Pesquisa | SciELO

Precisa de ajuda?

Adicionar outro campo +

Histórico de busca

Não foram encontrados documentos para sua pesquisa

Resultados: 46

au:OLIVEIRA, MAURO A.

Filtros

Coleções + Opções

Todos
Brasil

41
Saúde Pública

2
SciELO Preprints

1
Portugal

1
Venezuela

1

Mostrar tudo...

Periódico + Opções

Todos
Arquivos de Neuro-Psiquiatria

6
Journal of the Brazilian Chemical Society

6
Revista Brasileira de Engenharia Agrícola e Ambiental

4
Archives of Endocrinology and Metabolism

3
Arquivos Brasileiros de Endocrinologia & Metabologia

2
Engenharia Agrícola

2
Memórias do Instituto Oswaldo Cruz

2
Química Nova

2
Revista de Saúde Pública

2
Anais da Academia Brasileira de Ciências

1
Archivos Latinoamericanos de Nutrición

1
Bragantia

1
Brazilian Journal of Oceanography

1
Brazilian Journal of Psychiatry

1
Ciência Rural

1

Mostrar tudo...

Idioma

Todos
Português

27

Ano de publicação + Opções

Todos
1993

4
2011

4
2008

3
2016

3
2018

3
1974

2
2001

2
2004

2
2005

2
2010

2
2012

2
2014

2
2015

2
2017

2
1986

1

Mostrar tudo...

SciELO Áreas Temáticas + Opções

Todos
Ciências da Saúde

19
Ciências Agrárias

13
Ciências Exatas e da Terra

9
Ciências Biológicas

4
Engenharias

2
Multidisciplinar

1

WoS Áreas Temáticas + Opções

Todos
Multidisciplinary

13
Chemistry

8
Engineering

7
Psiquiatria

7
Agricultural

6
Medicine

6
Neurociências

6
Sciences

6
Endocrinology

5
Environmental

5
Metabolism

5
Agriculture

4
General

3
Health

3
Internal

3

Mostrar tudo...

WoS Índice de Citações + Opções

Todos
Science Citation Index Expanded

27
Social Sciences Citation Index

8

Citáveis e não citáveis + Opções

Todos
Citável

44
Não citável

1

Tipo de literatura + Opções

Todos
Artigo

41
Artigo de revisão

3
Relato de caso

1
Carta

1

Ordenar por

Página de 4 Próxima

Selecionar esta página

Imprimir | Enviar por e-mail | Exportar |

Facebook
Twitter
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

0 Itens selecionados

Listar itens
Apagar todos da lista

[SciELO Preprints] - Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Marin-Neto, José Antonio Rassi Jr., Anis Moraes Oliveira, Gláucia M. Lemos Correia, Luís Claudio Novaes Ramos Jr., Alberto Hasslocher-Moreno, Alejandro Marcel Luquetti Ostermayer, Alejandro Sousa, Andréa Silvestre de Amato Vincenzo de Paola, Angelo Sobral de Sousa, Antonio Carlos Pinho Ribeiro, Antonio Luiz Correia Filho, Dalmo Moraes de Souza, Dilma do Socorro Cunha-Neto, Edecio J. A. Ramires, Felix Bacal, Fernando Pereira Nunes, Maria do Carmo Martinelli Filho, Martino Ibrahim Scanavacca, Maurício Magalhães Saraiva, Roberto Alves de Oliveira Júnior, Wilson M. Lorga-Filho, Adalberto de Jesus Benevides de Almeida Guimarães, Adriana Lopes Latado Braga, Adriana Sarmento de Oliveira, Adriana V. L. Sarabanda, Alvaro Yecê das Neves Pinto, Ana Assis Lopes do Carmo, André Schmidt, André Costa, Andréa Rodrigues da Ianni, Barbara Maria Markman Filho, Brivaldo Eduardo Rochitte, Carlos Thé Macedo, Carolina Mady, Charles Chevillard, Christophe Bittencourt das Virgens, Cláudio Marcelo Nery de Castro, Cleudson De Paoli de Carvalho Britto, Constança Felícia Pisani, Cristiano do Carmo Rassi, Daniela C. Sobral Filho, Dario Rodrigues Almeida, Dirceu A. Bocchi, Edimar T. Mesquita, Evandro de Souza Nogueira Sardinha Mendes, Fernanda Pereira, Francisca Tatiana Sperandio da Silva, Gilberto Marcelo de Lima Peixoto, Giselle Glotz de Lima, Gustavo H. Veloso, Henrique Turin Moreira, Henrique Bellotti Lopes, Hugo Masciarelli Francisco Pinto, Ibraim Pinto Dias, João Carlos Bemfica, João Marcos Silva-Nunes, João Paulo Soares Barreto-Filho, José Augusto Kerr Saraiva, José Francisco Lannes-Vieira, Joseli Menezes Oliveira, Joselina Luzia V. Armaganijan, Luciana Martins, Luiz Cláudio C. Sangenis, Luiz Henrique Barbosa, Marco Paulo Almeida-Santos, Marcos Antônio Simões, Marcos Vinicius Shikanai-Yasuda, Maria Aparecida Vieira Moreira, Maria da Consolação Higuchi, Maria de Lourdes Costa Monteiro, Maria Rita de Cássia Felix Mediano, Mauro Felippe Maia Lima, Mayara T. Oliveira, Maykon Moreira Dias Romano , Minna Nitz, Nadjar de Tarso Jorge Medeiros, Paulo Vieira Alves, Renato Alkmim Teixeira, Ricardo Coury Pedrosa, Roberto Aras, Roque Morais Torres, Rosália dos Santos Povoa, Rui Manoel Rassi, Sérgio Gabriel Salles Xavier, Sérgio Marinho Martins Alves , Silvia B. N. Tavares, Suelene Lima Palmeira, Swamy da Silva Junior, Telêmaco Luiz da Rocha Rodrigues, Thiago Madrini Junior, Vagner Maia da Costa , Veruska Dutra, Walderez

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Data de publicação: 2022-10-11

Resumo: En Pt

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.nbsp; Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities. nbsp; Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.nbsp; The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.nbsp; The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.nbsp; nbsp;nbsp; Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.

Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.nbsp;nbsp;nbsp; Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.nbsp;

https://doi.org/10.1590/SciELOPreprints.4820

High-resolution semi-automatic mapping based on an Unmanned Aerial Vehicle (UAV) to capture geological structures
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

MOREIRA, JULIO A.

; OLIVEIRA, FABRICIA B. DE

; OLIVEIRA, CARLOS H.R. DE

; FIGUEIREDO, ALVARO C.

; FILHO, MAURO C.L.

; DUARTE, EDUARDO B.

Anais da Academia Brasileira de Ciências

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2021, Volume 93 Nº 3 elocation e20191416

Resumo: En | Texto: En | PDF: En

Abstract Due to the recent technological progress, Unmanned Aerial Vehicles (UAV), is an alternative for the high-resolution imaging of the terrestrial surface, helping map lineaments, essential structures on the stage of geological mapping. Therefore, this research aims to accomplish and to confirm the efficiency of the use of UAV high-resolution imaging for semi-automatic lineament mapping, in a shear zone in Guaçuí/ES. Orthomosaic was created from the UAV imaging, in which the LINE algorithm was used from Geomath PCI software for the semi-automatic mapping of lineaments. In addition, a manual lineament mapping was performed on the orthomosaic for comparison purposes, and a shaded relief image was made up of Azimuth 135° and Elevation 45°, from the SRTM data, followed by manual lineament mapping for a regional vision of the studied area. On the semi-automatic and manual extraction on the orthomosaic and shaded relief image, 61.30%, 61.63%, 57.38% of the lineaments, respectively, have NW-SE direction, showing a really strong correlation. Therefore, the semi-automatic mapping is extremely effective in terms of structural trends acquisition and can provide fine-scale data for the assessment of inaccessible areas.

https://doi.org/10.1590/0001-3765202120191416 201 downloads

Characterization of the Dielectric Properties of the Tommy Atkins Mango
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Silva Júnior, Paulo F.

; Santana, Ewaldo E. C.

; Pinto, Mauro S. Silva

; Andrade, Everson P.

; Carvalho, Joabson N.

; Freire, Raimundo C. S.

; Oliveira, Maciel A.

; Oliveira, Elder E. Carneiro de

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Mar 2020, Volume 19 Nº 1 Páginas 86 - 93

Resumo: En | Texto: En | PDF: En

Abstract This paper presents the characterization of dielectric properties (dielectric permittivity and dielectric loss factor) of Tommy Atkins mango (Mangifera indica L), a fruit produced in several regions of Brazil, of great economic importance. The fruits were characterized according to their maturation index, by probe method, and identified by the yellowish tone in their bark. The results allowed correlating the dielectric characteristics of the fruit with the physicochemical transformations that occurred in the maturation process of the mango Tommy. It was also verified a greater variation in the frequencies below 1 GHz, with the maturation indicated by the dielectric signature on the fifth day after the harvest. From these results, we can observe the use of electromagnetic materials and techniques in the solution and optimization of processes in agriculture can improve the quality of products consumed or suggesting best practices to the productive sector.

https://doi.org/10.1590/2179-10742020v19i11868 674 downloads

Alterações fisiológicas e bioquímicas de sementes de Acacia mangiumWilld. durante o armazenamento
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Pádua, Guilherme V. G. de

; Oliveira, Danilo F. A. de

; Félix, Francival Cardoso

; Macedo, Cristiane E. C. de

; Voigt, Eduardo L.

; Ferrari, Cibele S.

; Pacheco, Mauro V.

Revista de Ciências Agrárias

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Dez 2019, Volume 42 Nº 4 Páginas 141 - 150

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

As sementes estão continuamente expostas ao processo de deterioração, o qual envolve alterações fisiológicas, bioquímicas, físicas e citológicas. Assim, este estudo teve por objetivo avaliar alterações fisiológicas e bioquímicas em sementes de Acacia mangium durante o armazenamento em três ambientes. Para este fim, as sementes foram armazenadas em sacos de polietileno semipermeáveis durante os períodos de 0, 3, 6, 9, 12 e 15 meses em três condições de armazenamento: congelador (T = -20 ± 3 ºC; U.R. = 49 ± 15%), frigorífico doméstico (T = 6 ± 3 ºC; U.R. = 55 ± 14%) e sala climatizada (T = 27 ± 4 ºC; U.R. = 56 ± 13%). Foram realizadas as seguintes determinações e testes: teor de água, germinação, primeira contagem de germinação, índice de velocidade de germinação, massa seca de plântulas, emergência, índice de velocidade de emergência, açúcares solúveis totais, açúcares não redutores, aminoácidos livres totais, amido e proteínas solúveis. As sementes de A. mangium conservam a qualidade fisiológica durante 12 meses quando armazenadas quer em congelador, frigorífico doméstico ou sala climatizada. Não foi possível verificar um padrão de alteração no conteúdo de amido, açúcares solúveis totais e açúcares não redutores.

Seeds are continually exposed to the deterioration process, which involves physiological, biochemical, physical and cytological changes. Thus, the objective of this study was to evaluate physiological and biochemical changes in Acacia mangium seeds during storage in three environments. For this purpose, the seeds were stored in semi-permeable polyethylene bags during periods of 0, 3, 6, 9, 12 and 15 months under three conditions: frezer (T = -20 ± 3 ºC, RH = 49 ± 15%), refrigerator (T = 6 ± 3 °C, RH = 55 ± 14%) and air-conditioned room (T = 27 ± 4 °C, RH = 56 ± 13%). The following determinations and tests were performed: water content, germination, first germination count, germination speed index, seedling dry mass, emergence rate, emergence speed index, total soluble sugars, non-reducing sugars, total free amino acids, starch and soluble proteins. The seeds of A. mangium retain the physiological quality for 12 months when stored in a frezer, domestic refrigerator and heated room. It was not possible to verify a pattern of change in the content of starch, total soluble sugars and non-reducing sugars.

https://doi.org/10.19084/rca.17552 296 downloads

Doenças do sistema nervoso central de bezerros no sul do Rio Grande do Sul: uma contribuição ao diagnóstico diferencial
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Santos, Bianca L.

; Estima-Silva, Pablo

; Coelho, Ana Carolina B.

; Oliveira, Plinio A.

; Soares, Mauro P.

; Sallis, Eliza S.V.

; Bruhn, Fabio R.P.

; Schild, Ana Lucia

Pesquisa Veterinária Brasileira

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Abr 2018, Volume 38 Nº 4 Páginas 685 - 691

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: Este estudo teve o objetivo de determinar a frequência das enfermidades do sistema nervoso central que afetam bezerros até 12 meses de idade na região sul do Rio Grande do Sul. Foi realizado um estudo retrospectivo estabelecendo-se as principais enfermidades observadas nesta categoria de bovinos em um período de 36 anos. Foram revisados os protocolos de necropsia e de materiais remetidos ao Laboratório Regional de Diagnóstico da Faculdade de Veterinária da Universidade Federal de Pelotas entre janeiro de 1978 e dezembro de 2015 referentes aos bovinos até 12 meses de idade que apresentavam sinais neurológicos. Foram resgatados os dados epidemiológicos referentes à procedência dos animais, tipo de criação, raça, idade e época de ocorrência e frequência de cada enfermidade. Foram identificados 615 casos de bovinos com sinais neurológicos, dos quais 162 (26,3%) tinham até 12 meses de idade. Os diagnósticos foram agrupados por etiologia, sendo que as enfermidades virais totalizaram 42,6% dos casos; as doenças bacterianas 19,1% e as doenças parasitárias 17,3%. Os defeitos congênitos e as doenças hereditárias representaram 6,2% dos casos, seguidos pelas intoxicações e micotoxicoses com 4,9%; pelas doenças carenciais e multifatoriais ambas com 2,5% dos casos e pelos traumatismos com 1,9%, doenças degenerativas e neoplasias com 0,6% dos diagnósticos. Os casos inconclusivos representaram 1,86% do total. Nos bezerros até os 90 dias as principais enfermidades foram os defeitos congênitos e as meningites e encefalites por causas bacterianas, além dos abscessos do sistema nervoso central; nos bezerros entre os quatro e nove meses as enfermidades tiveram uma frequência mais baixa destacando-se apenas a raiva. A partir dos 10 até os 12 meses a babesiose, a raiva e a encefalite por herpesvírus bovino foram as mais importantes como causa de morte.

ABSTRACT: This paper aimed to determine the frequency of diseases of the central nervous system affecting calves under 12 months of age in southern Rio Grande do Sul. A retrospective study was conducted determining the main diseases observed in this category of cattle over a period of 36 years. We reviewed all the necropsy protocols and materials sent to the laboratory between 1978 and December 2015 relating to cattle under 12 months of age that showed neurological signs. The epidemiological data concerning the origin of the animals, raising system, breed, age and time of occurrence of each disease and frequency were taken from necropsy protocols. Out of 615 cases with neurological signs, 162 (26.3%) corresponded to cattle with age up to 12 months. The diagnoses were grouped by etiology of viral diseases (42.6%), bacterial diseases (19.1%), parasitic diseases (17.3%), congenital defects, hereditary diseases (6.2%), poisoning, mycotoxicoses (4.9%), nutritional deficiency and multifactorial diseases (2.5%), and trauma, degenerative diseases and neoplasms with 0.62% of diagnoses. Inconclusive cases represented 1.9% of the total diagnosed. In 1 to 90 day-old calves the main diseases observed were congenital defects, meningitis and encephalitis caused by bacteria. Central nervous system abscesses were also observed. In 4 to 9 month-old calves a lower frequency of disease were noted. Rabies was the most important disease diagnosed in this category. Babesiosis, rabies and encephalitis by bovine herpesvirus were the most important causes of death in 10 to 12 month-old calves.

https://doi.org/10.1590/1678-5150-pvb-5360 7015 downloads

Controversial issues in the management of hyperprolactinemia and prolactinomas – An overview by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Vilar, Lucio

; Abucham, Julio

; Albuquerque, José Luciano

; Araujo, Luiz Antônio

; Azevedo, Monalisa F.

; Boguszewski, Cesar Luiz

; Casulari, Luiz Augusto

; Cunha Neto, Malebranche B. C.

; Czepielewski, Mauro A.

; Duarte, Felipe H. G.

; Faria, Manuel dos S.

; Gadelha, Monica R.

; Garmes, Heraldo M.

; Glezer, Andrea

; Gurgel, Maria Helane

; Jallad, Raquel S.

; Martins, Manoel

; Miranda, Paulo A. C.

; Montenegro, Renan M.

; Musolino, Nina R. C.

; Naves, Luciana A.

; Ribeiro-Oliveira Júnior, Antônio

; Silva, Cíntia M. S.

; Viecceli, Camila

; Bronstein, Marcello D.

Archives of Endocrinology and Metabolism

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Mar 2018, Volume 62 Nº 2 Páginas 236 - 263

Resumo: En | Texto: En | PDF: En

ABSTRACT Prolactinomas are the most common pituitary adenomas (approximately 40% of cases), and they represent an important cause of hypogonadism and infertility in both sexes. The magnitude of prolactin (PRL) elevation can be useful in determining the etiology of hyperprolactinemia. Indeed, PRL levels > 250 ng/mL are highly suggestive of the presence of a prolactinoma. In contrast, most patients with stalk dysfunction, drug-induced hyperprolactinemia or systemic diseases present with PRL levels < 100 ng/mL. However, exceptions to these rules are not rare. On the other hand, among patients with macroprolactinomas (MACs), artificially low PRL levels may result from the so-called “hook effect”. Patients harboring cystic MACs may also present with a mild PRL elevation. The screening for macroprolactin is mostly indicated for asymptomatic patients and those with apparent idiopathic hyperprolactinemia. Dopamine agonists (DAs) are the treatment of choice for prolactinomas, particularly cabergoline, which is more effective and better tolerated than bromocriptine. After 2 years of successful treatment, DA withdrawal should be considered in all cases of microprolactinomas and in selected cases of MACs. In this publication, the goal of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism (SBEM) is to provide a review of the diagnosis and treatment of hyperprolactinemia and prolactinomas, emphasizing controversial issues regarding these topics. This review is based on data published in the literature and the authors' experience.

https://doi.org/10.20945/2359-3997000000032 36158 downloads

A review of Cushing's disease treatment by the Department of Neuroendocrinology of the Brazilian Society of Endocrinology and Metabolism
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Machado, Márcio Carlos

; Fragoso, Maria Candida Barisson Vilares

; Moreira, Ayrton Custódio

; Boguszewski, César Luiz

; Vieira Neto, Leonardo

; Naves, Luciana A.

; Vilar, Lucio

; Araújo, Luiz Antônio de

; Musolino, Nina Rosa Castro

; Miranda, Paulo Augusto C.

; Czepielewski, Mauro A.

; Gadelha, Monica R.

; Bronstein, Marcello Delano

; Ribeiro-Oliveira Jr., Antônio

Archives of Endocrinology and Metabolism

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Fev 2018, Volume 62 Nº 1 Páginas 87 - 105

Resumo: En | Texto: En | PDF: En

ABSTRACT The treatment objectives for a patient with Cushing's disease (CD) are remission of hypercortisolism, adequate management of co-morbidities, restoration of the hypothalamic-pituitary-adrenal axis, preservation of fertility and pituitary function, and improvement of visual defects in cases of macroadenomas with suprasellar extension. Transsphenoidal pituitary surgery is the main treatment option for the majority of cases, even in macroadenomas with low probability of remission. In cases of surgical failure, another subsequent pituitary surgery might be indicated in cases with persistent tumor imaging at post surgical magnetic resonance imaging (MRI) and/or pathology analysis of adrenocorticotropic hormone-positive (ACTH+) positive pituitary adenoma in the first procedure. Medical treatment, radiotherapy and adrenalectomy are the other options when transsphenoidal pituitary surgery fails. There are several options of medical treatment, although cabergoline and ketoconazole are the most commonly used alone or in combination. Novel treatments are also addressed in this review. Different therapeutic approaches are frequently needed on an individual basis, both before and, particularly, after surgery, and they should be individualized. The objective of the present review is to provide the necessary information to achieve a more effective treatment for CD. It is recommended that patients with CD be followed at tertiary care centers with experience in treating this condition.

https://doi.org/10.20945/2359-3997000000014 5266 downloads

Strategies for Molecular Diversification of 2-[Aminoalkyl-(1H-1,2,3-triazol-1- yl)]-1,4-naphthoquinones Using Click Chemistry
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira,, Ronaldo N. de

; Silva,, Mauro G. da

; Silva,, Moara Targino da

; Melo, Valentina N.

; Valença, Wagner O.

; Paz, Josinete Angela da

; Camara, Celso A.

Journal of the Brazilian Chemical Society

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Abr 2017, Volume 28 Nº 4 Páginas 681 - 688

Resumo: En | Texto: En | PDF: En

Click chemistry-based strategies for the synthesis of 2-amino-alkyl-1,2,3-triazole-1,4-naphthoquinone derivatives make it possible to obtain desired products from 1,4-naphthoquinone (1,4-NQ), and bio-based lawsone, nor-lapachol and lapachol. The first route (Strategy A) starting from 1,4-NQ and amino alcohols, then 2-amino-alkyl-1,4-NQ alcohols, were tosylated. The azide ion displaced the tosylate group to afford 2-azide-alkyl-1,4-NQ, which was submitted to a copper-catalyzed azide alkyne cycloaddition (CuAAC) condition. The triazole-naphthoquinones were obtained in an overall yield of roughly 47%. Another pathway (Strategy B) substituted bromo-alkyl-phthalimides using NaN3 as the nucleophile, sequential CuAAC and deprotection of phthalimide group with hydrazine producing amino-triazoles. The subsequent reaction with 1,4-NQ produced 2-amino-alkyl-1,2,3-triazole-1,4-NQ derivatives in an overall yield of 45-76% in four steps. After we developed these two strategies, linear synthesis (Strategy A) was chosen to prepare 2-[(2-(1H-1,2,3-triazol-1-yl)ethylamino)]-3-(3-methylpropenyl)-1,4-naphthoquinones from lawsone with an overall yield of approximately 27% in six steps. On the other hand, convergent synthesis (Strategy B) was employed for the synthesis of 2-[(4-phenyl-1H-1,2,3-triazol-1-yl)alkyl-amino)]-3-(3-methylbut-2-en-1-yl)-1,4-naphthoquinones from the reaction between 2-methoxy-lapachol with amino-triazoles with a global yield of about 21%. These synthetic strategies might lead us to new opportunities to build small-molecule libraries for future biological exploration.

https://doi.org/10.21577/0103-5053.20160207 1122 downloads

Cessation of dangerousness status: an analysis of 224 reports from the Instituto de Perícias Heitor Carrilho, Rio de Janeiro, Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira, Gustavo C.

; Valença, Alexandre M.

; de Moraes, Talvane M.

; Mendlowicz, Mauro V.

; Forrest, Miles C.

; Batista, Fred F.

; Mendes, Gabriella A.

; Lima, Tiago N.

; Gonçalves, Vinicius R.

; Mecler, Kátia

Brazilian Journal of Psychiatry

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Mar 2017, Volume 39 Nº 1 Páginas 45 - 54

Resumo: En | Texto: En | PDF: En

Objectives: To evaluate factors related to dangerousness cessation at the end of involuntary commitment based on an analysis of expert reports. In light of the current legal requirement of dangerousness cessation as a pre-requisite for prison or internment release of individuals subjected to the safety measure, we sought elements to reflect on the practice of expert examiners in charge of making this decision. Methods: The authors revised 224 expert psychiatric dangerousness cessation reports released 2011 through 2014 and collected data for a statistical analysis. Results: The following variables were associated with positive risk cessation assessments: no inadequate behavior (according to the assistant professionals), no productive psychotic symptoms, no negative symptoms, presence of insight, presence of a support network, and no psychoactive substance abuse. The following variables were associated with negative dangerousness cessation decisions: early onset of malfunction, lack of insight, negative attitudes, active signs of major mental illness, presence of impulsiveness, poor response to treatment, presence of plans lacking feasibility, exposure to destabilizing factors, lack of personal support, and presence of stress. Conclusions: In this study we were able to identify factors associated with dangerousness in a sample of expert reports. The knowledge of factors linked to a higher risk of recidivism in illegal activities or violent behavior is crucial for decision-making regarding the release of offenders after their legally established period of involuntary commitment.

https://doi.org/10.1590/1516-4446-2015-1871 1355 downloads

10.

Recommendations of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism for the diagnosis of Cushing’s disease in Brazil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Machado, Márcio Carlos

; Fragoso, Maria Candida Barisson Vilares

; Moreira, Ayrton Custódio

; Boguszewski, César Luiz

; Vieira Neto, Leonardo

; Naves, Luciana A.

; Vilar, Lucio

; Araújo, Luiz Antônio de

; Czepielewski, Mauro A.

; Gadelha, Monica R.

; Musolino, Nina Rosa Castro

; Miranda, Paulo Augusto C.

; Bronstein, Marcello Delano

; Ribeiro-Oliveira Jr., Antônio

Archives of Endocrinology and Metabolism

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2016, Volume 60 Nº 3 Páginas 267 - 286

Resumo: En | Texto: En | PDF: En

ABSTRACT Although it is a rare condition, the accurate diagnosis and treatment of Cushing’s disease is important due to its higher morbidity and mortality compared to the general population, which is attributed to cardiovascular diseases, diabetes mellitus and infections. Screening for hypercortisolism is recommended for patients who present multiple and progressive clinical signs and symptoms, especially those who are considered to be more specific to Cushing’s syndrome, abnormal findings relative to age (e.g., spinal osteoporosis and high blood pressure in young patients), weight gain associated with reduced growth rate in the pediatric population and for those with adrenal incidentalomas. Routine screening is not recommended for other groups of patients, such as those with obesity or diabetes mellitus. Magnetic resonance imaging (MRI) of the pituitary, the corticotropin-releasing hormone (CRH) test and the high-dose dexamethasone suppression test are the main tests for the differential diagnosis of ACTH-dependent Cushing’s syndrome. Bilateral and simultaneous petrosal sinus sampling is the gold standard method and is performed when the triad of initial tests is inconclusive, doubtful or conflicting. The aim of this article is to provide information on the early detection and establishment of a proper diagnosis of Cushing’s disease, recommending follow-up of these patients at experienced referral centers. Arch Endocrinol Metab. 2016;60(3):267-86

https://doi.org/10.1590/2359-3997000000174 6344 downloads

11.

Ecophysiological leaf traits of native and exotic palm tree species under semi-arid conditions
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Oliveira, Deborah

; Medeiros, Maria

; Pereira, Silvia

; Oliveira, Marciel

; Frosi, Gabriella

; Arruda, Emília

; Santos, Mauro

Bragantia

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jun 2016, Volume 75 Nº 2 Páginas 128 - 134

Resumo: En | Texto: En | PDF: En

ABSTRACT The main goal of this study was to evaluate the performance of two palm species under semi-arid conditions during the rainy and dry periods: the semi-arid native Syagrus coronata and a native to tropical America, Acrocomia aculeata. The leaf water potential, gas exchange, leaf soluble sugars, starch, free amino acids, total soluble protein content and morphological traits were measured. The highest leaf water potential and CO2 assimilation values in both species were achieved during the rainy period. In response to the low soil moisture content during the dry period, gas exchange decreased 72 and 92% in S. coronata and A. aculeata, respectively, when compared with values from rainy period. As evergreen plants, both species maintained intact leaf photosynthetic pigment contents during the rainy and dry periods. Other important traits for drought tolerance are larger adaxial surface hypoderm and cuticle found in both species with higher stomatal density on the abaxial leaf surface. When comparing the species, S. coronata exhibited lower sensitivity to low water availability, showing higher CO2assimilation and water use efficiency.

https://doi.org/10.1590/1678-4499.364 5388 downloads

12.

Brazilian coral reefs in a period of global change: A synthesis
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Leão, Zelinda M. A. N.

; Kikuchi, Ruy K. P.

; Ferreira, Beatrice P.

; Neves, Elizabeth G.

; Sovierzoski, Hilda H.

; Oliveira, Marília D. M.

; Maida, Mauro

; Correia, Monica D.

; Johnsson, Rodrigo

Brazilian Journal of Oceanography

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

2016, Volume 64 Nº spe2 Páginas 97 - 116

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Os recifes de coral do Brasil formam estruturas significativamente diferentes dos modelos conhecidos: (i) possuem uma forma de crescimento de pináculos coralíneos em forma de cogumelo, chamados "chapeirões", (ii) são construídos por uma fauna coralínea com baixa diversidade e rica em espécies endêmicas, sendo grande parte destas formas relíquias do período Terciário e (iii) os recifes costeiros estão num ambiente dominado por sedimentos siliciclásticos. Os recifes estão distribuídos em quatro áreas ao longo da costa brasileira: regiões norte, nordeste, leste, e nas ilhas oceânicas, mas espécies isoladas de coral podem ser encontradas em águas mais quentes nas enseadas da região sul. Diferentes tipos de banco recifais, recifes em franja, "chapeirões" isolados e um atol estão presentes ao longo da costa brasileira. Corais, milleporídeos e algas coralinas incrustantes constroem a estrutura rígida dos recifes. As áreas em que ocorrem os maiores recifes de coral correspondem às regiões nas proximidades de centros urbanos que estão experimentando crescimento acelerado e rápido desenvolvimento do turismo. Os principais efeitos antropogênicos sobre o ecossistema recifal estão associados, essencialmente ao aumento da sedimentação devido à remoção da mata atlântica e as descargas de efluentes industriais e urbanos. Os efeitos do aquecimento das águas oceânicas que vem afetando várias áreas de recifes, com alta intensidade de branqueamento de coral, não causaram mortalidade em massa nos recifes brasileiros até o evento de 2010.

Abstract Brazilian coral reefs form structures significantly different from the well-known reef models, as follows: (i) they have a growth form of mushroom-shaped coral pinnacles called "chapeirões", (ii) they are built by a low diversity coral fauna rich in endemic species, most of them relic forms dating back to the Tertiary, and (iii) the nearshore bank reefs are surrounded by siliciclastic sediments. The reefs are distributed in the following four major sectors along the Brazilian coast: the northern, the northeastern and the eastern regions, and the oceanic islands, but certain isolated coral species can be found in warmer waters in embayments of the southern region. There are different types of bank reefs, fringing reefs, isolated "chapeirões" and an atoll present along the Brazilian coast. Corals, milleporids and coralline algae build the rigid frame of the reefs. The areas in which the major coral reefs occur correspond to regions in which nearby urban centers are experiencing accelerated growth, and tourism development is rapidly increasing. The major human effects on the reef ecosystem are mostly associated with the increased sedimentation due to the removal of the Atlantic rainforest and the discharge of industrial and urban effluents. The effects of the warming of oceanic waters that had previously affected several reef areas with high intensity coral bleaching had not shown, by the time of the 2010 event, any episodes of mass coral mortality on Brazilian reefs.

https://doi.org/10.1590/S1679-875920160916064sp2 10789 downloads

13.

Static tests of constructive tires using hydraulic press on the soil
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Machado, Thiago M.

; Lanças, Kléber P.

; Oliveira Junior, Mauro B. de

; Artioli, José A.

; Marasca, Indiamara

Engenharia Agrícola

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Out 2015, Volume 35 Nº 5 Páginas 886 - 893

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO A potência e a capacidade de carga das máquinas agrícolas vêm crescendo, e os efeitos da pressão imposta no solo, por meio dos pneus, ainda são pouco estudados. Com o desenvolvimento sustentável, a relação máquina-pneu-solo deve ser criteriosamente avaliada para que haja um melhor equilíbrio entre esses elementos. Este trabalho teve por objetivo avaliar quatro pneus com dois tipos construtivos: o diagonal cinturado BPAF (Baixa Pressão e Alta Flutuação) e o radial, ambos com diâmetros de aro de 572 e 673 mm, sendo determinadas as seguintes variáveis: área de contato pneu/superfície da amostra do solo, deformação elástica do pneu, recalque e resistência mecânica à penetração da amostra em caixa de solo. Foi utilizada uma prensa hidráulica que possuía um eixo de fixação para montagem dos pneumáticos e uma caixa de solo na qual o pneu foi prensado com uma carga de 53,00 kN, utilizando as pressões nominais recomendadas pelo fabricante dos pneumáticos. O pneu de construção radial, com diâmetro de aro 673 mm, obteve menores recalque e resistência à penetração, maior deformação elástica e área de contato em relação aos demais pneumáticos, enquanto BPAF, aro 572 mm, apresentou a maior resistência à penetração e a menor deformação elástica.

ABSTRACT The power consumption and load capacity of agricultural machines have grown and the effects of pressure on the soil by tires have been still little investigated. In concern with sustainable development, the relationship machine-tire-soil must be in balance to give more consistency on the best use of tires for a given load. This study aimed to evaluate four tires of two constructive types, the bias belted tires and radial tires, both with respective rim diameters of 22.5 and 26.5 inches with variables measuring the footprint, elastic deformation, sinkage and resistance to penetration. A hydraulic press with an attachment shaft for tire mounting and a box of soil in which the tire has been imposed on a load of 53.00 kN using nominal pressures recommended by the tire manufacturer. The radial construction tire with rim diameter of 26.5 inches obtained less sinkage and resistance to penetration; however, greater elastic deformation and footprint compared to other tires. The bias-belted tire with 22.5-inch rim presented the highest resistance to penetration and the lowest elastic deformation.

https://doi.org/10.1590/1809-4430-Eng.Agric.v35n5p886-893/2015 1460 downloads

14.

A INFLUÊNCIA DA LIGAÇÃO DE HIDROGÊNIO EM REAÇÕES QUÍMICAS: REAÇÃO DE PRILESCHAJEW
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Bueno, Mauro A.

; Oliveira, Boaz G.

Química Nova

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Jan 2015, Volume 38 Nº 1 Páginas 1 - 7

Resumo: Pt | Texto: Pt | PDF: Pt

Theoretical analysis at the BHandHLYP/6-311++G(d,p) level of theory with the support of QTAIM calculations was used to reinvestigate the structure of an intermolecular system formed between ethylene oxide (C2H4O) and formic acid (HCO2H) after the epoxidation known as the Prileschajew reaction. Geometric and infrared vibration results revealed that HO2CH forms a strong hydrogen bond with C2H4O followed by a larger red-shift of the H−O bond. NBO analysis was applied to justify this frequency shift. Finally, QTAIM calculations identified the formation of two hydrogen bonds, namely O···H−O and H···O=C.

https://doi.org/10.5935/0100-4042.20140296 2362 downloads

15.

Electrochemical study of simple coumarin and its determination in aqueous infusion of Mikania glomerata
Facebook Twitter

Outras redes sociais
Google+
LinkedIn
Reddit
StambleUpon
CiteULike
Mendeley
Outras redes

Métricas
- SciELO Analytics
- Dimensions
- PlumX
- Altmetric

Miyano, Daniela M.

; Lima, Thays

; Simões, Fábio R.

; La-Scalea, Mauro A.

; Oliveira, Hueder P. M.

; Codognoto, Lucia

Journal of the Brazilian Chemical Society

Métricas do periódico
- Sobre o periódico
- SciELO Analytics

Mar 2014, Volume 25 Nº 3 Páginas 602 - 609

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

O presente estudo teve por objetivos o desenvolvimento e a aplicação de um método eletroquímico para a determinação da cumarina simples em meio aquoso utilizando o eletrodo de diamante dopado com boro (BDDE). Os estudos foram realizados em pH 8,0 utilizando a voltametria cíclica (CV) e observou-se um processo de redução irreversível controlado por difusão com um pico de redução em torno de -1,6 V. Entretanto, foi possível observar por voltametria de onda quadrada (SWV) que no mesmo pH a redução da cumarina possui um caráter reversível. Além disso, esta reversibilidade se tornou mais evidente com o aumento do pH da solução. Um estudo cronoamperométrico mostrou que o processo de redução da cumarina envolve dois elétrons. A partir dos parâmetros otimizados da SWV uma curva analítica foi construída no intervalo linear de 0,5 × 10-5 a 10,0 × 10-5 mol L-1. Os limites de detecção e de quantificação foram 1,5 × 10-6 mol L-1 e 4,5 × 10-6 mol L-1, respectivamente. A cumarina foi determinada em amostras de Mikania glomerata (infusão aquosa) com valores de recuperação entre 92 e 104%.

The present study aims the development and application of an electrochemical method for simple coumarin determination in aqueous media by using a boron-doped diamond electrode (BDDE). The studies were carried out at pH 8.0 by cyclic voltammetry (CV) and registered an irreversible reduction process controlled by diffusion with the peak potential recorded around -1.6 V. The square wave voltammetry analysis (SWV) showed the reversible behavior of the electrochemical reduction of coumarin at the same pH. Additionally, the reversibility of the process was improved by increasing the solution pH. The chronoamperometry study showed that the coumarin reduction process involves two electrons. From the optimized SWV parameters, the analytical curve was constructed in a linear range between 0.5 × 10-5 and 10.0 × 10-5 mol L-1. The limits of detection and quantification were 1.5 × 10-6 mol L-1 and 4.5 × 10-6 mol L-1, respectively. The coumarin was determined in an aqueous infusion of Mikania glomerata, showing recovery values between 92 and 104%.

https://doi.org/10.5935/0103-5053.20140046 2856 downloads

Exibindo

itens por página

Página de 4 Próxima

Selecione um ou mais resultados

Todos Ordem alfabética

Resultados

Gráfico comparativo Download CSV

Visualizar estatísticas de

Enviar resultado

E-mail do(s) destinatários*

Utilize ; (ponto e vírgula) para mais de um e-mail.

Enviar por e-mail

Esta página

Registros selecionados

Todos os registros (max. 300)

Alterar remetente, assunto e comentários

Seu email

Assunto

Comentários

Alterar remetente, assunto e comentários

Exportar resultados

Formato de exportação:

RIS (para EndNote, ProCite, Reference Manager, RefWorks, Citavi, etc.)

BibTeX

Citação

CSV (para Excel, etc)

Exportar:

Esta página

Itens selecionados

Todos os registros (max. 2000)

Mostrar mais

Sem resultados

Não foram encontrados documentos para sua pesquisa

Glossário e ajuda para busca

Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

SciELO - Scientific Electronic Library Online
Rua Dr. Diogo de Faria, 1087 – 9º andar – Vila Clementino 04037-003 São Paulo/SP - Brasil
Email: scielo@scielo.org

Todo o conteúdo de www.scielo.org, exceto onde está identificado, está licenciado sob uma Licença Creative Commons.
saiba mais »