Abstract Objective To assess the association between two colposcopic indices, the Swede score and the 2011 International Federation of Cervical Pathology and Colposcopy (IFCPC) Nomenclature as well as to determine the efficacy of the Swede score with cutoffs of 7 and 8. Methods In the present cross-sectional pilot study, 34 women who had at least 1 colposcopy-directed biopsy due to abnormal cytology were enrolled. The colposcopic findings were scored by both the Swede score and the 2011 IFCPC Nomenclature and were compared with each other. The Kappa coefficient and the McNemar test were used. Accuracy, sensitivity, specificity, and positive and negative predictive values (NPV and PPV, respectively) were calculated, as well as the effectiveness with cutoffs of 7 and 8 in identifying cervical intraepithelial neoplasm (CIN) 2+ when using the Swede score. Results The correlation between the 2 colposcopic indices was 79.41%. The Kappa coefficient and the McNemar p-value were 0.55 and 0.37, respectively. The IFCPC Nomenclature had sensitivity, specificity, accuracy, PPV, and NPV of 85.71, 55.00, 67.64, 57.14, and 84.61%, respectively. The Swede score had sensitivity, specificity, accuracy, PPV, and NPV of 100, 63.15, 79.41, 68.18, and 100%, respectively. A Swede score cutoff of 7 for CIN 2+ detection had a specificity of 94.73%, while with a cutoff of 8 it increased to 100%. The sensitivity for both values was 60%. The PPV and NPV for cutoffs of 7 and 8 were 90 and 75 and 100 and 76%, respectively. Conclusion Although both colposcopic indices have good reproducibility, the Swede score showed greater accuracy, sensitivity, and specificity in identifying CIN 2 + , especially when using a cutoff of 8.

Resumo Objetivo Avaliar a associação entre dois índices colposcópicos, o escore Swede e a Nomenclatura International Federation of Cervical Pathology and Colposcopy (IFCPC, na sigla em inglês) 2011, assim como determinar a eficácia do escore Swede com os pontos de corte 7 e 8. Métodos Trata-se de um estudo transversal, com 34 mulheres incluídas, que realizaram colposcopia com biópsia dirigida devido a uma citologia anormal. Os achados colposcópicos foram categorizados pelo escore Swede e pela Nomenclatura IFCPC 2011 e comparados um com o outro. Foram avaliados o coeficiente Kappa e o teste de McNemar e foram calculados a acurácia, a sensibilidade, a especificidade e valores preditivos negativos e positivos (VPN e VPP, respectivamente) de cada índice, assim como a eficácia com os pontos de corte 7 e 8 do escore Swede para determinar as lesões de neoplasia intraepitelial cervical (NIC) 2 + . Resultados A concordância entre os 2 índices foi de 79,41% e o coeficiente Kappa e o valor-p do teste de McNemar foram 0.55 e 0.37, respectivamente. Pela Nomenclatura IFCPC 2011, obtivemos como sensibilidade, especificidade, acurácia, VPP e VPN, respectivamente: 85,71, 55,00, 67,64, 57,14 e 84,61%. Pelo escore Swede obtivemos como sensibilidade, especificidade, acurácia, VPP e VPN, respectivamente: 100, 63,15, 79,41, 68,18 e 100%. O uso do escore Swede para detecção das lesões NIC 2+ obteve como especificidade 94,73% com o valor de corte de 7, enquanto o valor de corte 8 obteve 100%. A sensibilidade para ambos os cortes foi de 60%. O VPP e o VPN com os cortes 7 e 8 foram, respectivamente: 90,00 e 75,00 e 100,00 e 76,00%. Conclusão Ambos os índices colposcópicos tiveram boa reprodutibilidade; no entanto, o escore Swede mostrou melhor acurácia, sensibilidade e especificidade em identificar as lesões NIC 2+ e o melhor ponto de corte para identificar as lesões NIC2+ foi com o valor 8.

Resumo Objetivo Avaliar o efeito da Terapia floral na evolução do trabalho de parto e na tríade dor-ansiedade-estresse das mulheres durante o nascimento. Métodos Estudo quase-experimental realizado no período de maio a julho de 2018 no centro-obstétrico de um hospital referência para a assistência ao nascimento de baixo risco na Região Sul do Brasil, com 60 participantes (30 no Grupo Controle e 30 no Grupo Floral). A intervenção consistiu na administração dos Florais de Bach durante o trabalho de parto combinados por compostos capazes de regatar o equilíbrio emocional em situações de dor, ansiedade e estresse com a adição de 99,75% de conhaque orgânico Francês à 30% para 0,25% da tintura mãe. O grupo placebo recebeu uma mistura combinada de água com adição de 99,75% de conhaque orgânico Francês à 30% para 0,25% da tintura mãe. Ambos foram acondicionados em frascos conta gotas de 30 ml de igual tamanho, formato e característica. Para análise foi utilizado o teste t a fim de comparar as variáveis estudadas antes e após a intervenção e entre os grupos. Resultados As variáveis analisadas como dilatação cervical, contrações uterinas, ocitocina, cortisol e tempo do trabalho de parto apresentaram diferenças significativas para o Grupo Floral quando comparado com o placebo. Conclusão A Terapia floral pode ser uma alternativa para a mulher durante o trabalho de parto por auxiliar na progressão do parto sem trazer prejuízos ao recém-nascido.

Abstract Objective To evaluate the effect of flower therapy on the evolution of labor and on the pain-anxiety-stress triad of women during birth. Methods Quasi-experimental study conducted from May to July 2018 in the obstetric center of a reference hospital for low-risk birth care in southern Brazil with 60 participants (30 in the control group and 30 in the floral group). The intervention consisted of administering Bach Flower Remedies during labor combined with compounds capable of restoring emotional balance in situations of pain, anxiety and stress with the addition of 99.75% organic French brandy at 30% to 0.25% of the mother tincture. The placebo group received a combined water mix with added 99.75% organic French brandy at 30% to 0.25% of the mother tincture. Both were put in 30 ml dropper bottles of the same size, shape and characteristic. In the analysis, the t test was used to compare the variables studied before and after the intervention, and between groups. Results Variables analyzed such as cervical dilation, uterine contractions, oxytocin, cortisol and duration of labor showed significant differences for the floral group compared to placebo. Conclusion Flower therapy can be an alternative for women during labor, as it helps in the progression of labor without harming the newborn.

Resumen Objetivo Analizar el efecto de la terapia floral en la evolución del trabajo de parto y en la tríada dolor-ansiedad-estrés de mujeres durante el nacimiento. Métodos Estudio cuasi experimental realizado en el período de mayo a julio de 2018 en el centro obstétrico de un hospital de referencia en la atención al nacimiento de bajo riesgo en la región sur de Brasil, con 60 participantes (30 en el grupo de control y 30 en el grupo floral). La intervención consistió en la administración de Flores de Bach durante el trabajo de parto combinadas con compuestos capaces de rescatar el equilibrio emocional en situaciones de dolor, ansiedad y estrés con la adición de 99,75 % de coñac orgánico francés al 30 % en 0,25 % de tintura madre. El grupo placebo recibió una mezcla combinada de agua con la adición de 99,75 % de coñac orgánico francés al 30 % en 0,25 % de tintura madre. Ambas fueron colocadas en frascos con cuentagotas de 30 ml de igual tamaño, formato y características. Para el análisis se utilizó el test-T a fin de comparar las variables estudiadas antes y después de la intervención y entre los grupos. Resultados Las variables analizadas, como dilatación cervical, contracciones uterinas, oxitocina, cortisol y tiempo de trabajo de parto presentaron diferencias significativas en el Grupo Floral en comparación con el de placebo. Conclusión La terapia floral puede ser una alternativa para la mujer durante el trabajo de parto porque ayuda a la evolución del parto sin perjuicios para el recién nacido.

RESUMO Objetivo: Analisar as evidências científicas disponíveis na literatura sobre os elementos que viabilizam a técnica de debriefing oral orientado por instrutor na simulação clínica em enfermagem. Métodos: Revisão integrativa da literatura realizada nas fontes de informação: PubMed®, Scopus, Web of Science, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Cumulative Index to Nursing and Allied Health Literature (CINAHL) e Educational Resources Information Centre (ERIC). Resultados: Identificaram-se 284 estudos, e 5 compuseram a amostra. Quatro elementos constituem o debriefing oral: características do instrutor; formato da discussão, estrutura do debriefing; e tempo. O principal benefício foi desenvolver habilidades cognitivas e psicomotoras; e o desafio, estabelecer treinamento aos instrutores. Os estudos apresentaram alta qualidade metodológica. Considerações finais: O aprofundamento científico quanto aos elementos, benefícios e desafios do debriefing oral possibilita sua execução e confere qualidade ao processo para enfermagem.

ABSTRACT Objective: To analyze available scientific evidence in literature pertaining to the elements that make the instructor-led oral debriefing technique in clinical nursing simulation feasible. Methods: An Integrative literature review along the following information sources: PubMed®, Scopus, Web of Science, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) [Latin American and Caribbean Health Sciences Literature], Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Educational Resources Information Centre (ERIC). Results: 284 studies were identified, and 5 composed the sample. Four elements constitute oral debriefing: characteristics of the instructor; discussion format, debriefing structure; and time frame. The main benefit was to develop cognitive and psychomotor skills; and the challenge was to establish training for instructors. The studies showed high methodological quality. Final Considerations: The scientific deepening as to the elements, benefits, and challenges of oral debriefing enables its execution and offers quality to the nursing process.

RESUMEN Objetivo: Analizar las evidencias científicas disponibles en la literatura sobre los elementos que hacen viable la técnica de debriefing oral orientado por instructor en la simulación clínica en enfermería. Métodos: Revisión integrativa de la literatura realizada en las fuentes de información: PubMed®, Scopus, Web of Science, Literatura Latinoamericana y del Caribe en Ciencias de Salud (LILACS), Cumulative Index to Nursing and Allied Health Literature (CINAHL) y Educational Resources Information Centre (ERIC). Resultados: Se identificaron 284 estudios, y 5 compusieron la muestra. Cuatro elementos constituyen el debriefing oral: características del instructor; formato de la discusión, estructura del debriefing; y tiempo. El principal beneficio ha sido desarrollar habilidades cognitivas y psicomotrices; y el desafío, establecer entrenamiento a los instructores. Los estudios presentaron alta calidad metodológica. Consideraciones finales: La profundización científica cuanto a los elementos, beneficios y desafíos del debriefing oral posibilita su ejecución y confiere calidad al proceso para enfermería.

Abstract Background: Rheumatoid arthritis (RA) is a common autoimmune systemic inflammatory disease. In addition to joint involvement, RA patients frequently have other comorbidities, such as cardiovascular diseases. Drugs used for RA treatment may increase or decrease the risk of a cardiovascular event. This study aims to analyze cardiovascular risk comorbidities in patients with RA and the correlation with the use of anti-rheumatic drugs. Methods: Cross-sectional study conducted based on the real-life rheumatoid arthritis study database - REAL, a prospective observational cohort study. Associations between the use of anti-rheumatic drugs and the presence of comorbidities were represented by their prevalence ratio and evaluated using the Chi-square or Fisher’s Exact tests. Results: We assessed 1116 patients, 89.4% women, mean age of 55.15 years and predominance of seropositive disease. 63.3% had some cardiovascular comorbidity, predominantly hypertension (49.9%). The use of glucocorticoids was observed in 47.4% of patients and there was a significant tendency of lower use of these drugs in the presence of dyslipidemia (PR: 0.790; p = 0.007). We observed that the presence of cardiovascular comorbidities was associated with higher use of bDMARDs (PR:1.147; p = 0.003). Conclusions: The presence of cardiovascular risk comorbidities was confirmed to be higher in RA patients. Different treatment strategies using less glucocorticoids in the presence of dyslipidemia and more common use of bDMARDs in patients with cardiovascular comorbidities suggest that rheumatologists are aware of the potential influence of the DMARDs in the risk of cardiovascular event. Reinforcing these results, we highlight the need for a better baseline assessment to guide the choice of anti-rheumatic drugs in RA patients who have comorbidities.

Abstract The National Policy of Protection and Civil Defense (Law 12.608/2012) assigns to municipalities many competences in prevention, mitigation, preparation, response and recovery aimed at civil protection and defense. The reality of Brazilian municipalities, especially small size ones, has been living with the lack of financial and human resources to accomplish these responsibilities. This paper investigates the potential of public inter-municipal consortia to reduce vulnerabilities, especially institutional, technical and political, in the context of disaster risk. Several experiences of public consortia in Brazil were investigated through a reflexive study, considering the potential and the challenges for their constitution and maintenance. The political, financial and operational capacity of consortia could support more specialized activities, such as mapping disaster risk areas and contingency plans. In opposition, the consortium is not able to solve all the difficulties faced by the municipalities, and it is necessary to overcome political-party barriers and indifference of local management. After overcoming these challenges, cooperation shows considerable potential to strengthen municipal capacities for reducing disaster risks.

Resumo A Política Nacional de Proteção e Defesa Civil, instituída pela Lei nº 12.608/2012, atribui aos municípios diversas competências em prevenção, mitigação, preparação, resposta e recuperação voltadas à proteção e defesa civil. A realidade dos municípios brasileiros, em especial aqueles de pequeno porte, tem sido a convivência com a escassez de recursos financeiros e humanos para o cumprimento de tais responsabilidades. Este artigo investiga o potencial dos consórcios públicos intermunicipais para a redução das vulnerabilidades, em especial institucional, técnica e política, no contexto de risco de desastres. Por meio de um estudo reflexivo, diversas experiências de consórcios públicos no Brasil foram investigadas, considerando as potencialidades e os desafios enfrentados em sua constituição e manutenção. A capacidade política, financeira e operacional dos consórcios pode viabilizar as atribuições de caráter mais especializado, a exemplo dos mapeamentos de áreas de risco de desastres e dos planos de contingência. Por outro lado, o consórcio por si só não é capaz de resolver todas as dificuldades enfrentadas pelos municípios, sendo necessário ultrapassar entraves político-partidários e desinteresse da gestão local. Vencidos estes desafios, a cooperação mostra-se com grande potencial para fortalecer as capacidades municipais voltadas para a redução do risco de desastres.

Abstract A new juice market, consisting of mixtures of fruits, is expanding in the beverage segment, in order to increase even more the nutritional and sensory characteristics. In addition, in the preparation of juices, the option exists to replace water with coconut water. The aim of this study was to develop and optimize mixed juices based on coconut water and berries (strawberry, blackberry, and red raspberry), through the mixture design, desirability function, and response surface methodology. Mixed juices were evaluated by rheological, physical, physicochemical, sensory, and nutritional characteristics. The treatments produced with strawberry (50% or 100%) were preferred among the tasters, and the juices elaborated using blackberry contributed to higher viscosity, antioxidant activity, phenolic compounds, and total anthocyanins. According to optimization, the mixed juices should contain 50-60% strawberry, 40% blackberry, and 0-10% raspberry. Thus, the mixed juices produced from these fruits have better characteristics than the juice of only one fruit type.

RESUMEN Objetivo: identificar los factores asociados a las hospitalizaciones por sífilis congénita en recién nacidos desde las características de la asistencia prenatal. Materiales y método: estudio cuantitativo tipo caso control, realizado por medio de la aplicación de encuesta a 65 puérperas con sus bebés hospitalizados de julio a noviembre del 2017. Se analizaron los datos mediante regresión logística, de acuerdo con el plan propuesto en el enfoque jerárquico. Resultados: el 20 % de las hospitalizaciones se dio por sífilis (casos) y el 80 % por otras causas (control). Las variables riesgo de vulnerabilidad (p = 0,036), historia previa de infección sexualmente transmisible (p = 0,006), uso del contraceptivo oral(p = 0,011) y paridad(p = 0,043) fueron estadísticamente significativas. Adicionalmente, se asociaron a la ocurrencia del desfecho la ausencia del compañero en la cita (p = 0,028), la no realización de la prueba rápida para detección de sífilis (p = 0,035) y la actividad educativa para el compañero (p = 0,033), además de las variables del neonato: bajo peso al nacer (p = 0,025), no encontrarse en lactancia exclusiva (p = 0,036) y no haber tenido contacto piel con piel (p = 0,043). Conclusiones: la sífilis congénita presenta diversos factores de riesgo para su ocurrencia. Fue posible observar que las iniquidades asistenciales en la atención durante las citas de prenatal refleten directamente en la ocurrencia de este agravo.

ABSTRACT Objective: To identify the factors associated with hospitalizations due to congenital syphilis in neonates, based on the characteristics of prenatal care. Materials and method: A quantitative case-control study, conducted by applying a questionnaire to 65 puerperal women with their babies hospitalized from July to November 2017. The data were analyzed using logistic regression, according to the plan proposed in the hierarchical approach. Results: 20% of the hospitalizations were due to syphilis (cases) and 80% to other causes (control). The vulnerability risk (p = 0.036), previous history of sexually transmitted infection (p = 0,006), use of oral contraceptives (p = 0.011) and parity (p = 0.043) variables were statistically significant. The absence of the partner during the consultation (p = 0.028), failure to perform a rapid test for syphilis (p = 0.035) and educational activity for the partner (p = 0.033) were also associated with the occurrence of the outcome, in addition to the variables of the newborn: low birth weight(p = 0.025), not being on exclusive breastfeeding (p = 0.036) and not having had skin-to-skin contact(p = 0.043). Conclusions: Congenital syphilis has several risk factors for its occurrence. It was possible to observe that the assistance inequalities existing in care during the prenatal consultations directly reflect on the occurrence of this condition.

RESUMO Objetivo: identificar os fatores associados às internações por sífilis congênita em neonatos, a partir das características da assistência pré-natal. Materiais e método: estudo quantitativo tipo caso controle, realizado por meio da aplicação de questionário a 65 puérperas com seus bebês internados de julho a novembro de 2017. Os dados foram analisados mediante regressão logística, segundo o plano proposto na abordagem hierárquica. Resultados: 20 % das internações foram por sífilis (casos) e 80 % por outras causas (controle). As variáveis risco de vulnerabilidade (p = 0,036), história prévia de infecção sexualmente transmissível(p = 0,006), uso do contraceptivo oral (p = 0,011) e paridade (p = 0,043) foram estatisticamente significativas. Também foram associadas à ocorrência do desfecho a ausência do parceiro durante a consulta (p = 0,028), a não realização de teste rápido para a sífilis (p = 0,035) e a atividade educativa para o parceiro (p = 0,033), além das variáveis do neonato: baixo peso ao nascer (p = 0,025), não estar em aleitamento materno exclusivo (p = 0,036) e não ter tido contato pele a pele (p = 0,043). Conclusões: a sífilis congênita apresenta diversos fatores de risco para a sua ocorrência. Foi possível observar que as iniquidades assistenciais existentes no atendimento durante as consultas de pré-natal refletem diretamente na ocorrência desse agravo.

RESUMO Objetivou-se avaliar os efeitos da aplicação exógena de ácido salicílico como indutor de resistência ao ácaro-rajado e à traça em genótipos de tomateiro. Para isso, realizaram-se bioensaios com três genótipos comerciais (‘Redenção’, ‘Giuliana’ e ‘Alambra’) e um silvestre (Solanum habrochaites var. hirsutum acesso PI-127826). Determinou-se a distância média percorrida pelo ácaro-rajado e o número de ovos depositados sobre os folíolos dos genótipos. Com relação ao bioensaio da traça-do-tomateiro, foram avaliados o número de ovos e lagartas na superfície do folíolo e a porcentagem de área foliar consumida pelas lagartas por meio de digitalização dos folíolos. Além disso, avaliou-se a severidade do ataque na planta utilizando uma escala de notas referente a danos, tipos de lesões e folíolos atacados. A aplicação de ácido salicílico induziu resistência nos genótipos comerciais para ambas as pragas, diminuindo a oviposição do ácaro e da traça do tomateiro. Os ácaros percorreram menor distância nos folíolos dos genótipos que receberam tratamento com ácido salicílico nas concentrações intermediarias, indicando efeito benéfico da substância na indução de resistência. A severidade do ataque da traça do tomateiro, também foi coibida quando aplicadas doses intermediárias de ácido salicílico. Entretanto, observou-se resistência superior do acesso PI-127826 em relação aos demais genótipos. Isso indica que a resistência de PI-127826 se deve à defesa constitutiva, enquanto que nos genótipos comerciais as defesas são dependentes, em parte, de respostas de indução mediadas pelo ácido salicílico. Dessa forma, pode se inferir que o ácido salicílico é eficiente como indutor de resistência ao ácaro rajado e à traça-do-tomateiro, sendo bastante promissor dentro de um manejo integrado de pragas em cultivos comerciais de tomateiro.

ABSTRACT This study was performed to evaluate the effect of exogenous application of salicylic acid as a resistance inducer to two-spotted spider mite and tomato pinworm on tomato genotypes. Bioassays were carried out in three commercial genotypes (‘Redenção’, ‘Giuliana’, and ‘Alambra’) and one wild genotype (Solanum habrochaites var. hirsutum, accession PI-127826). Average distance travelled by the two-spotted spider mite and number of eggs deposited over the leaflets of the genotypes were investigated. Concerning pinworm bioassay, number of eggs, leafminers on leaflet surface and percentage of leaf area consumed by leafminers were evaluated using a scanner. Furthermore, severity of attack to plants was evaluated by score scale for damages, types of lesions and attacked leaflets. Salicylic acid application induced resistance in the commercial genotypes against both pests, reducing the two-spotted spider mite and pinworm oviposition. The spider mites travelled shorter distance on leaflets of genotypes treated with salicylic acid at intermediate concentrations, indicating a positive effect of substance as inducing resistance. Attack severity by pinworm was also reduced when intermediate doses of salicylic acid were applied. Also, higher resistance was observed on accession PI-127826 as compared to other genotypes. The obtained results indicate that the resistance of PI-127826 was due to constitutive defense, whereas on commercial genotypes defense was dependent on responses mediated by salicylic acid. Hence, salicylic acid treatment, as resistance inducer, seems to be efficient against two-spotted spider mite and pinworm, being a promising tool within an integrated pest management on tomato plants.

Abstract Recently, many researches have become available in order to value agroindustrial waste and by-products through processes that exploit these wastes and transform them into new value-added products. Thus, this study aimed to assess the chemical composition (proximate analysis, mineral profile, pectic substances, carbohydrates), fatty acid profile, and bioactive compounds of two major exotic fruit wastes (seeds), marolo and soursop, largely found in one of the richest Brazilian biomes, the Savannah. Soursop and marolo seeds showed significant fat (295.1 and 311.3 g kg-1 d.b., respectively), protein (149.9 and 188.7 g kg-1 d.b., respectively), and fiber (426.7 and 351.1 g kg-1 d.b., respectively) contents. Marolo seeds were found to be the richest in phenolic compounds (32043.1 mg GAE kg-1 d.b.) and also presented the highest DPPH• scavenging activity (91.25%). The major phenolic compound found in marolo and soursop seeds was rutin. Among the fatty acids found in both seeds, the ones with unsaturated chains were predominant, such as oleic acid (48.54% for marolo, and 40.35% for soursop seeds). The seeds analyzed were found to be sources of Cu and Mg. Marolo and soursop seeds were found to be a good source of nutritional compounds and an alternative to obtain compounds of interest to be used in the development of food produce, pharmaceutical, and cosmetic products.

Abstract Objective: To investigate quality of life and its correlations with psychosocial factors (anxiety, depression and low self-esteem) in men who underwent prostatectomy. Methods: A descriptive, correlational study with 85 men who underwent radical prostatectomy at least three months and at most five years prior to the survey. The instruments used were the European Organization for Research and Treatment of Cancer- QLQ C30, the European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; the Rosenberg Self-Esteem Scale and the Hospital Anxiety and Depression Scale. Results: Participants showed impairment of quality of life associated with impairment of sexual function and presence of urinary symptoms. There was a correlation between the psychosocial aspects and some quality of life assessment scales, mainly the functional and symptom scales. Conclusion: It was shown that radical prostatectomy causes impairment in the quality of life of men, requiring care from health professionals to minimize the effects of the most common complications. Educational interventions and multi-professional support based on a better understanding of the physical and psychosocial implications are recommended to help improve the quality of life of men after radical prostatectomy.

Resumen Objetivo: Investigar la calidad de vida relacionada a la salud y correlación con factores psicosociales (ansiedad, depresión y autoestima) en hombres prostatectomizados. Métodos: Estudio descriptivo correlacional realizado con 85 hombres sometidos a prostatectomía radical hace al menos tres meses y máximo cinco años. Se utilizó el European Organization for Research and Treatment of Cancer- QLQ C30 y European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; Escala de Autoestima de Rosenberg y Hospital Anxiety and Depression Scale. Resultados: Los participantes mostraron su calidad de vida comprometida con relación al detrimento de la función sexual y presencia de síntomas urinarios. Hubo correlación entre los aspectos psicosociales y algunas escalas de evaluación de calidad de vida, principalmente las escalas funcionales y de síntomas. Conclusión: Quedó en evidencia que la prostatectomía radical perjudica la calidad de vida de los hombres y demanda asistencia de los profesionales de la salud para minimizar los efectos de las complicaciones más comunes. Se recomienda la implementación de intervenciones educativas y de apoyo multiprofesional para una mejor comprensión de las consecuencias físicas y psicosociales para ayudar a mejorar la calidad de vida de los hombres después de la prostatectomía radical.

Resumo Objetivo: Investigar a qualidade de vida relacionada à saúde e correlações com fatores psicossociais (ansiedade, depressão e autoestima) em homens prostatectomizados. Métodos: Estudo descritivo correlacional realizado com 85 homens submetidos a prostatectomia radical há no mínimo três meses e no máximo cinco anos. Foram utilizados o European Organization for Research and Treatment of Cancer- QLQ C30 e European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; Escala de Autoestima de Rosenberg e Hospital Anxiety and Depression Scale. Resultados: Os participantes mostraram comprometimento da qualidade de vida no que se refere a prejuízos da função sexual e presença de sintomas urinários. Houve correlação entre os aspectos psicossociais e algumas escalas de avaliação da qualidade de vida, principalmente as escalas funcionais e de sintomas. Conclusão: Evidenciou-se que a prostatectomia radical causa prejuízo na qualidade de vida dos homens, demandando assistência dos profissionais de saúde para minimizar os efeitos das complicações mais comuns. Recomenda-se a implementação de intervenções educativas e apoio multiprofissional pautados em melhor compreensão das implicações físicas e psicossociais para ajudar a melhorar a qualidade de vida dos homens após a prostatectomia radical.

Resumo Objetivo: Investigar a qualidade de vida relacionada à saúde e correlações com fatores psicossociais (ansiedade, depressão e autoestima) em homens prostatectomizados. Métodos: Estudo descritivo correlacional realizado com 85 homens submetidos a prostatectomia radical há no mínimo três meses e no máximo cinco anos. Foram utilizados o European Organization for Research and Treatment of Cancer- QLQ C30 e European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; Escala de Autoestima de Rosenberg e Hospital Anxiety and Depression Scale. Resultados: Os participantes mostraram comprometimento da qualidade de vida no que se refere a prejuízos da função sexual e presença de sintomas urinários. Houve correlação entre os aspectos psicossociais e algumas escalas de avaliação da qualidade de vida, principalmente as escalas funcionais e de sintomas. Conclusão: Evidenciou-se que a prostatectomia radical causa prejuízo na qualidade de vida dos homens, demandando assistência dos profissionais de saúde para minimizar os efeitos das complicações mais comuns. Recomenda-se a implementação de intervenções educativas e apoio multiprofissional pautados em melhor compreensão das implicações físicas e psicossociais para ajudar a melhorar a qualidade de vida dos homens após a prostatectomia radical.

Abstract Objective: To investigate quality of life and its correlations with psychosocial factors (anxiety, depression and low self-esteem) in men who underwent prostatectomy. Methods: A descriptive, correlational study with 85 men who underwent radical prostatectomy at least three months and at most five years prior to the survey. The instruments used were the European Organization for Research and Treatment of Cancer- QLQ C30, the European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; the Rosenberg Self-Esteem Scale and the Hospital Anxiety and Depression Scale. Results: Participants showed impairment of quality of life associated with impairment of sexual function and presence of urinary symptoms. There was a correlation between the psychosocial aspects and some quality of life assessment scales, mainly the functional and symptom scales. Conclusion: It was shown that radical prostatectomy causes impairment in the quality of life of men, requiring care from health professionals to minimize the effects of the most common complications. Educational interventions and multi-professional support based on a better understanding of the physical and psychosocial implications are recommended to help improve the quality of life of men after radical prostatectomy.

Resumen Objetivo: Investigar la calidad de vida relacionada a la salud y correlación con factores psicosociales (ansiedad, depresión y autoestima) en hombres prostatectomizados. Métodos: Estudio descriptivo correlacional realizado con 85 hombres sometidos a prostatectomía radical hace al menos tres meses y máximo cinco años. Se utilizó el European Organization for Research and Treatment of Cancer- QLQ C30 y European Organization for Research and Treatment of Cancer “Prostate Cancer” 25 items - EORTC QLQ-PR25; Escala de Autoestima de Rosenberg y Hospital Anxiety and Depression Scale. Resultados: Los participantes mostraron su calidad de vida comprometida con relación al detrimento de la función sexual y presencia de síntomas urinarios. Hubo correlación entre los aspectos psicosociales y algunas escalas de evaluación de calidad de vida, principalmente las escalas funcionales y de síntomas. Conclusión: Quedó en evidencia que la prostatectomía radical perjudica la calidad de vida de los hombres y demanda asistencia de los profesionales de la salud para minimizar los efectos de las complicaciones más comunes. Se recomienda la implementación de intervenciones educativas y de apoyo multiprofesional para una mejor comprensión de las consecuencias físicas y psicosociales para ayudar a mejorar la calidad de vida de los hombres después de la prostatectomía radical.

Abstract Pequi, murici and sweet passionfruit are typical fruits from Brazilian Cerrado, which stand out for their sensory attributes such as color, flavor and aroma, in addition to their high nutritional value. Their seeds are by-products from the industrial processing of juices, pulps, jellies, and others, and have great exploitation potential due to their high oil content and the presence of bioactive compounds. The present work aimed to evaluate the chemical composition of pequi almonds, and of murici and sweet passionfruit seeds, and also to quantify the total phenolic compounds, carotenoids, anthocyanins and antioxidant activity by the scavenging activity of •DPPH method. Concerning the chemical composition, pequi almonds presented the highest concentration of lipids (50%), followed by sweet passionfruit (30%) and murici seeds (15%). The almonds from pequi fruit showed the greatest content of protein (33.3%) followed by sweet passionfruit seeds (15%), which presented the highest amount of fiber (41.3%). Murici seeds exhibited the highest content of carbohydrates (46.4%). Pequi almonds had the greatest content of the following minerals, potassium, magnesium, sulfur, manganese, zinc, copper, iron, and sodium, and anthocyanins (14.4 mg CYG/100 g d.b.). Sweet passionfruit seeds presented the greatest amount of calcium, and also had the highest carotenoid content (9 mg/100 g d.b.). Murici seeds showed the highest potential for bioactive compounds, with 404 mg GAE/100 g d.b. and 81% of scavenging activity for the •DPPH. The results demonstrated that the studied seeds have the potential to be sources for new product development, such as oil.

RESUMO A abelha irapuá Trigona spinipes (Hymenoptera: Apidae) é uma importante praga do cultivo do copo-de-leite, Zantedeschia aethiopica (L.), pois causa danos nas inflorescências, principalmente na espádice. O objetivo foi identificar a embalagem mais eficiente para o ensacamento de inflorescências de copo-de-leite, visando a proteção contra o ataque da abelha irapuá e a manutenção da qualidade pós-colheita. O experimento foi conduzido em cultivo de copo-de-leite plantado em solo sob 50% de sombreamento. Os tratamentos consistiram do ensacamento das inflorescências com: 1) papel kraft; 2) TNT branco (comercialmente denominado tecido não tecido); 3) plástico transparente; 4) plástico transparente microperfurado; 5) testemunha (sem ensacamento). O delineamento experimental foi inteiramente casualizado contendo 25 repetições e uma inflorescência de copo-de-leite por parcela. As inflorescências receberam os tratamentos quando as mesmas apresentavam-se com a cor definitiva, mas ainda com a espata totalmente fechada. Sete dias após o ensacamento, as inflorescências foram colhidas e avaliadas quanto aos danos ocasionados pelos insetos no campo e quanto às características pós-colheita. As avaliações da qualidade pós-colheita das inflorescências foram realizadas por 12 dias, observando a expansão da espata em comprimento e largura, peso da haste e a qualidade visual expressa pelo número de dias que permaneceram em cada classe. O ensacamento das inflorescências de copo-de-leite foi eficiente no controle da abelha irapuá, independentemente do tipo de embalagem utilizada, pois nessas condições nenhuma inflorescência apresentou danos. Já na testemunha foram observadas 84% das inflorescências danificadas. Observaram-se diferenças nas características pós-colheita, sendo que as inflorescências permaneceram por maior período em fase de abertura da espata, que é caracterizada pelas medidas de comprimento e largura das mesmas, quando embaladas. Dentre as embalagens, destacou-se o TNT que possibilitou maior comprimento da espata ao 6° dia de avaliação, maior largura da mesma ao 7° dia de avaliação e menor perda de massa fresca ao final do experimento (8%). Já a testemunha teve murcha precoce caracterizada pela redução das medidas da espata à partir do primeiro dia de avaliação e perda de 11% da massa fresca. Conclui-se que o TNT mostrou-se como uma embalagem eficiente para proteção contra o ataque da abelha irapuá sem comprometer a qualidade das inflorescências na pós-colheita.

ABSTRACT Stingless bee Trigona spinipes (Hymenoptera: Apidae) is an important pest of calla lily, Zantedeschia aethiopica (L.), damaging flowers, especially the spadix. The aim was to identify the most efficient packaging for bagging calla lily inflorescences, aiming to protect against the attack of stingless bee and to maintain postharvest quality. The experiment was carried out in a calla lily plantation cultivated in soil under 50% shading screen. Treatments consisted in bagging calla lily flowers with: 1) brown kraft paper bag, 2) non-woven fabric (NWF) bag; 3) transparent plastic bag, 4) transparent micro-perforated plastic bag and 5) control (without bagging). The experimental design was completely randomized with 25 replicates and one inflorescence per plot. Inflorescences received treatments when they presented definitive color, but still with completely closed spathe. Seven days after bagging, inflorescences were collected and evaluated for damages caused by insects in the field and the postharvest characteristics. Postharvest quality evaluations of inflorescences were performed for 12 days, observing expansion of the spathe in length and width, stem weight and visual quality expressed by the number of days that remained in each class. The bagging of calla lily inflorescences was efficient in the control of stingless bee, regardless of packaging used, because under these conditions, no inflorescence presented damage. In control, 84% of damaged inflorescences were observed. Differences in postharvest characteristics were observed and inflorescences remained for longer periods in the process of spathe opening, which is characterized by the measurement of their length and width, when packed. Among packages, NWF allowed longer spathe length at the 6th day of evaluation, larger width at 7th day of evaluation and less fresh mass loss at the end of the experiment (8%). In control, reduction of spathe measurements from the first day of evaluation and loss of 11% of fresh mass were observed. It was concluded that NWF is an efficient packaging to protect calla lily against the attack of stingless bee without compromising the postharvest quality of inflorescences.

Resumo Esse relato apresenta um caso de neoplasia trofoblástica gestacional após mola hidatiforme parcial ocorrida na tuba uterina. Trata-se de uma associação rara, cuja incidência estima-se de 1 em cada 20.000 a 100.000 gestações, havendomenos de 300 casos apresentados na literatura ocidental. O tema é importante porque apresenta critérios diagnósticos atuais para essa ocorrência incomum, que vinha sendo diagnosticada equivocadamente, não apenas sob o ponto de vista morfológico, como também imunohistoquímico. Da mesma forma, alerta o obstetra para a ocorrência da gravidez molar ectópica, que tende a evoluir com rotura tubária mais frequentemente do que os casos de gravidez ectópica não molar. Por fim, a evolução do caso para neoplasia trofoblástica gestacional impõe às pacientes com gravidez ectópica molar a necessidade de seguimento pós-molar tão rigoroso quanto nos casos de mola hidatiforme intrauterina, ainda que o tratamento quimioterápico determine elevadas taxas de cura.

Abstract This report presents the case of a patient with gestational trophoblastic neoplasia after a partial hydatidiform mole formed in the Fallopian tube. Ectopic molar pregnancy is a rare condition, with an estimated incidence of 1 in every 20,000 to 100,000 pregnancies; less than 300 cases of it have been reported in the Western literature. The present report is important because it presents current diagnostic criteria for this rare condition, which has been incorrectly diagnosed in the past, not only morphologically but also immunohistochemically. It also draws the attention of obstetricians to the occurrence of ectopic molar pregnancy, which tends to progress to Fallopian tube rupture more often than in cases of ectopic non-molar pregnancy. Progression to gestational trophoblastic neoplasia ensures that patients with ectopic molar pregnancy must undergo postmolar monitoring, which must be just as thorough as that of patients with intrauterine hydatidiform moles, even if chemotherapy results in high cure rates.

OBJECTIVE: The aim of this study was to assess the relationship between the degree of unilateral spatial neglect during the acute phase of stroke and long-term functional independence. METHODS: This was a prospective study of right ischemic stroke patients in which the independent variable was the degree of spatial neglect and the outcome that was measured was functional independence. The potential confounding factors included sex, age, stroke severity, topography of the lesion, risk factors, glycemia and the treatment received. Unilateral spatial neglect was measured using the line cancellation test, the star cancellation test and the line bisection test within 48 hours of the onset of symptoms. Functional independence was measured using the modified Rankin and Barthel scales at 90 days after discharge. The relationship between unilateral spatial neglect and functional independence was analyzed using multiple logistic regression that was corrected for confounding factors. RESULTS: We studied 60 patients with a median age of 68 (34-89) years, 52% of whom were male and 74% of whom were Caucasian. The risk for moderate to severe disability increased with increasing star cancellation test scores (OR=1.14 [1.03-1.26], p=0.01) corrected for the stroke severity, which was a confounding factor that had a statistically positive association with disability (OR=1.63 [1.13-2.65], p=0.01). The best chance of functional independence decreased with increasing star cancellation test scores (OR=0.86 [0.78-0.96], p=0.006) corrected for the stroke severity, which was a confounding factor that had a statistically negative association with independence (OR=0.66 [0.48-0.92], p=0.017). CONCLUSION: The severity of unilateral spatial neglect in acute stroke worsens the degree of long-term disability and functional independence.