ABSTRACT The knowledge of the entomological fauna in productive systems is important for the agroecological management since beneficial insects are a key resource for pest management in horticultural systems. Scientific information on the biodiversity present in a given area is essential as well as the ecological function and/or feeding habits of the insects. In Alto Valle de Río Negro and Neuquén, horticultural production systems can be described as highly dependent on chemical inputs for pest management and fertilization. The aim of this study is to carry out an inventory of the biodiversity of some families of Hemiptera, Coleoptera (Curculionidae) and Hymenoptera present in peri-urban and rural farms located in Neuquén and Río Negro, respectively. Insects were collected through pitfall and sweeping net on tomato and pepper crops and the surrounding non-cultivated areas. Idiosystatus Berg (Auchenorrhyncha) was cited for the first time from Argentina. Species cited for the first time from Neuquén: Hemiptera: Auchenorrhyncha: Acanalonia chloris (Berg), Syncharina punctatissima (Signoret), Amplicephalus dubius Linnavuori, Exitianus obscurinervis (Stál), Agalliana ensigera Oman and Bergallia signata (Stál); Hemiptera: Heteroptera: Harmostes (Harmostes) prolixus Stál and Atrachelus (Atrachelus) cinereus (Fabricius); Coleoptera: Curculionidae: Hypurus bertrandi (Perris), Naupactus leucoloma Boheman, Otiorhynchus rugosostriatus (Goeze) and Sitona discoideus Gyllenhal and Hymenoptera: Xylocopa (Neoxylocopa) augusti Lepeletier and Pseudagapostemon (Neagapostemon) slngularis Jorgensen. Species cited for the first time from Río Negro: Hemiptera: Auchenorrhyncha: Amplicephalus dubius Linnavuori, Amplicephalus marginellanus Linnavuori, Circulifer tenellus (Baker) and Xerophloea viridis (Fabricius); Hemiptera: Heteroptera: Tupiocoriscucurbitaceus (Spinola), Atrachelus (Atrachelus) cinereus (Fabricius), Dichelops furcatus (Fabricius) and Harmostes (Harmostes) prolixus Stál; Coleptera: Curculionidae: Naupactus xanthographus (Germar) and Hymenoptera: Diadasia pereyrae (Holmberg) and Dialictus autranellus (Vachal).

RESUMEN El conocimiento de la fauna entomológica presente en los sistemas productivos es importante para el manejo agroecológico ya que los insectos beneficiosos son un recurso clave para el manejo de plagas en los sistemas hortícolas. Es esencial contar con información científica sobre la biodiversidad presente en un área determinada y la función ecológica y/o los hábitos alimenticios de los insectos. En el Alto Valle de Río Negro y Neuquén, los sistemas de producción hortícola pueden describirse como altamente dependientes de los insumos químicos para el manejo de plagas y fertilización. El objetivo de este estudio es realizar un inventario de la biodiversidad de algunas familias de Hemiptera, Coleoptera (Curculionidae) e Hymenoptera presentes en las chacras periurbanas y rurales ubicadas en Neuquén y Río Negro, respectivamente. Los insectos fueron recolectados a través de trampas de caída y red entomológica en cultivos de tomate y pimiento, y áreas circundantes no cultivadas. Idiosystatus Berg (Auchenorrhyncha) fue citado por primera vez en Argentina. Especies citadas por primera vez en Neuquén: Hemiptera: Auchenorrhyncha: Acanalonia chloris (Berg), Syncharina punctatissima (Signoret), Amplicephalus dubius Linnavuori, Exitianus obscurinervis (Stál), Agalliana ensigera Oman y Bergallia signata (Stál); Hemiptera: Heteroptera: Harmostes (Harmostes) prolixus Stál y Atrachelus (Atrachelus) cinereus (Fabricius); Coleoptera: (Curculionidae): Hypurus bertrandi (Perris), Naupactus leucoloma Boheman, Otiorhynchus rugosostriatus (Goeze) y Sitona discoideus Gyllenhal e Hymenoptera: Xylocopa (Neoxylocopa) augusti Lepeletier and Pseudagapostemon (Neagapostemon) singularis Jorgensen. Especies citadas por primera vez en Río Negro: Hemiptera:Auchenorrhyncha:Amplicephalus dubius Linnavuori, Amplicephalus marginellanus Linnavuori, Circulifer tenellus (Baker) y Xerophloea viridis (Fabricius); Hemiptera: Heteroptera: Tupiocoriscucurbitaceus (Spinola), Atrachelus (Atrachelus) cinereus (Fabricius), Dichelops furcatus (Fabricius) y Harmostes (Harmostes) prolixus Stál; Coleóptera: Curculionidae: Naupactus xanthographus (Germar) e Hymenoptera: Diadasia pereyrae (Holmberg) y Dialictus autranellus (Vachal).

Defeitos na incorporação de N-glicanos nas proteínas humanas ocasionam um grupo de doenças multissistêmicas denominadas coletivamente distúrbios congênitos de glicosilação (DCG). Os DCG manifestam-se na infância com sintomas neurológicos que incluem principalmente atraso psicomotor, ataxia, hipotonia e episódios de acidente vascular cerebral. Várias proteínas do sistema hemostático somente tornam-se biologicamente ativas após a glicosilação. O objetivo deste estudo foi avaliar os anticoagulantes naturais (proteína S livre, proteína C e antitrombina) e os fatores da coagulação (VIII, IX e XI) em pacientes com DCG tipo I. Foram avaliados 11 pacientes com diagnóstico positivo para DCG tipo I (três do gênero masculino e oito do gênero feminino), idade média de 5,6 anos; e oito pacientes com diagnóstico negativo para DCG(quatro do gênero masculino e quatro do gênero feminino), idade média de 4,5 anos (grupo-controle). O diagnóstico de DCG tipo I foi realizado pela identificação do padrão de hipoglicosilação da transferrina plasmática. Na avaliação dos anticoagulantes naturais pode-se observar redução dos valores de PS livre e PC e uma redução marcante de AT, quando comparados com o grupo controle. Em relação aos fatores de coagulação não houve diferença significativa para os fatores VIII e IX e houve redução marcante do fator XI. Os resultados do presente estudo sugerem que a deficiência combinada de anticoagulantes naturais é responsável pelo estado pró-trombótico observado em pacientes com DCG. Sugerimos também que a análise dos parâmetros hemostáticos seja realizada para pacientes com DCG quando apresentarem sintomas clínicos de alteração do sistema hemostático e antes de procedimentos invasivos.

Defects in the biosynthesis of N-linked human protein glycosylation leads to a group of multisystem disorders collectively called congenital disorders of glycosylation (CDG). CDG present in infancy with neurologic symptoms that include psychomotor retardation, ataxia, hypotonia and stroke-like episodes. Many haemostatic system proteins only present biological activity after glycosylation. The aim of this study was to evaluate coagulation inhibitors (free protein S, protein C and antithrombin) and coagulation factors (VIII, IX and XI) in CDG type I patients. Eleven patients with CDG type I (three males and eight females) with a mean age of 5.6 years old, and eight patients without CDG (four males and four females) with a mean age of 4.5 years old (control group) were evaluated. The diagnoses of CDG type I were confirmed by isoelectric focusing of serum transferrin. When coagulation inhibitors were evaluated, decreased activity of free protein S and protein C, and a pronounced reduction of antithrombin were observed compared to the control group. There was no significant difference for coagulation factors VIII and IX but a markedly decrease in factor XI. The present results suggest that a combined deficiency of coagulation inhibitors is responsible for the pro-thrombotic state observed in CDG patients. We recommend that a haemostatic analysis should be performed in CDG patients with clinical haemostatic manifestations before invasive procedures are performed.

The deformation of the partially solidified strand during near net shape continuous casting of thin slabs is only one example of a technologically important process where a mushy zone is mechanically altered in order to achieve improved grain structures and homogeneity. However, the phenomena occurring during plastic deformation of a solidifying mush are poorly understood, have not been observed directly, and have not been modeled in detail. A mathematical model that predicts the temperature and solid fraction profiles, liquid concentration evolution, and solid phase displacement during the deformation of a solidifying mush is presented. This model is derived considering a two-dimensional case, the volume averaging method, the enthalpy technique, and a coordinate transformation to avoid a changing mesh in a numerical solution. The numerical results are found to match the experimental behavior of metallic alloys during solidification with or without deformation.