SUMMARY OBJECTIVE: This study aims to investigate the association between the immunohistochemical expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and plasma zinc in women with fibroadenoma. METHODS: This cross-sectional study included 37 premenopausal women with fibroadenoma. Waist circumference and body mass index of the participants were measured. Plasma zinc concentrations were determined using atomic flame absorption spectrophotometry. Fragments of breast tissue were fixed and incubated with primary mouse monoclonal antibodies (monoclonal antibodies matrix metalloproteinase -2 -507 and monoclonal antibodies matrix metalloproteinase -9-439). Semi-quantitative analysis of matrix metalloproteinase-2 and matrix metalloproteinase-9 immunoreactivity was performed. Spearman’s test and Friedman’s test were used for statistical analyses. The p<0.05 were considered statistically significant. RESULTS: The average age of the participants was 32.81±9.51 years. The body mass index and waist circumference values were within the normal range. The mean plasma zinc concentration was 42.73±13.84 µg/dL, with 94.6% inadequacy. A statistically significant difference was found between the positive expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 (p=0.0184). There was no significant correlation between the matrix metalloproteinase expression and the plasma zinc levels. CONCLUSIONS: Women with fibroadenoma had hypozincemia and positive expression of metalloproteinases.

RESUMO Objetivou-se compreender a experiência formativa realizada por meio de lives, com a temática “educação em saúde”, durante o confinamento social imposto pela Covid-19. Desenvolveu-se uma pesquisa de abordagem qualitativa, do tipo pesquisa-ação, que utilizou lives como veículo para a ação formativa. Realizaram-se nove lives: a maioria dos conteúdos educativos veiculados partiu da demanda do hospital e versava sobre o enfrentamento da Covid-19. Concluiu-se que as lives se apresentam como ferramentas importantes para operacionalizar a educação permanente em saúde, especialmente em contexto de pandemia, no entanto, elas excluem usuários do sistema público de saúde de maior vulnerabilidade social, que não possuem acesso à tecnologia móvel conectada à Internet.

ABSTRACT The objective was to understand the training experience carried out through online live videos called lives with the theme “health education”, during the social confinement imposed by COVID-19. A qualitative research-action was developed, which used lives as a vehicle for formative action. Nine lives were held: most of the educational content conveyed came from the demand of the hospital and dealt with coping with COVID-19. It is concluded that lives are presented as important tools to operationalize permanent health education, especially in the context of a pandemic. However, they excluded users of the public health system of greatest social vulnerability, who do not have access to mobile technology connected to the Internet.

RESUMEN Se objetivó comprender la experiencia de capacitación realizada mediante lives con el tema “educación para la salud” durante el encierro social impuesto por el COVID-19. Se desarrolló una investigación cualitativa de investigación-acción, que utilizaba lives como vehículo para la acción formativa. Se realizaron nueve lives: la mayor parte del contenido educativo transmitido provino de la demanda del hospital y se ocupó de hacer frente al COVID-19. Se concluyó que las lives se presentan como herramientas importantes para poner en práctica la educación permanente en salud, especialmente en el contexto de una pandemia; sin embargo, excluyen a los usuarios del sistema de salud pública de mayor vulnerabilidad social, que no tienen acceso a la tecnología móvil conectada a Internet.