Resumo Objetivos: descrever o perfil de mulheres acometidas por parto prematuro e os desfechos neonatais em maternidade de referência, na cidade de Fortaleza-CE, Brasil. Métodos: estudo do tipo documental, descritivo, retrospectivo, com abordagem quantitativa, realizadode janeiro a dezembro de 2017, com 253 prontuários de mulheres que tiveram parto prematuro em maternidade de referência. Resultados: média de idade de 28 anos, com prevalência de mulheres vivendo em união estável, ensino médio completo, sem trabalho formal. A média gestacional foi de três gravidezes, idade gestacional de 34 semanas e trêsdias e seis consultas de pré-natal, iniciando no primeiro trimestre. A maior intercorrência foi a pré-eclâmpsia. Relacionado aos dados neonatais, houve prevalência de recém-nascidos do sexo masculino, com média de 2,251 quilos e escore sete no Apgar do 1º minuto e oito, no Apgar do 5º minuto. Recémnascidos indo para alojamento conjunto após o parto e em ar ambiente, tendo passado, em média, 12,71 dias internados. Conclusões: no caso da pesquisa, conhecer o perfil dessa mulher e os desfechos do recém-nascido prematuro é útil para estimular as políticas públicas e diminuir as sequelas para mãe e bebê.

Abstract Objectives: to describe the profile of women affected with premature childbirth and neonatal outcomes at a referral maternity in the city of Fortaleza-CE, Brazil. Methods: descriptive and retrospective documentary type study, with a quantitative approach, carried out from January to December, 2017, with 253 medical records of women who had premature childbirth in a referral maternity. Results: the average age was 28, with the prevalence of women living in a stable union, graduated from high school and without formal work. The gestational mean average was three pregnancies, gestational age of 34 weeks and three days, and six prenatal consultations, starting in the first trimester. The major intercurrence was pre-eclampsia. In relation to the neonatal data, there was a prevalence of male newborns, with an average of 2.251 kg and a score of seven on the 1-minute Apgar and eight on the 5-minute Apgar. Newborns in going to a hospital accommodation after childbirth and in room air, spending an average of 12.71 days in the hospital. Conclusion: in this case of this research, knowing the woman’s profile and the outcomes in premature newborns is useful to encourage public policies and reduce the sequelae on mother and baby

AbstractThe topological derivative measures the sensitivity of a shape functional with respect to an infinitesimal singular domain perturbation, such as the insertion of holes, inclusions or source-terms. The topological derivative has been successfully applied in obtaining the optimal topology for a large class of physics and engineering problems. In this paper the topological derivative is applied in the context of topology optimization of structures subject to multiple load-cases. In particular, the structural compliance under plane stress or plane strain assumptions is minimized under volume constraint. For the sake of completeness, the topological asymptotic analysis of the total potential energy with respect to the nucleation of a small circular inclusion is developed in all details. Since we are dealing with multiple load-cases, a multi-objective optimization problem is proposed and the topological sensitivity is obtained as a sum of the topological derivatives associated with each load-case. The volume constraint is imposed through the Augmented Lagrangian Method. The obtained result is used to devise a topology optimization algorithm based on the topological derivative together with a level-set domain representation method. Finally, several finite element-based examples of structural optimization are presented.