ABSTRACT Introduction: Pulse wave velocity is used to diagnose central arterial stiffness (CAS) and quantify healthy vascular aging (HVA). Objective: To evaluate the CAS and HVA in elderly patients with systemic blood pressure levels classified as optimal/normal. Methods: A total of 102 patients without comorbidities and with systolic pressure (SP) < 120 mmHg and diastolic pressure (DP) < 80 mmHg were selected from the EVOPIU database (Pulse Wave Velocity of Elderly Individuals in an Urban area of Brazil). The carotid-femoral pulse wave velocity (c-fPWV) and the central and peripheral pressures were evaluated in all patients. The patients were divided into four groups: G1: (n = 19, with c-fPWV < 7.6 m/s, without medication), G2 (n = 26, c-fPWV ≥ 7.6 m/s; without medication), G3 (n = 25, c-fPWV < 7.6 m/s with antihypertensive medication), and G4 (n = 32, c-fPWV ≥ 7.6 m/s with antihypertensive medication). Results: In our sample, 56.7% of patients had c-fPWV ≥ 7.6 m/s. The central systolic pressure in G1 [99 (10) mmHg] was lower than that found in the other three groups [vs. 112 (14) mmHg, 111 (15), 112 (20) mmHg; P < 0.05)]. Conclusion: Older people with optimal arterial blood pressure do not necessarily have HVA and could have c-fPWV values close to the limits established for CAS diagnosis.

RESUMO Introdução: A velocidade da onda de pulso é usada para diagnosticar a rigidez arterial central (RAC) e quantificar o envelhecimento vascular saudável (EVS). Objetivo: Avaliar a RAC e o EVS em pacientes idosos com níveis pressóricos sistêmicos classificados como ideais/normais. Métodos: Um total de 102 pacientes sem comorbidades e com pressão sistólica (PS) < 120 mmHg e pressão diastólica (PD) < 80 mmHg foram selecionados do banco de dados EVOPIU (Estudo da Velocidade de Onda de Pulso em Idosos em área Urbana no Brasil). Foram avaliadas a velocidade da onda de pulso carotídeo-femoral (VOPcf) e as pressões central e periférica em todos os pacientes. Os pacientes foram divididos em quatro grupos: G1: (n = 19; com VOPcf < 7,6 m/s; sem medicação), G2 (n = 26; VOPcf ≥ 7,6 m/s; sem medicação), G3 (n = 25; VOPcf < 7,6 m/s com medicação anti-hipertensiva), e G4 (n = 32; VOPcf ≥ 7,6 m/s com medicação anti-hipertensiva). Resultados: Em nossa amostra, 56,7% dos pacientes apresentaram VOPcf ≥ 7,6 m/s. A pressão sistólica central no G1 [99 (10) mmHg] foi inferior à encontrada nos outros três grupos [vs. 112 (14) mmHg, 111 (15), 112 (20) mmHg; P < 0,05)]. Conclusão: Pessoas idosas com pressão arterial ideal não necessariamente têm EVS e podem apresentar valores de VOPcf próximos aos limites estabelecidos para o diagnóstico de RAC.

ABSTRACT This work aimed to evaluate the effect of sources and doses of nitrogen on the initial growth and quality of Melaleuca alternifolia Cheel (melaleuca) seedlings. The nitrogen sources were: ammonium nitrate, calcium nitrate and ammonium sulfate, established in five doses (0, 50, 100, 150 and 200 mg dm-3 of N) equally parceled out and applied on the 25th, 50th, 75th and 100 days after transplanting. The experiment was arranged in complete randomized blocks, in (3 x 5) factorial design, in red yellow latosol, with four repetitions. After 125 days of transplanting data regarding height, collar diameter, aerial part dry weight and root, and the ratios between height and collar diameter, height aerial part and dry weight, aerial part dry weight and root dry weight and Dickson quality index (IQD) were collected. There were no significant effects from the nitrogen sources, however the doses of N were positive and significant for all traits except for the ratio between height and collar diameter. The best standards of seedlings quality were obtained from the application of 100 mg.dm-3 of N.

RESUMO O trabalho teve como objetivo avaliar o efeito de fontes e doses de N no crescimento e qualidade de mudas de Melaleuca alternifolia Cheel (melaleuca). As fontes de N utilizadas foram nitrato de amônio, nitrato de cálcio e sulfato de amônio em cinco doses (0, 50, 100, 150 e 200 mg dm-3 de N) igualmente parceladas e aplicadas aos 25, 50, 75 e 100 dias após a repicagem. O delineamento estatístico adotado foi o em blocos casualizados, em esquema fatorial (3 x 5), em Latossolo Vermelho-Amarelo, com quatro repetições. Aos 125 dias após a repicagem, foram colhidos dados de altura, diâmetro, massa seca da parte aérea, massa seca de raízes e massa seca total, além das relações altura/diâmetro, massa seca da parte aérea/massa seca de raízes, altura/massa seca da parte aérea e índice de qualidade de Dickson. A aplicação de fertilizantes nitrogenados resultou em ganhos significativos no crescimento e qualidade das mudas. Não houve efeito significativo das fontes, no entanto as doses de N tiveram efeito positivo e significativo para todas as características exceto para a relação altura diâmetro do coleto. O melhor padrão de qualidade das mudas foi obtido com a aplicação de 100 mg.dm-3 de N.

RESUMO Introdução: A velocidade da onda de pulso é usada para diagnosticar a rigidez arterial central (RAC) e quantificar o envelhecimento vascular saudável (EVS). Objetivo: Avaliar a RAC e o EVS em pacientes idosos com níveis pressóricos sistêmicos classificados como ideais/normais. Métodos: Um total de 102 pacientes sem comorbidades e com pressão sistólica (PS) < 120 mmHg e pressão diastólica (PD) < 80 mmHg foram selecionados do banco de dados EVOPIU (Estudo da Velocidade de Onda de Pulso em Idosos em área Urbana no Brasil). Foram avaliadas a velocidade da onda de pulso carotídeo-femoral (VOPcf) e as pressões central e periférica em todos os pacientes. Os pacientes foram divididos em quatro grupos: G1: (n = 19; com VOPcf < 7,6 m/s; sem medicação), G2 (n = 26; VOPcf ≥ 7,6 m/s; sem medicação), G3 (n = 25; VOPcf < 7,6 m/s com medicação anti-hipertensiva), e G4 (n = 32; VOPcf ≥ 7,6 m/s com medicação anti-hipertensiva). Resultados: Em nossa amostra, 56,7% dos pacientes apresentaram VOPcf ≥ 7,6 m/s. A pressão sistólica central no G1 [99 (10) mmHg] foi inferior à encontrada nos outros três grupos [vs. 112 (14) mmHg, 111 (15), 112 (20) mmHg; P < 0,05)]. Conclusão: Pessoas idosas com pressão arterial ideal não necessariamente têm EVS e podem apresentar valores de VOPcf próximos aos limites estabelecidos para o diagnóstico de RAC.

ABSTRACT Introduction: Pulse wave velocity is used to diagnose central arterial stiffness (CAS) and quantify healthy vascular aging (HVA). Objective: To evaluate the CAS and HVA in elderly patients with systemic blood pressure levels classified as optimal/normal. Methods: A total of 102 patients without comorbidities and with systolic pressure (SP) < 120 mmHg and diastolic pressure (DP) < 80 mmHg were selected from the EVOPIU database (Pulse Wave Velocity of Elderly Individuals in an Urban area of Brazil). The carotid-femoral pulse wave velocity (c-fPWV) and the central and peripheral pressures were evaluated in all patients. The patients were divided into four groups: G1: (n = 19, with c-fPWV < 7.6 m/s, without medication), G2 (n = 26, c-fPWV ≥ 7.6 m/s; without medication), G3 (n = 25, c-fPWV < 7.6 m/s with antihypertensive medication), and G4 (n = 32, c-fPWV ≥ 7.6 m/s with antihypertensive medication). Results: In our sample, 56.7% of patients had c-fPWV ≥ 7.6 m/s. The central systolic pressure in G1 [99 (10) mmHg] was lower than that found in the other three groups [vs. 112 (14) mmHg, 111 (15), 112 (20) mmHg; P < 0.05)]. Conclusion: Older people with optimal arterial blood pressure do not necessarily have HVA and could have c-fPWV values close to the limits established for CAS diagnosis.

Abstract Objective: To identify and assess the current evidence available about the costs of managing hospitalized pediatric patients diagnosed with Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3) in upper-middle-income countries. Methods: The authors conducted a systematic review across seven key databases from database inception to July 2022. Costs extracted were converted into 2022 International Dollars using the Purchasing Power Parity-adjusted. PROSPERO identifier: CRD42020225757. Results: No eligible study for PIV3 was recovered. For RSV, cost analysis and COI studies were performed for populations in Colombia, China, Malaysia, and Mexico. Comparing the total economic impact, the lowest cost per patient at the pediatric ward was observed in Malaysia ($ 347.60), while the highest was in Colombia ($ 709.66). On the other hand, at pediatric ICU, the lowest cost was observed in China ($ 1068.26), while the highest was in Mexico ($ 3815.56). Although there is no consensus on the major cost driver, all included studies described that the medications (treatment) consumed over 30% of the total cost. A high rate of inappropriate prescription drugs was observed. Conclusion: The present study highlighted how RSV infection represents a substantial economic burden to health care systems and to society. The findings of the included studies suggest a possible association between baseline risk status and expenditures. Moreover, it was observed that an important amount of the cost is destinated to treatments that have no evidence or support in most clinical practice guidelines.

ABSTRACT. This study aimed to propose and compare metrics of accuracy and bias of genomic prediction of breeding values for traits with censored data. Genotypic and censored-phenotypic information were simulated for four traits with QTL heritability and polygenic heritability, respectively: C1: 0.07-0.07, C2: 0.07-0.00, C3: 0.27-0.27, and C4: 0.27-0.00. Genomic breeding values were predicted using the Mixed Cox and Truncated Normal models. The accuracy of the models was estimated based on the Pearson (PC), maximal (MC), and Pearson correlation for censored data (PCC) while the genomic bias was calculated via simple linear regression (SLR) and Tobit (TB). MC and PCC were statistically superior to PC for the trait C3 with 10 and 40% censored information, for 70% censorship, PCC yielded better results than MC and PC. For the other traits, the proposed measures were superior or statistically equal to the PC. The coefficients associated with the marginal effects (TB) presented estimates close to those obtained for the SLR method, while the coefficient related to the latent variable showed almost unchanged pattern with the increase in censorship in most cases. From a statistical point of view, the use of methodologies for censored data should be prioritized, even for low censoring percentages.

ABSTRACT Recently, the Capsicum chinense Jacquin pepper has been gaining prominence in the production of sauces, pastes and other food products. Due to the high demand for these peppers, it becomes even more necessary to obtain quality seeds to obtain greater productivity. Several factors can influence seed quality, so using logistic regression models to predict the percentage of seed germination can bring important results about the best production conditions. The present work aimed to compare logistic regression models using the ROC curve methodology to evaluate the germination capacity of Capsicum chinense Jacquin seeds. The factors evaluated were: variety (orange and red), fruit storage period (1, 7, and 14 days), extraction method (manual and mechanical), and seed storage period (3, 6, 9, and 12 months). By Akaike's information criterion (AIC) and the area under the ROC curve, the best model was the one with interaction between “cultivate”, “seed storage”, and “fruit storage”, without the “extraction method” factor. The model allowed to determine the chance of germination from the combination of these factors.

RESUMO Recentemente, a pimenta Capsicum chinense Jacquin tem adquirido destaque na produção de molhos, pastas e outros produtos alimentícios. Devido à alta procura desta pimenta, torna-se necessária a obtenção de sementes de qualidade a fim de se obter maior produtividade. Vários fatores podem influenciar na qualidade das sementes, de modo que a utilização de modelos de regressão logística para predizer a percentagem de germinação das sementes pode trazer resultados importantes acerca das melhores condições de produção. O presente trabalho objetivou comparar modelos de regressão logística utilizando a metodologia da curva Receiver Operating Characteristic (ROC) para avaliar a capacidade germinativa de sementes de Capsicum chinense Jacquin. Os fatores avaliados foram: cultivar (laranja e vermelho), período de armazenamento do fruto (1, 7 e 14 dias), método de extração (manual e mecânico) e período de armazenamento das sementes (3, 6, 9 e 12 meses). Pelo critério de informação de Akaike (AIC) e área abaixo da curva ROC, o melhor modelo foi aquele com interação entre “cultivar”, “armazenamento da semente” e “armazenamento do fruto”, sem o fator “método de extração”. O modelo permitiu determinar a chance de germinação a partir da combinação entre estes fatores.

RESUMO Platycodon grandiflorus é uma espécie ornamental que pode ser comercializada como flor de vaso; porém, apresenta ramos florais frágeis e pendentes. Reguladores de crescimento, como o paclobutrazol, são compostos que reduzem o alongamento do caule, permitindo a produção de plantas com formação mais compacta. Objetivou-se avaliar os efeitos de paclobutrazol no crescimento de platycodon, em casa-de-vegetação. O delineamento experimental foi em blocos inteiramente casualizados, em esquema fatorial 4 × 5, com quatro repetições. Os tratamentos consistiram de quatro variedades de platycodon ‘Astra Semi-Double’ (Blue, Lavender, Pink e White) e cinco doses de paclobutrazol (0; 1,25; 2,5; 3,75; e 5,0 mg vaso-1). A aplicação de paclobutrazol não afetou o diâmetro do caule, número de folhas, dias até a antese, número de flores ou botões florais e diâmetro da flor. O comprimento da parte aérea, área foliar e massa seca da parte aérea decresceram com o aumento da dose do regulador de crescimento. Lavender apresentou os maiores valores de comprimento da parte aérea, número de folhas, área foliar e massa seca da parte aérea. Pink teve a antese mais precoce, seguida de Blue e White, enquanto Lavender teve a antese mais tardia. A dose de 3,75 mg vaso-1 de paclobutrazol eficientemente controlou o crescimento e melhorou a qualidade visual de todas as variedades de platycodon.

ABSTRACT Platycodon grandiflorus is an ornamental species that can be marketed as a potted flower; however, it has fragile and bending floral stems. Plant growth regulators, such as paclobutrazol, are compounds that reduce stem elongation, enabling the production of plants with a more compact formation. This study aimed to evaluate the effects of paclobutrazol on platycodon growth, in a greenhouse. A completely randomized blocks experimental design was used in a 4 × 5 factorial scheme, with four replicates. The treatments consisted of four varieties of ‘Astra Semi-Double’ platycodon (Blue, Lavender, Pink and White) and five paclobutrazol doses (0, 1.25, 2.5, 3.75 and 5.0 mg pot-1). The paclobutrazol application did not affect the stem diameter, number of leaves, days until anthesis, number of flowers or flower buds, and flower diameter. The shoot length, leaf area and shoot dry mass decreased with higher doses of the growth regulator. Lavender showed the highest values for shoot length, number of leaves, leaf area and shoot dry mass. Pink had the earliest anthesis, followed by Blue and White, whereas Lavender had the latest anthesis. The dose of 3.75 mg pot-1 of paclobutrazol efficiently controlled the growth and improved the visual quality of all the platycodon varieties.

ABSTRACT BACKGROUND: The numbers of cases of arboviral diseases have increased in tropical and subtropical regions while the coronavirus disease (COVID-19) pandemic overwhelms healthcare systems worldwide. The clinical manifestations of arboviral diseases, especially dengue fever, can be very similar to COVID-19, and misdiagnoses are still a reality. In the meantime, outcomes for patients and healthcare systems in situations of possible syndemic have not yet been clarified. OBJECTIVE: We set out to conduct a systematic review to understand and summarize the evidence relating to clinical manifestations, disease severity and prognoses among patients coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and arboviruses. METHODS: We conducted a rapid systematic review with meta-analysis, on prospective and retrospective cohorts, case-control studies and case series of patients with confirmed diagnoses of SARS-CoV-2 and arboviral infection. We followed the Cochrane Handbook recommendations. We searched EMBASE, MEDLINE, Cochrane Library, LILACS, Scopus and Web of Science to identify published, ongoing and unpublished studies. We planned to extract data and assess the risk of bias and the certainty of evidence of the studies included, using the Quality in Prognosis Studies tool and the Grading of Recommendations Assessment. RESULTS: We were able to retrieve 2,407 citations using the search strategy, but none of the studies fulfilled the inclusion criteria. CONCLUSION: The clinical presentations, disease severity and prognoses of patients coinfected with SARS-CoV-2 and arboviruses remain unclear. Further prospective studies are necessary in order to provide useful information for clinical decision-making processes. Protocol registration number in the PROSPERO database: CRD42020183460

ABSTRACT BACKGROUND: Patients with immune-mediated inflammatory diseases (IMID) are at increased risk of infection. OBJECTIVE: To assess whether patients undergoing pharmacological treatment for IMID present higher risk of worse outcomes when diagnosed with COVID-19. DESIGN AND SETTING: Rapid systematic review conducted in the medical school of the Federal University of São Paulo (SP), Brazil. METHODS: We searched CENTRAL, MEDLINE, EMBASE, LILACS, SCOPUS, Web of Science, L·OVE, ClinicalTrials.gov and WHO-ICTRP for studies evaluating patients diagnosed with COVID-19 who were undergoing pharmacological treatment for IMID. Two authors selected studies, extracted data and assessed risk of bias and certainty of evidence, following the Cochrane recommendations. RESULTS: We identified 1,498 references, from which one cohort study was included. This compared patients with and without rheumatic diseases (RD) who all had been diagnosed with COVID-19. Those with RD seemed to have higher chances of hospitalization and mortality, but no statistical difference was detected between the groups: hospitalization: odds ratio (OR) 1.17; 95% confidence interval (CI) 0.6 to 2.29; mortality rate: OR 1.53; 95% CI 0.33 to 7.11 (very low certainty of evidence). Patients with RD were three times more likely to require admission to intensive care units (ICUs), with invasive mechanical ventilation (IMV), than those without RD: OR 3.72; 95% CI 1.35 to 10.26 (for both outcomes; very low certainty of evidence). CONCLUSION: Patients undergoing pharmacological treatment for IMID seem to present higher chances of requiring admission to ICUs, with IMV. Additional high-quality studies are needed to analyze the effects of different treatments for IMID.

Context and objective: While cases of COVID-19 disease increase daily worldwide, outbreaks of arboviral infections have affected health systems of countries in tropical regions. The outcomes for patients and health systems of a possible syndemic are not clarified yet. Thus, we aim to systematically review the literature searching for evidence that describes the clinical presentation, severity and prognostic of SARS-CoV-2 and Arboviral coinfection. Design and setting: Protocol for a rapid living systematic review, that will follow the Cochrane Handbook for Systematic Reviews recommendations. We will include prospective and retrospective cohort, case-control studies and case series of patients with confirmed diagnosis of SARS-CoV-2 and Arboviral infection. We will perform the search strategy with no language restrictions on Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS - LILACS, Scopus and WebOfScience to identify published, ongoing, and unpublished studies. The selection and extraction will be performed by two authors. We will perform the critical appraisal of included studies with the Newcastle-Ottawa Scale and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). &nbsp; &nbsp;

CONTEXT AND OBJECTIVE: The current health crisis due to COVID-19 is forcing us to profoundly rethink our social organizations and practices in health. While there is no effective treatment for the virus, staying home and social isolation are the control measures recommended by health authorities. The aim of this study is to perform a scoping review in order to summarize the current evidence in telehealth for COVID-19. METHODS: This study is a protocol to describe the rationale, hypothesis and planned methods of our scoping review. We will include randomized controlled trials (RCTs), observational cohort studies, case-control studies, cross-sectional studies, qualitative studies, and/or case series that describe telehealth interventions applied or developed to respond to COVID-19. We will search Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS - LILACS, and Scopus. We will include studies performed since December 2019 with no language restrictions. We will use the Risk of Bias tool and the Newcastle-Ottawa Scale to perform the critical appraisal of included studies. We will assess the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).

CONTEXT AND OBJECTIVE: Coronavirus disease 2019 (COVID-19) has emerged in China in December 2019 and rapidly spread. Although extraordinary efforts have been made on research regarding pharmacological interventions, none have proven effective. This is the protocol for a rapid living systematic review that aims to compare the effectiveness and safety of different pharmacological interventions for the treatment of COVID-19. METHODS: rapid living systematic review methodology with Network Meta-Analysis following the recommendations of Cochrane Handbook. We will include randomized controlled trials (RCT) and quasi-RCTs that evaluate single and/or combined pharmacological interventions at any dose for the treatment of COVID-19. We will search Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS - LILACS, Scopus and WebofScience to identify potentially eligible studies. No language restrictions will be used in the selection. We will perform the critical appraisal of included studies with the Risk of Bias tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).

CONTEXT AND OBJECTIVE: Determining prognostic factors in a context of health crises such as the COVID-19 scenario may provide the best possible care for patients and optimize the management and the resource utilization of the health system. Thus, we aim to systematically review the prognostic factors for different outcomes of patients with COVID-19. DESIGN AND SETTING: Protocol for a rapid living systematic review methodology following the recommendations proposed by the Cochrane Handbook. METHODS: We will include cohorts and case‐control studies. We will search Medline via PubMed, Embase via Elsevier, Cochrane Library - Cochrane Central Register of Controlled Trials (CENTRAL), Portal Regional BVS- LILACS, Scopus and WebofScience to identify studies. No language restrictions will be applied. We will perform the critical appraisal of included studies with the Quality in Prognosis Studies (QUIPS) tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).

CONTEXT AND OBJECTIVE: We propose to systematically review the available evidence to evaluate if patients with immune mediated or inflammatory diseases under pharmacological treatment with immunosuppressants, immunobiologics, DMARDs or targeted synthetic DMARDs have better or worse outcomes when infected by SARS-CoV-2. This study is a protocol for our rapid living systematic review. METHODS: Protocol for a rapid living systematic review methodology following the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) guidance. To conduct the rapid systematic review, we will employ abbreviated systematic review methods, including: not performing independent screens of abstracts and not searching grey literature. As this will be a living review, it will be continuously updated.

RESUMEN En los últimos años el uso de aguas salinas en la agricultura es una alternativa, principalmente en virtud de la escasez hídrica. Sin embargo, las plantas no toleran altos niveles de sales, por lo que el uso de atenuadores de estrés salino puede ser una estrategia para posibilitar el uso de aguas salinas en la agricultura. En este sentido, este trabajo tiene como objetivo evaluar el efecto de aguas salinas y aplicación de silicio sobre el crecimiento, pigmentos cloroplatísdicos, fluorescencia de la clorofila a y producción de remolacha. El experimento fue conducido en un diseño de bloques al azar, en factorial 5 X 5, referente a cinco niveles de conductividad eléctrica del agua de riego (CEa): (0,5; 1,3; 3,25; 5,2 y 6 dS m-1) y cinco dosis de silicio (0,00; 2,64; 9,08; 15,52 y 18,16 mL L-1), combinadas según la matriz experimental Compuesto Central de Box, con cuatro repeticiones y tres plantas por parcela. El aumento de la conductividad eléctrica en el agua de riego reduce el crecimiento y la producción de remolacha, pero los índices de clorofila, la producción de biomasa y la fluorescencia no están influenciados por el riego con aguas salinas. La aplicación de silicio a través del suelo promueve un incremento en el crecimiento y la fluorescencia de la clorofila a, sin embargo, no reduce el efecto nocivo del estrés salino. La conductividad eléctrica en el agua de riego por encima de 0,50 dS m-1 es suficiente para afectar negativamente el cultivo de la remolacha y la dosis de 9,08 ml L-1 de silicio es la más recomendada para su aplicación.

ABSTRACT In recent years, the use of saline water in agriculture has become an alternative mainly because of water scarcity. However, plants do not tolerate high salt contents; so, the use of salt stress attenuators could enable saline water usage in agriculture. This study aimed to assess the effect of saline water and silicon applications on growth, chloroplastid pigments, chlorophyll fluorescence a and beet production. The experiment was conducted with complete randomized blocks in a 5 x 5 combined factorial arrangement according to the Central Composite of Box experiment matrix for the electrical conductivity in the irrigation water (ECw) and silicon doses (Si), with minimum (- a) and maximum (a) values from 0.5 to 6.0 dS m-1 and from 0.00 to 18.16 mL L-1, totaling nine treatments, with four replicates and three plants per plot. The irrigation water ECw increase reduced growth and beet production, but the chlorophyll contents, biomass and fluorescence production were not affected by salinity. Silicon applications via the soil increased growth and chlorophyll fluorescence a but did not reduce the harmful effect of the salt stress. The irrigation water ECw above 0.50 dS m-1 negatively affected the beet crop. The silicon dose of 9.08 mL L-1 is the most recommended application.