Abstract Background The association between lipoprotein levels and late-onset neonatal sepsis has shown controversial results. The aims are to assess lipid profile, cytokines, and Monocyte-to-HDL (M/H) ratio as diagnostic and prognostic markers for late-onset neonatal sepsis. Methods This prospective study included 49 septic neonates and 17 controls. Cholesterol (CT), Triglyceride (TG), Very-Low-Density (VLDLc), Low-Density (LDLc), and High-Density Lipoproteins (HDLc) were measured at admission (D0) and on days 3, 7 and 10 to evaluate septic shock outcomes. Cytokines and monocytes were evaluated by flow cytometry. Results Septic newborns showed higher IL-6 and IL-8 at D0 and CT levels on D7 and on D10, which also presented higher TG, VLDLc and non-HDL cholesterol concentrations than controls. The septic shock group (n = 22) revealed a higher number of male subjects, CRP, IL-6, IL-8 and IL-10 levels, while lower TG, HDLc, monocyte numbers and M/H ratio at admission compared to the non-shock group (n = 27). M/H ratio and non-HDL cholesterol on D0 were risk factors for septic shock (OR = 0.70, 0.49‒0.99; OR = 0.96, 0.92‒0.99, respectively). Decreasing levels from D0 to D3 of CT (OR = 0.96, 0.93‒0.99), VLDLc (OR = 0.91, 0.85‒0.98), and non-HDL cholesterol (OR = 0.92, 0.87‒0.98) were also predictors of septic shock. Conclusions Lower M/H ratios and non-HDL cholesterol at admission and decreasing levels of cholesterol, VLDLc and non-HDL cholesterol during a hospital stay are associated with the development of septic shock in newborns with late-onset neonatal sepsis.

RESUMO Neste trabalho, foi realizado o tratamento do lixiviado de um aterro urbano por meio de uma combinação dos processos de coagulação/floculação e adsorção. O lixiviado empregado foi coletado no aterro de resíduos sólidos urbanos da Muribeca (PE) e coagulado com cal. O objetivo foi avaliar o uso do pó de ostra como adsorvente. Os experimentos de adsorção foram realizados em batelada, utilizando as melhores condições para a ativação e para o processo por intermédio de dois planejamentos experimentais. Em seguida, foram realizados os estudos cinéticos e de equilíbrio e uma avaliação de cada etapa do processo. O tempo de equilíbrio foi de 40 min. As isotermas de adsorção seguiram o modelo de Langmuir e a capacidade máxima de adsorção foi de 45,45 Hazen.L.g-1. A combinação dos processos de tratamento em questão foi bastante eficiente, obtendo reduções de aproximadamente 95% da demanda bioquímica de oxigênio (DBO), 40% da demanda química de oxigênio (DQO) e 70% da cor do lixiviado.

ABSTRACT In this work the leachate treatment of an urban landfill was carried out through a combination of coagulation/flocculation and adsorption processes. The leachate employed was collected in the municipal solid waste landfill of Muribeca-PE and coagulated with lime. The objective was to evaluate the use of oyster powder as adsorbent. The adsorption experiments were performed in batch using the best conditions for activation and process through two experimental designs. Then, the kinetic and equilibrium studies were carried out as well as an evaluation of each stage of the process. The equilibrium time was 40 min. Adsorption isotherms followed the Langmuir model and the maximum adsorption capacity was 45.45 Hazen.L.g-1. The combination of the treatment processes in question was very efficient, achieving a reduction of approximately 95% DBO, 40% COD, 70% of the leachate color.

ABSTRACT The treatment of large scalp defects remains a big challenge, even though several therapeutic options are available. According to localization, size and depth of injury, and patient’s characteristics, the plastic surgeon may use techniques such as skin graft, tissue expanders, local or free flaps. Microsurgery has revolutionized reconstructive plastic surgery and is the gold standard for more complex cases. However, it is available only in large centers. Using the simplest technique is a broadly accepted concept that should be applied to scalp wounds as well. In this paper, we report a case of trauma of a 4 year-old child who lost approximate one third of the scalp including pericranium areas, that it is possible to reconstruct the scalp by rotating a supragaleal flap followed by a skin graft over the galea. This is an easily reproducible technique with a short learning curve, and therefore is an interesting option for large scalp injuries.

RESUMO O tratamento de grandes defeitos no couro cabeludo permanece um desafio, a despeito de muitas opções terapêuticas. De acordo com a localização, tamanho e profundidade da lesão, assim como características do paciente, o cirurgião plástico poderá optar dentre inúmeras técnicas com graus variados de complexidade, como enxertos de pele, expansores teciduais, retalhos locais ou livres, entre outras. A microcirurgia revolucionou a cirurgia plástica reparadora e se configura como padrão ouro de tratamento em casos complexos, no entanto, está disponível apenas nos grandes centros. Observando essa limitação, devemos nos ater ao preceito da escada reconstrutora, que prioriza uso da técnica mais simples possível e também deve ser aplicada em casos de ferimentos de escalpo. Nesse artigo demonstramos, em um caso de traumatismo numa menina de 4 anos de idade com perda de aproximadamente um terço do escalpo incluindo áreas de pericrânio, que é possível a reconstrução do couro cabeludo com a rotação de um retalho supragaleal seguida de enxertia de pele parcial sobre a gálea. Essa é uma técnica reprodutível e com curta curva de aprendizado, sendo uma opção bastante interessante para esses casos.

A presente pesquisa teve como objetivo construir e validar uma escala de valores sociomorais que mensurou a presença e o modo de adesão aos valores de justiça, respeito, solidariedade e convivência democrática em estudantes e professores da educação básica em escolas públicas e privadas de São Paulo (10.011 participantes). A metodologia envolveu a elaboração de histórias com alternativas pró e contravalor em três níveis de perspectiva social, a aplicação de questionário na amostra e o processamento dos dados com o uso da Teoria de Resposta ao Item - TRI -, segundo o modelo para itens politômicos. Como resultados, apresentam-se as classificações dos participantes em níveis estabelecidos por valor e discutem-se as implicações educacionais da pesquisa.

This study aimed to construct and validate a socio-moral values scale to measure the presence and commitment to the values of justice, respect, solidarity and democratic coexistence of students and teachers in Basic Education in public and private schools in São Paulo (10,011 participants). The methodology involved the development of stories with pro and con alternatives at three levels of social perspective, as well as the application of a questionnaire to the sample and data processing using the Item Response Theory model for polytomous items. As a result, the classification of participants in standards set by value is presented and some educational implications of the research are discussed.

Este estudio tuvo el objetivo de construir y validar una escala de valores sociomorales que mide la presencia y la adhesión a los valores de justicia, respeto, solidaridad y convivencia democrática en los estudiantes y profesores de educación básica en las escuelas públicas y privadas en São Paulo (10.011 participantes). La metodología consistió en la elaboración de historias con alternativas favorables y contrarias en tres niveles de la perspectiva social, en la aplicación del cuestionario en la muestra y en el procesamiento de los datos con el uso de la Teoría de Respuesta al Ítem en el modelo para los artículos politómicos. Como resultado de ello, presenta las clasificaciones de los participantes en niveles establecidos por el valor y discute algunas implicaciones educativas de la investigación.

La présente recherche a eu pour objectif de construire et de valider une échelle de valeurs socio-morales qui a mesuré la présence et le mode d'adhésion aux valeurs de justice, de respect, de solidarité et de coexistence démocratique chez les étudiants et les enseignants du primaire et du secondaire dans des établissements publics et privés de São Paulo (10.011 participants). La méthodologie a englobé l'élaboration de récits avec alternatives pour et contre-valeur à trois niveaux de la perspective sociale, l'application de questionnaires à cet échantillon de personnes et le traitement de données basé sur la Théorie des Réponses aux Items - TRI -, d'après le modèle pour items polytomiques. Comme résultats, nous présentons les classifications des participants en fonction de niveaux établis par la valeur et nous discutons les implications éducationnelles de la recherche.

The use of residues, in partial or total substitution of aggregates or binders in concrete, presents interesting possibilities for obtaining eco-efficient concretes. Research has investigated the use of glass residue in Portland cement composite, whether as an aggregate or a supplementary cementitious material. However, there is still no consensus on the influence of the chemical composition of glass on the behaviour of the composites in which it is used. This paper analyse the influence of this composition on the performance of cement composites produced with microparticles of colourless and amber glass. Pozzolanicity was assessed by direct (Modified Chapelle, electrical conductivity) and indirect test (chemical characterization, X-ray diffraction, thermogravimetric analysis, differential thermal analysis and Strength Activity Index testing. The results show that microparticles of both glass display pozzolanic activity, with no significant differences between them. This confirms the potential for the use of glass microparticles as a supplementary material in cement composites.

This study optimized and validated the liquid-liquid extraction technique with partition at low temperature (LLE-PLT) for identification and quantification of four pesticides (chlorpyrifos, λ-cyhalothrin, permethrin, bifenthrin) in water samples. Analyses were performed by HPLC-UV. The technique was efficient for pesticide recovery with extraction exceeding 86%. Chromatographic response was linear for the four compounds in the 10-45 µg L-1 range, with correlation coefficients greater than 0.99. Limits of detection and quantitation were less than 3.5 µg L-1 and equal to 10 µg L-1, respectively. The proposed method was applied to 29 water samples from the Jaíba Project in northern Minas Gerais.