Se describió la composición y estructura florística del bosque amazónico de tierra firme del sector Alto Madera de la provincia centrosureña (fide Navarro). Se instalaron cinco parcelas de una hectárea (100x100 m), entre 140 a 156 m de altitud y geográficamente esta de 9 °55'a 10°19'S y 65°34' a 65°46'O; donde, se evaluaron e identificaron todos los árboles y lianas ≥10 cm de DAP. La densidad registrada fue de 480 (±13) arboles/ha y la diversidad promedio fue 152 (±8) especies/ha, 105 (±4) géneros/ha y 45(±2) familias/ha, basados en la evaluación de 2398 árboles y 137 lianas en 5 ha. La estructura se presentó en forma de J invertida, con mayor cantidad de individuos en las clases menores y a medida que aumenta el tamaño el número de individuos disminuye. En este bosque, las especies de mayor importancia ecológica (IVI) fueron Attalea vel. sp. nov. (palla) y Peltogyne heterophylla (morado), seguida de Euterpe precatoria (asaí), Pseudolmedia laevis (nuí peludo), Tetragastris altissima (isigo colorado), Tachigali vasquezii (palo santo colorado), Brosimun lactescens (quecho verde) y Bertholletia excelsa. En conclusión, el bosque de tierra firme del Alto Madera, es el bosque de mayor diversidad arbórea en Bolivia. No obstante, los valores se encuentran en el rango de diversidad para sus latitudes. Además, presentan composición florística diferente a otros bosques amazónico de tierra firme, la dominancia de la palla (Attalea vel. sp. nov.) y el morado (Peltogyne heterophylla) entre otras especies exclusiva le confieren una particularidad florística y fisionómica a esta formación forestal.

We describe the composition and floristic structure of the terra firme Amazon forest of the Alto Madera sector of the Centro-sureñan province (fide Navarro). Five plots of one hectare (100x100 m) were installed at an altitude of 140 to 156 m at the geographically locale 9 "55' to 10°19'S and 65°34' to 65°46'W; with all trees and lianas ≥ 10 cm diameter measured. The density is 480 (± 13) trees/ha and the diversity is greater than at other sites in Bolivia, with an average of 152 (± 8) species/ha, 105 (± 4) genera/ha and 45 (± 2) families/ha, based on the evaluation of 2398 trees and 137 vines. The structure is pyramidal or in the form of an inverted J, with a greater number of individuals in the smaller classes. In this forest, the most ecologically important species are Attalea sp. nov. (palla) and Peltogyne heterophylla (morado), followed by Euterpe precatoria (asaí), Pseudolmedia laevis (nuí peludo), Tetragastris altissima (isigo colorado), Tachigali vasquezii (palo santo colorado), Brosimum lactescens (quecho verde) y Bertholletia excelsa. In conclusion, the Alto Madera terra firme forest is the forest with the greatest tree diversity in Bolivia. However, the values are in the range of diversity of forests of similar latitudes. In addition, they have a floristic composition different from other Amazon forests of the terra firme, the dominance of the palla (Attalea sp. nov.) and the Purple Heart (Peltogyne heterophylla) among other exclusive species giving this formation a floristic and physiognomic particularity to this forest formation.

Objective: To assess the effectiveness of three mood disorder treatment algorithms in a sample of patients seeking care in the Brazilian public healthcare system. Methods: A randomized pragmatic trial was conducted with an algorithm developed for treating episodes of major depressive disorder (MDD), bipolar depressive episodes and mixed episodes of bipolar disorder (BD). Results: The sample consisted of 259 subjects diagnosed with BD or MDD (DSM-IV-TR). After the onset of symptoms, the first treatment occurred ∼6 years and the use of mood stabilizers began ∼12 years. All proposed algorithms were effective, with response rates around 80%. The majority of the subjects took 20 weeks to obtain a therapeutic response. Conclusions: The algorithms were effective with the medications available through the Brazilian Unified Health System. Because therapeutic response was achieved in most subjects by 20 weeks, a follow-up period longer than 12 weeks may be required to confirm adequate response to treatment. Remission of symptoms is still the main desired outcome. Subjects who achieved remission recovered more rapidly and remained more stable over time. Clinical trial registration: NCT02901249, NCT02870283, NCT02918097