Pesquisa | SciELO

In juice and pulp extraction, about 10% of fruit waste is generated, which often ends up in landfills that can cause environmental damage, serve as food for insects and rodents, and cause health problems for humans. In this work, micronized guava waste was used as a filler in vulcanized compounds in natural rubber. Mechanical properties such as hardness, tensile strength, tear resistance, and abrasion resistance were evaluated, as well as thermal properties such as thermogravimetric analysis, in addition to scanning electron microscopy, X-ray fluorescence, elemental analysis, and infrared spectroscopy. According to the results of the mechanical properties tests, the addition of up to 20 phr of the filler tends to improve the tensile strength of the composites, resulting in an increase in the density of cross-links obtained through the Flory-Rehner method. The thermal behavior analyzed by TGA and FTIR spectra were not affected by the incorporation of fillers.

https://doi.org/10.1590/1980-5373-mr-2022-0515

Comparative evaluation of three laparoscopic cholecystectomy techniques in rabbit’s model
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Wittmaack, Monica Carolina Nery

; Conceição, Maria Eduarda Bastos Andrade Moutinho

; Vera, María Camila Maldonado

; Faccini, Rachel Inamassu

; Sembenelli, Guilherme

; Montanhim, Gabriel Luiz

; Menezes, Mareliza Possa de

; Rocha, Fabiana Del Lama

; Aires, Luiz Paulo Nogueira

; Moraes, Paola Castro

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e383523

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: The aim of this randomized study was to compare the complications and perioperative outcome of three different techniques of laparoscopic cholecystectomy (LC). Changes in the liver function test after LC techniques were investigated. Also, we compared the degree of postoperative adhesions and histopathological changes of the liver bed. Methods: Thirty rabbits were divided into three groups: group A) Fundus-first technique by Hook dissecting instrument and Roeder Slipknot applied for cystic duct (CD) ligation; group B) conventional technique by Maryland dissecting forceps and electrothermal bipolar vessel sealing (EBVS) for CD seal; group C) conventional technique by EBVS for gallbladder (GB) dissection and CD seal. Results: Group A presented a longer GB dissection time than groups B and C. GB perforation and bleeding from tissues adjacent to GB were similar among tested groups. Gamma-glutamyl transferase and alkaline phosphatase levels increased (p ≤ 0.05) on day 3 postoperatively in group A. By the 15th postoperative day, the enzymes returned to the preoperative values. Transient elevation of hepatic transaminases occurred after LC in all groups. Group A had a higher adherence score than groups B and C and was associated with the least predictable technique. Conclusions: LC can be performed using different techniques, although the use of EBVS is highly recommended.

https://doi.org/10.1590/acb383523

Neurophysics: Understanding brain activity with modeling complex systems mathematics Neurophysics
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Scorza, Fulvio A.

; Fiorini, Ana C.

; Rodrigues, Antônio M.

; Scorza, Carla A.

; Vilallonga, Gabriel D.

; Moret, Marcelo A.

; Rocha Filho, Tarcísio M.

; Finsterer, Josef

; Almeida, Antônio-Carlos G. de

Clinics

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2023, Volume 78 elocation 100158

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.clinsp.2022.100158

[SciELO Preprints] - Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
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Marin-Neto, José Antonio Rassi Jr., Anis Moraes Oliveira, Gláucia M. Lemos Correia, Luís Claudio Novaes Ramos Jr., Alberto Hasslocher-Moreno, Alejandro Marcel Luquetti Ostermayer, Alejandro Sousa, Andréa Silvestre de Amato Vincenzo de Paola, Angelo Sobral de Sousa, Antonio Carlos Pinho Ribeiro, Antonio Luiz Correia Filho, Dalmo Moraes de Souza, Dilma do Socorro Cunha-Neto, Edecio J. A. Ramires, Felix Bacal, Fernando Pereira Nunes, Maria do Carmo Martinelli Filho, Martino Ibrahim Scanavacca, Maurício Magalhães Saraiva, Roberto Alves de Oliveira Júnior, Wilson M. Lorga-Filho, Adalberto de Jesus Benevides de Almeida Guimarães, Adriana Lopes Latado Braga, Adriana Sarmento de Oliveira, Adriana V. L. Sarabanda, Alvaro Yecê das Neves Pinto, Ana Assis Lopes do Carmo, André Schmidt, André Costa, Andréa Rodrigues da Ianni, Barbara Maria Markman Filho, Brivaldo Eduardo Rochitte, Carlos Thé Macedo, Carolina Mady, Charles Chevillard, Christophe Bittencourt das Virgens, Cláudio Marcelo Nery de Castro, Cleudson De Paoli de Carvalho Britto, Constança Felícia Pisani, Cristiano do Carmo Rassi, Daniela C. Sobral Filho, Dario Rodrigues Almeida, Dirceu A. Bocchi, Edimar T. Mesquita, Evandro de Souza Nogueira Sardinha Mendes, Fernanda Pereira, Francisca Tatiana Sperandio da Silva, Gilberto Marcelo de Lima Peixoto, Giselle Glotz de Lima, Gustavo H. Veloso, Henrique Turin Moreira, Henrique Bellotti Lopes, Hugo Masciarelli Francisco Pinto, Ibraim Pinto Dias, João Carlos Bemfica, João Marcos Silva-Nunes, João Paulo Soares Barreto-Filho, José Augusto Kerr Saraiva, José Francisco Lannes-Vieira, Joseli Menezes Oliveira, Joselina Luzia V. Armaganijan, Luciana Martins, Luiz Cláudio C. Sangenis, Luiz Henrique Barbosa, Marco Paulo Almeida-Santos, Marcos Antônio Simões, Marcos Vinicius Shikanai-Yasuda, Maria Aparecida Vieira Moreira, Maria da Consolação Higuchi, Maria de Lourdes Costa Monteiro, Maria Rita de Cássia Felix Mediano, Mauro Felippe Maia Lima, Mayara T. Oliveira, Maykon Moreira Dias Romano , Minna Nitz, Nadjar de Tarso Jorge Medeiros, Paulo Vieira Alves, Renato Alkmim Teixeira, Ricardo Coury Pedrosa, Roberto Aras, Roque Morais Torres, Rosália dos Santos Povoa, Rui Manoel Rassi, Sérgio Gabriel Salles Xavier, Sérgio Marinho Martins Alves , Silvia B. N. Tavares, Suelene Lima Palmeira, Swamy da Silva Junior, Telêmaco Luiz da Rocha Rodrigues, Thiago Madrini Junior, Vagner Maia da Costa , Veruska Dutra, Walderez

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Data de publicação: 2022-10-11

Resumo: En Pt

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.nbsp; Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities. nbsp; Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.nbsp; The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.nbsp; The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.nbsp; nbsp;nbsp; Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.

Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.nbsp;nbsp;nbsp; Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.nbsp;

https://doi.org/10.1590/SciELOPreprints.4820

Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives
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Pacheco, Paulo A. F.

; Gonzaga, Daniel T.

; Cirne-Santos, Cláudio C.

; Barros, Caroline S.

; Gomes, Max W. L.

; Gomes, Rafaela S. P.

; Gonçalves, Mariana C.

; Ferreira, Vitor F.

; Rabelo, Vitor W.

; Abreu, Paula A.

; Faria, Robson X.

; Resende, Gabriel O. de

; Rocha, David R. da

; Paixão, Izabel C. N. P.

; Silva, Fernando C. da

Journal of the Brazilian Chemical Society

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Jun 2022, Volume 33 Nº 6 Páginas 556 - 569

Resumo: En | Texto: En | PDF: En

Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, there is no licensed vaccine or specific pharmacological treatment. Therefore, there is an increasing urgency in developing new antiviral drugs capable of specifically inhibiting viral replication. In the present work, we report the synthesis and antiviral activity evaluation of nineteen naphthoquinone derivatives, containing a sulfonamide or sulfonate group. Cell viability assays indicated a low toxic potential for all tested compounds and inhibitory assays against CHIKV identified five compounds with potent activity. The compounds were also evaluated for their virucidal potential, and the results demonstrated that compound 11a exhibited a virucidal effect higher than 70% in the treatment with 20 µM. Furthermore, in silico studies were performed to predict the antiviral drug targets.

https://doi.org/10.21577/0103-5053.20220010

Notes on the fecundity of the caridean shrimp Cuapetes americanus (Kingsley, 1878) in two preserved areas in São Paulo State: Laje de Santos and Vitória Island
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Moraes, Isabela Ribeiro Rocha de

; Trevisan, Marcia Rafaela Ramos

; Rodrigues, Gabriel Fellipe Barros

; Silva, Alexandre Ribeiro da

; Castilho, Antonio Leão

Nauplius

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2022, Volume 30 elocation e2022036

Resumo: En | Texto: En | PDF: En

Abstract In the Atlantic Ocean, the shrimp Cuapetes americanus (Kingsley, 1878) is well distributed. This species has been studied regarding its taxonomic status, distribution records, and some biological and reproductive traits. However, its fecundity and reproductive aspects have never been evaluated in Brazilian waters before. SCUBA (Self Contained Underwater Breathing Apparatus) diving and Artificial Refuge Substrate were used to sample C. americanus specimens quarterly in a sheltered location in the Marine State Parks of Laje de Santos and Vitória Island for a year (2015-2016). A total of 45 animals (carapace length 1.35-4.54 mm) were sampled: 6 females; 18 ovigerous females; 3 juveniles; and 17 males. The major axis references were employed to analyze the relationship between the second pleura (SPL) and the carapace length (CL). The fecundity was 87.05 ± 80.50 eggs and it was similar to other populations connected to it, and it was exclusively associated favorably with CL. Despite being a small and inconspicuous species, C. americanus is a caridean shrimp species that has evolved to thrive and breed on continental islands. The importance of the creation and revision of management plans for no-take marine areas on the Brazilian coast is supported when many kinds of information about the ecology and biology of the species are available, such as caridean shrimps, which can be present as a link between trophic levels of the aquatic food web.

https://doi.org/10.1590/2358-2936e2022036

A Reliable and Cost-Effective Method for Determination of Endocrine-Disrupting Compounds in Coastal Waters, Suspended Particulate Matter, and Sediments by Ultrafast Liquid Chromatography Coupled to Photodiode Array and Fluorescence Detectors
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Souza, Gabriel C. de

; Fahning, Cristiane S

; Hatje, Vanessa

; Rocha, Gisele O. da

Journal of the Brazilian Chemical Society

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Dez 2021, Volume 32 Nº 12 Páginas 2160 - 2173

Resumo: En | Texto: En | PDF: En

Analytical methods for determining 14 endocrine-disrupting compounds (EDCs) in coastal waters, suspended particles, and sediment samples were successfully performed by ultrafast liquid chromatography with photodiode array and fluorescence detections (UFLC-PDA-FLD). Solid phase extraction (SPE) and ultrasound-assisted extraction (USE) were used for sample preparation. Two chromatographic methods have been developed. An isocratic separation method was used to separate bisphenol A (BPA) and steroids and another gradient elution method to separate phthalates and alkylphenols. The detection by fluorescence was used for alkylphenols, BPA, and steroids and photodiode array (PDA) for phthalates. Limits of detection (LOD) ranged from 0.41 (4-tert-octylphenol (4tOP)) to 63 ng L-1 (dibutylphthalate (DBP)), 0.41 (4tOP) to 63.2 ng g-1 dried weight (dw) coastal waters, and solid samples (suspended particulate matter (SPM) and sediment samples), respectively. Recoveries ranged from 52 (diethylphthalate (DEP)) to 116% (DBP) for water, from 54 (DEP) to 108% (estrone (E1)) for SPM, and from 62 (4-n-nonylphenol (4nNP)) to 117% (4-n-octylphenol (4nOP)) for sediment samples. Finally, with the minimization of reagents and energy, the proposed methods were applied to samples collected from Todos os Santos Bay (BTS), Bahia, Northeastern Brazil.

https://doi.org/10.21577/0103-5053.20210108

Resultados perinatales en la mujer joven con cáncer de mama y embarazo
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Arteaga-Gómez, Ana C.

; Vázquez-Castellanos, Gabriel

; Sepúlveda-Rivera, Cintia María

; Rocha-Zavaleta, Leticia

; Reyes-Muñoz, Enrique

Gaceta médica de México

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Ago 2021, Volume 157 Nº 4 Páginas 431 - 436

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Introduction: Breast cancer associated with pregnancy is defined as a malignant neoplasm of the breast that is diagnosed during pregnancy, breastfeeding or one year after delivery. Objective: To analyze perinatal outcomes in a series of young patients with breast cancer and pregnancy in a tertiary care hospital. Methods: Retrospective, analytical study of 26 women younger than 40 years of age with breast cancer who resolved their pregnancy at the National Institute of Perinatology between 2013 and 2018. Clinical-pathological characteristics, perinatal outcomes and family planning methods were studied. Percentages and central tendency measures were obtained, and comparisons were made with the chi-square test or Fisher's exact tests. Results: Association of breast cancer with pregnancy was observed in 0.26 % of all births; mean age of presentation was 34 years, 38.4 % of cases had cancer at advanced clinical stages and 57.1 % of the women were treated with modified radical mastectomy; no trend towards higher perinatal complications was observed. Conclusions: Breast cancer associated with pregnancy implies an oncological challenge and does not appear to be a risk factor for adverse perinatal outcomes.

Resumen Introducción: El cáncer de mama asociado a embarazo se define como la neoplasia maligna de mama que se diagnostica durante el embarazo, la lactancia o un año después del parto. Objetivo: Analizar los resultados perinatales en una serie de pacientes jóvenes con cáncer de mama y embarazo en un hospital de tercer nivel. Métodos: Estudio analítico retrospectivo de 26 mujeres menores de 40 años con cáncer de mama que resolvieron su embarazo en el Instituto Nacional de Perinatología entre 2013 y 2018. Se estudiaron las características clínico-patológicas, resultados perinatales y métodos de planificación familiar. Se obtuvieron porcentajes y medidas de tendencia central y se realizaron comparaciones con pruebas de chi cuadrada o exacta de Fisher. Resultados: La asociación de cáncer de mama y embarazo se observó en 0.26 % de todos los nacimientos, la edad media de presentación fue de 34 años, 38.4 % de los casos cursaba con cáncer en estadio clínico avanzado y 57.1 % de las mujeres fueron tratadas con mastectomía radical modificada; no se apreció tendencia a mayores complicaciones perinatales. Conclusiones: El cáncer de mama asociado a embarazo implica un reto oncológico y no parece ser un factor de riesgo para desenlaces perinatales adversos.

https://doi.org/10.24875/gmm.20000871 48 downloads

Mitogenome of Coprophanaeus ensifer and phylogenetic analysis of the Scarabaeidae family (Coleoptera)
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Mello, Catarine Aragone de Albuquerque

; Amorim, Igor Costa

; Silva, Alexandre Freitas da

; Medeiros, Giuliene Rocha de

; Wallau, Gabriel Luz

; Moura, Rita de Cássia de

Genetics and Molecular Biology

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2021, Volume 44 Nº 3 elocation e20200417

Resumo: En | Texto: En | PDF: En

Abstract Several studies about the phylogenetic relationships of the Scarabaeinae subfamily (Coleoptera: Scarabaeidae) have been performed, but some phylogenetic uncertainties persist including the relationship and monophyly of different tribes and some genera. The aim of this study was to characterize the mitogenome of Coprophanaeus ensifer in order to establish its position within the Scarabaeidae family and to contribute to the resolution of some phylogenetic uncertainties. The mitogenome was sequenced on the Illumina HiSeq 4000, assembled using the Mitobim software and annotated in MITOS WebServer. The phylogenetic trees were reconstructed by Bayesian inference. The C. ensifer mitogenome is a molecule of 14,964 bp that contains the number and organization of the genes similar to those of most Coleoptera species. Phylogenetic reconstruction suggests monophyly of the tribe Phanaeini and supports the hypothesis that Coprini is a sister group of Phanaeini. The results also revealed the position of the tribe Oniticellini which is grouped with Onthophagini and Onitini. The geographic distribution of these species that form the most ancestral clade suggests with Scarabaeinae originated in Africa.

https://doi.org/10.1590/1678-4685-gmb-2020-0417 4 downloads

10.

New species of the Corumbataia cuestae group (Siluriformes: Loricariidae) from the Rio Tocantins basin, with comments on its phylogenetic relationships
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Thimotheo, Mateus Giovanni Rocha

; Benine, Ricardo Cardoso

; Oliveira, Claudio

; Silva, Gabriel de Souza da Costa e

Neotropical Ichthyology

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2020, Volume 18 Nº 4 elocation e200060

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Uma nova espécie de Corumbataiaé descrita para o Rio Maranhão, na bacia do Rio Tocantins na região central do Brasil. A nova espécie é diagnosticada dos demais congêneres pela presença de uma pequena área nua na ponta do focinho; por possuir o abdômen coberto por pequenas placas formando um escudo que alcança as placas laterais mid-ventrais; perfil anterior da cabeça arredondado em vista dorsal; lábio inferior não alcançando a linha transversal da cintura peitoral; e presença de 28 ou 29 vértebras. Altos valores de divergência genética também suportam a validade dessa nova espécie. Nossa análise filogenética encontrou um subclado derivado em Corumbataia, aqui denominado grupo Corumbataia cuestae, composto pela nova espécie mais C. cuestae, C. tocantinensis, C. britskii, C. liliai e C. lucianoi. Esse grupo é definido por possuir uma crista conspícua de odontódeos hipertrofiados na cabeça; ausência de nadadeira adiposa ou série única de placas na posição da nadadeira adiposa; anastomose dos canais sensoriais infraorbital e ótico sobre o pterótico-supracleitro. Aqui, nós também restringimos a distribuição de C. tocantinensisà bacia do Rio Araguaia.

Abstract A new species of Corumbataia is described from Rio Maranhão, Rio Tocantins basin, central Brazil. The new species is distinguished from all congeners by the presence of a small, naked area on snout tip; by having the abdomen covered with small platelets forming a shield which reaches the lateral mid-ventral plates; by the anterior profile of the head rounded in dorsal view; by the lower lip not reaching the transversal line of the pectoral girdle; and by the presence of 28 or 29 vertebrae. High genetic divergence in mitochondrial cytochrome c oxidase subunit I (COI) further supports the validity of this new species. Our phylogenetic analysis shows a derived subclade in Corumbataia, herein named as the Corumbataia cuestae group, composed of the new species plus C. cuestae, C. tocantinensis, C. britskii, C. liliai, and C. lucianoi. This group is defined by having a conspicuous crest of hypertrophied odontodes on head; absence of the adipose fin or a single series of platelets at adipose-fin position; and anastomosis of the infraorbital and otic sensory canals over the pterotic-supracleithrum. Here we also restrict the distribution of C. tocantinensis to the Rio Araguaia basin.

https://doi.org/10.1590/1982-0224-2020-0060 961 downloads

11.

Clinical-pathological aspects of oral lymphoepithelial cyst: case report
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Rocha, Lourival C. O. N.

; Silva, Gabriel G.

; Xerez, Mariana C.

; Barros, Caio César S.

; Pinheiro, Juliana C.

; Pereira, Laudenice L.

; Costa, Antônio L. L.

Jornal Brasileiro de Patologia e Medicina Laboratorial

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2020, Volume 56 elocation e1932020

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO O cisto linfoepitelial oral (CLEO) é uma lesão incomum, cuja patogênese ainda é pouco elucidada. O objetivo deste estudo é relatar um caso de CLEO. Paciente do sexo feminino, leucoderma, 62 anos, apresentou aumento de volume nodular assintomático de consistência amolecida, em borda lateral da língua. Sob a hipótese clínica de hiperplasia de tecido linfoide, biópsia excisional foi realizada. O exame histopatológico revelou cavidade patológica revestida por epitélio e uma cápsula cística de tecido conjuntivo, contendo tecido linfoide. O diagnóstico de CLEO foi estabelecido. A paciente não apresentou sinais de recidiva após a remoção cirúrgica da lesão.

ABSTRACT Oral lymphoepithelial cyst (OLEC) is an uncommon lesion whose pathogenesis remains poorly understood. The purpose of this paper is to report a case of OLEC. Female patient, white, 62 years old, presented asymptomatic nodular swelling of soft consistency in the lateral border of the tongue. Under the clinical hypothesis of lymphoid tissue hyperplasia, an excisional biopsy was performed. Histopathological examination revealed a pathological epithelial-lined cavity and a cystic connective tissue capsule containing lymphoid tissue. The diagnosis of OLEC was established and the patient showed no signs of recurrence after surgical removal of the lesion.

RESUMEN El quiste linfoepitelial (QLE) oral es una lesión infrecuente, cuya patogénesis es aún poco conocida. El objetivo del presente estudio es reportar un caso de QLE oral. Mujer blanca de 62 años presentó un crecimiento nodular asintomático de consistencia blanda, en borde lateral de la lengua. Bajo la hipótesis clínica de hiperplasia del tejido linfoide, se realizó una biopsia excisional. El examen histopatológico reveló cavidad patológica revestida de epitelio y una cápsula quística de tejido conectivo, conteniendo tejido linfoide. Se estableció el diagnóstico de QLE oral. La paciente no ha presentado recidiva tras extirpación quirúrgica de la lesión.

https://doi.org/10.5935/1676-2444.20200026 4327 downloads

12.

Updated Cardiovascular Prevention Guideline of the Brazilian Society of Cardiology - 2019
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Précoma, Dalton Bertolim

; Oliveira, Gláucia Maria Moraes de

; Simão, Antonio Felipe

; Dutra, Oscar Pereira

; Coelho, Otávio Rizzi

; Izar, Maria Cristina de Oliveira

; Póvoa, Rui Manuel dos Santos

; Giuliano, Isabela de Carlos Back

; Alencar Filho, Aristóteles Comte de

; Machado, Carlos Alberto

; Scherr, Carlos

; Fonseca, Francisco Antonio Helfenstein

; Santos Filho, Raul Dias dos

; Carvalho, Tales de

; Avezum Jr., Álvaro

; Esporcatte, Roberto

; Nascimento, Bruno Ramos

; Brasil, David de Pádua

; Soares, Gabriel Porto

; Villela, Paolo Blanco

; Ferreira, Roberto Muniz

; Martins, Wolney de Andrade

; Sposito, Andrei C.

; Halpern, Bruno

; Saraiva, José Francisco Kerr

; Carvalho, Luiz Sergio Fernandes

; Tambascia, Marcos Antônio

; Coelho-Filho, Otávio Rizzi

; Bertolami, Adriana

; Correa Filho, Harry

; Xavier, Hermes Toros

; Faria-Neto, José Rocha

; Bertolami, Marcelo Chiara

; Giraldez, Viviane Zorzanelli Rocha

; Brandão, Andrea Araújo

; Feitosa, Audes Diógenes de Magalhães

; Amodeo, Celso

; Souza, Dilma do Socorro Moraes de

; Barbosa, Eduardo Costa Duarte

; Malachias, Marcus Vinícius Bolívar

; Souza, Weimar Kunz Sebba Barroso de

; Costa, Fernando Augusto Alves da

; Rivera, Ivan Romero

; Pellanda, Lucia Campos

; Silva, Maria Alayde Mendonça da

; Achutti, Aloyzio Cechella

; Langowiski, André Ribeiro

; Lantieri, Carla Janice Baister

; Scholz, Jaqueline Ribeiro

; Ismael, Silvia Maria Cury

; Ayoub, José Carlos Aidar

; Scala, Luiz César Nazário

; Neves, Mario Fritsch

; Jardim, Paulo Cesar Brandão Veiga

; Fuchs, Sandra Cristina Pereira Costa

; Jardim, Thiago de Souza Veiga

; Moriguchi, Emilio Hideyuki

; Schneider, Jamil Cherem

; Assad, Marcelo Heitor Vieira

; Kaiser, Sergio Emanuel

; Lottenberg, Ana Maria

; Magnoni, Carlos Daniel

; Miname, Marcio Hiroshi

; Lara, Roberta Soares

; Herdy, Artur Haddad

; Araújo, Cláudio Gil Soares de

; Milani, Mauricio

; Silva, Miguel Morita Fernandes da

; Stein, Ricardo

; Lucchese, Fernando Antonio

; Nobre, Fernando

; Griz, Hermilo Borba

; Magalhães, Lucélia Batista Neves Cunha

; Borba, Mario Henrique Elesbão de

; Pontes, Mauro Ricardo Nunes

; Mourilhe-Rocha, Ricardo

Arquivos Brasileiros de Cardiologia

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Out 2019, Volume 113 Nº 4 Páginas 787 - 891

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20190204 40841 downloads

13.

Hierarchical and optimization methods for the characterization of tomato genotypes
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Peixoto, Joicy V. M.

; Almeida, Rafaela S. de

; Rocha, Jaine P. R. da

; Maciel, Gabriel M.

; Santos, Nádya C.

; Pereira, Lucas M.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Jan 2019, Volume 23 Nº 1 Páginas 27 - 32

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Uma correta caracterização de bancos de germoplasma é fundamental para melhoristas obterem sucesso em programas de melhoramento. Várias pesquisas têm buscado obtenção de genótipos com resistência a pragas. No entanto, não há um consenso em relação a qual metodologia é a mais adequada para caracterizar um banco de germoplasma de tomateiro com diferentes níveis de resistência a pragas. O trabalho foi realizado com o objetivo de comparar métodos de análise multivariada para avaliação da diversidade genética em genótipos de tomateiro com diferentes níveis de resistência a pragas. Os experimentos foram conduzidos na Estação Experimental de Hortaliças da Universidade Federal de Uberlândia - campus Monte Carmelo (18º 42’ 43,19” latitude Sul e 47º 29’ 55,8” longitude Oeste, 873 m de altitude), no período de abril de 2013 a novembro de 2016. Foram avaliados dezesseis genótipos provenientes do cruzamento interespecífico entre LA-716 (S. pennellii) versus linhagem pré-comercial (UFU-057) seguido de um retrocruzamento e uma autofecundação, juntamente com a linhagem pré-comercial UFU-057 (genitor recorrente), Santa Clara e o acesso selvagem S. pennellii (genitor doador). Foram analisados os teores de acilaçúcares, tricomas foliares, teste de repelência a traça-do-tomateiro e a larva-minadora. O delineamento experimental foi em blocos ao acaso totalizando 76 parcelas (19 genótipos x 4 blocos). Conclui-se que houve variabilidade genética entre os genótipos avaliados. O método de dispersão gráfica por componentes principais revelou maior poder de discriminação. Os genótipos UFU-057F2RC27#4.3, UFU-057F2RC28#2.2 e UFU-057F2RC27#4.7 contêm os maiores teores de acilaçúcares, resistência a Liriomyza spp. e a T. absoluta.

ABSTRACT The correct characterization of germplasm banks is fundamental for breeders to succeed in breeding programs. Several studies have sought to obtain genotypes with resistance to pests. However, there is no consensus about which methodology is the most appropriate to characterize a germplasm bank of tomato with different levels of resistance to pests. The objective of this study was to compare methods of multivariate analysis for the evaluation of genetic diversity in tomato genotypes with different levels of resistance to pests. The experiments were conducted at the Vegetable Experimental Station of the Federal University of Uberlândia - Monte Carmelo campus (18º 42’ 43.19” South latitude and 47º 29’ 55.8” West longitude, 873 m altitude), in the period from April 2013 to November 2016. Sixteen genotypes were evaluated from the interspecific cross between LA-716 (S. pennellii) versus pre-commercial line (UFU-057) followed by backcrossing and self-fertilization, along with the pre-commercial line UFU-057 (recurrent parent) Santa Clara and the wild accession S. pennellii (donor genitor). The contents of acylsugar, foliar trichomes, South American tomato pinworm and leaf miner repellency tests were analyzed. The experimental design was the randomized block design totaling 76 plots (19 genotypes x 4 blocks). It was concluded that there was genetic variability among the evaluated genotypes. The method of graphic dispersion by principal components revealed a greater power of discrimination. Genotypes UFU-057F2RC27#4.3, UFU-057F2RC28#2.2 and UFU-057F2RC27#4.7 contain the highest levels of acylsugar, resistance to Liriomyza spp. and T. absoluta.

https://doi.org/10.1590/1807-1929/agriambi.v23n1p27-32 886 downloads

14.

PROPERTIES OF PARTICLEBOARD PANELS MADE OF SUGARCANE PARTICLES WITH AND WITHOUT HEAT TREATMENT
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Milagres, Emerson Gomes

; Barbosa, Raiana Augusta Grandal Savino

; Caiafa, Karine Fernandes

; Gomes, Gabriel Soares Lopes

; Castro, Tatiana Aurora Condezo

; Vital, Benedito Rocha

Revista Árvore

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2019, Volume 43 Nº 5 elocation e430502

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo deste trabalho foi determinar as propriedades de painéis aglomerados confeccionados com partículas de bagaço de cana-de-açúcar in natura e aquecidas a 250 °C durante 5 minutos. Foram empregadas várias proporções de partículas na confecção dos painéis e as suas propriedades foram comparadas com as propriedades de um painel fabricado com partículas de Pinus sp. Os painéis foram produzidos com 8% de adesivo à base de tanino formaldeído, 0,5% de emulsão parafínica e prensados a 32 kgf.cm-2, por 10 minutos, à temperatura de 180 °C. Determinou-se a densidade básica das partículas in natura e termotratadas, sua composição química bem como a taxa de compressão necessária para obter painéis com densidade igual a 0,75 g.cm-3. Determinou-se a densidade básica dos painéis, umidade de equilíbrio higroscópico, inchamento em espessura, expansão linear, adsorção de vapor de água, módulo de elasticidade e de ruptura, tração perpendicular, arrancamento de parafuso e dureza Janka. As densidades básicas das partículas de Pinus e do bagaço de cana sem e com tratamento térmico foram de 0,46, 0,27 e 0,30 g.cm-3, respectivamente. A massa específica média dos painéis foi igual a 0,74 g.cm-3 sem diferença significativa entre eles. Geralmente, os painéis fabricados com partículas de cana-de-açúcar foram menos higroscópicos e dimensionalmente mais estáveis do que os painéis fabricados com partículas de Pinus. Contudo, a resistência à tração perpendicular, o arrancamento de parafuso e a dureza de Janka destes painéis foram maiores. O tratamento térmico das partículas de bagaço de cana resultou em melhores propriedades mecânicas de tração perpendicular e dureza de Janka. De modo geral, os painéis estão dentro dos limites estabelecidos pela norma ANSI A208.1. Portanto, é possível substituir painéis confeccionados com partículas de Pinus por bagaço de cana de açúcar, desde de que, pelo menos 25% das partículas sejam tratadas termicamente durante 5 minutos à temperatura de 250ºC.

ABSTRACT The objective of this work was to determine the properties of particleboard panels made of “in natura” sugarcane bagasse particles, heated at 250 °C for 5 minutes. Various particle proportions were utilized to produce the panels and their properties were compared with that of a panel made of Pinus sp. The panels were produced with 8% tannin formaldehyde adhesive, and 0.5% paraffin emulsion, being pressed at 32 kgf.cm-2 for 10 minutes at 180 ° C. It was determined the basic density of the “in natura” and heat-treated particles, their chemical composition, as well as the compression ratio necessary to obtain panels with density equal to 0.75 g.cm-3. The basic density of the panels, hygroscopic equilibrium humidity, thickness swelling, linear expansion, water vapor adsorption, modulus of elasticity and rupture, perpendicular traction, screw pullout, and Janka hardness were determined. The basic densities of Pinus particles and sugarcane bagasse without and with heat treatment were 0.46, 0.27 and 0.30 g.cm-3, respectively. The average specific mass of the panels was 0.74 g.cm-3 with no significant difference between them. Generally, panels made of sugarcane particles were less hygroscopic and dimensionally more stable than panels made of Pinus particles. However, the perpendicular tensile strength, screw pullout and Janka hardness of these panels were higher than for the Pinus panels. The heat treatment of sugarcane bagasse particles resulted in better mechanical properties of perpendicular traction and Janka hardness. In general, the panels are within the limits set by ANSI A208.1. It is therefore possible to replace panels made of Pinus particles for the ones made of sugarcane bagasse, provided that at least 25% of the particles are heat treated for 5 minutes at 250 ° C.

https://doi.org/10.1590/1806-90882019000500002 758 downloads

15.

Evaluation of methods for the quantification of ether extract contents in forage and cattle feces
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BARBOSA, MARCÍLIA M.

; DETMANN, EDENIO

; VALADARES FILHO, SEBASTIÃO C.

; DETMANN, KELLY S.C.

; FRANCO, MARCIA O.

; BATISTA, ERICK D.

; ROCHA, GABRIEL C.

Anais da Academia Brasileira de Ciências

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Jun 2017, Volume 89 Nº 2 Páginas 1295 - 1303

Resumo: En | Texto: En | PDF: En

ABSTRACT The objective of this study was to compare the estimates of ether extract (EE) contents obtained by the Randall method and by the high-temperature method of the American Oil Chemist's Society (AOCS; Am 5-04) in forages (n = 20) and cattle feces (n = 15). The EE contents were quantified by using the Randall extraction or AOCS method and XT4 filter bags or cartridges made of qualitative filter paper (80 g/m²) as containers for the samples. It was also evaluated the loss of particles, and concentration of residual chlorophyll after extraction and the recovery of protein and minerals in the material subjected to extraction. Significant interaction was observed between extraction method and material for EE contents. The EE estimates using the AOCS method were higher, mainly in forages. No loss of particles was observed with different containers. The chlorophyll contents in the residues of cattle feces were not affected by the extraction method; however, residual chlorophyll was lower using the AOCS method in forages. There was complete recovery of the protein and ash after extraction. The results suggest that AOCS method produces higher estimates of EE contents in forages and cattle feces, possibly by providing greater extraction of non-fatty EE.

https://doi.org/10.1590/0001-3765201720160708 5855 downloads

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