Abstract This study aimed to evaluate the physical properties and antifungal activities of polymethyl methacrylate (PMMA) acrylic resins after the incorporation of chlorhexidine diacetate salt (CDA). Methodology: First, acrylic resin specimens were fabricated with Vipi Cor® and DuraLay® resins with and without the incorporation of 0.5%, 1.0% or 2.0% CDA. The residual monomer and CDA release were measured at intervals ranging from 2 hours to 28 days using ultraviolet spectrometry combined with high-performance liquid chromatography. The antifungal activity against C. albicans was evaluated with the agar diffusion method. Fourier transform infrared spectroscopy was used to analyze the degree of resin conversion. Finally, the water sorption values of the resins were also measured. Results: The incorporated CDA concentration significantly changed the rate of CDA release (p<0.0001); however, the brand of the material appeared to have no significant influence on drug release. Subsequently, the inhibition zones were compared between the tested groups and within the same brand, and only the comparisons between the CDA 2% and CDA 1% groups and between the CDA 1% and CDA 0.5% groups failed to yield significant differences. Regarding the degrees of conversion, the differences were not significant and were lower only in the CDA 2% groups. Water sorption was significantly increased at the 1.0% and 2.0% concentrations. Conclusions: We concluded that the incorporation of CDA into PMMA-based resins enabled the inhibition of C. albicans growth rate, did not alter the degrees of conversion of the tested resins and did not change the release of residual monomers.

OBJETIVO: verificar o desempenho de pacientes afásicos com distúrbios leves de compreensão em tarefas de figura-fundo e atenção seletiva para sons verbais em escuta de mensagem competitiva. MÉTODOS: foram incluídos neste estudo pacientes afásicos com distúrbio de compreensão leve, identificados através da aplicação do teste M1-Alpha. Além disso, deveriam apresentar audiometria tonal nas freqüências de 500Hz, 1KHZ, 2KHZ, compatível com a realização de testes auditivos centrais, medidas de imitância acústica normais e reflexos contralateral presentes bilateralmente. Foi utilizado o teste de identificação de sentenças PSI (Pediatric Speech Inteligibility) - versão em português. Inicialmente, todos os pacientes identificaram as frases que compõem o PSI à viva voz. Em seguida, foram submetidos ao Teste de Escuta Monótica e Dicótica. RESULTADOS: os pacientes apresentaram dificuldades de compreensão estatisticamente significantes na situação de mensagem competitiva ipsilateral, nas situações 0dB e -10dB, além de dificuldades de compreensão também na situação de mensagem competitiva contralateral MCC (- 40 dB). CONCLUSÕES: os pacientes afásicos apresentaram dificuldade na compreensão de estímulos verbais em tarefas de figura-fundo e atenção seletiva, perdendo parte da informação nestas condições. Os achados dessa pesquisa puderam contribuir de forma a elucidar em como a lesão cerebral e, conseqüentemente, o prejuízo de habilidades perceptuais auditivas pode interferir na compreensão de pacientes afásicos no dia-a-dia, em que várias mensagens concorrem de forma competitiva.

PURPOSE: to analyze the performance of aphasic patients with mild comprehension disorders in tasks of back-image and selective attention to verbal sounds in listening tasks with competitive message. METHODS: the patients were submitted to an audiological assessment; acoustic immitance measures and measurements of acoustic reflex. An evaluation of comprehension in a propitious listening situation was made using M1-Alpha test. After that, the individuals who were able to understand simple sentences and presented an oral comprehension compatible with the achievement of the dichotic and monotic listening tests, in the presence of a competitive message (PSI) were included in this research. RESULTS: when we compared performance of patients in the sonorous competition conditions, there was a significant difference between test situations with ipsilateral competitive message. We believe that patient’s difficulty evaluated in this study is related to the message in a sonorous competition situation, mainly in the ipsilateral competitive message situation. CONCLUSIONS: aphasic patients had difficulty in tasks of back-image and selective attention to verbal sounds with competitive message. These findings contribute to show how the brain lesion and consequently the auditory disorder can interfere in daily oral comprehension in aphasic patients.