-NRF) and those with chronic kidney disease (AKI-CKD) treated in a high complexity clinic in Barranquilla (Colombia). Material and Methods: The patients included in this study (n: 572) were those with a positive diagnosis of COVID-19 confirmed by detection of a positive PCR for SARS-CoV-2. Of these patients, 188 developed AKI during their hospital stay. Patients’ epidemiological data, serum parameters, and clinical frailty status were recorded. Statistical analysis and comparison among AKI-NRF, AKI-CKD, and non-AKI patients were performed. Results: The incidence of COVID-19-induced AKI was 33%, with the majority classified as AKIN 1, 16% requiring renal replacement therapy, and AKI-COVID19 mortality of 68%. A significantly higher prevalence of hypertension, cardiac disease, and serum reactive C-protein and lower albumin values in AKI-CKD patients was recorded. Mortality rate, invasive ventilation requirement, and D-dimer levels were significantly higher in AKI-NRF patients: Conclusion: Different clinical patterns between AKI-NRF and AKI-CKD were documented.

https://doi.org/10.1590/2175-8239-jbn-2021-0161

Selective Pb(II)-Imprinted Polymer for Solid Phase Extraction in the Trace Determination of Lead in Infant Formula by Capillary Electrophoresis
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Flores-Aguilar, Juan Francisco

; Islas, Gabriela

; Rodríguez, José Antonio

; Paez-Hernandez, María Elena

; Galán-Vidal, Carlos Andrés

; Ibarra, Israel Samuel

Journal of the Mexican Chemical Society

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Jun 2022, Volume 66 Nº 2 Páginas 221 - 236

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract A lead ion-imprinted polymer (IIP) based on methacrylic acid (MAA) and 4-vinylpyridine (4VP) as functional monomers has been synthesized by a radical precipitation method. The complex Pb-MAA-4VP was polymerized with ethylene glycol dimethacrylate as the cross-linker agent. The material was used in solid phase extraction (SPE) coupled with capillary electrophoresis (CE) for the determination of lead in infant formula samples. The physical-chemical properties of the IIP were characterized by scanning electron microscopy, IR spectroscopy, and Freundlich and Dubinin-Raduskevich models. The IIP selectivity was determined in presence of Ca(II), Mg(II), Cd(II), Cr(III) and Cu(II), which are present in the infant formula sample. The proposed methodology (SPE-CE) for the determination of lead has a limit of detection of 0.5 µg L-1 and a limit of quantification of 1.5 µg L-1, with an intra and inter-day repeatability of less than 5 % RSD in all cases. Four of twenty samples were positive for lead with concentrations ranging from 10 to 43 µg kg-1, and the results were compared with ETAAS. ANOVA demonstrated no significant difference between the results obtained by SPE-CE and ETAAS (α = 0.05 %).

Resumen Se realizó la síntesis de un polímero impreso de iones (IIP) vía radicales libres para la extracción efectiva de plomo, empleando como monómeros funcionales ácido metacrilico (MAA) y 4-vinilpiridina (4VP). El complejo Pb-MAA-4VP fue polimerizado empleando al dimetacrilato de etilenglicol como agente entrecruzante. El polímero fue utilizado en un sistema de extracción en fase sólida (SPE) acoplado a electroforesis capilar (CE) en la determinación de plomo en muestras de fórmulas infantiles. El IIP óptimo fue caracterizado respecto a su morfología y propiedades fisicoquímicas mediante microscopia electrónica de barrido, espectroscopia IR e isotermas de adsorción (modelo Freundlich y Dubinin-Raduskevich). La selectividad del IIP se estudió en presencia de iones metálicos contenidos en las fórmulas infantiles tales como: Ca(II), Mg(II), Cd(II), Cr(III) y Cu(II). La metodología propuesta en el presente trabajo (IIP-SPE-CE) mostró límites de detección de 0.5 µg L-1 y límites de cuantificación de 1.5 µg L-1, con una repetitividad y reproducibilidad adecuadas (< 5 % DER) en todos los casos. Cuatro de las veinte muestras analizadas dieron positivo a la presencia de plomo con concentraciones entre 10 a 43 µg L-1, dichos resultados fueron comparados con una metodología de referencia (ETAAS). El análisis de ANOVA demostró que no existe diferencia significativa entre los resultados obtenidos por IIP-SPE-CE y ETAAS (α=0.05 %).

https://doi.org/10.29356/jmcs.v66i2.1694

10.

Short-tailed pipefish (Microphis brachyurus) juvenile culture: effect of stocking density on growth, survival and condition factor
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Martinez-Cardenas, Leonardo

; Hernandez-Cortez, Miriam I.

; Castañeda-Chavez, María R.

; Lango-Reynoso, Fabiola

; Valdez-Hernandez, Edna F.

; Ponce-Palafox, Jesús T.

; Espinosa-Chaurand, Daniel

; Álvarez-González, Carlos A.

Latin american journal of aquatic research

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Mai 2022, Volume 50 Nº 2 Páginas 227 - 235

Resumo: En | Texto: En | PDF: En

ABSTRACT The present study aimed to test the effect of three stocking densities: 100, 200, and 300 ind m-3 (D100, D200, and D300, respectively) on survival, growth (weight and total length), and condition factor of Microphis brachyurus. At the end of the six-week trial, there were no significant differences in the fish's survival, growth, and condition. The results suggest that this species presents high adaptability under culture conditions. A suboptimal stocking density generates a suboptimal use of infrastructure and decreases the production system's profitability. Based on the present study, a stocking density of 300 ind m-3 is recommended to increase the aquaculture infrastructure's profitability for ornamental or conservation purposes.

https://doi.org/10.3856/vol50-issue2-fulltext-2786 22 downloads

11.

Atención al niño con bronquiolitis: consideraciones clínico-terapéuticas generales
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Yanes Macías, Juan Carlos

; Fonseca Hernandez, Mercedes

; García Rodríguez, Ileana

; Llul Tombo, Caridad

; Tio González, Daimy

; Díaz Ceballos, Juan Camilo

MediSur

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Abr 2022, Volume 20 Nº 2 Páginas 175 - 182

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT Acute bronchiolitis represents a significant demand for care, not only in primary care, but also at the hospital level, with high assistance requirements in the emergency area and a significant number of admissions in epidemic times, which causes great economic costs . General considerations, drawn up by consensus, are presented that highlight the clinical-therapeutic aspects of the disease and will facilitate the management of this condition at the primary and hospital level.

RESUMEN La bronquiolitis aguda supone una importante demanda asistencial, no sólo en el ámbito de la atención primaria, sino también a nivel hospitalario, con grandes requerimientos de asistencia en el área de urgencias e importante número de ingresos en época epidémica, lo que ocasiona grandes costos económicos. Se presentan consideraciones generales, elaboradas por consenso, que resaltan los aspectos clínico-terapéuticos de la enfermedad y facilitarán el manejo de esta afección a nivel primario y hospitalario.

12.

Low molecular weight heparin is useful in adult COVID-19 inpatients. Experience during the first Spanish wave: observational study
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Gonzalez-Porras, Jose Ramon

; Belhassen-Garcia, Moncef

; Lopez-Bernus, Amparo

; Vaquero-Roncero, Luis Mario

; Rodriguez, Beatriz

; Carbonell, Cristina

; Azibeiro, Raul

; Hernandez-Sanchez, Alberto

; Martin-Gonzalez, Jose Ignacio

; Manrique, Juan Miguel

; Alonso-Claudio, Gloria

; Alvarez-Navia, Felipe

; Madruga-Martin, Jose Ignacio

; Macias-Casanova, Ronald Paul

; García-Criado, Jorge

; Lozano, Francisco

; Moyano, Jose Carlos

; Sanchez-Hernandez, Miguel Vicente

; Sagredo-Meneses, Víctor

; Borras, Rafael

; Bastida, Jose María

; Hernández-Pérez, Guillermo

; Chamorro, Antonio Javier

; Marcos, Miguel

; Martin-Oterino, Jose Angel

Sao Paulo Medical Journal

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Fev 2022, Volume 140 Nº 1 Páginas 123 - 133

Resumo: En | Texto: En | PDF: En

ABSTRACT BACKGROUND: The intensity of the thromboprophylaxis needed as a potential factor for preventing inpatient mortality due to coronavirus disease-19 (COVID-19) remains unclear. OBJECTIVE: To explore the association between anticoagulation intensity and COVID-19 survival. DESIGN AND SETTING: Retrospective observational study in a tertiary-level hospital in Spain. METHODS: Low-molecular-weight heparin (LMWH) status was ascertained based on prescription at admission. To control for immortal time bias, anticoagulant use was analyzed as a time-dependent variable. RESULTS: 690 patients were included (median age, 72 years). LMWH was administered to 615 patients, starting from hospital admission (89.1%). 410 (66.7%) received prophylactic-dose LMWH; 120 (19.5%), therapeutic-dose LMWH; and another 85 (13.8%) who presented respiratory failure, high D-dimer levels (> 3 mg/l) and non-worsening of inflammation markers received prophylaxis of intermediate-dose LMWH. The overall inpatient-mortality rate was 38.5%. The anticoagulant nonuser group presented higher mortality risk than each of the following groups: any LMWH users (HR 2.1; 95% CI: 1.40-3.15); the prophylactic-dose heparin group (HR 2.39; 95% CI, 1.57-3.64); and the users of heparin dose according to biomarkers (HR 6.52; 95% CI, 2.95-14.41). 3.4% of the patients experienced major hemorrhage. 2.8% of the patients developed an episode of thromboembolism. CONCLUSIONS: This observational study showed that LMWH administered at the time of admission was associated with lower mortality among unselected adult COVID-19 inpatients. The magnitude of the benefit may have been greatest for the intermediate-dose subgroup. Randomized controlled trials to assess the benefit of heparin within different therapeutic regimes for COVID-19 patients are required.

https://doi.org/10.1590/1516-3180.2021.0098.r1.08062021

13.

Phylogenetic analysis of avian influenza viruses from migratory waterfowl at Pacific wetlands
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Iša, Pavel

; Paulin, Luis Felipe

; Hernandez, Jesus

; Montalvo-Corral, Maricela

; López, Susana

; Arias, Carlos F

Veterinaria México OA

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2022, Volume 9 elocation e702

Resumo: En | Texto: En | PDF: En

Abstract The surveillance of influenza A viruses (IAV) in migratory waterfowl is of great importance, given the possibility of transmission to susceptible hosts and introduction of viral subtypes, including highly pathogenic strains, to new geographic regions. IAV were previously identified from migratory birds in two wetlands located in Mexico during two wintering seasons. Using next-generation sequencing, thirteen samples of RNA from the field sampled cloacal swabs were subjected to whole genome sequencing. Seven whole IAV genomes were obtained, while remaining six samples provided partial results. Eight different hemagglutinin (HA) and neuraminidase (NA) combinations were identified in analyzed samples, while the analysis of the remaining genes in seven whole genome samples demonstrated four different combinations of viral segments, suggesting a diversity of circulating IAV. Phylogenetic analysis of samples whose whole genomes were sequenced showed that they are closely related to North American IAV, with some segments (NP, H6 and H11) related to the Eurasian virus. The use of high-throughput technologies enabled genetic characterization of field samples and contributed to fostering our knowledge of IAV genomics and virus circulation in Mexico, a lowly surveyed but biological and epidemiological relevant region, thus highlighting the need for future studies in Mexican wetlands.

https://doi.org/10.22201/fmvz.24486760e.2022.702

14.

Cross-cultural validity of the five items Mindful Attention Awareness Scale (MAAS-5) in Peru and Mexico during the COVID-19 pandemic
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Reyes-Bossio, Mario

; Zapparigli, Emilio Lafferrnaderie

; Caycho-Rodríguez, Tomás

; Carbajal-León, Carlos

; Castaman, Luis Alberto Olavarria

; Pino, Giovana Lourdes Hernandez

; Sanchez, Raymundo Calderon

; Barbosa-Granados, Sergio

Psicologia: Reflexão e Crítica

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2022, Volume 35 elocation 12

Resumo: En | Texto: En | PDF: En

Abstract The Spanish version of the 5-item Mindful Attention Awareness Scale (MAAS-5) is a brief measure of the general tendency to be attentive and aware of experiences in the present moment during daily life. The MAAS-5 has been used in different countries; however, an assessment of its cross-cultural measurement invariance (MI) has not been conducted. Therefore, the study aimed to evaluate the cross-cultural measurement invariance of the MAAS-5 in university students from two countries: Peru and Mexico. A total of 1144 university students from Peru (N = 822) and Mexico (N = 322) responded online to the Spanish version of the 5-item Mindful Attention Awareness Scale (MAAS-5). A multigroup confirmatory factor analysis was performed. Measurement invariance tests the hypothesis that the model behind a set of scores is comparable between groups. The results showed that the unidimensional structure of the MAAS-5 is the same between Peruvian and Mexican university students. Therefore, it is suggested that university students from both countries conceptualize the mindfulness in a similar way. As a result, the MAAS-5 can be used to compare differences between countries. No significant differences were observed in the MAAS-5 score between Peruvian and Mexican university students. The present study contributes to a better understanding of the psychometric properties of the MAAS-5 by presenting MI results in two Latin American countries. Implications of the findings are discussed, which will facilitate a more solid and reliable use of the MAAS-5 in future cross-cultural studies.

https://doi.org/10.1186/s41155-022-00218-y

15.

Differences between COVID-19-induced acute kidney injury and chronic kidney disease patients
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Aroca-Martínez, Gustavo

; Musso, Carlos G.

; Avendaño-Echavez, Lil

; Vélez-Verbel, María

; Chartouni-Narvaez, Stefani

; Hernandez, Sandra

; Hinojosa-Vidal, Mauricio Andres

; Espitaleta, Zilac

; Cadena-Bonfanti, Andrés

Brazilian Journal of Nephrology

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2022, Nº ahead

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/2175-8239-jbn-2021-0161

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