Abstract Background Deep Brain Stimulation (DBS) is an established treatment option for refractory dystonia, but the improvement among the patients is variable. Objective To describe the outcomes of DBS of the subthalamic region (STN) in dystonic patients and to determine whether the volume of tissue activated (VTA) inside the STN or the structural connectivity between the area stimulated and different regions of the brain are associated with dystonia improvement. Methods The response to DBS was measured by the Burke-Fahn-Marsden Dystonia Rating Scale (BFM) before and 7 months after surgery in patients with generalized isolated dystonia of inherited/idiopathic etiology. The sum of the two overlapping STN volumes from both hemispheres was correlated with the change in BFM scores to assess whether the area stimulated inside the STN affects the clinical outcome. Structural connectivity estimates between the VTA (of each patient) and different brain regions were computed using a normative connectome taken from healthy subjects. Results Five patients were included. The baseline BFM motor and disability subscores were 78.30 ± 13.55 (62.00-98.00) and 20.60 ± 7.80 (13.00-32.00), respectively. Patients improved dystonic symptoms, though differently. No relationships were found between the VTA inside the STN and the BFM improvement after surgery (p = 0.463). However, the connectivity between the VTA and the cerebellum structurally correlated with dystonia improvement (p = 0.003). Conclusions These data suggest that the volume of the stimulated STN does not explain the variance in outcomes in dystonia. Still, the connectivity pattern between the region stimulated and the cerebellum is linked to outcomes of patients.

Resumo Antecedentes A estimulação cerebral profunda (ECP) é um tratamento estabelecido para distonias refratárias. Porém, a melhora dos pacientes é variável. Objetivo O objetivo do estudo foi descrever os desfechos da ECP da região do núcleo subtalâmico (NST) e determinar se o volume de tecido ativado (VTA) dentro do NST ou se a conectividade estrutural entre a área estimulada e diferentes regiões cerebrais estão associadas a melhora da distonia. Métodos A resposta da ECP em pacientes com distonia generalizada isolada de etiologia hereditária/idiopática foi mensurada pela escala de Burke-Fahr-Marsden Dystonia Rating Scale (BFM) antes e 7 meses após a cirurgia. A soma dos volumes do NST nos dois hemisférios foi correlacionada com a melhora nos escores do BFM para avaliar se a área estimulada dentro do NST afeta o desfecho clínico. A conectividade estrutural estimada entre o VTA de cada paciente e as diferentes regiões cerebrais foram computadas usando um conectoma normativo retirado de indivíduos saudáveis. Resultados Cinco pacientes com idade de 40,00 ± 7,30 anos foram incluídos. O BFM motor e de incapacidade basal eram de 78,30 ± 13,55 (62,00-98,00) e 20,60 ± 7,80 (13,00-32,00), respectivamente. Os pacientes melhoraram com a cirurgia, mas com variabilidade. Não houve relação entre o VTA dentro do NST e a melhora do BFM após a cirurgia (p = 0.463). Entretanto, a conectividade estrutural entre o VTA e o cerebelo correlacionaram com a melhora da distonia (p = 0.003). Conclusão Os dados sugerem que o VTA dentro do NST não explica a variabilidade do desfecho clínico na distonia. Porém, o padrão de conectividade entre a região estimulada e o cerebelo foi relacionada com o desfecho dos pacientes.

Resumo Introdução: O consumo dos produtos derivados do tabaco, do plantio ao consumo, são responsáveis por graves problemas de saúde, representando um ciclo de doenças, pobreza e mortes em todo o mundo. Esse grave problema de saúde pública levou o Brasil a desenvolver, a partir da década de 80, um conjunto de medidas de controle do tabaco, constituindo uma política com ações legislativas, econômicas, de comunicação e educativas, que tem como alicerce o Programa Nacional de Controle do Tabaco (PNCT). Objetivo Este artigo é um relato de experiência que parte de um estudo nacional desenvolvido entre 2020 e 2022, e descreve atuação através de visitas técnicas junto às coordenações de controle do tabagismo de cinco estados. Método Os estados foram selecionados mediante a critérios estabelecidos pela Ditab/INCA, que coordena a rede do Programa Estadual de Controle do Tabagismo (PECT) nos 26 estados e Distrito Federal. Desta forma, foi escolhido um estado de cada região: Tocantins (Norte), Paraíba (Nordeste), Goiás (Centro-Oeste), Rio de Janeiro (Sudeste) e Paraná (Sul). Resultados Foi desenvolvido um conjunto de práticas que possam potencializar, aprimorar e agregar ações técnicas, políticas, de comunicação, dentre outras, de modo a dar sustentabilidade ao Programa Estadual e de maneira mais ampla, o PNCT.

Abstract Introduction The consumption of tobacco products, from planting to consumption, is responsible for serious health problems, representing a cycle of diseases, poverty and deaths worldwide. This serious public health problem led Brazil to develop, from the 1980s onwards, a set of tobacco control measures, constituting a policy with legislative, economic, communication and educational actions, which has as its foundation the National Program for Control of Tobacco. Tobacco (PNCT). Objective This article is an experience report that is part of a national study carried out between 2020 and 2022, and describes actions through technical visits to tobacco control coordination offices in five states. Method The states were selected according to criteria established by Ditab/INCA, which coordinates the network of the State Program for Tobacco Control (PECT) in the 26 States and Federative Unit of the country. Thus, a State of each region was chosen: Tocantins (North), Paraíba (Northeast), Goiás (Midwest), Rio de Janeiro (Southeast) and Paraná (South). Results Practices were developed to enhance, improve and add technical, political, communication actions, among others, in order to give sustainability to the State Program and, more broadly, the PNCT.

Abstract Background Management delays imply worse outcomes in rheumatoid arthritis (RA) and, therefore, should be minimized. We evaluated changes in diagnostic and treatment delays regarding RA in the last decades in Brazil. Methods Adults fulfilling the ACR/EULAR (2010) criteria for RA were assessed. Delays in diagnosis and treatment, and the frequencies of early management initiation within thresholds (windows of opportunity) of 3, 6, and 12 months from symptoms onset were evaluated. The Mann–Kendall trend test, chi-squared tests with Cramer’s V effect sizes and analysis of variance were conducted. Results We included 1116 patients: 89.4% female, 56.8% white, mean (SD) age 57.1 (11.5) years. A downward trend was found in diagnostic (tau = - 0.677, p < 0.001) and treatment (tau = - 0.695, p < 0.001) delays from 1990 to 2015. The frequency of early management increased throughout the period, with ascending effect sizes across the 3-, 6-, and 12-month windows (V = 0.120, 0.200 and 0.261, respectively). Despite all improvements, even in recent years (2011–2015) the diagnostic and treatment delays still remained unacceptably high [median (IQR): 8 (4–12) and 11 (5–17) months, respectively], with only 17.2% of the patients treated within the shortest, 3-month window. Conclusion The delays in diagnosis and treatment of RA decreased during the last decades in Brazil. Improvements (effect sizes) were greater at eliminating extreme delays (≥ 12 months) than in attaining really short management windows (≤ 3 months). Very early treatment was still an unrealistic goal for most patients with RA.

Abstract Background Early rheumatoid arthritis (RA) offers an opportunity for better treatment outcomes. In real-life settings, grasping this opportunity might depend on access to specialized care. We evaluated the effects of early versus late assessment by the rheumatologist on the diagnosis, treatment initiation and long-term outcomes of RA under real-life conditions. Methods Adults meeting the ACR/EULAR (2010) or ARA (1987) criteria for RA were included. Structured interviews were conducted. The specialized assessment was deemed “early” when the rheumatologist was the first or second physician consulted after symptoms onset, and “late” when performed afterwards. Delays in RA diagnosis and treatment were inquired. Disease activity (DAS28-CRP) and physical function (HAQ-DI) were evaluated. Student's t, Mann-Whitney U, chi-squared and correlation tests, and multiple linear regression were performed. For sensitivity analysis, a propensity score-matched subsample of early- vs. late-assessed participants was derived based on logistic regression. The study received ethical approval; all participants signed informed consent. Results We included 1057 participants (89.4% female, 56.5% white); mean (SD) age: 56.9 (11.5) years; disease duration: 173.1 (114.5) months. Median (IQR) delays from symptoms onset to both RA diagnosis and initial treatment coincided: 12 (6–36) months, with no significant delay between diagnosis and treatment. Most participants (64.6%) first sought a general practitioner. Notwithstanding, 80.7% had the diagnosis established only by the rheumatologist. Only a minority (28.7%) attained early RA treatment (≤ 6 months of symptoms). Diagnostic and treatment delays were strongly correlated (rho 0.816; p < 0.001). The chances of missing early treatment more than doubled when the assessment by the rheumatologist was belated (OR 2.77; 95% CI: 1.93, 3.97). After long disease duration, late-assessed participants still presented lower chances of remission/low disease activity (OR 0.74; 95% CI: 0.55, 0.99), while the early-assessed ones showed better DAS28-CRP and HAQ-DI scores (difference in means [95% CI]: −0.25 [−0.46, −0.04] and − 0.196 [−0.306, −0.087] respectively). The results in the propensity-score matched subsample confirmed those observed in the original (whole) sample. Conclusions Early diagnosis and treatment initiation in patients with RA was critically dependent on early access to the rheumatologist; late specialized assessment was associated with worse long-term clinical outcomes.

SUMMARY OBJECTIVE: Sickle cell disease is the most frequent of the hereditary hemoglobinopathies and it presents multisystemic effects. A manifestation that is commonly found in sickle cell disease is upper airway obstruction, particularly adenotonsillar hypertrophy. This study aims to evaluate the peak nasal inspiratory flow measurements of children and adolescents with sickle cell disease. METHODS: This is a case-control study on children aged between 8 and 15 years who were diagnosed with sickle cell disease. Peak nasal inspiratory flow measurements were obtained from patients. RESULTS: A total of 279 patients were enrolled in this study, with 93 in the case group and 186 in the control group. The case group had an 82.83% chance of having lower peak nasal inspiratory flow values than the control group. In the case group, 75% of the peak nasal inspiratory flow values were in the lower standards, whereas in the control group, only 25% were in the lower standards. CONCLUSION: This study showed a high prevalence of reduced peak nasal inspiratory flow values in children with sickle cell disease and could certainly be incorporated into the day-to-day clinical evaluation of patients as a screening instrument.

Abstract Introduction The consumption of tobacco products, from planting to consumption, is responsible for serious health problems, representing a cycle of diseases, poverty and deaths worldwide. This serious public health problem led Brazil to develop, from the 1980s onwards, a set of tobacco control measures, constituting a policy with legislative, economic, communication and educational actions, which has as its foundation the National Program for Control of Tobacco. Tobacco (PNCT). Objective This article is an experience report that is part of a national study carried out between 2020 and 2022, and describes actions through technical visits to tobacco control coordination offices in five states. Method The states were selected according to criteria established by Ditab/INCA, which coordinates the network of the State Program for Tobacco Control (PECT) in the 26 States and Federative Unit of the country. Thus, a State of each region was chosen: Tocantins (North), Paraíba (Northeast), Goiás (Midwest), Rio de Janeiro (Southeast) and Paraná (South). Results Practices were developed to enhance, improve and add technical, political, communication actions, among others, in order to give sustainability to the State Program and, more broadly, the PNCT.

Resumo Introdução: O consumo dos produtos derivados do tabaco, do plantio ao consumo, são responsáveis por graves problemas de saúde, representando um ciclo de doenças, pobreza e mortes em todo o mundo. Esse grave problema de saúde pública levou o Brasil a desenvolver, a partir da década de 80, um conjunto de medidas de controle do tabaco, constituindo uma política com ações legislativas, econômicas, de comunicação e educativas, que tem como alicerce o Programa Nacional de Controle do Tabaco (PNCT). Objetivo Este artigo é um relato de experiência que parte de um estudo nacional desenvolvido entre 2020 e 2022, e descreve atuação através de visitas técnicas junto às coordenações de controle do tabagismo de cinco estados. Método Os estados foram selecionados mediante a critérios estabelecidos pela Ditab/INCA, que coordena a rede do Programa Estadual de Controle do Tabagismo (PECT) nos 26 estados e Distrito Federal. Desta forma, foi escolhido um estado de cada região: Tocantins (Norte), Paraíba (Nordeste), Goiás (Centro-Oeste), Rio de Janeiro (Sudeste) e Paraná (Sul). Resultados Foi desenvolvido um conjunto de práticas que possam potencializar, aprimorar e agregar ações técnicas, políticas, de comunicação, dentre outras, de modo a dar sustentabilidade ao Programa Estadual e de maneira mais ampla, o PNCT.

Abstract This study evaluated a method to determine the spatial geometry of root canal preparation (RCP) using navigation dynamics and a specific algorithm from a new CBCT software (e-Vol DX). CBCT scans of 168 root canals of mandibular molars were acquired before and after RCP, using nickel-titanium (NiTi) instruments (ProTaper Next, BioRace, Reciproc Blue, and WaveOne Gold). The spatial geometry of the root canals and the operative risk of disproportional wear of dentinal walls after RCP were evaluated using a new CBCT software. A 3-point scoring system was used after the measuring of cementum/dentin thickness before and after RCP in all root thirds. The root thirds were distributed into three parts of similar sizes, and the scores were categorized at three levels: 1. mild risk (1/3), 2. moderate risk (2/3), 3. severe risk (3/3). These levels were proposed according to the risk of creating disproportionate shapes, thin walls, or perforations. The data were analyzed statistically by Fischer’s exact test (α = 5%). There were no significant differences in operative risk among the NiTi engine-driven systems, for the distal or mesial walls of all the root canal thirds (p>0.05). The spatial geometry method to assess operative risk allows clinical planning for a predictable enlargement of the root canal in all root thirds. Based on using a map-reading strategy on root canals in CBCT scans, NiTi engine-driven instruments did not present an increased operative risk during RCPs.

Resumo Este estudo avaliou um método para determinar a geometria espacial do preparo do canal radicular (PCR) usando uma dinâmica de navegação e um algoritmo específico do software e-Vol DX. Imagens de tomografia computadorizada de feixe cônico (TCFC) de 168 molares inferiores foram adquiridas antes e depois do PCR, usando instrumentos de níquel-titânio (NiTi) (ProTaper Next, BioRace, Reciproc Blue e WaveOne Gold). A geometria espacial dos canais radiculares e o risco operatório de desgaste desproporcional das paredes dentinárias após o preparo foram avaliados usando o software de TCFC e-Vol DX. Um sistema de Score de 3 pontos foi usado após a mensuração da espessura cemento/dentina antes e depois do PCR, em toda extensão dos canais radiculares. Os terços radiculares foram distribuídos em três partes de tamanhos semelhantes, e os Scores foram categorizados em três níveis: 1. risco leve (1/3), 2. risco moderado (2/3), 3. risco severo (3/3). Esses níveis foram propostos de acordo com o risco de criar formas desproporcionais, paredes finas ou perfurações radiculares. Os dados foram analisados estatisticamente pelo teste exato de Fischer ((=5%). Não houve diferenças significativas no risco operatório entre os sistemas de NiTi acionados a motor, para as paredes distal ou mesial em todos os terços do canal radicular (p>0,05). O método de geometria espacial para avaliar o risco operatório permite o planejamento clínico para um alargamento previsível do canal radicular em todos os terços radiculares. Com base no uso de uma estratégia de navegação dinâmica de canais radiculares de molares inferiores analisados em imagens de TCFC, os instrumentos de NiTi acionados estudados não apresentaram um aumento do risco operatório durante o preparo dos canais radiculares.

Abstract BRS A705 is an early-maturing cultivar developed by Embrapa, recommended for irrigated cultivation. The plants have high tillering and moderate resistance to the main diseases. This cultivar has short stature, which confers a greater tolerance to lodging. It presents high yield and long and fine grains of excellent quality. A A70 earlymaturing early maturing Embrapa cultivation diseases stature lodging quality A7

Abstract SCSBRS126 Dueto is a late-maturing high yield performing cultivar released by Epagri/Embrapa/Udesc. It has high tillering capacity, but poor resistance to lodging, medium resistance to blast, with long, slender grains and good sensory/cooking traits, and it has lower sterility under cold stress at microsporogenesis/anthesis and under heat at anthesis. SCSBRS SCSBRS12 latematuring late maturing EpagriEmbrapaUdesc Epagri Embrapa Udesc Epagri/Embrapa/Udesc capacity lodging blast long sensorycooking sensory cooking traits microsporogenesisanthesis microsporogenesis anthesis SCSBRS1

ABSTRACT Background: The epidemic curve has been obtained based on the 7-day moving average of the events. Although it facilitates the visualization of discrete variables, it does not allow the calculation of the absolute variation rate. Recently, we demonstrated that the polynomial interpolation method can be used to accurately calculate the daily acceleration of cases and deaths due to COVID-19. This study aimed to measure the diversity of epidemic curves and understand the importance of socioeconomic variables in the acceleration, peak cases, and deaths due to COVID-19 in Brazilian states. Methods: Epidemiological data for COVID-19 from federative units in Brazil were obtained from the Ministry of Health’s website from February 25 to July 11, 2020. Socioeconomic data were obtained from the Instituto Brasileiro de Geografia e Estatística (https://www.ibge.gov.br/). Using the polynomial interpolation methods, daily cases, deaths and acceleration were calculated. Moreover, the correlation coefficient between the epidemic curve data and socioeconomic data was determined. Results: The combination of daily data and case acceleration determined that Brazilian states were in different stages of the epidemic. Maximum case acceleration, peak of cases, maximum death acceleration, and peak of deaths were associated with the Gini index of the gross domestic product of Brazilian states and population density but did not correlate with the per capita gross domestic product of Brazilian states. Conclusions: Brazilian states showed heterogeneous data curves. Population density and socioeconomic inequality were correlated with a more rapid exponential growth in new cases and deaths.

Resumo: Beija-flores são especializados no consumo de néctar e desempenham um papel importante em comunidades de plantas Neotropicais, agindo como organismos polinizadores. Apesar da importância dessa relação mutualística, estudos sobre a relação de plantas e beija-flores ainda são escassos no Cerrado. Neste estudo, objetivamos descrever a rede de interações entre beija-flores e plantas em campos rupestres e matas ripárias localizadas em áreas de altitude do Parque Nacional da Serra da Canastra. Estabelecemos dois transectos em cada fitofisionomia, os quais foram amostrados mensalmente durante quatro dias, de novembro de 2018 a outubro de 2019. Plantas em floração em cada transecto foram observadas em cada amostragem, e todos os beija-flores visitantes foram registrados. As redes de interação foram construídas utilizando o pacote bipartite do R, considerando cada fitofisionomia e agrupando os dados de ambos os ambientes. Destes três arranjos de rede, extraímos métricas complementares no nível de comunidade (modularidade, aninhamento e índice de especialização de rede) e no nível de espécies (índice de especialização da espécie e força da espécie na rede). Registramos 647 interações entre 10 espécies de beija-flores e 23 espécies de plantas. O beija-flor Colibri serrirostris foi o responsável pela maior parte das interações ave-planta observadas e a planta Qualea cordata foi a mais visitada. A rede geral foi significativamente modular com quatro módulos e apresentou considerável especialização e baixo aninhamento. A rede de interações no campo rupestre apresentou maior especialização, aninhamento e índice de modularidade quando comparada à mata ripária, enquanto as métricas deste ecossistema não foram diferentes da rede geral. Entretanto, as métricas no nível de espécies de beija-flores não apresentaram diferenças significativas entre as fitofisionomias. Este estudo corrobora alguns resultados de redes de beija-flores-plantas em outras áreas do domínio do Cerrado, mas também aponta idiossincrasias nas redes das fitofisionomias investigadas, especialmente os campos rupestres.

Abstract: Hummingbirds are specialized in consumption of nectar and play an important role in Neotropical plant communities acting as pollinator organisms. Despite the importance of this mutualistic interaction, studies about hummingbird-plant relationships remain scarce regarding the Cerrado domain (Brazilian savanna). In this study, we aimed to describe the interaction network between hummingbirds and plants in rupestrian fields and riparian forests located in altitudinal areas of the Serra da Canastra National Park. We established two transects in each phytophysiognomy, that were sampled monthly for four days, from November 2018 to October 2019. Flowering plants in each transect were observed each survey, and all the visiting hummingbirds were recorded. Networks were constructed using the R bipartite package, considering each phytophysiognomy type, and grouping data of both environments. From these three network arrangements, we extracted complementary metrics at the community level (modularity, nestedness, and network specialization index), and at the species level (species specialization index and species strength in the network). We recorded 647 interactions between 10 hummingbird species and 23 flowering plant species. The hummingbird Colibri serrirostris was responsible for most of observed bird-plant interactions and the plant Qualea cordata was the most visited. The general network was significantly modular, comprising four modules, and showed considerable high specialization and low nestedness. The interaction network in the rupestrian field showed a higher specialization, nestedness, and modularity index when compared to riparian forests, while the metrics of this ecosystem did not differ from those of the general network. However, the metrics at hummingbird species level did not differ significantly between phytophysiognomies. This study corroborated some findings about hummingbird-plant networks in other areas of the Cerrado domain, but also pointed idiosyncrasies in networks of the investigated phytophysiognomies, especially the rupestrian fields.

RESUMO A comunidade quilombola Mesquita possui uma identidade intimamente relacionada com a terra; todavia, atualmente, as relações entre saúde e saneamento apresentam-se de forma precarizada devido à expansão do agronegócio e do mercado imobiliário. O objetivo deste estudo foi identificar os aspectos de saúde e saneamento da comunidade quilombola Mesquita da Cidade Ocidental do estado de Goiás, Brasil. Esta revisão foi estruturada no método de um scoping review elaborado com a finalidade de síntese de evidências auxiliando no direcionamento de políticas públicas e na tomada de decisões práticas para o território. Os principais resultados encontrados nos aspectos de saúde foram a importância da Unidade Básica de Saúde, da agroecologia e das terapias alternativas. Já nos aspectos de saneamento foram o abastecimento de água e o tratamento/disposição de resíduos sólidos. Constata-se que o fortalecimento e a interdependência da saúde humana e ambiental, da cultura e da ancestralidade da história africana e o reconhecimento dos direitos territoriais potencializarão o cuidado coletivo com o suporte de diferentes atores sociais. É notório que o enfrentamento da escravidão no Brasil ainda existe no Quilombo Mesquita, pela invisibilidade e inassistência refletidas atualmente pelas ações governamentais.

ABSTRACT The Mesquita quilombola community has an identity closely related to land, however, nowadays, the relationship between health and sanitation is precarious due to the expansion of agribusiness and the real estate market. The aim of this study was to identify the health and sanitation aspects of the quilombo community of Mesquita of Cidade Ocidental, in the state of Goiás, Brazil. This review was structured using a scoping review method designed to synthesize evidence to help guide public policies and make practical decisions for the territory. The main results found in health aspects were the importance of the Basic Health Unit, of agroecology, and of alternative therapies. As for sanitation, they were water supply and treatment/disposal of solid waste. It is said that the strengthening and interdependence of human and environmental health, of the culture and ancestry of African history and recognition of territorial rights will enhance collective care with the support of different social actors. It is clear that the fight against slavery in Brazil still exists in the Mesquita quilombo, due to the invisibility and lack of assistance currently reflected by governmental actions.

RESUMO A comunidade quilombola Mesquita possui uma identidade intimamente relacionada com a terra; todavia, atualmente, as relações entre saúde e saneamento apresentam-se de forma precarizada devido à expansão do agronegócio e do mercado imobiliário. O objetivo deste estudo foi identificar os aspectos de saúde e saneamento da comunidade quilombola Mesquita da Cidade Ocidental do estado de Goiás, Brasil. Esta revisão foi estruturada no método de um scoping review elaborado com a finalidade de síntese de evidências auxiliando no direcionamento de políticas públicas e na tomada de decisões práticas para o território. Os principais resultados encontrados nos aspectos de saúde foram a importância da Unidade Básica de Saúde, da agroecologia e das terapias alternativas. Já nos aspectos de saneamento foram o abastecimento de água e o tratamento/disposição de resíduos sólidos. Constata-se que o fortalecimento e a interdependência da saúde humana e ambiental, da cultura e da ancestralidade da história africana e o reconhecimento dos direitos territoriais potencializarão o cuidado coletivo com o suporte de diferentes atores sociais. É notório que o enfrentamento da escravidão no Brasil ainda existe no Quilombo Mesquita, pela invisibilidade e inassistência refletidas atualmente pelas ações governamentais.

ABSTRACT The Mesquita quilombola community has an identity closely related to land, however, nowadays, the relationship between health and sanitation is precarious due to the expansion of agribusiness and the real estate market. The aim of this study was to identify the health and sanitation aspects of the quilombo community of Mesquita of Cidade Ocidental, in the state of Goiás, Brazil. This review was structured using a scoping review method designed to synthesize evidence to help guide public policies and make practical decisions for the territory. The main results found in health aspects were the importance of the Basic Health Unit, of agroecology, and of alternative therapies. As for sanitation, they were water supply and treatment/disposal of solid waste. It is said that the strengthening and interdependence of human and environmental health, of the culture and ancestry of African history and recognition of territorial rights will enhance collective care with the support of different social actors. It is clear that the fight against slavery in Brazil still exists in the Mesquita quilombo, due to the invisibility and lack of assistance currently reflected by governmental actions.