Abstract: Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that allows visualization of the epidermis and papillary dermis with cellular-level resolution. Granulomatous reactions such as sarcoidosis could be assessed using RCM. The identification of bright beaded-like structures that could correspond to reticulin fibers overlying granulomas, in association with dermoscopy, may be a very useful approach in the diagnosis of sarcoidosis and for the differentiation of this granulomatous entity with superficial cutaneous metastasis.

El cáncer de piel es la malignidad más frecuente. Si bien nuestro país no cuenta con estadísticas sobre su incidencia, la distribución entre los carcinomas de piel (carcinomas basocelulares, carcinomas espinocelulares, melanoma maligno) es similar a la reportada en países anglosajones. Entre las diversas modalidades terapéuticas está la criocirugía, de la cual nuestro centro es pionero a nivel mundial. Su uso con finalidad paliativa en el tratamiento de lesiones de gran tamaño, deformantes, recidivantes o metastásicas abre una puerta adicional en el manejo de pacientes donde las opciones son tan escasas, logrando mejorarles la calidad de vida.

Skin cancer is the most common malignancy. Venezuela does not have proper statistical figures on the subject; however, its distribution among the most frequent skin malignancies-basal and squamous cell carcinomas, malignant melanomas- is similar to the one in northern hemisphere countries. Cryosurgery stands among the different surgical options, being our center pioneer worldwide in the use of it. Applying it as palliation in large, disfiguring, recurrent or metastatic tumors opens an additional alternative in patients where options are scarse.